CN114585722A - 图像解析装置、细胞培养观察装置、图像解析方法、程序及信息处理系统 - Google Patents

图像解析装置、细胞培养观察装置、图像解析方法、程序及信息处理系统 Download PDF

Info

Publication number
CN114585722A
CN114585722A CN202080071863.1A CN202080071863A CN114585722A CN 114585722 A CN114585722 A CN 114585722A CN 202080071863 A CN202080071863 A CN 202080071863A CN 114585722 A CN114585722 A CN 114585722A
Authority
CN
China
Prior art keywords
area
region
image
unit
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080071863.1A
Other languages
English (en)
Chinese (zh)
Inventor
市桥彻
山嵜洋一
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nikon Corp
Original Assignee
Nikon Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nikon Corp filed Critical Nikon Corp
Publication of CN114585722A publication Critical patent/CN114585722A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G06T7/0014—Biomedical image inspection using an image reference approach
    • G06T7/0016—Biomedical image inspection using an image reference approach involving temporal comparison
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/34—Measuring or testing with condition measuring or sensing means, e.g. colony counters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/4833—Physical analysis of biological material of solid biological material, e.g. tissue samples, cell cultures
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T5/00—Image enhancement or restoration
    • G06T5/70—Denoising; Smoothing
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/60—Analysis of geometric attributes
    • G06T7/62—Analysis of geometric attributes of area, perimeter, diameter or volume
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Quality & Reliability (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Geometry (AREA)
  • Sustainable Development (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN202080071863.1A 2019-09-04 2020-09-04 图像解析装置、细胞培养观察装置、图像解析方法、程序及信息处理系统 Pending CN114585722A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2019-161011 2019-09-04
JP2019161011A JP7532754B2 (ja) 2019-09-04 2019-09-04 画像解析装置、細胞培養観察装置、画像解析方法、及びプログラム
PCT/JP2020/033666 WO2021045214A1 (ja) 2019-09-04 2020-09-04 画像解析装置、細胞培養観察装置、画像解析方法、プログラム、及び情報処理システム

Publications (1)

Publication Number Publication Date
CN114585722A true CN114585722A (zh) 2022-06-03

Family

ID=74846839

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080071863.1A Pending CN114585722A (zh) 2019-09-04 2020-09-04 图像解析装置、细胞培养观察装置、图像解析方法、程序及信息处理系统

Country Status (5)

Country Link
US (1) US12315162B2 (https=)
EP (1) EP4026891A4 (https=)
JP (1) JP7532754B2 (https=)
CN (1) CN114585722A (https=)
WO (1) WO2021045214A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113373198A (zh) * 2021-06-17 2021-09-10 上海睿钰生物科技有限公司 一种确定细胞的迁移能力的方法和系统

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009229276A (ja) * 2008-03-24 2009-10-08 Nikon Corp 細胞観察の画像解析方法、画像処理プログラム及び画像処理装置
US20130051651A1 (en) * 2010-05-07 2013-02-28 Purdue Research Foundation Quantitative image analysis for wound healing assay
CN104641229A (zh) * 2012-07-20 2015-05-20 新加坡科技研究局 预测肾近曲小管细胞毒性的体外试验
JP2016182142A (ja) * 2016-07-05 2016-10-20 株式会社ニコン 画像処理装置および方法、並びにプログラム

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120028288A1 (en) 2005-12-07 2012-02-02 Nao Nitta Method for Measuring Cell Motility and System Therefor
JP4953092B2 (ja) 2008-03-04 2012-06-13 株式会社ニコン 細胞観察における生細胞の判別手法、細胞観察の画像処理プログラム及び画像処理装置
WO2009119330A1 (ja) 2008-03-24 2009-10-01 株式会社ニコン 細胞観察の画像解析方法、画像処理プログラム及び画像処理装置
US8515143B2 (en) 2009-01-09 2013-08-20 Dai Nippon Printing Co., Ltd. Embryo quality evaluation assistance system, embryo quality evaluation assistance apparatus and embryo quality evaluation assistance method
JP5740101B2 (ja) 2010-04-23 2015-06-24 国立大学法人名古屋大学 細胞評価装置、インキュベータ、細胞評価方法、細胞評価プログラムおよび細胞の培養方法
JP5816416B2 (ja) 2010-04-23 2015-11-18 国立大学法人名古屋大学 細胞評価装置、インキュベータ、プログラム、および、培養方法
JP5821444B2 (ja) 2011-09-09 2015-11-24 大日本印刷株式会社 細胞画像解析装置、細胞画像解析方法、及び細胞画像解析プログラム
AU2013266235B2 (en) * 2012-05-25 2017-06-08 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of regulating cannabinoid receptor activity-related disorders and diseases
JP6102166B2 (ja) 2012-10-10 2017-03-29 株式会社ニコン 心筋細胞の運動検出方法、心筋細胞の培養方法、薬剤評価方法、画像処理プログラム及び画像処理装置
JP6128677B2 (ja) 2013-02-05 2017-05-17 公立大学法人大阪市立大学 神経細胞の遊走障害を伴う疾患の判定方法及びその利用
JP6494903B2 (ja) 2013-02-14 2019-04-03 ソニー株式会社 分析システム、分析プログラム及び分析方法
JP6097951B2 (ja) * 2013-08-22 2017-03-22 富士フイルム株式会社 幹細胞分化判定装置および方法並びにプログラム
JP6468895B2 (ja) * 2015-03-11 2019-02-13 日本メナード化粧品株式会社 幹細胞の未分化状態維持剤及び増殖促進剤
US10907212B2 (en) 2016-05-14 2021-02-02 Regents Of The University Of Minnesota Inhibitors of cell adhesion
JP2018014991A (ja) 2016-07-13 2018-02-01 ソニー株式会社 情報処理装置、情報処理方法及び情報処理システム
JP6864313B2 (ja) 2016-12-20 2021-04-28 株式会社Ｓｃｒｅｅｎホールディングス 化学物質の評価方法
JP6424911B2 (ja) 2017-02-28 2018-11-21 株式会社ニコン 心筋細胞の運動検出方法、心筋細胞の培養方法、薬剤評価方法、画像処理プログラム及び画像処理装置
JP7011770B2 (ja) * 2017-06-26 2022-01-27 大日本印刷株式会社 細胞培養状態評価装置
JP6939170B2 (ja) 2017-07-19 2021-09-22 大日本印刷株式会社 画像表示装置、プログラム及び制御方法
JP6795004B2 (ja) 2018-03-13 2020-12-02 株式会社村田製作所 巻線型コイル部品
EP3964562B1 (en) * 2019-04-26 2025-11-05 Nikon Corporation Cell tracking method, image processing device, and program
EP4177332A4 (en) * 2020-07-02 2025-04-30 FUJIFILM Corporation INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD AND PROGRAM

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009229276A (ja) * 2008-03-24 2009-10-08 Nikon Corp 細胞観察の画像解析方法、画像処理プログラム及び画像処理装置
US20130051651A1 (en) * 2010-05-07 2013-02-28 Purdue Research Foundation Quantitative image analysis for wound healing assay
CN104641229A (zh) * 2012-07-20 2015-05-20 新加坡科技研究局 预测肾近曲小管细胞毒性的体外试验
JP2016182142A (ja) * 2016-07-05 2016-10-20 株式会社ニコン 画像処理装置および方法、並びにプログラム

Also Published As

Publication number Publication date
JP2021036830A (ja) 2021-03-11
US20220327694A1 (en) 2022-10-13
JP7532754B2 (ja) 2024-08-14
EP4026891A1 (en) 2022-07-13
EP4026891A4 (en) 2023-10-11
US12315162B2 (en) 2025-05-27
WO2021045214A1 (ja) 2021-03-11

Similar Documents

Publication Publication Date Title
US10416433B2 (en) Cell image acquisition device, method, and program
EP3065105B1 (en) Technique for determining the state of a cell aggregation, image processing program and image processing device using the technique, and method for producing a cell aggregation
JP5446868B2 (ja) プログラム、コンピュータおよび培養状態解析方法
JPWO2006051813A1 (ja) 細胞培養装置、画像処理装置及び細胞検出システム
JP6015113B2 (ja) 細胞評価装置、細胞評価方法およびプログラム
JP6015112B2 (ja) 細胞評価装置、細胞評価方法およびプログラム
JPWO2009031283A1 (ja) 培養装置、培養情報管理方法およびプログラム
US9145572B2 (en) Observation system, recording medium, and control method of observation system
CN102471744A (zh) 图像处理装置、培养观察装置及图像处理方法
CN114127307B (zh) 细胞图像解析方法和细胞图像解析装置
JPWO2010146802A1 (ja) 細胞塊の状態判別方法、この方法を用いた画像処理プログラム及び画像処理装置、並びに細胞塊の製造方法
US10538729B2 (en) Cell imaging control device, method, and program
WO2015025506A1 (ja) 幹細胞分化判定装置および方法並びにプログラム
JP6130801B2 (ja) 細胞領域表示制御装置および方法並びにプログラム
WO2015133193A1 (ja) 細胞画像評価装置および方法並びにプログラム
JP2011004638A (ja) 受精卵観察の画像処理方法、画像処理プログラム及び画像処理装置
CN114585722A (zh) 图像解析装置、细胞培养观察装置、图像解析方法、程序及信息处理系统
JP2012039929A (ja) 受精卵観察の画像処理方法、画像処理プログラム及び画像処理装置、並びに受精卵の製造方法
JP2006209698A (ja) 対象追跡装置、顕微鏡システムおよび対象追跡プログラム
JP6343874B2 (ja) 観察装置、観察方法、観察システム、そのプログラム、および細胞の製造方法
JP2013113818A (ja) 画像処理装置、顕微鏡システム、画像処理方法、及び画像処理プログラム
EP4071471A1 (en) Taxis analysis method, cancer evaluation method, taxis analysis system, and program
US20250139787A1 (en) Image processing device, image processing method, and storage medium
JP2017000163A (ja) 細胞評価装置、細胞評価方法およびプログラム
JP6447601B2 (ja) 細胞評価装置、細胞評価方法およびプログラム

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination