CN114404502A - 一种治疗过敏性鼻炎与慢性鼻炎的中药组合物及制作方法 - Google Patents
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物及制作方法 Download PDFInfo
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- CN114404502A CN114404502A CN202210088034.5A CN202210088034A CN114404502A CN 114404502 A CN114404502 A CN 114404502A CN 202210088034 A CN202210088034 A CN 202210088034A CN 114404502 A CN114404502 A CN 114404502A
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Abstract
本发明公开了一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，属于鼻炎外用药技术领域包括以下重量份数的组分：鲜猕猴桃根、鲜半枝莲、干半枝莲、白英、细辛、辛荑花、深绿卷柏、山豆根、白花蛇舌草、半边莲、鸭跖草、苍耳子、苍术、白芷、鹅不食草、鱼腥草、荜茇、甘草、荆芥、薄荷、淡豆豉、防风、升麻、金银花、蒲公英、紫花地丁、金荞麦、野菊花、地苦胆、瓜子金，还公开了一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，其中药组合物能同时治疗过敏性鼻炎和慢性鼻炎，同时缓解这两种病症，而且治疗效果显著，没有副作用，疗效时间保持长久，可达3‑5年。
Description
技术领域
本发明属于鼻炎外用药技术领域，具体涉及一种治疗过敏性鼻炎与慢性鼻炎的中药组合物及制作方法。
背景技术
过敏性鼻炎又叫季节性鼻炎，好在春季发病，有明显的过敏源。只有当接触过敏源时才发病，状态为突发性喷涕、鼻塞、流涕等；而慢性鼻炎是鼻腔粘膜的慢性充血水肿造成鼻塞、流涕，而很少有喷涕等症状。过敏性鼻炎和慢性鼻炎在临床上区别是很大的。过敏性鼻炎患者主要的症状就是打喷嚏、流清水样分泌物；检查的时候，鼻腔黏膜苍白、水肿。慢性鼻炎主要就是鼻塞，鼻腔分泌物比较黏稠，在检查的时候，鼻甲是充血肿大的。在西医治疗方面，过敏性鼻炎主要是使用鼻喷的激素，比如内舒拿或者雷诺考特喷鼻子，症状严重的，可以配合口服抗过敏的药物治疗。慢性鼻炎主要是使用血管收缩的药物，比如达芬霖喷鼻子。
但以上西医药物虽然可以控制病情，但是停药即发，有一定的副作用，而且疗效也不是十分理想，易复发，而中医药是近年治疗鼻炎的趋势，根据中医辩证方法进行治疗，临床治疗效果显著且副作用极小，疗效可以保持很长时间。
过敏性鼻炎在中医辩证中多属肺气虚弱、肺脾气虚、肾元亏虚证型，慢性鼻炎在中医辩证中认为是由于肺气虚弱，邪滞鼻窍而致气化功能不健，易受寒邪侵袭，失去清肃功能，以致邪滞鼻窍；或脾气虚弱，运化不健，失去升降浊之职，湿浊滞留鼻窍，壅阻脉络。这两种鼻炎的中医病因病机不同，则在治疗过程中应用的中医辩证治疗法也不同，而且由于其病因不同，这两种鼻炎病症很难由一个中药配方同时治疗，但是目前鼻炎患者有较大部分都是两种鼻炎症状都存在，现有已知的中药配方只能针对一种鼻炎进行治疗，无法同时治疗。
发明内容
针对现有技术中存在的问题，本发明的目的在于提供种治疗过敏性鼻炎与慢性鼻炎的中药组合物及制作方法，其中药组合物能同时治疗过敏性鼻炎和慢性鼻炎，同时缓解这两种病症，而且治疗效果显著，没有副作用，疗效时间保持长久，可达3-5年。
为实现以上目的，本发明采取的技术方案是：
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，包括以下重量份数的组分：鲜猕猴桃根30-75份、鲜半枝莲20-50份、干半枝莲15-30份、白英15-30份、细辛3-8份、辛荑花10-15份、深绿卷柏15-20份、山豆根10-20份、白花蛇舌草10-15份、半边莲15-20份、鸭跖草15-30份、苍耳子10-20份、苍术10-20份、白芷10-20份、鹅不食草10-20份、鱼腥草10-15份、荜茇10-20份、甘草5-10份、荆芥10-25份、薄荷15-30份、淡豆豉10-20份、防风5-20份、升麻10-20份、金银花10-15份、蒲公英10-15份、紫花地丁10-15份、金荞麦15-25份、野菊花10-20份、地苦胆5-10份、瓜子金10-20份。
优选地，包括以下重量份数的组分：鲜猕猴桃根50-75份、鲜半枝莲35-50份、干半枝莲20-30份、白英20-30份、细辛3-5份、辛荑花10-13份、深绿卷柏18-20份、山豆根10-15份、白花蛇舌草12-15份、半边莲15-19份、鸭跖草15-25份、苍耳子10-15份、苍术10-15份、白芷10-15份、鹅不食草15-20份、鱼腥草13-15份、荜茇10-15份、甘草5-8份、荆芥10-20份、薄荷15-20份、淡豆豉15-20份、防风5-10份、升麻10-15份、金银花13-15份、蒲公英12-15份、紫花地丁12-15份、金荞麦15-20份、野菊花10-15份、地苦胆5-7份、瓜子金10-15份。
优选地，包括以下重量份数的组分：鲜猕猴桃根75份、鲜半枝莲50份、干半枝莲30份、白英30份、细辛3份、辛荑花10份、深绿卷柏15份、山豆根10份、白花蛇舌草15份、半边莲15份、鸭跖草15份、苍耳子10份、苍术10份、白芷10份、鹅不食草15份、鱼腥草15份、荜茇10份、甘草5份、荆芥10份、薄荷15份、淡豆豉15份、防风8份、升麻10份、金银花15份、蒲公英15份、紫花地丁15份、金荞麦15份、野菊花10份、地苦胆5份、瓜子金10份。
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，包括以下步骤：
A.按重量份数计，将上述中药材成分各自放入粉粹机中粉碎成粗粉，再放入超微粉
碎设备中继续进行粉碎得到细粉；
B.将步骤A得到的各草药细粉混合，放入高粱酒中搅拌均匀，静置，之后再放入活性炭，10-12h后将活性炭取出，剩余的液体即得到的中药组合物。
进一步地，所述步骤A中粗粉粒径在30-80目，细粉粒径在250目以上。
进一步地，所述步骤B中高粱酒与总中药粉末重量比为7-10:1。
进一步地，所述步骤B中高粱酒度数为40-50°。
进一步地，所述步骤B中静置时间为3-5d。
本发明的有益效果是：(1)本发明制作的中药组合物能同时治疗过敏性鼻炎和慢性鼻炎，同时缓解这两种病症，而且治疗效果显著，没有副作用，疗效时间保持长久，可达3-5年；
(2)本发明在制作过程中将中药成分进行超微粉碎，是为了保证中药有效成分更好的溶入高粱酒中，提高成分浓度，在治疗过敏性鼻炎与慢性鼻炎时快速起效果；在步骤B中加入的高粱酒为高度酒，在帮助中药材有效成分溶出的的同时，在涂擦患处时会刺激皮肤，反而会造成症状加重，因此，加入活性炭可以吸附酒精中甲醇，降低酒精度数，避免因度数过高而导致出现的副作用；
(3)本发明遵循中医辩证原则，主治润肺，其中，以瓜子金、野菊花、金银花、蒲公英、白花蛇舌草和紫花地丁为君药，有清热解毒、消炎消肿、顺气润肺之功效，以地苦胆、鹅不食草为臣药，可消肿利尿、通窍止痛，君臣配伍，增强主药疗效，其余中药组分为佐使药，其中鲜猕猴桃根可清热解毒，活血消肿，鲜半枝莲和干半枝莲用于疔疮肿毒、瘰疬、癌肿，还有咽喉的肿痛，白英可清热利湿、解毒消肿，细辛可散寒祛风、镇静、镇痛，辛荑花可散风寒、通鼻窍，深绿卷柏可活血通经，山豆根可清热解毒、消肿止痛，半边莲可利尿消肿、镇静降温，鸭跖草可清热泻火、解毒消肿、凉血止血，苍耳子可散寒、止痛、祛湿，苍术可健脾、燥湿、明目，白芷可祛风湿，活血排脓，生肌止痛，鱼腥草可清热解毒、利尿通淋、消炎，荜茇可温中散寒、下气止痛，薄荷可发汗解热、疏肝理气、利咽止痛、止痒，淡豆豉可解表、除烦、宣郁、解毒，防风可祛风解表、抗菌、止痒，升麻可清热解毒、发表透疹、升阳举陷，金荞麦可清热解毒、活血化瘀、祛痰利咽，对于过敏性鼻炎治标则祛邪止涕通窍，治本则益气补肺，而慢性鼻炎中发病机制中有肺气虚弱，邪滞鼻窍而致气化功能不健，则主治润肺，不仅同时可以治疗过敏性鼻炎和慢性鼻炎，还能延长疗效时间，此外在治疗鼻窦炎上也颇有成效。
具体实施方式
为了更好地理解本发明，下面结合实施例对本发明的实施方案进行详细描述，但是本领域技术人员将会理解，下列实施例仅用于说明本发明，而不应视为限制本发明的范围。
实施例1：
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，包括以下重量份数的组分：鲜猕猴桃根75份、鲜半枝莲50份、干半枝莲30份、白英30份、细辛3份、辛荑花10份、深绿卷柏15份、山豆根10份、白花蛇舌草15份、半边莲15份、鸭跖草15份、苍耳子10份、苍术10份、白芷10份、鹅不食草15份、鱼腥草15份、荜茇10份、甘草5份、荆芥10份、薄荷15份、淡豆豉15份、防风8份、升麻10份、金银花15份、蒲公英15份、紫花地丁15份、金荞麦15份、野菊花10份、地苦胆5份、瓜子金10份。
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，包括以下步骤：
A.按重量份数计，将上述中药材成分各自放入粉粹机中粉碎成粗粉，粒径在30-50目，再放入超微粉碎设备中继续进行粉碎得到细粉，粒径在250目以上；
B.将步骤A得到的各草药细粉混合，放入高粱酒中搅拌均匀，高粱酒与总中药粉末重量比为7:1，高粱酒度数为40°，静置，时间为5d之后再放入活性炭，10h后将活性炭取出，剩余的液体即得到的中药组合物。
实施例2：
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，包括以下重量份数的组分：鲜猕猴桃根50份、鲜半枝莲20份、干半枝莲15份、白英20份、细辛8份、辛荑花15份、深绿卷柏20份、山豆根15份、白花蛇舌草10份、半边莲19份、鸭跖草30份、苍耳子20份、苍术20份、白芷20份、鹅不食草10份、鱼腥草10份、荜茇20份、甘草10份、荆芥25份、薄荷30份、淡豆豉20份、防风5份、升麻20份、金银花10份、蒲公英10份、紫花地丁10份、金荞麦25份、野菊花20份、地苦胆10份、瓜子金20份。
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，包括以下步骤：
A.按重量份数计，将上述中药材成分各自放入粉粹机中粉碎成粗粉，粒径在60-80目，再放入超微粉碎设备中继续进行粉碎得到细粉，粒径在250目以上；
B.将步骤A得到的各草药细粉混合，放入高粱酒中搅拌均匀，高粱酒与总中药粉末重量比为10:1，高粱酒度数为50°，静置，时间为3d之后再放入活性炭12h后将活性炭取出，剩余的液体即得到的中药组合物。
实施例3：
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，包括以下重量份数的组分：鲜猕猴桃根30份、鲜半枝莲35份、干半枝莲20份、白英15份、细辛5份、辛荑花13份、深绿卷柏18份、山豆根15份、白花蛇舌草12份、半边莲20份、鸭跖草25份、苍耳子15份、苍术15份、白芷15份、鹅不食草20份、鱼腥草13份、荜茇15份、甘草8份、荆芥20份、薄荷20份、淡豆豉10份、防风20份、升麻15份、金银花13份、蒲公英12份、紫花地丁12份、金荞麦20份、野菊花15份、地苦胆7份、瓜子金15份。
一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，包括以下步骤：
A.按重量份数计，将上述中药材成分各自放入粉粹机中粉碎成粗粉，粒径在40-60目，再放入超微粉碎设备中继续进行粉碎得到细粉，粒径在250目以上；
B.将步骤A得到的各草药细粉混合，放入高粱酒中搅拌均匀，高粱酒与总中药粉末重量比为8:1，高粱酒度数为45°，静置，时间为4d之后再放入活性炭，11h后将活性炭取出，剩余的液体即得到的中药组合物。
对比例1：
对比例1与实施例1的区别在于，中药配方组分中省略野菊花、金银花和瓜子金，其他技术内容和实施例1相同。
对比例2：
对比例2与实施例1的区别在于，将中药配方中的金银花、野菊花、紫花地丁、蒲公英替换成银花藤叶，白花蛇舌草替换成水线草，瓜子金替换成冬凌草，其他技术内容和实施例1相同。
典型病例
病例一：刘某，男，患有慢性鼻窦炎，在一次急性化脓性鼻窦炎治疗后，经常伴有轻重不一的鼻塞，嗅觉不灵敏，擦了实施例1制作的中药组合物5天后，症状明显得到改善，嗅觉变好了，平时闻不到的味道能闻到了，鼻塞也有好转，程度较轻，没有脓涕流出，其疗效持续2年没有复发。
病例二：龚某，女，患有过敏性鼻炎，一到换季季节就出现打喷嚏频繁，鼻塞，流清鼻涕，使用了实施例1制作的中药组合物10天，鼻子通顺了，喷嚏不打了，偶有清鼻涕，不频繁，其治疗效果持续3年没有复发。
病例三：李某，女，患有慢性鼻炎，还伴有过敏性鼻炎，每当周围环境变换，恶化，就会出现打喷嚏、鼻塞，遇到感冒时，总有脓剃流出，且日久不好，使用了实施例制作得到的中药组合物半个月，鼻塞好了，不大喷嚏了，鼻子呼吸顺畅，脓涕转为清涕，且只是偶尔有清涕流出，量也不多，治疗后，在3-5年内因客观因素慢性鼻炎和过敏性鼻炎犯了，但症状都很轻，只是正常鼻子不舒服，最多轻度鼻塞，打喷嚏频率大大减少。
病例四：黄某，男，患有急性鼻窦炎，鼻塞，患侧有大量黏液脓性或脓性鼻涕，出现嗅觉减退或缺失，鼻出血，伴有头疼，使用了对比例1制作得到中药组合物10天，脓涕减少，但是鼻塞还有，只是程度减轻，嗅觉没有完全恢复，鼻出血没有了，头疼好转，在半年后复发，症状依然如故，并没有减轻。
病例五：王某，男，患有过敏性鼻炎，对一些花粉，柳絮，杨绵，灰尘等产生过敏反应，症状为鼻子痒，连打喷嚏、流清涕，鼻塞，使用了对比例2制作得到中药组合物半个月，鼻塞症状转轻，打喷嚏频率减少，偶尔有清涕流出，但是在1年后复发，症状出现频率并没有减少。
上述对实施例的描述是为了便于该技术领域的普通技术人员理解和使用本发明。熟悉本领域的技术人员可以容易地对这些实施例做出各种修改，并把在此说明的一般原理应用到其他实施例中，而不必经过创造性的劳动。因此，本发明不限于上述实施例。本领域技术人员根据本发明的原理，不脱离本发明的范畴所做出的改进和修改都应该在本发明的保护范围之内。
Claims (8)
1.一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，其特征在于，包括以下重量份数的组分：鲜猕猴桃根30-75份、鲜半枝莲20-50份、干半枝莲15-30份、白英15-30份、细辛3-8份、辛荑花10-15份、深绿卷柏15-20份、山豆根10-20份、白花蛇舌草10-15份、半边莲15-20份、鸭跖草15-30份、苍耳子10-20份、苍术10-20份、白芷10-20份、鹅不食草10-20份、鱼腥草10-15份、荜茇10-20份、甘草5-10份、荆芥10-25份、薄荷15-30份、淡豆豉10-20份、防风5-20份、升麻10-20份、金银花10-15份、蒲公英10-15份、紫花地丁10-15份、金荞麦15-25份、野菊花10-20份、地苦胆5-10份、瓜子金10-20份。
2.根据权利要求1所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，其特征在于，包括以下重量份数的组分：鲜猕猴桃根50-75份、鲜半枝莲35-50份、干半枝莲20-30份、白英20-30份、细辛3-5份、辛荑花10-13份、深绿卷柏18-20份、山豆根10-15份、白花蛇舌草12-15份、半边莲15-19份、鸭跖草15-25份、苍耳子10-15份、苍术10-15份、白芷10-15份、鹅不食草15-20份、鱼腥草13-15份、荜茇10-15份、甘草5-8份、荆芥10-20份、薄荷15-20份、淡豆豉15-20份、防风5-10份、升麻10-15份、金银花13-15份、蒲公英12-15份、紫花地丁12-15份、金荞麦15-20份、野菊花10-15份、地苦胆5-7份、瓜子金10-15份。
3.根据权利要求1所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物，其特征在于，包括以下重量份数的组分：鲜猕猴桃根75份、鲜半枝莲50份、干半枝莲30份、白英30份、细辛3份、辛荑花10份、深绿卷柏15份、山豆根10份、白花蛇舌草15份、半边莲15份、鸭跖草15份、苍耳子10份、苍术10份、白芷10份、鹅不食草15份、鱼腥草15份、荜茇10份、甘草5份、荆芥10份、薄荷15份、淡豆豉15份、防风8份、升麻10份、金银花15份、蒲公英15份、紫花地丁15份、金荞麦15份、野菊花10份、地苦胆5份、瓜子金10份。
4.根据权利要求1-3任意所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，其特征在于，包括以下步骤：
A.按重量份数计，将上述中药材成分各自放入粉粹机中粉碎成粗粉，再放入超微粉碎设备中继续进行粉碎得到细粉；
B.将步骤A得到的各草药细粉混合，放入高粱酒中搅拌均匀，静置，之后再放入活性炭，10-12h后将活性炭取出，剩余的液体即得到的中药组合物。
5.根据权利要求4所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，其特征在于，所述步骤A中粗粉粒径在30-80目，细粉粒径在250目以上。
6.根据权利要求4所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，其特征在于，所述步骤B中高粱酒与总中药粉末重量比为7-10:1。
7.根据权利要求4所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，其特征在于，所述步骤B中高粱酒度数为40-50°。
8.根据权利要求4所述的一种治疗过敏性鼻炎与慢性鼻炎的中药组合物的制作方法，其特征在于，所述步骤B中静置时间为3-5d。
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