CN114621897B - 一株产琥珀酸的菌株及其生产琥珀酸的方法和应用 - Google Patents
一株产琥珀酸的菌株及其生产琥珀酸的方法和应用 Download PDFInfo
- Publication number
- CN114621897B CN114621897B CN202210320375.0A CN202210320375A CN114621897B CN 114621897 B CN114621897 B CN 114621897B CN 202210320375 A CN202210320375 A CN 202210320375A CN 114621897 B CN114621897 B CN 114621897B
- Authority
- CN
- China
- Prior art keywords
- succinic acid
- strain
- fermentation
- escherichia coli
- suc37
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 title claims abstract description 111
- 239000001384 succinic acid Substances 0.000 title claims abstract description 50
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 19
- 238000000855 fermentation Methods 0.000 claims abstract description 45
- 230000004151 fermentation Effects 0.000 claims abstract description 43
- 241000588724 Escherichia coli Species 0.000 claims abstract description 24
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 13
- 239000008103 glucose Substances 0.000 claims abstract description 13
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims abstract description 7
- 238000000034 method Methods 0.000 claims description 20
- 239000001963 growth medium Substances 0.000 claims description 13
- 239000001888 Peptone Substances 0.000 claims description 12
- 108010080698 Peptones Proteins 0.000 claims description 12
- 235000019319 peptone Nutrition 0.000 claims description 12
- 238000012258 culturing Methods 0.000 claims description 11
- 239000002609 medium Substances 0.000 claims description 11
- 239000007787 solid Substances 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 8
- 239000000047 product Substances 0.000 claims description 8
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims description 6
- 238000007670 refining Methods 0.000 claims description 6
- 238000001914 filtration Methods 0.000 claims description 5
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 claims description 5
- 239000001095 magnesium carbonate Substances 0.000 claims description 5
- 229910000021 magnesium carbonate Inorganic materials 0.000 claims description 5
- 238000011218 seed culture Methods 0.000 claims description 5
- OKUCEQDKBKYEJY-UHFFFAOYSA-N tert-butyl 3-(methylamino)pyrrolidine-1-carboxylate Chemical compound CNC1CCN(C(=O)OC(C)(C)C)C1 OKUCEQDKBKYEJY-UHFFFAOYSA-N 0.000 claims description 5
- 239000012065 filter cake Substances 0.000 claims description 4
- 150000007524 organic acids Chemical class 0.000 claims description 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 3
- 229920001817 Agar Polymers 0.000 claims description 3
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims description 3
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims description 3
- 238000005273 aeration Methods 0.000 claims description 3
- 239000008272 agar Substances 0.000 claims description 3
- 239000003729 cation exchange resin Substances 0.000 claims description 3
- 235000005822 corn Nutrition 0.000 claims description 3
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 3
- 235000018417 cysteine Nutrition 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 239000006228 supernatant Substances 0.000 claims description 3
- 239000002054 inoculum Substances 0.000 claims description 2
- 240000008042 Zea mays Species 0.000 claims 1
- 238000012262 fermentative production Methods 0.000 claims 1
- 235000005985 organic acids Nutrition 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 abstract description 12
- 239000002253 acid Substances 0.000 abstract description 5
- 238000005265 energy consumption Methods 0.000 abstract description 4
- 238000005516 engineering process Methods 0.000 abstract description 4
- 238000004321 preservation Methods 0.000 abstract description 4
- 238000004886 process control Methods 0.000 abstract description 3
- 230000000813 microbial effect Effects 0.000 abstract description 2
- 238000011020 pilot scale process Methods 0.000 abstract description 2
- 238000012360 testing method Methods 0.000 abstract description 2
- 238000012795 verification Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 9
- 239000013078 crystal Substances 0.000 description 7
- 230000008569 process Effects 0.000 description 7
- 238000002425 crystallisation Methods 0.000 description 5
- 230000008025 crystallization Effects 0.000 description 5
- 239000011347 resin Substances 0.000 description 5
- 229920005989 resin Polymers 0.000 description 5
- 239000002351 wastewater Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 150000003839 salts Chemical class 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- AIUDWMLXCFRVDR-UHFFFAOYSA-N dimethyl 2-(3-ethyl-3-methylpentyl)propanedioate Chemical class CCC(C)(CC)CCC(C(=O)OC)C(=O)OC AIUDWMLXCFRVDR-UHFFFAOYSA-N 0.000 description 3
- 238000005342 ion exchange Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 229940066779 peptones Drugs 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 241000209149 Zea Species 0.000 description 2
- 230000004075 alteration Effects 0.000 description 2
- OVYQSRKFHNKIBM-UHFFFAOYSA-N butanedioic acid Chemical compound OC(=O)CCC(O)=O.OC(=O)CCC(O)=O OVYQSRKFHNKIBM-UHFFFAOYSA-N 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000008929 regeneration Effects 0.000 description 2
- 238000011069 regeneration method Methods 0.000 description 2
- 239000011734 sodium Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 description 1
- 239000002028 Biomass Substances 0.000 description 1
- 241000588722 Escherichia Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 235000011054 acetic acid Nutrition 0.000 description 1
- 150000001447 alkali salts Chemical class 0.000 description 1
- 150000008064 anhydrides Chemical class 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010170 biological method Methods 0.000 description 1
- 239000012267 brine Substances 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 238000009903 catalytic hydrogenation reaction Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000010981 drying operation Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000019253 formic acid Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 229910001629 magnesium chloride Inorganic materials 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- GFKXPVFCUXHGEB-UHFFFAOYSA-L magnesium;butanedioate Chemical compound [Mg+2].[O-]C(=O)CCC([O-])=O GFKXPVFCUXHGEB-UHFFFAOYSA-L 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 description 1
- 238000009629 microbiological culture Methods 0.000 description 1
- 239000012452 mother liquor Substances 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 239000003345 natural gas Substances 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000012492 regenerant Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 210000004767 rumen Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000010865 sewage Substances 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- HPALAKNZSZLMCH-UHFFFAOYSA-M sodium;chloride;hydrate Chemical compound O.[Na+].[Cl-] HPALAKNZSZLMCH-UHFFFAOYSA-M 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/54—Acetic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210320375.0A CN114621897B (zh) | 2022-03-29 | 2022-03-29 | 一株产琥珀酸的菌株及其生产琥珀酸的方法和应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210320375.0A CN114621897B (zh) | 2022-03-29 | 2022-03-29 | 一株产琥珀酸的菌株及其生产琥珀酸的方法和应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN114621897A CN114621897A (zh) | 2022-06-14 |
CN114621897B true CN114621897B (zh) | 2024-02-27 |
Family
ID=81904525
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202210320375.0A Active CN114621897B (zh) | 2022-03-29 | 2022-03-29 | 一株产琥珀酸的菌株及其生产琥珀酸的方法和应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114621897B (zh) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2925068A1 (fr) * | 2007-12-13 | 2009-06-19 | Roquette Freres | Procedes de production d'acide succinique |
CN102286415A (zh) * | 2011-09-07 | 2011-12-21 | 天津工业生物技术研究所 | 琥珀酸高产菌株及其应用 |
CN102533622A (zh) * | 2012-03-06 | 2012-07-04 | 江南大学 | 一株产琥珀酸的琥珀酸放线杆菌 |
CN102864113A (zh) * | 2012-10-16 | 2013-01-09 | 南京工业大学 | 产丁二酸的菌株及其生产丁二酸的方法和应用 |
CN112239738A (zh) * | 2020-10-29 | 2021-01-19 | 江南大学 | 一株产琥珀酸的大肠杆菌及其应用 |
-
2022
- 2022-03-29 CN CN202210320375.0A patent/CN114621897B/zh active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2925068A1 (fr) * | 2007-12-13 | 2009-06-19 | Roquette Freres | Procedes de production d'acide succinique |
CN102286415A (zh) * | 2011-09-07 | 2011-12-21 | 天津工业生物技术研究所 | 琥珀酸高产菌株及其应用 |
CN102533622A (zh) * | 2012-03-06 | 2012-07-04 | 江南大学 | 一株产琥珀酸的琥珀酸放线杆菌 |
CN102864113A (zh) * | 2012-10-16 | 2013-01-09 | 南京工业大学 | 产丁二酸的菌株及其生产丁二酸的方法和应用 |
CN112239738A (zh) * | 2020-10-29 | 2021-01-19 | 江南大学 | 一株产琥珀酸的大肠杆菌及其应用 |
Also Published As
Publication number | Publication date |
---|---|
CN114621897A (zh) | 2022-06-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN109504719B (zh) | 一种提高谷氨酸产酸率及提取率的方法 | |
CN109504720B (zh) | 谷氨酸的绿色生产工艺 | |
CN110272341A (zh) | 一种长链二元酸的提纯方法 | |
CN110616158B (zh) | 一种维斯假丝酵母发酵生产十二碳二元酸的方法 | |
CN111662848B (zh) | 耐盐地衣芽孢杆菌a-a2-10的培养方法及应用 | |
CN1246156A (zh) | 新型细菌菌株和其在2-酮-l-古洛糖酸发酵生产工艺中的应用 | |
CN112322556B (zh) | 耐受高盐环境的尼泊尔葡萄球菌及培养方法 | |
CN109628513B (zh) | 一种氨基酸发酵培养基及其制备方法 | |
CN100338221C (zh) | 从含有戊糖的底物制备乳酸 | |
CN110627213A (zh) | 一种微藻光发酵法高效处理高氨氮废水的方法 | |
CN110205268B (zh) | 一株微杆菌及其在转化芦苇秸秆水解物制备微生物絮凝剂中的应用 | |
CN110791462A (zh) | 一株枯草芽孢杆菌及其在发酵生产腺苷中的应用 | |
CN116716231B (zh) | 一株大肠埃希氏菌及其在发酵生产色氨酸中的应用 | |
CN117126898B (zh) | 一种通过生物技术制备缬氨酸的工艺 | |
CN110759754B (zh) | 一种氨基葡萄糖发酵菌渣无害化处理及资源化利用方法 | |
CN114621897B (zh) | 一株产琥珀酸的菌株及其生产琥珀酸的方法和应用 | |
CN106244638B (zh) | 一种生物质循环发酵生产乳酸的综合利用工艺 | |
CN110029134B (zh) | 一种生产和提取谷氨酸的工艺 | |
CN109266578B (zh) | 大肠埃希氏菌ACThr1032及其在发酵生产L-苏氨酸中的应用 | |
CN114958631B (zh) | 一种利用重相乳酸生产单细胞蛋白的方法 | |
CN110408672B (zh) | 一种从d-乳酸废液中提取d-乳酸的方法 | |
CN110564785B (zh) | 一种维斯假丝酵母发酵生产十一碳二元酸的方法 | |
CN87100655A (zh) | 生产l-山梨糖的方法 | |
CN110564784A (zh) | 一种维斯假丝酵母发酵生产十四碳二元酸的方法 | |
CN109628507A (zh) | 一种造纸废液制备乳酸的方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20240130 Address after: 255000 No. 266, New Village West Road, Zhangdian District, Zibo, Shandong Applicant after: Shandong University of Technology Country or region after: China Applicant after: Shanli Dakang Food Technology (Zibo) Co.,Ltd. Address before: 255000 No. 266, New Village West Road, Zhangdian District, Zibo, Shandong Applicant before: Shandong University of Technology Country or region before: China |
|
GR01 | Patent grant | ||
GR01 | Patent grant |