CN114486466A - Method and equipment for realizing automatic embedding - Google Patents

Method and equipment for realizing automatic embedding Download PDF

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Publication number
CN114486466A
CN114486466A CN202111655910.XA CN202111655910A CN114486466A CN 114486466 A CN114486466 A CN 114486466A CN 202111655910 A CN202111655910 A CN 202111655910A CN 114486466 A CN114486466 A CN 114486466A
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embedding
piece
box
embedding box
wax
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CN202111655910.XA
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CN114486466B (en
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代建东
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Shandong Junteng Medical Technology Co ltd
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Shandong Junteng Medical Technology Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/36Embedding or analogous mounting of samples

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Pathology (AREA)
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Abstract

The application relates to the technical field of pathological tissue treatment, in particular to a method and equipment for realizing automatic embedding, wherein the method for realizing automatic embedding comprises the following steps: step 1, a plurality of embedding boxes are positioned in a containing area and are stacked in sequence in the vertical direction; step 2, the input mechanism vertically separates the bottommost embedding box from other embedding boxes, moves the bottommost embedding box out of the containing area, and then moves the other embedding boxes downwards to the bottom of the containing area; step 3, placing the embedding box separated from the accommodating area on a movable bearing mechanism, and enabling the bearing mechanism to drive the embedding box to move along a set path; and 4, arranging a heating area, a wax dropping area and a cooling area on the set path. The equipment for realizing automatic embedding comprises a storage basket, an input mechanism, a bearing mechanism and an embedding mechanism. This application can simplify the operating procedure, reduces intensity of labour, improves embedding efficiency.

Description

Method and equipment for realizing automatic embedding
Technical Field
The application relates to the technical field of pathological tissue treatment, in particular to a method and equipment for realizing automatic embedding.
Background
With the development of precise medicine, the pathological diagnosis function is increasingly prominent, and the manufacture of pathological sections is an important link of pathological diagnosis. The preparation of pathological section usually includes the steps of material taking, fixing, dehydration, wax dipping, embedding, slicing, staining and the like. In the traditional pathological section manufacturing process, an embedding box is needed, and comprises a box cover and a box body. Medical personnel place the tissue in the embedding box to cover the lid, dehydrating, after the wax-dipping is handled, medical personnel take out the tissue from the embedding box, place the tissue in the forming die who has the paraffin of notes, then place the box body of embedding box on forming die, and get rid of the lid, pour into paraffin into to box body inside again, after the freeze-forming, need medical personnel with box body and forming die separation. The embedding process is complicated, the labor intensity is high, and the embedding efficiency is low.
Disclosure of Invention
In order to solve the technical problems, the application provides a method and equipment for realizing automatic embedding, which can simplify the operation steps, reduce the labor intensity, improve the embedding efficiency and effectively solve the problems in the prior art.
In order to solve the problems, the application provides a method for realizing automatic embedding, and provides an embedding box, wherein the bottom of the embedding box protrudes downwards to form a containing cavity for containing tissues, the upper edge of the embedding box extends upwards to form a wax dropping cavity, and the top wall of the containing cavity is provided with a wax inlet hole communicated with the wax dropping cavity; providing an input mechanism; the method for realizing automatic embedding comprises the following steps:
step 1, a plurality of embedding boxes are positioned in a containing area and are sequentially stacked in the vertical direction, and in two adjacent embedding boxes, the convex bottom of one embedding box is inserted into a wax dropping cavity of the other embedding box;
step 2, the input mechanism vertically separates the bottommost embedding box from other embedding boxes, moves the bottommost embedding box out of the containing area, and then moves the other embedding boxes downwards to the bottom of the containing area;
step 3, placing the embedding box separated from the accommodating area on a movable bearing mechanism, and enabling the bearing mechanism to drive the embedding box to move along a set path;
step 4, a heating area, a wax dripping area and a cooling area are arranged on the set path, and wax is heated and melted when the embedding box moves to the heating area; dripping wax into the embedding box when the embedding box moves to a wax dripping area; and when the embedding box moves to the cooling area, the wax block of the embedding box is cooled and formed.
Further, the input mechanism comprises a floating piece and an input piece, and the step 2 comprises the following steps:
2.1, connecting the floating piece with a penultimate embedding box in the containing area;
and 2.2, the input piece moves towards the bottommost embedding box, meanwhile, the input piece jacks up the floating piece, the floating piece drives the penultimate embedding box and the embedding box above the penultimate embedding box to move upwards, so that the bottommost embedding box is separated from other embedding boxes, and the input piece pushes the bottommost embedding box out of the storage area.
The application still provides an equipment of automatic embedding of realization, and its characterized in that is suitable for and carries out the embedding processing to the embedding box, and the bottom of embedding box is the chamber that holds of protrusion in order to form the holding tissue downwards, and the top edge of embedding box upwards extends in order to enclose and drips the wax chamber, and the roof that holds the chamber is equipped with and drips the wax hole that advances that the wax chamber communicates, and the equipment that realizes automatic embedding includes:
the storage basket forms a storage cavity for storing the embedding box, the storage cavity extends in the vertical direction, one side wall of the storage basket is provided with an outlet through which the embedding box leaves the storage cavity, the other side wall of the storage basket corresponding to the outlet is provided with an inlet communicated with the storage cavity, the side wall of the storage basket is provided with a sliding groove extending in the vertical direction, and the sliding groove is communicated with the storage cavity;
the input mechanism comprises an input piece and a floating piece, the input piece is positioned on the side of the inlet, and the input piece moves between an initial position and an input position along a set direction so that the end part of the input piece moves between the inlet and the outlet; one end of the floating piece is positioned on the side of the sliding groove to be connected with the penultimate embedding box, when the input piece is positioned at the initial position, at least part of the input piece is positioned on the side of one end, far away from the containing basket, of the floating piece, and when the input piece is positioned at the input position, the part, positioned on the side of the floating piece, of the input piece moves to the lower side of the floating piece, so that the floating piece moves upwards;
the bearing mechanism comprises a bearing piece for bearing the embedding box and a driving piece for driving the bearing piece to move along a set path;
embedding mechanism, embedding mechanism include along the heating member that sets for the route setting, drip wax spare, cooling part, drip wax spare and locate between heating member and the cooling part.
Furthermore, the wall of the wax dropping cavity of the embedding box forms a connecting wall, the connecting wall is provided with a connecting hole, the floating part comprises a floating block and a fixing clamping jaw connected to the floating block, and the inner side of the fixing clamping jaw forms a fixing column which is inserted into the connecting hole.
Furthermore, a first inclined plane is formed on one side, far away from the containing basket, of the floating block, and the first inclined plane faces downwards and extends towards the direction close to the containing basket in an inclined mode; the input piece comprises a box pushing part positioned below the floating block, one end, far away from the containing basket, of the box pushing part is upwards protruded to form an upper top part, one side, close to the containing basket, of the upper top part forms a second inclined plane, and the second inclined plane faces downwards and extends towards the direction close to the containing basket in an inclined mode; when the input piece is located at the initial position, the upper top part is located on the side of the first inclined plane.
Furthermore, a fixing piece is arranged above the floating piece, and the floating piece is connected to the fixing piece through an elastic piece, so that the floating piece can vertically move relative to the fixing piece.
Further, realize equipment of automatic embedding still includes brace table and fixture, and the side of export is located in order to bear the weight of the embedding box who shifts out the storage chamber to the brace table, and fixture is equipped with the spliced pole of plug-in fit in the connecting hole including connecting clamping jaw and power piece, the inboard of connecting the clamping jaw, and power piece can drive and connect the clamping jaw and move between brace table and carrier.
Further, fixture still includes the lifter, and the lifter is connected in the top of connecting the clamping jaw to make connecting the clamping jaw move in vertical.
Furthermore, the equipment for realizing automatic embedding also comprises a box pressing part which can vertically move along the sliding groove.
Further, the diapire of embedding box is equipped with the flowing liquid hole, and it includes fixed part and fixed buckle to hold carrier, and the fixed part forms and supplies embedding box male fixed slot, and the diapire of fixed slot is equipped with the sealed arch that inserts the flowing liquid hole, and fixed buckle articulates in the fixed part and can lock in the embedding box.
The beneficial effects of this application lie in, the tissue after dehydration, the wax-dipping are handled is placed in the storage area along with the embedding box, when placing a plurality of embedding boxes, and the bottom of an embedding box inserts in another embedding box in order to pile up in proper order vertically, can save the space that the embedding box took vertically, and limit each other between two adjacent embedding boxes moreover, it is more stable under the state of piling up. The input mechanism can separate the bottommost embedding box from other embedding boxes stacked above the bottommost embedding box, and move the bottommost embedding box out of the containing area, and the embedding box moved out of the containing area is placed on the bearing mechanism to move along a set path. Compare in traditional embedding method, the method of the automatic embedding of realization that this application provided can make the tissue shaping in the embedding box, need not take out the tissue in the embedding box and place in independent forming die, also need not get rid of the operation of lid, can simplify the operating procedure, improves embedding efficiency. Moreover, the bearing mechanism drives the embedding box to move to complete the steps of heating, wax dripping, cooling and separating, so that labor can be saved, and the labor intensity is reduced. The method and the equipment for realizing automatic embedding effectively solve the problems in the prior art.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:
fig. 1 is a schematic front view of an apparatus for implementing automatic embedding according to an embodiment of the present disclosure.
Fig. 2 is a schematic top view of an apparatus for implementing automatic embedding according to an embodiment of the present disclosure.
Fig. 3 is a front view of an embedding cassette according to an embodiment of the present disclosure.
Fig. 4 is a schematic perspective view of an embedding cassette according to an embodiment of the present application.
Fig. 5 is a schematic cross-sectional structure diagram of an embedding cassette in an embodiment of the present application.
Fig. 6 is a schematic perspective view of a storage basket according to an embodiment of the present application.
Fig. 7 is a front view of a storage basket according to an embodiment of the present application.
Fig. 8 is a schematic structural diagram of an input mechanism according to an embodiment of the present application.
FIG. 9 is a schematic structural diagram of the floating member and the fixing member in an embodiment of the present application.
Fig. 10 is a schematic structural diagram of an input element according to an embodiment of the present application.
Fig. 11 is a partial structural schematic view of a clamping mechanism according to an embodiment of the present application.
Fig. 12 is a schematic structural view of an embedding cassette placed on a carrier according to an embodiment of the present application.
Fig. 13 is a schematic structural diagram of a carrier in an embodiment of the present application.
Wherein: 1. embedding boxes; 101. an accommodating chamber; 102. a wax inlet hole; 103. a connecting wall; 1031. connecting holes; 104. a liquid flow hole; 2. a storage basket; 201. a receiving cavity; 202. an outlet; 203. an inlet; 204. a chute; 3. an input member; 301. a box pushing part; 302. an upper top; 3021. a second inclined plane; 4. a float member; 401. a slider; 4011. a first inclined plane; 402. fixing the clamping jaw; 4021. fixing a column; 5. a carrier; 501. a fixed part; 5011. fixing grooves; 5012. sealing the protrusion; 502. fixing the buckle; 6. a drive member; 7. a heating member; 8. a wax dropping part; 9. a cooling member; 10. a fixing member; 11. a support table; 12. connecting the clamping jaws; 121. connecting columns; 13. a power member; 14. a lifting member; 15. pressing the box piece; 16. an elastic member.
Detailed Description
In order to more clearly explain the overall concept of the present application, the following detailed description is given by way of example in conjunction with the accompanying drawings.
It should be noted that in the following description, numerous specific details are set forth in order to provide a thorough understanding of the present application, however, the present application may be practiced otherwise than as specifically described herein and, therefore, the scope of the present application should not be limited by the specific embodiments disclosed below.
In addition, in the description of the present application, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", "circumferential", and the like, indicate orientations and positional relationships based on those shown in the drawings, are only for convenience of description and simplicity of description, and do not indicate or imply that the referenced devices or elements must have a particular orientation, be constructed and operated in a particular orientation, and thus, are not to be construed as limiting the present application.
In this application, unless expressly stated or limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can include, for example, fixed connections, removable connections, or integral parts; either directly or indirectly through intervening media, either internally or in any other relationship. However, the direct connection means that the two bodies are not connected to each other by the intermediate structure but connected to each other by the connecting structure to form a whole. The specific meaning of the above terms in the present application can be understood by those of ordinary skill in the art as appropriate.
In this application, unless expressly stated or limited otherwise, a first feature is "on" or "under" a second feature such that the first and second features are in direct contact, or the first and second features are in indirect contact via an intermediary. In the description herein, reference to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the application. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The application provides a method for realizing automatic embedding, and provides an embedding box 1, wherein the bottom of the embedding box 1 protrudes downwards to form a containing cavity 101 for containing tissues, the bottom of the embedding box 1 protrudes downwards to form the containing cavity 101 for containing tissues, the upper edge of the embedding box 1 extends upwards to form a wax dropping cavity, the top wall of the containing cavity 101 is provided with a wax inlet hole 102 communicated with the wax dropping cavity, and an input mechanism is also provided; the method for realizing automatic embedding comprises the following steps:
step 1, a plurality of embedding boxes 1 are positioned in a containing area and are sequentially stacked in the vertical direction, and in two adjacent embedding boxes 1, the convex bottom of one embedding box 1 is inserted into a wax dropping cavity of the other embedding box 1;
step 2, the input mechanism vertically separates the bottommost embedding box 1 from other embedding boxes 1, the input mechanism moves the bottommost embedding box 1 out of the containing area, and then the other embedding boxes 1 downwards move to the bottom of the containing area;
step 3, placing the embedding box 1 separated from the accommodating area on a movable bearing mechanism, and enabling the bearing mechanism to drive the embedding box 1 to move along a set path;
step 4, a heating area, a wax dripping area and a cooling area are arranged on the set path, and wax is heated and melted when the embedding box 1 moves to the heating area; dripping wax into the embedding box 1 when the embedding box 1 moves to a wax dripping area; when the embedding box 1 moves to the cooling area, the wax block of the embedding box 1 is cooled and formed.
The application provides a method for realizing automatic embedding, tissue after dehydration, wax immersion processing is placed in the storage area along with embedding box 1, when placing a plurality of embedding boxes 1, the convex bottom of one embedding box 1 is inserted into the wax dropping cavity of another embedding box 1 and is stacked in order vertically in proper order, can save the space that embedding box 1 vertically occupied, and limit each other between two adjacent embedding boxes 1 moreover, it is more stable under the state of piling up. The input mechanism can separate the bottommost embedding cassette 1 from the other embedding cassettes 1 stacked above it and move the bottommost embedding cassette 1 out of the storage area, and the embedding cassette 1 moved out of the storage area is placed on the carrying mechanism to move along a set path.
Some solidified paraffin remains on the cassette 1 after the tissue is waxed. After the heating process is performed in the heating area, the solidified paraffin on the embedding box 1 is melted, and the solidified paraffin can be prevented from blocking the paraffin inlet hole 102 on the embedding box 1. After the embedding box 1 moves to the wax dropping area, the paraffin liquid can flow into the accommodating cavity 101 through the wax inlet hole 102. The cassette 1 is moved to a cooling zone where paraffin can be solidified and shaped, and the paraffin combines with the tissue to form a tissue wax block. The tissue wax block can be removed from the receiving cavity 101 of the cassette 1 for subsequent processing.
Compared with the traditional embedding method, the method for realizing automatic embedding provided by the application can enable the tissue to be molded in the embedding box 1, the tissue in the embedding box 1 does not need to be taken out and placed in an independent molding die, the operation of removing the box cover is also not needed, the operation steps can be simplified, and the embedding efficiency is improved. Moreover, the bearing mechanism drives the embedding box 1 to move to complete the steps of heating, wax dripping, cooling and separating, so that the labor can be saved, and the labor intensity can be reduced.
In a preferred embodiment, and more particularly, the input mechanism comprises a float member 4 and an input member 3, and step 2 comprises:
step 2.1, connecting the floating piece 4 with the penultimate embedding box 1 in the containing area;
and 2.2, the input piece 3 moves towards the bottommost embedding box 1, meanwhile, the input piece 3 jacks up the floating piece 4 upwards, the floating piece 4 drives the penultimate embedding box 1 and the embedding box 1 above the penultimate embedding box 1 to move upwards so as to separate the bottommost embedding box 1 from other embedding boxes 1, and the input piece 3 pushes the bottommost embedding box 1 out of the containing area.
In the present embodiment, the bottommost embedding cassette 1 does not need to be moved in the vertical direction, and the carrying mechanism only moves the other embedding cassettes 1 upward, so that the bottommost embedding cassette 1 is separated from the other embedding cassettes 1. Further, the input member 3 can lift up the floating member 4 while moving toward the bottommost embedding cassette 1, that is, the step of separating the bottommost embedding cassette 1 from other embedding cassettes 1 and the step of pushing out the bottommost embedding cassette 1 from the storage area are performed simultaneously, and time can be saved.
In the present application, the bottommost cassette 1 refers to one cassette 1 located at the bottom of the storage area, the other cassettes 1 refer to the other cassettes 1 located above the bottommost cassette 1, and the penultimate cassette 1 refers to the second cassette 1 counting upward from the bottom.
The application still provides an equipment of realizing automatic embedding, as shown in fig. 1 to fig. 13, be suitable for and carry out the embedding processing to embedding box 1, the bottom of embedding box 1 is the chamber 101 that holds that projects downwards in order to form the holding tissue, the top edge of embedding box 1 upwards extends in order to enclose into dripping the wax chamber, the roof that holds chamber 101 is equipped with and drips wax chamber intercommunication advance wax hole 102, the equipment of realizing automatic embedding is including accomodating basket 2, input mechanism, bearing mechanism, embedding mechanism. The containing basket 2 forms a containing cavity 201 for containing the embedding box 1, the containing cavity 201 extends in the vertical direction, one side wall of the containing basket 2 is provided with an outlet 202 for the embedding box 1 to leave the containing cavity 201, the other side wall of the containing basket 2 corresponding to the outlet 202 is provided with an inlet 203 communicated with the containing cavity 201, the side wall of the containing basket 2 is provided with a sliding groove 204 extending in the vertical direction, and the sliding groove 204 is communicated with the containing cavity 201; the input mechanism comprises an input member 3 and a floating member 4, the input member 3 is positioned at the side of the inlet 203, the input member 3 moves between an initial position and an input position along a set direction, so that the end part of the input member 3 moves between the inlet 203 and the outlet 202; one end of the floating piece 4 is positioned at the side of the sliding groove 204 to be connected with the penultimate embedding box 1, when the input piece 3 is positioned at the initial position, at least part of the input piece 3 is positioned at the side of one end of the floating piece 4 far away from the containing basket 2, and when the input piece 3 is positioned at the input position, the part of the input piece 3 positioned at the side of the floating piece 4 moves to the lower part of the floating piece 4, so that the floating piece 4 moves upwards; the bearing mechanism comprises a bearing piece 5 for bearing the embedding box 1 and a driving piece 6 for driving the bearing piece 5 to move along a set path; the embedding mechanism comprises a heating part 7, a wax dripping part 8 and a cooling part 9 which are arranged along a set path, wherein the wax dripping part 8 is arranged between the heating part 7 and the cooling part 9.
The utility model provides an equipment of automatic embedding of realization, it accomodates basket 2 and can accomodate a plurality of embedding boxes 1, and the convex bottom of an embedding box 1 can insert another embedding box 1's the wax intracavity of dripping in order to pile up in proper order vertically, can save the space that embedding box 1 vertically took, and limit each other between two adjacent embedding boxes 1 moreover, and is more stable under the state of piling up. When the input piece 3 is at the initial position, the floating piece 4 can be connected with the penultimate embedding box 1 through the sliding groove 204, in the process that the input piece 3 moves towards the inlet 203, the part of the input piece 3, which is positioned on the side of the floating piece 4, moves to the lower side of the floating piece 4 to jack up the floating piece 4 upwards, and the floating piece 4 drives other embedding boxes 1 above the bottommost embedding box 1 to move upwards, so that the bottommost embedding box 1 is separated from other embedding boxes 1. The input member 3 continues to move toward the inlet 203 to push the bottommost cassette 1 out of the receiving chamber 201 from the outlet 202. After the input member 3 returns to the initial position, the floating member 4 moves downward to drive other embedding boxes 1 to move downward, and when the floating member 4 returns to the original position, the floating member 4 can be separated from the embedding box 1, so that the embedding box 1 continues to move downward to the bottom of the storage basket 2. Of course, after the input member 3 is separated from the storage chamber 201, the floating member may be separated from the cassette 1, and the cassette 1 may be moved downward by its own weight or other acting force.
The embedding cassette 1 leaving the containing chamber 201 can be placed on the carrier 5, and the carrier 5 drives the embedding cassette 1 to move on the set path. Some solidified paraffin remains on the cassette 1 after the tissue is waxed. After the heating member 7 heats the embedding box 1, the solidified paraffin on the embedding box 1 is melted, and the solidified paraffin can be prevented from blocking the paraffin inlet 102 on the embedding box 1. Then the embedding box 1 moves to the position of the wax dropping piece 8, and the paraffin liquid flows into the accommodating cavity 101 from the wax inlet hole 102 of the embedding box 1. After the wax is dropped, the cooling element 9 is able to solidify the paraffin wax to form a tissue wax mass in combination with the tissue.
Compared with the traditional embedding method, the method for realizing automatic embedding provided by the application can enable the tissue to be molded in the embedding box 1, the tissue in the embedding box 1 does not need to be taken out and placed in an independent molding die, the operation of removing the box cover is also not needed, the operation steps can be simplified, and the embedding efficiency is improved. Moreover, the bearing mechanism drives the embedding box 1 to move to complete the steps of heating, wax dripping, cooling and separating, so that the labor can be saved, and the labor intensity can be reduced.
It should be noted that the form of the heating element 7, the wax dropping element 8 and the cooling element 9 is not limited in the present application, for example, the heating element 7 may be in the form of hot air blowing, electrothermal baking, infrared, etc.; the cooling part 9 can adopt a refrigeration system consisting of a refrigeration compressor, a condenser, a throttling device and an evaporator; the wax dropping member 8 may have a wax dropping square structure as in the prior art. In addition, the form of the driving member 6 is not limited in the present application, and for example, the driving member 63 may be a motor. The present application does not limit the conveyance form of the carrier 5, and for example, a conveyor chain conveyance, a flat belt conveyance, a timing belt conveyance, or the like may be used.
Regarding the form of the floating member 4, in a preferred embodiment, further specifically, the wall of the wax dropping chamber of the embedding cassette 1 forms a connecting wall 103, the connecting wall 103 is provided with a connecting hole 1031, the floating member 4 includes a floating block 401 and a fixing jaw 402 connected to the floating block 401, and the inner side of the fixing jaw 402 forms a fixing post 4021 insertion-fitted to the connecting hole 1031. As shown in fig. 6 and 9, the fixing column 4021 can extend into the receiving cavity 201 from the sliding groove 204 to be inserted into the connecting hole 1031 of the embedding box 1, and the fixing column 4021 can move along the sliding groove. The fixing column 4021 facilitates the clamping of the cassette 1 by the fixing jaw 402, and can improve the reliability of the clamping and prevent the cassette 1 from being separated from the fixing jaw 402 in the upward movement process.
In the preferred embodiment, more specifically, a side of the slider 401 away from the receiving basket 2 is formed with a first inclined surface 4011, and the first inclined surface 4011 extends downward and slantingly toward the receiving basket 2; the input member 3 comprises a box pushing part 301 positioned below the floating block 401, one end of the box pushing part 301 far away from the receiving basket 2 is upwards protruded to form an upper top part 302, one side of the upper top part 302 close to the receiving basket 2 is provided with a second inclined surface 3021, and the second inclined surface 3021 is downwards and obliquely extends towards the direction close to the receiving basket 2; when the input member 3 is located at the initial position, the upper top portion 302 is located on the side of the first inclined surface 4011. During movement of input member 3 toward inlet 203, second sloped surface 3021 of upper top portion 302 moves along first sloped surface 4011 of slider 401 to below slider 401 to cause slider 401 to move upward. First ramp 4011 and second ramp 3021 are capable of guiding upper crown 302 to lift slider 401 without being prone to jamming.
In the preferred embodiment, further specifically, a fixing member 10 is provided above the floating member 4, and the floating member 4 is connected to the fixing member 10 through an elastic member 16 so that the floating member 4 can move vertically relative to the fixing member 10. As shown in fig. 8, the fixing member 10 can be fixed on the frame, and the elastic member 16 is compressed after the floating member 4 is jacked up by the input member 3; when the input member 3 is restored to the initial position, the floating member 4 can automatically return to the original position under the elastic force of the elastic member 16.
It should be noted that the form of the elastic member 16 is not limited in this embodiment, and for example, the elastic member 16 may be a spring.
In a preferred embodiment, more specifically, the apparatus for realizing automatic embedding further comprises a supporting platform 11 and a clamping mechanism, the supporting platform 11 is disposed at the side of the outlet 202 to bear the embedding box 1 moving out of the containing cavity 201, the clamping mechanism comprises a connecting clamping jaw 12 and a power piece 13, the inner side of the connecting clamping jaw 12 is provided with a connecting column 121 inserted and matched with the connecting hole 1031, and the power piece 13 can drive the connecting clamping jaw 12 to move between the supporting platform 11 and the bearing piece 5. As shown in fig. 1, the cassette 1 leaving the storage chamber 201 can be temporarily stored on the support table 11, and as shown in fig. 11, the connecting column 121 of the connecting jaw 12 can be insert-fitted into the connecting hole 1031 to bring the cassette 1 at the support table 11 to the carrier 5. When the connecting jaw 12 is moved to the carrier 5, the cassette 1 can be released, so that the cassette 1 is placed on the carrier 5. The connecting column 121 on the inner side of the connecting clamping jaw 12 can improve the reliability of clamping the embedding box 1 by the connecting clamping jaw 12 and prevent the embedding box 1 from being separated from the connecting clamping jaw 12.
It should be noted that the form of the power member 13 is not limited in this embodiment, for example, the power member 13 includes a motor, two synchronous pulleys, a synchronous belt, and four parallel connecting rods, the two synchronous pulleys are connected by the synchronous belt, one of the synchronous pulleys is connected to the motor, the other synchronous pulley is connected to the four parallel connecting rods, and the connecting clamping jaw 12 is connected to the four parallel connecting rods.
More specifically, the clamping mechanism further comprises a lifting piece 14, and the lifting piece 14 is connected above the connecting clamping jaw 12 so as to enable the connecting clamping jaw 12 to move vertically. The lifting part 14 can drive the connecting clamping jaws 12 to move in the vertical direction, so that the connecting clamping jaws 12 can clamp the embedding box 1 more accurately. And the connecting jaw 12 is moved to the carrier 5 and can be moved downwards to place the cassette 1 more stably on the carrier 5.
In a preferred embodiment, further specifically, the apparatus for realizing automatic embedding further comprises a box pressing member 15, and the box pressing member 15 can move vertically along the sliding groove 204. When the bottommost cassette 1 leaves the housing chamber 201, the cassette pressing member 15 can move downward along the slide groove 204 to facilitate the movement of the cassette 1 of the housing chamber 201 toward the bottom of the housing area.
It should be noted that the form of the box pressing member 15 is not limited in this embodiment, for example, the box pressing member 15 includes a slide rail extending vertically, and a pressing rod slidably connected to the slide rail. In addition, another sliding groove may be provided on the other side surface of the storage basket 2, and the cartridge holder may move in the sliding groove.
Regarding the structure of the carrier 5, more specifically, the bottom wall of the embedding box 1 is provided with the fluid hole 104, the carrier 5 includes a fixing portion 501 and a fixing buckle 502, the fixing portion 501 forms a fixing groove 5011 for inserting the embedding box 1, the bottom wall of the fixing groove 5011 is provided with a sealing protrusion 5012 inserted into the fluid hole 104, and the fixing buckle 502 is hinged to the fixing portion 501 and can be buckled to the embedding box 1.
As shown in FIG. 5, when the tissue is dehydrated, the liquid can flow out through the liquid flow holes 104 in the bottom wall of the cassette 1. As shown in fig. 12 and 13, when the embedding cassette 1 is placed in the fixing groove 5011 of the fixing part 501, the sealing protrusion 5012 can seal the liquid flow hole 104 to prevent the liquid paraffin from flowing out from the liquid flow hole 104 at the bottom of the embedding cassette 1 when dropping wax. In addition, the fixing buckle 502 can further fix the embedding box 1 on the fixing part 501, so that the fixing strength and stability of the embedding box 1 are improved.
All the embodiments in the present specification are described in a progressive manner, and the same and similar parts among the embodiments are referred to each other, and each embodiment focuses on the differences from other embodiments. In particular, for the system embodiment, since it is substantially similar to the method embodiment, the description is simple, and for the relevant points, reference may be made to the partial description of the method embodiment.
The above description is only an example of the present application and is not intended to limit the present application. Various modifications and changes may occur to those skilled in the art. Any modification, equivalent replacement, improvement or the like made within the spirit and principle of the present application shall be included in the scope of the claims of the present application.

Claims (10)

1. The method for realizing automatic embedding is characterized in that an embedding box is provided, the bottom of the embedding box protrudes downwards to form a containing cavity for containing tissues, the upper edge of the embedding box extends upwards to form a wax dripping cavity, and the top wall of the containing cavity is provided with a wax inlet communicated with the wax dripping cavity; providing an input mechanism; the method for realizing automatic embedding comprises the following steps:
step 1, a plurality of embedding boxes are located in a containing area and are sequentially stacked in the vertical direction, and in two adjacent embedding boxes, the protruding bottom of one embedding box is inserted into a wax dropping cavity of the other embedding box;
step 2, the input mechanism vertically separates the bottommost embedding box from other embedding boxes, moves the bottommost embedding box out of the containing area, and then moves the other embedding boxes downwards to the bottom of the containing area;
step 3, placing the embedding box separated from the accommodating area on a movable bearing mechanism, and enabling the bearing mechanism to drive the embedding box to move along a set path;
step 4, a heating area, a wax dripping area and a cooling area are arranged on the set path, and wax is heated and melted when the embedding box moves to the heating area; dripping wax to the embedding box when the embedding box moves to a wax dripping area; and when the embedding box moves to a cooling area, the wax block of the embedding box is cooled and formed.
2. The method for realizing automatic embedding according to claim 1, wherein the input mechanism comprises a floating member and an input member, and the step 2 comprises:
step 2.1, enabling the floating piece to be connected with the penultimate embedding box in the containing area;
and 2.2, the input piece moves towards the bottommost embedding box, meanwhile, the input piece jacks up the floating piece, the floating piece drives the penultimate embedding box and the embedding box above the penultimate embedding box to move upwards so as to separate the bottommost embedding box from other embedding boxes, and the input piece pushes the bottommost embedding box out of the containing area.
3. The utility model provides an realize equipment of automatic embedding, its characterized in that is suitable for the embedding box to carry out the embedding processing, the bottom of embedding box is the chamber that holds of protrusion in order to form the holding tissue downwards, the top edge of embedding box upwards extends in order to enclose and drips the wax chamber, the roof that holds the chamber be equipped with drip the wax hole of advancing of wax chamber intercommunication, realize that equipment of automatic embedding includes:
the storage basket forms a storage cavity for storing the embedding box, the storage cavity extends in the vertical direction, one side wall of the storage basket is provided with an outlet through which the embedding box leaves the storage cavity, the other side wall of the storage basket corresponding to the outlet is provided with an inlet communicated with the storage cavity, the side wall of the storage basket is provided with a sliding groove extending in the vertical direction, and the sliding groove is communicated with the storage cavity;
an input mechanism including an input piece and a floating piece, the input piece being located at a side of the inlet, the input piece moving between an initial position and an input position in a set direction to move an end of the input piece between the inlet and the outlet; one end of the floating piece is positioned on the side of the sliding groove to be connected with the penultimate embedding box, when the input piece is positioned at the initial position, at least part of the input piece is positioned on the side of the floating piece far away from one end of the containing basket, and when the input piece is positioned at the input position, the part of the input piece positioned on the side of the floating piece moves to the lower side of the floating piece, so that the floating piece moves upwards;
the bearing mechanism comprises a bearing piece for bearing the embedding box and a driving piece for driving the bearing piece to move along a set path;
embedding mechanism, embedding mechanism includes the edge set for the heating member of route setting, drip wax spare, cooling part, it locates to drip wax spare the heating member with between the cooling part.
4. The apparatus for realizing automatic embedding according to claim 3, wherein the wall of the wax dropping cavity of the embedding box forms a connecting wall, the connecting wall is provided with a connecting hole, the floating piece comprises a floating block and a fixed clamping jaw connected to the floating block, and the inner side of the fixed clamping jaw forms a fixed column which is inserted and matched with the connecting hole.
5. The apparatus for realizing automatic embedding according to claim 4, wherein a side of the floating block far away from the receiving basket forms a first inclined surface, and the first inclined surface is inclined downwards and extends towards a direction close to the receiving basket; the input piece comprises a box pushing part positioned below the floating block, one end, far away from the containing basket, of the box pushing part protrudes upwards to form an upper top, one side, close to the containing basket, of the upper top forms a second inclined plane, and the second inclined plane faces downwards and extends towards the direction close to the containing basket in an inclined mode; when the input piece is located at the initial position, the upper top part is located on the side of the first inclined plane.
6. The apparatus for realizing automatic embedding according to claim 4, wherein a fixing member is arranged above the floating member, and the floating member is connected to the fixing member through an elastic member, so that the floating member can move vertically relative to the fixing member.
7. The apparatus for realizing automatic embedding according to claim 3, further comprising a supporting platform and a clamping mechanism, wherein the supporting platform is arranged at the side of the outlet to bear the embedding box moved out of the containing cavity, the clamping mechanism comprises a connecting clamping jaw and a power piece, the inner side of the connecting clamping jaw is provided with a connecting column which is inserted into the connecting hole in a matching manner, and the power piece can drive the connecting clamping jaw to move between the supporting platform and the bearing piece.
8. The apparatus for realizing automatic embedding according to claim 7, wherein the clamping mechanism further comprises a lifting member connected above the connecting jaw to move the connecting jaw in a vertical direction.
9. The apparatus for realizing automatic embedding according to claim 3, further comprising a box pressing member which can move vertically along the sliding groove.
10. The apparatus for realizing automatic embedding according to claim 3, wherein the bottom wall of the embedding box is provided with a fluid hole, the carrier comprises a fixing part and a fixing buckle, the fixing part forms a fixing groove for inserting the embedding box, the bottom wall of the fixing groove is provided with a sealing protrusion inserted into the fluid hole, and the fixing buckle is hinged to the fixing part and can be buckled with the embedding box.
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Publication number Priority date Publication date Assignee Title
CN117091932A (en) * 2023-10-18 2023-11-21 北京昭衍新药研究中心股份有限公司 Automatic embedding system

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CN104697840A (en) * 2013-12-10 2015-06-10 莱卡生物系统努斯洛赫有限责任公司 Automated embedding machine, and method for embedding a histological sample
CN112278919A (en) * 2020-11-06 2021-01-29 广东博智林机器人有限公司 Material distributing and feeding device

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CN1668908A (en) * 2002-09-26 2005-09-14 比欧帕斯自动化公司 Apparatus and method for automated handling and embedding of tissue sample
CN101804726A (en) * 2010-03-30 2010-08-18 刘小欣 Pathological specimen embedding box printer
CN104697840A (en) * 2013-12-10 2015-06-10 莱卡生物系统努斯洛赫有限责任公司 Automated embedding machine, and method for embedding a histological sample
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