CN114886983B - Traditional Chinese medicine composition for improving polycystic ovarian syndrome and preparation method thereof - Google Patents
Traditional Chinese medicine composition for improving polycystic ovarian syndrome and preparation method thereof Download PDFInfo
- Publication number
- CN114886983B CN114886983B CN202210587950.3A CN202210587950A CN114886983B CN 114886983 B CN114886983 B CN 114886983B CN 202210587950 A CN202210587950 A CN 202210587950A CN 114886983 B CN114886983 B CN 114886983B
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- root
- polycystic ovary
- ovary syndrome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 66
- 201000010065 polycystic ovary syndrome Diseases 0.000 title claims abstract description 54
- 239000000203 mixture Substances 0.000 title claims abstract description 42
- 238000002360 preparation method Methods 0.000 title abstract description 16
- 206010036049 Polycystic ovaries Diseases 0.000 title description 2
- 239000009636 Huang Qi Substances 0.000 claims abstract description 20
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 244000150195 Cyperus longus Species 0.000 claims abstract description 17
- 241000893536 Epimedium Species 0.000 claims abstract description 17
- 235000018905 epimedium Nutrition 0.000 claims abstract description 17
- 241000234276 Curculigo Species 0.000 claims abstract description 16
- 241000830535 Ligustrum lucidum Species 0.000 claims abstract description 16
- 241000405414 Rehmannia Species 0.000 claims abstract description 16
- 240000007164 Salvia officinalis Species 0.000 claims abstract description 16
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 16
- 241000123589 Dipsacus Species 0.000 claims abstract description 15
- 241000212322 Levisticum officinale Species 0.000 claims abstract description 14
- 239000001645 levisticum officinale Substances 0.000 claims abstract description 14
- 241000005787 Cistanche Species 0.000 claims abstract description 13
- 241000756943 Codonopsis Species 0.000 claims abstract description 13
- 244000286838 Eclipta prostrata Species 0.000 claims abstract description 13
- 235000014066 European mistletoe Nutrition 0.000 claims abstract description 13
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 13
- 235000012300 Rhipsalis cassutha Nutrition 0.000 claims abstract description 13
- 210000000582 semen Anatomy 0.000 claims abstract description 11
- 241000096284 Gynochthodes officinalis Species 0.000 claims abstract description 9
- 235000005412 red sage Nutrition 0.000 claims abstract description 9
- 235000018109 Cyperus longus Nutrition 0.000 claims abstract 3
- 244000075634 Cyperus rotundus Species 0.000 claims abstract 3
- 244000170916 Paeonia officinalis Species 0.000 claims abstract 3
- 244000152640 Rhipsalis cassutha Species 0.000 claims abstract 3
- 235000005010 Scirpus paludosus Nutrition 0.000 claims abstract 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 32
- 239000000463 material Substances 0.000 claims description 31
- 239000000843 powder Substances 0.000 claims description 21
- 238000007873 sieving Methods 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 16
- 241000382455 Angelica sinensis Species 0.000 claims description 13
- 238000001914 filtration Methods 0.000 claims description 13
- 238000001035 drying Methods 0.000 claims description 11
- 239000000706 filtrate Substances 0.000 claims description 6
- 238000010298 pulverizing process Methods 0.000 claims description 6
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 4
- 241000336291 Cistanche deserticola Species 0.000 claims description 3
- 240000007371 Cuscuta campestris Species 0.000 claims description 3
- 239000012467 final product Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 36
- 210000003734 kidney Anatomy 0.000 abstract description 25
- 238000005728 strengthening Methods 0.000 abstract description 20
- 230000001737 promoting effect Effects 0.000 abstract description 13
- 210000000952 spleen Anatomy 0.000 abstract description 13
- 230000017531 blood circulation Effects 0.000 abstract description 7
- 244000061520 Angelica archangelica Species 0.000 abstract description 3
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract description 3
- 230000001225 therapeutic effect Effects 0.000 abstract description 2
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 2
- 210000004185 liver Anatomy 0.000 description 26
- 208000002193 Pain Diseases 0.000 description 25
- 239000008280 blood Substances 0.000 description 25
- 210000004369 blood Anatomy 0.000 description 25
- 239000000047 product Substances 0.000 description 23
- 230000005906 menstruation Effects 0.000 description 19
- 208000024891 symptom Diseases 0.000 description 19
- 230000007812 deficiency Effects 0.000 description 16
- 230000001105 regulatory effect Effects 0.000 description 16
- 210000000988 bone and bone Anatomy 0.000 description 11
- 210000003127 knee Anatomy 0.000 description 11
- 208000019255 Menstrual disease Diseases 0.000 description 10
- 241001106477 Paeoniaceae Species 0.000 description 10
- 241000221012 Viscum Species 0.000 description 10
- 229940079593 drug Drugs 0.000 description 10
- 210000002435 tendon Anatomy 0.000 description 10
- 208000000509 infertility Diseases 0.000 description 8
- 230000036512 infertility Effects 0.000 description 8
- 231100000535 infertility Toxicity 0.000 description 8
- 244000236521 Bupleurum rotundifolium Species 0.000 description 7
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 description 7
- 241000110637 Cuscuta chinensis Species 0.000 description 7
- 206010037660 Pyrexia Diseases 0.000 description 7
- 235000017276 Salvia Nutrition 0.000 description 7
- 208000002173 dizziness Diseases 0.000 description 7
- 235000017524 noni Nutrition 0.000 description 7
- 241000007126 Codonopsis pilosula Species 0.000 description 6
- 241000157491 Morinda Species 0.000 description 6
- 208000008589 Obesity Diseases 0.000 description 6
- 206010041497 Spermatorrhoea Diseases 0.000 description 6
- 230000003213 activating effect Effects 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 6
- 235000020824 obesity Nutrition 0.000 description 6
- 208000002874 Acne Vulgaris Diseases 0.000 description 5
- 208000006820 Arthralgia Diseases 0.000 description 5
- 206010012735 Diarrhoea Diseases 0.000 description 5
- 206010027514 Metrorrhagia Diseases 0.000 description 5
- 208000009205 Tinnitus Diseases 0.000 description 5
- 206010000496 acne Diseases 0.000 description 5
- 230000004087 circulation Effects 0.000 description 5
- 201000001881 impotence Diseases 0.000 description 5
- 208000014674 injury Diseases 0.000 description 5
- 231100000886 tinnitus Toxicity 0.000 description 5
- 230000008736 traumatic injury Effects 0.000 description 5
- 208000004998 Abdominal Pain Diseases 0.000 description 4
- 201000000736 Amenorrhea Diseases 0.000 description 4
- 206010001928 Amenorrhoea Diseases 0.000 description 4
- 206010007247 Carbuncle Diseases 0.000 description 4
- 208000005171 Dysmenorrhea Diseases 0.000 description 4
- 206010013935 Dysmenorrhoea Diseases 0.000 description 4
- 241000316342 Taxillus Species 0.000 description 4
- 231100000540 amenorrhea Toxicity 0.000 description 4
- 230000002124 endocrine Effects 0.000 description 4
- 230000002708 enhancing effect Effects 0.000 description 4
- 210000003414 extremity Anatomy 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000027939 micturition Effects 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 239000002699 waste material Substances 0.000 description 4
- 201000004384 Alopecia Diseases 0.000 description 3
- 206010010774 Constipation Diseases 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 3
- 244000236658 Paeonia lactiflora Species 0.000 description 3
- 235000008598 Paeonia lactiflora Nutrition 0.000 description 3
- 206010039792 Seborrhoea Diseases 0.000 description 3
- 210000001015 abdomen Anatomy 0.000 description 3
- 231100000360 alopecia Toxicity 0.000 description 3
- 239000003098 androgen Substances 0.000 description 3
- 230000001276 controlling effect Effects 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 238000000605 extraction Methods 0.000 description 3
- 230000004438 eyesight Effects 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 230000007721 medicinal effect Effects 0.000 description 3
- 230000002175 menstrual effect Effects 0.000 description 3
- 230000016087 ovulation Effects 0.000 description 3
- 230000002028 premature Effects 0.000 description 3
- 208000008742 seborrheic dermatitis Diseases 0.000 description 3
- 230000001502 supplementing effect Effects 0.000 description 3
- 230000002195 synergetic effect Effects 0.000 description 3
- 230000009044 synergistic interaction Effects 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 201000005670 Anovulation Diseases 0.000 description 2
- 206010002659 Anovulatory cycle Diseases 0.000 description 2
- 241000202726 Bupleurum Species 0.000 description 2
- 206010008479 Chest Pain Diseases 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 208000000059 Dyspnea Diseases 0.000 description 2
- 206010013975 Dyspnoeas Diseases 0.000 description 2
- 208000010228 Erectile Dysfunction Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010020112 Hirsutism Diseases 0.000 description 2
- 241000112528 Ligusticum striatum Species 0.000 description 2
- 208000037093 Menstruation Disturbances Diseases 0.000 description 2
- 206010027339 Menstruation irregular Diseases 0.000 description 2
- 240000002853 Nelumbo nucifera Species 0.000 description 2
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 2
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 208000012886 Vertigo Diseases 0.000 description 2
- 229940030486 androgens Drugs 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- 231100000552 anovulation Toxicity 0.000 description 2
- 210000000038 chest Anatomy 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 230000001815 facial effect Effects 0.000 description 2
- 230000001605 fetal effect Effects 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 230000003821 menstrual periods Effects 0.000 description 2
- 206010029410 night sweats Diseases 0.000 description 2
- 230000036565 night sweats Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 231100000889 vertigo Toxicity 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010000234 Abortion spontaneous Diseases 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 206010006298 Breast pain Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 241000336315 Cistanche salsa Species 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 208000017701 Endocrine disease Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 206010018045 Gastroptosis Diseases 0.000 description 1
- 208000034507 Haematemesis Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 206010019909 Hernia Diseases 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010021033 Hypomenorrhoea Diseases 0.000 description 1
- 206010021118 Hypotonia Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 241000488974 Loranthus Species 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 208000006662 Mastodynia Diseases 0.000 description 1
- 244000131360 Morinda citrifolia Species 0.000 description 1
- 235000008898 Morinda citrifolia Nutrition 0.000 description 1
- 235000008248 Morinda citrifolia var citrifolia Nutrition 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 235000008708 Morus alba Nutrition 0.000 description 1
- 206010038084 Rectocele Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 206010046543 Urinary incontinence Diseases 0.000 description 1
- 206010046814 Uterine prolapse Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 206010047642 Vitiligo Diseases 0.000 description 1
- 208000031975 Yang Deficiency Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 201000006549 dyspepsia Diseases 0.000 description 1
- 208000030172 endocrine system disease Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 208000017561 flaccidity Diseases 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 201000010066 hyperandrogenism Diseases 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 208000007106 menorrhagia Diseases 0.000 description 1
- 230000006371 metabolic abnormality Effects 0.000 description 1
- 208000015994 miscarriage Diseases 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 206010036596 premature ejaculation Diseases 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000552 rheumatic effect Effects 0.000 description 1
- 208000013220 shortness of breath Diseases 0.000 description 1
- 208000000995 spontaneous abortion Diseases 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002936 tranquilizing effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/43—Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
- A61K36/638—Ligustrum, e.g. Chinese privet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/64—Orobanchaceae (Broom-rape family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/89—Cyperaceae (Sedge family)
- A61K36/8905—Cyperus (flatsedge)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The application provides a traditional Chinese medicine composition for improving polycystic ovary syndrome and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. A traditional Chinese medicine composition for improving polycystic ovary syndrome comprises the following raw materials in parts by weight: 8-20 parts of radix codonopsis pilosulae, 12-25 parts of radix astragali preparata, 8-20 parts of prepared rehmannia root, 8-20 parts of angelica, 8-20 parts of white paeony root, 8-20 parts of szechuan lovage rhizome, 12-30 parts of red sage root, 8-20 parts of semen cuscutae, 5-15 parts of morinda officinalis, 5-15 parts of epimedium herb, 5-15 parts of radix bupleuri, 8-20 parts of prepared nutgrass galingale rhizome, 8-20 parts of glossy privet fruit, 8-20 parts of eclipta, 5-15 parts of curculigo rhizome, 5-15 parts of cistanche, 8-20 parts of mistletoe and 8-20 parts of Chinese teasel root; it can effectively improve and treat polycystic ovary syndrome, and has the effects of tonifying kidney, strengthening spleen, promoting blood circulation and tonifying qi. The preparation method has simple flow, and the prepared medicine has good therapeutic effect and convenient use.
Description
Technical Field
The application relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving polycystic ovary syndrome and a preparation method thereof.
Background
Polycystic ovary syndrome (PCOS) is a complex disorder of endocrine and metabolic abnormalities common to women of childbearing age, characterized by chronic anovulation (anovulation dysfunction or loss) and hyperandrogenism (excessive production of male hormone in women), and is characterized by irregular menstrual cycles, infertility, hirsutism and/or acne, the most common female endocrine disorder. Clinically, symptoms such as menstrual disorder, obesity and the like can occur, high androgen related clinical manifestations such as hirsutism, alopecia and the like can also occur, infertility can be seriously caused, adverse effects can be brought to daily social life of a patient, and the physical health of the patient can be threatened, so that a medicine capable of improving polycystic ovary syndrome needs to be developed.
Disclosure of Invention
The application aims to provide a traditional Chinese medicine composition for improving polycystic ovary syndrome, which can effectively improve and treat polycystic ovary syndrome and has the effects of tonifying kidney and spleen, activating blood and tonifying qi.
The application also aims to provide a preparation method of the traditional Chinese medicine composition for improving polycystic ovary syndrome, which has the advantages of simple process flow, good treatment effect of the prepared medicine and convenient use.
The application solves the technical problems by adopting the following technical scheme.
In one aspect, the embodiment of the application provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which comprises the following raw materials in parts by weight: 8-20 parts of radix codonopsis pilosulae, 12-25 parts of radix astragali preparata, 8-20 parts of prepared rehmannia root, 8-20 parts of Chinese angelica, 8-20 parts of white paeony root, 8-20 parts of szechuan lovage rhizome, 12-30 parts of red sage root, 8-20 parts of semen cuscutae, 5-15 parts of morinda officinalis, 5-15 parts of epimedium, 5-15 parts of radix bupleuri, 8-20 parts of prepared nutgrass galingale rhizome, 8-20 parts of glossy privet fruit, 8-20 parts of eclipta, 5-15 parts of curculigo rhizome, 5-15 parts of cistanche, 8-20 parts of mistletoe and 8-20 parts of Chinese teasel root.
On the other hand, the embodiment of the application provides a preparation method of a traditional Chinese medicine composition for improving polycystic ovary syndrome, which comprises the following steps: respectively taking radix codonopsis pilosulae, radix astragali Preparata, radix rehmanniae Preparata, radix Angelicae sinensis, radix Paeoniae alba, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, semen Cuscutae, radix Morindae officinalis, herba Epimedii, bupleuri radix, rhizoma Cyperi preparata, fructus Ligustri Lucidi, ecliptae herba, rhizoma Curculiginis, cistanchis herba, herba Taxilli and radix Dipsaci, drying, pulverizing, sieving to obtain medicinal powder, decocting in water to obtain decoction, and making into final product.
Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:
aiming at the first aspect, the embodiment of the application provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which comprises the following raw materials in parts by weight: 8-20 parts of radix codonopsis pilosulae, 12-25 parts of radix astragali preparata, 8-20 parts of prepared rehmannia root, 8-20 parts of Chinese angelica, 8-20 parts of white paeony root, 8-20 parts of szechuan lovage rhizome, 12-30 parts of red sage root, 8-20 parts of semen cuscutae, 5-15 parts of morinda officinalis, 5-15 parts of epimedium, 5-15 parts of radix bupleuri, 8-20 parts of prepared nutgrass galingale rhizome, 8-20 parts of glossy privet fruit, 8-20 parts of eclipta, 5-15 parts of curculigo rhizome, 5-15 parts of cistanche, 8-20 parts of mistletoe and 8-20 parts of Chinese teasel root.
In the above embodiment, the efficacy of each raw medicinal material is as follows:
radix codonopsis pilosulae: strengthening spleen, tonifying lung, supplementing qi and promoting fluid production; deficiency of spleen and stomach, loose stool due to anorexia, debilitation of limbs, dyspnea and cough due to lung deficiency, shortness of breath and spontaneous perspiration, and slight deficiency of both qi.
Radix astragali Preparata: qi and middle-jiao tonifying; it is used for treating deficiency of qi, debilitation, anorexia, and loose stool.
Prepared rehmannia root: nourishing yin and replenishing blood, replenishing essence and replenishing marrow; can be used for treating deficiency of liver-yin and kidney-yin, soreness of waist and knees, hectic fever due to bone steaming, night sweat, spermatorrhea, internal heat, diabetes, blood deficiency, sallow complexion, palpitation, menoxenia, metrorrhagia, blood stasis, dizziness, tinnitus, and premature graying of hair and beard.
Chinese angelica root: replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation; can be used for treating sallow complexion due to blood deficiency, dizziness, palpitation, menoxenia, amenorrhea, dysmenorrhea, abdominal pain due to deficiency-cold, constipation due to intestinal dryness, rheumatalgia, traumatic injury, carbuncle, and pyocutaneous disease.
White peony root: pacify liver, relieve pain, nourish blood, regulate menstruation, astringe yin and stop sweat; can be used for treating headache, vertigo, hypochondriac pain, abdominal pain, limb spasm and pain, blood deficiency, sallow complexion, menoxenia, spontaneous perspiration, and night sweat.
Ligusticum wallichii: promoting blood circulation, removing blood stasis, promoting qi circulation, resolving stagnation, dispelling pathogenic wind and relieving pain; menoxenia, amenorrhea, dysmenorrhea, puerperal stasis and pain, lump in the abdomen, chest and hypochondrium pain, headache and dizziness, arthralgia due to wind-cold-dampness, traumatic injury, carbuncle and sore.
Root of red-rooted salvia: promoting blood circulation, removing blood stasis, regulating menstruation, relieving pain, nourishing blood, tranquillizing, cooling blood and resolving carbuncles; the women have irregular menstruation, dysmenorrhea, amenorrhea, postpartum abdominal stasis and pain, heart and abdomen pain, abdominal mass, heat arthralgia and swelling pain, traumatic injury, heat entering nutrient blood, dysphoria, vexation and insomnia, carbuncle, sore and pyogenic infections.
Semen cuscutae: nourishing liver and kidney, securing essence, reducing urination, preventing miscarriage, improving eyesight, and relieving diarrhea; can be used for treating sexual impotence, spermatorrhea, dribbling urine, enuresis, frequent urination, soreness of waist and knees, dizziness, tinnitus, kidney deficiency, fetal movement, and diarrhea due to spleen and kidney deficiency; it is used for treating vitiligo.
Radix Morindae officinalis: kidney tonifying, yang supporting, tendons and bones strengthening, wind dispelling and dampness eliminating; impotence due to deficiency of the kidney, spermatorrhea, premature ejaculation, cold pain in lower abdomen, urinary incontinence, infertility due to cold womb, arthralgia due to wind-cold-dampness, soreness of waist and knees, and rheumatic limb qi.
Epimedium herb: kidney-tonifying, yang-strengthening, wind-dispelling, dampness-removing, tendons and bones-strengthening; impotence, spermatorrhea, infertility due to deficiency-cold, frequent urination, cough and asthma due to deficiency of the kidney, soreness of the waist and knees, rheumatalgia, hemiplegia, and limb numbness.
Bupleurum root: relieving exterior syndrome and fever, soothing liver and relieving depression, and lifting yang qi; fever due to exogenous pathogenic factors, cold and heat going forward and backward, malaria, liver Yu Xie pain and distention, headache and dizziness, menoxenia, rectocele due to qi deficiency sinking, uterine prolapse, and gastroptosis.
Preparing nutgrass galingale rhizome: promoting qi circulation, resolving stagnation, regulating menstruation and relieving pain. Can be used for treating liver depression, qi stagnation, chest pain, hypochondrium pain, abdominal distention and pain, dyspepsia, chest distress, cold hernia abdominal pain, breast pain, menoxenia, amenorrhea and dysmenorrhea.
Fructus ligustri lucidi: tonify liver and kidney, clear deficiency heat, improve eyesight; dizziness, soreness and weakness of waist and knees, spermatorrhea, tinnitus, premature graying hair, hectic fever due to steaming bones, and dim eyesight.
Ecliptae herba: nourishing liver and kidney, cooling blood and stopping bleeding; can be used for treating odontoseisis, premature graying of hair, dizziness, tinnitus, soreness of waist and knees, yin deficiency, blood heat, hematemesis, epistaxis, hematuria, dysentery, metrorrhagia, hemorrhage, and traumatic hemorrhage.
Curculigo rhizome: kidney yang, strengthening tendons and bones, and dispelling cold dampness; can be used for treating sexual impotence, cold sperm, flaccidity of tendons and bones, cold arthralgia of waist and knee, and diarrhea due to yang deficiency.
Cistanche deserticola: kidney yang tonifying, essence and blood replenishing, and intestinal tract moistening; impotence due to deficiency of kidney-yang and deficiency of essence and blood, spermatorrhea, turbid urine, frequent urination, dribbling urine, lumbago, weakness of feet, tinnitus, blurred vision, menstrual period, infertility due to cold womb, constipation due to dryness of the intestines.
Loranthus mulberry mistletoe: liver and kidney tonifying, tendons and bones strengthening, wind-damp expelling, an Taiyuan. Can be used for treating rheumatalgia, soreness of waist and knees, weakness of tendons and bones, metrorrhagia, menorrhagia, blood leakage during pregnancy, and fetal irritability; hypertension.
Radix Dipsaci: liver and kidney tonifying, tendons and bones strengthening, fracture healing and metrorrhagia stopping; can be used for treating soreness of waist and knees, rheumatalgia, metrorrhagia, metrostaxis, and traumatic injury. Jiu xu is often used for wind-damp arthralgia and traumatic injury. Duan is commonly used for soreness and weakness of waist and knees.
The traditional Chinese medicine composition for improving polycystic ovary syndrome has the effects of invigorating spleen, tonifying lung, tonifying qi and strengthening middle-jiao by matching dangshen with radix astragali preparata; the prepared rehmannia root, the Chinese angelica, the white peony root, the szechuan lovage rhizome and the red sage root are matched to play roles of nourishing yin and supplementing blood, regulating menstruation and relieving pain and activating blood and removing stasis; the Chinese dodder seed and the morinda root, the epimedium herb, the curculigo rhizome, the cistanche, the mistletoe and the dipsacus root are matched with each other to play roles in nourishing liver and kidney, dispelling wind and removing dampness and strengthening tendons and bones, and the Chinese thorowax root, the prepared nutgrass galingale rhizome, the glossy privet fruit and the black lotus are matched with each other to play roles in relieving exterior syndrome and allaying fever, promoting qi circulation and relieving depression, and meanwhile, the effects of nourishing liver and kidney and regulating menstruation and relieving pain can be enhanced. The raw materials are combined and matched with each other to realize synergistic interaction, and the product medicament mainly has the effects of nourishing liver and kidney, promoting blood circulation and soothing liver, and also has the effects of strengthening spleen and tonifying qi, dispelling wind and removing dampness, regulating menstruation and relieving pain, so that the endocrine relief of a patient is effectively improved, the obesity, seborrhea and other symptoms of the patient are regulated, the physique of the patient is improved, the normal menstruation is helped to recover, ovulation is generated, infertility symptoms caused by polycystic ovary syndrome are prevented and treated, and the symptoms and root causes are treated, so that the Chinese medicinal composition has a good treatment effect.
Aiming at the second aspect, the embodiment of the application provides a preparation method of a traditional Chinese medicine composition for improving polycystic ovary syndrome, which comprises the steps of firstly drying and crushing codonopsis pilosula, radix astragali preparata, prepared rehmannia root, chinese angelica, white paeony root, szechuan lovage rhizome, red-rooted salvia root, chinese dodder seed, medicinal indianmulberry root, epimedium herb, chinese thorowax root, prepared nutgrass galingale rhizome, glossy privet fruit, eclipta, common curculigo rhizome, desertliving cistanche, mistletoe and Chinese teasel root, and sieving to obtain medicinal powder; the contact area between the medicinal materials and water is increased by crushing, so that the effective components contained in each raw medicinal material can be extracted more fully in the subsequent decoction operation, the medicinal effect is improved, and the medicine waste is reduced. Then adding water into the crushed medicinal powder for decoction to obtain decoction, and obtaining a finished product; the effective components in the raw medicinal materials are extracted by adding water for decoction, so that the respective beneficial effects of the raw medicinal materials can be fully exerted, and meanwhile, the medicinal materials can be better combined and matched with each other to realize synergistic effect, so that the effect of the product medicament is further improved. The whole preparation method has simple flow, and the prepared product medicine has the effects of nourishing liver and kidney, activating blood, soothing liver, strengthening spleen, tonifying qi, dispelling wind, removing dampness, regulating menstruation and relieving pain, can effectively improve and treat polycystic ovary syndrome and related symptoms caused by polycystic ovary syndrome, and has good treatment effect and convenient use.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.
It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The present application will be described in detail with reference to specific examples.
The embodiment provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which comprises the following raw materials in parts by weight: 8-20 parts of radix codonopsis pilosulae, 12-25 parts of radix astragali preparata, 8-20 parts of prepared rehmannia root, 8-20 parts of Chinese angelica, 8-20 parts of white paeony root, 8-20 parts of szechuan lovage rhizome, 12-30 parts of red sage root, 8-20 parts of semen cuscutae, 5-15 parts of morinda officinalis, 5-15 parts of epimedium, 5-15 parts of radix bupleuri, 8-20 parts of prepared nutgrass galingale rhizome, 8-20 parts of glossy privet fruit, 8-20 parts of eclipta, 5-15 parts of curculigo rhizome, 5-15 parts of cistanche, 8-20 parts of mistletoe and 8-20 parts of Chinese teasel root.
In the embodiment, the radix codonopsis pilosulae and the radix astragali preparata are matched, so that the effects of strengthening the spleen, tonifying the lung, tonifying qi and strengthening the middle warmer are achieved; the prepared rehmannia root, the Chinese angelica, the white peony root, the szechuan lovage rhizome and the red sage root are matched to play roles of nourishing yin and supplementing blood, regulating menstruation and relieving pain and activating blood and removing stasis; the Chinese dodder seed and the morinda root, the epimedium herb, the curculigo rhizome, the cistanche, the mistletoe and the dipsacus root are matched with each other to play roles in nourishing liver and kidney, dispelling wind and removing dampness and strengthening tendons and bones, and the Chinese thorowax root, the prepared nutgrass galingale rhizome, the glossy privet fruit and the black lotus are matched with each other to play roles in relieving exterior syndrome and allaying fever, promoting qi circulation and relieving depression, and meanwhile, the effects of nourishing liver and kidney and regulating menstruation and relieving pain can be enhanced. The raw materials are combined and matched with each other to realize synergistic interaction, and the product medicament mainly has the effects of nourishing liver and kidney, promoting blood circulation and soothing liver, and also has the effects of strengthening spleen and tonifying qi, dispelling wind and removing dampness, regulating menstruation and relieving pain, so that the endocrine relief of a patient is effectively improved, the obesity, seborrhea and other symptoms of the patient are regulated, the physique of the patient is improved, the normal menstruation is helped to recover, ovulation is generated, infertility symptoms caused by polycystic ovary syndrome are prevented and treated, and the symptoms and root causes are treated, so that the Chinese medicinal composition has a good treatment effect.
Further, in some embodiments of the present application, the amounts of the raw materials in parts by weight are respectively: 15 parts of radix codonopsis pilosulae, 20 parts of radix astragali preparata, 15 parts of prepared rehmannia root, 15 parts of angelica sinensis, 15 parts of white paeony root, 15 parts of szechuan lovage rhizome, 20 parts of red sage root, 15 parts of dodder seed, 10 parts of morinda officinalis, 10 parts of epimedium, 10 parts of radix bupleuri, 15 parts of prepared nutgrass galingale rhizome, 15 parts of glossy privet fruit, 15 parts of eclipta, 10 parts of curculigo rhizome, 10 parts of cistanche deserticola, 15 parts of mistletoe and 15 parts of dipsacus root.
In the above embodiment, the dosage proportion of each raw material medicine is further limited, so that the medicine formula is more reasonable, the raw material medicines can be better combined and matched with each other, the synergy is achieved, the application range is wider, and the treatment and the use are more facilitated.
Further, in some embodiments of the present application, the formulation of the above-mentioned Chinese medicinal composition is a decoction.
In the embodiment, the decoction has the advantages of quick absorption and strong action, and the medicines can mutually promote and restrict each other, so that the purposes of enhancing the curative effect and relieving the medicine property are achieved, the compatibility of the medicines in the prescription can be fully exerted, the preparation process is simple, the use is convenient and quick, and the treatment and the use are facilitated.
The embodiment of the application also provides a preparation method of the traditional Chinese medicine composition for improving polycystic ovary syndrome, which comprises the following steps: respectively taking radix codonopsis pilosulae, radix astragali Preparata, radix rehmanniae Preparata, radix Angelicae sinensis, radix Paeoniae alba, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, semen Cuscutae, radix Morindae officinalis, herba Epimedii, bupleuri radix, rhizoma Cyperi preparata, fructus Ligustri Lucidi, ecliptae herba, rhizoma Curculiginis, cistanchis herba, herba Taxilli and radix Dipsaci, drying, pulverizing, sieving to obtain medicinal powder, decocting in water to obtain decoction, and making into final product.
In the above embodiment, radix Codonopsis, radix astragali Preparata, radix rehmanniae Preparata, radix Angelicae sinensis, radix Paeoniae alba, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, semen Cuscutae, radix Morindae officinalis, herba Epimedii, bupleuri radix, rhizoma Cyperi preparata, fructus Ligustri Lucidi, ecliptae herba, rhizoma Curculiginis, cistanchis herba, herba Taxilli and radix Dipsaci by drying, pulverizing, and sieving to obtain medicinal powder; the contact area between the medicinal materials and water is increased by crushing, so that the effective components contained in each raw medicinal material can be extracted more fully in the subsequent decoction operation, the medicinal effect is improved, and the medicine waste is reduced. Then adding water into the crushed medicinal powder for decoction to obtain decoction, and obtaining a finished product; the effective components in the raw medicinal materials are extracted by adding water for decoction, so that the respective beneficial effects of the raw medicinal materials can be fully exerted, and meanwhile, the medicinal materials can be better combined and matched with each other to realize synergistic effect, so that the effect of the product medicament is further improved. The whole preparation method has simple flow, and the prepared product medicine has the effects of nourishing liver and kidney, activating blood, soothing liver, strengthening spleen, tonifying qi, dispelling wind, removing dampness, regulating menstruation and relieving pain, can effectively improve and treat polycystic ovary syndrome and related symptoms caused by polycystic ovary syndrome, and has good treatment effect and convenient use.
Further, in some embodiments of the application, the mesh size of the screen is 80-150 mesh.
In the above embodiment, by pulverizing and sieving the raw medicinal materials, the effective components contained in each raw medicinal material can be sufficiently extracted in the subsequent decocting operation, which is beneficial to further improving the efficacy of the product.
Further, in some embodiments of the application, after comminution sieving, further micronization is performed and sieving through a 300 mesh sieve.
In the above embodiment, by further performing superfine grinding on the raw medicinal materials, the wall of the medicinal materials can be broken, so that the effective components contained in each raw medicinal material are fully exposed, thereby enhancing the extraction efficiency of the decoction and extraction of the medicament, enhancing the medicament effect, reducing the medicament waste, and being more beneficial to treatment, production and use.
Further, in some embodiments of the present application, water is added in an amount of 6 to 10 times the weight of the raw materials for 40 to 60 minutes.
In the embodiment, the dosage of water and the decoction time are controlled, so that the decoction and extraction efficiency of medicinal materials is improved, and the production and preparation are facilitated.
Further, in some embodiments of the present application, the water-decocting is repeated 2 times, the first time of water-decocting is performed for 40-60min by adding 6-10 times of the weight of the raw material, the second time of water-decocting is performed for 20-30min by adding 5-8 times of the weight of the raw material, and the filtrates are filtered and combined to obtain the decoction.
In the above embodiment, the amount of water added and the time of decoction are controlled by two times of decoction, which is helpful for more fully extracting the effective components contained in the raw medicinal materials, thereby further improving the efficacy of the product and enhancing the therapeutic effect of the medicament.
Further, in some embodiments of the present application, the method further comprises the steps of: concentrating the decoction to relative density of 1.15-1.20 at 40deg.C.
In the above embodiment, by concentrating the decoction, the excessive moisture can be removed, the concentration of the drug can be improved, the dosage of the drug can be reduced, the use experience of the drug can be improved while the drug effect is improved, and the treatment and the use are more facilitated.
Further, in some embodiments of the present application, the method further comprises the steps of: standing the decoction at 5-15deg.C for 6-12 hr, and filtering.
In the above embodiment, by standing and filtering the decoction at a low temperature, some drug precipitation residues contained in the decoction can be removed, so that the use experience of the product drug is improved, and the quality of the product drug is enhanced.
The features and capabilities of the present application are described in further detail below in connection with the examples.
Example 1
The embodiment provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which is prepared by the following method:
respectively taking 8g of codonopsis pilosula, 15g of radix astragali preparata, 10g of prepared rehmannia root, 10g of angelica, 8g of white paeony root, 8g of szechuan lovage rhizome, 15g of red-rooted salvia root, 10g of Chinese dodder seed, 10g of morinda root, 8g of epimedium herb, 8g of Chinese thorowax root, 10g of prepared nutgrass galingale rhizome, 15g of glossy privet fruit, 10g of eclipta, 5g of curculigo rhizome, 5g of cistanche, 8g of Chinese taxillus twig and 10g of Chinese teasel root, drying, crushing and sieving with a 80-mesh sieve to obtain medicinal powder, adding water with the weight of 8 times of the raw medicinal materials into the medicinal powder, decocting for 45min to obtain decoction, concentrating the decoction to the relative density of 1.15 at 40 ℃, standing for 12h at the temperature of 10 ℃, and filtering to obtain the finished product.
Example 2
The embodiment provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which is prepared by the following method:
respectively taking 15g of codonopsis pilosula, 18g of radix astragali preparata, 10g of prepared rehmannia root, 15g of angelica, 10g of white paeony root, 10g of szechuan lovage rhizome, 20g of red-rooted salvia root, 15g of Chinese dodder seed, 10g of morinda root, 12g of epimedium herb, 10g of Chinese thorowax root, 1g of prepared nutgrass galingale rhizome, 15g of glossy privet fruit, 15g of eclipta, 8g of common curculigo rhizome, 8g of cistanche, 12g of Chinese taxillus twig and 12g of Chinese teasel root, drying, crushing and sieving with a 100-mesh sieve to obtain medicinal powder, repeatedly adding water into the medicinal powder for 2 times, adding water with the weight of 8 times of the medicinal material for 60min, adding water with the weight of 5 times of the medicinal material for 30min for the second time, filtering and merging the filtrate to obtain decoction, concentrating the decoction to the relative density of 1.15 at 40 ℃, standing for 10h at 5 ℃ and filtering to obtain a finished product.
Example 3
The embodiment provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which is prepared by the following method:
respectively taking 18g of codonopsis pilosula, 22g of radix astragali preparata, 12g of prepared rehmannia root, 12g of angelica sinensis, 12g of white paeony root, 12g of ligusticum wallichii, 18g of red-rooted salvia root, 12g of semen cuscutae, 10g of morinda officinalis, 10g of epimedium herb, 10g of radix bupleuri, 12g of prepared nutgrass galingale rhizome, 16g of glossy privet fruit, 12g of eclipta, 8g of rhizoma curculiginis, 10g of cistanche, 10g of mistletoe and 12g of radix dipsaci, drying, crushing and sieving with a 150-mesh sieve to obtain medicinal powder, repeatedly adding water into the medicinal powder for 2 times, adding water with the weight of 10 times of the medicinal powder for decocting for 60min for the first time, adding water with the weight of 6 times of the medicinal powder for 30min for the second time, filtering and merging the filtrate to obtain decoction, concentrating the decoction to the relative density of 1.20 at 40 ℃, standing for 10h at 5 ℃ and filtering to obtain a finished product.
Example 4
The embodiment provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which is prepared by the following method:
respectively taking 18g of codonopsis pilosula, 22g of radix astragali preparata, 15g of prepared rehmannia root, 15g of Chinese angelica, 15g of white paeony root, 15g of szechuan lovage rhizome, 15g of red-rooted salvia root, 15g of Chinese dodder seed, 15g of morinda root, 12g of epimedium herb, 12g of Chinese thorowax root, 18g of prepared nutgrass galingale rhizome, 18g of glossy privet fruit, 15g of eclipta, 12g of common curculigo rhizome, 10g of desertliving cistanche, 12g of Chinese taxillus twig and 12g of Chinese teasel root, drying, crushing, sieving with a 80-mesh sieve, further superfine crushing, sieving with a 300-mesh sieve to obtain medicinal powder, repeatedly adding water into the medicinal powder for decoction for 2 times, adding water with the weight of 10 times of the raw medicinal material for 60min for the first time, adding water with the weight of 6 times of the raw material for the second time for decoction for 20min, filtering and merging the filtrate to obtain decoction, concentrating the decoction to the relative density of 1.15 at 40 ℃, standing for 12h at 5 ℃ and filtering to obtain a finished product.
Example 5
The embodiment provides a traditional Chinese medicine composition for improving polycystic ovary syndrome, which is prepared by the following method:
respectively taking 15g of codonopsis pilosula, 20g of radix astragali preparata, 15g of prepared rehmannia root, 15g of Chinese angelica, 15g of white paeony root, 15g of szechuan lovage rhizome, 20g of red-rooted salvia root, 15g of Chinese dodder seed, 10g of morinda root, 10g of epimedium herb, 10g of Chinese thorowax root, 15g of prepared nutgrass galingale rhizome, 15g of glossy privet fruit, 15g of eclipta, 10g of common curculigo rhizome, 10g of desertliving cistanche, 15g of Chinese taxillus twig and 15g of Chinese teasel root, drying, crushing, sieving with a sieve of 80-150 meshes, further superfine crushing, sieving with a sieve of 300 meshes to obtain medicinal powder, repeatedly adding water into the medicinal powder for decoction for 2 times, adding water with the weight of 10 times of the raw medicinal material for 60min for the first time, adding water with the weight of 6 times of the raw material for the second time for decoction for 20min, filtering and merging the filtrate to obtain decoction, concentrating the decoction to be 1.15 of relative density at 40 ℃, standing for 12h at 5 ℃ and filtering to obtain a finished product.
Test examples
31 polycystic ovary syndrome patients with the age of 25-35 years are treated continuously for 30-45 days by using the traditional Chinese medicine composition for improving polycystic ovary syndrome provided by the embodiment 5 of the application, and the treatment conditions of the patients are diagnosed and observed.
Patient inclusion criteria: meets the PCOS diagnosis standard and meets the requirement of age; hormone drugs are not taken within 30 days; has no other serious diseases and chronic diseases; the traditional Chinese medicine composition has no serious mental diseases and can be actively matched for treatment; informed and voluntarily receives the treatment.
Curative effect judgment criteria:
the method is effective: the symptoms related to high androgens disappear, and the menstruation is restored to normal;
the effect is shown: the symptoms related to high androgens are obviously improved and controlled, and the menstrual condition is obviously improved;
invalidation: the symptoms were not improved or were not significantly improved compared to pre-treatment.
The results show that the 31 polycystic ovary syndrome patients are cured by 18, 11 and 2 cases of effective and ineffective, no accident occurs, and the treatment effect is obvious, safe and effective.
The following are some typical cases:
zhu Mou female, 32 years old, menoxenia, menstrual period or before or after, obesity, acne on the face, soreness of the waist and knees, and polycystic ovary syndrome; the traditional Chinese medicine composition for improving polycystic ovary syndrome provided by the application is used for obviously controlling facial acne after continuous treatment for 30 days, recovering menstruation to be normal, and has the advantages of no recurrence after 6 months of follow-up after treatment, obvious improvement of obesity type and obvious treatment effect.
Wu Mou female, 28 years old, menstrual disorder, alopecia symptoms, lower limb trichomadesis, occasional vertigo symptoms, diagnosis of polycystic ovary syndrome; the traditional Chinese medicine composition for improving polycystic ovary syndrome provided by the application is used for obviously controlling alopecia after continuous treatment for 30 days, restoring menstrual flow to be normal, and has obvious treatment effect after 6 months of return visit without recurrence.
Liu Mou female, 27 years old, menstrual disorder, hypomenorrhea, chest body hair increase, arm body hair aggravation, acne on the face, diagnosis of polycystic ovary syndrome; the traditional Chinese medicine composition for improving polycystic ovary syndrome provided by the application is used for obviously controlling facial acne and hair symptoms after continuous treatment for 30 days, and has the advantages of normal menstrual recovery, no recurrence after 6 months of follow-up after treatment and obvious treatment effect.
In summary, the traditional Chinese medicine composition for improving polycystic ovary syndrome and the preparation method thereof provided by the embodiment of the application have the effects of nourishing liver and kidney, dispelling wind and removing dampness and strengthening tendons and bones by matching the traditional Chinese medicine composition with the dodder seed, the morinda officinalis, the epimedium herb, the curculigo rhizome, the cistanche salsa, the mistletoe and the teasel root, and have the effects of relieving exterior syndrome and allaying fever, promoting qi circulation and resolving depression by matching the bupleurum root, the prepared nutgrass galingale rhizome, the glossy privet fruit and the jezoma coptidis. The raw materials are combined and matched with each other to realize synergistic interaction, and the product medicament mainly has the effects of nourishing liver and kidney, promoting blood circulation and soothing liver, and also has the effects of strengthening spleen and tonifying qi, dispelling wind and removing dampness, regulating menstruation and relieving pain, so that the endocrine relief of a patient is effectively improved, the obesity, seborrhea and other symptoms of the patient are regulated, the physique of the patient is improved, the normal menstruation is helped to recover, ovulation is generated, infertility symptoms caused by polycystic ovary syndrome are prevented and treated, and both symptoms and root causes are treated, so that the product medicament has a good treatment effect; the preparation method comprises the steps of firstly, drying, crushing and sieving the raw medicinal materials to obtain medicinal powder; the contact area between the medicinal materials and water is increased by crushing, so that the effective components contained in each raw medicinal material can be extracted more fully in the subsequent decoction operation, the medicinal effect is improved, and the medicine waste is reduced. Then adding water into the crushed medicinal powder for decoction to obtain decoction, and obtaining a finished product; the effective components in the raw medicinal materials are extracted by adding water for decoction, so that the respective beneficial effects of the raw medicinal materials can be fully exerted, and meanwhile, the medicinal materials can be better combined and matched with each other to realize synergistic effect, so that the effect of the product medicament is further improved. The whole preparation method has simple flow, and the prepared product medicine has the effects of nourishing liver and kidney, activating blood, soothing liver, strengthening spleen, tonifying qi, dispelling wind, removing dampness, regulating menstruation and relieving pain, can effectively improve and treat polycystic ovary syndrome and related symptoms caused by polycystic ovary syndrome, and has good treatment effect and convenient use.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
Claims (10)
1. The traditional Chinese medicine composition for improving polycystic ovary syndrome is characterized by comprising the following raw materials in parts by weight: 8-20 parts of radix codonopsis pilosulae, 12-25 parts of radix astragali preparata, 8-20 parts of prepared rehmannia root, 8-20 parts of Chinese angelica, 8-20 parts of white paeony root, 8-20 parts of szechuan lovage rhizome, 12-30 parts of red sage root, 8-20 parts of semen cuscutae, 5-15 parts of morinda officinalis, 5-15 parts of epimedium, 5-15 parts of radix bupleuri, 8-20 parts of prepared nutgrass galingale rhizome, 8-20 parts of glossy privet fruit, 8-20 parts of eclipta, 5-15 parts of curculigo rhizome, 5-15 parts of cistanche, 8-20 parts of mistletoe and 8-20 parts of Chinese teasel root.
2. The traditional Chinese medicine composition for improving polycystic ovary syndrome according to claim 1, wherein the raw materials are respectively used in parts by weight: 15 parts of radix codonopsis pilosulae, 20 parts of radix astragali preparata, 15 parts of prepared rehmannia root, 15 parts of angelica sinensis, 15 parts of white paeony root, 15 parts of szechuan lovage rhizome, 20 parts of red sage root, 15 parts of dodder seed, 10 parts of morinda officinalis, 10 parts of epimedium, 10 parts of radix bupleuri, 15 parts of prepared nutgrass galingale rhizome, 15 parts of glossy privet fruit, 15 parts of eclipta, 10 parts of curculigo rhizome, 10 parts of cistanche deserticola, 15 parts of mistletoe and 15 parts of dipsacus root.
3. The traditional Chinese medicine composition for improving polycystic ovary syndrome according to claim 1, wherein the traditional Chinese medicine composition is in a form of decoction.
4. A method for preparing a traditional Chinese medicine composition for improving polycystic ovary syndrome according to any one of claims 1-3, comprising the steps of: respectively taking radix codonopsis pilosulae, radix astragali Preparata, radix rehmanniae Preparata, radix Angelicae sinensis, radix Paeoniae alba, rhizoma Ligustici Chuanxiong, saviae Miltiorrhizae radix, semen Cuscutae, radix Morindae officinalis, herba Epimedii, bupleuri radix, rhizoma Cyperi preparata, fructus Ligustri Lucidi, ecliptae herba, rhizoma Curculiginis, cistanchis herba, herba Taxilli and radix Dipsaci, drying, pulverizing, sieving to obtain medicinal powder, decocting in water to obtain decoction, and making into final product.
5. The method for preparing a Chinese medicinal composition for improving polycystic ovary syndrome according to claim 4, wherein the mesh number of the sieve is 80-150 mesh.
6. The method for preparing a Chinese medicinal composition for improving polycystic ovary syndrome according to claim 4, wherein after pulverizing and sieving, further micronizing and sieving with 300 mesh sieve.
7. The method for preparing a Chinese medicinal composition for improving polycystic ovary syndrome according to claim 4, wherein the water is added in an amount of 6-10 times the weight of the raw materials and the mixture is decocted for 40-60min.
8. The method for preparing a Chinese medicinal composition for improving polycystic ovary syndrome according to claim 4, wherein the steps of repeatedly adding water and decocting for 2 times, adding water and decocting for 40-60min by 6-10 times of the weight of the raw medicinal materials for the first time, adding water and decocting for 20-30min by 5-8 times of the weight of the raw medicinal materials for the second time, filtering and combining the filtrates to obtain a decoction.
9. The method for preparing a traditional Chinese medicine composition for improving polycystic ovary syndrome according to claim 4, further comprising the steps of: concentrating the decoction to relative density of 1.15-1.20 at 40deg.C.
10. The method for preparing a traditional Chinese medicine composition for improving polycystic ovary syndrome according to claim 4, further comprising the steps of: standing the decoction at 5-15deg.C for 6-12 hr, and filtering.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210587950.3A CN114886983B (en) | 2022-05-27 | 2022-05-27 | Traditional Chinese medicine composition for improving polycystic ovarian syndrome and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210587950.3A CN114886983B (en) | 2022-05-27 | 2022-05-27 | Traditional Chinese medicine composition for improving polycystic ovarian syndrome and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114886983A CN114886983A (en) | 2022-08-12 |
| CN114886983B true CN114886983B (en) | 2023-09-19 |
Family
ID=82726511
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210587950.3A Active CN114886983B (en) | 2022-05-27 | 2022-05-27 | Traditional Chinese medicine composition for improving polycystic ovarian syndrome and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114886983B (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816617A (en) * | 2016-04-29 | 2016-08-03 | 山东省立医院 | Traditional Chinese medicine composition for treating obesity type polycystic ovarian syndrome |
-
2022
- 2022-05-27 CN CN202210587950.3A patent/CN114886983B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105816617A (en) * | 2016-04-29 | 2016-08-03 | 山东省立医院 | Traditional Chinese medicine composition for treating obesity type polycystic ovarian syndrome |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114886983A (en) | 2022-08-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN106075276A (en) | A kind of for Chinese medicine preparation treating threatened abortion and preparation method thereof | |
| CN113318172A (en) | Traditional Chinese medicine composition for treating ovarian reserve function decline combined infertility and preparation method and application thereof | |
| CN104208554A (en) | Traditional Chinese medicine mainly for treating multiple female diseases | |
| CN105664099A (en) | Traditional Chinese medicine composition for warming and invigorating kidney yang and preparation method thereof | |
| CN104225215A (en) | Traditional Chinese medicine for treating insomnia | |
| CN103142895B (en) | Kidney nourishing mixture and preparation method thereof | |
| CN111298085A (en) | Traditional Chinese medicine composition for benefiting qi, nourishing blood, clearing and activating channels and collaterals and preparation method thereof | |
| CN103301391A (en) | Traditional Chinese medicine for treating female infertility and preparation method thereof | |
| CN105194338A (en) | Traditional Chinese medicine composition for treating uterus cold and preparation method thereof | |
| CN114886983B (en) | Traditional Chinese medicine composition for improving polycystic ovarian syndrome and preparation method thereof | |
| CN101703619A (en) | Chinese medicament for treating hyperosteogeny and osteoarthritis | |
| CN106361918A (en) | Traditional Chinese medicine patch for treating deficiency of kidney-yang | |
| CN105362827A (en) | Decoction capable of effectively treating anemia and preparation method thereof | |
| CN105560842A (en) | Traditional Chinese medicine preparation for treating leucoderma caused by liver and kidney deficiency and wind-damp collateral blockage | |
| CN105456878A (en) | Method for preparing traditional Chinese medicine composition for treating impotence and premature ejaculation and reinforcing kidney to strengthen yang | |
| CN111265609A (en) | Traditional Chinese medicine composition for adjuvant treatment of true myopia and preparation method thereof | |
| CN104958722A (en) | Dampness removing and arthralgia dispelling wine | |
| CN103656460A (en) | Traditional Chinese medicinal composition for treating diabetes | |
| CN104257813B (en) | A kind of Chinese medicine composition of QI and blood regulating and preparation method thereof | |
| CN101912476A (en) | Chinese medicinal herbs for treating female menorrhagia disease | |
| CN110090271B (en) | Traditional Chinese medicine composition for treating male infertility, preparation and application thereof | |
| CN106389991A (en) | Navel treatment drug composition for andrology diseases as well as preparation method and application of navel treatment drug composition | |
| CN106310024A (en) | Chinese herb preparation for treating menstruation delay and preparation method | |
| CN104998241A (en) | Astragalus membranaceus qi-tonifying traditional Chinese medicine liquor | |
| CN105250820A (en) | Medicine used for treating vitiligo |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |