CN114712425A - Liver-protecting wine - Google Patents
Liver-protecting wine Download PDFInfo
- Publication number
- CN114712425A CN114712425A CN202210418791.4A CN202210418791A CN114712425A CN 114712425 A CN114712425 A CN 114712425A CN 202210418791 A CN202210418791 A CN 202210418791A CN 114712425 A CN114712425 A CN 114712425A
- Authority
- CN
- China
- Prior art keywords
- extract
- root
- liver
- white spirit
- content
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000016068 Berberis vulgaris Nutrition 0.000 claims abstract description 19
- 241000335053 Beta vulgaris Species 0.000 claims abstract description 19
- 210000004185 liver Anatomy 0.000 claims abstract description 19
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 16
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 16
- 241000219780 Pueraria Species 0.000 claims abstract description 14
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 claims abstract description 13
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 claims abstract description 13
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 claims abstract description 13
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 claims abstract description 13
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 claims abstract description 13
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 claims abstract description 13
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 claims abstract description 13
- 235000006545 Ziziphus mauritiana Nutrition 0.000 claims abstract description 13
- 244000126002 Ziziphus vulgaris Species 0.000 claims abstract description 13
- 235000008529 Ziziphus vulgaris Nutrition 0.000 claims abstract description 13
- 229960003237 betaine Drugs 0.000 claims abstract description 13
- 229930003944 flavone Natural products 0.000 claims abstract description 13
- 150000002212 flavone derivatives Chemical class 0.000 claims abstract description 13
- 235000011949 flavones Nutrition 0.000 claims abstract description 13
- 229940100243 oleanolic acid Drugs 0.000 claims abstract description 13
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 claims abstract description 13
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 12
- 241001247821 Ziziphus Species 0.000 claims abstract description 6
- 238000000034 method Methods 0.000 abstract description 2
- 230000003647 oxidation Effects 0.000 abstract description 2
- 238000007254 oxidation reaction Methods 0.000 abstract description 2
- 239000000126 substance Substances 0.000 abstract description 2
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 235000019441 ethanol Nutrition 0.000 description 11
- 238000002474 experimental method Methods 0.000 description 11
- 230000035622 drinking Effects 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 6
- 241001465754 Metazoa Species 0.000 description 5
- 208000022309 Alcoholic Liver disease Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 206010067125 Liver injury Diseases 0.000 description 3
- 238000001514 detection method Methods 0.000 description 3
- 210000003494 hepatocyte Anatomy 0.000 description 3
- 241000699666 Mus <mouse, genus> Species 0.000 description 2
- 238000010171 animal model Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 238000007490 hematoxylin and eosin (H&E) staining Methods 0.000 description 2
- 231100000753 hepatic injury Toxicity 0.000 description 2
- 208000019423 liver disease Diseases 0.000 description 2
- 230000017074 necrotic cell death Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 230000007863 steatosis Effects 0.000 description 2
- 231100000240 steatosis hepatitis Toxicity 0.000 description 2
- 230000008961 swelling Effects 0.000 description 2
- 206010012335 Dependence Diseases 0.000 description 1
- 206010016654 Fibrosis Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 206010019799 Hepatitis viral Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 231100000460 acute oral toxicity Toxicity 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 125000003158 alcohol group Chemical group 0.000 description 1
- 235000013334 alcoholic beverage Nutrition 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000000711 cancerogenic effect Effects 0.000 description 1
- 231100000357 carcinogen Toxicity 0.000 description 1
- 239000003183 carcinogenic agent Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 230000004761 fibrosis Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 238000003364 immunohistochemistry Methods 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 230000037356 lipid metabolism Effects 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 231100000682 maximum tolerated dose Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000003305 oral gavage Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 150000003254 radicals Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 201000001862 viral hepatitis Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
- C12G3/05—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides
- C12G3/055—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides extracted from plants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Abstract
The invention discloses a liver protection wine, which is prepared by mixing a kudzu root extract, a root beet extract, a Chinese date extract and white spirit according to a use ratio, wherein the use ratio of the kudzu root extract, the root beet extract, the Chinese date extract and the white spirit is 35-55 mg: 40-65 mg: 1-5 mg: 95-105ml, wherein the content of pueraria flavone in the pueraria extract is more than or equal to 60 percent; the content of betaine in the root beet extract is more than or equal to 90 percent; the oleanolic acid content in the jujube extract is more than or equal to 95 percent; the alcohol content of the white spirit is 35-55% (v/v), and the kudzu root extract, the root beet extract and the Chinese date extract which are prepared by the method respectively contain kudzu root flavone, betaine and oleanolic acid, are liver-protecting substances with the functions of resisting oxidation and inhibiting free radicals, and can effectively protect the liver in time.
Description
Technical Field
The invention relates to the technical field of compound wine, in particular to liver-protecting wine.
Background
In 2000, it was pointed out by 33 experts in liver disease, book of alcoholic liver disease: the alcoholic liver disease becomes the second largest liver disease cause only after viral hepatitis, the incidence rate is high, the consequence serious disease becomes the disease seriously harming the health of people, the prevention and the treatment of the alcoholic liver disease are highly regarded, and the alcoholic beverage is listed as a carcinogen by the world health organization in 2017.
However, the wine belongs to food, the invention has more than 7000 years history at present, and only China consumes 1300 million tons of white spirit every year. Drinking wine can injure the liver and is prohibited, so that the method is not feasible. In order to prevent alcohol damage to the liver, a healthy person can take liver protection medicines for prevention while drinking alcohol every time, and the possibility is low. The precondition for treating alcoholic liver disease is avoiding drinking, and because the drinking has the characteristic of causing people to be addicted, the drinking of a patient with drinking addiction has no feasibility like drinking. In addition to the social customs and folk customs, drinking with diseases is a common phenomenon. Today, in the field of human health and medical care, the food-borne diseases caused by drinking are still in an inelegant state;
the invention is characterized in that the invention comprises a liquor-making agent, a filter tip, a universal solvent and a drug-guiding agent, wherein the liquor-making agent comprises iodine, a mask, a safety belt and a filter tip, the invention also comprises a drug-making agent, a drug-making agent and a drug-making agent.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide liver-protecting wine.
In order to solve the technical problems, the technical scheme provided by the invention is a liver protection wine which is prepared by mixing a kudzu root extract, a root beet extract, a Chinese date extract and white spirit according to a use ratio, wherein the use ratio of the kudzu root extract, the root beet extract, the Chinese date extract and the white spirit is 35-55 mg: 40-65 mg: 1-5 mg: 95-105 ml.
Further, the liver protection wine is prepared by mixing a kudzu root extract, a root beet extract, a Chinese date extract and white spirit according to a proportion, wherein the use proportion of the kudzu root extract, the root beet extract, the Chinese date extract and the white spirit is 40 mg: 45 mg: 1.5 mg: 100 ml.
Furthermore, the content of pueraria flavone in the pueraria extract is more than or equal to 60 percent; the content of betaine in the root beet extract is more than or equal to 90 percent; the oleanolic acid content in the jujube extract is more than or equal to 95%, and the alcohol content of the white spirit is 35-55% (v/v).
Compared with the prior art, the invention has the advantages that: the prepared kudzu root extract, the root beet extract and the Chinese date extract respectively contain kudzu root flavone, betaine and oleanolic acid, are liver protection substances with oxidation resistance and free radical inhibition, can protect the liver timely and effectively, and are proved by scientific experiments of four months in one year by the Heilongjiang disease prevention and control center from 7 months in 2017 to 11 months in 2018, wherein each 100 milliliters of white spirit in the liver protection wine contains 40 milligrams of kudzu root flavone, 45 milligrams of betaine and 1.5 milligrams of oleanolic acid, so that the damage of alcohol to the liver can be effectively reduced.
Detailed Description
The liver-protecting wine of the present invention will be further described in detail with reference to the following examples.
Example 1
The liver protection wine is prepared by mixing a kudzu root extract, a root beet extract, a Chinese date extract and white spirit according to a proportion, wherein the use proportion of the kudzu root extract, the root beet extract, the Chinese date extract and the white spirit is 40 mg: 45 mg: 1.5 mg: 100ml, wherein the content of pueraria flavone in the pueraria extract is more than or equal to 60 percent; the content of betaine in the root beet extract is more than or equal to 90 percent; the oleanolic acid content in the jujube extract is more than or equal to 95%, and the alcohol content of the white spirit is 35-55% (v/v).
Example 2
During the period from 2017 to 2018, 11 months, the centers for preventing and controlling diseases in Heilongjiang province perform safety evaluation and animal experiments on the invention, and the specific contents are as follows:
1) safety evaluation test
The mouse is adopted to carry out an acute oral toxicity experiment and a feeding experiment for 30 days for comprehensive examination, and the result shows that the maximum tolerated dose MTD of the mouse acute toxicity experiment is more than 10.0g/kg BW, which is actually nontoxic; in addition, the weight increase condition of male and female mice in each dose group is good in a feeding experiment for 30 days, the conventional blood and biochemical indexes are not abnormal, and the main organs are not subjected to toxic pathological changes, so that the edible safety of pueraria flavone, betaine and oleanolic acid is proved.
2) Animal experiments
Dividing the experimental animals into 5 groups, including a blank control group (distilled water), a 45% (V/V) alcohol group, a 45% (V/V) alcohol 1-time group (added with pueraria flavone, betaine and oleanolic acid), a 45% (V/V) alcohol 5-time group (added with pueraria flavone, betaine and oleanolic acid) and a 45% (V/V) alcohol 10-time group (added with pueraria flavone, betaine and oleanolic acid), wherein each group comprises 8 experimental animals, and each dosage is set for two experimental periods of 4 weeks and 8 weeks;
the animals of each group are subjected to oral gavage, and are continuously gavage with 10ml/kg BW for 1 time per day;
the animals are sacrificed at 4 weeks and 8 weeks respectively, blood and liver of the animals are taken, and pathological histology examination (including HE staining and fat staining) and immunohistochemistry are carried out, and liver function detection, lipid metabolism detection and antioxidation detection are carried out at the same time;
the results of 4 weeks of experiments show that HE staining results of liver pathology show that: the results of the 4-week experiment show that alcohol can cause liver damage, which is manifested by hepatocyte swelling, steatosis and necrosis, interstitial edema and inflammatory thin chest infiltration. The white spirit added with pueraria flavone, betaine and oleanolic acid can improve liver injury caused by liquor drainage, wherein 5 times of 45% (V/V) alcohol has the best effect;
the 8-week experiment results show that the white spirit added with pueraria flavone, betaine and oleanolic acid can improve the fatty degeneration and fibrosis of the liver, and has no obvious effect of improving the swelling of liver cells and the lipofuscin deposition.
② from the aspects of reducing hepatic cell steatosis, fibroblast hyperplasia and hepatic cell necrosis, the 5 times group effect of 45% (V/V) alcohol is best;
the experiments prove that the liver protection wine provided by the invention has the effect of reducing alcoholic liver injury compared with the white spirit sold on the market on the premise of keeping the original taste of the wine due to the addition of the kudzu root extract, the root beet extract and the Chinese date extract in proportion.
The invention and its embodiments have been described above, without this being limitative. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (3)
1. The liver protection wine is characterized by being prepared by mixing a kudzu root extract, a root beet extract, a Chinese date extract and white spirit according to a use ratio, wherein the kudzu root extract, the root beet extract, the Chinese date extract and the white spirit are used in a ratio of 35-55 mg: 40-65 mg: 1-5 mg: 95-105 ml.
2. The liver protection wine as claimed in claim 1, wherein the liver protection wine is prepared by mixing radix puerariae extract, root beet extract, jujube extract and white spirit according to a proportion, and the use proportion of the radix puerariae extract, the root beet extract, the jujube extract and the white spirit is 40 mg: 45 mg: 1.5 mg: 100 ml.
3. The liver-protecting wine as claimed in any one of claims 1 to 2, wherein the content of pueraria flavone in the pueraria extract is not less than 60%; the content of betaine in the root beet extract is more than or equal to 90 percent; the oleanolic acid content in the jujube extract is more than or equal to 95%, and the alcohol content of the white spirit is 35-55% (v/v).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210418791.4A CN114712425A (en) | 2022-04-20 | 2022-04-20 | Liver-protecting wine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210418791.4A CN114712425A (en) | 2022-04-20 | 2022-04-20 | Liver-protecting wine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114712425A true CN114712425A (en) | 2022-07-08 |
Family
ID=82245893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210418791.4A Pending CN114712425A (en) | 2022-04-20 | 2022-04-20 | Liver-protecting wine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114712425A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101874857A (en) * | 2010-05-28 | 2010-11-03 | 劲牌有限公司 | Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof |
| CN111406856A (en) * | 2020-03-11 | 2020-07-14 | 天津科技大学 | Functional fermented beverage for dispelling effects of alcohol and protecting liver and preparation method thereof |
-
2022
- 2022-04-20 CN CN202210418791.4A patent/CN114712425A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101874857A (en) * | 2010-05-28 | 2010-11-03 | 劲牌有限公司 | Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof |
| CN111406856A (en) * | 2020-03-11 | 2020-07-14 | 天津科技大学 | Functional fermented beverage for dispelling effects of alcohol and protecting liver and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 耿贵等: "《食用甜菜栽培技术和加工利用》", 31 December 2007, 黑龙江科学技术出版社 * |
| 迟玉杰: "《保健食品学》", 31 May 2016, 中国轻工业出版社 * |
| 顾健: "《中国藏药：汉藏对照》", 31 October 2016, 民族出版社 * |
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Application publication date: 20220708 |