CN114787151B - 喹唑啉衍生物或其盐、或其药物组合物的用途 - Google Patents

喹唑啉衍生物或其盐、或其药物组合物的用途 Download PDF

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Publication number
CN114787151B
CN114787151B CN202080071551.0A CN202080071551A CN114787151B CN 114787151 B CN114787151 B CN 114787151B CN 202080071551 A CN202080071551 A CN 202080071551A CN 114787151 B CN114787151 B CN 114787151B
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China
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formula
compound
pharmaceutically acceptable
acceptable salt
pharmaceutical composition
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CN202080071551.0A
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English (en)
Chinese (zh)
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CN114787151A (zh
Inventor
杨朝强
封帆
葛琪
李琳
唐晓闻
王训强
尚磊
何佳丽
晏彩霞
董平
周杰
孙迎迎
许易
陈智林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Capital Pharmaceutical Holdings Beijing Co ltd
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Lianyungang Runzhong Pharmaceutical Co Ltd
Original Assignee
Capital Pharmaceutical Holdings Beijing Co ltd
Chia Tai Tianqing Pharmaceutical Group Co Ltd
Lianyungang Runzhong Pharmaceutical Co Ltd
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Publication of CN114787151A publication Critical patent/CN114787151A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN202080071551.0A 2019-11-01 2020-10-30 喹唑啉衍生物或其盐、或其药物组合物的用途 Active CN114787151B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019110594719 2019-11-01
CN201911059471 2019-11-01
PCT/CN2020/125384 WO2021083347A1 (fr) 2019-11-01 2020-10-30 Utilisation d'un dérivé de quinazoline ou d'un sel de celui-ci ou d'une composition pharmaceutique associée

Publications (2)

Publication Number Publication Date
CN114787151A CN114787151A (zh) 2022-07-22
CN114787151B true CN114787151B (zh) 2024-04-16

Family

ID=75714473

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CN202080071551.0A Active CN114787151B (zh) 2019-11-01 2020-10-30 喹唑啉衍生物或其盐、或其药物组合物的用途

Country Status (2)

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CN (1) CN114787151B (fr)
WO (1) WO2021083347A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015043515A1 (fr) * 2013-09-28 2015-04-02 正大天晴药业集团股份有限公司 Dérivé de quinazoline et son procédé de préparation
WO2016150340A1 (fr) * 2015-03-20 2016-09-29 正大天晴药业集团股份有限公司 Sels de dérivé de quinazoline et procédé de préparation associé
WO2018036539A1 (fr) * 2016-08-25 2018-03-01 正大天晴药业集团股份有限公司 Cristal de sel de dérivé de quinazoline

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA018716B1 (ru) * 2007-10-29 2013-10-30 Натко Фарма Лимитед Новые 4-(тетразол-5-ил) хиназолиновые производные в качестве противораковых средств

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015043515A1 (fr) * 2013-09-28 2015-04-02 正大天晴药业集团股份有限公司 Dérivé de quinazoline et son procédé de préparation
WO2016150340A1 (fr) * 2015-03-20 2016-09-29 正大天晴药业集团股份有限公司 Sels de dérivé de quinazoline et procédé de préparation associé
WO2018036539A1 (fr) * 2016-08-25 2018-03-01 正大天晴药业集团股份有限公司 Cristal de sel de dérivé de quinazoline

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Publication number Publication date
WO2021083347A1 (fr) 2021-05-06
CN114787151A (zh) 2022-07-22

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