CN114404494A - 一种化瘀止痛的外用药剂及其制备方法 - Google Patents
一种化瘀止痛的外用药剂及其制备方法 Download PDFInfo
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- CN114404494A CN114404494A CN202210152864.XA CN202210152864A CN114404494A CN 114404494 A CN114404494 A CN 114404494A CN 202210152864 A CN202210152864 A CN 202210152864A CN 114404494 A CN114404494 A CN 114404494A
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- parts
- blood stasis
- relieving pain
- removing blood
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Abstract
本发明提出了一种化瘀止痛的外用药剂及其制备方法,涉及中药技术领域。一种化瘀止痛的外用药剂,包括如下原料:伸筋草、透骨草、肿节风、三七、骨碎补、生川乌、生草乌、雪上一枝蒿、白鲜皮、两面针、威灵仙、麻黄、桂枝、鹿衔草、寻骨风、冰片、樟脑和薄荷脑。本发明以诸多药物相互协同作用,这样能够全方配伍,相得益彰,共同起到化瘀止痛之效,进而能够快速治疗瘀肿疼痛证。
Description
技术领域
本发明涉及中药技术领域,具体而言,涉及一种化瘀止痛的外用药剂及其制备方法。
背景技术
跌打损伤、风湿关节炎和股骨头坏死等疾病是由于长时间的关节、筋骨处气血不通,经络受阻,关节、筋骨失荣,或者急、慢性炎症等引起的机体肿胀或疼痛。使得患者关节痛、红肿、炎症,甚至活动受阻或功能受限,轻者疼痛影响正常的生活和睡眠,严重者甚至生活不能自理,给患者带来痛苦,同时也给家人增加了负担。
活血化瘀的中药应用历史悠久,临床应用十分广泛。它不仅能减轻和消除患者的痛苦而且能在一定程度上消除疼痛病,因标本兼治提高病愈率,特别对某些重度顽固性疼痛疗效显著。用外用药来达到镇痛消肿、活血化瘀和通络除痹的目的是我国自古以来传统的中医治疗方法。
常用的药剂有风湿贴和伤湿止痛膏等,但是这些药剂具有治疗时间长的缺点,常常需要长时间使用,且效果较差。
发明内容
本发明的目的在于提供一种化瘀止痛的外用药剂,此外用药剂具有见效快和效果好的优点。
本发明的另一目的在于提供一种化瘀止痛的外用药剂的制备方法,以获得此化瘀止痛的外用药剂。
本发明解决其技术问题是采用以下技术方案来实现的。
一方面,本申请实施例提供一种化瘀止痛的外用药剂,包括如下原料:伸筋草、透骨草、肿节风、三七、骨碎补、生川乌、生草乌、雪上一枝蒿、白鲜皮、两面针、威灵仙、麻黄、桂枝、鹿衔草、寻骨风、冰片、樟脑和薄荷脑。
另一方面,本申请实施例提供一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
将除冰片、樟脑和薄荷脑外的原料混合,并破碎,得到混合粉;
向混合粉中加入乙醇,浸泡后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
向混合液1中加入甘油,搅拌均匀,得到混合液2;
向混合液2中加入月桂氮酮,搅拌均匀,得到化瘀止痛的外用药剂成品。
本发明人认为瘀肿疼痛证多是由于跌打损伤或风寒湿痹引起的。对于跌打损伤,这是由于皮肤碰撞致使经络有死血,淤血阻滞,导致患处肿胀疼痛;风寒湿痹为人体内风寒湿三气夹杂的表现,湿热伤阴,又以湿热为主,致使经脉被病邪痹阻,使其沉涩,表现出的症状为肌肉、筋骨或关节酸痛、麻木。红肿疼痛。治疗均需要舒筋通脉,滋阴润络,活血强筋,祛风祛邪,而后能够到化瘀止痛的效果。
相对于现有技术,本发明的实施例至少具有如下优点或有益效果:
本发明人考虑到瘀肿疼痛证首要是因为经络闭塞,使得淤血阻滞,首先需要通经活络,以伸筋草、肿节风、两面针、桂枝、鹿衔草、生川乌、生草乌和寻骨风配伍,起到温养筋骨和疏络活筋之效;而血瘀多是由于寒凝、气滞和外伤造成的,在通经活络之后,能够便于气机通畅,但还需要行气活血,以两面针和肿节风起到行气活血之效;兼之风寒湿痹也会致使血瘀和红肿疼痛,以伸筋草、透骨草、生川乌、生草乌、雪上一枝蒿、白鲜皮、威灵仙、鹿衔草、薄荷脑、冰片和樟脑共用,起到祛湿清热之效;再有肾中元阴为诸阴之本,需要以肾为本,养肾生阴,濡养人体,以骨碎补起到补肾强身之效;而为了促进患处消肿,还以透骨草、骨碎补、生川乌、雪上一枝蒿、寻骨风、三七、两面针和麻黄起到消肿止痛之效。可以看出,该外用药剂并不是单独使用一类药物起到一个作用,而是诸多药物相互协同作用,这样能够全方配伍,相得益彰,共同起到化瘀止痛之效,进而能够快速治疗瘀肿疼痛证。
本发明通过将其破碎,再加入乙醇中浸渍,能够提取出各个药物中的有益成分,使得其药效渗透到乙醇中,而乙醇挥发性好,将其涂在肌肤上,能够保证仅仅有效用部分留存在皮肤上,进而渗透进皮肤起效;在最后加入冰片、樟脑和薄荷脑,除了本身的药效外,还能够提升食用感,舒适度高;在加入甘油,能够保证对皮肤起到保湿作用,防止乙醇带走身体表面的水份;而月桂氮酮的使用,能够促进各个效用物质渗透到皮肤,加速药效发挥作用。
具体实施方式
为使本发明实施例的目的、技术方案和优点更加清楚,下面将对本发明实施例中的技术方案进行清楚、完整地描述。实施例中未注明具体条件者,按照常规条件或制造商建议的条件进行。所用试剂或仪器未注明生产厂商者,均为可以通过市售购买获得的常规产品。
需要说明的是,在不冲突的情况下,本申请中的实施例及实施例中的特征可以相互组合。下面将参考具体实施例来详细说明本发明。
伸筋草:味微苦、辛,性温。归肝、脾、肾经。有祛风除湿和舒筋活络之效。用于关节酸痛,屈伸不利。
透骨草:味辛、苦,性温。有小毒。归肝、肾经。有祛风除湿和解毒止痛之效。用于风湿关节痛;外用治疮疡肿毒。
肿节风:味苦、辛,性平。归心、肝经。有清热凉血、活血消斑和祛风通络之效。用于血热紫斑、紫癜、风湿痹痛和跌打损伤。
三七:味甘、微苦,性温。归肝、胃经。有散瘀止血和消肿定痛之效。用于咯血、吐血、衄血、便血、崩漏、外伤出血、胸腹剌痛和跌扑肿痛。
骨碎补:味苦,性温。归肾、肝经。有补肾强骨和续伤止痛之效。用于肾虚腰痛、耳鸣耳聋、牙齿松动、跌扑闪挫、筋骨折伤;外治斑秃和白癜风。
生川乌:味辛、苦,性热。有大毒。归心、肝、肾、脾经。有祛风除湿和温经止痛之效。用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛,麻醉止痛。
生草乌:味辛、苦,性热。有大毒。归心、肝、肾、脾经。有祛风除湿和温经止痛之效。用于风寒湿痹,关节疼痛,心腹冷痛,寒疝作痛,麻醉止痛。
雪上一枝蒿:味苦、麻,性温。有大毒。有消炎止痛和祛风除湿之效。治跌打损伤,骨折,风湿骨痛,牙痛,疮疡肿毒,毒蛇咬伤。
白鲜皮:味苦,性寒。归脾、胃、膀胱经。有清热燥湿和祛风解毒之效。用于湿热疮毒,黄水淋漓,湿疹,风疹,疥癣疮癞,风湿热痹,黄疸尿赤。
两面针:味苦、辛,性平。有小毒。归肝、胃经。有行气止痛、活血化瘀和祛风通络之效。用于气滞血瘀引起的跌打损伤、风湿痹痛、胃痛、牙痛,毒蛇咬伤;外治汤火烫伤。
威灵仙:味辛、微苦,性寒。有祛风除湿和清热解毒之效。主感冒风热,咽喉肿痛,腮腺炎,风湿痹痛,虫蛇所伤。
麻黄:味辛、微苦,性温。归肺、膀胱经。有发汗散寒、宣肺平喘和利水消肿之效。用于风寒感冒,胸闷喘咳,风水浮肿;支气管哮喘。
桂枝:味辛、甘,性温。归心、肺、膀胱经。有发汗解肌、温通经脉、助阳化气和平冲降气之效。用于风寒感冒,脘腹冷痛,血寒经闭,关节痹痛,痰饮,水肿,心悸,奔豚。
鹿衔草:味甘、苦,性温。归肝、肾经。有祛风湿、强筋骨和止血之效。用于风湿痹痛,腰膝无力,月经过多,久咳劳嗽。
寻骨风:味辛、苦,性平。归肝经。有祛风通络和止痛之效。用于风湿痹痛,胃痛,睪丸肿痛,跌打伤痛等症。
冰片:味辛、苦,性微寒。归心、脾、肺经。有开窍醒神和清热止痛之效。用于热病神昏,痉厥,中风痰厥,气郁暴厥,中恶昏迷,目赤,口疮,咽喉肿痛,耳道流脓。
樟脑:味辛,性温。有通窍辟秽、温中止痛和利湿杀虫之效。用于寒湿吐泻,胃腹疼痛;外用治疥、癣、龋齿作痛。
薄荷脑:味辛,性凉。有疏风和清热之效。主风热感冒,头痛,目赤,咽喉肿痛,齿痛,皮肤瘙痒。
本发明提供一种化瘀止痛的外用药剂,包括如下原料:伸筋草、透骨草、肿节风、三七、骨碎补、生川乌、雪上一枝蒿、白鲜皮、两面针、威灵仙、麻黄、桂枝、鹿衔草、寻骨风、冰片、樟脑和薄荷脑。本发明是发明人经过多年研究,精选数味中药药材,合理配伍,能够达到对人体无毒副作用,且有效起到消肿止痛、祛风除湿、活血强筋、疏经通络的作用,表现出极佳的化瘀止痛之效。本发明人考虑到瘀肿疼痛证首要是因为经络闭塞,使得淤血阻滞,首先需要通经活络,以伸筋草、肿节风、两面针、桂枝、鹿衔草、生川乌、生草乌和寻骨风配伍,起到温养筋骨和疏络活筋之效;而血瘀多是由于寒凝、气滞和外伤造成的,在通经活络之后,能够便于气机通畅,但还需要行气活血,以两面针和肿节风起到行气活血之效;兼之风寒湿痹也会致使血瘀和红肿疼痛,以伸筋草、透骨草、生川乌、生草乌、雪上一枝蒿、白鲜皮、威灵仙、鹿衔草、薄荷脑、冰片和樟脑共用,起到祛湿清热之效;再有肾中元阴为诸阴之本,需要以肾为本,养肾生阴,濡养人体,以骨碎补起到补肾强身之效;而为了促进患处消肿,还以透骨草、骨碎补、生川乌、雪上一枝蒿、寻骨风、三七、两面针和麻黄起到消肿止痛之效。可以看出,该外用药剂并不是单独使用一类药物起到一个作用,而是诸多药物相互协同作用,这样能够全方配伍,相得益彰,共同起到化瘀止痛之效,进而能够快速治疗瘀肿疼痛证。
在本发明的一些实施例中,上述按重量份计,所述外用药剂包括如下原料:伸筋草50-150份、透骨草50-150份、肿节风50-150份、三七50-150份、骨碎补80-120份、生川乌50-150份、生草乌50-150份、雪上一枝蒿70-160份、白鲜皮50-150份、两面针50-150份、威灵仙80-120份、麻黄50-150份、桂枝50-150份、鹿衔草80-120份、寻骨风50-150份、冰片5-15份、樟脑5-15份和薄荷脑5-15份。
在本发明的一些实施例中,上述外用药剂包括如下原料:伸筋草100份、透骨草100份、肿节风100份、三七100份、骨碎补100份、生川乌100份、生草乌100份、雪上一枝蒿100份、白鲜皮100份、两面针100份、威灵仙100份、麻黄100份、桂枝100份、鹿衔草100份、寻骨风100份、冰片10份、樟脑10份和薄荷脑10份。
在本发明的一些实施例中,上述外用药剂包括如下原料:伸筋草80份、透骨草120份、肿节风120份、三七80份、骨碎补130份、生川乌120份、生草乌120份、雪上一枝蒿80份、白鲜皮120份、两面针120份、威灵仙120份、麻黄120份、桂枝120份、鹿衔草80份、寻骨风70份、冰片8份、樟脑12份和薄荷脑10份。
本发明还提供一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
将除冰片、樟脑和薄荷脑外的原料混合,并破碎,得到混合粉;
向混合粉中加入乙醇,浸泡后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
向混合液1中加入甘油,搅拌均匀,得到混合液2;
向混合液2中加入月桂氮酮,搅拌均匀,得到化瘀止痛的外用药剂成品。
在本发明的一些实施例中,上述混合粉尺寸为50-150目。充分的粉碎,能够使得药物被乙醇浸提,保证其药效挥发出来。
在本发明的一些实施例中,上述乙醇与混合粉的重量比为(18-23):7,所述乙醇体积浓度为50-70%。
在本发明的一些实施例中,上述浸泡时间为20-30天。
在本发明的一些实施例中,上述甘油与混合液1的重量比为(3-8):100。
在本发明的一些实施例中,上述月桂氮酮与混合液2的重量比为(1-3):100。
在本发明的一些实施例中,上述冰片、樟脑和薄荷脑被破碎为粉末。
以下结合实施例对本发明的特征和性能作进一步的详细描述。
实施例1
一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
原料:伸筋草20g、透骨草100g、肿节风200g、三七200g、骨碎补100g、生川乌50g、生草乌50g、雪上一枝蒿50g、白鲜皮40g、两面针40g、威灵仙70g、麻黄40g、桂枝100g、鹿衔草70g、寻骨风80g、冰片10g、樟脑10g和薄荷脑10g。
将除冰片、樟脑和薄荷脑外的原料混合,并破碎成50目的混合粉1;
按照18:7的重量比向混合粉1中加入体积浓度为50%的乙醇,浸泡20天后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
按照3:100的重量比向混合液1中加入甘油,搅拌均匀,得到混合液2;
按照1:100的重量比将月桂氮酮加入混合液2中,搅拌均匀,得到化瘀止痛的外用药剂成品。
实施例2
一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
原料:伸筋草50g、透骨草50g、肿节风50g、三七50g、骨碎补80g、生川乌50g、生草乌50g、雪上一枝蒿70g、白鲜皮50g、两面针50g、威灵仙80g、麻黄50g、桂枝50g、鹿衔草80g、寻骨风50g、冰片5g、樟脑5g和薄荷脑5g。
将除冰片、樟脑和薄荷脑外的原料混合,并破碎成50目的混合粉1;
按照18:7的重量比向混合粉1中加入体积浓度为50%的乙醇,浸泡20天后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
按照3:100的重量比向混合液1中加入甘油,搅拌均匀,得到混合液2;
按照1:100的重量比将月桂氮酮加入混合液2中,搅拌均匀,得到化瘀止痛的外用药剂成品。
实施例3
一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
原料:伸筋草100g、透骨草100g、肿节风100g、三七100g、骨碎补100g、生川乌100g、生草乌100g、雪上一枝蒿100g、白鲜皮100g、两面针100g、威灵仙100g、麻黄100g、桂枝100g、鹿衔草100g、寻骨风100g、冰片10g、樟脑10g和薄荷脑10g。
将除冰片、樟脑和薄荷脑外的原料混合,并破碎成100目的混合粉1;
按照20:7的重量比向混合粉1中加入体积浓度为60%的乙醇,浸泡25天后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
按照5:100的重量比向混合液1中加入甘油,搅拌均匀,得到混合液2;
按照2:100的重量比将月桂氮酮加入混合液2中,搅拌均匀,得到化瘀止痛的外用药剂成品。
实施例4
一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
原料:伸筋草80g、透骨草120g、肿节风120g、三七80g、骨碎补130g、生川乌120g、生草乌120g、雪上一枝蒿80g、白鲜皮120g、两面针120g、威灵仙120g、麻黄120g、桂枝120g、鹿衔草80g、寻骨风70g、冰片8g、樟脑12g和薄荷脑10g。
将除冰片、樟脑和薄荷脑外的原料混合,并破碎成100目的混合粉1;
按照21:7的重量比向混合粉1中加入体积浓度为65%的乙醇,浸泡25天后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
按照6:100的重量比向混合液1中加入甘油,搅拌均匀,得到混合液2;
按照2:100的重量比将月桂氮酮加入混合液2中,搅拌均匀,得到化瘀止痛的外用药剂成品。
实施例5
一种化瘀止痛的外用药剂的制备方法,包括如下步骤:
原料:伸筋草150g、透骨草150g、肿节风150g、三七150g、骨碎补120g、生川乌150g、生草乌150g、雪上一枝蒿160g、白鲜皮150g、两面针150g、威灵仙120g、麻黄150g、桂枝150g、鹿衔草120g、寻骨风150g、冰片15g、樟脑15g和薄荷脑15g。
将除冰片、樟脑和薄荷脑外的原料混合,并破碎成150目的混合粉1;
按照23:7的重量比向混合粉1中加入体积浓度为70%的乙醇,浸泡30天后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
按照8:100的重量比向混合液1中加入甘油,搅拌均匀,得到混合液2;
按照3:100的重量比将月桂氮酮加入混合液2中,搅拌均匀,得到化瘀止痛的外用药剂成品。
实验例
(一)、选择体重在200±20g的SD大鼠60只,适应性饲养3天,将SD大鼠随机均分为6组,6组SD大鼠均用钝器(质量200g)撞击大鼠后腿外侧,连续10次,造成局部软组织挫伤,1-5组为实验组,分别用实施例1-5制备的外用药剂治疗,6组用市面上购买的红花油进行治疗。治疗均为将药剂涂覆于伤处,每天早晚2次用药,分别在3天和6天后对大鼠进行评价。实验期间均处于同一饲养条件下。结果如表1所示。
评价标准:
恢复良好:伤处无瘀血、无肿胀且皮肤色泽正常。
恢复较好:存在少量点状瘀血、伤处稍有肿胀或皮肤色泽较为暗红色。
恢复较差:伤处多处瘀血或瘀血面积较大、伤处明显肿胀且伤处皮肤为深紫红色。
表1
分析对比表1,可以看出,相对于6组而言,1-5组的大鼠的恢复更好,这说明本申请制备的外用药剂对于大鼠的治疗更有效,对比1-5组,可以看出,4组的治疗效果最佳,这说明对于跌打损伤造成的瘀血红肿,实施例4制备的外用药剂的治疗效果最佳。
(二)、典型案例:
1、赵xx,男、54岁,双膝关节疼痛伴随红肿,且喜暖怕冷,遇到寒冷和阴雨天症状更严重,用本发明实施例3制备的外用药剂每日早晚在双膝关节使用,使用时伴以揉搓,使患处发热,持续3天,以后症状明显好转,持续15天后,双膝关节基本恢复。
2、黄xx,女、49岁,双手指关节红肿、疼痛,且关节僵硬,不易弯曲,用本发明实施例4制备的外用药剂每日早晚在指关节使用,使用时伴以揉搓,使患处发热,持续3天,以后症状明显好转,持续10天后,指关节基本恢复。
综上所述,本发明人考虑到瘀肿疼痛证首要是因为经络闭塞,使得淤血阻滞,首先需要通经活络,以伸筋草、肿节风、两面针、桂枝、鹿衔草、生川乌、生草乌和寻骨风配伍,起到温养筋骨和疏络活筋之效;而血瘀多是由于寒凝、气滞和外伤造成的,在通经活络之后,能够便于气机通畅,但还需要行气活血,以两面针和肿节风起到行气活血之效;兼之风寒湿痹也会致使血瘀和红肿疼痛,以伸筋草、透骨草、生川乌、生草乌、雪上一枝蒿、白鲜皮、威灵仙、鹿衔草、薄荷脑、冰片和樟脑共用,起到祛湿清热之效;再有肾中元阴为诸阴之本,需要以肾为本,养肾生阴,濡养人体,以骨碎补起到补肾强身之效;而为了促进患处消肿,还以透骨草、骨碎补、生川乌、雪上一枝蒿、寻骨风、三七、两面针和麻黄起到消肿止痛之效。可以看出,该外用药剂并不是单独使用一类药物起到一个作用,而是诸多药物相互协同作用,这样能够全方配伍,相得益彰,共同起到化瘀止痛之效,进而能够快速治疗瘀肿疼痛证。
本发明通过将其破碎,再加入乙醇中浸渍,能够提取出各个药物中的有益成分,使得其药效渗透到乙醇中,而乙醇挥发性好,将其涂在肌肤上,能够保证仅仅有效用部分留存在皮肤上,进而渗透进皮肤起效;在最后加入冰片、樟脑和薄荷脑,除了本身的药效外,还能够提升食用感,舒适度高;在加入甘油,能够保证对皮肤起到保湿作用,防止乙醇带走身体表面的水份;而月桂氮酮的使用,能够促进各个效用物质渗透到皮肤,加速药效发挥作用。
以上所描述的实施例是本发明一部分实施例,而不是全部的实施例。本发明的实施例的详细描述并非旨在限制要求保护的本发明的范围,而是仅仅表示本发明的选定实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
Claims (10)
1.一种化瘀止痛的外用药剂,其特征在于,包括如下原料:伸筋草、透骨草、肿节风、三七、骨碎补、生川乌、生草乌、雪上一枝蒿、白鲜皮、两面针、威灵仙、麻黄、桂枝、鹿衔草、寻骨风、冰片、樟脑和薄荷脑。
2.根据权利要求1所述的一种化瘀止痛的外用药剂,其特征在于,按重量份计,所述外用药剂包括如下原料:伸筋草50-150份、透骨草50-150份、肿节风50-150份、三七50-150份、骨碎补80-120份、生川乌50-150份、生草乌50-150份、雪上一枝蒿70-160份、白鲜皮50-150份、两面针50-150份、威灵仙80-120份、麻黄50-150份、桂枝50-150份、鹿衔草80-120份、寻骨风50-150份、冰片5-15份、樟脑5-15份和薄荷脑5-15份。
3.根据权利要求1所述的一种化瘀止痛的外用药剂,其特征在于,按重量份计,所述外用药剂包括如下原料:伸筋草100份、透骨草100份、肿节风100份、三七100份、骨碎补100份、生川乌100份、生草乌100份、雪上一枝蒿100份、白鲜皮100份、两面针100份、威灵仙100份、麻黄100份、桂枝100份、鹿衔草100份、寻骨风100份、冰片10份、樟脑10份和薄荷脑10份。
4.根据权利要求1所述的一种化瘀止痛的外用药剂,其特征在于,按重量份计,所述外用药剂包括如下原料:伸筋草80份、透骨草120份、肿节风120份、三七80份、骨碎补130份、生川乌120份、生草乌120份、雪上一枝蒿80份、白鲜皮120份、两面针120份、威灵仙120份、麻黄120份、桂枝120份、鹿衔草80份、寻骨风70份、冰片8份、樟脑12份和薄荷脑10份。
5.如权利要求1-4任意一项所述的一种化瘀止痛的外用药剂的制备方法,其特征在于,包括如下步骤:
将除冰片、樟脑和薄荷脑外的原料混合,并破碎,得到混合粉;
向混合粉中加入乙醇,浸泡后,过滤,收集滤液;
向滤液中加入冰片、樟脑和薄荷脑,搅拌均匀后,得到混合液1;
向混合液1中加入甘油,搅拌均匀,得到混合液2;
向混合液2中加入月桂氮酮,搅拌均匀,得到化瘀止痛的外用药剂成品。
6.根据权利要求5所述的一种化瘀止痛的外用药剂的制备方法,其特征在于,所述混合粉尺寸为50-150目。
7.根据权利要求5所述的一种化瘀止痛的外用药剂的制备方法,其特征在于,所述乙醇与混合粉的重量比为(18-23):7,所述乙醇体积浓度为50-70%。
8.根据权利要求5所述的一种化瘀止痛的外用药剂的制备方法,其特征在于,所述浸泡时间为20-30天。
9.根据权利要求5所述的一种化瘀止痛的外用药剂的制备方法,其特征在于,所述甘油与混合液1的重量比为(3-8):100。
10.根据权利要求5所述的一种化瘀止痛的外用药剂的制备方法,其特征在于,所述月桂氮酮与混合液2的重量比为(1-3):100。
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