CN114903826A - Anti-aging composition, anti-aging cosmetic and preparation method thereof - Google Patents
Anti-aging composition, anti-aging cosmetic and preparation method thereof Download PDFInfo
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- CN114903826A CN114903826A CN202210479160.3A CN202210479160A CN114903826A CN 114903826 A CN114903826 A CN 114903826A CN 202210479160 A CN202210479160 A CN 202210479160A CN 114903826 A CN114903826 A CN 114903826A
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- aging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
The invention discloses an anti-aging composition, an anti-aging cosmetic and a preparation method thereof, belonging to the technical field of cosmetics; the anti-aging composition comprises aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, a centella asiatica extract and a malus micromalus extract; the anti-aging composition provided by the invention has excellent anti-aging effect through the synergistic effect of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella extract and apple extract; the anti-aging composition provided by the invention is natural in source, and is applied to anti-aging cosmetics, so that the obtained cosmetics are mild and have no stimulation; meanwhile, the anti-aging cosmetic provided by the invention is simple in preparation method and simple and convenient to operate.
Description
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to an anti-aging composition, an anti-aging cosmetic and a preparation method thereof.
Background
Skin aging is mainly manifested by degenerative changes in the form and physiology of collagen fibers, elastic fibers and matrices. The remarkable characteristics are as follows: loss of elastic suppleness, appearance of wrinkles, dry keratosis, dullness and excessive deposition of pigmented spots. In order to maintain a youthful skin state, more and more consumers use cosmetics having an anti-aging effect. Skin aging has a range of causes including intrinsic cell proliferation and loss of repair capacity, and external environmental damage. In the prior art, the efficacy of anti-aging cosmetics mostly depends on single powerful raw materials, such as retinol, and the raw materials have the problems of high irritation, intolerance and the like.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a mild and effective anti-aging composition, an anti-aging cosmetic and a preparation method thereof.
In order to achieve the purpose, the invention adopts the technical scheme that: an anti-aging composition comprising aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella asiatica extract, and malus micromalus extract.
According to the anti-aging composition provided by the invention, the aminobutyric acid, the hydrolyzed collagen, the hydrolyzed sodium hyaluronate, the centella extract and the apple extract are matched and combined to generate a synergistic effect, so that the obtained anti-aging composition is mild and has a remarkable effect; wherein aminobutyric acid is a naturally occurring non-protein amino acid, widely found in vertebrates, plants and microorganisms. Has effects in inhibiting nerve excitation, relaxing muscle, promoting collagen synthesis, repairing epidermis, and retaining water; the hydrolyzed collagen has super-strong moisturizing performance, can maintain the skin moisture, has obvious anti-aging effect, endows the skin with the characteristic of compact Q elasticity, and can also improve blood circulation and improve the immune system so as to smooth the skin; the hydrolyzed sodium hyaluronate can enter deep skin to a dermis layer through pores and intercellular spaces, so that a substrate repairing effect which cannot be achieved by the conventional sodium hyaluronate is exerted, and the effects of repairing damaged cells of the skin, promoting nutrient absorption of the skin, removing superoxide radicals, improving the water content of the muscle bottom, promoting the improvement of the skin resistance, increasing the skin elasticity, delaying aging, resisting inflammation and the like are achieved; the centella asiatica extract is rich in asiaticoside, has good anti-inflammatory effect, can inhibit expression of COX-2 and PAR-2 induced by UVB, and has effects of promoting in vivo collagen synthesis and facilitating wound healing; the Malus micromalus Linn extract has strong antioxidant and free radical scavenging effects, and can effectively scavenge free radicals harmful to skin and relieve skin injury caused by ultraviolet irradiation.
As a preferred embodiment of the anti-aging composition of the present invention, the hydrolyzed sodium hyaluronate has a molecular weight of < 10000 Da.
When the selected hydrolyzed sodium hyaluronate is oligomeric sodium hyaluronate, namely the molecular weight is within the range, the molecular weight of the selected hydrolyzed sodium hyaluronate is relatively small, and the selected hydrolyzed sodium hyaluronate can more fully enter the deep part of the skin to the dermis layer through pores and intercellular spaces; thereby exerting the substrate repairing effect which can not be achieved by the conventional sodium hyaluronate.
As a preferred embodiment of the antiaging composition of the invention, the mass ratio of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella asiatica extract and malus extract is aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: malus baccata extract ═ (0.1-3): (0.05-1): (0.01-0.1): (0.08-3): (0.08-3).
When the ratio of aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: malus baccata extract ═ (0.1-3): (0.05-1): (0.01-0.1): (0.08-3): (0.08-3), the obtained anti-aging composition has good ability to scavenge free radicals and excellent anti-aging effect.
As a preferred embodiment of the antiaging composition of the invention, the mass ratio of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella asiatica extract and malus extract is aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: malus baccata extract ═ (0.2-1.5): (0.08-0.5): (0.03-0.05): (0.1-1): (0.15-1).
When the ratio of aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: malus baccata extract ═ (0.2-1.5): (0.08-0.5): (0.03-0.05): (0.1-1): (0.15-1), the anti-aging effect of the obtained composition is more remarkable.
As a preferred embodiment of the antiaging composition of the invention, the mass ratio of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella asiatica extract and malus extract is aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: 0.25 parts of malus domestica extract: 0.1: 0.04: 0.4: 0.3; when the mass ratio of the five components is in the proportion, the obtained anti-aging composition has the strongest capacity of eliminating free radicals and the most prominent anti-aging effect.
In addition, the invention also provides an anti-aging cosmetic which comprises the anti-aging composition.
As a preferred embodiment of the anti-aging cosmetic, the anti-aging cosmetic comprises the following components in percentage by mass: 0.01-3% of aminobutyric acid, 0.01-1% of hydrolyzed collagen, 0.01-0.1% of hydrolyzed sodium hyaluronate, 0.01-3% of centella asiatica extract and 0.01-3% of malus extract.
As a preferable embodiment of the anti-aging cosmetic of the present invention, the anti-aging composition is contained in the anti-aging cosmetic in an amount of 0.3 to 12% by mass.
As a preferable embodiment of the anti-aging cosmetic of the present invention, the anti-aging composition is present in the anti-aging cosmetic in an amount of 0.6 to 4% by mass.
When the addition amount of the anti-aging composition in the anti-aging cosmetic is 0.3-12%, especially 0.6-4%, the obtained anti-aging cosmetic has an excellent anti-aging effect on the one hand, and on the other hand, the limitation that the further addition effect of the anti-aging cosmetic is not obviously increased is avoided.
As a preferred embodiment of the anti-aging cosmetic of the present invention, the anti-aging cosmetic further comprises the following components by mass: 5-15% of cosmetic matrix and the balance of deionized water.
As a preferred embodiment of the anti-aging cosmetic of the present invention, the cosmetic base includes a moisturizing agent, a thickening agent, and a skin conditioning agent.
As a preferred embodiment of the anti-aging cosmetic of the present invention, the moisturizer comprises glycerin, butylene glycol, and 1, 2-hexanediol.
As a preferred embodiment of the antiaging cosmetic preparation of the invention, the thickener includes xanthan gum, polyacrylate crosspolymer-6.
As a preferred embodiment of the anti-aging cosmetic of the present invention, the skin conditioner includes EDTA-disodium, p-hydroxyacetophenone.
As a preferred embodiment of the anti-aging cosmetic, the anti-aging cosmetic comprises the following components in percentage by mass: 2-4% of glycerol, 2-4% of butanediol, 0.5-0.6% of 1, 2-hexanediol, 0.05-0.08% of xanthan gum, 60.8-1.2% of polyacrylate cross-linked polymer, 0.03-0.05% of EDTA-disodium and 0.5-0.6% of p-hydroxyacetophenone.
As a preferred embodiment of the antiaging cosmetic composition of the invention, the antiaging cosmetic composition is in the form of a liquid, emulsion, cream or solid.
In addition, the invention also provides a preparation method of the anti-aging cosmetic, which comprises the following steps: mixing cosmetic matrix and deionized water, dispersing at 70-90 deg.C, keeping the temperature for 15-25 min, cooling to 40-50 deg.C, adding the above materials, and stirring to obtain antiaging cosmetic.
Compared with the prior art, the invention has the following beneficial effects:
firstly, the method comprises the following steps: the anti-aging composition provided by the invention has excellent anti-aging effect through the synergistic effect of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella extract and apple extract;
secondly, the method comprises the following steps: the anti-aging composition provided by the invention is natural in source, and is applied to anti-aging cosmetics, so that the obtained cosmetics are mild and have no stimulation;
thirdly, the method comprises the following steps: the anti-aging cosmetic provided by the invention is simple in preparation method and simple and convenient to operate.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
The raw materials used in the examples and comparative examples of the present invention are available from conventional commercial sources unless otherwise specified; wherein the extract of centella asiatica (CENTELLA ASIATICA) is obtained from Clojie Biotech, Inc., Guangzhou under the brand name of centella asiatica extract C-I; the extract of Malus pumila (LIMONIA ACIDISIA) is purchased from Tojie Biotech, Inc. of Guangzhou city under the brand name of Tanaka extract C-I; hydrolyzed sodium hyaluronate (molecular weight < 10000Da) purchased from Huaxi Biotech Co., Ltd under the brand name of Nano
Carrying out enzyme digestion on oligomeric sodium hyaluronate; sodium hyaluronate (molecular weight 100-180 Da) is purchased from Huaxi Biotechnology corporation under the trade name Hybloom TM Sodium hyaluronate (HA-T).
Examples 1-5 and comparative examples 6-11 each relate to an antiaging composition, and comparative examples 1-5 relate to one of the antiaging compositions, the kind of which is shown in Table 1;
table 1: antisenescence composition or its component (weight portion)
Effect example 1
Effect examples of the present invention the radical scavenging abilities of the products obtained in examples 1 to 5 and comparative examples 1 to 11 were investigated, wherein the radical scavenging abilities of DPPH radicals, superoxide anion radicals and hydroxyl radicals were mainly investigated; specifically; the results obtained are shown in table 2;
1. the test for DPPH radical scavenging ability comprises the following steps:
adding 3mL of phosphate buffer solution with the pH value of 6.8, 4mL of 0.4mmol/L of DPPH absolute ethanol solution and 0.2mL of sample to be detected into a 10mL centrifuge tube in sequence, fully mixing the solutions, centrifuging the mixture for 10min (8000r/min) after 30min, taking supernatant, measuring the absorbance value at 516nm, performing parallel operation for 3 times, and taking an average value, wherein the clearance rate of the sample to DPPH free radicals is [ 1- (A1-A2)/A3 ]. Wherein A1 is absorbance value of DPPH solution after sample reaction, A2 is absorbance value of sample solution without DPPH (replaced by absolute ethyl alcohol), and A3 is absorbance value of sample solution with DPPH and aqueous solution.
2. The test for superoxide anion inhibition comprises the following steps:
a buffer system (Tris-HCl-EDTA) with a pH value of 8.20 was prepared. Adding 0.6mL of sample to be detected into a 10mL centrifuge tube, adding 5.2mL of buffer solution, adding 0.045mol/L of pyrogallol solution into 0.2mL by a pipette, quickly shaking up, quickly putting into a dry cuvette after waiting for 5 minutes of reaction (time must be accurate), measuring the absorbance value at 325nm, and recording as A0, and measuring as A4 after 10 minutes. The absorbance values measured with distilled water instead of the sample were designated as B0 and B4, respectively. The average value is obtained by parallel operation for 3 times, and the inhibition ratio of the sample to the superoxide anion is [ (B4-B0) - (A4-A0) ]/(B4-B0).
3. The test for hydroxyl radical scavenging ability comprises the following steps:
adding 1mL, 0.4mmol/L crystal violet, 3mL, 0.2mol/L pH7.4 phosphate buffer solution, 1mL, 0.001mol/LFeSO4 solution and 1mL of sample to be tested into a 10mL centrifuge tube, and finally adding 1mL 30% H 2 O 2 Starting the reaction, centrifuging at 12000r/min for 5min after reacting for 1H at room temperature, taking supernatant, measuring the light absorption value at 510nm and recording as C, using distilled water to replace the sample and recording as C1, using distilled water to replace the sample and H 2 O 2 The absorbance was designated as C2. The mean values were taken from 3 parallel runs and the hydroxyl radical clearance of the sample was (C-C1)/(C2-C1).
Table 2: scavenging ability of products obtained in examples 1 to 5 and comparative examples 1 to 11 for free radicals
As can be seen from Table 2, the antiaging compositions according to examples 1 to 5 of the present invention have a strong radical-scavenging ability, and exhibit a significant scavenging-inhibiting effect on DPPH radicals, superoxide anion radicals and hydroxyl radicals, preferably examples 3 to 5, and most preferably example 5; in addition, as can be seen from example 5 and comparative examples 1-10, under the same conditions, the radical clearance rate is significantly lower than that of the composition of the present invention when any one of 5 components is used alone or one of 5 components is not used, further indicating that the composition of the present invention needs to achieve a significant anti-aging effect under the synergistic effect of 5 compositions; in addition, it can be seen from comparative example 11 that, although the composition obtained in comparative example 11 has a certain scavenging effect on radicals, the scavenging effect is significant only when the mass ratio of the antiaging composition is within the range given by the invention.
Examples 6 to 10, comparative example 12
Examples 6 to 10 and comparative example 12 provided by the invention are all anti-aging essence, the composition table of the essence is shown in table 3, wherein data in the table are filled in according to mass percentage;
table 3: composition tables of essence solutions of control group, examples 6 to 10 and comparative example 12
The preparation methods of the essences of examples 6 to 10 and comparative example 12 include the following steps: mixing the raw materials except the components of the anti-aging composition in the table 3, putting the raw materials into an emulsifying pot, uniformly dispersing the raw materials at 80 ℃, keeping the temperature for 20 minutes, cooling the mixture to 40-45 ℃, adding the raw materials of the anti-aging composition, and uniformly stirring the mixture to obtain anti-aging essence; the preparation method of the control group is completely the same as the preparation methods of examples 6 to 10 and comparative example 12 except that the raw materials of the anti-aging composition are not added;
effect example 2
The prepared control group, examples 6 to 10 and comparative example 12 were subjected to a stability test in which the heat resistance test was conducted by allowing to stand at 45 + -2 deg.C for one month and observing the appearance, color and smell thereof; the cold resistance test is to stand for one month at the temperature of minus 18 +/-2 ℃ and observe the appearance, color and smell of the product; the cold and hot cyclicity test is that the materials are stored for 24 hours at the temperature of 45 ℃, normal temperature and minus 18 ℃ respectively, and are circulated for 3 times to observe the appearance, color and smell of the materials; the test results showed that the prepared products of the control, examples 6 to 10 and comparative example 12 were good in stability, and heat-resistant, cold-resistant and did not give abnormal appearance, color and smell under cold and heat cycles.
Effect example 3
The anti-aging effect of the prepared products of the control group, examples 6 to 10 and comparative example 12 was studied in the volunteer test mode in this effect example; the method specifically comprises the following steps:
1. screening volunteers: selecting 21 volunteers, randomly dividing all the volunteers into 7 groups according to 3 persons in each group, and respectively trying a control group, examples 6-10 and a comparative example 12 on each group of volunteers;
(1) inclusion volunteer criteria were: female aged 38-55 years old; hormone drugs and immunosuppressants have not been used in the last month; the tested part does not participate in other clinical testers at present or in nearly 30 days; can be matched with testers well; the system can read and understand all contents of the informed consent and voluntarily sign the informed consent; during the test period, the consent was not to use any cosmetics, drugs and nutraceuticals that have an impact on the outcome.
(2) Exclusion criteria: patients with open wounds or erosive faces; those with high allergic constitution; those with a history of cosmetic allergy; a female who is pregnant, lactating, or intended to be pregnant during the test; severe center of gravity, liver and kidney function damage and severe immunologic hypofunction; those with mental disorders, severe endocrine disorders, and oral contraceptives; the patients who participate in the drug clinical testers or other testers within 30 days, or the patients who have systemic drugs which have influence on the test results within about 1 week; those who had oral and topical cosmetic products within 2 weeks that may have an effect on the outcome of the test; the investigator considered not appropriate for attending the investigator.
(3) Abort and exit criteria: smearing the tested sample or recording the revisit according to the requirement during the test period; has serious diseases or serious adverse reactions during the use.
2. The test method comprises the following steps: the volunteers use the product on the whole face for 28 days after cleaning the face in the morning and at night every day; before use, the VISIA skin test instrument is used for testing wrinkles, after 28 days of continuous use, the VISIA skin detector is used for testing wrinkles again, the wrinkle fading rate automatically analyzed and calculated by the VISIA skin detector is obtained, and the record is shown in Table 4;
table 4: anti-wrinkle test Table for products obtained in control, examples 6 to 10 and comparative example 12
As can be seen from table 4, the anti-aging cosmetic provided by the present invention has an obvious wrinkle-lightening effect, wherein the anti-wrinkle effect of the essences obtained in examples 8 to 10 is more obvious; in addition, as can be seen from example 10 and comparative example 12, when the molecular weight of sodium hyaluronate used is too large, the degree of improvement of wrinkles by the resulting product is reduced.
Finally, it should be noted that the above embodiments are intended to illustrate the technical solutions of the present invention and not to limit the scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications and equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (10)
1. An anti-aging composition comprising aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, an extract of centella asiatica, and an extract of Malus pumila.
2. The anti-aging composition according to claim 1, wherein the hydrolyzed sodium hyaluronate has a molecular weight of < 10000 Da.
3. The anti-aging composition according to claim 2, wherein the mass ratio of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella asiatica extract and malus micromalus extract is aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: malus baccata extract ═ (0.1-3): (0.05-1): (0.01-0.1): (0.08-3): (0.08-3).
4. The anti-aging composition according to claim 3, wherein the mass ratio of aminobutyric acid, hydrolyzed collagen, hydrolyzed sodium hyaluronate, centella asiatica extract and malus micromalus extract is aminobutyric acid: hydrolyzing collagen: hydrolysis of sodium hyaluronate: centella asiatica extract: malus baccata extract ═ (0.2-1.5): (0.08-0.5): (0.03-0.05): (0.1-1): (0.15-1).
5. An antiaging cosmetic characterized in that it comprises the antiaging composition as claimed in any one of claims 1 to 4.
6. The anti-aging cosmetic according to claim 5, comprising the following components in percentage by mass: 0.01-3% of aminobutyric acid, 0.01-1% of hydrolyzed collagen, 0.01-0.1% of hydrolyzed sodium hyaluronate, 0.01-3% of centella asiatica extract and 0.01-3% of malus extract.
7. The antiaging cosmetic according to claim 5, wherein the antiaging composition is contained in an amount of 0.3 to 12% by mass.
8. The anti-aging cosmetic according to claim 5, further comprising the following components in mass percent: 5-15% of cosmetic matrix and the balance of deionized water.
9. The anti-aging cosmetic product of claim 5, wherein the cosmetic base comprises moisturizers, thickeners, and skin conditioners.
10. The method for preparing an antiaging cosmetic according to claim 9, characterized in that the method comprises the steps of: mixing cosmetic matrix and deionized water, dispersing at 70-90 deg.C, keeping the temperature for 15-25 min, cooling to 40-50 deg.C, adding the above materials, and stirring to obtain antiaging cosmetic.
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080311234A1 (en) * | 2004-03-24 | 2008-12-18 | Tadashi Yoneda | Oil-in-Water Emulsified Composition, and External Preparation for Skin and Cosmetics Using the Composition |
| CN110339132A (en) * | 2019-08-16 | 2019-10-18 | 宁波范思黎化妆品科技有限公司 | A kind of snail collagen U.S. flesh facial mask |
| CN110664635A (en) * | 2019-11-05 | 2020-01-10 | 湖北创界生物科技有限公司 | Moisturizing and hydrating mask composition, mask and preparation method of mask |
| CN113925791A (en) * | 2021-09-29 | 2022-01-14 | 广州卓芬化妆品有限公司 | Waterproof sunscreen composition and preparation method thereof |
| CN114983900A (en) * | 2022-06-22 | 2022-09-02 | 杭州水芭莎生物医药科技有限公司 | Preparation method of emulsion with antioxidant and repairing effects |
-
2022
- 2022-04-29 CN CN202210479160.3A patent/CN114903826B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080311234A1 (en) * | 2004-03-24 | 2008-12-18 | Tadashi Yoneda | Oil-in-Water Emulsified Composition, and External Preparation for Skin and Cosmetics Using the Composition |
| CN110339132A (en) * | 2019-08-16 | 2019-10-18 | 宁波范思黎化妆品科技有限公司 | A kind of snail collagen U.S. flesh facial mask |
| CN110664635A (en) * | 2019-11-05 | 2020-01-10 | 湖北创界生物科技有限公司 | Moisturizing and hydrating mask composition, mask and preparation method of mask |
| CN113925791A (en) * | 2021-09-29 | 2022-01-14 | 广州卓芬化妆品有限公司 | Waterproof sunscreen composition and preparation method thereof |
| CN114983900A (en) * | 2022-06-22 | 2022-09-02 | 杭州水芭莎生物医药科技有限公司 | Preparation method of emulsion with antioxidant and repairing effects |
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