CN114344386A - Traditional Chinese medicine composition for treating pruritus vulvae and application thereof - Google Patents
Traditional Chinese medicine composition for treating pruritus vulvae and application thereof Download PDFInfo
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- CN114344386A CN114344386A CN202210049641.0A CN202210049641A CN114344386A CN 114344386 A CN114344386 A CN 114344386A CN 202210049641 A CN202210049641 A CN 202210049641A CN 114344386 A CN114344386 A CN 114344386A
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- chinese medicine
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- pruritus vulvae
- treating pruritus
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- 239000003814 drug Substances 0.000 title claims abstract description 61
- 208000008350 Pruritus Vulvae Diseases 0.000 title claims abstract description 32
- 206010056530 Vulvovaginal pruritus Diseases 0.000 title claims abstract description 32
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- 239000002994 raw material Substances 0.000 claims abstract description 32
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract description 19
- 241000723346 Cinnamomum camphora Species 0.000 claims abstract description 19
- 229930008380 camphor Natural products 0.000 claims abstract description 19
- 229960000846 camphor Drugs 0.000 claims abstract description 19
- 206010004542 Bezoar Diseases 0.000 claims abstract description 14
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 13
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 13
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229940116229 borneol Drugs 0.000 claims abstract description 13
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 13
- 244000124209 Crocus sativus Species 0.000 claims abstract description 11
- 235000015655 Crocus sativus Nutrition 0.000 claims abstract description 11
- 244000035851 Chrysanthemum leucanthemum Species 0.000 claims abstract description 10
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 claims abstract description 10
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 40
- 239000002674 ointment Substances 0.000 claims description 29
- 239000000243 solution Substances 0.000 claims description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 24
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 23
- 238000003756 stirring Methods 0.000 claims description 18
- 235000013399 edible fruits Nutrition 0.000 claims description 16
- 239000011259 mixed solution Substances 0.000 claims description 14
- 239000000706 filtrate Substances 0.000 claims description 12
- 239000006228 supernatant Substances 0.000 claims description 12
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- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims description 8
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- 241000207929 Scutellaria Species 0.000 claims description 8
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- MFYSUUPKMDJYPF-UHFFFAOYSA-N 2-[(4-methyl-2-nitrophenyl)diazenyl]-3-oxo-n-phenylbutanamide Chemical compound C=1C=CC=CC=1NC(=O)C(C(=O)C)N=NC1=CC=C(C)C=C1[N+]([O-])=O MFYSUUPKMDJYPF-UHFFFAOYSA-N 0.000 claims description 7
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- 238000000034 method Methods 0.000 claims description 7
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- 238000001556 precipitation Methods 0.000 claims description 6
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- 230000001954 sterilising effect Effects 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims 2
- 235000011187 glycerol Nutrition 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 16
- 208000003251 Pruritus Diseases 0.000 abstract description 10
- 206010061218 Inflammation Diseases 0.000 abstract description 6
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- 230000002147 killing effect Effects 0.000 abstract description 3
- 238000001035 drying Methods 0.000 abstract description 2
- 230000002401 inhibitory effect Effects 0.000 abstract description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 8
- 201000010099 disease Diseases 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
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- 238000002360 preparation method Methods 0.000 description 5
- 244000045947 parasite Species 0.000 description 3
- 201000004624 Dermatitis Diseases 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 230000000670 limiting effect Effects 0.000 description 2
- 206010033675 panniculitis Diseases 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 235000013974 saffron Nutrition 0.000 description 2
- 239000004248 saffron Substances 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 210000004304 subcutaneous tissue Anatomy 0.000 description 2
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- 241000130781 Arnebia Species 0.000 description 1
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- 206010013700 Drug hypersensitivity Diseases 0.000 description 1
- 241000628997 Flos Species 0.000 description 1
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- 238000012986 modification Methods 0.000 description 1
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- 210000004400 mucous membrane Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 230000001314 paroxysmal effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
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- 239000003440 toxic substance Substances 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 210000003905 vulva Anatomy 0.000 description 1
- 229940126673 western medicines Drugs 0.000 description 1
Classifications
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a traditional Chinese medicine composition for treating pruritus vulvae, which is prepared from the following raw materials in parts by weight: 340 parts of fructus cnidii, 340 parts of fructus kochiae, 260 parts of periploca forrestii, 420 parts of radix sophorae flavescentis 380, 260 parts of scutellaria baicalensis 220, 200 parts of rheum officinale 160, 200 parts of lithospermum 160, 10-30 parts of saffron crocus, 200 parts of cortex meliae 160, 200 parts of wild chrysanthemum 160, 8-12 parts of artificial bezoar, 1-3 parts of camphor and 0.8-1.2 parts of borneol; the traditional Chinese medicine composition has reasonable monarch, minister, assistant and guide compatibility, achieves the effects of clearing heat and drying dampness, killing and inhibiting bacteria, relieving itching and eliminating inflammation under the combined action, and has the effective rate of treating patients with pruritus vulvae of more than 93 percent.
Description
Technical Field
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating pruritus vulvae and application thereof.
Background
Pruritus vulvae is a common gynecological disease and a symptom caused by various lesions of vulva, and the common causes are as follows: the pudendum pruritus is caused by pudendum skin allergy or skin inflammation caused by drug allergy or chemical stimulation; thirdly, vulvar pruritus is caused by the unsanitary pudendum, poor air permeability or bad stimulation caused by the carelessness of cleanness and poor clothing quality; the pruritus vulvae symptom is usually paroxysmal, is generally aggravated at night or when irritant food is eaten, brings serious influence to the work and life of a patient, the pruritus seriously influences the sleep of the patient, other diseases are caused, and great trouble is caused to the life of the patient;
at present, the western medicine treatment adopts anti-infection and other comprehensive therapies, and mostly adopts oral or external western medicines, which have certain side effects, frequently relapse of the disease and unsatisfactory treatment effect; therefore, the traditional Chinese medicine composition treats pruritus vulvae through a dialectical formula of the traditional Chinese medicine, has a good curative effect, is coated by adopting an ointment, greatly reduces the side effect of the medicine on a patient, and achieves the purpose of fundamentally treating diseases.
Disclosure of Invention
In order to overcome the technical problems, the invention aims to provide a traditional Chinese medicine composition for treating pruritus vulvae and application thereof.
In order to achieve the purpose, the invention adopts the technical scheme that:
a traditional Chinese medicine composition for treating pruritus vulvae is composed of the following raw materials in parts by weight:
340 parts of fructus cnidii, 340 parts of fructus kochiae, 260 parts of periploca forrestii, 420 parts of radix sophorae flavescentis 380, 260 parts of scutellaria baicalensis 220, 200 parts of rheum officinale 160, 200 parts of lithospermum 160, 10-30 parts of saffron crocus, 200 parts of cortex meliae 160, 200 parts of wild chrysanthemum 160, 8-12 parts of artificial bezoar, 1-3 parts of camphor and 0.8-1.2 parts of borneol;
preferably, the traditional Chinese medicine composition for treating pruritus vulvae is prepared from the following raw materials in parts by weight:
320 parts of common cnidium fruit, 320 parts of belvedere fruit, 240 parts of periploca forrestii schltr, 400 parts of lightyellow sophora root, 240 parts of baical skullcap root, 180 parts of rhubarb, 180 parts of lithospermum, 20 parts of saffron crocus, 180 parts of chinaberry bark, 180 parts of wild chrysanthemum flower, 10 parts of artificial bezoar, 2 parts of camphor and 1 part of borneol;
the invention also provides a traditional Chinese medicine ointment containing the traditional Chinese medicine composition for treating pruritus vulvae.
The preparation method of the traditional Chinese medicine ointment specifically comprises the following steps:
(1) boiling in water: decocting the raw material medicines in parts by weight with water for 3 times, wherein the water adding amount and the decocting time are respectively 10 times and 90 minutes; 8 times of the amount of the raw materials, and 60 minutes; 6 times of the amount of the raw materials, and 40 minutes; filtering, mixing filtrates, and concentrating the filtrate to obtain concentrated solution A;
(2) alcohol precipitation: adding ethanol into the concentrated solution A in the step (1), stirring to obtain a mixed solution, refrigerating the mixed solution for 24 hours, taking a supernatant, and recovering the ethanol in the supernatant to obtain a concentrated solution B;
(3) preparing an ointment: adding the artificial bezoar and the camphor in parts by weight into the concentrated solution B in the step (2), uniformly stirring, adding the glycerol, the carbomer and the purified water, fully stirring, sterilizing, filling and packaging to obtain the traditional Chinese medicine ointment.
Further, the relative density of the concentrated solution A in the step (1) is 1.06-1.14;
further, the relative density of the concentrated solution B in the step (2) is 1.10-1.15;
further, the content of ethanol in the mixed solution in the step (2) is 65 +/-2%;
further, the weight ratio of the glycerol to the carbomer in the step (2) is 37.5: 1.
The Chinese medicinal composition takes the common cnidium fruit, the belvedere fruit and the lightyellow sophora root as monarch medicaments, and the common cnidium fruit can eliminate dampness and expel wind, kill parasites and relieve itching, warm kidney and strengthen yang; the broom cypress fruit can clear heat, promote diuresis, dispel wind and relieve itching; the sophora flavescens can clear heat, promote diuresis, resist bacteria, diminish inflammation and expel parasites;
the traditional Chinese medicine composition takes the cortex meliae, the wild chrysanthemum and the periploca forrestii as ministerial medicines, and the cortex meliae can clear heat, dry dampness and kill insects; flos Chrysanthemi Indici has effects of dispelling pathogenic wind and heat, relieving swelling and removing toxic substance; caulis et folium Periplocae Forrestii can promote blood circulation and remove meridian obstruction; the three components act together to play the roles of clearing heat and drying dampness, and killing insects and detoxifying;
the invention takes the baical skullcap root, the rhubarb, the sinkiang arnebia root and the saffron as adjuvant drugs, and the baical skullcap root can clear heat and dry dampness; radix et rhizoma Rhei has effects in cooling blood, dispelling blood stasis, and stopping bleeding; the lithospermum has the effects of cooling blood, activating blood, detoxifying and promoting eruption; the saffron has the effects of promoting blood circulation to remove blood stasis, dispersing stagnation and relieving stasis and pain;
in the invention, camphor and borneol are used as guiding drugs; the camphor can relieve swelling and pain, kill parasites and relieve itching, the borneol can promote the absorption of the traditional Chinese medicine components through mucous membrane and subcutaneous tissues, and the camphor and the borneol can achieve the effects of relieving pain and harmonizing the medicines by the combination of the camphor, the borneol and the subcutaneous tissues;
the traditional Chinese medicine composition has the effects of clearing heat, eliminating dampness, killing and inhibiting bacteria, relieving itching and eliminating inflammation through the compatibility of monarch, minister, assistant and guide; is not only suitable for the diseases of recurrent pruritus vulvae, leukoplakia vulvae and the like, but also has ideal effect on treating the diseases of skin pruritus and the like caused by unknown reasons and inflammation.
The traditional Chinese medicine composition has the advantages of wide raw material medicine source, low cost, no side effect and high clinical application value;
Detailed Description
The technical solutions of the present invention will be described in detail with reference to specific examples, but those skilled in the art will understand that the following examples are only illustrative of the present invention and should not be construed as limiting the scope of the present invention.
Example 1
A traditional Chinese medicine composition for treating pruritus vulvae is composed of the following raw materials in parts by weight:
300 parts of common cnidium fruit, 300 parts of belvedere fruit, 220 parts of periploca forrestii schltr, 380 parts of lightyellow sophora root, 220 parts of baical skullcap root, 160 parts of rhubarb, 160 parts of lithospermum, 10 parts of saffron crocus, 160 parts of chinaberry bark, 160 parts of wild chrysanthemum flower, 8 parts of artificial bezoar, 1 part of camphor and 0.8 part of borneol;
the preparation method of the traditional Chinese medicine ointment containing the traditional Chinese medicine composition for treating pruritus vulvae specifically comprises the following steps:
(1) boiling in water: decocting the raw material medicines in parts by weight with water for 3 times, wherein the water adding amount and the decocting time are respectively 10 times and 90 minutes; 8 times of the amount of the raw materials, and 60 minutes; 6 times of the amount of the raw materials, and 40 minutes; filtering, mixing filtrates, and concentrating the filtrate to obtain concentrated solution A with relative density of 1.06-1.14;
(2) alcohol precipitation: adding ethanol into the concentrated solution A obtained in the step (1), stirring to obtain a mixed solution (wherein the ethanol content is 65 +/-2%), refrigerating the mixed solution for 24 hours, taking a supernatant, and recovering the ethanol in the supernatant to obtain a concentrated solution B with the relative density of 1.10-1.15;
(3) preparing an ointment: adding the artificial bezoar and the camphor in parts by weight into the concentrated solution B in the step (2), uniformly stirring, adding 300 parts of glycerol and 8 parts of carbomer, adding purified water, fully stirring, sterilizing, filling and packaging to obtain a traditional Chinese medicine ointment;
the raw material medicine is 50 g/part.
Example 2
A traditional Chinese medicine composition for treating pruritus vulvae is composed of the following raw materials in parts by weight:
320 parts of common cnidium fruit, 320 parts of belvedere fruit, 240 parts of periploca forrestii schltr, 400 parts of lightyellow sophora root, 240 parts of baical skullcap root, 180 parts of rhubarb, 180 parts of lithospermum, 20 parts of saffron crocus, 180 parts of chinaberry bark, 180 parts of wild chrysanthemum flower, 10 parts of artificial bezoar, 2 parts of camphor and 1 part of borneol;
the preparation method of the traditional Chinese medicine ointment containing the traditional Chinese medicine composition for treating pruritus vulvae specifically comprises the following steps:
(1) boiling in water: decocting the raw material medicines in parts by weight with water for 3 times, wherein the water adding amount and the decocting time are respectively 10 times and 90 minutes; 8 times of the amount of the raw materials, and 60 minutes; 6 times of the amount of the raw materials, and 40 minutes; filtering, mixing filtrates, and concentrating the filtrate to obtain concentrated solution A with relative density of 1.06-1.14;
(2) alcohol precipitation: adding ethanol into the concentrated solution A in the step (1), stirring to obtain a mixed solution (wherein the ethanol content is 65 +/-2%), refrigerating the mixed solution for 24 hours, taking a supernatant, and recovering the ethanol in the supernatant to obtain a concentrated solution B with the relative density of 1.10-1.15;
(3) preparing an ointment: adding the artificial bezoar and the camphor in parts by weight into the concentrated solution B in the step (2), uniformly stirring, adding 300 parts of glycerol and 8 parts of carbomer, adding purified water, fully stirring, sterilizing, filling and packaging to obtain a traditional Chinese medicine ointment;
the raw material medicine is 50 g/part.
Example 3
A traditional Chinese medicine composition for treating pruritus vulvae is composed of the following raw materials in parts by weight:
300 parts of common cnidium fruit, 300 parts of belvedere fruit, 220 parts of periploca forrestii schltr, 420 parts of lightyellow sophora root, 260 parts of baical skullcap root, 200 parts of rhubarb, 160 parts of lithospermum, 10 parts of saffron crocus, 200 parts of chinaberry bark, 160 parts of wild chrysanthemum flower, 8 parts of artificial bezoar, 3 parts of camphor and 0.8 part of borneol;
the preparation method of the traditional Chinese medicine ointment containing the traditional Chinese medicine composition for treating pruritus vulvae specifically comprises the following steps:
(1) boiling in water: decocting the raw material medicines in parts by weight with water for 3 times, wherein the water adding amount and the decocting time are respectively 10 times and 90 minutes; 8 times of the amount of the raw materials, and 60 minutes; 6 times of the amount of the raw materials, and 40 minutes; filtering, mixing filtrates, and concentrating the filtrate to obtain concentrated solution A with relative density of 1.06-1.14;
(2) alcohol precipitation: adding ethanol into the concentrated solution A in the step (1), stirring to obtain a mixed solution (wherein the ethanol content is 65 +/-2%), refrigerating the mixed solution for 24 hours, taking a supernatant, and recovering the ethanol in the supernatant to obtain a concentrated solution B with the relative density of 1.10-1.15;
(3) preparing an ointment: adding the artificial bezoar and the camphor in parts by weight into the concentrated solution B in the step (2), uniformly stirring, adding 300 parts of glycerol and 8 parts of carbomer, adding purified water, fully stirring, sterilizing, filling and packaging to obtain a traditional Chinese medicine ointment;
the raw material medicine is 50 g/part.
Example 4
A traditional Chinese medicine composition for treating pruritus vulvae is composed of the following raw materials in parts by weight:
340 parts of common cnidium fruit, 340 parts of belvedere fruit, 260 parts of periploca forrestii schltr, 420 parts of lightyellow sophora root, 260 parts of baical skullcap root, 200 parts of rhubarb, 200 parts of lithospermum, 30 parts of saffron crocus, 200 parts of chinaberry bark, 200 parts of wild chrysanthemum flower, 12 parts of calculus bovis factitius, 3 parts of camphor and 1.2 parts of borneol;
the preparation method of the traditional Chinese medicine ointment containing the traditional Chinese medicine composition for treating pruritus vulvae specifically comprises the following steps:
(1) boiling in water: decocting the raw material medicines in parts by weight with water for 3 times, wherein the water adding amount and the decocting time are respectively 10 times and 90 minutes; 8 times of the amount of the raw materials, and 60 minutes; 6 times of the amount of the raw materials, and 40 minutes; filtering, mixing filtrates, and concentrating the filtrate to obtain concentrated solution A with relative density of 1.06-1.14;
(2) alcohol precipitation: adding ethanol into the concentrated solution A in the step (1), stirring to obtain a mixed solution, refrigerating the mixed solution for 24 hours, taking a supernatant, and recovering the ethanol in the supernatant to obtain a concentrated solution B with the relative density of 1.10-1.15;
(3) preparing an ointment: adding the artificial bezoar and the camphor in parts by weight into the concentrated solution B in the step (2), uniformly stirring, adding 300 parts of glycerol and 8 parts of carbomer, adding purified water, fully stirring, sterilizing, filling and packaging to obtain a traditional Chinese medicine ointment;
the raw material medicine is 50 g/part.
Clinical data
The traditional Chinese medicine ointment prepared in the embodiment 2 is used for treating patients with pruritus vulvae, 44 cases of pruritus vulvae are selected, the age is 18-55 years, and the curative effect is clinically observed;
the usage method comprises the following steps: before sleeping at night, the ointment prepared in the embodiment 2 of the invention is dipped by a cotton swab and is smeared on an affected part once a day, and the dosage is suitable for uniformly covering the affected part; four treatment courses are provided, one treatment course is one week, and the treatment is continued for one month.
The therapeutic effect judgment standard is as follows:
(1) and (3) curing: the clinical symptoms of the patients all disappeared.
(2) The effect is shown: the clinical symptoms of the patients are obviously relieved.
(3) The method has the following advantages: the clinical symptoms of the patients are relieved.
(4) And (4) invalidation: the primary symptoms are not reduced or worsened by the treatment.
As a result:
| group of | Number of examples | Cure of disease | Show effect | Is effective | Invalidation | Cure rate | Total effective rate |
| Test group | 44 | 16 | 20 | 5 | 3 | 36.4％ | 93.2％ |
The traditional Chinese medicine composition has no adverse reaction;
after patients in the test group are cured, the patients are periodically revisited for one year, and the patients do not relapse within one year after being cured;
the traditional Chinese medicine ointment has the effective rate of treating the pruritus vulvae patients of more than 93 percent, has no toxic or side effect, and has no relapse after healing.
The ointment of the invention can improve pruritus and treat pudendum inflammation, and has wide application value in the aspect of treating gynecological inflammation diseases.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.
Claims (8)
1. A traditional Chinese medicine composition for treating pruritus vulvae is characterized by comprising the following raw materials in parts by weight: 340 parts of fructus cnidii, 340 parts of fructus kochiae, 260 parts of periploca forrestii, 420 parts of radix sophorae flavescentis 380, 260 parts of scutellaria baicalensis 220, 200 parts of rheum officinale 160, 200 parts of lithospermum 160, 10-30 parts of saffron crocus, 200 parts of cortex meliae 160, 200 parts of wild chrysanthemum 160, 8-12 parts of artificial bezoar, 1-3 parts of camphor and 0.8-1.2 parts of borneol.
2. The traditional Chinese medicine composition for treating pruritus vulvae of claim 1, which is prepared from the following raw materials in parts by weight: 320 parts of common cnidium fruit, 320 parts of belvedere fruit, 240 parts of periploca forrestii schltr, 400 parts of lightyellow sophora root, 240 parts of baical skullcap root, 180 parts of rhubarb, 180 parts of lithospermum, 20 parts of saffron crocus, 180 parts of chinaberry bark, 180 parts of wild chrysanthemum flower, 10 parts of artificial bezoar, 2 parts of camphor and 1 part of borneol.
3. A traditional Chinese medicine ointment for treating pruritus vulvae, which comprises the traditional Chinese medicine composition of claim 1 or 2.
4. A method for preparing a traditional Chinese medicine ointment for treating pruritus vulvae according to claim 3, which comprises the following steps:
(1) boiling in water: decocting the raw material medicines in parts by weight with water for 3 times, wherein the water adding amount and the decocting time are respectively 10 times and 90 minutes; 8 times of the amount of the raw materials, and 60 minutes; 6 times of the amount of the raw materials, and 40 minutes; filtering, mixing filtrates, and concentrating the filtrate to obtain concentrated solution A;
(2) alcohol precipitation: adding ethanol into the concentrated solution A in the step (1), stirring to obtain a mixed solution, refrigerating the mixed solution for 24 hours, taking a supernatant, and recovering the ethanol in the supernatant to obtain a concentrated solution B;
(3) preparing an ointment: adding the artificial bezoar and the camphor in parts by weight into the concentrated solution B in the step (2), uniformly stirring, adding the glycerol, the carbomer and the purified water, fully stirring, sterilizing, filling and packaging to obtain the traditional Chinese medicine ointment.
5. The method for preparing a Chinese medicinal ointment for treating pruritus vulvae of claim 4, wherein the relative density of the concentrate A in the step (1) is 1.06-1.14.
6. The method for preparing a Chinese medicinal ointment for treating pruritus vulvae of claim 4, wherein the relative density of the concentrate B in the step (2) is 1.10-1.15.
7. The method for preparing a Chinese medicinal ointment for treating pruritus vulvae of claim 4, wherein the content of ethanol in the mixed solution in the step (2) is 65 ± 2%.
8. The method for preparing a Chinese medicinal ointment for treating pruritus vulvae of claim 4, wherein the weight ratio of the glycerin to the carbomer in the step (2) is 37.5: 1.
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