CN114323882A - Slide glass making devices - Google Patents
Slide glass making devices Download PDFInfo
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- CN114323882A CN114323882A CN202111661113.2A CN202111661113A CN114323882A CN 114323882 A CN114323882 A CN 114323882A CN 202111661113 A CN202111661113 A CN 202111661113A CN 114323882 A CN114323882 A CN 114323882A
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Abstract
The invention provides a slide glass manufacturing device, which comprises a dye solution groove, a first dye solution groove and a second dye solution groove, wherein the first dye solution groove and the second dye solution groove are arranged side by side along a first direction and used for storing a first dye solution; the first dye groove and the second dye groove are respectively provided with a plurality of first basket bodies which are arranged along a second direction different from the first direction and can be inserted with slide inserting positions of a slide, and the slide inserting positions of each first basket body are communicated with the dye groove where the first basket body is located in a fluid mode. The glass slide making device with the structure can effectively reduce the volume of the whole dye solution tank on one hand, and on the other hand, the independent first basket bodies are arranged in the first dye solution tank and the second dye solution tank, so that when the first basket bodies need to be cleaned, the first basket bodies can be taken out and cleaned, and the glass slide making device is convenient for a user to maintain.
Description
Technical Field
The invention relates to the field of in vitro diagnosis, in particular to a glass slide manufacturing device for performing staining treatment on a glass slide.
Background
In the prior art, devices for staining glass slides include a plurality of devices, one of which is disc-shaped, a plurality of staining boxes are annularly arranged in an annular staining tank, and each glass slide needs one staining box, so that the structure is complex; the other type is in a linear shape, a plurality of dyeing positions are arranged in a straight line, different dyeing treatments are required to be carried out on the glass slide, so that the number of the dyeing positions required to be arranged is large, all the dyeing positions are arranged in a straight line, the structure is not compact enough, and the whole dyeing device occupies a large space.
Disclosure of Invention
The embodiment of the application provides a slide glass manufacturing device, and the purpose of reducing the size of the device can be achieved through the dyeing positions of the slide glass in reasonable layout.
The slide glass processing apparatus provided by the embodiment of the application includes:
the dye tank is provided with a first dye tank and a second dye tank, wherein the first dye tank is used for storing a first dye solution and the second dye tank is used for storing a second dye solution; wherein the content of the first and second substances,
the first dye groove and the second dye groove are both provided with a first basket body which is provided with a plurality of slide inserting positions which are arranged along a second direction different from the first direction and can be inserted with a slide,
the plurality of slide insertion sites of each first basket are in fluid communication with the dye bath in which the first basket is located.
Further, the method also comprises the following steps:
a fixed liquid tank which is arranged along a first direction side by side with the dye tank and is positioned at one side of the dye tank and used for storing fixed liquid,
the fixed liquid groove is internally provided with a second basket body which is provided with a plurality of slide inserting positions which are arranged along the second direction and can be inserted with a slide.
Further, the plurality of slide insertion sites of the second basket body include a first type slide insertion site capable of being in fluid communication with the fixed fluid bath and a second type slide insertion site fluidly isolated from the fixed fluid bath.
Further, the method also comprises the following steps:
a cleaning tank which is arranged side by side with the dye liquor tank along a first direction and is positioned at the other side of the dye liquor tank and used for arranging a cleaning box,
the washing box is provided with a plurality of slide inserting positions which are arranged along the second direction and can insert a slide,
the slide insertion sites of the wash cassette are all fluidly isolated from the wash tank.
Further, the tank cavities of the first dye tank and/or the second dye tank and/or the fixed tank comprise a lower cavity below having a first width in the second direction and an upper cavity above having a second width in the second direction greater than the first width,
the upper chamber is in fluid communication with the lower chamber.
Further, the first dye bath and/or the second dye bath keep the first basket body in a state that the lower cavity of the bath cavity accommodates the lower part of the first basket body.
Further, the upper cavity includes a first portion protruding from the lower cavity in the second direction and a second portion protruding from the lower cavity in a direction opposite to the second direction, and a width of the first portion in the second direction is greater than a width of the first portion in the second direction.
Furthermore, the two opposite sides of the first basket body are provided with first lug parts,
and first supporting columns for supporting the first lug parts of the first basket body are respectively arranged on the bottom groove walls of the first part and the second part of the first dye solution groove or the second dye solution groove.
Further, the first support column is a cylinder.
Further, also comprises
A first liquid level limiting column arranged at one of the first part and the second part and used for sucking dyeing liquid in the dyeing liquid groove in a negative pressure mode,
the dye liquor tank can be limited at a first liquid level through a negative pressure suction port of the first liquid level limiting column.
Further, also comprises
A second liquid level limiting column which is arranged on the other one of the first part and the second part and is provided with an overflow port leading to the outside of the dye liquor groove,
the dye liquor tank can be limited at a second liquid level through an overflow port of the second liquid level limiting column,
the second level is higher than the first level.
Further, the slide inserting positions of the first basket body arranged in the first dye groove and the second dye groove are used for holding the slide in a state that the slide printing area is arranged above the slide pushing area, the slide pushing area is arranged below the slide pushing area, and the bottom edge of the slide printing area is higher than the first liquid level.
Further, the first liquid level limiting column comprises:
a first column having a drain passage with one end in communication with a negative pressure source and the other end in fluid communication with the dye bath.
Further, the first liquid level limiting column further comprises:
a cover having a surrounding wall surrounding a water inlet of the liquid discharge passage of the first cylinder,
the inner wall of the surrounding wall forms a drainage cavity which contains the water inlet of the liquid discharge channel and is opened downwards, and the water inlet of the liquid discharge channel is communicated with the dye liquor groove through the drainage cavity.
Further, the bottom surface of the surrounding wall is parallel to the liquid level of the dye liquid stored in the dye liquid groove.
Furthermore, the cover body is in threaded connection with the first cylinder, an external thread is arranged on the cylinder part above the water inlet of the liquid drainage channel of the first cylinder, and a counter bore with an internal thread matched with the external thread is arranged on the bottom wall of the drainage cavity.
Further, the first cylinder is in threaded connection with the dye liquor tank.
Further, the second liquid level limiting column comprises an annular wall and an overflow channel which is formed by the inner wall of the annular wall and leads to the outside of the dye liquor tank,
the annular wall is provided with a gap to form the overflow port.
Furthermore, the fixed liquid groove keeps the second basket body in a state that the lower cavity of the groove cavity is used for accommodating the lower part of the second basket body.
Furthermore, the two opposite sides of the second basket body are provided with second lug parts,
and second support columns for supporting second lugs of the second basket body are respectively arranged on the bottom groove walls of the first part and the second part of the fixed liquid groove.
Further, the second support column is a square column.
Further, also comprises
And the transfer tank is arranged side by side with the dye tank along a second direction and is positioned on one side of the dye tank and used for caching at least one slide.
Further, the tank cavity of the first dye tank for storing the first dye solution includes a deep portion and a shallow portion adjacent to the deep portion in the second direction, the deep portion having a depth greater than that of the shallow portion, the deep portion being in fluid communication with the shallow portion,
the first dye solution tank holds the first basket body in a state that the first basket body is accommodated in the deep part.
Further, the shallow portions are provided adjacent to each other on both sides of the deep portion, and a width in the second direction of a first shallow portion adjacent to the intermediate transfer groove is smaller than a width in the second direction of a second shallow portion not adjacent to the intermediate transfer groove.
Further, the structure of the cavity of the second dye solution tank for storing the second dye solution is the same as that of the cavity of the first dye solution tank for storing the first dye solution.
Further, the slide insertion position holds the slide in a state where the width direction of the slide is kept coincident with the first direction,
the transfer slot buffers the slide in a state where a width direction of the slide is kept coincident with a first direction.
Further, the lower cavity has a funnel-shaped bottom wall,
the conical tip part of the bottom wall is provided with a liquid outlet.
Furthermore, a liquid inlet capable of injecting liquid into the groove cavity is formed in the conical surface of the bottom wall.
Furthermore, a flow guide column for guiding the liquid injected into the groove cavity is arranged at the liquid inlet,
the flow guide column is provided with a liquid inlet channel which is butted with the liquid inlet and extends along the axial direction of the flow guide column, and a liquid outlet which is communicated with the liquid inlet channel and can lead out the liquid entering the liquid inlet channel to the radial direction of the flow guide column.
Further, the method also comprises the following steps:
and the guide cylinder can be inserted into the overflow channel of the second liquid level limiting column and forms a micro-overflow channel with the channel wall of the overflow channel.
Furthermore, the inside of the guide column body is provided with a vent hole which penetrates through the guide column body along the axial direction of the guide column body.
Further, the method also comprises the following steps:
a cover plate capable of covering the first dye solution tank and/or the second dye solution tank and/or the fixed solution tank and having a slide insertion port fitted to the slide insertion site into which a slide is inserted into the slide insertion site,
and the cover plate is provided with a placement hole which corresponds to the position of the second liquid level limiting column and is used for inserting the guide column body into the overflow channel.
Further, the guide cylinder includes:
a cover portion having a sectional size larger than that of the seating hole, and
and the cross section of the drainage part is smaller than that of the placement hole.
Further, the method also comprises the following steps:
an overflow tank for receiving the staining solution and the fixing solution overflowing from the overflow channel,
and a drainage bulge which can contact with or form a gap with the bottom of the guide column body kept in the overflow channel is arranged at the bottom of the overflow channel.
Further, also comprises
A first cover plate capable of covering the dye bath,
the first cover plate is provided with a slide inserting opening for inserting the slide into the slide inserting position, which is matched with the slide inserting position on the first basket body arranged in the dye solution groove.
Further, also comprises
A flip plate capable of flipping between a covering position covering the slide insertion port on the first cover plate and an opening position opening the slide insertion port on the first cover plate, and
and the driving mechanism can drive the turnover plate to turn over.
Further, also comprises
Sealing rings arranged at the edges of the notches of the first dye solution tank and the second dye solution tank,
the first cover plate is arranged in the dye liquor tank in a mode of pressing the sealing ring to seal the notches of the first dye liquor tank and the second dye liquor tank.
Further, also comprises
A first cover plate capable of covering the dye bath,
a sealing gasket arranged on the surface of the first ear part,
the first cover plate is arranged in the dye solution groove in a mode of pressing the sealing gasket.
Further, the slide insertion position holds the slide in a state where the width direction of the slide is kept coincident with the first direction.
According to the slide glass manufacturing device provided by the invention, on one hand, the first dye solution groove and the second dye solution groove for dyeing the slide glass are arranged side by side along a first direction instead of being arranged into a line, the slide glass inserting positions in the first dye solution groove and the second dye solution groove are arranged in the first basket body along a second direction different from the first direction, so that the slide glass inserting positions in the whole dye solution groove are arranged in a matrix form, and the volume of the whole dye solution groove can be effectively reduced; on the other hand, the independent first basket bodies are arranged in the first dye solution tank and the second dye solution tank, and when the first basket bodies need to be cleaned, the first basket bodies are taken out and cleaned, so that the maintenance of a user is facilitated.
Drawings
FIG. 1 is a schematic block diagram of one embodiment of a slide making apparatus of the present application;
FIG. 2A is a top view of yet another embodiment of a slide preparation device of the present application;
FIG. 2B is a schematic block diagram of yet another embodiment of a slide preparation device of the present application;
FIG. 2C is a top view of yet another embodiment of a slide preparation device of the present application;
FIG. 2D is a schematic block diagram of yet another embodiment of a slide preparation device of the present application;
FIG. 3 is a schematic structural view of one embodiment of a cleaning cartridge of the present application;
FIG. 4 is a cross-sectional view of one embodiment of a dye bath of the present application;
FIG. 5 is a cross-sectional view of one embodiment of a slide making device of the present application;
FIG. 6 is a schematic block diagram of yet another embodiment of a slide preparation device of the present application;
FIG. 7A is a cross-sectional view of yet another embodiment of a slide making device of the present application;
FIG. 7B is a cross-sectional view of one embodiment of the first basket of the present application;
FIG. 7C is a schematic diagram illustrating an embodiment of a first basket of the present application;
FIG. 8 is a cross-sectional view of an embodiment of a first fluid level limiting column of the present application;
FIG. 9 is a cross-sectional view of an embodiment of a first fluid level limiting column of the present application;
FIG. 10A is a schematic diagram of an embodiment of a second fluid level limiting column of the present application;
FIG. 10B is a schematic diagram of a second embodiment of a second fluid level limiting column of the present application;
FIG. 10C is a top view of an embodiment of an isopipe of the present application;
FIG. 10D is a schematic structural view of an embodiment of a first cover plate of the present application;
FIG. 10E is a schematic structural view of one embodiment of a cover plate of the present application;
FIG. 11 is a schematic diagram illustrating an embodiment of a second basket of the present application;
FIG. 12A is a cross-sectional view of one embodiment of a dye bath of the present application;
FIG. 12B is a cross-sectional view of one embodiment of a slide making device of the present application;
FIG. 12C is a top view of one embodiment of a dye bath of the present application;
fig. 13 is a cross-sectional view of one embodiment of a flow post of the present application;
FIG. 14A is a schematic structural view of yet another embodiment of a slide preparation device of the present application;
FIG. 14B is a schematic block diagram of yet another embodiment of a slide preparation device of the present application;
FIG. 14C is a schematic structural view of yet another embodiment of a slide preparation device of the present application;
FIG. 15 is a schematic structural view of one embodiment of the roll-over panel of the present application;
fig. 16A, 16B, 16C are schematic structural views of one embodiment of a slide of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the following will explain in detail the slide glass manufacturing apparatus of the present invention by way of examples with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings). In the description of the present invention, it is to be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like, indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience of description and simplicity of description, and do not indicate or imply that the referenced mechanism or element must have a particular orientation, be constructed and operated in a particular orientation, and thus, should not be construed as limiting the present invention.
In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.
Fig. 1, 2A to 2D show a slide manufacturing apparatus according to an embodiment of the present disclosure. The slide glass fabricating apparatus is for performing a staining process on a slide glass S which is in a sheet shape as shown in fig. 16A, 16B and 16C, and has a width direction of S1, a thickness direction of S2 and a height direction of S3. The working surface of the slide glass S comprises a push area AR1 and a printing area AR2, sample push processing is carried out in the push area AR1, and a blood sample is coated on the push area AR1 in a blood film form; the print processing is performed in the print area AR2, and the sample information is printed in the print area AR2, which facilitates the user to recognize and read the information of the sample smeared on the slide. Generally, the slide S is subjected to the staining process while in the upright state (with the print area AR2 on top and the slide-pushing area AR1 on bottom), and the slide' S slide-pushing area AR1 is soaked with the staining solution.
The slide glass manufacturing apparatus according to the first embodiment of the present application includes a dye bath GD including a plurality of two or three bath cavities arranged side by side in a first direction, and as shown in fig. 1, a dye bath including three bath cavities, i.e., a first dye bath GD1, a second dye bath GD2, and a third dye bath GD3, will be described. The first, second, and third dye bath tanks GD1, GD2, and GD3 are arranged side by side along the first direction. The first dye bath tank GD1, the second dye bath tank GD2 and the third dye bath tank GD3 are independent of each other and are isolated from each other by fluid. The first dye solution tank GD1 is used for storing a first dye solution, the second dye solution tank GD2 is used for storing a second dye solution, and the third dye solution tank GD3 is used for storing a third dye solution; according to different dyeing modes, the first dye solution tank GD1, the second dye solution tank GD2 and the third dye solution tank GD3 can be filled with the same dyeing solution or different dyeing solutions; that is, the first, second, and third staining solutions may be different, the same, or partially the same or partially different (e.g., the first and second staining solutions are the same, and the first and second staining solutions are different from the third staining solution).
As shown in fig. 2A, the first basket bodies (BD1, BD2, BD3) are disposed in the first dye bath GD1, the second dye bath GD2, and the third dye bath GD3, and the structures of the first basket bodies disposed in the three bath cavities may be the same or different. Each first basket body is provided with a plurality of slide inserting positions (SP21, SP22 and SP23) (for example, 5, 6, 7 and 8) arranged along the length direction of the first basket body, each slide inserting position can be inserted with one slide S, and all the slide inserting positions of each first basket body are communicated with the groove cavity in which the first basket body is positioned in a fluid mode, namely, after the slide is inserted into the slide inserting position, staining solution in the groove cavity can soak the slide. The first basket body BD1 is set in the first dye bath GD1 with its plural slide insertion positions arranged in a second direction different from the first direction; similarly, the second basket body BD2 is disposed in the second dye bath GD2 in a state where a plurality of slide insertion positions are arranged in the second direction, and the third basket body BD3 is disposed in the third dye bath GD3 in a state where a plurality of slide insertion positions are arranged in the second direction; thus, the slide inserting positions arranged in a matrix form can be formed in the whole dye bath, and the volume of the whole dye bath can be reduced. The second direction is preferably orthogonal to the first direction, and the technical solution of the present application will be described in the embodiment of the present application by taking the first direction orthogonal to the second direction as an example.
Specifically, as shown in fig. 2A to 2D, the first basket body BD1 disposed in the cavity of the first dye bath GD1 has 8 slide insertion sites SP21 arranged in the second direction, and each slide insertion site SP21 of the first basket body BD1 is in fluid communication with the first dye bath GD1, i.e., the first dye solution stored in the first dye bath GD1 can be soaked into the slide inserted in the slide insertion site SP 21. The first basket body BD2 disposed in the cavity of the second dye bath GD2 also has 8 slide insertion sites SP22 arranged in the second direction, and each slide insertion site SP22 of the first basket body BD2 is in fluid communication with the second dye bath GD2, i.e., the second dye solution stored in the second dye bath GD2 can be soaked into the slide inserted in the slide insertion site SP 22. The first basket body BD3 disposed in the cavity of the third dye bath GD3 also has 8 slide insertion sites SP23 aligned in the second direction into which a slide can be inserted, and the slide insertion site SP23 of the first basket body BD3 is in fluid communication with the third dye bath GD3, i.e., the third dye solution stored in the third dye bath GD3 can be soaked into the slide inserted into the slide insertion site SP 23.
When the first staining process is required to be performed on the slide glass S on which the methanol fixing process is performed, the slide glass S on which the methanol fixing process is performed is inserted into the slide insertion position SP21 of the first basket body BD1 in the first staining solution tank GD1, the first staining solution stored in the first staining solution tank GD1 can soak the slide glass S inserted into the slide insertion position SP21, and after a certain period of soaking time, the first staining process is completed;
when the second staining process is required to be performed on the slide glass S, the slide glass S is inserted into the slide glass insertion position SP22 of the first basket body BD2 in the second staining solution tank GD2, the second staining solution stored in the second staining solution tank GD2 can be soaked into the slide glass S inserted into the slide glass insertion position SP22, and after a certain period of soaking time, the second staining process is completed;
when the third staining process is required to be performed on the slide glass S, the slide glass S is inserted into the slide insertion position SP23 of the first basket body BD3 in the third stain tank GD3, and the third staining solution stored in the third stain tank GD3 can be soaked in the slide glass S inserted into the slide insertion position SP23, and after a certain period of soaking time, the third staining process is completed.
As described above, the first dyeing process, the second dyeing process, and the third dyeing process may be the same dyeing process or different dyeing processes. For example, if only one dyeing solution is required for a certain dyeing mode, the same dyeing solution may be injected into the first, second, and third dye tanks GD1, GD2, and GD3, or the dyeing solution may be injected into one or both of the first, second, and third dye tanks GD1, GD2, and GD 3; if three dyeing liquids are required in a certain dyeing mode, different dyeing liquids are injected into the first dye liquid tank GD1, the second dye liquid tank GD2 and the third dye liquid tank GD 3; if two kinds of dyeing liquids are required for a certain dyeing mode, one kind of dyeing liquid may be injected into one of the first, second, and third dyeing liquid tanks GD1, GD2, and GD3, and the other two kinds of dyeing liquids may be injected into the other dyeing liquid.
When three staining solutions are needed to treat the glass slide, different staining solutions are injected into the first staining solution tank GD1, the second staining solution tank GD2 and the third staining solution tank GD3, and the staining treatment is sequentially performed on the glass slide according to the sequence of the first staining treatment, the second staining treatment and the third staining treatment, namely, the glass slide is sequentially transferred among the first staining solution tank GD1, the second staining solution tank GD2 and the third staining solution tank GD 3.
As shown in fig. 1, a slide glass fabricating apparatus according to still another embodiment of the present application further includes a fixing liquid tank GH for storing a fixing liquid (e.g., a methanol fixing liquid), the fixing liquid tank GH being arranged side by side with the dye tanks (the first dye tank GD1, the second dye tank GD2, and the third dye tank GD3) in the first direction, and being adjacent to the dye tanks. As shown in fig. 2A to 2D, a second basket body BH having a plurality of (for example, 6) slide insertion positions arranged along its length direction at which a slide can be inserted is disposed in the chamber of the fixed liquid bath GH, and the second basket body BH is disposed in the fixed liquid bath GH with its plurality of slide insertion positions arranged along the second direction. Wherein, the 6 slide inserting positions comprise 4 first slide inserting positions SP11 which can be communicated with the fluid of the fixed fluid groove GH and 2 second slide inserting positions SP12 which are isolated from the fluid of the fixed fluid groove GH; the first type slide insertion position SP11 provides a working position for performing a methanol fixing process on the slide S, and the second type slide insertion position SP12 is used for performing a methanol drying process on the slide S.
When the slide glass S which is processed by the sample push piece processing needs to be processed by the fixing processing, the slide glass S which is processed by the sample push piece processing is inserted into a first type slide inserting position SP11 of a second basket body BH in a fixing liquid groove GH, the methanol fixing liquid stored in the fixing liquid groove GH can soak the slide glass S which is inserted into a first type slide inserting position SP11, after the soaking for a certain time, the slide glass S is transferred to a second type slide inserting position SP12 of the second basket body BH in the fixing liquid groove GH, the second type slide inserting position SP12 is provided with an air outlet communicated with an air source, and the slide glass S is processed by the methanol drying operation through the air flow blown out of the air outlet.
As shown in fig. 1 and fig. 2A to 2D, a slide glass fabricating apparatus according to still another embodiment of the present application further includes a cleaning tank GC for housing the cleaning cassette CB, and the fixed liquid tank GH, the dye liquid tank, and the cleaning tank GC are arranged in parallel along a first direction. The washing cassette CB has a plurality of (e.g., 2) slide insertion sites SP3 capable of inserting one slide arranged along its length direction, and is set in the washing bath GC in a state where the plurality of slide insertion sites SP3 are arranged along the second direction; the slide insertion sites SP3 of the wash cassette disposed within the wash tank GC are all fluidly isolated from the wash tank.
Specifically, a plurality of slide insertion positions SP3 may be provided on one washing box CB, and when mounting, the washing box CB is integrally fixed to the mounting plate MP; alternatively, a plurality of independent washing cases CB may be provided, each of which is provided with a slide insertion position SP3, and the independent washing cases CB are fixed to the mounting plate MP, respectively, at the time of mounting.
For ease of processing and ease of mounting, the present embodiment preferably provides a plurality of washing cassettes CB, each of which is provided with a slide insertion site SP 3. As shown in fig. 2A to 2D, each of the washing cassettes CB is fixed to a mounting plate MP, and is then placed in the washing bath GC together with the mounting plate MP, the mounting plate MP covering the notch of the washing bath GC, and the mounting plate MP having a reserved opening (insertion opening) for inserting the slide S into the slide insertion position SP 1. The surfaces of the two end parts of the mounting plate MP are provided with water absorption sponges, the positions of the washing tank GC corresponding to the water absorption sponges are provided with washing leakage detection electrodes 1 and washing leakage detection electrodes 2, and the two electrode tips of the washing leakage detection electrodes 1/the washing leakage detection electrodes 2 are inserted into the corresponding water absorption sponges. When the cleaning solution in the cleaning tank GC overflows the notch of the cleaning tank GC, the overflowing liquid is firstly absorbed by the water absorption sponge, the two electrode tips of the cleaning leakage detection electrode 1/the cleaning leakage detection electrode 2 are conducted, and a leakage warning signal is sent to a user/an upper computer.
As shown in fig. 3, the slide insertion position SP3 on the cleaning cassette CB is a reservoir CB1 having an upward opening, and a cleaning liquid can be stored in the reservoir CB1 and a slide S can be inserted into the reservoir CB 1. A side wall plate of the cleaning cassette CB defining a slide insertion position SP3 is provided with a cleaning liquid nozzle CN capable of ejecting a cleaning liquid onto a slide S inserted at a slide insertion position SP3, and a bottom wall plate of the cleaning cassette CB defining a slide insertion position SP3 is provided with a cleaning liquid negative pressure suction port NP for sucking away the cleaning liquid ejected from the cleaning liquid nozzle CN to the slide insertion position SP 3. An overflow cavity CB2 adjacent to the slide inserting position SP3 is arranged on the cleaning box CB, the liquid level of the cleaning liquid in the liquid storage cavity exceeds the top opening of the liquid storage cavity and then overflows into the overflow cavity CB2, a cleaning liquid discharge port AP is arranged at the bottom of the overflow cavity CB2, and the overflowing cleaning liquid is discharged through the cleaning liquid discharge port.
When the slide glass S needs to be cleaned, the slide glass S is inserted into a slide glass insertion position SP3 on a cleaning box CB in a cleaning tank GC, a cleaning solution nozzle CN ejects a cleaning solution to the slide glass to clean the slide glass, the cleaning solution ejected to the slide glass insertion position SP3 is pumped out through a cleaning solution negative pressure suction port NP, can be pumped into a waste liquid pool, and then is discharged out of the slide glass processing apparatus through the waste liquid pool.
The first, second, third and fixed tanks may be identical or different in structure, and in another embodiment of the present invention, the first, second, third and fixed tanks are identical in structure.
In the present embodiment, the first dye bath GD1 is taken as an example, and the structures of the first dye bath, the second dye bath, the third dye bath, and the fixed bath will be described. As shown in fig. 4, the bottom wall of the cavity of the whole first dye bath GD1 is funnel-shaped, and a liquid outlet LO is arranged at the conical tip of the funnel-shaped bottom wall; a liquid inlet LI capable of injecting liquid into the groove cavity is arranged on the conical surface of the funnel-shaped bottom wall. The first dyeing liquid is injected into the first dyeing liquid tank GD1 through the liquid inlet LI, and is discharged out of the first dyeing liquid tank GD1 through the liquid outlet LO. When the first staining process is performed for the first time, an appropriate amount of the first staining solution is injected into the first staining solution tank GD1 through the solution inlet LI so that the liquid surface of the first staining solution in the first staining solution tank GD1 is not higher than the slide pushing area AR1 of the slide S of the slide insertion position SP21 of the first basket body BD1 inserted into the first staining solution tank GD 1. As the number of slides on which the first dyeing process is performed in the first dye bath GD1 increases, the first dyeing liquid in the first dye bath GD1 is gradually decreased, and the first dyeing liquid may be replenished into the first dye bath GD1 through the liquid inlet LI in real time. When the first dye liquid tank GD1 needs to be maintained and cleaned, the first dye liquid in the first dye liquid tank GD1 is discharged out of the first dye liquid tank GD1 through the liquid outlet LO, and the funnel-shaped bottom wall can enable the first dye liquid in the first dye liquid tank GD1 to be discharged out quickly.
Preferably, in order to reduce the amount of the dyeing liquid, as shown in fig. 4 and 5, the cavity of the first dye bath GD1 includes a lower cavity G1 and an upper cavity G2, the upper cavity G2 is located above the lower cavity G1 and is bounded by a dotted line in fig. 4, a portion above the dotted line is the upper cavity G2, and a portion below the dotted line is the lower cavity G1. The upper chamber G2 has a width W2 in the second direction, the lower chamber G1 has a width W1 in the second direction, W2 > W1, and the upper chamber G2 is in fluid communication with the lower chamber G1. As shown in fig. 5, the first dye bath GD1 holds the first basket body BD1 in a state where the lower cavity G1 of the bath cavity receives most of the basket body of the first basket body BD 1. As shown in fig. 6, most of the basket body of the first basket body BD1 is retained within the lower cavity G1 such that most of the slide S pushing area AR1 to be stained is located just within the lower cavity G1; as shown in fig. 5, H1 represents the liquid level height of the first staining solution when no slide is inserted in the first staining solution tank GD1, and the height H1 is a height necessary for performing the first staining process; when the slides are inserted into all the slide insertion positions SP21 on the first basket body BD1 in the first dye bath GD1, the liquid level of the first dye solution rises by about 3mm based on the height H1, and the liquid level does not reach the area where the printing area AR2 is located. As can be seen from fig. 5 and 6, the structure with wide top and narrow bottom can concentrate most of the staining solution in the lower chamber G1, and a small amount of staining solution is located in the upper chamber G2, so that on one hand, the amount of staining solution used can be reduced, and on the other hand, since the liquid level of the first staining solution is located in the upper chamber G2, the width W2 of the upper chamber G2 in the second direction is larger, so that the liquid level area of the first staining solution is larger, the fluctuation of the liquid level of the first staining solution can be reduced, and the change of the liquid level height caused by the insertion of the slide glass can also be reduced.
More specifically, as shown in fig. 4, the upper chamber G2 includes a first portion G21 protruding from the lower chamber G1 in the second direction and a second portion G22 protruding from the lower chamber G1 in the fourth direction (opposite to the second direction), and a width W22 of the second portion G22 in the second direction is greater than a width W21 of the first portion G21 in the second direction. In the first dye bath GD1 having such a configuration, a large space for the chamber is reserved in the fourth direction above the chamber, and other members (for example, an overflow groove OW described later is provided below the second portion G22) may be provided at positions corresponding to the space region, thereby realizing a rational layout of the entire first dye bath GD 1. By reserving a small cavity space in the second direction above the cavity, the distance from a transfer tank (provided on one side in the second direction of the dye solution tank) described later can be reduced, thereby reducing the stroke of the gripper for transferring the slide glass and improving the transfer efficiency of the slide glass.
In order to facilitate the installation of the first basket body BD1, as shown in fig. 7A, 7B and 7C, first ears EP1 are disposed on opposite sides of the first basket body BD1, two first ears EP1 are symmetrically disposed, and the first ears EP1 are formed by extending a top edge of the first basket body BD1 on a side of the arrangement direction of the slide insertion positions SP21 to the outside of the basket body; first support columns SPP1 for supporting the first ears EP1 are provided at corresponding positions on the first dye bath GD1, and when the first basket body BD1 is mounted, the first ears EP1 rest on the corresponding first support columns SPP 1.
Preferably, first supporting columns SPP1 for supporting the first ear EP1 of the first basket body BD1 are respectively provided on bottom groove walls of the first portion G21 and the second portion G22 of the first dye bath tank GD 1. The first support column is preferably a cylinder, which can reduce the residue of the staining solution on the first support column SPP 1. Of course, the first support columns SPP1 may be disposed at other suitable positions of the first dye bath GD 1.
Specifically, in order to accurately control the working liquid level height H1 of the first dyeing liquid in the first dye liquid tank GD1, as shown in fig. 1 and 5, a first liquid level limiting column LC1 is provided in the first dye liquid tank GD1, a negative pressure suction port NP1 capable of sucking the dyeing liquid in the first dye liquid tank GD1 in a negative pressure manner is provided on the first liquid level limiting column LC1, and the dyeing liquid in the first dye liquid tank GD1 can be limited to the first liquid level (the working liquid level height H1) by reasonably providing the negative pressure suction port NP1 of the first liquid level limiting column LC 1.
Specifically, as shown in fig. 8, the first liquid level limiting column LC1 includes a first column LC1-1, and the first column LC1-1 has a liquid discharge passage DF therein, one end of which is in fluid communication with a negative pressure source (not shown) and the other end of which is in fluid communication with the first dye bath GD 1. The first dyeing liquid in the first dyeing liquid tank GD1 enters the liquid discharge channel through the water inlet WI of the liquid discharge channel DF, and is pumped out of the first dyeing liquid tank GD1 through the liquid outlet of the liquid discharge channel DF. In order to maintain the first dyeing liquid in the first dyeing liquid tank GD1 at the first liquid level, the water inlet WI may be set at the working liquid level H1, and once the first dyeing liquid reaches the working liquid level H1 and tends to exceed the working liquid level H1, the first dyeing liquid in the first dyeing liquid tank GD1 is pumped away by the negative pressure of the drainage channel DF so as to maintain the first dyeing liquid in the first dyeing liquid tank GD1 at the first liquid level H1. Of course, the negative pressure source of the drain passage DF may be intermittently turned on and off for energy saving.
Specifically, as shown in fig. 9, the liquid discharge passage DF includes a first passage portion DF1 extending along the axis of the first cylinder LC1-1, and further includes a second passage portion DF2 penetrating the first cylinder LC1-1 in the radial direction of the first cylinder LC1-1, the second passage portion DF2 communicating with the first passage portion DF1 to form a T-shaped passage. The openings at both ends of the second passage portion DF2 constitute the water inlet WI of the liquid discharge passage DF.
In order to more precisely control the working liquid level height H1 of the first dyeing liquid in the first dye liquid tank GD1, as shown in fig. 9, the first liquid level limiting column LC1 further includes a cover body CM including a surrounding wall CM-1 surrounding the water inlet WI of the liquid discharge channel DF, the surrounding wall CM-1 forming a cavity with an opening facing downward, the cavity constituting a drainage cavity CM-2 containing the water inlet WI of the liquid discharge channel DF and opening downward, the water inlet of the liquid discharge channel DF being in fluid communication with the first dye liquid tank GD1 through the drainage cavity CM-2. The wall surface (suction surface FL) of the surrounding wall forming the opening of the drainage chamber CM-2 is parallel to the horizontal plane, that is, the bottom surface (suction surface FL) of the lid CM is parallel to the surface of the dye solution stored in the dye solution tank in the orientation shown in fig. 9. When the liquid level of the first dyeing liquid exceeds the liquid absorption surface, a closed environment is formed between the liquid absorption surface FL and the water inlet WI, and the first dyeing liquid is absorbed into the liquid drainage channel DF under the action of negative pressure in the liquid drainage channel DF, so that redundant first dyeing liquid is discharged, and the accurate control of the liquid level height is realized. Further, the water inlet WI is higher than the liquid suction surface FL, and the first staining solution can be prevented from contacting the water inlet WI for a long time, thereby reducing the risk of clogging of the water inlet WI with staining residues.
Specifically, for the sake of convenience of installation, as shown in fig. 8, the cover CM is screwed to the first cylinder LC1-1, an external thread is provided on the upper cylinder portion of the water inlet WI of the drainage passage DF of the first cylinder LC1-1, and a counter bore having an internal thread that mates with the external thread on the first cylinder LC1-1 is provided on the bottom wall of the drainage chamber CM-2 opposite to the liquid suction surface FL. During installation, the cover body CM is covered on the top of the first column LC1-1, and the cover body CM is screwed down to realize the sealing connection between the cover body CM and the first column LC 1-1.
Specifically, for convenience of installation, the first liquid level limiting column LC1 is in threaded connection with the first dye liquor tank GD1, as shown in fig. 8, an external thread is arranged on the periphery of the first column LC1-1, and a connecting hole (not shown in the figure) with an internal thread, which is communicated with a negative pressure source, is arranged at a corresponding position on the first dye liquor tank GD 1. When the liquid level limiting column LC1 is installed, the first liquid level limiting column LC1 is screwed into the connecting hole.
Preferably, the first liquid level limiting column LC1 is arranged on the bottom wall of the first part G21 or the second part G22, and a connecting hole with internal threads communicated with the negative pressure source is formed at a corresponding position of the bottom wall of the first part G21 or the second part G22. In the present embodiment, as shown in fig. 1 and 4, a first liquid level limiting column LC1 is provided on the bottom wall of the first part G21.
Specifically, in order to control the liquid level of the first cleaning liquid in the first dye tank GD1 to the second liquid level H2 as shown in fig. 5, a second liquid level stopper LC2 having an overflow passage OP leading to the outside of the first dye tank GD1 is provided on the bottom wall of the second portion G22, and the liquid level of the first cleaning liquid in the first dye tank GD1 can be controlled to the second liquid level H2 by appropriately setting the height of an overflow port OH of the overflow passage OP.
The second liquid level H2 is a liquid level height when the dyeing tank is maintained, that is, when the dyeing tank needs to be cleaned and maintained, the dyeing liquid in the dyeing tank is drained, the cleaning liquid is injected into the dyeing tank, and the liquid level of the cleaning liquid reaches the height of the second liquid level H2, and the height of the second liquid level H2 is greater than the height of the first liquid level H1. When the dyeing tank is cleaned and maintained, the negative pressure source of the first liquid level limiting column LC1 needs to be closed.
The spacing post LC2 of second liquid level has another effect, when the dye vat is carrying out dyeing work, if the water inlet WI of the spacing post LC1 of first liquid level is stopped up by the dyestuff sediment, or other trouble has appeared, make the spacing post LC1 of first liquid level can not normally work, dye liquor can not discharge through the spacing post LC1 of first liquid level in first dye vat GD1, dye liquor liquid level height can exceed the height of first liquid level H1, when dye liquor liquid level height reaches second liquid level H2 height, the part of rising will be discharged outside first dye vat GD1 through the overflow mouth OH of the spacing post LC2 of second liquid level, prevent that dye liquor from overflowing first dye vat GD 1.
Specifically, as shown in fig. 10A, the second liquid level controlling column LC2 includes an annular wall RW and an overflow path OP formed by an inner wall of the annular wall RW and leading to the outside of the first dye liquid tank GD1, the annular wall RW is notched to form an overflow port OH, and the overflow path OP penetrates through the bottom wall of the second portion G22.
Specifically, in order to improve the overflow effect of the second liquid level limiting column LC2, as shown in fig. 10B, the slide glass manufacturing apparatus according to the further embodiment of the present application further includes a guide cylinder GP that can be inserted into the overflow path OP of the second liquid level limiting column LC2 and forms a micro-overflow path OP with the channel wall of the overflow path OP. The outer diameter of the cylinder portion of the guide cylinder GP inserted into the overflow path OP is smaller than the diameter of the overflow path OP, so that a gap is formed between the cylinder portion of the guide cylinder GP inserted into the overflow path OP and the wall of the overflow path OP, and the gap may generate a capillary action, so that the dyeing liquid in the first dye bath GD1 more easily flows into the overflow path OP to be discharged out of the first dye bath GD 1.
Specifically, the slide glass S is held at the slide glass insertion positions (SP21, SP22, SP23) of the first basket body (BD1, BD2, BD3) disposed in the first, second, and third dye tanks GD1, GD2, GD3 in a state where the slide glass printing region AR2 is up, the slide pushing region AR1 is down, and the bottom edge of the printing region AR2 is higher than the first liquid level H1. Thus, the print area AR2 is not contaminated when the staining process is performed on the slide.
The structures of the second dye solution tank GD2, the third dye solution tank GD3, and the fixed solution tank GH are the same as those of the first dye solution tank GD1, and the structures of the second dye solution tank GD2, the third dye solution tank GD3, and the fixed solution tank GH are not described in detail.
However, since the second basket body BH has a different structure from that of the first basket body BD1, the support columns in the fixed bath GH for accommodating the second basket body BH and the first support columns SPP1 in the first bath GD1 for accommodating the first basket body BD1 may have different structures. Specifically, as shown in fig. 1 and 11, the second ears EP2 are disposed on opposite sides of the second basket BH, the two second ears EP2 are symmetrically disposed, and the second ears EP2 are formed by extending the top edge of the second basket BH on the side of the slide insertion position SP22 in the arrangement direction to the outside of the basket. The second lug portion EP2 is simple plate-shaped and easily deformable as compared with the first lug portion EP 1. Therefore, the second support pole SPP2 provided in the stationary liquid groove GH for seating the second basket body BH has a square column shape (square column shape), and the contact area with the second lug EP2 can be increased, and the deformation of the second lug EP2 can be reduced. Two second support posts SPP2 are provided on the bottom slot walls of the first and second portions of the fixed liquid slot GH, respectively, and the second basket body BH is mounted with the second ears EP2 resting on the corresponding second support posts SPP 2. And the fixed liquid groove GH keeps the second basket body BH in a state that the lower cavity of the groove cavity is used for accommodating the lower part of the second basket body BH.
In order to prevent the fixing liquid in the fixing liquid bath GH from evaporating, as shown in fig. 2A to 2D, the slide glass fabricating apparatus of the further embodiment of the present application further includes a cover plate BF capable of covering the fixing liquid bath GH, and a slide insertion port for inserting the slide glass S into the slide insertion position SP21 is provided at a corresponding position on the cover plate BF to be fitted with the slide insertion position SP 21.
During installation, the second basket body BH is firstly arranged in the fixed liquid groove GH, the second lug EP2 of the second basket body BH is placed on the corresponding second support column SPP2, and then the cover plate BF is pressed on the notch of the fixed liquid groove GH. Meanwhile, by properly setting the height of the second support pole SPP2, the cover plate BF can be made to just press the second ear EP2 of the second basket body BH so as to correct the slight deformation of the second ear EP 2.
Similarly, in order to prevent evaporation of the dye solution in the first, second, and third dye solution tanks GD1, GD2, and GD3, a cover plate capable of covering the opening of each of the first, second, and third dye solution tanks GD1, GD2, and GD3 may be separately provided. Of course, a common cover plate may be provided for the first, second, and third dye bath tanks GD1, GD2, and GD3, and as shown in fig. 2C and 2D, the slide glass preparing apparatus according to still another embodiment of the present invention further includes a first cover plate BF1 capable of covering the first, second, and third dye bath tanks GD1, GD2, and GD3, and the first cover plate BF1 is provided with a slide insertion port into which the slide glass S is inserted, the slide insertion port being engaged with slide insertion positions (SP21, SP22, and SP23) provided on the first basket body (BD1, BD2, and BD3) in the dye bath. 8 slide insertion ports are provided in a first cover plate BF1 region corresponding to the first dye bath GD1, 8 slide insertion ports are provided in a first cover plate BF1 region corresponding to the second dye bath GD2, and 8 slide insertion ports are provided in a first cover plate BF1 region corresponding to the third dye bath GD 3. The 24 slide insertion ports on the first cover plate BF1 are arranged in a matrix of 8 rows and 3 columns, that is, after the first basket body BD1, the first basket body BD2 and the first basket body BD3 are respectively placed in the first dye solution groove GD1, the second dye solution groove GD2 and the third dye solution groove GD3, the slide insertion position SP21, the slide insertion position SP22 and the slide insertion position SP23 form a matrix of 8 rows and 3 columns. The slide inserting positions in the dye solution groove with the structure are relatively concentrated, so that the stroke of a gripper for transferring the slide can be reduced, and the transfer efficiency of the slide is improved.
During installation, the first basket body BD1, the first basket body BD2 and the first basket body BD3 are respectively placed in the first dye solution groove GD1, the second dye solution groove GD2 and the third dye solution groove GD3, the first lug parts EP1 of the first basket body BD1, the first basket body BD2 and the first basket body BD3 are respectively placed on the corresponding first supporting columns SPP1, and then the first cover plate BF1 covers the notches of the first dye solution groove GD1, the second dye solution groove GD2 and the third dye solution groove GD3 and is fixed through screws. By properly setting the height of the first support pole SPP1, the first cover plate BF1 can be made to just press the first basket body BD1, the first basket body BD2, and the first ear EP1 of the first basket body BD 3.
Further, as shown in fig. 7B and 10D, a positioning protrusion EP1-1 is disposed on an upper surface of the first ear EP1, a positioning mounting hole LH matched with the positioning protrusion EP1-1 is disposed on the first cover plate BF1, and after the first cover plate BF1 is mounted on the dyeing tank, the positioning protrusion EP1-1 is just located in the positioning mounting hole LH (to achieve positioning of the first basket body BD1 in the horizontal direction), so as to press the first ear EP1 (to achieve positioning of the first basket body BD1 in the vertical direction).
Of course, the first dye bath GD1, the second dye bath GD2, the third dye bath GD3, and the fixed bath GH may share a single cover.
As described above, the first dye solution tank GD1, the second dye solution tank GD2, the third dye solution tank GD3, and the fixed solution tank GH are each provided therein with the second liquid level limiting column LC2 for guiding the liquid in the tank cavity to the outside of the tank cavity, and specifically, as shown in fig. 10C, an overflow groove OW for receiving the dyeing liquid/the fixed liquid flowing out from the overflow channel OP is provided below the second liquid level limiting column LC2 in each tank cavity, and the four second liquid level limiting columns LC2 share one overflow groove OW.
In order to further enhance the overflow effect, as shown in fig. 10C, a flow-guiding protrusion OW-1 capable of contacting or forming a gap between the bottom of the guide cylinder GP held in the overflow path OP is provided at the bottom of the overflow groove OW. The drainage protrusion OW-1 extends upwards from the bottom of the overflow groove OW and is infinitely close to the bottom of the guide cylinder GP, so that a micro gap is formed between the drainage protrusion OW-1 and the guide cylinder GP, and the micro gap can generate a capillary action, thereby further improving the overflow effect of the overflow channel OP.
Preferably, in order to balance the air pressure in the overflow OW, as shown in fig. 10B, the inside of the guide cylinder GP has a vent hole GP-1 axially penetrating the guide cylinder GP along the guide cylinder GP.
Specifically, in order to facilitate installation of the guide cylinder GP, the guide cylinder GP comprises a cover part GP-2 and a drainage part GP-3, the diameter of the cover part GP-2 is larger than that of the drainage part GP-3, and the drainage part GP-3 can be inserted into the overflow channel OP. As shown in FIGS. 10D and 10E, a setting hole IH into which the guide cylinder GP is inserted is reserved on a first cover plate BF1 covering the first dye solution tank, the second dye solution tank and the third dye solution tank and on a cover plate BF covering the fixed solution tank, and the sectional dimension (diameter) of the setting hole IH is smaller than that of the cover part GP-2 and larger than that of the drainage part GP-3. During installation, the guide column body GP is inserted into the installation hole IH, and then the guide column body GP-2 can be hung on the first cover plate BF 1/cover plate BF through the cover part, so that the installation is convenient.
In order to prevent the dyeing liquid or the dyeing slag from climbing out of the dye vat through the first basket body, as shown in fig. 7A, a sealing gasket GS1 is arranged on the surface of the first ear EP1, and by reasonably setting the height of the first support column SPP1, the sealing gasket GS1 on the surface of the first ear EP1 of the first basket body BD1, BD2 and BD3 can be just pressed by the first cover plate BF1, that is, the first cover plate BF1 is arranged in the dye vat in a manner of pressing the sealing gasket GS 1.
Similarly, in order to prevent the dyeing liquid or the dyeing slag from climbing to the groove wall of the adjacent dye solution tank through the groove wall of the dye solution tank to cause cross contamination, as shown in fig. 7A, sealing rings GS2 are respectively arranged on the edge of the respective notches of the first dye solution tank GD1, the second dye solution tank GD2 and the third dye solution tank GD3, and a first cover plate BF1 is arranged in the dye solution tank in a manner of pressing the sealing rings GS2, so that the sealing connection is formed with the edge of the notch of the first dye solution tank GD1, the second dye solution tank GD2 and the third dye solution tank GD3, and the dyeing liquid or the dyeing slag can be effectively prevented from climbing to the groove wall of the adjacent dye solution tank through the groove wall of the dye solution tank.
In order to facilitate the scheduling of the slides in different modes and improve the transfer efficiency of the slides, as shown in fig. 2B, a slide making apparatus according to another embodiment of the present disclosure further includes a transfer slot TG, and the transfer slot TG and the dye bath are adjacently disposed along the second direction, preferably, as shown in fig. 2D, the transfer slot TG is adjacently disposed with a second dye bath GD2 in the dye bath along the second direction, and is located on a side wall of the whole dye bath body, and at least one slide S may be buffered in the transfer slot TG. And for the slide glass which does not need to be dyed, the slide glass can be inserted into the transfer groove TG for caching, after the hand grip for transferring the slide glass is idle, the slide glass in the transfer groove TG is transferred to the next station, and the slide glass is conveyed to the taking-out position of the slide glass manufacturing device by the conveying mechanism. Thus, the staining treatment in the staining tank can be unaffected, and the transfer efficiency of the slide glass is improved.
As shown in fig. 12A and 12B, the tank chambers of the first/second/third dye tanks include deep portions TP and shallow portions, the shallow portions are disposed adjacent to the deep portions TP in the second direction, the shallow portions include first shallow portions QP1 and second shallow portions QP2, and the second shallow portions QP2, the deep portions TP, and the first shallow portions QP1 are sequentially disposed adjacent to each other in the second direction. The depth of the deep portion TP is greater than the depth of the shallow portion, the trough bottom of the shallow portion is higher than the trough bottom of the deep portion TP, and the shallow portion is in fluid communication with the deep portion TP. The first dye tank/the second dye tank/the third dye tank hold the first basket body in a state where the first basket body is accommodated in the penetration portion. A pair of first ears EP1 of the first basket everting toward the basket rest on first support posts SPP1 located at a first shallow QP1 and a second shallow QP2, respectively. Thus, most of the staining solution used in the cavity of the staining solution tank is concentrated in the deep part TP, and the consumption of the staining solution can be reduced.
Specifically, in order to make the layout of the slide insertion position and the transfer slot TG in the staining bath more concentrated, as shown in fig. 12C, the first shallow part QP1 of the first staining bath is adjacent to the transfer slot TG in the second direction, and the width of the first shallow part QP1 in the second direction is smaller than the width of the second shallow part QP2 in the second direction. Therefore, the first basket body is closer to the transfer groove TG in the second direction, the insertion positions of all the slide sheets on the first basket body and the transfer groove TG are more concentrated, and the stroke of a gripper for transferring the slide sheets can be reduced.
Specifically, as shown in fig. 2B, 2D, and 6, the slide insertion site of the first basket body disposed in the dye bath mounts the slide holder in a state where the width direction of the slide is consistent with the first direction, the slide insertion site of the second basket body disposed in the fixed bath mounts the slide holder in a state where the width direction of the slide holder is consistent with the first direction, the slide insertion site of the cleaning cassette disposed in the cleaning bath mounts the slide holder in a state where the width direction of the slide holder is consistent with the first direction, and the transfer bath buffers the slide holder in a state where the width direction of the slide holder is consistent with the first direction. So, settle the width direction of the slide glass in fixed cistern, dye liquor groove, washing tank and keep unanimous, at each tank cavity, arrange along the thickness direction of slide glass for the range of slide glass is more concentrated, has further reduced the stroke of the tongs that is used for shifting slide glass.
In order to reduce the impact force of the liquid injected into the tank cavity when the dyeing solution or other liquids are injected into the dyeing tank, as shown in fig. 12C and 13, a flow guide column DC for guiding the liquid injected into the tank cavity is disposed at the liquid inlet LI, and the flow guide column DC has a liquid inlet channel DC-1 butted with the liquid inlet LI and extending axially along the flow guide column, and a liquid outlet port DC-2 in fluid communication with the liquid inlet channel DC-1 and capable of guiding the liquid entering the liquid inlet channel DC-1 out radially of the flow guide column DC. As shown in fig. 13, the liquid lead-out port DC-2 is formed by two ports penetrating the through hole of the guide post DC in the radial direction, the through hole penetrating the guide post DC in the radial direction forms a T-shaped channel together with the liquid inlet channel DC-1, the liquid flowing out from the liquid inlet channel DC-1 is diffused to both sides of the guide post DC, the impact force of the changed liquid flowing backward is buffered, and the liquid is prevented from splashing in the groove cavity.
In order to reduce evaporation of the staining solution in the staining bath, as shown in fig. 14A to 14C, a slide glass manufacturing apparatus according to another embodiment of the present application further includes a flip plate FG that can be flipped between a cover position and an open position. When the flip plate FG is flipped to the covering position shown in fig. 14C, the flip plate FG covers the entire dye bath so as to cover the slide insertion port of the first cover plate BF 1; when the turnover plate FG is turned to the open position, the whole dye bath can be opened, so that the cover of a slide insertion opening on the first cover plate is removed, the operation of a gripper for transferring the slide glass in the dye bath cannot be interfered, and the driving mechanism can drive the turnover plate FG to turn over between the cover position and the open position.
As shown in fig. 14B, the flipping plate FG is rotatably connected to the fixed base shaft TM1 on the side wall of the dyeing tank, and a mounting hole matched with the fixed base shaft TM1 is formed on the flipping plate FG, and the flipping plate FG can rotate around the fixed base shaft TM1 under the action of the driving mechanism.
Specifically, the driving mechanism comprises a sliding block TM3 capable of sliding along a guide rail TM4, a driving source TM5 for driving a sliding block TM3 to slide along the guide rail TM4, and a connecting rod TM2 with one end hinged with the turnover plate FG and the other end hinged with a sliding block TM 3. The guide rail TM4 extends in the vertical direction, thereby vertically guiding the slider TM 3.
Specifically, the slider TM3 includes a slider body TM32 and a connecting portion TM31 extending from the top of the slider body TM32 to the fixed end of the flip plate FG for being hinged to the connecting rod TM 2.
The driving source may be a cylinder or a linear motor.
Of course, other drive mechanisms may be used to achieve the above-described functions. This is not a limitation of the present application.
As shown in fig. 15, the flipping plate FG includes a cover FG1 capable of covering the dyeing bath and a hinge FG2 extended from the cover FG1 for being hinged to the fixed base shaft TM1, and a mounting hole to be fitted to the fixed base shaft TM1 is provided at the hinge FG 2. The cover FG1 has a flange FG1-2 protruding from the cover body FG1-1 matching the shape of the dye vat slot, the cover body FG1-1 and the flange FG1-2 together forming a vat cavity. To facilitate opening of the flip plate FG, a vent notch FG1-3 for venting air is provided on the flange FG 1-2.
While the invention has been described with reference to specific embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (39)
1. A slide making apparatus, comprising:
the dye tank is provided with a first dye tank and a second dye tank, wherein the first dye tank is used for storing a first dye solution and the second dye tank is used for storing a second dye solution; wherein the content of the first and second substances,
the first dye groove and the second dye groove are both provided with a first basket body which is provided with a plurality of slide inserting positions which are arranged along a second direction different from the first direction and can be inserted with a slide,
the plurality of slide insertion sites of each first basket are in fluid communication with the dye bath in which the first basket is located.
2. The slide preparation device of claim 1, further comprising:
a fixed liquid tank which is arranged along a first direction side by side with the dye tank and is positioned at one side of the dye tank and used for storing fixed liquid,
the fixed liquid groove is internally provided with a second basket body which is provided with a plurality of slide inserting positions which are arranged along the second direction and can be inserted with a slide.
3. The slide preparation device of claim 2, wherein:
the plurality of slide insertion sites of the second basket body include a first type slide insertion site capable of being in fluid communication with the fixed fluid bath and a second type slide insertion site fluidly isolated from the fixed fluid bath.
4. The slide preparation device of claim 2, further comprising:
a cleaning tank which is arranged side by side with the dye liquor tank along a first direction and is positioned at the other side of the dye liquor tank and used for arranging a cleaning box,
the washing box is provided with a plurality of slide inserting positions which are arranged along the second direction and can insert a slide,
the slide insertion sites of the wash cassette are all fluidly isolated from the wash tank.
5. The slide preparation device of claim 2, wherein:
the vat cavities of the first and/or second dye vat and/or the stationary vat comprise a lower cavity below having a first width in the second direction and an upper cavity above having a second width in the second direction greater than the first width,
the upper chamber is in fluid communication with the lower chamber.
6. The slide preparation device of claim 5, wherein:
the first dye trough and/or the second dye trough keep the first basket body in a state that a lower cavity of the trough cavity is used for accommodating the lower part of the first basket body.
7. The slide preparation device of claim 5, wherein:
the upper cavity includes a first portion protruding from the lower cavity in the second direction and a second portion protruding from the lower cavity in a direction opposite to the second direction, and a width of the first portion in the second direction is greater than a width of the first portion in the second direction.
8. The slide preparation device of claim 7, wherein:
the two opposite sides of the first basket body are provided with first lug parts,
and first supporting columns for supporting the first lug parts of the first basket body are respectively arranged on the bottom groove walls of the first part and the second part of the first dye solution groove or the second dye solution groove.
9. The slide preparation device of claim 8, wherein:
the first support column is a cylinder.
10. The slide preparation device of claim 7, wherein: also comprises
A first liquid level limiting column arranged at one of the first part and the second part and used for sucking dyeing liquid in the dyeing liquid groove in a negative pressure mode,
the dye liquor tank can be limited at a first liquid level through a negative pressure suction port of the first liquid level limiting column.
11. The slide preparation device of claim 10, wherein: also comprises
A second liquid level limiting column which is arranged on the other one of the first part and the second part and is provided with an overflow port leading to the outside of the dye liquor groove,
the dye liquor tank can be limited at a second liquid level through an overflow port of the second liquid level limiting column,
the second level is higher than the first level.
12. The slide preparation device of claim 10, wherein:
the slide inserting positions of the first basket body arranged in the first dye groove and the second dye groove keep the slide in a state that the slide printing area is arranged above, the smear area is arranged below and the bottom edge of the printing area is higher than the first liquid level.
13. The slide preparation device of claim 10, wherein the first fluid level limiting post comprises:
a first column having a drain passage with one end in communication with a negative pressure source and the other end in fluid communication with the dye bath.
14. The slide preparation device of claim 13, wherein the first fluid level limiting post further comprises:
a cover having a surrounding wall surrounding a water inlet of the liquid discharge passage of the first cylinder,
the inner wall of the surrounding wall forms a drainage cavity which contains the water inlet of the liquid discharge channel and is opened downwards, and the water inlet of the liquid discharge channel is communicated with the dye liquor groove through the drainage cavity.
15. The slide preparation device of claim 14, wherein:
the bottom surface of the surrounding wall is parallel to the liquid level of the dye liquid stored in the dye liquid groove.
16. The slide preparation device of claim 15, wherein:
the cover body is in threaded connection with the first cylinder, an external thread is arranged on the cylinder part above the water inlet of the liquid drainage channel of the first cylinder, and a counter bore with an internal thread matched with the external thread is arranged on the bottom wall of the drainage cavity.
17. The slide preparation device of claim 13, wherein: the first cylinder is in threaded connection with the dye liquor tank.
18. The slide preparation device of claim 11, wherein:
the second liquid level limiting column comprises an annular wall and an overflow channel which is formed by the inner wall of the annular wall and leads to the outside of the dye liquor tank,
the annular wall is provided with a gap to form the overflow port.
19. The slide preparation device of claim 5, wherein:
the fixed liquid groove keeps the second basket body in a state that the lower cavity of the groove cavity is used for accommodating the lower part of the second basket body.
20. The slide preparation device of claim 7, wherein:
second lugs are arranged on two opposite sides of the second basket body,
and second support columns for supporting second lugs of the second basket body are respectively arranged on the bottom groove walls of the first part and the second part of the fixed liquid groove.
21. A slide preparation device as claimed in claim 20, wherein:
the second support column is a square column body.
22. The slide preparation device of claim 1, wherein: also comprises
And the transfer tank is arranged side by side with the dye tank along a second direction and is positioned on one side of the dye tank and used for caching at least one slide.
23. A slide preparation device as claimed in claim 22, wherein:
the tank cavity of the first dye tank for storing a first dye solution comprises a deep part and a shallow part adjacent to the deep part in a second direction, the deep part has a depth greater than that of the shallow part, and the deep part is in fluid communication with the shallow part,
the first dye solution tank holds the first basket body in a state that the first basket body is accommodated in the deep part.
24. A slide preparation device as claimed in claim 23, wherein:
the shallow portions are provided adjacent to each other on both sides of the deep portion, and a width in the second direction of a first shallow portion adjacent to the intermediate groove is smaller than a width in the second direction of a second shallow portion not adjacent to the intermediate groove.
25. A slide preparation device as claimed in claim 24, wherein:
the structure of the cavity of the second dye liquor tank for storing the second dye liquor is the same as that of the cavity of the first dye liquor tank for storing the first dye liquor.
26. The slide preparation device of claim 22, wherein:
the slide insertion position holds the slide in a state where a width direction of the slide is kept coincident with a first direction,
the transfer slot buffers the slide in a state where a width direction of the slide is kept coincident with a first direction.
27. The slide preparation device of claim 5, wherein:
the lower cavity has a funnel-shaped bottom wall,
the conical tip part of the bottom wall is provided with a liquid outlet.
28. The slide preparation device of claim 5, wherein:
and a liquid inlet capable of injecting liquid into the groove cavity is formed in the conical surface of the bottom wall.
29. A slide preparation device as claimed in claim 28, wherein:
a flow guide column for guiding the liquid injected into the groove cavity is arranged at the liquid inlet,
the flow guide column is provided with a liquid inlet channel which is butted with the liquid inlet and extends along the axial direction of the flow guide column, and a liquid outlet which is communicated with the liquid inlet channel and can lead out the liquid entering the liquid inlet channel to the radial direction of the flow guide column.
30. The slide preparation device of claim 18, further comprising:
and the guide cylinder can be inserted into the overflow channel of the second liquid level limiting column and forms a micro-overflow channel with the channel wall of the overflow channel.
31. A slide preparation device as claimed in claim 30, wherein:
the inside of the guide column body is provided with a vent hole which axially penetrates through the guide column body along the guide column body.
32. The slide preparation device of claim 30, further comprising:
a cover plate capable of covering the first dye solution tank and/or the second dye solution tank and/or the fixed solution tank and having a slide insertion port fitted to the slide insertion site into which a slide is inserted into the slide insertion site,
and the cover plate is provided with a placement hole which corresponds to the position of the second liquid level limiting column and is used for inserting the guide column body into the overflow channel.
33. The slide preparation device of claim 32, wherein the guide cylinder comprises:
a cover portion having a sectional size larger than that of the seating hole, and
and the cross section of the drainage part is smaller than that of the placement hole.
34. The slide preparation device of claim 30, further comprising:
an overflow tank for receiving the staining solution and the fixing solution overflowing from the overflow channel,
and a drainage bulge which can contact with or form a gap with the bottom of the guide column body kept in the overflow channel is arranged at the bottom of the overflow channel.
35. The slide preparation device of claim 1, further comprising
A first cover plate capable of covering the dye bath,
the first cover plate is provided with a slide inserting opening for inserting the slide into the slide inserting position, which is matched with the slide inserting position on the first basket body arranged in the dye solution groove.
36. The slide preparation device of claim 35, further comprising
A flip plate capable of flipping between a covering position covering the slide insertion port on the first cover plate and an opening position opening the slide insertion port on the first cover plate, and
and the driving mechanism can drive the turnover plate to turn over.
37. The slide preparation device of claim 35, further comprising
Sealing rings arranged at the edges of the notches of the first dye solution tank and the second dye solution tank,
the first cover plate is arranged in the dye liquor tank in a mode of pressing the sealing ring to seal the notches of the first dye liquor tank and the second dye liquor tank.
38. The slide preparation device of claim 8, further comprising
A first cover plate capable of covering the dye bath,
a sealing gasket arranged on the surface of the first ear part,
the first cover plate is arranged in the dye solution groove in a mode of pressing the sealing gasket.
39. The slide preparation device of claim 1, wherein:
the slide insertion position holds the slide in a state where the width direction of the slide is kept coincident with the first direction.
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| CN202111661113.2A CN114323882B (en) | 2021-12-31 | 2021-12-31 | Slide glass making device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111661113.2A CN114323882B (en) | 2021-12-31 | 2021-12-31 | Slide glass making device |
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| CN114323882B CN114323882B (en) | 2024-03-29 |
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