CN114728933A - 5-ht2a受体抑制剂或反向激动剂及其制备方法和应用 - Google Patents

5-ht2a受体抑制剂或反向激动剂及其制备方法和应用 Download PDF

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CN114728933A
CN114728933A CN202180006171.3A CN202180006171A CN114728933A CN 114728933 A CN114728933 A CN 114728933A CN 202180006171 A CN202180006171 A CN 202180006171A CN 114728933 A CN114728933 A CN 114728933A
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CN114728933B (zh
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张睿
叶亮
马明旭
王文艳
代玉森
田京伟
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Shandong Luye Pharmaceutical Co Ltd
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Abstract

本发明涉及一种作为5‑HT2A受体抑制剂或反向激动剂的新化合物及其制备方法和药物组合物。还涉及含有所述化合物或药物组合物在制备治疗5‑HT2A受体相关疾病的药物中的应用，所述疾病包括帕金森病引起的非运动症状：妄想、幻觉、抑郁、焦虑、认知障碍、睡眠障碍；痴呆相关的精神疾病；重度抑郁症；或精神分裂的阴性症状等。

Description

PCT国内申请，说明书已公开。

Claims (10)

  1. PCT国内申请，权利要求书已公开。
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CN115850204A (zh) * 2022-11-26 2023-03-28 烟台大学 四氢苯并噻吩衍生物及其制备方法和应用

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WO2024027800A1 (zh) * 2022-08-03 2024-02-08 嘉奥制药（石家庄）有限公司 5-ht2a受体反向激动剂及其制备方法和应用

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WO2019040107A1 (en) * 2017-08-21 2019-02-28 Acadia Pharmaceuticals Inc. COMPOUNDS, CORRESPONDING SALTS AND METHODS FOR THE TREATMENT OF DISEASES
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