CN113018399A - Chinese herbal medicine product for treating calendar-joint wind, gout and condyle pain - Google Patents

Abstract

A Chinese herbal medicine product for treating the wind, gout and joint pain of the Alexandrium, belongs to the field of traditional Chinese medicines, the Chinese herbal medicine comprises lily, bunge cherry seed, rhizoma corydalis processed with vinegar, radix stephaniae tetrandrae, erythrina bark, impatiens balsamina, garden balsam stem, futokadsura stem, sargentgloryvine stem, achyranthes root, myrrh processed with vinegar, and the auxiliary materials are dextrin, the weight ratio of the dextrin to the lily to the bunge cherry seed to the corydalis processed with vinegar to the radix Stephaniae Tetrandrae to the erythrina bark to the garden balsam stem to the futokadsura stem to the achyranthes root to the myrrh processed with vinegar is 100: 15-25: 20-30: 15-20: 20-30: 15-30, the invention aims to eliminate or relieve the pain caused by the wind, the gout, the inflammation of the Alexandrium and the joint by expelling wind, eliminating cold, clearing heat, reducing phlegm, can strengthen body constitution and relieve various diseases.

Description

Chinese herbal medicine product for treating calendar-joint wind, gout and condyle pain

Technical Field

The invention relates to a Chinese herbal medicine product, in particular to a Chinese herbal medicine product for treating almanac, gout and condyle pain, and belongs to the field of traditional Chinese medicines.

Background

Gout, known in traditional Chinese medicine as almanac wind, is a common and complex type of arthritis. Patients with the traditional arthritis often have sudden joint pain at night, acute morbidity, serious pain, edema, red swelling and inflammation at joints, pain feeling is slowly relieved until the pain disappears, swelling deformity and severe pain of joints of two feet, wrists and toes exist, and some patients are accompanied by heart damage and have different durations for days or weeks. When pain occurs, the patient wakes up in a deep sleep in the middle of the night, and the patient describes the pain feeling as if the big toe is burned. The most frequently encountered joints are the big toes (medical term: first metatarsal), but the encountered joints are not limited thereto, but are also commonly found in joints of the hand, knee, elbow, and the like. The affected joints are red, swollen and inflamed finally, tissues become soft after edema, activities are limited, and daily life is affected finally.

The symptoms of the wind in the past are wind-cold-dampness arthralgia, stagnation of qi and yin, deficiency of blood and body weakness, heat transformation after long-term use, the pain of the wind in the past is similar to the symptoms of rheumatoid diseases, the wind is treated firstly, the blood is treated automatically after the blood is blown out, heat is removed, evil is eliminated, yin is nourished, wind is dispelled, yin is nourished, heat is cleared, qi is benefited, blood is enriched, spleen is invigorated, dampness is removed, yin is astringed, blood is nourished, and chronic symptoms such as gout stones, ankylosis or malformation of joints, damage of kidney parenchyma. Gout is not a single disease but a syndrome, and many diseases cause elevated blood uric acid and are deposited on joints, connective tissues and kidneys to cause damage to these parts.

The gout in western medicine is chronic crystal arthritis caused by deposition of monosodium urate (MSU), and is used as the chronic crystal arthritis, which affects obstruction of muscles, meridians and qi and blood along with continuous development of arthritis, is accompanied by physical weakness, poor resistance, kidney lesion, heart loss and kidney damage, and further complicated with a plurality of metabolic diseases such as hyperlipidemia, hypertension, diabetes, lipid metabolism disorder and the like.

In addition, the western medicine considers that gout is directly related to hyperuricemia caused by purine metabolic disorder and/or reduction of uric acid excretion, and belongs to the category of metabolic rheumatism.

Tophus is a yellowish or white bulge or vegetation of varying size that is hard in texture and resembles a stone. Tophus formed on various parts of the body, especially four limbs, not only seriously affects the appearance of the limbs, but also can cause joint deformity, dysfunction, nerve compression, skin ulceration and prolonged unhealed sinus.

The medicines for treating gout mainly comprise nonsteroidal anti-inflammatory drugs and glucocorticoids, but the current methods for treating gout by medicines are less. In contrast, the traditional Chinese medicine has small side effect and obvious effect in treatment.

Rheumatoid diseases are caused by the heterozygosis of wind, cold, dampness and heat, mainly due to the deficiency of healthy qi and the repeated affection of wind, cold, dampness and heat. Such as: the pathogenic wind-cold-dampness attacking the human body due to dampness, rain caused by wading, drastic change of climate and alternate cold and heat can cause wind-cold-dampness attacking the human body, and then the pathogenic wind-cold-dampness is injected into the channels and collaterals and finally stays in joints, muscles and muscle cavities to cause the qi and blood to be blocked to form the rheumatoid arthritis.

The traditional Chinese medicine composition is characterized by multiple joints, symmetrical and invasive arthritis of small joints of hands and feet, and the multiple joints are symmetrical joint synovitis and are often accompanied by the involvement of external organs of joints and the positive of serum rheumatoid factors, so that the joint deformity and the function loss are caused. The rheumatoid arthritis is persistent and difficult to cure, and the pain is spread over a plurality of joints of the whole body.

The common ephedra, gout, rheumatoid arthritis, rheumatic arthritis and bone joint pain are generally caused by wind cold and rheumatism, and the internal organs of the human body are affected finally due to qi and blood deficiency and meridian obstruction. Western medicine for treating the gout, the rheumatoid arthritis, the rheumatic arthritis and the joint pain can temporarily relieve the pain, but cannot remove the root, so that the symptoms are eliminated, the treatment time is long, the medicine needs to be given according to the symptoms, and particularly, the medicine cannot be spread and developed, and if the symptom does not permeate into the internal organs, the symptom is difficult to cure.

The common characteristic of the Alexandrium perfoliatum, gout, rheumatoid arthritis and condyle pain is pain at joint parts, the traditional Chinese medicine of the Alexandrium perfoliatum, the rheumatoid arthritis, the rheumatic arthritis and the condyle pain is considered to be caused by wind, cold and heat, and the treatment of symptoms of the Alexandrium perfoliatum, the gout, the rheumatoid arthritis, the rheumatic arthritis and the condyle pain is a longer treatment process.

Disclosure of Invention

Aiming at the real problem that western medicines cannot remove roots temporarily in the process of treating the almanac wind, the gout, the rheumatoid arthritis, the rheumatic arthritis and the condyle pain, the invention provides a Chinese herbal medicine product for treating the almanac wind, the gout and the condyle pain, and aims to eliminate or relieve the pain caused by the almanac wind, the gout, the condyle inflammation and the like by dispelling wind, dispelling cold, removing dampness, clearing heat, reducing phlegm, dispelling nodules and tonifying deficiency, improve the immunity, strengthen the physique and simultaneously relieve various concurrent diseases.

The specific technical scheme of the invention is as follows: a Chinese herbal medicine product for treating Alternaria sinensis, gout and joint pain comprises lily, bunge cherry seed, vinegar-processed corydalis tuber, radix stephaniae tetrandrae, erythrina bark, garden balsam stem, futokadsura stem, chinaroot greenbrier, achyranthes and vinegar-processed myrrh, and dextrin is used as an auxiliary material, wherein the weight parts of the dextrin, the lily, the bunge cherry seed, the vinegar-processed corydalis tuber, the radix stephaniae tetrandrae, the bark of erythrina, the garden balsam stem, the futokadsura stem, the chinaroot greenbrier, the achyranthes and the vinegar-processed myrrh are respectively 100: 15-25: 20-30: 15-25: 20-30: 15-30;

further, the preparation method of the Chinese herbal medicine product for treating the calendar joint wind, the gout and the condyle pain comprises the following steps:

1) according to the weight of the medicine, the lily, the bunge cherry seed, the vinegar rhizoma corydalis, the radix stephaniae tetrandrae, the erythrina bark, the impatiens balsamina, the futokadsura stem, the smilax, the achyranthes, the vinegar myrrh = 100: 15-25: 20-30: 15-20: 20-30: 15-25: 20-30: 15-30 are respectively screened and weighed according to the weight part ratio of the dextrin, the lily, the bunge cherry seed, the vinegar rhizoma corydalis, the radix stephaniae tetrandrae, the erythrina bark, the impatiens balsamina, the futokadsura stem, the smilax, the achyranthes, the vinegar myrrh and the dextrin;

2) mixing the weighed medicinal materials, putting the mixture into an extraction pot, adding water which is 5-12 times of the total weight of the medicinal materials into the medicinal materials, soaking for 60 minutes, extracting by using ultrasonic waves at the temperature of 100 ℃, extracting twice by using the ultrasonic waves, and heating for 100 minutes each time;

3) filtering the medicinal liquid with a pipeline centrifuge to remove residue, mixing the two extractive solutions, and mixing;

4) vacuum concentrating the mixed extractive solution at low temperature with double-effect vacuum concentrator to obtain soft extract;

5) cooling the concentrated soft extract with a freeze dryer at-40 deg.C, and freezing to obtain dry extract;

6) crushing the dry paste into 80-mesh fine powder, filling the fine powder into bags, packing the bags in a sealing mode, or pressing the dry paste powder into tablets and packing the tablets in a sealing mode, or pressing the dry paste powder into 100-300 times of water, preparing oral liquid and syrup, filling and sterilizing.

The invention has the following positive effects: the medicine for expelling wind, dispelling cold and removing dampness can remove wind-cold-dampness arthralgia in a body, can reduce invasion of wind-cold-dampness evil to a human body, can expel wind, promote qi circulation, dispel dampness, activate blood, clear away the heart-fire, tranquilize the mind, tonify middle-jiao and qi, can clear away heat and toxic materials, cool blood, stop bleeding, strengthen the spleen and stomach, further moisten the lung, smooth intestines, expel qi and promote diuresis, realize rheumatism, dredge channels and collaterals, regulate qi, activate blood, promote blood circulation, remove blood stasis, stop bleeding, eliminate edema, reduce rheumatic arthralgia and damp-heat limb pain, meanwhile, promote diuresis by descending qi, moisten the lung, soothe the heart, soothe the nerves, tonify the middle-jiao and qi, moisten the lung, relieve cough, eliminate various inflammations in six internal organs, enhance the function of an endogenous anti-pain system, enable the body function to be strong, reduce invasion of the external environment to the body, further, reduce blood vessel dilation, promote heart, Cold dispelling, dampness eliminating, heat clearing away, phlegm eliminating, nodule eliminating, deficiency tonifying, pain relieving, immunity improving, body constitution improving, and cardiovascular and cerebrovascular diseases such as hypertension and hyperlipemia relieving.

Detailed Description

The following examples further illustrate specific embodiments of the present invention.

First, the efficacy of the various herbs used in the present invention and the commonly used diseases to be treated are described in common.

Lily: has effects in moistening lung, relieving cough, clearing away heart-fire, tranquilizing mind, invigorating middle warmer, invigorating qi, clearing away heat and toxic materials, cooling blood, stopping bleeding, invigorating spleen, and regulating stomach function. The main treatment is as follows: pulmonary tuberculosis, chronic cough, expectoration, phlegm blood, cardiopalmus, severe palpitation, insomnia, dreaminess, dysphoria, cardialgia, pharyngitis, stomach ache due to deficiency of stomach yin, constipation, edema, carbuncle, suppurative sore, loempe, puerperal hemorrhage, abdominal distention, and general pain.

The Chinese dwarf cherry seeds: has the efficacies of moistening lung and intestine, promoting qi circulation and inducing diuresis, and is mainly used for treating: can be used for treating qi stagnation in large intestine, dryness, difficulty in micturition, abdominal edema, edema of limbs, and tinea pedis.

Vinegar rhizoma corydalis: has the efficacies of promoting blood circulation, promoting qi circulation and relieving pain, and has the main treatment effects: the corydalis tuber also has the functions of tranquilizing, expanding blood vessels, resisting arrhythmia and ulcer, inhibiting gastric acid secretion, enhancing a new action mechanism of endogenous anti-pain system functions, having good analgesic and sedative effects, and also having the functions of tranquilizing, expanding blood vessels, resisting arrhythmia and ulcer, inhibiting gastric acid secretion and the like. The main treatment is as follows: pain due to qi stagnation and blood stasis.

Stephania tetrandra: has the efficacies of dispelling wind, eliminating dampness, relieving pain and promoting diuresis, and has the main treatment effects: rheumatic arthralgia, damp-heat limb pain, edema, dysuria, beriberi and damp swelling.

Erythrina bark: has effects of relieving pain, diminishing inflammation, dispelling pathogenic wind, activating qi-flowing, eliminating dampness and promoting blood circulation, and can be used for treating gastritis, nephritis and rheumatalgia by treating root bark, and also can be used for external application on incised wound. Dispel wind-damp, unblock collaterals and kill parasites. It is used to treat rheumatic arthralgia, dysentery, toothache, and scabies.

Garden balsam stem: has the functions of dispelling wind and dampness, promoting blood circulation to disperse blood clots and eliminating toxic matter. The main treatment is as follows: rheumatism, arthralgia, traumatic injury, swelling and pain, amenorrhea, dysmenorrhea, carbuncle, sore, erysipelas, fungal infection of hand and foot, snake bite, etc.

Caulis piperis futokadsurae: has effects of dispelling pathogenic wind and removing dampness, dredging channels and collaterals, and regulating qi-flowing. The main treatment is as follows: arthralgia due to wind-cold-dampness, arthralgia, spasm of muscles and tendons, traumatic injury, asthma, and chronic cough.

And (3) smilax: has the effects of reducing blood sugar, resisting inflammation, relieving pain, resisting bacteria and resisting tumor, and is mainly used for treating: stranguria with turbid urine, leukorrhagia, rheumatalgia, traumatic injury, furuncle, carbuncle, and swelling. It can also be used for treating common cold, fever, tonsillitis, dyspepsia, urinary tract infection, nephritis, psoriasis, rectal prolapse, nasopharyngeal carcinoma, gastric cancer, rectal cancer, and cervical cancer.

Achyranthes root: has the effects of removing blood stasis, relieving pain, promoting blood circulation, dredging channels, tonifying liver and kidney, especially for waist soreness, leg weakness, radix cyathulae partial stagnation of blood stasis, dredging channels, treating blood stasis, amenorrhea and the like, and has the efficacy of reducing blood pressure, and the main treatment is as follows: soreness and weakness of bones and muscles, pain of waist and knees, blood stasis due to amenorrhea, and pain due to rheumatism due to deficiency of liver and kidney.

Vinegar myrrh: is not soaked in vinegar, and the main effects of the myrrh are activating blood circulation to dissipate blood stasis, removing blood stasis to stop bleeding, reducing swelling and promoting granulation, and is used for treating diseases such as chest stuffiness and pains, epigastric pain, dysmenorrheal amenorrhea, postpartum stasis, abdominal mass and pain, rheumatic arthralgia, traumatic injury, carbuncle, swelling, sore and ulcer and the like.

The preparation of the Chinese herbal medicine is carried out according to the following steps before the treatment,

1) according to the weight of the medicine, the lily, the bunge cherry seed, the vinegar rhizoma corydalis, the radix stephaniae tetrandrae, the erythrina bark, the impatiens balsamina, the futokadsura stem, the smilax, the achyranthes, the vinegar myrrh = 100: 15-25: 20-30: 15-20: 20-30: 15-25: 20-30: 15-30 are respectively screened and weighed according to the weight part ratio of the dextrin, the lily, the bunge cherry seed, the vinegar rhizoma corydalis, the radix stephaniae tetrandrae, the erythrina bark, the impatiens balsamina, the futokadsura stem, the smilax, the achyranthes, the vinegar myrrh and the dextrin;

2) mixing the weighed medicinal materials, putting the mixture into an extraction pot, adding water which is 5-12 times of the total weight of the medicinal materials into the medicinal materials, soaking for 60 minutes, extracting by using ultrasonic waves at the temperature of 100 ℃, extracting twice by using the ultrasonic waves, and heating for 100 minutes each time;

3) filtering the medicinal liquid with a pipeline centrifuge to remove residue, mixing the two extractive solutions, and mixing;

4) vacuum concentrating the mixed extractive solution at low temperature with double-effect vacuum concentrator to obtain soft extract;

5) cooling the concentrated soft extract with a freeze dryer at-40 deg.C, and freezing to obtain dry extract;

6) crushing the dry paste into 80-mesh fine powder, filling the fine powder into bags, packing the bags in a sealing mode, or pressing the dry paste powder into tablets and packing the tablets in a sealing mode, or pressing the dry paste powder into 100-300 times of water, preparing oral liquid and syrup, filling and sterilizing.

In the treatment process of this example, a test was conducted with 4 months as a treatment course, and the following are clinical examples using the present Chinese herbal medicine:

in the table, all the patients had different degrees of pain in the joints of the feet, the joints of the legs, etc. before treatment, and all the patients were diagnosed with the pain in the joint of the calendar, gout, rheumatoid arthritis, and joint pain.

Prolonged treatment means that a person who is not completely cured and is in a good condition is treated for another half treatment course.

And (3) curing: if the pain disappears and the walking is not uncomfortable, the test result enters normal.

Improvement: occasional pain, much improved walking and pre-treatment, essentially no discomfort, but test results were close to normal range.

The invention can realize the medicine for expelling wind, dispelling cold and removing dampness by utilizing the combination of the radix stephaniae tetrandrae, the garden balsam stem and the futokadsura stem, can remove wind-cold-dampness arthralgia in a body, can reduce the invasion of wind-cold-dampness evil to the human body, and simultaneously can realize the effects of expelling wind, promoting the circulation of qi, eliminating dampness, promoting blood circulation, clearing away the heart-fire, soothing the nerves, dredging the channels and collaterals, regulating qi, promoting blood circulation, removing blood stasis, stopping bleeding, tonifying middle-jiao and replenishing qi by utilizing the combination of the lily, the bunge cherry seed and the radix stephaniae tetrandrae, can lower qi, promote diuresis, moistening lung, smoothing intestines, clearing away heat and toxic materials, cooling blood, stopping bleeding, strengthening the spleen and stomach, moistening lung, smoothing intestines, clearing away the heart-fire, tranquilizing the middle-jiao, replenishing qi, moistening the lung, relieving cough, eliminating various inflammations in internal organs and six entrails, and enhancing the function of an anti-pain system, and, Eliminating edema, reducing rheumatic arthralgia, damp-heat limb pain, diminishing inflammation, resisting bacteria, repairing diseases of stomach, spleen, stomach, intestine, lung, liver and kidney by using combination of lily, bunge cherry seed, erythrina bark, rhizoma corydalis processed with vinegar, achyranthes root, chinaroot greenbrier and myrrh processed with vinegar, strengthening body function, reducing invasion of external environment to body, furthermore, the combination of lily, rhizoma corydalis processed with vinegar, kadsura pepper stem, achyranthes and cyathula root and chinaroot greenbrier is utilized to expand blood vessels, reduce blood symptoms, promote the heart rhythm to be normal and correct the cardio-cerebral diseases.

Claims (2)

1. A Chinese herbal medicine product for treating calendar festival wind, gout and condyle pain is characterized in that: the Chinese herbal medicines comprise lily, bunge cherry seed, rhizoma corydalis processed with vinegar, radix stephaniae tetrandrae, erythrina bark, garden balsam stem, futokadsura stem, chinaroot greenbrier rhizome, achyranthes root and myrrh processed with vinegar, and the auxiliary materials are dextrin, wherein the weight parts of the Chinese herbal medicines are dextrin, lily, bunge cherry seed, rhizoma corydalis processed with vinegar, radix stephaniae tetrandrae, erythrina bark, garden balsam stem, futokadsura stem, chinaroot greenbrier rhizome, achyranthes root and myrrh processed with vinegar are = 100: 15-25: 20-30: 15-20: 20-30: 15-30.

2. The herbal product of claim 1, wherein the herbal product is for the treatment of almanac, gout, and condyloma pain: the preparation method of the Chinese herbal medicine product comprises the following steps:

1) according to the weight of the medicine, the lily, the bunge cherry seed, the vinegar rhizoma corydalis, the radix stephaniae tetrandrae, the erythrina bark, the impatiens balsamina, the futokadsura stem, the smilax, the achyranthes, the vinegar myrrh = 100: 15-25: 20-30: 15-20: 20-30: 15-25: 20-30: 15-30 are respectively screened and weighed according to the weight part ratio of the dextrin, the lily, the bunge cherry seed, the vinegar rhizoma corydalis, the radix stephaniae tetrandrae, the erythrina bark, the impatiens balsamina, the futokadsura stem, the smilax, the achyranthes, the vinegar myrrh and the dextrin;

2) mixing the weighed medicinal materials, putting the mixture into an extraction pot, adding water which is 5-12 times of the total weight of the medicinal materials into the medicinal materials, soaking for 60 minutes, extracting by using ultrasonic waves at the temperature of 100 ℃, extracting twice by using the ultrasonic waves, and heating for 100 minutes each time;

3) filtering the medicinal liquid with a pipeline centrifuge to remove residue, mixing the two extractive solutions, and mixing;

4) vacuum concentrating the mixed extractive solution at low temperature with double-effect vacuum concentrator to obtain soft extract;

5) cooling the concentrated soft extract with a freeze dryer at-40 deg.C, and freezing to obtain dry extract;

6) crushing the dry paste into 80-mesh fine powder, filling the fine powder into bags, packing the bags in a sealing mode, or pressing the dry paste powder into tablets and packing the tablets in a sealing mode, or pressing the dry paste powder into 100-300 times of water, preparing oral liquid and syrup, filling and sterilizing.