CN114588202A - Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and preparation method thereof Download PDFInfo
- Publication number
- CN114588202A CN114588202A CN202210403677.4A CN202210403677A CN114588202A CN 114588202 A CN114588202 A CN 114588202A CN 202210403677 A CN202210403677 A CN 202210403677A CN 114588202 A CN114588202 A CN 114588202A
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- traditional chinese
- chinese medicine
- waist
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Abstract
The invention provides a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pains and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The composition comprises the following raw materials in parts by weight: 15-25 parts of ephedra, 15-25 parts of caulis sinomenii, 15-25 parts of trogopterus dung, 15-25 parts of rhizoma corydalis, 15-25 parts of achyranthes root, 15-25 parts of rhizoma atractylodis, 15-25 parts of frankincense, 15-25 parts of myrrh, 15-25 parts of scorpion, 15-25 parts of stiff silkworm, 15-25 parts of notopterygium root, 15-25 parts of radix angelicae pubescentis, 15-25 parts of cassia twig, 15-25 parts of liquorice, 15-25 parts of salvia miltiorrhiza and 15-25 parts of giant knotweed. The traditional Chinese medicine composition treats rheumatic arthralgia by using ephedra, caulis sinomenii, rhizoma atractylodis, frankincense, myrrh, scorpion, radix angelicae pubescentis, cassia twig, radix salviae miltiorrhizae and polygonum cuspidatum, treats soreness and weakness of waist and knees by using trogopterus dung and rhizoma corydalis, and has good treatment effect on pain in neck, shoulder, waist and legs and rheumatic arthralgia.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain and a preparation method thereof.
Background
Pain in the neck, shoulder, waist and leg, generalized neck and shoulder pain, low back pain, hip pain, leg pain, soreness and numbness of legs and feet, etc., are common symptoms in clinic. However, the disease causes are hidden, the symptoms are not typical, the pain is mild and severe, and sometimes the pain can even be relieved by self, so that the disease causes are not taken into consideration by the majority of patients, and the patients can easily miss the optimal time for treatment. Particularly, the pain in the waist and the lower extremities caused by rheumatism and lumbar disc herniation, although some patients have no obvious symptoms and have wide pain range, the health and the normal work, life, study and labor of people are seriously affected.
Therefore, aiming at the defects, the development of the traditional Chinese medicine composition with good treatment effect has important significance.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pains.
The invention also aims to provide a preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pains, and the method can improve the extraction rate of effective components in the raw materials, is simple to prepare and is suitable for batch production.
The technical problem to be solved by the invention is realized by adopting the following technical scheme.
On one hand, the application provides a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials in parts by weight: 15-25 parts of ephedra, 15-25 parts of caulis sinomenii, 15-25 parts of trogopterus dung, 15-25 parts of rhizoma corydalis, 15-25 parts of achyranthes root, 15-25 parts of rhizoma atractylodis, 15-25 parts of frankincense, 15-25 parts of myrrh, 15-25 parts of scorpion, 15-25 parts of stiff silkworm, 15-25 parts of notopterygium root, 15-25 parts of radix angelicae pubescentis, 15-25 parts of cassia twig, 15-25 parts of liquorice, 15-25 parts of salvia miltiorrhiza and 15-25 parts of giant knotweed.
On the other hand, the application provides a preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which mainly comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 30-40 min, adding dimethyl sulfoxide, stirring, and soaking for 7-12 days to obtain medicinal liquid; adding Myrrha into the above medicinal liquid, soaking for 3-5 days to obtain the above Chinese medicinal composition.
Compared with the prior art, the embodiment of the invention has at least the following advantages or beneficial effects:
on one hand, the application provides a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, the traditional Chinese medicine composition treats rheumatic arthralgia by using ephedra, caulis sinomenii, rhizoma atractylodis, frankincense, myrrh, scorpion, radix angelicae pubescentis, cassia twig, salvia miltiorrhiza and polygonum cuspidatum, dredges blood vessels, activates blood circulation and removes blood stasis by using trogopterus dung and rhizoma corydalis, strengthens muscles and bones by using achyranthes bidentata, treats soreness and weakness of waist and knees, dispels wind and relieves pain by using stiff silkworm, dispels wind and removes dampness by using notopterygium root, and harmonizes the medicines by using liquorice, so that the compatibility is scientific and reasonable, the expected effects of treating neck, shoulder, waist and leg pain and treating rheumatic arthralgia are achieved, and the use value is high.
On the other hand, the application provides a preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, by the method, not only can effective ingredients in the raw materials be extracted, but also the extraction efficiency is high, and meanwhile, the preparation method is simple and convenient, is suitable for batch production, and has high economic benefit.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict. The present invention will be described in detail below with reference to specific examples.
On one hand, the application provides a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials in parts by weight: 15-25 parts of ephedra, 15-25 parts of caulis sinomenii, 15-25 parts of trogopterus dung, 15-25 parts of rhizoma corydalis, 15-25 parts of achyranthes root, 15-25 parts of rhizoma atractylodis, 15-25 parts of frankincense, 15-25 parts of myrrh, 15-25 parts of scorpion, 15-25 parts of stiff silkworm, 15-25 parts of notopterygium root, 15-25 parts of radix angelicae pubescentis, 15-25 parts of cassia twig, 15-25 parts of liquorice, 15-25 parts of salvia miltiorrhiza and 15-25 parts of giant knotweed. The specific effects of each raw material are as follows:
herba ephedrae: pungent, slightly bitter and warm. The lung meridian and the bladder meridian. Induce sweating to relieve exterior syndrome, ventilate lung and relieve asthma, induce diuresis to alleviate edema. Wind-cold exterior excess syndrome, chest distress, cough and asthma, edema due to wind and water, rheumatic arthralgia, deep rooted carbuncle of yin type, and phlegm nodule.
Caulis Sinomenii: bitter and pungent in flavor and mild in nature. Liver and spleen meridians. Has the effects of expelling wind-damp, dredging the channels and collaterals and promoting urination. Can be used for treating rheumatalgia, joint swelling, paralysis and pruritus.
Oletum Trogopterori: has sweet and warm nature and flavor, enters liver channel, has the effects of dredging blood vessels, removing blood stasis and relieving pain, and is mainly used for treating blood stasis, amenorrhea, abdominal pain, traumatic injury, snake and insect bite and other diseases.
Rhizoma corydalis: pungent and bitter with warm nature. Has effects in promoting blood circulation, dispelling blood stasis, regulating qi, and relieving pain. Can be used for treating pain due to qi stagnation and blood stasis, dysmenorrhea, amenorrhea, abdominal mass, puerperal stagnation, traumatic injury, and hernia pain.
Achyranthes root: mild in nature, bitter and sour in taste. It enters liver and kidney meridians. Tonify liver and kidney, strengthen tendons and bones, dispel blood stasis and dredge meridians, and draw blood to descend. It is indicated for soreness and pain of waist and knees, weakness of tendons and bones, amenorrhea, abdominal mass, and vertigo due to liver-yang.
Rhizoma atractylodis: warm in nature, pungent and bitter in flavor. It enters spleen, stomach and liver meridians. Dry dampness and invigorate spleen, dispel wind and cold, improve vision. It is indicated for abdominal distention, diarrhea, edema, beriberi, wind-damp arthralgia, wind-cold type common cold and night blindness.
Frankincense: pungent, bitter and warm. It enters heart, liver and spleen meridians. Promote blood circulation, move qi and alleviate pain, resolve swelling and promote tissue regeneration. Can be used for treating thoracic obstruction, cardialgia, epigastralgia, dysmenorrhea, amenorrhea, puerperal blood stasis, abdominal pain, rheumatic arthralgia, spasm of muscles and tendons, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Myrrh: pungent and bitter in flavor and mild in nature. It enters heart, liver and spleen meridians. Dispel stasis, relieve pain, resolve swelling and promote tissue regeneration. Can be used for treating thoracic obstruction, cardialgia, gastralgia, dysmenorrhea, amenorrhea, puerperal stagnation, abdominal mass, rheumatic arthralgia, traumatic injury, carbuncle, swelling, and pyocutaneous disease.
Whole worm: quan Chong Xie is named quan Xie, pungent and mild. It enters liver meridian. Extinguish wind and relieve spasm, dredge collaterals and alleviate pain, counteract toxic pathogen and dissipate nodulation. Can be used for treating liver wind stirring, spasm, convulsion, infantile convulsion, and apoplexy
Hemiplegia, tetanus, stubborn rheumatism, migraine, sore and ulcer, scrofula.
Stiff silkworm: salty and pungent with mild natures. It enters liver, lung and stomach meridians. Extinguish wind and stop spasm, dispel wind and alleviate pain, resolve phlegm and dissipate nodulation. Can be used for treating liver wind with phlegm,infantile convulsion, tetanus and apoplexy
Headache due to wind-heat, conjunctival congestion, pharyngalgia, pruritus due to rubella, and parotitis.
Notopterygium root: pungent and bitter with warm nature. Enter bladder and kidney meridians. Relieve exterior syndrome, dispel cold, expel wind and remove dampness, and alleviate pain. Can be used for treating wind-cold type common cold, arthralgia due to wind-cold-dampness, neck stiffness, spasm of muscles, soreness of bone joints, edema due to wind-cold, superficial infection, and skin sore.
Radix angelicae pubescentis: pungent and bitter with slightly warm nature. It enters kidney and bladder meridians. Dispel wind and dampness, relieve arthralgia and alleviate pain. Can be used for treating arthralgia due to wind-cold-dampness, lumbago, gonalgia, headache due to wind-cold-yin deficiency, and headache due to wind-cold-dampness.
Cassia twig: pungent, sweet and warm. It enters heart, lung and bladder meridians. Has effects of inducing sweat, expelling pathogenic factors from muscles, warming and dredging channels, supporting yang, regulating qi, and lowering qi. It is commonly used for wind-cold type common cold, abdominal cold pain, amenorrhea due to blood cold, arthralgia, phlegm and fluid retention, edema and palpitation.
Licorice root: has sweet taste and mild nature, enters heart, lung, spleen and stomach channels, has the effects of invigorating spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain and harmonizing other medicines, and is mainly used for treating weakness of spleen and stomach, lassitude and hypodynamia, palpitation and shortness of breath, cough and excessive phlegm, abdominal and limb spasm and pain, carbuncle swelling and sore toxicity, relieving medicine toxicity, strong property and the like.
Red sage root: bitter and slightly cold in taste. It enters heart and liver meridians. Has the effects of activating blood circulation, removing blood stasis, stimulating the menstrual flow, relieving pain, clearing away the heart-fire, relieving restlessness, cooling blood and eliminating carbuncle. Can be used for treating thoracic obstruction, heart pain, abdominal pain, hypochondriac pain, abdominal mass, pain due to pyretic arthralgia, vexation, insomnia, menoxenia, dysmenorrhea, amenorrhea, and pyocutaneous disease with swelling and pain.
Giant knotweed rhizome: slightly bitter in taste and slightly cold in nature. It enters liver, gallbladder and lung meridians. Has the effects of removing dampness by diuresis, eliminating jaundice, clearing away heat and toxic materials, removing blood stasis, relieving pain, relieving cough and eliminating phlegm. Can be used for treating jaundice due to damp-heat pathogen, stranguria with turbid discharge, leukorrhagia, rheumatalgia, carbuncle, swelling, sore, scald due to water and fire, amenorrhea, abdominal mass, contusion injury, and cough due to lung heat.
In conclusion, the traditional Chinese medicine composition treats rheumatic arthralgia by using ephedra, caulis sinomenii, rhizoma atractylodis, frankincense, myrrh, scorpion, radix angelicae pubescentis, cassia twig, salvia miltiorrhiza and polygonum cuspidatum, treats soreness and weakness of waist and knees by using trogopterus dung and rhizoma corydalis to dredge blood vessels and promote blood circulation to remove blood stasis, treats soreness and weakness of waist and knees by using achyranthes bidentata and strengthening bones, dispels wind and relieves pain by using stiff silkworm, dispels wind and removes dampness by using notopterygium root, and harmonizes the medicines by using liquorice, so that the compatibility is scientific and reasonable, the expected effects of treating neck, shoulder, waist and leg pain and treating rheumatic arthralgia are achieved, and the use value is high.
In the application, the composition comprises the following raw materials in parts by weight: 20 parts of ephedra, 20 parts of caulis sinomenii, 20 parts of trogopterus dung, 20 parts of rhizoma corydalis, 20 parts of achyranthes root, 20 parts of rhizoma atractylodis, 20 parts of frankincense, 20 parts of myrrh, 20 parts of scorpion, 20 parts of stiff silkworm, 20 parts of notopterygium root, 20 parts of radix angelicae pubescentis, 20 parts of cassia twig, 20 parts of liquorice, 20 parts of salvia miltiorrhiza and 20 parts of giant knotweed rhizome. The proportion can be suitable for most people, and the universality is stronger.
On the other hand, the application provides a preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pains, which comprises the following steps: the method mainly comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 30-40 min, adding dimethyl sulfoxide, stirring, and soaking for 7-12 days to obtain medicinal liquid; adding Myrrha into the above medicinal liquid, soaking for 3-5 days to obtain the above Chinese medicinal composition.
Specifically, the raw materials are soaked in an ethanol solution, so that water can penetrate through raw material cells, and the alcohol extraction effect of the active ingredients of the raw materials is better. Meanwhile, the raw materials are soaked in dimethyl sulfoxide, so that the stability of each effective component in the raw materials can be enhanced, and the traditional Chinese medicine composition has an analgesic effect, and further has a better treatment effect.
In the application, after the dimethyl sulfoxide is added, ultrasound is carried out in the soaking process, the frequency of the ultrasound is 15-25 kHZ, and the ultrasound time is 1-3 h/day. The raw materials can be damaged by ultrasonic treatment, so that effective components in the raw materials are fully released, and the utilization rate of the traditional Chinese medicine composition is higher.
In the present application, the pretreatment of the raw materials comprises the following steps: washing the raw materials, drying at 45-60 ℃, and then sorting in a winnowing manner to prepare a spare material; grinding the above materials, sieving, and mixing with ethanol solution.
In the application, the standby materials are ground under the pressure of 0.3MPa-0.5MPa and then screened by a 40-80-mesh screen.
In the application, the concentration of the ethanol solution is 70 voL-80 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is (2-3):4, and the mass ratio of the ethanol solution to the ephedra is (35-45): 1.
In the application, the traditional Chinese medicine composition is mixed with a thickening agent, a filling agent and a humectant, and is homogenized to prepare the ointment. The traditional Chinese medicine composition is prepared into paste, so that the convenience and the practicability of the traditional Chinese medicine composition can be improved. Of course, the paste can also be coated on non-woven fabrics to prepare a patch which is convenient for patients to use.
In the application, the thickener is pectin, the filler is kaolin, and the humectant is sorbitol. Pectin is used as a thickening agent to cover the medicines of the traditional Chinese medicine composition and improve the applicability of the paste, for example, the paste can be used in various occasions without worrying about inconvenience caused by excessive traditional Chinese medicine smell. When the kaolin is used as the filler, the traditional Chinese medicine composition has a large volume, a hemostatic effect and a good use effect, and the humectant can make a patient feel good on the skin in the ointment using process and make the patient feel good.
In the application, the mass ratio of the liquid medicine, the pectin, the kaolin and the sorbitol is (8-10) to 4:2: 1.
The features and properties of the present invention are described in further detail below with reference to examples.
Example 1
The embodiment aims to provide a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials: 20g of ephedra, 20g of caulis sinomenii, 20g of trogopterus dung, 20g of rhizoma corydalis, 20g of achyranthes root, 20g of rhizoma atractylodis, 20g of frankincense, 20g of myrrh, 20g of scorpion, 20g of stiff silkworm, 20g of notopterygium root, 20g of radix angelicae pubescentis, 20g of cassia twig, 20g of liquorice, 20g of salvia miltiorrhiza and 20g of giant knotweed rhizome.
The preparation method of the composition comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 35min, adding dimethyl sulfoxide, stirring, soaking for 10 days to obtain medicinal liquid, and performing ultrasonic treatment at frequency of 20kHz for 2 h/day; adding Myrrha into the above medicinal liquid, soaking for 4 days to obtain the above Chinese medicinal composition. Wherein the concentration of the ethanol solution is 75 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is 5:8, and the mass ratio of the ethanol solution to the ephedra is 40: 1.
The pretreatment steps of the raw materials are as follows: washing the raw materials, drying at 50 deg.C, and air separating to obtain a product; grinding the above materials under 0.4MPa, sieving with 60 mesh sieve, and mixing with ethanol solution.
Example 2
The embodiment aims to provide a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials: 20g of ephedra, 20g of caulis sinomenii, 20g of trogopterus dung, 20g of rhizoma corydalis, 20g of achyranthes root, 20g of rhizoma atractylodis, 20g of frankincense, 20g of myrrh, 20g of scorpion, 20g of stiff silkworm, 20g of notopterygium root, 20g of radix angelicae pubescentis, 20g of cassia twig, 20g of liquorice, 20g of salvia miltiorrhiza and 20g of giant knotweed rhizome.
The preparation method of the composition comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 35min, adding dimethyl sulfoxide, stirring, soaking for 10 days to obtain medicinal liquid, and performing ultrasonic treatment at frequency of 20kHz for 2 h/day; adding Myrrha into the above medicinal liquid, soaking for 4 days to obtain the above Chinese medicinal composition. Wherein the concentration of the ethanol solution is 75 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is 5:8, and the mass ratio of the ethanol solution to the ephedra is 40: 1.
The pretreatment steps of the raw materials are as follows: washing the raw materials, drying at 50 deg.C, and air separating to obtain a product; grinding the above materials under 0.4MPa, sieving with 60 mesh sieve, and mixing with ethanol solution.
Mixing the above Chinese medicinal composition with thickener, filler and humectant, homogenizing under 0.2MPa, and making into unguent. The thickener is gelatin, the filler is microcrystalline cellulose, and the humectant is glycerin.
Example 3
The embodiment aims to provide a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials: 20g of ephedra, 20g of caulis sinomenii, 20g of trogopterus dung, 20g of rhizoma corydalis, 20g of achyranthes root, 20g of rhizoma atractylodis, 20g of frankincense, 20g of myrrh, 20g of scorpion, 20g of stiff silkworm, 20g of notopterygium root, 20g of radix angelicae pubescentis, 20g of cassia twig, 20g of liquorice, 20g of salvia miltiorrhiza and 20g of giant knotweed rhizome.
The preparation method of the composition comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 35min, adding dimethyl sulfoxide, stirring, soaking for 10 days to obtain medicinal liquid, and performing ultrasonic treatment at frequency of 20kHz for 2 h/day; adding Myrrha into the above medicinal liquid, soaking for 4 days to obtain the above Chinese medicinal composition. Wherein the concentration of the ethanol solution is 75 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is 5:8, and the mass ratio of the ethanol solution to the ephedra is 40: 1.
The pretreatment steps of the raw materials are as follows: washing the raw materials, drying at 50 deg.C, and air separating to obtain a product; grinding the above materials under 0.4MPa, sieving with 60 mesh sieve, and mixing with ethanol solution.
Mixing the above Chinese medicinal composition with thickener, filler and humectant, homogenizing under 0.2MPa, and making into unguent. The thickening agent is pectin, the filling agent is kaolin, the humectant is sorbitol, and the mass ratio of the traditional Chinese medicine composition, the pectin, the kaolin and the sorbitol is 9:4:2: 1.
Example 4
The embodiment aims to provide a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials: 15g of ephedra, 15g of caulis sinomenii, 15g of trogopterus dung, 15g of rhizoma corydalis, 15g of achyranthes root, 15g of rhizoma atractylodis, 15g of frankincense, 15g of myrrh, 15g of scorpion, 15g of stiff silkworm, 15g of notopterygium root, 15g of radix angelicae pubescentis, 15g of cassia twig, 15g of liquorice, 15g of salvia miltiorrhiza and 15g of giant knotweed rhizome.
The preparation method of the composition comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 30min, adding dimethyl sulfoxide, stirring, soaking for 7 days to obtain medicinal liquid, and performing ultrasonic treatment at ultrasonic frequency of 15kHZ for 1 h/day; adding Myrrha into the above medicinal liquid, soaking for 3 days to obtain the above Chinese medicinal composition. Wherein the concentration of the ethanol solution is 70 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is 1:2, and the mass ratio of the ethanol solution to the ephedra is 35: 1.
The pretreatment steps of the raw materials are as follows: washing the raw materials, drying at 45 ℃, and then sorting in a winnowing manner to prepare a spare material; grinding the above materials under 0.3MPa, sieving with 40 mesh sieve, and mixing with ethanol solution.
Mixing the above Chinese medicinal composition with thickener, filler and humectant, homogenizing under 0.2MPa, and making into unguent. The thickening agent is pectin, the filling agent is kaolin, the humectant is sorbitol, and the mass ratio of the traditional Chinese medicine composition, the pectin, the kaolin and the sorbitol is 8:4:2: 1.
Example 5
The embodiment aims to provide a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, which comprises the following raw materials: 25g of ephedra, 25g of caulis sinomenii, 25g of trogopterus dung, 25g of rhizoma corydalis, 25g of achyranthes root, 25g of rhizoma atractylodis, 25g of frankincense, 25g of myrrh, 25g of scorpion, 25g of stiff silkworm, 25g of notopterygium root, 25g of radix angelicae pubescentis, 25g of cassia twig, 25g of liquorice, 25g of salvia miltiorrhiza and 25g of giant knotweed rhizome.
The preparation method of the composition comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 40min, adding dimethyl sulfoxide, stirring, soaking for 12 days to obtain medicinal liquid, and performing ultrasonic treatment at ultrasonic frequency of 25kHZ for 3 h/day; adding Myrrha into the above medicinal liquid, soaking for 5 days to obtain the above Chinese medicinal composition. Wherein the concentration of the ethanol solution is 80 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is 3:4, and the mass ratio of the ethanol solution to the ephedra is 45: 1.
The pretreatment steps of the raw materials are as follows: washing the raw materials, drying at 50 ℃, and then sorting in a winnowing manner to prepare a spare material; grinding the above materials under 0.5MPa, sieving with 80 mesh sieve, and mixing with ethanol solution.
Mixing the above Chinese medicinal composition with thickener, filler and humectant, homogenizing under 0.2MPa, and making into unguent. The thickening agent is pectin, the filling agent is kaolin, the humectant is sorbitol, and the mass ratio of the traditional Chinese medicine composition, the pectin, the kaolin and the sorbitol is 10:4:2: 1.
Examples of effects
General data: 160 volunteer patients were collected, the age range was 34-68 years, the average age was (56 ± 2.687) years, the course of disease was 1-6.5 years, and referring to the syndrome differentiation scoring standard of traditional Chinese medicine (see table 1), the volunteer patients were divided into 5 groups according to their symptom degrees, which were example 1 to example 5 groups, and the treatment effects of the patients were observed by using the drugs prepared in examples 1-5, respectively, as shown in table 2. In addition, the statistical analysis shows that p is more than 0.05 and is comparable. The average score difference for each group of patients ranged from 0 to 3,
among the volunteer patients, 72 people suffered from neck and shoulder pain, 21 people suffered from waist pain, 18 people suffered from knee joint pain and 49 people suffered from leg pain. The trial effect is shown in table 2.
The using method comprises the following steps: the Chinese medicinal composition and the ointment prepared in examples 1 to 5 were applied externally, and the effect was observed 7 days after application. The dosage of each group of volunteer patients was the same.
Patient inclusion criteria: (1) the symptoms of neck, shoulder, waist and leg pain, swelling and limited movement of different degrees exist, and are in accordance with the clinical diagnosis standard of the neck, shoulder, waist and leg pain; (2) patients and their family members participate voluntarily.
Patient exclusion criteria: (1) other analgesic treatments have been previously received; (2) merging malignant tumors; (3) there is a severe skin disease; (4) gestation or lactation; (5) there are severe cognitive, psychiatric disorders.
Evaluation criteria: (1) the effect is shown: the pain of neck, shoulder, waist and leg of the patient disappears or is obviously improved after the treatment, and the normal work and life of the patient are not influenced; (2) the method has the following advantages: the symptoms of neck, shoulder, waist and leg pain of the patient are improved to a certain extent after the treatment is finished, and the influence on the normal work and life of the patient is slight; (3) and (4) invalidation: the pain of neck, shoulder, waist and leg of the patient is not improved or aggravated after the treatment is finished, and the influence on the normal work and life of the patient is serious.
Effective rate% ((number of effective persons + number of effective persons) × 100%/number of participating persons).
TABLE 1 Chinese medicine syndrome differentiation and judgment criteria
TABLE 2 therapeutic Effect
| Grouping | The number of participating persons | Number of effective people | Number of effective persons | Number of invalid persons | Effective rate of |
| EXAMPLE 1 group | 28 persons | 13 persons | 13 persons | 2 persons | 92.86％ |
| EXAMPLE 2 group | 34 persons | 16 persons | 14 persons | 4 persons | 88.24％ |
| EXAMPLE 3 group | 34 persons | 15 persons | 17 persons | 2 persons | 94.12％ |
| EXAMPLE 4 group | 29 persons | 11 persons | 13 persons | 5 persons | 82.76％ |
| EXAMPLE 5 group | 35 people | 15 persons | 18 persons | 2 persons | 94.29％ |
As can be seen from the table 2, the traditional Chinese medicine composition and the ointment prepared from the raw materials and the preparation method provided by the application have good treatment effect on neck, shoulder, waist and leg pains, and the effective rate is over 80%. According to the review, the traditional Chinese medicine compositions prepared in the examples 2 to 5 have the advantage of convenient carrying in the using process, the traditional Chinese medicine smell is lighter in the using process of the examples 3 to 5, and meanwhile, the pain relieving effect of the example 5 is quicker.
In conclusion, the application provides a traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain, the traditional Chinese medicine composition treats rheumatic arthralgia by using ephedra, caulis sinomenii, rhizoma atractylodis, frankincense, myrrh, scorpion, radix angelicae pubescentis, cassia twig, salvia miltiorrhiza and polygonum cuspidatum, treats soreness and weakness of waist and knees by using trogopterus dung and rhizoma corydalis, dredges blood vessels, promotes blood circulation and removes blood stasis, strengthens muscles and bones by using achyranthes bidentata, treats soreness and weakness of waist and knees by using stiff silkworm to dispel wind and relieve pain, dispels wind and removes dampness by using notopterygium root, and harmonizes the medicines by using liquorice, so that the compatibility is scientific and reasonable, the expected effects of treating neck, shoulder, waist and leg pain and treating rheumatic arthralgia are achieved, and the use value is high. In addition, the application provides a preparation method of the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pains, the method can be used for extracting effective components in the raw materials, the extraction efficiency is high, meanwhile, the preparation is simple and convenient, the traditional Chinese medicine composition is suitable for batch production, and the economic benefit is high.
The embodiments described above are some, not all embodiments of the invention. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Claims (10)
1. A traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain is characterized by comprising the following raw materials in parts by weight: 15-25 parts of ephedra, 15-25 parts of caulis sinomenii, 15-25 parts of trogopterus dung, 15-25 parts of rhizoma corydalis, 15-25 parts of achyranthes root, 15-25 parts of rhizoma atractylodis, 15-25 parts of frankincense, 15-25 parts of myrrh, 15-25 parts of scorpion, 15-25 parts of stiff silkworm, 15-25 parts of notopterygium root, 15-25 parts of radix angelicae pubescentis, 15-25 parts of cassia twig, 15-25 parts of liquorice, 15-25 parts of salvia miltiorrhiza and 15-25 parts of giant knotweed.
2. The traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain according to claim 1, which is prepared from the following raw materials in parts by weight: 20 parts of ephedra, 20 parts of caulis sinomenii, 20 parts of trogopterus dung, 20 parts of rhizoma corydalis, 20 parts of achyranthes root, 20 parts of rhizoma atractylodis, 20 parts of frankincense, 20 parts of myrrh, 20 parts of scorpion, 20 parts of stiff silkworm, 20 parts of notopterygium root, 20 parts of radix angelicae pubescentis, 20 parts of cassia twig, 20 parts of liquorice, 20 parts of salvia miltiorrhiza and 20 parts of giant knotweed rhizome.
3. A method for preparing the traditional Chinese medicine composition for treating neck, shoulder, waist and leg pain according to claim 1 or 2, which comprises the following steps:
pretreating raw materials, soaking the raw materials except Myrrha in ethanol solution for 30-40 min, adding dimethyl sulfoxide, stirring, and soaking for 7-12 days to obtain medicinal liquid; and adding myrrh into the liquid medicine, and soaking for 3 to 5 days to obtain the traditional Chinese medicine composition.
4. The preparation method according to claim 3, characterized in that after the dimethyl sulfoxide is added, ultrasound is carried out during the soaking process, the frequency of the ultrasound is 15-25 kHZ, and the ultrasound time is 1-3 h/day.
5. The method of claim 3, wherein the step of pretreating the feedstock comprises:
washing the raw materials, drying at 45-60 ℃, and then sorting in a winnowing manner to prepare a spare material; grinding the standby materials, sieving, and mixing with ethanol solution.
6. The method of claim 5, wherein the stock is ground under a pressure of 0.3MPa to 0.5MPa and then screened through a 40 mesh to 80 mesh screen.
7. The preparation method according to claim 3, wherein the concentration of the ethanol solution is 70 voL-80 voL%, the mass ratio of the ethanol solution to the dimethyl sulfoxide is (2-3):4, and the mass ratio of the ethanol solution to the ephedra is (35-45): 1.
8. The preparation method according to claim 3, wherein the Chinese medicinal composition is mixed with a thickener, a filler and a humectant, and is homogenized to prepare an ointment.
9. The method of claim 8, wherein the thickener is pectin, the filler is kaolin, and the humectant is sorbitol.
10. The preparation method of claim 9, wherein the mass ratio of the traditional Chinese medicine composition, the pectin, the kaolin and the sorbitol is (8-10) to 4:2: 1.
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| CN103690605A (en) * | 2013-12-12 | 2014-04-02 | 王胜祥 | Traditional Chinese medicine preparation for treating rheumatism |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103690605A (en) * | 2013-12-12 | 2014-04-02 | 王胜祥 | Traditional Chinese medicine preparation for treating rheumatism |
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| Title |
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| 张秀良: "《中老年自我治病奇效方大全》", 31 July 2016, 中医古籍出版社 * |
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