CN114286705A - 利用超阈值低频电刺激的神经阻滞 - Google Patents

利用超阈值低频电刺激的神经阻滞 Download PDF

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Publication number
CN114286705A
CN114286705A CN202080061005.9A CN202080061005A CN114286705A CN 114286705 A CN114286705 A CN 114286705A CN 202080061005 A CN202080061005 A CN 202080061005A CN 114286705 A CN114286705 A CN 114286705A
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optionally
minutes
electrical
seconds
nerve
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CN202080061005.9A
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English (en)
Chinese (zh)
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邰常峰
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University of Pittsburgh
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University of Pittsburgh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/36021—External stimulators, e.g. with patch electrodes for treatment of pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36062—Spinal stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36071—Pain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36153—Voltage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/3615—Intensity
    • A61N1/36157—Current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36171—Frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36146—Control systems specified by the stimulation parameters
    • A61N1/36167—Timing, e.g. stimulation onset
    • A61N1/36178—Burst or pulse train parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Electrotherapy Devices (AREA)
CN202080061005.9A 2019-07-03 2020-06-30 利用超阈值低频电刺激的神经阻滞 Pending CN114286705A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962870230P 2019-07-03 2019-07-03
US62/870,230 2019-07-03
PCT/US2020/040288 WO2021003151A1 (en) 2019-07-03 2020-06-30 Neural block by super-threshold low frequency electrical stimulation

Publications (1)

Publication Number Publication Date
CN114286705A true CN114286705A (zh) 2022-04-05

Family

ID=74101293

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080061005.9A Pending CN114286705A (zh) 2019-07-03 2020-06-30 利用超阈值低频电刺激的神经阻滞

Country Status (9)

Country Link
US (1) US20220395686A1 (https=)
EP (1) EP3993865A4 (https=)
JP (1) JP7609359B2 (https=)
KR (1) KR102944729B1 (https=)
CN (1) CN114286705A (https=)
AU (1) AU2020300506B2 (https=)
BR (1) BR112021026805A2 (https=)
CA (1) CA3145807A1 (https=)
WO (1) WO2021003151A1 (https=)

Families Citing this family (4)

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Publication number Priority date Publication date Assignee Title
US11413458B2 (en) 2011-05-19 2022-08-16 Neuros Medical, Inc. Nerve cuff electrode for neuromodulation in large human nerve trunks
EP4103267B1 (en) 2020-02-11 2025-06-04 Neuros Medical, Inc. System for quantifying qualitative patient-reported data sets
JP2024513688A (ja) 2021-03-12 2024-03-27 アンバー セラピューティクス リミテッド 失禁制御のためのデバイス、システム、および方法
AU2022366677A1 (en) * 2021-10-14 2024-04-11 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Sacral neuromodulation for bowel and sexual functions

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US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US20090036945A1 (en) * 2007-08-02 2009-02-05 Chancellor Michael B Methods and systems for achieving a physiological response by pudendal nerve stimulation and blockade
US20090149912A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for electrical modulation of neural conduction
US20100036454A1 (en) * 1998-06-03 2010-02-11 Ndi Medical, Llc. Systems and methods to place one or more leads in muscle for providing electrical stimulation to treat pain
CN102307618A (zh) * 2008-12-09 2012-01-04 内费拉有限公司 泌尿系统的刺激
US20130035740A1 (en) * 2008-11-12 2013-02-07 Endostim, Inc. Device and Implantation System for Electrical Stimulation of Biological Systems
US20150134028A1 (en) * 2013-11-08 2015-05-14 Greatbatch Ltd. Ipg configured to deliver different pulse regimes to different leads for pudendal nerve stimulation
CN105310680A (zh) * 2015-05-14 2016-02-10 南京神桥医疗器械有限公司 一种植入式神经信号阻断装置
CN106621032A (zh) * 2015-10-28 2017-05-10 精能医学股份有限公司 电刺激器及应用其的刺激方法及电刺激系统
CN107073263A (zh) * 2014-09-12 2017-08-18 纽若斯医疗公司 用于大型人类神经干中的神经调控的神经封套电极
US20170348540A1 (en) * 2016-06-02 2017-12-07 Boston Scientific Neuromodulation Corporation Priming-assisted neuromodulation therapy
WO2017210672A1 (en) * 2016-06-03 2017-12-07 The Cleveland Clinic Foundation Systems and methods for monitoring a depth of neuromuscular blockade
WO2018039552A1 (en) * 2016-08-25 2018-03-01 Sharma Virender K System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
CN107949421A (zh) * 2015-05-21 2018-04-20 多伦多大学管理委员会 用于治疗泌尿功能障碍的系统和方法
CN109562255A (zh) * 2016-08-17 2019-04-02 谭佩玲 用于刺激盆底肌肉以治疗和改善功能障碍或紊乱的非侵入性装置和方法及其使用的探针单元

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US6393323B1 (en) * 2000-01-31 2002-05-21 Mcgill University Electronic stimulator implant for modulating and synchronizing bladder and sphincter function
US6928320B2 (en) * 2001-05-17 2005-08-09 Medtronic, Inc. Apparatus for blocking activation of tissue or conduction of action potentials while other tissue is being therapeutically activated
US7328069B2 (en) * 2002-09-06 2008-02-05 Medtronic, Inc. Method, system and device for treating disorders of the pelvic floor by electrical stimulation of and the delivery of drugs to the left and right pudendal nerves
CA2553901C (en) * 2004-01-22 2015-01-20 Rehabtronics Inc. Method of routing electrical current to bodily tissues via implanted passive conductors
US20070073354A1 (en) * 2005-09-26 2007-03-29 Knudson Mark B Neural blocking therapy
US20090254144A1 (en) 2008-04-02 2009-10-08 Case Western Reserve University System and Method of Bladder and Sphincter Control
US9174045B2 (en) * 2009-03-20 2015-11-03 ElectroCore, LLC Non-invasive electrical and magnetic nerve stimulators used to treat overactive bladder and urinary incontinence
US10195434B2 (en) * 2012-06-15 2019-02-05 Case Western Reserve University Treatment of pain using electrical nerve conduction block
WO2015109023A1 (en) 2014-01-17 2015-07-23 Cardiac Pacemakers, Inc. Depletion block to block nerve communication
CN106794347B (zh) 2014-05-23 2020-01-17 电核有限责任公司 用于迷走神经刺激的系统和方法
KR20180034653A (ko) * 2015-08-03 2018-04-04 갈바니 바이오일렉트로닉스 리미티드 신경조절 디바이스
WO2017096007A1 (en) * 2015-12-03 2017-06-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Device and method for nerve block by local cooling to room temperature
DK3405250T3 (da) 2016-01-19 2021-02-15 Incube Labs Llc Systemer til patient-aktiveret blærekontrol

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100036454A1 (en) * 1998-06-03 2010-02-11 Ndi Medical, Llc. Systems and methods to place one or more leads in muscle for providing electrical stimulation to treat pain
US20050070970A1 (en) * 2003-09-29 2005-03-31 Knudson Mark B. Movement disorder stimulation with neural block
US20090036945A1 (en) * 2007-08-02 2009-02-05 Chancellor Michael B Methods and systems for achieving a physiological response by pudendal nerve stimulation and blockade
US20090149912A1 (en) * 2007-12-05 2009-06-11 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Method for electrical modulation of neural conduction
US20130035740A1 (en) * 2008-11-12 2013-02-07 Endostim, Inc. Device and Implantation System for Electrical Stimulation of Biological Systems
CN102307618A (zh) * 2008-12-09 2012-01-04 内费拉有限公司 泌尿系统的刺激
US20150134028A1 (en) * 2013-11-08 2015-05-14 Greatbatch Ltd. Ipg configured to deliver different pulse regimes to different leads for pudendal nerve stimulation
CN107073263A (zh) * 2014-09-12 2017-08-18 纽若斯医疗公司 用于大型人类神经干中的神经调控的神经封套电极
CN105310680A (zh) * 2015-05-14 2016-02-10 南京神桥医疗器械有限公司 一种植入式神经信号阻断装置
CN107949421A (zh) * 2015-05-21 2018-04-20 多伦多大学管理委员会 用于治疗泌尿功能障碍的系统和方法
CN106621032A (zh) * 2015-10-28 2017-05-10 精能医学股份有限公司 电刺激器及应用其的刺激方法及电刺激系统
US20170348540A1 (en) * 2016-06-02 2017-12-07 Boston Scientific Neuromodulation Corporation Priming-assisted neuromodulation therapy
WO2017210672A1 (en) * 2016-06-03 2017-12-07 The Cleveland Clinic Foundation Systems and methods for monitoring a depth of neuromuscular blockade
CN109562255A (zh) * 2016-08-17 2019-04-02 谭佩玲 用于刺激盆底肌肉以治疗和改善功能障碍或紊乱的非侵入性装置和方法及其使用的探针单元
WO2018039552A1 (en) * 2016-08-25 2018-03-01 Sharma Virender K System and method for electrical stimulation of anorectal structures to treat urinary dysfunction
CN109862937A (zh) * 2016-08-25 2019-06-07 维兰德.K.沙马 用于电刺激肛门直肠结构以治疗泌尿功能障碍的系统和方法

Also Published As

Publication number Publication date
WO2021003151A1 (en) 2021-01-07
KR20220035140A (ko) 2022-03-21
KR102944729B1 (ko) 2026-03-30
JP7609359B2 (ja) 2025-01-07
JP2022539172A (ja) 2022-09-07
US20220395686A1 (en) 2022-12-15
EP3993865A1 (en) 2022-05-11
CA3145807A1 (en) 2021-01-07
BR112021026805A2 (pt) 2022-02-15
EP3993865A4 (en) 2023-07-19
AU2020300506A1 (en) 2022-01-27
AU2020300506B2 (en) 2025-09-04

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