CN110208064B - Automatic pathological tissue treatment system - Google Patents
Automatic pathological tissue treatment system Download PDFInfo
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- CN110208064B CN110208064B CN201910576762.9A CN201910576762A CN110208064B CN 110208064 B CN110208064 B CN 110208064B CN 201910576762 A CN201910576762 A CN 201910576762A CN 110208064 B CN110208064 B CN 110208064B
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- 230000001575 pathological effect Effects 0.000 title claims abstract description 23
- 238000012545 processing Methods 0.000 claims abstract description 90
- 230000018044 dehydration Effects 0.000 claims abstract description 24
- 238000006297 dehydration reaction Methods 0.000 claims abstract description 24
- 238000012546 transfer Methods 0.000 claims abstract description 18
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims description 36
- 238000002791 soaking Methods 0.000 claims description 30
- 208000005156 Dehydration Diseases 0.000 claims description 22
- 230000007246 mechanism Effects 0.000 claims description 13
- 230000002452 interceptive effect Effects 0.000 claims description 2
- 238000000034 method Methods 0.000 description 11
- 230000008569 process Effects 0.000 description 5
- 239000012024 dehydrating agents Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 2
- 238000007598 dipping method Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000000758 substrate Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000005056 cell body Anatomy 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004043 dyeing Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 238000004018 waxing Methods 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/36—Embedding or analogous mounting of samples
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention relates to the field of pathological tissue treatment equipment, in particular to an automatic pathological tissue treatment system, which comprises a treatment basket, a plurality of treatment chambers and a plurality of treatment chambers, wherein the treatment chambers are suitable for the superposition placement of embedding boxes, and a first through hole is formed in the treatment basket at the bottom wall of each treatment chamber; a tissue dehydration element; the transfer assembly comprises a storage tank body used for placing the processing basket, a second through hole is formed in the bottom of the storage tank body corresponding to each first through hole, the transfer assembly further comprises a push rod arranged on the lower side of the storage tank body, and the push rod is arranged in a liftable manner so as to push the embedding box in the storage cavity upwards through the first through holes; the first moving part drives the treatment basket to move between the tissue dehydration part and the storage tank body; the embedding assembly comprises an embedding plate with an embedding station and an embedding piece; the second moving part moves the embedding box on the upper side of the processing basket to the embedding station, so that the tissue can be dehydrated and embedded automatically, and the problems in the prior art are effectively solved.
Description
Technical Field
The invention relates to the field of pathological tissue treatment equipment, in particular to an automatic pathological tissue treatment system.
Background
In order to accurately diagnose the occurrence and development processes and principles of various diseases, tissue specimens are often required to be taken out of a patient to obtain pathological sections, when the tissue specimens are processed, the tissue specimens to be processed are placed in an embedding box, the tissue specimens in the embedding box are subjected to fixing, dehydrating, waxing and embedding procedures, then slicing and dyeing are carried out, at present, when the tissue specimens are processed, the embedding box is manually transferred between the procedures by medical staff, the working intensity is high, part of the procedures are often time-consuming, the medical staff need to wait for a long time, and manpower resources are wasted.
The foregoing is not necessarily a prior art, and falls within the technical scope of the inventors.
Disclosure of Invention
In order to solve the technical problems, the invention provides an automatic pathological tissue treatment system which can automatically finish fixation, dehydration, wax dipping and embedding of tissues, and effectively solves the problems in the prior art.
In order to solve the problems, the invention provides an automatic pathological tissue treatment system, which comprises a treatment basket, a first through hole and a second through hole, wherein the treatment basket is opened at the top and is provided with a plurality of storage cavities, the storage cavities are suitable for the superposition placement of embedding boxes, and the treatment basket at the bottom wall of the storage cavities is provided with the first through hole; a tissue dehydration element; the transfer assembly comprises a storage groove body used for placing the processing basket, a second through hole is formed in the bottom of the storage groove body corresponding to each first through hole, and the transfer assembly further comprises a push rod arranged on the lower side of the storage groove body, wherein the push rod can be arranged in a lifting manner so as to push the embedding box in the storage cavity upwards through the first through holes; the first moving part drives the treatment basket to move between the tissue dehydration part and the storage tank body; the embedding assembly comprises an embedding plate with an embedding station and an embedding piece; and the second moving part moves the embedding box at the upper side of the processing basket to the embedding station.
Further, the transfer assembly further comprises: the base plate is provided with a processing basket placing station and an embedding box taking-out station, a sliding rail is arranged at the top of the base plate, and the storage groove body is arranged on the sliding rail in a sliding manner so as to switch between the processing basket placing station and the embedding box taking-out station; the upper shielding plate is arranged at the upper side of the embedding box taking-out station, a third through hole for the embedding box to pass through is formed in the upper shielding plate, and the side wall of the third through hole is inclined obliquely inwards from bottom to top so that the top surface profile of the third through hole is smaller than the bottom surface profile of the third through hole; the driving piece drives the storage groove body to be switched between the processing basket placing station and the embedding box taking-out station.
Further, a cover plate is further arranged on the upper side of the treatment basket, rib plates are formed by extending downwards on two sides of the cover plate, when the treatment basket is placed in the storage groove body, the rib plates are consistent with the direction of the sliding rail, and the projection of the rib plates and the upper shielding plate in the axis direction of the sliding rail is partially overlapped; the rib plate is provided with a sliding groove, the processing basket is provided with a guide post which is arranged in the sliding groove in a sliding manner, the guide post is positioned at one end of the processing basket, which is away from the upper shielding plate, the cover plate slides to the position, when the guide post is positioned at one end of the sliding groove, which is towards the upper shielding plate, the cover plate can rotate around the guide post to be parallel to the side wall of the processing basket, and the upper end of the cover plate is not higher than the upper end of the processing basket.
Further, the driving piece comprises a rack and a first motor, wherein the rack is connected with the storage tank body, and a gear meshed with the rack is arranged on a rotating shaft of the first motor.
Further, the processing basket is provided with two storage cavities, and the substrate is provided with two embedding box taking-out stations; the transfer assembly comprises two connected push rods, the two push rods respectively correspond to one of the embedding box taking-out stations, and the processing basket is respectively positioned at the two embedding box taking-out stations, and the two push rods respectively correspond to the two storage cavity positions.
Further, the tissue dehydration piece comprises a formalin soaking tank, a dehydration tank and a wax soaking tank which are sequentially arranged at intervals.
Further, formalin soaking tank, dewatering tank, wax soaking tank, the linear interval of storage tank body are arranged, the upside of handling basket is formed with the lifting hook, first moving part includes: the first guide rail is arranged along the arrangement direction of the formalin soaking tank, the dewatering tank and the wax soaking tank; the second guide rail is arranged on the first guide rail in a sliding manner and is vertically arranged; the picking and placing hook comprises a sliding block which is arranged on the second guide rail in a sliding manner and an L-shaped lifting hook which is connected with the sliding block.
Further, the processing system further comprises a horizontally arranged hanging rod arranged on the upper side of the storage tank body, so that the lifting hook can be hung on the hanging rod.
Further, the second moving part comprises a triaxial moving mechanism arranged on one side of the embedding plate, and an electric clamping jaw is arranged at the moving end of the triaxial moving mechanism.
Further, the embedding component comprises a storage plate arranged on one side of the embedding plate, a plurality of embedding box storage grooves are formed in the storage plate, and the embedding box storage grooves are arranged towards one end of the embedding plate in an open mode.
The invention has the beneficial effects that the invention provides an automatic pathological tissue treatment system which can automatically fix, dehydrate, dip wax and embed tissues, and effectively solves the problems in the prior art.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention and do not constitute a limitation on the invention. In the drawings:
FIG. 1 is a schematic diagram of an embodiment of the present invention;
fig. 2 is a schematic view showing the structure of the formalin immersion tank in the embodiment shown in fig. 1;
FIG. 3 is a schematic view of the embodiment of FIG. 1 with a cover plate closing the processing basket;
FIG. 4 is a schematic view of the embodiment of FIG. 1 with the lid panel open to the process basket;
FIG. 5 is a first perspective view of the transfer assembly of the embodiment of FIG. 1;
FIG. 6 is a second perspective view of the transfer assembly of the embodiment of FIG. 1;
FIG. 7 is a schematic diagram of the embodiment of FIG. 1;
FIG. 8 is a schematic view of the structure of the embedding assembly in the embodiment shown in FIG. 1;
FIG. 9 is a schematic side cross-sectional view of the transfer assembly of the embodiment of FIG. 1;
wherein: 1. a treatment basket; 2. embedding a box; 3. a storage tank; 4. a push rod; 5. embedding plates; 6. an embedding station; 7. embedding pieces; 8. a substrate; 9. placing the processing basket into a station; 10. an embedding box taking-out station; 11. an upper shield; 12. a cover plate; 13. rib plates; 14. a chute; 15. a guide post; 16. a rack; 17. a first motor; 18. a gear; 19. a formalin soaking tank; 20. a dewatering tank; 21. a wax dipping tank; 22. a lifting hook; 23. a first guide rail; 24. a second guide rail; 25. taking and placing hooks; 2501. a slide block; 2502. a lifting hook; 26. a hanging rod; 27. a triaxial movement mechanism; 28. an electric clamping jaw; 29. a storage plate; 30. embedding box storage tank.
Detailed Description
In order to more clearly illustrate the general inventive concept, reference will be made in the following detailed description, by way of example, to the accompanying drawings.
It should be noted that in the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention, however, the present invention may be practiced in other ways than as described herein, and therefore the scope of the present invention is not limited by the specific embodiments disclosed below.
In addition, in the description of the present invention, it should be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the drawings, are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a specific orientation, be configured and operated in a specific orientation, and thus should not be construed as limiting the present invention.
In the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," "secured," and the like are to be construed broadly, and may be, for example, fixedly connected, detachably connected, or integrally formed; can be directly connected or indirectly connected through an intermediate medium, and can be communicated with the inside of two elements or the interaction relationship of the two elements. However, it is noted that a direct connection indicates that two bodies connected together do not form a connection relationship by an excessive structure, but are connected to form a whole by a connection structure. The specific meaning of the above terms in the present invention can be understood by those of ordinary skill in the art according to the specific circumstances.
In the present invention, unless expressly stated or limited otherwise, a first feature "up" or "down" a second feature may be the first and second features in direct contact, or the first and second features in indirect contact via an intervening medium. In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms are not necessarily directed to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
In the invention, as shown in figures 1-9, an automatic pathological tissue treatment system is provided, which comprises a treatment basket 1, a first through hole and a second through hole, wherein the top of the treatment basket is provided with a plurality of storage cavities, the storage cavities are suitable for the superposition placement of the embedding boxes 2, and the treatment basket 1 at the bottom wall of the storage cavities is provided with the first through hole; a tissue dehydration element; the transfer assembly comprises a storage tank body 3 for placing the processing basket 1, a second through hole is formed in the bottom of the storage tank body 3 corresponding to each first through hole, the transfer assembly further comprises a push rod 4 arranged on the lower side of the storage tank body 3, and the push rod 4 is arranged in a liftable manner so as to push the embedding box 2 in the storage cavity upwards through the first through holes; the first moving part drives the treatment basket 1 to move between the tissue dehydration part and the storage tank body 3; the embedding assembly comprises an embedding plate 5 with an embedding station 6 and an embedding piece 7; and the second moving part moves the embedding box 2 on the upper side of the processing basket 1 to the embedding station 6.
When the treatment system is used, the embedding box 2 with pathological tissues is placed in the tissue dehydration piece, the tissue dehydration piece carries out dehydration treatment on the pathological tissues in the embedding box 2, after the tissue dehydration piece is operated, the first moving piece moves the treatment basket 1 into the storage tank body 3, then the push rod 4 is lifted and passes through the second through hole and the first through hole, the embedding box 2 in the storage cavity is jacked up upwards, so that the uppermost embedding box 2 leaks out of the upper side of the treatment basket 1, then the embedding box 2 on the upper side of the treatment basket 1 is moved to the embedding station 6 through the second moving piece, and the embedding operation treatment is carried out through the embedding piece 7.
Therefore, the treatment system can automatically complete the operations of dehydration and embedding after the treatment basket 1 is placed in the tissue dehydration piece, and has high automation degree without waiting by staff.
In addition, according to the processing system disclosed by the invention, the embedding boxes 2 in the processing basket 1 can be ejected to the upper side of the processing basket 1 one by one through the transferring assembly, and then the embedding boxes 2 can be moved to the embedding station 6 one by one through the first moving part to carry out embedding operation, so that workers do not need to separate the embedding boxes 2 one by one, after the processing basket 1 is moved to the storage tank body 3 by the first moving part, each embedding box 2 can be automatically moved to the embedding station 6 to carry out embedding operation, and the labor intensity of the workers is greatly reduced.
In addition, since the present invention enables the uppermost cassette 2 to be easily separated from the process basket 1 and easily separated from the lower cassette 2 when the first moving member moves the uppermost cassette 2 by ejecting the cassettes 2 one by one from the upper side of the process basket 1 at the transfer assembly.
In particular, the embedded boxes 2 are lifted one by one through the lifting of the push rod 4, so that the embedded boxes 2 can be ensured to stably move to the appointed position on the upper side of the processing basket 1, and further, the second moving part can be ensured to accurately acquire the embedded box 2 on the uppermost side.
Further optimized is that the transfer assembly further comprises: the base plate 8 is provided with a treatment basket placing station 9 and an embedding box taking-out station 10, a sliding rail is arranged at the top of the base plate 8, and the storage tank body 3 is arranged on the sliding rail in a sliding manner so as to switch between the treatment basket placing station 9 and the embedding box taking-out station 10; the upper shielding plate 11 is arranged at the upper side of the embedding box taking-out station 10, a third through hole for the embedding box 2 to pass through is formed in the upper shielding plate 11, and as shown in fig. 9, the side wall of the third through hole is inclined obliquely inwards from bottom to top so that the top surface profile of the third through hole is smaller than the bottom surface profile of the third through hole; the upper shield 11 restricts upward movement of the processing basket 1 when the processing basket 1 is at the cassette removal station 10; the driving piece drives the storage tank body 3 to switch between the treatment basket placing station 9 and the embedding box taking-out station 10.
When the movable type storage box is used, the storage box body 3 is located at the processing basket placing station 9, the first movable piece moves the processing basket 1 into the storage box body 3, then the driving piece moves the storage box body 3 to the embedding box taking-out station 10, the embedding box 2 is jacked up upwards through the push rod 4, and the embedding box 2 is moved through the first movable piece.
Wherein, because the lateral wall slope of third through-hole sets up, can play the guide effect when upwards jack-up embedding box 2, the bottom surface profile of third through-hole is great, reduces the requirement to the storage tank body remove the removal precision of taking out the station to embedding box 2, and when embedding box 2 moved out the upside of upper shield 11, the top surface profile of third through-hole is less, can inject the position of embedding box 2, the second moving part of being convenient for acquires embedding box 2.
Through having set up the upper shield 11, can deposit the cell body 3 and remove to the embedding box and take out station 10 after, when push rod 4 jack-up embedding box 2 upwards, through the upper shield 11 restriction processing basket 1 upward movement, prevent that embedding box 2 from driving processing basket 1 and upwards moving together, and then can prevent that processing basket 1 from interfering the operation of second moving member. Further, by providing the upper shutter 11, the position of the second moving member to acquire the cassette 2 can be determined by the upper shutter 11, thereby facilitating control of the lifting stroke of the push rod 4.
In a preferred embodiment, in order to prevent the embedding box 2 from being separated from the processing basket 1 when the embedding box 2 in the processing basket 1 is processed in the dewatering element, the upper side of the processing basket 1 is further provided with a cover plate 12, two sides of the cover plate 12 extend downwards to form a rib plate 13, when the processing basket 1 is placed in the storage tank body 3, the rib plate 13 is consistent with the direction of the sliding rail, and the projection of the rib plate 13 and the upper shielding plate 11 in the axis direction of the sliding rail is partially overlapped; the rib plate 13 is provided with a chute 14, the treatment basket 1 is provided with a guide post 15 which is arranged in the chute 14 in a sliding manner, the guide post 15 is positioned at one end of the treatment basket 1, which is away from the upper shielding plate 11, the cover plate 12 slides to the position, when the guide post 15 is positioned at one end of the chute 14, which is toward the upper shielding plate 11, the cover plate 12 can rotate around the guide post 15 to be parallel to the side wall of the treatment basket 1, and the upper end of the cover plate 12 is not higher than the upper end of the treatment basket 1.
By providing the cover plate 12, the treatment basket 1 can be closed, so that the embedding cassette 2 can be prevented from moving upward out of the outside of the treatment basket 1 when the first moving member transports the treatment basket 1 in assembling the dehydrating member. After the processing basket 1 is placed in the storage tank body 3, when the storage tank body 3 is moved to the embedding box taking-out station 10 through the driving piece, the upper shielding plate 11 is abutted with the cover plate 12, so that the cover plate 12 slides relative to the processing basket 1, when the cover plate 12 slides to the end, where the guide post 15 faces the upper shielding plate 11, of the guide post 15, the whole cover plate 12 rotates around the guide post 15 and rotates until the cover plate 12 is parallel to the side wall of the processing basket 1, at the moment, the cover plate 12 is shielded by the processing basket 1 in the horizontal direction, the cover plate 12 does not influence the processing basket 1 to enter the lower side of the upper shielding plate 11, meanwhile, the cover plate 12 does not seal the processing basket 1 any more, and after the processing basket 1 moves to the embedding box taking-out station 10, the next operation can be performed. Therefore, through the cover plate 12, the embedded box 2 in the processing basket 1 can be closed, the embedded box 2 is prevented from being separated, the cover plate 12 can be switched to a state of not closing the processing basket 1 when the driving piece drives the storage groove body 3 to move, and the processing basket is realized without adding electric elements, so that the structure is simple and stable.
In the preferred embodiment, as shown in the figure, further specifically, the driving member includes a rack 16 connected to the storage tank 3, and a first motor 17, and a gear 18 meshed with the rack 16 is disposed on a rotating shaft of the first motor 17.
Of course, it should be understood that the structural form of the driving member is not limited thereto, and may have other forms, for example, the driving member may be an electric telescopic rod, or a form of screw-nut engagement.
It should be noted that, in the illustrated embodiment, the processing basket 1 is provided with two storage chambers, and the base plate 8 is provided with two cassette extracting stations 10; the transfer assembly comprises two connected push rods 4, the two push rods 4 respectively correspond to one of the embedding box taking-out stations 10, and the processing basket 1 is respectively positioned at the two embedding box taking-out stations 10, and the two push rods 4 respectively correspond to the two storage cavity positions.
As shown in the figure, the lower ends of the two push rods 4 are simultaneously connected with a connecting plate, the connecting plate is screwed on a screw rod, the screw rod is driven to rotate by a lifting motor, and the screw rod is simultaneously connected with the frame rotation of the whole system, so that the connecting plate slides on the screw rod when the lifting motor rotates, and the lifting of the two push rods 4 can be realized. When the storage tank body 3 moves to the embedded box taking-out station 10 close to the processing basket putting-in station 9, the two push rods 4 simultaneously move upwards, one push rod 4 can push out the embedded box 2 in the storage cavity at the corresponding position, the other push rod 4 does not have the processing basket 1, after the embedded box 2 in the processing basket 1 is completely taken out, the push rod 4 is lowered, the storage tank body 3 is moved to the other embedded box taking-out station 10 through the driving piece, and then the push rod 4 is lifted, so that the embedded box 2 in the other storage cavity of the processing basket 1 can be pushed out.
From this, it can be seen that the lifting of the two push rods 4 can be completed through one lifting motor, and through setting up two embedding box taking out stations 10, the embedding boxes 2 in the two storage cavities can be taken out respectively, so that more embedding boxes 2 can be placed in one processing basket 1, the tissue processing efficiency of the whole system is increased, and the lifting of each push rod 4 can be realized by adopting fewer electrical elements.
Of course, the connection plate may be moved by another lifting power unit, for example, by connecting a lifting rack 16 to the connection plate, arranging a lifting motor on one side of the lifting rack 16, and arranging a gear 18 engaged with the lifting rack 16 on a rotating shaft of the lifting motor.
Of course, in alternative embodiments, only one storage chamber may be provided in the processing basket 1, only one cassette removal station 10 and one push rod 4. Alternatively, a plurality of storage chambers may be provided in the processing basket 1, only one station 10 for taking out the embedded box is provided, a plurality of push rods 4 are provided corresponding to each storage chamber, each push rod 4 is driven to lift by a lifting power unit, for example, each push rod 4 is driven to move by an electric telescopic rod.
In the illustrated embodiment, further specifically, the tissue dehydrator comprises a formalin soaking tank 19, a dehydration tank 20, and a wax soaking tank 21 which are sequentially disposed at intervals. The tissue in the embedding cassette 2 can thus be dehydrated in the dehydration tank 20 by formalin-soaking the tissue in the embedding cassette 2 in the formalin-soaking tank 19, and then wax-soaking in the wax-soaking tank 21, during which the processing basket 1 is moved by the first moving member from between the formalin-soaking tank 19, the dehydration tank 20, and the wax-soaking tank 21.
In a preferred embodiment, the treatment system of the present invention further comprises a formalin feeding structure, a dehydrating agent feeding mechanism and a wax feeding mechanism, wherein the formalin feeding structure specifically comprises a formalin feeding pipeline and a formalin feeding pump, the dehydrating agent feeding mechanism specifically comprises a dehydrating agent feeding pipeline and a dehydrating agent feeding pump, and the wax feeding mechanism comprises a wax feeding pipeline and a wax feeding pump. Wherein, the formalin soaking tank 19, the dewatering tank 20 and the wax soaking tank 21 are respectively provided with a discharge pipe, and each discharge pipe is respectively provided with a discharge valve.
Of course, other forms of tissue dewatering elements are possible, such as existing integrated tissue dewatering machines.
In the illustrated embodiment, further specifically, the formalin soaking tank 19, the dewatering tank 20, the wax soaking tank 21, and the storage tank body 3 are arranged at linear intervals, the hanging hooks 22 are formed on the upper side of the processing basket 1, and the first moving member includes: a first guide rail 23 arranged along the arrangement direction of the formalin soaking tank 19, the dewatering tank 20 and the wax soaking tank 21; the second guide rail 24 is slidably arranged on the first guide rail 23 and is vertically arranged; the pick-and-place hook 25 includes a slider 2501 slidably disposed on the second rail 24 and an L-shaped lifting hook 2502 connected to the slider 2501.
As shown in the drawing, the first guide rail 23 is horizontally arranged on the upper side of the formalin soaking tank 19, the second guide rail 24 is vertically arranged, a picking and placing hook 25 is vertically arranged on the second guide rail 24 in a sliding manner, as shown in the drawing, lead screws are respectively arranged in the first guide rail 23 and the second guide rail 24, each lead screw at the corresponding position of the first guide rail 23 and the second guide rail 24 is respectively connected with one motor, the second guide rail 24 is connected with the lead screw in the first guide rail 23 in a screwing manner, and the sliding block 2501 is connected with the lead screw in the second guide rail 24 in a screwing manner.
As shown in the figure, the middle position of the top of the processing basket 1 is provided with a lifting hook 22, the lifting hook 22 is in an inverted L shape, the lifting hook 2502 is in an L shape, when the processing basket is used, in the state shown in the figure, the second guide rail 24 is moved to the left side of the processing basket 1, then the sliding block 2501 is moved downwards, the lower end of the lifting hook 2502 is positioned at the lower side of the lifting hook 22, the second guide rail 24 is moved rightwards, the lower end of the lifting hook 2502 is moved to the right below the lifting hook 22, the sliding block 2501 is moved upwards again, the processing basket 1 can be lifted, the processing basket 1 can be moved to the next procedure position in the horizontal direction, for example, after the processing basket 1 is moved to the upper side of the storage tank body 3, the sliding block 2501 is moved downwards, the processing basket 1 can be placed into the storage tank body 3, and then the second guide rail 24 is moved leftwards, so that the lifting hook 22 and the lifting hook 2502 can be separated.
In a preferred embodiment, in order to process a plurality of processing baskets 1 at a time, a plurality of processing baskets 1 may be placed in each of the formalin soaking tank 19 and the wax soaking tank 21, and a plurality of dewatering tanks 20 may be further provided, and since only a small number of processing baskets 1 may be placed in the storage tank 3, the processing system further includes a horizontal hanging rod 26 disposed at an upper side of the storage tank 3, so that the hanging hook 22 may be hung on the hanging rod 26. As shown, after the cassette 2 in the processing basket 1 is completely removed, the processing basket 1 can be removed from the storage tank 3 by the lifting hook 2502, and then the processing basket 1 is hung on the hanging rod 26.
In the illustrated embodiment, further specifically, the second moving member includes a triaxial moving mechanism 27 disposed on one side of the embedding plate 5, and an electric clamping jaw 28 is disposed at a moving end of the triaxial moving mechanism 27. As shown in the figure, the triaxial movement structure can be selected from the existing triaxial movement mechanism 27, the triaxial movement mechanism 27 comprises a transverse sliding rail transversely arranged on one side of the embedding plate 5, a vertical sliding rail is slidably arranged on the transverse sliding rail, a horizontal sliding rail is slidably arranged on the vertical sliding rail, a sliding seat is arranged on the horizontal sliding rail, and an electric clamping jaw 28 is connected with the sliding seat. Wherein, all be equipped with the lead screw in horizontal slide rail, vertical slide rail, horizontal slide rail, each lead screw links to each other with a motor respectively from this through motor drive each lead screw rotation for vertical slide rail lateral shifting, horizontal slide rail vertical shifting, but the slide horizontal along with horizontal slide rail vertically direction remove, and then realize triaxial and remove.
It can be seen that the motorized jaw 28 of the present invention is capable of moving to the upper side of the upper shield 11, gripping the uppermost cassette 2, and moving the gripped cassette 2 to the embedding station 6.
It should be further noted that, a plurality of embedding stations 6 are distributed on the embedding plate 5 at intervals to place the embedding boxes 2, and the embedding pieces 7 are existing wax dropping heads, wherein the special triaxial movement structure drives the wax dropping heads to move.
It should be noted that the form of the first moving member and the second moving member is not a limitation of the present invention, and in alternative embodiments, the first moving member and the second moving member may take other forms, such as a robot.
Further optimized is that the embedding assembly comprises a storage plate 29 arranged on one side of the embedding plate 5, a plurality of embedding box storage grooves 30 are formed in the storage plate 29, and the embedding box storage grooves 30 are arranged towards one end of the embedding plate 5 in an open mode. As shown in the figure, after the embedding operation of the embedding cassette 2 is completed at the embedding station 6, the embedded embedding cassette 2 is clamped by the electric clamping jaw 28, then the embedding cassette 2 is moved into the embedding cassette storage groove 30, and then the embedding cassette 2 is released by the electric clamping jaw 28, so that the embedding operation can be continuously performed without occupying the embedding station 6.
It should be noted that the processing system of the present invention further includes a frame and a housing, the storage board is fixed to the housing, in fig. 1, for illustrating the internal structure, both the housing and the storage board are not drawn, and in fig. 7, the storage board is drawn.
In this specification, each embodiment is described in a progressive manner, and identical and similar parts of each embodiment are all referred to each other, and each embodiment mainly describes differences from other embodiments. In particular, for system embodiments, since they are substantially similar to method embodiments, the description is relatively simple, as relevant to see a section of the description of method embodiments.
The foregoing is merely exemplary of the present application and is not intended to limit the present application. Various modifications and changes may be made to the present application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc. which are within the spirit and principles of the present application are intended to be included within the scope of the claims of the present application.
Claims (8)
1. An automated pathological tissue treatment system, comprising:
the top of the treatment basket is opened, the treatment basket is provided with a plurality of storage cavities, the storage cavities are suitable for the superposition placement of embedding boxes, and a first through hole is formed in the treatment basket at the bottom wall of the storage cavity;
a tissue dehydration element;
the transfer assembly comprises a storage tank body used for placing the processing basket, a second through hole is formed in the bottom of the storage tank body corresponding to each first through hole, the transfer assembly further comprises a push rod arranged on the lower side of the storage tank body, and the push rod can be arranged in a lifting manner so as to push the embedding boxes in the storage cavity upwards through the second through holes and the first through holes, so that the embedding boxes can be jacked up one by one;
the first moving piece drives the treatment basket to move between the tissue dehydration piece and the storage tank body;
the embedding assembly comprises an embedding plate with an embedding station, an embedding piece and a storage plate arranged on one side of the embedding plate;
the second moving piece moves the embedding box on the upper side of the processing basket to the embedding station;
when the treatment system is used, the embedding box with pathological tissues is placed in the tissue dehydration piece, the tissue dehydration piece carries out dehydration treatment on the pathological tissues in the embedding box, after the tissue dehydration piece finishes operation, the first moving piece moves the treatment basket into the storage tank body, then the push rod is lifted and passes through the second through hole and the first through hole, the embedding box in the storage cavity is lifted upwards, so that the embedding box at the uppermost side leaks out of the upper side of the treatment basket, and then the embedding box at the upper side of the treatment basket is moved to an embedding station through the second moving piece to carry out embedding operation treatment through the embedding piece;
the transfer assembly further comprises:
the base plate is provided with a processing basket placing station and an embedding box taking-out station, a sliding rail is arranged at the top of the base plate, and the storage groove body is arranged on the sliding rail in a sliding manner so as to switch between the processing basket placing station and the embedding box taking-out station;
the upper shielding plate is arranged at the upper side of the embedding box taking-out station, a third through hole for the embedding box to pass through is formed in the upper shielding plate, and the side wall of the third through hole is inclined obliquely inwards from bottom to top so that the top surface profile of the third through hole is smaller than the bottom surface profile of the third through hole;
the driving piece drives the storage tank body to switch between the processing basket placing station and the embedding box taking-out station; through setting up the upper shielding plate, after the storage tank body moves to the station for taking out the embedded box, when the push rod upwards jacks up the embedded box, the upper shielding plate limits the upward movement of the processing basket, so as to prevent the embedded box from moving upwards along with the processing basket, further prevent the processing basket from interfering with the operation of the second moving part, and the position of the embedded box can be obtained by determining the second moving part through the upper shielding plate, thereby being convenient for controlling the lifting stroke of the push rod;
the upper side of the treatment basket is also provided with a cover plate, two sides of the cover plate extend downwards to form a rib plate, when the treatment basket is placed in the storage tank body, the rib plate is consistent with the direction of the sliding rail, and the projection of the rib plate and the upper shielding plate in the axis direction of the sliding rail is partially overlapped; the rib plate is provided with a chute, the treatment basket is provided with a guide post which is arranged in the chute in a sliding manner, the guide post is positioned at one end of the treatment basket, which is away from the upper shielding plate, the cover plate slides to the position, when the guide post is positioned at one end of the chute, which is towards the upper shielding plate, the cover plate can rotate around the guide post to be parallel to the side wall of the treatment basket, and the upper end of the cover plate is not higher than the upper end of the treatment basket;
through setting up the apron, can seal the processing basket, thereby in the equipment dewatering piece, when the first moving member transported the processing basket, can prevent to embed the outside that the box upwards moved out the processing basket, after putting into the storage tank body with the processing basket, when taking out the station to the embedding box through the storage tank body of driving piece removal storage tank body, because butt between upper shield and the apron, make the apron slide for the processing basket, when the apron slides to the guide post and is in the one end of spout orientation upper shield, whole apron rotates around the guide post, and rotate to the lateral wall parallel of apron and processing basket, at this moment, the apron is sheltered from by the processing basket in the horizontal direction, the apron does not influence the processing basket and gets into the upper shield downside, simultaneously, the apron no longer seals the processing basket, after the processing basket removes to the box and takes out the station, can carry out next operation.
2. An automated pathological tissue treatment system according to claim 1, wherein the driving member comprises a rack connected with the storage tank body and a first motor, and a gear meshed with the rack is arranged on a rotating shaft of the first motor.
3. An automated pathological tissue treatment system according to claim 1, wherein the treatment basket is provided with two storage chambers and the base plate is provided with two cassette removal stations; the transfer assembly comprises two connected push rods, the two push rods respectively correspond to one of the embedding box taking-out stations, and the processing basket is respectively positioned at the two embedding box taking-out stations, and the two push rods respectively correspond to the two storage cavity positions.
4. An automated pathological tissue treatment system according to claim 1, wherein the tissue dewatering element comprises a formalin soaking tank, a dewatering tank, and a wax soaking tank arranged in sequence at intervals.
5. The automated pathological tissue treatment system according to claim 4, wherein the formalin soaking tank, the dewatering tank, the wax soaking tank, and the storage tank are arranged at a linear interval, a hanging hook is formed on an upper side of the treatment basket, and the first moving member comprises:
the first guide rail is arranged along the arrangement direction of the formalin soaking tank, the dewatering tank and the wax soaking tank;
the second guide rail is arranged on the first guide rail in a sliding manner and is vertically arranged;
the picking and placing hook comprises a sliding block which is arranged on the second guide rail in a sliding manner and an L-shaped lifting hook which is connected with the sliding block.
6. The automated pathological tissue treatment system according to claim 5, further comprising a cross-bar disposed on an upper side of the storage tank such that the hooks can be hooked on the bar.
7. An automated pathological tissue treatment system according to claim 1, wherein the second moving member comprises a triaxial movement mechanism arranged on one side of the embedding plate, and wherein an electric clamping jaw is arranged at the moving end of the triaxial movement mechanism.
8. The automated pathological tissue treatment system according to claim 6, wherein the storage plate is formed with a plurality of cassette storage slots, the cassette storage slots being open toward one end of the plate.
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| CN111077007B (en) * | 2019-12-30 | 2024-09-10 | 山西医科大学第二医院 | Real-time fixing device and method for frozen pathological tissue after sampling |
| CN113432939B (en) * | 2020-12-09 | 2023-08-25 | 山东骏腾医疗科技有限公司 | Automatic tissue dehydrator for rapid pathology |
| CN113340697B (en) * | 2021-05-31 | 2023-10-20 | 佳木斯大学 | Auxiliary device for preparing pathological section of tumor tissue and use method thereof |
| CN113310771B (en) * | 2021-06-29 | 2022-06-24 | 江西金域医学检验所有限公司 | Improved generation self-propelled medical tissue dehydration basket |
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