CN101703619A - Chinese medicament for treating hyperosteogeny and osteoarthritis - Google Patents

Abstract

The invention discloses a Chinese medicament, in particular to a Chinese medicament for treating hyperosteogeny and osteoarthritis, which is prepared from himalayan teasel root, dried radix rehmanniae, common macrocarpium fruit, twotooth achyranthes root, radix astragali, szechuan lovage rhizome, Chinese angelica, Chinese alangium root, cortex acanthopanax bark, Chinese lizardtail rhizome or herb, Chinese honeylocust spine, mulberry twig, honeysuckle flower, figwort root, silvervine twig and leaf, pittosporm root, forbes notopterygium rhizome and liquoric root in certain weight proportion. The Chinese medicament has simple preparation, good absorption effect, obvious curative effect, no toxic or side effect and high safety.

Description

The Chinese medicine of treatment hyperosteogeny, osteoarthritis

(1) technical field

The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine for the treatment of hyperosteogeny, osteoarthritis.

(2) background technology

Hyperosteogeny is because the cartilage in joint is degenerated gradually, and the elasticity of cell reduces, osteoarthrosis wearing and tearing, the especially neck that activity is bigger, waist, knee joint, heel.The articular cartilage of damage is difficult to repair when not having blood vessel to supply with nutrition, and at this moment the peripheral blood recycle ratio in articular cartilage is more vigorous, the compensatory cartilage growth will occur, this is the predecessor of hyperosteogeny, and is of long duration, outgrowth cartilage is by calcification, and hyperosteogeny that Here it is also is bony spur.Bony spur is generally asymptomatic, need not treatment, can just be transformed into pathological state in case symptom occur, but teratogenesis or cause paralysis when serious.

Osteoarthritis is a kind of common articular cartilage disease that involves each joint of whole body, and the prevalence in China's mid-aged population reaches 4%.Along with China's aged tendency of population, the osteoarthritis sickness rate increases thereupon, and useless damage the in osteoarthritis patient joint in whole latter stage sexually revises, and causes serious joint function disturbance, be the main cause of middle-aged and elderly people physical disabilities, have only the expensive joint replacement surgery of acceptance could remove patient's misery.

In the present Therapeutic Method, doctor trained in Western medicine adopts usually and takes the Therapeutic Method of pain relieving, analgesic and operation, and its result not only index is not effected a permanent cure, and has toxic and side effects; Methods such as the acupuncture that the traditional Chinese medical science usually adopts, physical therapy, small needle knife, massage, treatment cycle is grown, is taken effect slowly, symptom has improvement, the problem that can't fundamentally cure though all exist.

(3) summary of the invention

The present invention provides a kind of good effect, instant effect, the treatment hyperosteogeny that is difficult for recurrence, the Chinese medicine of osteoarthritis in order to remedy the deficiencies in the prior art.

The present invention is achieved through the following technical solutions:

A kind of Chinese medicine for the treatment of hyperosteogeny, osteoarthritis, its special character is: the raw material by following parts by weight is formed:

6～12 parts of Radix Dipsacis, 9～15 parts of Radix Rehmanniaes, 6～10 parts of Fructus Corni, 6～12 parts of Radix Achyranthis Bidentataes, 9～15 parts of the Radixs Astragali, 3～9 parts of Rhizoma Chuanxiongs, 6～12 parts of Radix Angelicae Sinensis, 1～3 part of Radix Alangii, 4～8 parts of Cortex Acanthopanciss, 9～15 parts of Rhizoma Saururi (Herba Saururi)s, 3～9 parts of Spina Gleditsiaes, 12～18 parts of Ramulus Moris, 9～15 parts of Flos Loniceraes, 9～15 parts of Radix Scrophulariaes, 3～9 parts of Ramulus et Folium Actinidiae Polygamaes, 12～18 parts of pittosporm root, 3～9 parts of Rhizoma Et Radix Notopterygiis, 6～10 parts in Radix Glycyrrhizae.

Its preferred proportioning raw materials is:

9 parts of Radix Dipsacis, 12 parts of Radix Rehmanniaes, 8 parts of Fructus Corni, 9 parts of Radix Achyranthis Bidentataes, 12 parts of the Radixs Astragali, 6 parts of Rhizoma Chuanxiongs, 9 parts of Radix Angelicae Sinensis, 2 parts of Radix Alangiis, 6 parts of Cortex Acanthopanciss, 12 parts of Rhizoma Saururi (Herba Saururi)s, 6 parts of Spina Gleditsiaes, 15 parts of Ramulus Moris, 12 parts of Flos Loniceraes, 12 parts of Radix Scrophulariaes, 6 parts of Ramulus et Folium Actinidiae Polygamaes, 15 parts of pittosporm root, 6 parts of Rhizoma Et Radix Notopterygiis, 8 parts in Radix Glycyrrhizae.

Chinese medicine of the present invention is powder.After various raw materials are cleaned up, place water to boil to paste, again that raw material is air-dry, pulverize is quantitatively taken behind the mix homogeneously.Boiling helps medicament curative effect enhancement in water, reduces the toxic and side effects of medicine.

Pharmaceutical characteristic to each raw material briefly introduces below:

Radix Dipsaci: invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating ends metrorrhagia. and cure mainly aching pain in waist and back, the podomere flaccidity syndrome and arthralgia syndrome falls and pounces on wound, decreases muscle folding bone, and fetal movement is leaked red, metrorrhagia, seminal emission, leukorrhagia, the carbuncle skin ulcer is swollen;

Radix Rehmanniae: have another name called Radix Rehmanniae, clearing away heat from blood, easy cloudy blood, promoting blood circulation.Cure mainly epidemic febrile disease heating, haematemesis, epistaxis, metrorrhagia, the hematuria due to the jaundice, heat in blood, have blood in stool, quench one's thirst hectic fever due to YIN-deficiency consumptive fever, amenorrhea, puerperal abdonimal pain, numbness flaccidity, traumatic injury;

Fructus Corni: liver and kidney tonifying, convergence is taken off admittedly.Cure mainly and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding;

Radix Achyranthis Bidentatae: invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, it is descending to draw blood (fire), inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood is stimulated the menstrual flow, puerperal abdominal pain due to blood stasis ， mass in the abdomen, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain;

The Radix Astragali: benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, promoting pus discharge and tissue regeneration strengthening.Cure mainly the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back;

Rhizoma Chuanxiong: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.Cure mainly menoxenia, the amenorrhea dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， mass in the abdomen lump, pain in chest and hypochondrium, it is dizzy to have a headache, anemofrigid-damp arthralgia, traumatic injury, ulcer sores;

Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving is moisturized laxation.Cure mainly all diseases of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down;

Radix Alangii: expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, eliminating stasis to stop pain.Cure mainly rheumatic arthralgia, paralysis, the arthroncus of knee, innominate toxic swelling, traumatic injury;

Cortex Acanthopancis: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, the arteries and veins of invigorating blood circulation.Cure mainly anemofrigid-damp arthralgia, lumbocrural pain, the muscles and bones flaccidity is soft, children's's walking retardation in children, a little less than the body weakness with emaciation, traumatic injury, fracture, edema, beriberi, uncontrolled urination is itched;

Rhizoma Saururi (Herba Saururi): heat-clearing and toxic substances removing, inducing diuresis to remove edema.Cure mainly pyretic stranguria, stranguria with blood, edema, beriberi, jaundice, dysentery, leukorrhagia, carbuncle sore tumefacting virus, eczema, venom;

Spina Gleditsiae: the pus of subsiding a swelling, search wind, parasite killing.Cure mainly swollen ulcer drug, scrofula, leprosy, skin ulcer rash stubborn dermatitis, puerperal hypogalactia, placenta retention;

Ramulus Mori: wind-damp dispelling, the meridian dredging, row aqueous vapor.Cure mainly rheumatic arthralgia, apoplexy and hemiplegia, edema beriberi, human body pruritus due to wind pathogen;

Flos Lonicerae: heat-clearing and toxic substances removing.Cure mainly the heating of affection due to external wind and heat or epidemic febrile disease, heatstroke, toxic-heat and blood stasis, carbuncle furuncle, sore throat, multiple infectious disease;

Radix Scrophulariae: removing heat from blood, nourishing YIN to lower pathogenic fire, detoxifcation.Cure mainly the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, scrofula sucutaneous nodule, skin sore;

Ramulus et Folium Actinidiae Polygamae: wind-damp dispelling ， Xiao mass in the abdomen, the meridian dredging, tonifying deficiency.Cure mainly apoplexy and hemiplegia, anemofrigid-damp arthralgia, pain in the lumbar region, colic ， lumps in the chest and abdomen, wind labor cold caused by deficiency, diarrhea due to disorder of qi, vitiligo;

Pittosporm root: activating collaterals to relieve pain, heart-calming kidney-nourishing, detoxifcation.Cure mainly rheumatic arthralgia, fracture, stomachache, insomnia, seminal emission, venom;

Rhizoma Et Radix Notopterygii: separate exterior cold, wind-damp dispelling, sharp joint, pain relieving.Cure mainly affection of exogenous wind-cold, it is lossless to have a headache, anemofrigid-damp arthralgia, edema due to wind pathogen edema, sore swollen toxin;

Radix Glycyrrhizae: property is flat, sweet in the mouth.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, nourishing the lung to arrest cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen and extremity contraction, carbuncle sore tumefacting virus, but the toxicity of cushion, strong.

In the prescription, Rhizoma Saururi (Herba Saururi), Spina Gleditsiae, Flos Lonicerae, Radix Scrophulariae are mainly used in heat-clearing and toxic substances removing, inducing diuresis to remove edema, nourishing YIN to lower pathogenic fire, eliminate the osteoarthrosis inflammation; Add and join that Cortex Acanthopancis, Ramulus Mori, Ramulus et Folium Actinidiae Polygamae, Rhizoma Et Radix Notopterygii, Radix Alangii are mainly used in expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, the cold expelling that induces sweat, eliminating stasis to stop pain, eliminate osteoarthrosis rheumatoid disease symptom; Join the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae again and be mainly used in benefiting qi and raising yang, blood circulation promoting and blood stasis dispelling, the osteoarthrosis wound is repaired; Join Radix Dipsaci, Fructus Corni, Radix Achyranthis Bidentatae, pittosporm root again and be mainly used in invigorating the liver and kidney, bone and muscle strengthening, fundamentally repair organ, reach healthy purpose, add at last and use Radix Glycyrrhizae, be used for heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription, the toxicity of cushion and strong.

Chinese medicine of the present invention has liver and kidney tonifying; benefiting qi and removing blood stasis; expelling wind and removing dampness; the effect of activating collaterals to relieve pain; be mainly used in the treatment of osteoarthritis; also can be used for merging application with the Western medicine of treatment osteoarthritis; and subchondral bone is holed or little fracture under cooperation intraarticular injection hyaluronic acid or the arthroscope; technical tie-ups such as organization engineered cartilage transplanting treatment osteoarthritis; to stop or to reverse the PD of osteoarthritis; performance is to the effect of osteoarthritis cartilage protection; improve the effect of osteoarthritis repair of cartilage; prevent the regression of regeneration of cartilage; reduce digestive tract; cardiovascular and renal complication incidence rate etc. have great clinical meaning.

Clinical observation:

(1) clinical data

The inventor carries out clinical observation treatment to 127 routine chronic nephritis patients in 2003 so far.Male's 46 examples wherein, women's 81 examples are between 43 to 69 years old age.

(2) Therapeutic Method

Oral, three times on the one, each 5～10g, one after each meal, 1 month is a course of treatment.

(3) curative effect judging standard

Cure: symptom all disappears; Main physics and chemistry detects index and is normally.

Produce effects: symptomatology is eliminated or cardinal symptom is eliminated; It is normal substantially that physics and chemistry detects index.

Effectively: cardinal symptom disappears substantially; Main physics and chemistry detects index and makes moderate progress.

Invalid: main physics and chemistry detects index and the preceding no change of treatment.

(4) therapeutic effect:

Clinical cure 106 examples, produce effects 13 examples, effective 4 examples, invalid 4 examples, all cases all have no adverse reaction.

(5) sum up:

Clinical time: 5～6 years, curative effect: 1 month effectively, and the course of treatment: general patient 2～3 months, symptom disappears substantially, the patient with severe symptoms: disease disappeared in 6 months, and symptom all disappeared in 8 months.Effective percentage 96.85%, cure rate 83.46%.

The present invention prepares simply, and good absorbing effect is evident in efficacy, has no side effect, and is safe, helps sufferer and in time alleviates condition of illness.

(4) specific embodiment

Embodiment 1:

Get Radix Dipsaci 6g, Radix Rehmanniae 9g, Fructus Corni 6g, Radix Achyranthis Bidentatae 6g, Radix Astragali 9g, Rhizoma Chuanxiong 3g, Radix Angelicae Sinensis 6g, Radix Alangii 1g, Cortex Acanthopancis 4g, Rhizoma Saururi (Herba Saururi) 9g, Spina Gleditsiae 3g, Ramulus Mori 12g, Flos Lonicerae 9g, Radix Scrophulariae 9g, Ramulus et Folium Actinidiae Polygamae 3g, pittosporm root 12g, Rhizoma Et Radix Notopterygii 3g, Radix Glycyrrhizae 6g, above-mentioned raw materials is cleaned up, place water to boil to paste, again that raw material is air-dry, pulverize is quantitatively taken behind the mix homogeneously.

Usage and dosage: oral, three times on the one, each 5～10g, one after each meal.

Embodiment 2:

Get Radix Dipsaci 12g, Radix Rehmanniae 15g, Fructus Corni 10g, Radix Achyranthis Bidentatae 12g, Radix Astragali 15g, Rhizoma Chuanxiong 9g, Radix Angelicae Sinensis 12g, Radix Alangii 3g, Cortex Acanthopancis 8g, Rhizoma Saururi (Herba Saururi) 15g, Spina Gleditsiae 9g, Ramulus Mori 18g, Flos Lonicerae 15g, Radix Scrophulariae 15g, Ramulus et Folium Actinidiae Polygamae 9g, pittosporm root 18g, Rhizoma Et Radix Notopterygii 9g, Radix Glycyrrhizae 10g, above-mentioned raw materials is cleaned up, place water to boil to paste, again that raw material is air-dry, pulverize is quantitatively taken behind the mix homogeneously.

Usage and dosage: oral, three times on the one, each 5～10g, one after each meal.

Embodiment 3:

Get Radix Dipsaci 9g, Radix Rehmanniae 12g, Fructus Corni 8g, Radix Achyranthis Bidentatae 9g, Radix Astragali 12g, Rhizoma Chuanxiong 6g, Radix Angelicae Sinensis 9g, Radix Alangii 2g, Cortex Acanthopancis 6g, Rhizoma Saururi (Herba Saururi) 12g, Spina Gleditsiae 6g, Ramulus Mori 15g, Flos Lonicerae 12g, Radix Scrophulariae 12g, Ramulus et Folium Actinidiae Polygamae 6g, pittosporm root 15g, Rhizoma Et Radix Notopterygii 6g, Radix Glycyrrhizae 8g, above-mentioned raw materials is cleaned up, place water to boil to paste, again that raw material is air-dry, pulverize is quantitatively taken behind the mix homogeneously.

Usage and dosage: oral, three times on the one, each 5～10g, one after each meal.

Claims (3)

1. Chinese medicine for the treatment of hyperosteogeny, osteoarthritis, it is characterized in that: the raw material by following parts by weight is formed:

6～12 parts of Radix Dipsacis, 9～15 parts of Radix Rehmanniaes, 6～10 parts of Fructus Corni, 6～12 parts of Radix Achyranthis Bidentataes, 9～15 parts of the Radixs Astragali, 3～9 parts of Rhizoma Chuanxiongs, 6～12 parts of Radix Angelicae Sinensis, 1～3 part of Radix Alangii, 4～8 parts of Cortex Acanthopanciss, 9～15 parts of Rhizoma Saururi (Herba Saururi)s, 3～9 parts of Spina Gleditsiaes, 12～18 parts of Ramulus Moris, 9～15 parts of Flos Loniceraes, 9～15 parts of Radix Scrophulariaes, 3～9 parts of Ramulus et Folium Actinidiae Polygamaes, 12～18 parts of pittosporm root, 3～9 parts of Rhizoma Et Radix Notopterygiis, 6～10 parts in Radix Glycyrrhizae.

2. treatment hyperosteogeny according to claim 1, the arthritic Chinese medicine of event, it is characterized in that: the raw material by following parts by weight is formed:

9 parts of Radix Dipsacis, 12 parts of Radix Rehmanniaes, 8 parts of Fructus Corni, 9 parts of Radix Achyranthis Bidentataes, 12 parts of the Radixs Astragali, 6 parts of Rhizoma Chuanxiongs, 9 parts of Radix Angelicae Sinensis, 2 parts of Radix Alangiis, 6 parts of Cortex Acanthopanciss, 12 parts of Rhizoma Saururi (Herba Saururi)s, 6 parts of Spina Gleditsiaes, 15 parts of Ramulus Moris, 12 parts of Flos Loniceraes, 12 parts of Radix Scrophulariaes, 6 parts of Ramulus et Folium Actinidiae Polygamaes, 15 parts of pittosporm root, 6 parts of Rhizoma Et Radix Notopterygiis, 8 parts in Radix Glycyrrhizae.

3. the Chinese medicine of treatment hyperosteogeny according to claim 1 and 2, osteoarthritis is characterized in that: described Chinese medicine is powder.