CN114601909A - Traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain as well as preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain as well as preparation method and application thereof Download PDFInfo
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- CN114601909A CN114601909A CN202210243613.2A CN202210243613A CN114601909A CN 114601909 A CN114601909 A CN 114601909A CN 202210243613 A CN202210243613 A CN 202210243613A CN 114601909 A CN114601909 A CN 114601909A
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The raw materials comprise the following raw materials in parts by weight: 40-50 parts of folium artemisiae argyi, 20-30 parts of rhizoma zingiberis, 15-20 parts of rhizoma gastrodiae, 8-15 parts of pseudo-ginseng, 10-20 parts of polygonum multiflorum, 10-15 parts of musk, 5-10 parts of realgar, 5-10 parts of borneol and 5-10 parts of saffron. The preparation method comprises the following steps: weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with ethanol solution, soaking for 10min-30min, adding edible vinegar solution, decocting for three times, performing solid-liquid separation, and mixing the medicinal liquids to obtain the Chinese medicinal composition. Therefore, the traditional Chinese medicine composition has good treatment effect on symptoms caused by lumbar disc herniation and cervical hyperplasia. Meanwhile, vinegar is used for promoting the percutaneous absorption capability of the composition, so that scars on the surface of the skin can be avoided while the drug effect is improved.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, a preparation method and application thereof.
Background
Lumbar muscle strain, also known as functional lumbago, chronic lower lumbar injury, lumbar gluteal myofascitis and the like, is chronic injury inflammation of lumbar muscles and fascia at attachment points or periosteum of the lumbar muscles, is one of common causes of lumbago, has main symptoms of distending pain, soreness and repeated attack of the lumbar or lumbosacral parts, can change along with climate change or fatigue degree, is a common clinical disease, and is mainly characterized in that degenerated lumbar intervertebral discs on lumbar vertebrae gradually lose water, intervertebral spaces become narrow, fibrous rings relax and bulge to the periphery, vertebral body instability occurs, the fibrous rings tear outside the edges of the vertebral bodies to cause outward protrusion of nucleus pulposus in the fibrous rings, the periosteum of posterior longitudinal ligaments is jacked up to stimulate generation of new bone below the periosteum, and accordingly, bony spur or osteophyte is formed, which is called as lumbar hyperosteogeny or lumbar hyperosteogeny for short.
At present, no method for radically treating lumbar muscle strain and lumbar hyperplasia exists, and the disease can be relieved only through proper functional exercise and drug treatment. While the western medicine treatment mainly comprises oral anti-inflammatory analgesic, non-steroidal anti-inflammatory drug, injection corticosteroid, local external muscle relaxing drug and analgesic, and the drugs only can achieve the purpose of temporarily relieving pain, and once the drugs are stopped, the phenomenon of repeated diseases can occur, so that the physical and mental afflictions of patients are increased.
Moxibustion with Chinese herbs is one of the methods for treating the above diseases, but after moxibustion, the affected part has scars, which not only can injure the skin of a patient, but also can leave scars, and the scars are not easy to remove.
Therefore, in order to overcome the above disadvantages, it is important to develop a composition with good therapeutic effect and no scar left.
Disclosure of Invention
The invention aims to provide a preparation method of a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain.
The invention also aims to provide the traditional Chinese medicine composition for treating the hyperosteogeny and the lumbar muscle strain, which can quickly treat the hyperosteogeny, the lumbar muscle strain and the like and has good treatment effect.
The invention also aims to provide the application of the traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, which can improve the application capability of the traditional Chinese medicine composition, can avoid scars left at the using position of a patient and has higher practical value.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
In a first aspect, the present application provides a method for preparing a Chinese medicinal composition for treating hyperosteogeny and lumbar muscle strain, comprising the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with ethanol solution, soaking for 30min, adding edible vinegar solution, decocting for three times, performing solid-liquid separation, and mixing medicinal liquids to obtain the Chinese medicinal composition; the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 40-50 parts of folium artemisiae argyi, 20-30 parts of rhizoma zingiberis, 15-20 parts of rhizoma gastrodiae, 8-15 parts of pseudo-ginseng, 10-20 parts of polygonum multiflorum, 10-15 parts of musk, 5-10 parts of realgar, 5-10 parts of borneol and 5-10 parts of saffron.
In a second aspect, the present application provides a Chinese medicinal composition prepared by the above preparation method for treating hyperosteogeny and lumbar muscle strain.
In a third aspect, the application provides an application of a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, namely, the traditional Chinese medicine composition is used as an external liniment.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
firstly, the invention adopts wild mugwort leaf, ginger, gastrodia elata, pseudo-ginseng, fleece-flower root and safflower as main synthetic liquid to relieve pain, activate collaterals, induce resuscitation, relax tendons and relieve pain, musk is used for penetrating bones, dissipating blood stasis and relieving pain, realgar is used for detoxifying and sterilizing to jointly play the effects of activating blood, dredging channels, relieving swelling and relieving pain, vinegar is used for decocting and eliminating self toxin of the used medicines, and the using effect is improved. Has good treatment effect on cerebral ischemia, headache, dizziness, numbness of limbs, severe pain of lumbar vertebra and shoulder joints, arthritis and rheumatism pain caused by lumbar disc herniation and cervical hyperplasia.
Secondly, the vinegar is used as a solvent to decoct the traditional Chinese medicine raw materials, so that the active ingredients of the raw materials are dissolved out, the percutaneous absorption of the traditional Chinese medicine composition is promoted, and the use value is high.
Thirdly, when the traditional Chinese medicine composition is used as an external liniment, on one hand, the external liniment can not leave scars on the skin surface of a patient when in use, and on the other hand, the external liniment is convenient for the patient to use in various environments and is better in use.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
In a first aspect, the present application provides a method for preparing a Chinese medicinal composition for treating hyperosteogeny and lumbar muscle strain, comprising the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with ethanol solution, soaking for 30min, adding edible vinegar solution, decocting for three times, performing solid-liquid separation, and mixing medicinal liquids to obtain the Chinese medicinal composition; the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 40-50 parts of folium artemisiae argyi, 20-30 parts of rhizoma zingiberis, 15-20 parts of rhizoma gastrodiae, 8-15 parts of pseudo-ginseng, 10-20 parts of polygonum multiflorum, 10-15 parts of musk, 5-10 parts of realgar, 5-10 parts of borneol and 5-10 parts of saffron.
Folium artemisiae argyi: pungent and bitter taste, warm nature; has little toxicity. It enters liver, spleen and kidney meridians. Dispel cold to alleviate pain, warm meridians to stop bleeding. Can be used for treating lower abdomen psychroalgia, irregular menstruation, infertility due to cold womb, hematemesis, epistaxis, metrorrhagia, metrostaxis, and pregnancy bleeding; externally treating skin pruritus; vinegar moxa charcoal is used for warming meridians and stopping bleeding; can be used for treating hemorrhage due to deficiency cold.
It should be noted that in the present application, the folium artemisiae argyi is selected from wild folium artemisiae argyi.
Dried ginger: pungent and warm in flavor, enter spleen, stomach, kidney, heart and lung meridians, warm middle energizer to dispel cold, return yang to activate pulse, warm lung to resolve fluid retention, and can be used for treating abdominal psychroalgia, emesis, diarrhea, cold limbs, slight pulse, cough and asthma due to cold fluid retention.
Gastrodia elata: sweet taste, neutral nature, entering liver meridian, extinguishing wind and relieving convulsion, suppressing liver yang, dispelling pathogenic wind and dredging collaterals, and can be used for treating giddiness, headache, limbs anesthesia, hand and foot paralysis, rheumatalgia, etc.
Pseudo-ginseng: sweet, slightly bitter and warm in nature. It enters liver and stomach meridians. Disperse blood stasis, stop bleeding, resolve swelling and alleviate pain. Can be used for treating hemoptysis, hematemesis, epistaxis, hematochezia, metrorrhagia, traumatic hemorrhage, thoracico-abdominal pain, and traumatic swelling and pain.
Polygonum multiflorum: bitter, sweet, astringent and warm in nature. It enters liver, heart and kidney meridians. Remove toxicity, cure abscess, moisten intestines and relax bowels. Can be used for treating scrofula, sore, carbuncle, rubella, pruritus, constipation due to intestinal dryness, and hyperlipidemia.
Musk: pungent flavor and warm nature. It enters heart and spleen meridians. Inducing resuscitation and refreshing mind, promoting blood circulation and dredging channels, and relieving swelling and pain. Can be used for treating fever unconsciousness, apoplexy with phlegm syncope, qi stagnation with sudden syncope, central nausea and coma, amenorrhea, abdominal mass, dystocia, stillbirth, heart and abdomen pain, carbuncle, lymphoid tuberculosis, sore throat, traumatic injury, and numbness pain.
Realgar: pungent taste and warm nature; is toxic. It enters liver and large intestine meridians. Detoxify and kill parasites, dry dampness and dispel phlegm, check malaria. Can be used for treating carbuncle, furuncle, snake and insect bite, abdominal pain due to parasitic infestation, epilepsy, and malaria.
Borneol: pungent and bitter in flavor, slightly cold in nature, entering heart, spleen and lung meridians. Induce resuscitation and refresh mind, clear heat and alleviate pain. Can be used for treating fever unconsciousness, convulsion syncope, apoplexy, phlegm syncope, qi stagnation, sudden syncope, coma, conjunctival congestion, aphtha, sore throat, and purulence in ear canal.
Safflower carthamus: can effectively expand peripheral blood vessels, effectively inhibit platelet aggregation, reduce blood pressure, properly improve anoxia resistance and have certain protection effect on ischemic encephalopathy. Tranquilizing and analgesic effects.
In conclusion, the invention adopts wild mugwort leaf, ginger, gastrodia elata, pseudo-ginseng, fleece-flower root and safflower as main liquid for relieving pain, activating collaterals, inducing resuscitation, relaxing tendons and relieving pain, musk for penetrating bones, dissipating blood stasis and relieving pain, realgar for detoxifying and sterilizing to jointly play the effects of activating blood, dredging channels, relieving swelling and relieving pain, vinegar is used for decocting and eliminating the self toxin of the used medicine, and the good effect of the medicine is fully dissolved in the liquid. Has good treatment effect on cerebral ischemia, headache, dizziness, numbness of limbs, severe pain of lumbar vertebra and shoulder joints, arthritis and rheumatism pain caused by lumbar disc herniation and cervical hyperplasia.
The traditional Chinese medicine raw materials are selected, subjected to impurity removal and cleaned before being mixed. And the cleaning mode adopts ultrasonic equipment for cleaning.
After cleaning, slicing can be carried out, and then the raw materials are mixed to prepare a mixture.
And soaking the mixture in ethanol solution to make the ethanol solution penetrate the cell wall of the material and reduce the surface activity of the material. After the immersion is finished, the vinegar solution is added into the vinegar for decoction for three times, so that the vinegar can quickly exert the action of a solvent, active ingredients in the vinegar are dissolved out, the raw materials are softened, the dissolution amount of the active ingredients is further improved, and the efficacy value of the traditional Chinese medicine composition is enhanced.
In the application, after the vinegar solution is added for the first time, the mixture is decocted for 6 to 8 hours at the temperature of between 100 and 120 ℃. That is, the raw material added with the vinegar solution is decocted with slow fire, so that the effective components in the raw material are fully dissolved.
In the application, the mass ratio of the dosage of the first vinegar solution, the dosage of the second vinegar solution and the dosage of the third vinegar solution is (3-5):2:1, the decocting time after the vinegar is added for the second time is 2-3 h, and the decocting time after the vinegar is added for the third time is 30-40 min. The dosage of the vinegar solution is gradually reduced, the decoction time is shortened, and at the moment, the residual effective components in the dregs of a decoction can be further extracted, so that the dissolution rate of the effective components is improved, and the effect is better.
In the application, the volume ratio of vinegar to water in the vinegar solution is (4-5): 1. Under the conditions, the damage to the skin caused by high content of vinegar can be avoided.
In addition, in the present application, the acidity of vinegar is 5% to 8%.
In the present application, the volume ratio of the vinegar solution to the 55 voL-65 vol% ethanol solution is (3-5): 2. The ethanol solution is used for reducing the surface activity of the traditional Chinese medicine raw materials, and then the vinegar is used for softening the traditional Chinese medicine raw materials, so that the dissolution speed and the dissolution amount of the effective components are improved.
In the application, in order to avoid the loss of volatile components of the traditional Chinese medicine materials along with the volatilization of ethanol in the decocting process, distillate can be collected in the decocting process and mixed with liquid medicine.
In the application, the traditional Chinese medicine composition also comprises the following raw materials in parts by weight: 4-6 parts of ligusticum wallichii, 6-8 parts of eucommia ulmoides, 1-3 parts of root of kadsura heteroclita and 2-4 parts of mistletoe.
The rhizoma ligustici wallichii is pungent in taste and warm in nature, has the effects of promoting qi circulation and relieving depression, dispelling wind-dryness and dampness, and activating blood and relieving pain, and is mainly used for treating diseases such as wind-cold headache and dizziness, hypochondriac pain and abdominal pain, cold arthralgia, spasm of muscles, amenorrhea, dystocia, postpartum stasis and pain, carbuncle, ulcer and the like. The eucommia bark is pungent in taste and neutral in nature, has the effects of tonifying liver and kidney, strengthening bones and muscles and preventing miscarriage, and is mainly used for treating diseases such as soreness and pain of waist and back, flaccidity of feet and knees, dribbling urination, pruritus vulvae due to dampness, vaginal leakage, abortion, threatened abortion, hypertension and the like. The root of Camphora acuminate enters liver and lung meridians, has the efficacy of dispelling wind and eliminating dampness, and is mainly used for treating wind-damp spasm and pain, skin wind swelling and other diseases. Herba Visci has effects of relieving rigidity of muscles and activating collaterals, promoting blood circulation and removing blood stasis, and can be used for treating bone and muscle pain, limb spasm, waist and back pain and traumatic injury etc. Therefore, the medicine can further treat hyperosteogeny and lumbar muscle strain and can achieve the effect of quickly relieving pain.
In the application, the traditional Chinese medicine composition also comprises the following raw materials in parts by weight: 5-8 parts of pyrola, 12-20 parts of radish seed, 8-15 parts of cynomorium songaricum and 3-4 parts of radix angelicae pubescentis.
Wherein, the herba Pyrolae is warm in nature, sweet and bitter in taste. It enters lung, stomach, liver and kidney meridians. Has effects in tonifying deficiency, invigorating kidney, expelling pathogenic wind, removing dampness, promoting blood circulation, regulating menstruation, relieving cough, and stopping bleeding. Can be used for treating lumbago due to kidney deficiency, rheumatalgia, flaccidity of tendons and bones, hematemesis, epistaxis, metrorrhagia, and traumatic hemorrhage. Radish seed is pungent and sweet in flavor, has mild nature, enters lung, spleen and stomach channels, has the effects of promoting digestion, relieving flatulence, descending qi, reducing phlegm and the like, and is used for treating diseases such as diet stagnation, abdominal distension and pain, constipation, stagnation and diarrhea, phlegm stagnation and cough with dyspnea and cough and the like. The cynomorium songaricum is sweet in taste and warm in nature, has the effects of tonifying kidney yang, benefiting essence and blood and relaxing bowel, and is used for treating symptoms such as kidney yang deficiency, essence and blood deficiency, waist and knee atrophy and weakness, impotence and spermatorrhea, constipation due to intestinal dryness and the like. Radix Angelicae Pubescentis is pungent and bitter in flavor and slightly warm in nature, enters kidney and bladder channels, has effects of dispelling pathogenic wind, removing dampness, dredging arthralgia and relieving pain, and can be used for treating anemofrigid-damp arthralgia, pain of waist and knee, shaoyin wind-syndrome headache, and anemofrigid-damp headache. Therefore, the raw materials can further improve the action effect of the traditional Chinese medicine composition.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment aims to provide a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, which comprises the following raw materials: 45g of wild mugwort leaf, 25g of dried ginger, 18g of gastrodia elata, 12g of pseudo-ginseng, 15g of polygonum multiflorum, 13g of musk, 8g of realgar, 7g of borneol and 8g of saffron.
The preparation method comprises the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with 60 vol% ethanol solution, soaking for 20min, adding edible vinegar solution for the first time, decocting at 110 deg.C, and filtering after 8 hr to obtain residue I and medicinal liquid I; adding edible vinegar solution into the first residue for the second time, decocting for 2 hr, and filtering to obtain second residue and second medicinal liquid; adding edible vinegar solution into the residue II, decocting for 35min, and filtering to obtain medicinal liquid III; mixing the first liquid medicine, the second liquid medicine and the third liquid medicine to obtain the traditional Chinese medicine composition. Wherein the mass ratio of the first edible vinegar solution dosage, the second edible vinegar solution dosage and the third edible vinegar solution dosage is 4:2:1, and the volume ratio of edible vinegar (acidity 5%) to water in the edible vinegar solution is 4: 1.
Example 2
The embodiment aims to provide a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, which comprises the following raw materials: 45g of wild mugwort leaf, 25g of dried ginger, 18g of gastrodia elata, 12g of pseudo-ginseng, 15g of polygonum multiflorum, 13g of musk, 8g of realgar, 7g of borneol, 8g of saffron, 5g of ligusticum wallichii, 7g of eucommia ulmoides, 2g of shanbu ginger root and 3g of mistletoe.
The preparation method comprises the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with 60 vol% ethanol solution, soaking for 20min, adding edible vinegar solution for the first time, decocting at 110 deg.C, and filtering after 8 hr to obtain residue I and medicinal liquid I; adding edible vinegar solution into the first residue for the second time, decocting for 2 hr, and filtering to obtain second residue and second medicinal liquid; adding edible vinegar solution into the residue II for the third time, decocting for 35min, and filtering to obtain medicinal liquid III; mixing the first liquid medicine, the second liquid medicine and the third liquid medicine to obtain the traditional Chinese medicine composition. Wherein the mass ratio of the first edible vinegar solution dosage, the second edible vinegar solution dosage and the third edible vinegar solution dosage is 4:2:1, and the volume ratio of edible vinegar (acidity 5%) to water in the edible vinegar solution is 4: 1.
Example 3
The embodiment aims to provide a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, which comprises the following raw materials: 45g of wild mugwort leaf, 25g of dried ginger, 18g of gastrodia elata, 12g of pseudo-ginseng, 15g of polygonum multiflorum, 13g of musk, 8g of realgar, 7g of borneol, 8g of saffron, 5g of ligusticum wallichii, 7g of eucommia ulmoides, 2g of shanzhu ginger root, 3g of mistletoe, 6g of pyrola, 18g of radish seed, 10g of cynomorium songaricum and 3g of radix angelicae pubescentis.
The preparation method comprises the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with 60 vol% ethanol solution, soaking for 20min, adding edible vinegar solution for the first time, decocting at 110 deg.C, and filtering after 8 hr to obtain residue I and medicinal liquid I; adding edible vinegar solution into the first residue for the second time, decocting for 2 hr, and filtering to obtain second residue and second medicinal liquid; adding edible vinegar solution into the residue II for the third time, decocting for 35min, and filtering to obtain medicinal liquid III; mixing the first liquid medicine, the second liquid medicine and the third liquid medicine to obtain the traditional Chinese medicine composition. Wherein the mass ratio of the first edible vinegar solution dosage, the second edible vinegar solution dosage and the third edible vinegar solution dosage is 4:2:1, and the volume ratio of edible vinegar (acidity 5%) to water in the edible vinegar solution is 4: 1.
Example 4
The embodiment aims to provide a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, which comprises the following raw materials: 40g of wild mugwort leaf, 20g of dried ginger, 15g of gastrodia elata, 8g of pseudo-ginseng, 10g of polygonum multiflorum, 10g of musk, 5g of realgar, 5g of borneol, 5g of saffron, 4g of ligusticum wallichii, 6g of eucommia ulmoides, 1g of shanzhu ginger root, 2g of mistletoe, 5g of pyrola, 12g of radish seed, 8g of cynomorium songaricum and 3g of radix angelicae pubescentis.
The preparation method comprises the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with 55 vol% ethanol solution, soaking for 10min, adding edible vinegar solution for the first time, decocting at 100 deg.C, and filtering after 6 hr to obtain residue I and medicinal liquid I; adding edible vinegar solution into the first residue for the second time, decocting for 2 hr, and filtering to obtain second residue and second medicinal liquid; adding edible vinegar solution into the residue II for the third time, decocting for 30min, and filtering to obtain medicinal liquid III; collecting distillate during decocting process; mixing the first liquid medicine, the second liquid medicine, the third liquid medicine and the distillate to obtain the traditional Chinese medicine composition. Wherein the mass ratio of the first edible vinegar solution dosage, the second edible vinegar solution dosage and the third edible vinegar solution dosage is 3:2:1, and the volume ratio of edible vinegar (acidity 7%) to water in the edible vinegar solution is 4.5: 1.
Example 5
The embodiment aims to provide a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain, which comprises the following raw materials: 50g of wild mugwort leaf, 30g of dried ginger, 20g of gastrodia elata, 15g of pseudo-ginseng, 20g of polygonum multiflorum, 15g of musk, 10g of realgar, 10g of borneol, 10g of saffron, 6g of ligusticum wallichii, 8g of eucommia ulmoides, 3g of shanzhu ginger root, 4g of mistletoe, 8g of pyrola, 20g of radish seed, 15g of cynomorium songaricum and 4g of radix angelicae pubescentis.
The preparation method comprises the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with 65 vol% ethanol solution, soaking for 30min, adding edible vinegar solution for the first time, decocting at 120 deg.C, and filtering after 7 hr to obtain residue I and medicinal liquid I; adding edible vinegar solution into the first residue for the second time, decocting for 3 hr, and filtering to obtain second residue and second medicinal liquid; adding edible vinegar solution into the residue II for the third time, decocting for 40min, and filtering to obtain medicinal liquid III; collecting distillate during decocting process; mixing the first liquid medicine, the second liquid medicine, the third liquid medicine and the distillate to obtain the traditional Chinese medicine composition. Wherein the mass ratio of the first edible vinegar solution dosage, the second edible vinegar solution dosage and the third edible vinegar solution dosage is 5:2:1, and the volume ratio of edible vinegar (acidity 8%) to water in the edible vinegar solution is 5: 1.
Comparative example 1
This comparative example differs from example 1 in that the feedstock in this comparative example was not subjected to ethanol impregnation.
Comparative example 2
The comparative example is different from example 1 in that, in the comparative example, after the first addition of the vinegar solution, the decoction is carried out under the condition of middle fire (180 ℃ -220 ℃).
Effect example 1
282 patients with lumbar muscle strain and hyperosteogeny were collected, the age range was 34-67 years, the average age was (57.12 + -5.341) years, the treatment effect was observed by using the Chinese medicinal compositions prepared in examples 1-5, comparative example 1 and comparative example 2, respectively, and the treatment effect was divided into 7 groups according to the symptoms. In addition, the statistical analysis shows that p is more than 0.05 and is comparable.
The using method comprises the following steps: the prepared traditional Chinese medicine composition is externally applied to the affected part by 30mL each time, and is kneaded in the external application process, the treatment is carried out for 2 times per week, and the treatment effect is counted after 2 months of continuous treatment. The results are shown in Table 1.
The standard of therapeutic effect refers to the standard of therapeutic effect of Chinese medicine diagnosis issued by the State administration of traditional Chinese medicine. And (3) curing: the pain and the tenderness disappear, the function is recovered, and the patient can participate in work and labor; the effect is shown: the pain and the tenderness are obviously relieved, the symptoms are improved earlier, the function is basically recovered, and the traditional Chinese medicine preparation can participate in work and labor; and (4) invalidation: no change in symptoms and signs. Effective rate (cure number + significant number)/total number of people.
TABLE 1 therapeutic Effect
As can be seen from Table 1, after two months of treatment, the traditional Chinese medicine composition prepared by the embodiment of the invention has very good curative effect on lumbar muscle strain, hyperosteogeny, joint hyperplasia, arthritis, rheumatalgia and other diseases by moxibustion. In addition, in the treatment process, no scar is left on the skin of the patient, and the using effect of the patient is better.
Effect example 2
The particulars of a typical case during the course of treatment are as follows:
the first patient: zhuxx, female, 55 years old, attending physician in cardiology department at people hospital xx for more than thirty years. The occupational diseases cause blood supply insufficiency of carotid artery, and cause dizziness, chest distress, emesis and insomnia. After the external liniment (the traditional Chinese medicine composition prepared in example 1) is used, the cervical vertebra pain is obviously relieved after one week of treatment, and the cervical spondylosis is improved after one month of treatment by using the external liniment, and the relapse situation is not caused.
The second patient: zhao xx, male, 46 years old, ren xxx company office assistant main and ren, now engaged in catering shop. The waist pain is often absent and can not work adequately, so the pain is very painful. By using the external liniment (the traditional Chinese medicine composition prepared in example 1), the lumbar pain is obviously relieved after one week of treatment. After the external liniment is used for one month, the lumbar vertebra diseases never recur.
The third patient: wang xx, male, 50 years old, now the xxx mining limited ore dressing plant is engaged in the machine repair work. The lumbago caused by incapability of working is often absent and misworked, which is very painful. By using the external liniment (the traditional Chinese medicine composition prepared in example 1), the lumbar pain is obviously relieved after one week of treatment. After the external liniment is used for one month, the lumbar vertebra disease never recurs.
The fourth patient: wanx, female, age 41, worked in xxx mining, inc office, now owned by beauty shop. The waist often pain affects life and work, and is very painful. By using the external liniment (the traditional Chinese medicine composition prepared in example 1), the lumbar pain is obviously relieved after one week of treatment. After the external liniment is used for one month, the lumbar vertebra disease never recurs.
Patient five: fouxx, male, 50 years old, now xxx mining, Inc. hosts the Wu office. In 2017, the inventor is very painful because the person can not do work due to lumbago. The lumbar disc herniation is confirmed by nuclear magnetic examination in hospitals, and the external liniment (the traditional Chinese medicine composition prepared in example 1) is used, so that the lumbar pain is obviously relieved after one week of treatment. After the external liniment is used for one month, the lumbar vertebra disease never recurs.
The patient six: wang xx, male, 57 years old, now working at the public office in xxx county. The lumbar hyperosteogeny is diagnosed by the hospital examination in 2008, and the lumbago can not sit and stand for a long time, which brings great influence to the work of the user and brings extreme pain to the physical spirit of the user due to intolerable pain. With the external liniment (the traditional Chinese medicine composition prepared in example 1), the lumbar pain is obviously relieved after one week of treatment. After the external liniment is used for one month, the lumbar vertebra disease never recurs.
In summary, according to the invention, wild mugwort leaf, ginger, gastrodia elata, pseudo-ginseng, polygonum multiflorum and safflower are mainly adopted, pain relieving, collateral activating, resuscitation inducing, tendon relaxing and pain relieving effects are achieved, musk is used for bone penetration, stasis removing and pain relieving, realgar is used for detoxifying and sterilizing, effects of activating blood circulation, dredging channels, relieving swelling and pain are achieved, vinegar is used for decocting and eliminating self toxin of the used medicines, and good effects of the used medicines are fully dissolved in liquid. Has good treatment effect on cerebral ischemia, headache, dizziness, numbness of limbs, severe pain of lumbar vertebra and shoulder joints, arthritis and rheumatism pain caused by lumbar disc herniation and cervical hyperplasia. Secondly, the vinegar is used as a solvent to decoct the traditional Chinese medicine raw materials, so that the active ingredients of the raw materials are dissolved out, the percutaneous absorption of the traditional Chinese medicine composition is promoted, and the use value is high. Thirdly, when the traditional Chinese medicine composition is used as an external liniment, on one hand, the external liniment can not leave scars on the skin surface of a patient when in use, and on the other hand, the external liniment is convenient for the patient to use in various environments and is better in use.
The embodiments described above are some, but not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Claims (10)
1. A preparation method of a traditional Chinese medicine composition for treating hyperosteogeny and lumbar muscle strain is characterized by comprising the following steps:
weighing the raw materials according to the weight, slicing and mixing to prepare a mixture; mixing the mixture with ethanol solution, soaking for 10min-30min, adding edible vinegar solution, decocting for three times, performing solid-liquid separation, and mixing medicinal liquids to obtain the Chinese medicinal composition;
the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 40-50 parts of folium artemisiae argyi, 20-30 parts of rhizoma zingiberis, 15-20 parts of rhizoma gastrodiae, 8-15 parts of pseudo-ginseng, 10-20 parts of polygonum multiflorum, 10-15 parts of musk, 5-10 parts of realgar, 5-10 parts of borneol and 5-10 parts of saffron.
2. The preparation method of claim 1, wherein the Chinese medicinal composition further comprises the following raw materials in parts by weight: 4-6 parts of ligusticum wallichii, 6-8 parts of eucommia ulmoides, 1-3 parts of kava root and 2-4 parts of mistletoe.
3. The preparation method of claim 2, wherein the Chinese medicinal composition further comprises the following raw materials in parts by weight: 5-8 parts of pyrola, 12-20 parts of radish seed, 8-15 parts of cynomorium songaricum and 3-4 parts of radix angelicae pubescentis.
4. The preparation method of claim 3, wherein the traditional Chinese medicine composition comprises the following raw materials in parts by weight: 45 parts of folium artemisiae argyi, 25 parts of rhizoma zingiberis, 18 parts of rhizoma gastrodiae, 12 parts of pseudo-ginseng, 15 parts of polygonum multiflorum, 13 parts of musk, 8 parts of realgar, 7 parts of borneol, 8 parts of saffron, 5 parts of ligusticum wallichii, 7 parts of eucommia ulmoides, 2 parts of shanshu ginger root, 3 parts of mistletoe, 6 parts of pyrola, 18 parts of semen raphani, 10 parts of cynomorium songaricum and 3 parts of radix angelicae pubescentis.
5. The preparation method according to claim 1, wherein the vinegar solution is added for the first time, and then the mixture is decocted at 100-120 ℃ for 6-8 hours.
6. The preparation method according to claim 5, wherein the ratio of the amount of the first vinegar solution to the amount of the second vinegar solution to the amount of the third vinegar solution is (3-5):2:1, and the time for decocting the vinegar after the second vinegar solution is added is 2h to 3h and the time for decocting the vinegar after the third vinegar solution is added is 30min to 40 min.
7. The method according to claim 5 or 6, wherein the volume ratio of vinegar to water in the vinegar solution is (4-5): 1.
8. The method according to claim 7, wherein during the decoction, a distillate is collected and mixed with the liquid medicine.
9. A Chinese medicinal composition for treating hyperosteogeny and lumbar muscle strain as defined in any one of claims 1-8, and its preparation method.
10. An application of a Chinese medicinal composition for treating hyperosteogeny and lumbar muscle strain is characterized in that the Chinese medicinal composition prepared by the preparation method of the Chinese medicinal composition for treating hyperosteogeny and lumbar muscle strain according to any one of claims 1 to 8 is used as an external liniment.
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