CN114272180B - Natural extract for moisturizing skin and inhibiting odor and application thereof - Google Patents

Natural extract for moisturizing skin and inhibiting odor and application thereof Download PDF

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CN114272180B
CN114272180B CN202210091019.6A CN202210091019A CN114272180B CN 114272180 B CN114272180 B CN 114272180B CN 202210091019 A CN202210091019 A CN 202210091019A CN 114272180 B CN114272180 B CN 114272180B
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陈德刚
郑琼璇
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Guangzhou Yuerui Biotechnology Co ltd
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Abstract

The invention discloses a natural extract for moisturizing skin and inhibiting odor and application thereof, wherein raw materials of active ingredients of the natural extract are selected from angelica sinensis, fructus kochiae, white paeony root, motherwort herb, plantain herb, lightyellow sophora root, common cnidium fruit, dandelion and mugwort leaf. The natural extract of some examples of the invention has the effects of sweet and moist, anti-inflammatory, bacteriostasis, antipruritic, smooth muscle and taste inhibition, and blood circulation promoting and pain relieving, and is used for hand sanitizer, bath lotion, hair care, private care and armpit care. The product is used for nursing female private parts, can effectively inhibit peculiar smell and improve the sanitary condition of the private parts. Meanwhile, the product can promote local blood circulation, effectively improve local skin condition and delay aging. When the special nursing agent is used for nursing armpits, the peculiar smell of the armpits can be effectively reduced.

Description

Natural extract for moisturizing skin and inhibiting odor and application thereof
Technical Field
The invention belongs to the field of natural extracts, and particularly relates to a natural extract for moisturizing skin and inhibiting smell and application thereof.
Background
The skin is the largest organ of human body, directly contacts with the external environment, and has the functions of protecting, excreting, regulating body temperature, sensing external stimulus and the like. The health of the skin has a very important influence on the health of humans. The health status of the exposed skin of the face, hands and the like also directly shows the mental state of the person and the look and feel of the other person. It is of interest how to maintain skin health, especially the health of facial skin.
The female private parts are important organs for metabolism and secretion, the female private parts are relatively complex in environment influenced by internal and external factors, are extremely easy to be infected by various germs and cause diseases, not only influence the physical and psychological health and the quality of life of females, but also can cause infertility; meanwhile, the skin at the private part is sensitive, various inflammations or simple skin itch are easy to occur, and special nourishing and nursing are needed. With the improvement of the living standard and health consciousness of people, more and more women begin to pay attention to the maintenance of private parts. The naughty data show that the consumption of the female private care products in 2019 is 12.7% of the world, is a third private care country in the world, which is obtained outside of Japanese and Korean, and the scale of the female private care product market in China is continuously enlarged with the growth of new generation females, and the annual speed is increased by more than 30%.
The natural extract has low irritation and good safety. Many traditional Chinese medicine compositions have the effect of improving skin, but most traditional Chinese medicine compositions are mainly taken orally, and improve skin quality from inside to outside by regulating qi and blood and the like. Although the Chinese herbal medicine has good efficacy, the Chinese herbal medicine has the advantages of slower effect, inconvenient use and difficulty in meeting the fast-paced life of people. More importantly, the oral traditional Chinese medicine composition is difficult to improve local conditions, and is basically ineffective for peculiar smell of private parts. Taking private brand Fuyanjie with higher market share as an example, the washing liquid of the Fuyanjie is a classical Chinese herbal medicine formula which is mixed with collagen, lactobacillus and the like; the patent ingredient KMS formula is added into the ABC nursing foam and nursing lotion. The functional components of the two components contain Chinese herbal medicine extracts, which also shows that the application of the Chinese herbal medicine in private products is accepted and favored by consumers.
Some of the traditional Chinese medicine extracts for external use can improve the skin quality of local skin, but have heavy traditional Chinese medicine flavor, so that the acceptance of people is low. The development of the natural extract which can effectively improve the local skin quality, particularly can effectively inhibit the peculiar smell and is easy to be accepted by people has very practical significance.
Disclosure of Invention
The invention aims to overcome at least one defect of the prior art and provides a natural extract for moisturizing and inhibiting skin and an application thereof.
The technical scheme adopted by the invention is as follows:
in a first aspect of the invention, there is provided:
a natural extract with skin caring and taste inhibiting effects is prepared from radix Angelicae sinensis, kochiae fructus, radix Paeoniae alba, herba Leonuri, herba plantaginis, radix Sophorae Flavescentis, fructus Cnidii, herba Taraxaci and folium Artemisiae Argyi.
In some examples of natural extracts, the active ingredient is an aqueous extract of the raw material.
In some examples of natural extracts, the extraction method of the aqueous extract is a microfluidic method.
In some examples of natural extracts, the raw materials are in the following mass ratios: 2.5 to 3.5 parts of angelica extract, 8 to 12 parts of belvedere fruit extract, 4 to 6 parts of white paeony root extract, 6 to 10 parts of motherwort herb extract, 4.5 to 6 parts of plantain herb extract, 4.5 to 6 parts of lightyellow sophora root extract, 7 to 9 parts of common cnidium fruit extract, 4 to 6 parts of dandelion extract and 4 to 6 parts of mugwort leaf extract.
In a second aspect of the invention, there is provided:
a skin-moistening and smell-suppressing composition comprises auxiliary materials and functional components, wherein the functional components are natural extracts according to the first aspect of the invention.
In some examples of compositions, the adjuvant includes water, glycol, and p-hydroxyacetophenone.
In some examples of compositions, the mass composition is: 30-50% of active ingredient, 20-30% of butanediol, 5-10% of 1, 2-hexanediol, 0.2-1.0% of hydroxyacetophenone and a proper amount of water.
In a third aspect of the invention, there is provided:
a skin care product for moisturizing and inhibiting the odor comprises auxiliary materials and an efficacy composition, wherein the efficacy composition is a natural extract according to the first aspect of the invention or a composition according to the second aspect of the invention.
In some examples of skin care products, the skin care products are used for privacy care, axillary care, hand wash, body wash, hair care.
In some examples of skin care products, the amount of the functional ingredient added is 0.1-5%, preferably 0.5-5%.
The beneficial effects of the invention are as follows:
the natural extract of some examples of the invention has the effects of sweet and moist, anti-inflammatory, antibacterial, antipruritic, smooth muscle and smell inhibiting, blood circulation activating and pain relieving.
The natural extracts of some examples of the present invention are useful in hand washes, body washes, hair care, privacy care, and axillary care.
The natural extract of some examples of the invention is used for nursing female private parts, can effectively inhibit peculiar smell and improve the sanitary condition of the private parts. Meanwhile, the product can promote local blood circulation, effectively improve local skin condition and delay aging. When the special nursing agent is used for nursing armpits, the peculiar smell of the armpits can be effectively reduced.
The natural extract of some examples of the present invention is mild in nature, has substantially no irritation to skin, and can be used for daily care of private parts.
Detailed Description
The face is deprived of qi and blood and moistened, turbid qi stays and forms chloasma, which is often seen in women of childbearing age.
In the recipe, dang Gui and Paeonia lactiflora are monarch, dang Gui is sweet in nature, pungent and warm in nature, and enter liver, heart and spleen meridians. Promoting blood circulation, replenishing blood, improving blood circulation, and has good SOD activity. Shao is bitter in flavor, sour, qi-balancing, slightly cold, entering liver meridian and spleen meridian. The main function is antibacterial agent, humectant and paeoniflorin as effective component, and has inhibiting effect on some pathogenic bacteria and fungi.
Herba plantaginis, fructus Cnidii and folium Artemisiae Argyi are ministerial drugs, and herba plantaginis has sweet and cold taste, wherein the dent SL is a natural antibiotic, and contains various natural antibacterial and antiinflammatory components, which can prevent human body inflammation and enhance organism antiviral ability. In addition, has obvious diuretic effect and certain curative effect on skin eczema. Fructus Cnidii has Wen Wei bitter properties, and has antiinflammatory and antifungal effects. Has good efficacy on acute exudative dermatosis, such as: eczema of vulva, pruritus vulvae of women, trichomonas vaginitis, and the like; while nourishing the skin. The mugwort leaf has bitter, pungent and warm taste and has the effects of warming channel, removing dampness, dispelling cold, stopping bleeding, diminishing inflammation, resisting allergy and the like. It is one of the common herbs for gynecology, especially for deficiency-cold gynecology.
Kochiae fructus, motherwort herb and kuh-seng are used as adjuvants, and the Kochiae fructus has the main functions of clearing heat and promoting diuresis, dispelling wind and relieving itching, is used for treating pudendum itch and leukorrhagia, rubella, eczema, skin itch and the like, and the triterpene saponin contained in the Kochiae fructus is used as a main bioactive component, and has remarkable anti-inflammatory and antibacterial pharmacological effects. Herba Leonuri is bitter, pungent and slightly cold, has effects of promoting blood circulation, regulating menstruation, inducing diuresis, relieving swelling, clearing heat, detoxicating, inhibiting bacteria, and relieving inflammation, and is one of the main traditional Chinese medicines for treating gynecological diseases in the past, and the whole herb is mainly used as medicine. The kuh-seng has bitter taste and cold property, contains matrine, cytisine and the like, and has the effects of clearing heat and promoting diuresis, resisting bacteria and diminishing inflammation and resisting allergy.
Dandelion is sweet, slightly bitter and cold in taste, has the effects of clearing heat and removing toxicity, eliminating carbuncles and resolving hard mass, and has a certain inhibition effect on staphylococcus aureus. The health and nutrition components contained in the plant body, such as protein, microelements, carbohydrate, vitamins, etc., are one of the herbal medicines for maintaining beauty and keeping young.
The ingredients are synergistic, and the effects of activating blood, nourishing skin, inhibiting bacteria, killing bacteria and moistening skin are achieved.
Angelica sinensis is the dry root of Angelica sinensis Angelica sinensis (Oliv.) Diels, umbelliferae. Sweet, pungent and warm. Replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, and loosening bowel to relieve constipation.
Fructus Kochiae is a dried mature fruit of Kochia scoparia (L.) Schrad. Pungent, bitter and cold. Clear heat and promote diuresis, dispel wind and relieve itching.
Radix Paeoniae alba is dry root of Pall Paeonia lactiflora of Pall of Ranunculaceae. Bitter, sour and slightly cold. Calm liver and relieve pain, nourish blood and regulate menstruation, astringe yin and stop sweating.
Herba Leonuri is fresh or dry aerial part of herba Leonuri Leonurus japonicus Houtt of Labiatae. Bitter and pungent, and slightly cold. Promoting blood circulation, regulating menstruation, inducing diuresis and relieving swelling.
The herba plantaginis is dried whole herb of herba plantaginis Plantago asiatica L of Plantaginaceae or Plantago depressa Willd of Plantago asiatica. Sweet and cold. Clear heat and induce diuresis, eliminate phlegm, cool blood and detoxify.
The radix Sophorae Flavescentis is dry root of radix Sophorae Flavescentis Sophora flavescens Ait. Bitter and cold. Clear heat and dry dampness, kill parasites and induce diuresis.
Fructus Cnidii is a dry mature fruit of Cnidium monnieri (L.) Cuss. Pungent, bitter and warm; it is slightly toxic. Warming kidney, strengthening yang, eliminating dampness, dispelling wind and killing parasites.
Herba Taraxaci is dried whole herb of Taraxacum officinale Taraxacum mongolicum Hand-mazz. And Taraxacum officinale Taraxacum sinicum Kitag or plants of the same genus. Bitter, sweet and cold. Clearing away heat and toxic materials, relieving swelling, resolving hard mass, promoting urination, and treating stranguria.
The mugwort leaf is a dried leaf of Artemisia argyi Levi et Vant. Pungent, bitter and warm; it is slightly toxic. Dispel cold and alleviate pain, warm meridians and stop bleeding.
The technical scheme of the invention is further described below by combining examples.
In the following examples, each active ingredient of the natural extract is extracted by a micro-jet method, the solvent used in the extraction by the micro-jet method is water, the extraction temperature is between 15 and 40 ℃, the natural extract is concentrated to a specific gravity of about 1.1, and the parts are parts by mass unless specified otherwise.
Example 1:
the active ingredients of the natural extract are prepared from the following raw materials in percentage by weight:
Figure SMS_1
example 2:
the active ingredients of the natural extract are prepared from the following raw materials in percentage by weight:
Figure SMS_2
example 3:
the active ingredients of the natural extract are prepared from the following raw materials in percentage by weight:
Figure SMS_3
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example 4:
the active ingredients of the natural extract are prepared from the following raw materials in percentage by weight:
Figure SMS_4
Figure SMS_5
preparation of skin-moisturizing and taste-inhibiting composition:
the natural extracts of examples 1-4 are respectively taken and mixed according to the proportion of 30-50% of natural extract, 20-30% of butanediol, 5-10% of 1,2 hexanediol, 0.2-1.0% of hydroxyacetophenone and a proper amount of water to obtain the skin-moistening and taste-inhibiting composition
Comparative example 1:
the active ingredients of the natural extract are prepared from the following raw materials in percentage by weight:
kochia scoparia L.8 parts
White peony root 8 parts
10 parts of motherwort
5 parts of plantain herb
Radix Sophorae Flavescentis 6 parts
Fructus Cnidii 7 parts
Dandelion 5 parts
5 parts of mugwort leaf.
Comparative example 2:
the active ingredients of the natural extract are prepared from the following raw materials in percentage by weight:
3 parts of Chinese angelica
Kochia scoparia L.8 parts
White peony root 5 parts
10 parts of motherwort
5 parts of plantain herb
Radix Sophorae Flavescentis 2 parts
Fructus cnidii 11 parts
Dandelion 5 parts
5 parts of mugwort leaf.
In vitro bacteriostasis experiment:
the bacteriostatic ability of the natural extract was tested by using a drug sensitive paper sheet method. The natural extract of example 2 was adsorbed in different concentrations using a drug sensitive paper sheet having a diameter of 5mm. 100 mu L of different strains are coated on LB culture medium, paper sheets are stuck on the surface of the culture medium after the surface of the culture medium is dried, the diameter of a bacteria inhibition ring is observed and measured after the culture is carried out for 24 hours at 37 ℃, and the culture is repeated for 3 times, and blank paper sheets are used as blank control. The experimental results are shown in table 1.
TABLE 1 average inhibition zone diameter for Natural extracts of different concentrations of EXAMPLE 2
0.1mg/mL 0.2mg/mL 0.4mg/mL Blank control
Coli bacterium 6.23 7.41 9.26 5.00
Staphylococcus aureus 7.36 8.55 9.53 5.00
Shigella dysenteriae 6.17 7.24 9.11 5.00
Pseudomonas aeruginosa 8.10 9.66 10.13 5.00
Typhimurium salve door 6.18 7.27 9.16 5.00
From the data in Table 1, the natural extract of the present invention has a good bacteriostatic ability against various bacteria.
Skin-moistening and smell-suppressing lotion:
the natural extracts prepared in example 2 and comparative example 1 were prepared into lotions by adding water and a suitable amount of hydroxyacetophenone as preservative and adjusting the pH to about 4.0, and the concentrations of the natural extracts were 5%, which were respectively designated as skin-moistening and odor-suppressing lotions A, B.
Skin-moistening and smell-suppressing cream:
the natural extracts prepared in example 2 and comparative example 2 are added with water and a proper amount of hydroxyacetophenone as preservative, and the thickening agent is prepared into cream, wherein the addition amount of the natural extracts is 2%, and the addition amount of butanediol is 1% and 1,2 hexanediol is 0.5%. Are respectively marked as skin-moistening and smell-suppressing pastes G1 and G2.
The technical scheme of the invention is further described below in conjunction with experiments.
Female privacy:
female volunteers 60 persons have normal menstrual cycle and no skin injury, and are divided into 2 groups (experimental group and control group) on average at random, 30 persons in each group respectively use skin-moistening and smell-suppressing lotion A, B for private part cleaning. The using method comprises the following steps: outside menstrual period, the private parts are normally washed by clear water, 10mL of washing liquid is taken, warm boiled water with the temperature of about 30-45 ℃ is added to be mixed to 100mL, the vulva is scrubbed, the vagina is flushed, and the vagina is continuously used for 2 weeks. The results of the self-evaluation of the effect of use are shown in Table 2.
TABLE 2 statistical Table of skin-moisturizing and taste-suppressing lotion effects
Figure SMS_6
Note that: the irritation sensation of the application was self-assessed at 3 rd application and compared to that of the application prior to application.
From the data in Table 2, the natural extract of example 2 has better effect and can moisten skin and inhibit taste.
Underarm taste inhibition test:
volunteers with secretion under the self-sensory axilla were selected, of which 60 female volunteers were equally divided into 2 groups (experimental group 1, control group 1), 30 persons each; male volunteers 80 were equally divided into 2 groups (experimental group 2, control group 2), 40 per group. The experimental group used emollient and smell suppressing cream G1, and the control group used emollient and smell suppressing cream G2. The preparation is applied to the armpits in the morning and evening for 15 days, and is self-evaluated on the 15 th day. The results are shown in Table 3:
TABLE 3 results of underarm odor inhibition test
Evaluation index Experiment group 1 Control group 1 Experiment group 2 Control group 2
Has irritation 0 2 1 2
No irritation 30 28 39 38
Reduction of secretion volume 23 18 33 27
Constant secretion amount 7 12 7 13
Increased secretion volume 0 0 0 0
Odor mitigation 25 19 34 28
No peculiar smell change 5 11 6 12
Aggravate the bad smell 0 0 0 0
From the data in Table 3, it is clear that the skin-moisturizing and odor-suppressing cream G1 is substantially non-irritating and can effectively suppress underarm odor and reduce secretions.
The above description of the present invention is further illustrated in detail and should not be taken as limiting the practice of the present invention. It is within the scope of the present invention for those skilled in the art to make simple deductions or substitutions without departing from the concept of the present invention.

Claims (7)

1. A natural extract for moisturizing and inhibiting the taste, which is characterized in that: the active ingredients of the traditional Chinese medicine comprise the raw materials of angelica sinensis, fructus kochiae, white paeony root, motherwort herb, plantain herb, lightyellow sophora root, common cnidium fruit, dandelion and mugwort leaf, wherein the active ingredients are water extracts of the raw materials, the extraction method of the water extracts is a micro-jet method, and the active ingredients are prepared from the following components in parts by mass: 2.5 to 3.5 parts of angelica extract, 8 to 12 parts of belvedere fruit extract, 4 to 6 parts of white paeony root extract, 6 to 10 parts of motherwort herb extract, 4.5 to 6 parts of plantain herb extract, 4.5 to 6 parts of lightyellow sophora root extract, 7 to 9 parts of common cnidium fruit extract, 4 to 6 parts of dandelion extract and 4 to 6 parts of mugwort leaf extract.
2. A skin-moistening and smell-suppressing composition comprises auxiliary materials and functional components, and is characterized in that: the functional component is the natural extract of claim 1.
3. The composition of claim 2, wherein: the auxiliary materials comprise water, glycol and p-hydroxyacetophenone.
4. A composition according to claim 3, characterized in that: the mass composition of the material is as follows: 30-50% of effective components, 20-30% of butanediol, 5-10% of 1, 2-hexanediol and 0.2-1.0% of hydroxyacetophenone, and a proper amount of water.
5. A skin care product for moisturizing and inhibiting the smell comprises auxiliary materials and an efficacy composition, and is characterized in that: the efficacy composition is the natural extract of claim 1.
6. The skin care product according to claim 5, wherein: the skin care product is used for private care, armpit care, hand sanitizer, bath foam and hair care.
7. A skin care product according to claim 5 or 6, characterized in that: the addition amount of the efficacy composition is 0.1-5%.
CN202210091019.6A 2022-01-26 2022-01-26 Natural extract for moisturizing skin and inhibiting odor and application thereof Active CN114272180B (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1079910A (en) * 1992-06-08 1993-12-29 万秀喜 Feminine napkins farourable to orotection of menstrual period
CN102579602A (en) * 2012-03-06 2012-07-18 徐金红 Medicinal composition for treating eczema
CN111437225A (en) * 2020-04-23 2020-07-24 广东正汇源实业有限公司 Hemostatic, granulation-promoting and antibacterial composition and application thereof
CN211095311U (en) * 2019-10-26 2020-07-28 佛山市嘉博卫生用品科技有限公司 Traditional Chinese medicine bacteriostatic sanitary towel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1079910A (en) * 1992-06-08 1993-12-29 万秀喜 Feminine napkins farourable to orotection of menstrual period
CN102579602A (en) * 2012-03-06 2012-07-18 徐金红 Medicinal composition for treating eczema
CN211095311U (en) * 2019-10-26 2020-07-28 佛山市嘉博卫生用品科技有限公司 Traditional Chinese medicine bacteriostatic sanitary towel
CN111437225A (en) * 2020-04-23 2020-07-24 广东正汇源实业有限公司 Hemostatic, granulation-promoting and antibacterial composition and application thereof

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