CN114272165A - Whitening and firming plant essence skin care emulsion and preparation method thereof - Google Patents
Whitening and firming plant essence skin care emulsion and preparation method thereof Download PDFInfo
- Publication number
- CN114272165A CN114272165A CN202210026628.3A CN202210026628A CN114272165A CN 114272165 A CN114272165 A CN 114272165A CN 202210026628 A CN202210026628 A CN 202210026628A CN 114272165 A CN114272165 A CN 114272165A
- Authority
- CN
- China
- Prior art keywords
- whitening
- kenaf
- skin care
- extract
- emulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000839 emulsion Substances 0.000 title claims abstract description 73
- 230000002087 whitening effect Effects 0.000 title claims abstract description 58
- 238000002360 preparation method Methods 0.000 title claims description 16
- 238000004945 emulsification Methods 0.000 title description 4
- 240000000797 Hibiscus cannabinus Species 0.000 claims abstract description 72
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 48
- 239000000284 extract Substances 0.000 claims abstract description 48
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 46
- 241000196324 Embryophyta Species 0.000 claims abstract description 40
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 36
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 claims abstract description 31
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 28
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 claims abstract description 22
- 229940032094 squalane Drugs 0.000 claims abstract description 22
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 claims abstract description 16
- 229940119170 jojoba wax Drugs 0.000 claims abstract description 15
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 claims abstract description 15
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 claims abstract description 15
- 229960002216 methylparaben Drugs 0.000 claims abstract description 15
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229920000223 polyglycerol Polymers 0.000 claims abstract description 15
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 14
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims abstract description 14
- 229920000057 Mannan Polymers 0.000 claims abstract description 14
- 229960000458 allantoin Drugs 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 14
- 229940042585 tocopherol acetate Drugs 0.000 claims abstract description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 42
- 229920002749 Bacterial cellulose Polymers 0.000 claims description 37
- 239000005016 bacterial cellulose Substances 0.000 claims description 37
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 21
- 239000000843 powder Substances 0.000 claims description 18
- 238000003756 stirring Methods 0.000 claims description 17
- 238000001816 cooling Methods 0.000 claims description 14
- 238000001914 filtration Methods 0.000 claims description 14
- 238000005303 weighing Methods 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 11
- 239000007787 solid Substances 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 9
- 241000218236 Cannabis Species 0.000 claims description 8
- 229910021529 ammonia Inorganic materials 0.000 claims description 8
- 238000004140 cleaning Methods 0.000 claims description 8
- 239000000706 filtrate Substances 0.000 claims description 8
- 238000004108 freeze drying Methods 0.000 claims description 8
- 238000005194 fractionation Methods 0.000 claims description 7
- 238000000227 grinding Methods 0.000 claims description 7
- 238000010438 heat treatment Methods 0.000 claims description 7
- 230000002829 reductive effect Effects 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims description 7
- 229960005150 glycerol Drugs 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 229940114926 stearate Drugs 0.000 claims description 4
- 239000006210 lotion Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 abstract description 17
- 206010070834 Sensitisation Diseases 0.000 abstract description 2
- 230000008313 sensitization Effects 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 49
- 239000000243 solution Substances 0.000 description 22
- 235000019441 ethanol Nutrition 0.000 description 19
- 239000000047 product Substances 0.000 description 13
- 238000012360 testing method Methods 0.000 description 12
- 230000000052 comparative effect Effects 0.000 description 9
- 239000000835 fiber Substances 0.000 description 9
- 239000000523 sample Substances 0.000 description 9
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 8
- 230000003647 oxidation Effects 0.000 description 8
- 238000007254 oxidation reaction Methods 0.000 description 8
- 102000003425 Tyrosinase Human genes 0.000 description 7
- 108060008724 Tyrosinase Proteins 0.000 description 7
- 239000002537 cosmetic Substances 0.000 description 7
- -1 flavonoid compound Chemical class 0.000 description 7
- 238000003860 storage Methods 0.000 description 7
- 230000002209 hydrophobic effect Effects 0.000 description 6
- 150000002989 phenols Chemical class 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 5
- 230000032683 aging Effects 0.000 description 5
- 229930003935 flavonoid Natural products 0.000 description 5
- 235000017173 flavonoids Nutrition 0.000 description 5
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 5
- 238000013112 stability test Methods 0.000 description 5
- LFTLOKWAGJYHHR-UHFFFAOYSA-N N-methylmorpholine N-oxide Chemical compound CN1(=O)CCOCC1 LFTLOKWAGJYHHR-UHFFFAOYSA-N 0.000 description 4
- 125000003118 aryl group Chemical group 0.000 description 4
- 239000002131 composite material Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000006911 enzymatic reaction Methods 0.000 description 4
- 150000004676 glycans Chemical class 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 230000005764 inhibitory process Effects 0.000 description 4
- 230000003993 interaction Effects 0.000 description 4
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000003020 moisturizing effect Effects 0.000 description 4
- 235000013824 polyphenols Nutrition 0.000 description 4
- 229920001282 polysaccharide Polymers 0.000 description 4
- 239000005017 polysaccharide Substances 0.000 description 4
- 238000001556 precipitation Methods 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 3
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 238000007605 air drying Methods 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- MGJZITXUQXWAKY-UHFFFAOYSA-N diphenyl-(2,4,6-trinitrophenyl)iminoazanium Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1N=[N+](C=1C=CC=CC=1)C1=CC=CC=C1 MGJZITXUQXWAKY-UHFFFAOYSA-N 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 230000008099 melanin synthesis Effects 0.000 description 3
- 235000005152 nicotinamide Nutrition 0.000 description 3
- 239000011570 nicotinamide Substances 0.000 description 3
- 229960003966 nicotinamide Drugs 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- 230000035699 permeability Effects 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- ZNCXUFVDFVBRDO-UHFFFAOYSA-N pyridine;sulfuric acid Chemical compound [H+].[O-]S([O-])(=O)=O.C1=CC=[NH+]C=C1 ZNCXUFVDFVBRDO-UHFFFAOYSA-N 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 2
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 2
- UBSCDKPKWHYZNX-UHFFFAOYSA-N Demethoxycapillarisin Natural products C1=CC(O)=CC=C1OC1=CC(=O)C2=C(O)C=C(O)C=C2O1 UBSCDKPKWHYZNX-UHFFFAOYSA-N 0.000 description 2
- 244000303040 Glycyrrhiza glabra Species 0.000 description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 2
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 230000002292 Radical scavenging effect Effects 0.000 description 2
- 206010040844 Skin exfoliation Diseases 0.000 description 2
- 230000003796 beauty Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 2
- 235000005487 catechin Nutrition 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229940074393 chlorogenic acid Drugs 0.000 description 2
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 2
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 2
- 235000001368 chlorogenic acid Nutrition 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 229950001002 cianidanol Drugs 0.000 description 2
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 2
- CBMPTFJVXNIWHP-UHFFFAOYSA-L disodium;hydrogen phosphate;2-hydroxypropane-1,2,3-tricarboxylic acid Chemical compound [Na+].[Na+].OP([O-])([O-])=O.OC(=O)CC(O)(C(O)=O)CC(O)=O CBMPTFJVXNIWHP-UHFFFAOYSA-L 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- HHEAADYXPMHMCT-UHFFFAOYSA-N dpph Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1[N]N(C=1C=CC=CC=1)C1=CC=CC=C1 HHEAADYXPMHMCT-UHFFFAOYSA-N 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- HGEMCUOAMCILCP-UHFFFAOYSA-N isotridecane Natural products CCCCCCCCCCC(C)C HGEMCUOAMCILCP-UHFFFAOYSA-N 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- 235000008777 kaempferol Nutrition 0.000 description 2
- 210000002510 keratinocyte Anatomy 0.000 description 2
- 235000011477 liquorice Nutrition 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- UXOUKMQIEVGVLY-UHFFFAOYSA-N morin Natural products OC1=CC(O)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UXOUKMQIEVGVLY-UHFFFAOYSA-N 0.000 description 2
- 239000004006 olive oil Substances 0.000 description 2
- 235000008390 olive oil Nutrition 0.000 description 2
- 229930000223 plant secondary metabolite Natural products 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 150000003254 radicals Chemical class 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000000434 stratum corneum Anatomy 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 description 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 1
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 description 1
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 description 1
- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 244000283763 Acetobacter aceti Species 0.000 description 1
- 235000007847 Acetobacter aceti Nutrition 0.000 description 1
- 241000205585 Aquilegia canadensis Species 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000202726 Bupleurum Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- 235000012766 Cannabis sativa ssp. sativa var. sativa Nutrition 0.000 description 1
- 235000012765 Cannabis sativa ssp. sativa var. spontanea Nutrition 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 244000020518 Carthamus tinctorius Species 0.000 description 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 description 1
- 101100081581 Chlamydomonas reinhardtii ODA1 gene Proteins 0.000 description 1
- 101100224940 Chlamydomonas reinhardtii ODA2 gene Proteins 0.000 description 1
- 241000251730 Chondrichthyes Species 0.000 description 1
- 240000006766 Cornus mas Species 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 108010082495 Dietary Plant Proteins Proteins 0.000 description 1
- AFSDNFLWKVMVRB-UHFFFAOYSA-N Ellagic acid Chemical compound OC1=C(O)C(OC2=O)=C3C4=C2C=C(O)C(O)=C4OC(=O)C3=C1 AFSDNFLWKVMVRB-UHFFFAOYSA-N 0.000 description 1
- ATJXMQHAMYVHRX-CPCISQLKSA-N Ellagic acid Natural products OC1=C(O)[C@H]2OC(=O)c3cc(O)c(O)c4OC(=O)C(=C1)[C@H]2c34 ATJXMQHAMYVHRX-CPCISQLKSA-N 0.000 description 1
- 229920002079 Ellagic acid Polymers 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 description 1
- 241000218033 Hibiscus Species 0.000 description 1
- 235000005206 Hibiscus Nutrition 0.000 description 1
- 235000007185 Hibiscus lunariifolius Nutrition 0.000 description 1
- 244000130592 Hibiscus syriacus Species 0.000 description 1
- 235000018081 Hibiscus syriacus Nutrition 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- WTDRDQBEARUVNC-LURJTMIESA-N L-DOPA Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-LURJTMIESA-N 0.000 description 1
- WTDRDQBEARUVNC-UHFFFAOYSA-N L-Dopa Natural products OC(=O)C(N)CC1=CC=C(O)C(O)=C1 WTDRDQBEARUVNC-UHFFFAOYSA-N 0.000 description 1
- 244000208060 Lawsonia inermis Species 0.000 description 1
- 241000229179 Ledebouriella Species 0.000 description 1
- 240000004658 Medicago sativa Species 0.000 description 1
- 235000017587 Medicago sativa ssp. sativa Nutrition 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- 244000170916 Paeonia officinalis Species 0.000 description 1
- 235000006484 Paeonia officinalis Nutrition 0.000 description 1
- 235000019774 Rice Bran oil Nutrition 0.000 description 1
- 241000220317 Rosa Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 241000207929 Scutellaria Species 0.000 description 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 206010052428 Wound Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 244000089698 Zanthoxylum simulans Species 0.000 description 1
- 238000002835 absorbance Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 239000003225 biodiesel Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 235000009120 camo Nutrition 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 235000005607 chanvre indien Nutrition 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 229960002852 ellagic acid Drugs 0.000 description 1
- 235000004132 ellagic acid Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000004299 exfoliation Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000005714 functional activity Effects 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- 229940072008 glycyrrhiza glabra extract Drugs 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 239000011487 hemp Substances 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 229920002674 hyaluronan Polymers 0.000 description 1
- 229960003160 hyaluronic acid Drugs 0.000 description 1
- 238000005984 hydrogenation reaction Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 229960004502 levodopa Drugs 0.000 description 1
- 229940069445 licorice extract Drugs 0.000 description 1
- 230000031700 light absorption Effects 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000010687 lubricating oil Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- FAARLWTXUUQFSN-UHFFFAOYSA-N methylellagic acid Natural products O1C(=O)C2=CC(O)=C(O)C3=C2C2=C1C(OC)=C(O)C=C2C(=O)O3 FAARLWTXUUQFSN-UHFFFAOYSA-N 0.000 description 1
- BEGLCMHJXHIJLR-UHFFFAOYSA-N methylisothiazolinone Chemical compound CN1SC=CC1=O BEGLCMHJXHIJLR-UHFFFAOYSA-N 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000002086 nanomaterial Substances 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 230000005693 optoelectronics Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 230000036961 partial effect Effects 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000008104 plant cellulose Substances 0.000 description 1
- 239000003910 polypeptide antibiotic agent Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009323 psychological health Effects 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 230000003716 rejuvenation Effects 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000008165 rice bran oil Substances 0.000 description 1
- 239000008132 rose water Substances 0.000 description 1
- 229940109850 royal jelly Drugs 0.000 description 1
- 239000012488 sample solution Substances 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000010686 shark liver oil Substances 0.000 description 1
- 229940069764 shark liver oil Drugs 0.000 description 1
- 230000005808 skin problem Effects 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 229940031439 squalene Drugs 0.000 description 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000000967 suction filtration Methods 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000019160 vitamin B3 Nutrition 0.000 description 1
- 239000011708 vitamin B3 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 238000001238 wet grinding Methods 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
The invention discloses a whitening and firming plant essence skin care emulsion which comprises the following raw materials: 2-4% of jojoba oil, 1.5-2% of squalane, 0.35-0.5% of nicotinamide, 0.5-1% of polyglycerol stearate, 1.5-2% of tocopherol acetate, 10-12% of glycerol, 0.05-0.1% of methyl paraben, 0.2-0.3% of allantoin, 0.2-0.5% of mannan, 3-5% of kenaf extract and the balance of water. The prepared emulsion has good whitening and tightening effects and is mainly prepared from a pure natural plant formula; the emulsion has uniform texture and better stability; low sensitization and wide audience range.
Description
Technical Field
The invention relates to the technical field of daily chemical products, in particular to a whitening and firming plant essence skin care emulsion and a preparation method thereof.
Background
The skin care product is a daily chemical product for cleaning, repairing, beautifying and maintaining the body surface of people in an external use mode, and can help to protect, repair and improve the using state, thereby fully showing the beauty of the human body and being beneficial to the physical and psychological health of people. Along with the improvement of living standard of people, the status and the importance of skin care products in daily life of people are increasingly improved, especially in recent years, the living rhythm of people is accelerated, the mental stress is higher, the skin condition is worse and worse, and the attention degree to the skin is gradually increased. However, part of emulsion skin care products sold in the current market have the phenomenon that the content of heavy metal components such as lead and mercury exceeds the standard, although the skin care products are not dangerous to life in a short time, the skin can be seriously aged after long-term use, and the body health is influenced, so that the safe pure natural plant skin care products can quickly return.
In ancient times, people began to wipe their face and care their skin with plant juices to keep the skin fine and tender, some had safflower as blush, and some had henna to wash their hair, which was the beginning of natural cosmetics. Ming Dynasty Li Shizhen listed as a facial herb in Ben Cao gang mu, and generalizes the traditional Chinese medicines for skin care in the past generations of herbs. The repeated research of Chinese traditional medicine in skin care prescription in the classic works of Chijin Fang of Chinese medicine by foreign researchers finds that the traditional Chinese medicines such as Sichuan peony root, ledebouriella root, bupleurum root, etc. have obvious effect of resisting tyrosinase inhibition. And the modern main application scientific technology is used for reasonably proportioning and selecting natural herbal plants, extracting and purifying medicinal components and the like, so that the effectiveness and safety of the medicine are ensured.
The plant contains various skin-care nutrient components, wherein the polysaccharide has various pharmacological actions such as oxidation resistance, tumor resistance, aging resistance, inflammation resistance and the like, and a large number of hydrophilic warp groups in the structure make the polysaccharide have better water absorption, shaving performance, emulsification performance, film forming performance and the like when the polysaccharide is externally used, and the polysaccharide can generate the effects of moisturizing, repairing damaged skin, oxidation resistance, aging resistance and the like when being applied to cosmetics. The flavonoids are natural phenolic compounds with special structures, exist in free states or glycosides in plants, and have the effects of whitening, resisting oxidation, resisting inflammation, inhibiting bacteria, preventing sunlight and the like. The flavonoid compound can effectively inhibit tyrosinase activity, thereby slowing down melanin formation. Part of the flavonoid compounds contain a large amount of phenolic hydroxyl groups with reducibility and hydrophilicity, so that the flavonoid compounds can eliminate free radicals, thereby delaying aging. In addition, the flavonoid compound can reduce the expression level of inflammatory mediators and has effective anti-inflammation; can crack the microbial cell membrane to improve the permeability of the cell membrane and kill the microbe; can effectively absorb ultraviolet light and has good sun-screening effect. The organic acid is an acidic compound and has the functions of bacteriostasis, whitening, antioxidation and the like. The exertion of the bacteriostasis of the organic acid is related to the bacteriostasis mechanisms of destroying the structural integrity of the membrane, competing with the energy of microorganisms, preventing the synthesis of macromolecules, increasing the intracellular osmotic pressure, inducing the expression of host cell antibacterial peptide and the like. The organic acid can also effectively inhibit the activity of melanin synthesis related enzyme and play a role in whitening; free radicals can be bound to block or slow down the progress of the oxidation process.
Chinese patent CN 105193882A discloses a kenaf extract, a cosmetic composition thereof and an application thereof, wherein kenaf roots are extracted by 85-95% ethanol, and the obtained kenaf extract is applied to cosmetics and medicines, but related researches on kenaf leaves are not described.
Chinese patent CN 107184528A discloses a whitening emulsion and a preparation method thereof; the whitening emulsion is prepared from the following raw materials: licorice extract, herb of Chinese prickly ash, rose water, royal jelly, olive oil and deionized water; according to the invention, the compatibility of the liquorice and the Chinese herbal medicines with skin whitening and caring functions enhances the respective effects of the liquorice and the Chinese herbal medicines, so that the whitening effect is enhanced; the raw materials are natural components without irritation, so that the whitening and moisturizing effects can be achieved, no irritation is caused to skin, and the skin-care cream can be used for a long time; the preparation process is simple to operate, has low requirements on equipment, and reduces the production cost while ensuring the production quality.
CN 106726763 a discloses a whitening emulsion and a preparation method thereof, wherein the whitening emulsion comprises the following components in percentage by weight: 6-12% of 20-hydroxyecdysterone, 5-10% of dipotassium glycyrrhizinate, 2-6% of vitamin C, 2-4% of glycerol, 1-5% of ellagic acid, 2-6% of hyaluronic acid, 1-2% of beeswax, 1-2% of sodium alginate, 0.1-0.5% of citric acid, 0.1-0.5% of methylisothiazolinone and 50-79.8% of water. The whitening emulsion provided by the invention can effectively improve darkness, spots and aging resistance, block melanin production, increase skin moistening degree and lubricity, has a good whitening effect, and is safe and non-irritant. However, in the prior art, the whitening emulsion emphasizes that the stability, uniformity and texture of the emulsion are poor due to no addition of natural plant ingredients, so that the preparation of the skin care emulsion with natural ingredients, good whitening effect and firming effect, uniform texture and good stability is particularly important.
Disclosure of Invention
In order to solve the technical problems, the invention provides a whitening and firming plant essence skin care emulsion and a preparation method thereof, and the technical scheme is as follows:
a whitening and firming plant essence skin care emulsion comprises the following raw materials: 2-4% of jojoba oil, 1.5-2% of squalane, 0.35-0.5% of nicotinamide, 0.5-1% of polyglycerol stearate, 1.5-2% of tocopherol acetate, 10-12% of glycerol, 0.05-0.1% of methyl paraben, 0.2-0.3% of allantoin, 0.2-0.5% of mannan and the balance of water.
Nicotinamide, also known as nicotinamide, 3-pyridinecarboxamide, is an amide compound of nicotinic acid and is also a derivative of vitamin B3. Is a white crystalline powder, slightly or almost odorless, bitter, and is vitamin PP, which belongs to azacyclo-pyridine derivatives. It is easily soluble in water or ethanol, and soluble in glycerol. The whitening mechanism of niacinamide comprises three aspects: (1) inhibiting the formation of melanin granules; (2) inhibiting the transfer of melanin to keratinocytes; (3) accelerate the transfer of melanin to the stratum corneum in keratinocytes and promote stratum corneum exfoliation.
Squalane, also known as deep-sea shark liver oil, squalane, isotridecane. Originally, squalane was obtained by hydrogenation of squalene extracted from the liver of deep-sea sharks by scientists. However, it has recently been found that squalane can be extracted in small amounts from olive oil, rice bran oil, wheat germ oil, yeast, and the like. Squalane is a kind of grease most similar to human sebum, has high-efficiency oxygen carrying performance, can be integrated with human sebum after being used, forms a protective film with good permeability on the surface layer of skin, enables the skin to successfully metabolize water and air, can prevent water loss and nourish the skin, and is not greasy. The squalane maintains the balance between skin and sebum, can improve the moisture and other nutrition absorption capacity of the skin while deeply preserving moisture, can improve the skin problems of relaxation, dryness, desquamation, roughness, darkness and the like after long-term use, and helps the skin to recover tender.
The substances such as niacinamide, squalane and the like become conventional functional components in skin care products and can play basic whitening and moisturizing effects, and consumers have higher and higher requirements on the functions of the skin care products on the market and simultaneously keep the low sensitivity and the pure natural property of the skin care product components. Therefore, in addition to the basic formulation, small amounts of plant extracts are often added to skin care products to achieve specific effects. Conventional plant extracts such as rose extract, glycyrrhiza glabra extract, honeysuckle extract, scutellaria extract and the like are adopted, but the functional characteristics of the plant extracts in the prior art are still single and are often matched for use.
Kenaf malaysia, Hibiscus L, Hibiscus syriacus, annual herb bast fiber crops, soft bast fibers, strong fiber tension, strong adaptability to climate and environment, and has the characteristics of drought resistance, saline-alkali resistance, barren resistance and the like, and easy cultivation. Kenaf is an important raw material in the traditional hemp spinning industry, and the fiber of the kenaf is developed into various products. For a long time, research and development of the kenaf mostly focuses on fibers, and breeding targets mostly focus on improving the yield and quality of the fibers. However, other parts of kenaf correspondingly have different biological activities and functional characteristics, for example, kenaf seed oil extracted from kenaf seeds can be further processed to obtain biodiesel and biological lubricating oil, and the kenaf seed oil mainly contains oleic acid and linoleic acid, and has the effects of resisting cancer and oxidation, reducing blood cholesterol, preventing hypertension, preventing atherosclerosis and the like; radix et rhizoma Rhei extract can be prepared from radix et rhizoma Rhei, and can be used for treating cardiovascular diseases; the kenaf leaves with the most abundant content of phenolic compounds have high total phenol content and protein content, the nutritive value of the kenaf leaves is equivalent to that of alfalfa, the kenaf leaves are rich in various vitamins and amino acids, the kenaf leaves are good vegetable protein feed raw materials and are also commonly used as feed processing, but the inventor finds that the extract of the kenaf leaves after extraction contains a large amount of chlorogenic acid, coffee auxiliary agents, kaempferol, hydrated catechin and the like, and the kenaf leaf extract has good tyrosinase resistance and can also play a role in skin tightening.
Further, the whitening and firming plant essence skin care emulsion comprises the following raw materials: 2-4% of jojoba oil, 1.5-2% of squalane, 0.35-0.5% of nicotinamide, 0.5-1% of polyglycerol stearate, 1.5-2% of tocopherol acetate, 10-12% of glycerol, 0.05-0.1% of methyl paraben, 0.2-0.3% of allantoin, 0.2-0.5% of mannan, 3-5% of kenaf extract and the balance of water.
Preferably, the dogwood leaf extract is prepared by the following method: cleaning the kenaf leaves with water, airing, and storing at-80 to-60 ℃ for 10 to 12 hours; then freeze-drying at-50-40 deg.C for 40-48 h, taking out and grinding to obtain folium Cannabis powder; weighing 3-5 g of kenaf leaf powder, adding 60-100 mL of an ammonia alcohol solution, extracting at 70-75 ℃ for 2-3 h, cooling and filtering, keeping supernatant, taking filter residue, adding an ammonia alcohol solution with the same mass, extracting for 2-3 h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 55-60 ℃ to obtain a paste extract, namely the kenaf leaf extract.
However, in the process of preparing the whitening and firming plant essence skin care emulsion, the emulsion is easy to cause unstable texture after the kenaf extract is added, uniform emulsion is difficult to form, and the storage stability of the product is poor. Therefore, it is necessary to add a stabilizer, a thickener, and the like to improve the state of the emulsion on this basis.
Bacterial cellulose, chemically identical to wood or plant cellulose, but obtained by fermentation in the pure state, consists of long fibers of nanometric thickness (high aspect ratio). The use of bacterial cellulose in biomedical applications has been significantly studied, as has the production of composites, the production and stabilization of emulsions and other food systems, optoelectronics, and others in most fields. In recent years, bacterial cellulose has been applied in the development of cosmetic masks as a substrate for hydrophilic cosmetic compounds for skin care, for moisturizing, rejuvenating, delaying aging and wound treatment. The inventor finds that the combination of the bacterial cellulose and the kenaf leaf extract can effectively improve the whitening effect and the stability of the kenaf leaf extract, and phenolic compounds in the kenaf leaf extract have an amphiphilic structure as plant secondary metabolites, namely the phenolic compounds contain hydrophilic groups and hydrophobic aromatic groups. Therefore, the structure can interact with the bacterial cellulose through non-covalent interaction, such as hydrogen bond and hydrophobic force, and the bonding is more compact and the hydrophobic interaction is stronger compared with the bonding of single phenolic substances due to more aromatic groups contained in the kenaf extract.
Most preferably, the whitening and firming plant essence skin care emulsion comprises the following raw materials: 2-4% of jojoba oil, 1.5-2% of squalane, 0.35-0.5% of nicotinamide, 0.5-1% of polyglycerol stearate, 1.5-2% of tocopherol acetate, 10-12% of glycerol, 0.05-0.1% of methyl paraben, 0.2-0.3% of allantoin, 0.2-0.5% of mannan, 3-5% of kenaf extract-bacterial cellulose complex and the balance of water.
Preferably, the kenaf extract-bacterial cellulose compound is prepared by the following method: cleaning the kenaf leaves with water, airing, and storing at-80 to-60 ℃ for 10 to 12 hours; then freeze-drying at-50-40 deg.C for 40-48 h, taking out and grinding to obtain folium Cannabis powder; weighing 3-5 g of kenaf powder, adding 60-100 mL of an ammonia alcohol solution, extracting at 70-75 ℃ for 2-3 h, cooling, filtering, keeping supernatant, taking filter residue, adding an ammonia alcohol solution with equal mass, extracting for 2-3 h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 55-60 ℃ to obtain a paste extract; and then 0.5-1 g of bacterial cellulose freeze-dried powder is added into the paste extract, and the mixture is stirred and mixed uniformly.
The whitening and firming plant essence skin care emulsion is prepared by the following method, and comprises the following steps:
s1, weighing jojoba oil, squalane, nicotinamide, polyglycerol stearate, tocopherol acetate, glycerol, methyl paraben, allantoin, mannan and water according to the formula, uniformly mixing, heating to 75-80 ℃, stirring to completely dissolve solids, and homogenizing at the rotating speed of 2500-4500 rpm under 20-30 MPa for 10-15 min to obtain uniform white emulsion;
s2, cooling the emulsion obtained in the step S1 to 40-45 ℃, adding the kenaf extract or the kenaf extract-bacterial cellulose compound, stirring at 2000-3000 rpm for 10-15 min, and standing for 5-6 h to obtain the whitening and firming plant essence skin care emulsion.
Furthermore, the volume fraction of ethanol in the ammoniacal alcoholic solution is 55-60%, the volume fraction of ammonia gas is 5-6%, and the balance is water.
Compared with the prior art, the invention has the following beneficial effects:
1) the whitening and firming effect is good, the components are natural, and a pure natural plant formula is taken as a main component;
2) the emulsion has uniform texture and better stability;
3) low sensitization and wide audience range.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention. The operations referred to in the examples are, unless otherwise specified, all those of ordinary skill in the art.
Some raw material parameters in the comparative examples and examples of the invention are as follows:
jojoba oil, available from jia beauty cosmetics ltd, guangzhou;
squalane, CAS: 111-01-3, available from north Hu Ke Ward chemical Co., Ltd;
methylparaben, CAS: 99-76-3, available from boyuan biotechnology limited, Hubei;
polyglycerol stearate, CAS: 105437-03-4, available from Habei Handa Biotech, Inc.
N-methylmorpholine-N-oxide, CAS: 7529-22-8, available from Shanghai leaf Biotech, Inc.
Pyridine sulfate, CAS: 543-54-4, available from shanghai hakang biotechnologies, ltd.
Example 1
A preparation method of a whitening and firming plant essence skin care emulsion comprises the following steps:
s1 preparation of the kenaf extract: cleaning folium Cannabis with water, air drying, and storing at-60 deg.C for 12 hr; freeze drying at-40 deg.C for 48h, taking out, and grinding to obtain folium Sesami powder; weighing 5g of kenaf leaf powder, adding 100mL of ammoniacal alcohol solution, extracting at 75 ℃ for 3h, cooling, filtering, keeping supernatant, adding the same mass of ammoniacal alcohol solution into filter residue, extracting for 3h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 60 ℃ to obtain a paste extract, namely the kenaf leaf extract;
s2, weighing 4g of jojoba oil, 2g of squalane, 0.5g of nicotinamide, 1g of polyglycerol stearate, 2g of tocopherol acetate, 10g of glycerol, 0.05g of methyl paraben, 0.25g of allantoin, 0.3g of mannan and 76.9mL of water, uniformly mixing, heating to 75 ℃, stirring to completely dissolve solids, and homogenizing at 30MPa and 3000rpm for 12min to obtain uniform white emulsion;
s3, cooling the emulsion obtained in the step S2 to 40 ℃, adding 3g of the kenaf extract obtained in the step S1, stirring at 3000rpm for 10min, and standing for 5h to obtain the whitening and firming plant essence skin care emulsion.
The volume fraction of ethanol, the volume fraction of ammonia gas and the volume fraction of water in the ammoniacal alcohol solution are 60%, 5% and 35%, respectively.
Comparative example 1
A preparation method of a whitening and firming plant essence skin care emulsion comprises the following steps:
s1, weighing 4g of jojoba oil, 2g of squalane, 0.5g of nicotinamide, 1g of polyglycerol stearate, 2g of tocopherol acetate, 10g of glycerol, 0.05g of methyl paraben, 0.25g of allantoin, 0.3g of mannan and 79.9mL of water, uniformly mixing, heating to 75 ℃, stirring to completely dissolve solids, and homogenizing at the rotating speed of 3000rpm under 30MPa for 12min to obtain uniform white emulsion;
s2, cooling the emulsion obtained in the step S1 to 40 ℃, stirring at 3000rpm for 10min, and standing for 5h to obtain the whitening and firming plant essence skin care emulsion.
Example 2
A preparation method of a whitening and firming plant essence skin care emulsion comprises the following steps:
s1 preparation of a kenaf extract-bacterial cellulose complex: cleaning folium Cannabis with water, air drying, storing at-60 deg.C for 12 hr, freeze drying at-40 deg.C for 48 hr, taking out, and grinding to obtain folium Cannabis powder; weighing 5g of kenaf leaf powder, adding 100mL of ammoniacal alcohol solution, extracting at 75 ℃ for 3h, cooling, filtering, keeping supernatant, adding the same mass of ammoniacal alcohol solution into filter residue, extracting for 3h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 60 ℃ to obtain a kenaf leaf extract; then 0.8g of bacterial cellulose freeze-dried powder is added into the kenaf extract to be uniformly stirred to obtain a kenaf extract-bacterial cellulose compound;
s2, weighing 4g of jojoba oil, 2g of squalane, 0.5g of nicotinamide, 1g of polyglycerol stearate, 2g of tocopherol acetate, 10g of glycerol, 0.05g of methyl paraben, 0.25g of allantoin, 0.3g of mannan and 76.9mL of water, uniformly mixing, heating to 75 ℃, stirring to completely dissolve solids, and homogenizing at the rotating speed of 3000rpm under 30MPa for 12min to obtain uniform white emulsion;
s3, cooling the emulsion obtained in the step S2 to 40 ℃, adding 3g of the kenaf extract-bacterial cellulose compound prepared in the step S1, stirring at 3000rpm for 10min, and standing for 5h to obtain the whitening and firming plant essence skin care emulsion.
The volume fraction of ethanol, the volume fraction of ammonia gas and the volume fraction of water in the ammoniacal alcohol solution are 60%, 5% and 35%, respectively.
The bacterial cellulose is a fibrous nano material with an ultra-high length-diameter ratio, which is obtained by taking saccharides as raw materials and performing biological fermentation on Acetobacter aceti, wherein the diameter of the fiber is 50-100 nm, the length of the fiber is more than 20um, and the water absorption rate is about 200 times, and freeze-dried bacterial cellulose with the particle size is used in the invention: 50-100 nm, available from Guilin Qihong science and technology Co.
Example 3
A preparation method of a whitening and firming plant essence skin care emulsion comprises the following steps:
s1 preparation of a kenaf extract-bacterial cellulose complex: cleaning folium Cannabis with water, air drying, and storing at-60 deg.C for 12 hr; freeze drying at-40 deg.C for 48h, taking out, and grinding to obtain folium Sesami powder; weighing 5g of kenaf leaf powder, adding 100mL of ammoniacal alcohol solution, extracting at 75 ℃ for 3h, cooling, filtering, keeping supernatant, adding the same mass of ammoniacal alcohol solution into filter residue, extracting for 3h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 60 ℃ to obtain a kenaf leaf extract; adding 0.8g of composite bacterial cellulose into the kenaf extract, and uniformly stirring;
s2, weighing 4g of jojoba oil, 2g of squalane, 0.5g of nicotinamide, 1g of polyglycerol stearate, 2g of tocopherol acetate, 10g of glycerol, 0.05g of methyl paraben, 0.25g of allantoin, 0.3g of mannan and 76.9mL of water, uniformly mixing, heating to 75 ℃, stirring to completely dissolve solids, and homogenizing at the rotating speed of 3000rpm under 30MPa for 12min to obtain uniform white emulsion;
s3, cooling the emulsion obtained in the step S2 to 40 ℃, adding 3g of the kenaf extract-bacterial cellulose compound prepared in the step S1, stirring at 3000rpm for 10min, and standing for 5h to obtain the whitening and firming plant essence skin care emulsion.
The volume fraction of ethanol, the volume fraction of ammonia gas and the volume fraction of water in the ammoniacal alcohol solution are 60%, 5% and 35%, respectively.
The composite bacterial cellulose is prepared by the following method: adding 2g of freeze-dried bacterial cellulose into 10mL of 0.1mol/L NaOH aqueous solution, soaking for 12h, then washing for 4 times by using distilled water, then dropwise adding 3mL of N-methylmorpholine-N-oxide, wet-grinding at 9000rpm, then weighing 0.65g of pyridine sulfate, continuously stirring, slowly adding 5mL of absolute ethyl alcohol, sealing by using a preservative film, standing for 8h, carrying out suction filtration to obtain filtrate, then adding 0.5g of sodium carboxymethyl cellulose, heating to 80 ℃, then stirring at 300rpm for 12h, carrying out autoclaved treatment at 121 ℃ for 20 min, taking out, cooling to room temperature, and then carrying out freeze drying at-40 ℃ for 10h to obtain the composite bacterial cellulose.
The inventor finds that the whitening effect can be remarkably improved after the bacterial cellulose is combined with the kenaf extract, and the bacterial cellulose is an excellent carrier matrix and can effectively protect the biological activity of the kenaf extract, but a small part of the bacterial cellulose is easy to agglomerate after being added into the emulsion, so that the bacterial cellulose is further treated, and the stability of the emulsion is further improved by combining a small amount of N-methylmorpholine-N-oxide, pyridine sulfate, carboxymethyl cellulose and the bacterial cellulose.
Test example 1
The whitening and tightening plant essence skin care emulsions of examples 1 to 3 and comparative example 1 were subjected to whitening evaluation tests in reference to the test method of the society of daily chemicals of Shanghai Standard T/SHRH 015-. The method comprises the following specific steps: a10 mL test tube was used to set up sample tubes (T), sample background (T0), enzyme reaction tubes (C) and solvent background (C0), 3 parallel tubes were set up for each sample concentration of sample tubes (T), and 3 parallel tubes were set up for enzyme reaction tubes (C). 1mL of the same concentration sample solution was added to each of the sample tube (T) and the sample background (T0), and 1mL of disodium hydrogenphosphate-citric acid buffer was added to each of the enzyme reaction tube (C) and the solvent background (C0). 0.5mL of tyrosinase solution was added to each of the sample tube (T) and the enzyme reaction tube (C), the sample background (T0) and the solvent background (C0) were replaced with 0.5mL of disodium hydrogen phosphate-citric acid buffer, the samples and tyrosinase were mixed well, and incubated in a 37 ℃ water bath for 10 minutes. And sequentially adding 2mL of levodopa solution into each tube, controlling the reaction time of each tube to be 5 minutes, immediately transferring each tube of reaction solution into a cuvette, and measuring the light absorption value at 475 nm. The calculation formula is as follows:
TABLE 1 tyrosinase activity inhibition test results Table
| Inhibition rate/%) | |
| Comparative example 1 | 57.05％ |
| Example 1 | 73.08％ |
| Example 2 | 76.52％ |
| Example 3 | 77.69％ |
As can be seen from table 1, the whitening emulsion containing the kenaf extract has a significant whitening effect, and the stronger the inhibition effect on tyrosinase activity, the better the effect of inhibiting melanin production. The whitening effect of the kenaf extract can be further effectively improved after the bacterial cellulose and the kenaf extract are combined, and phenolic compounds in the kenaf extract have an amphiphilic structure as plant secondary metabolites, namely the phenolic compounds contain hydrophilic groups and hydrophobic aromatic groups. Therefore, the structure can interact with the bacterial cellulose through non-covalent interaction, such as hydrogen bond and hydrophobic force, and the bonding is more compact and the hydrophobic interaction is stronger compared with the bonding of single phenolic substances due to more aromatic groups contained in the kenaf extract. After the bacterial cellulose is combined with the kenaf leaf extract, the kenaf leaf extract has better permeability and can better exert the functional activity.
Test example 2
The whitening and tightening plant essence skin care emulsions of examples 1-3 and comparative example 1 were subjected to stability tests, and the prepared emulsions were subjected to high-temperature, low-temperature and cold-hot alternate storage stability tests with reference to GB/T29665-2013. Centrifuging at 3000rpm for 30min, and observing whether the emulsion is layered; continuously keeping the temperature at 48 ℃ for 20 days, then recovering the room temperature and keeping the room temperature for more than 8 hours, and observing whether the emulsion has layering, solid precipitation or other inhomogeneous phenomena; continuously freezing at-25 deg.C for 20d, recovering to room temperature, maintaining for more than 8h, and observing whether the emulsion has layering, solid precipitation or other inhomogeneous phenomenon; alternately circulating for 24h at 48 deg.C and-25 deg.C for 20d, recovering to room temperature, maintaining for more than 8h, and observing whether the emulsion has layering, solid precipitation or other inhomogeneous phenomenon. In the above test, if the emulsions have no delamination, solids precipitation or other inhomogeneities, the stability test is passed, otherwise the stability test is failed. The test results are shown in Table 2.
Table 2 emulsion stability test results
| High temperature | Low temperature | Alternating cold and hot | |
| Example 1 | Do not pass through | By passing | Do not pass through |
| Example 2 | By passing | By passing | Do not pass through |
| Example 3 | By passing | By passing | By passing |
| Comparative example 1 | Do not pass through | By passing | Do not pass through |
The storage stability of the emulsion is tested, and the test result shows that the high-temperature storage stability of the emulsion added with the bacterial cellulose is obviously improved, but partial sedimentation occurs in cold and hot alternate storage.
Test example 3
The whitening and firming plant essence skin care emulsions of examples 1 to 3 and comparative example 1 were subjected to an oxidation resistance test, and the emulsions prepared in examples and comparative examples were stored for 0 day and 25 ℃ for 60 days in a sealed manner to measure DPPH radical scavenging rates, respectively: taking 3mL of the same volume of the solution to be detected and 2 multiplied by 10﹣4mixing the solution of DPPH in mol/L (A1 tube); taking equal volume of absolute ethyl alcohol and 2 multiplied by 10﹣4mixing the solution of DPPH in mol/L (A2 tube); taking absolute ethyl alcohol with the same volume and uniformly mixing the absolute ethyl alcohol with a solution to be detected (A3 tube); after 30min of dark reaction at 30 ℃, the absorbance values of tubes A1, A2 and A3 were measured at 517nm with distilled water as blank and recorded as ODA1, ODA2 andODA 3. DPPH radical clearance was calculated according to the following formula, and the test results are shown in table 3:
TABLE 3 DPPH radical scavenging Rate test results Table
The higher the DPPH free radical clearance rate, the stronger the oxidation resistance of the sample, the higher the oxidation resistance due to the large amount of chlorogenic acid, coffee adjuvant, kaempferol, hydrated catechin and the like contained in the kenaf extract, while the addition of the bacterial cellulose during the emulsion processing has a better effect on the phenolic components in the kenaf extract, and the loss rate during the storage period is lower than that of the compound bacterial cellulose, as can be seen from comparative examples 2 and 3, the effectiveness of the active components of the whitening emulsion during the long-term storage period is further enhanced by the compound bacterial cellulose.
Claims (10)
1. The whitening and firming plant essence skin care emulsion is characterized by comprising the following raw materials: jojoba oil, squalane, nicotinamide, polyglycerol stearate, tocopherol acetate, glycerol, methyl paraben, allantoin, mannan, and water.
2. The whitening and firming plant essence skin care emulsion is characterized by comprising the following raw materials: jojoba oil, squalane, nicotinamide, polyglycerol stearate, tocopherol acetate, glycerol, methyl paraben, allantoin, mannan, kenaf extract and water.
3. The whitening and tightening plant essence skin care emulsion as defined in claim 2, comprising the following raw materials by mass: 2-4% of jojoba oil, 1.5-2% of squalane, 0.35-0.5% of nicotinamide, 0.5-1% of polyglycerol stearate, 1.5-2% of tocopherol acetate, 10-12% of glycerol, 0.05-0.1% of methyl paraben, 0.2-0.3% of allantoin, 0.2-0.5% of mannan, 3-5% of kenaf extract and the balance of water.
4. The whitening and tightening plant essence skin care emulsion as claimed in claim 2 or 3, wherein the kenaf extract is prepared by the following method: cleaning the kenaf leaves with water, airing, and storing at-80 to-60 ℃ for 10 to 12 hours; then freeze-drying at-50-40 deg.C for 40-48 h, taking out and grinding to obtain folium Cannabis powder; weighing 3-5 g of kenaf leaf powder, adding 60-100 mL of an ammonia alcohol solution, extracting at 70-75 ℃ for 2-3 h, cooling and filtering, keeping supernatant, taking filter residue, adding an ammonia alcohol solution with the same mass, extracting for 2-3 h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 55-60 ℃ to obtain a paste extract, namely the kenaf leaf extract.
5. The whitening and firming plant essence skin care emulsion is characterized by comprising the following raw materials in percentage by mass: 2-4% of jojoba oil, 1.5-2% of squalane, 0.35-0.5% of nicotinamide, 0.5-1% of polyglycerol stearate, 1.5-2% of tocopherol acetate, 10-12% of glycerol, 0.05-0.1% of methyl paraben, 0.2-0.3% of allantoin, 0.2-0.5% of mannan, 3-5% of kenaf extract-bacterial cellulose complex and the balance of water.
6. The whitening and tightening plant essence skin care emulsion as claimed in claim 5, wherein the kenaf extract-bacterial cellulose complex is prepared by the following method: cleaning the kenaf leaves with water, airing, and storing at-80 to-60 ℃ for 10 to 12 hours; then freeze-drying at-50-40 deg.C for 40-48 h, taking out and grinding to obtain folium Cannabis powder; weighing 3-5 g of kenaf powder, adding 60-100 mL of an ammonia alcohol solution, extracting at 70-75 ℃ for 2-3 h, cooling, filtering, keeping supernatant, taking filter residue, adding an ammonia alcohol solution with equal mass, extracting for 2-3 h, filtering, combining the two filtrates, and performing reduced pressure fractionation at 55-60 ℃ to obtain a paste extract; and then 0.5-1 g of bacterial cellulose freeze-dried powder is added into the paste extract, and the mixture is stirred and mixed uniformly.
7. The preparation method of the whitening and tightening plant essence skin care emulsion as claimed in any one of claims 2 to 6, characterized by comprising the following steps:
s1, weighing jojoba oil, squalane, nicotinamide, polyglycerol stearate, tocopherol acetate, glycerol, methyl paraben, allantoin, mannan and water according to the formula, uniformly mixing, heating to 75-80 ℃, stirring to completely dissolve solids, and homogenizing to obtain uniform white emulsion;
s2, cooling the emulsion obtained in the step S1 to 40-45 ℃, adding the kenaf extract or the kenaf extract-bacterial cellulose compound, uniformly stirring, and standing for 5-6 hours to obtain the whitening and firming plant essence skin care emulsion.
8. The method for preparing the whitening and tightening plant essence skin care lotion according to claim 7, wherein the homogenizing conditions in the step S1 are as follows: homogenizing at 2500-4500 rpm under 20-30 MPa for 10-15 min.
9. The method for preparing the whitening and tightening plant essence skin care lotion according to claim 7, wherein the stirring conditions in the step S2 are as follows: stirring at 2000-3000 rpm for 10-15 min.
10. The whitening and tightening plant essence skin care emulsion as claimed in claim 7, wherein the volume fraction of ethanol in the ammoniacal alcohol solution is 55-60%, the volume fraction of ammonia gas is 5-6%, and the balance is water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210026628.3A CN114272165B (en) | 2022-01-11 | 2022-01-11 | Skin-whitening and tightening plant essence skin-care emulsion and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210026628.3A CN114272165B (en) | 2022-01-11 | 2022-01-11 | Skin-whitening and tightening plant essence skin-care emulsion and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114272165A true CN114272165A (en) | 2022-04-05 |
| CN114272165B CN114272165B (en) | 2024-01-16 |
Family
ID=80880722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210026628.3A Active CN114272165B (en) | 2022-01-11 | 2022-01-11 | Skin-whitening and tightening plant essence skin-care emulsion and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114272165B (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007010478A2 (en) * | 2005-07-18 | 2007-01-25 | Sederma | Slimming cosmetic compositions |
| CN101376905A (en) * | 2008-10-10 | 2009-03-04 | 上海众伟生化有限公司 | Method for producing fermentable sugar by red ramie bark fibre enzymolysis |
| CN101492837A (en) * | 2009-03-03 | 2009-07-29 | 江苏盛丰登泰生物技术有限公司 | Process for producing bacteria cellulose fibre with high degree of polymerization |
| KR20110081433A (en) * | 2010-01-08 | 2011-07-14 | 강원대학교산학협력단 | Composition for external application to the skin containing hibiscus cannabinus extract |
| CN105193882A (en) * | 2015-10-30 | 2015-12-30 | 中国科学院昆明植物研究所 | Hibiscus cannabinus extract as well as cosmetic composition and application thereof |
| CN110403858A (en) * | 2018-04-28 | 2019-11-05 | 南京理工大学 | Bacteria cellulose/Pu'er tea composite functional material and preparation method thereof |
-
2022
- 2022-01-11 CN CN202210026628.3A patent/CN114272165B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007010478A2 (en) * | 2005-07-18 | 2007-01-25 | Sederma | Slimming cosmetic compositions |
| CN101376905A (en) * | 2008-10-10 | 2009-03-04 | 上海众伟生化有限公司 | Method for producing fermentable sugar by red ramie bark fibre enzymolysis |
| CN101492837A (en) * | 2009-03-03 | 2009-07-29 | 江苏盛丰登泰生物技术有限公司 | Process for producing bacteria cellulose fibre with high degree of polymerization |
| KR20110081433A (en) * | 2010-01-08 | 2011-07-14 | 강원대학교산학협력단 | Composition for external application to the skin containing hibiscus cannabinus extract |
| CN105193882A (en) * | 2015-10-30 | 2015-12-30 | 中国科学院昆明植物研究所 | Hibiscus cannabinus extract as well as cosmetic composition and application thereof |
| CN110403858A (en) * | 2018-04-28 | 2019-11-05 | 南京理工大学 | Bacteria cellulose/Pu'er tea composite functional material and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| IGOR S. MAKAROV, ETAL: "Films of Bacterial Cellulose Prepared from Solutions in N-Methylmorpholine-N-Oxide: Structure and Properties", 《 PROCESSES.》, vol. 8, no. 2, pages 171 * |
| 吉立, 《广东化工》, vol. 39, no. 11, pages 16 - 17 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN114272165B (en) | 2024-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111407719B (en) | Skin barrier repair compound, face cream and preparation method thereof | |
| CN107308030A (en) | A kind of anti-aging reinforcing gel cream | |
| CN110755328A (en) | Beautifying, moisturizing and repairing composition and application thereof | |
| CN109330954B (en) | Whitening skin brightening lotion, preparation method thereof and tyrosinase inhibitor | |
| KR101375137B1 (en) | A cosmetic composition comprising fermented extract of Scutellaria baicalensis using Leatiporus sulphureus var. miniatus for skin moisturizing | |
| CN114848541A (en) | Anti-aging and wrinkle-removing composition and preparation method thereof, and cosmetic and preparation method thereof | |
| CN109091422B (en) | Cosmetic containing Pleurotus citrinopileatus extract and its preparation method | |
| CN108815072A (en) | A kind of plant composition fermentation magma and its preparation method and application | |
| CN115137673A (en) | Fermented cosmetic composition and preparation method and application thereof | |
| CN108714126A (en) | Skin care compositions and the preparation method and application thereof with moisturizing and anti-oxidation efficacy | |
| JP2023171950A (en) | Anti-aging agent, antioxidant, anti-inflammatory agent, and whitening agent, as well as cosmetic | |
| CN112089666A (en) | Antioxidant composition and preparation method and application thereof | |
| CN114272165B (en) | Skin-whitening and tightening plant essence skin-care emulsion and preparation method thereof | |
| CN114788806A (en) | Traditional Chinese medicine composition fermented primary pulp with antioxidant and whitening integrated effects and preparation method and application thereof | |
| CN115137675A (en) | Compound plant extract with moisturizing effect and application thereof | |
| CN114432225A (en) | Sunscreen skin care product and preparation method thereof | |
| KR102047442B1 (en) | Composite for mask pack | |
| CN112915060A (en) | Emulsion containing anti-aging composition and preparation method thereof | |
| CN114469816B (en) | Antioxidant plant essence skin care emulsion and preparation method thereof | |
| CN112494408A (en) | Whitening and inflammation diminishing mask liquid and preparation method thereof | |
| CN111728901A (en) | Anti-aging composition and preparation method and application thereof | |
| JP2020193197A (en) | Process for extracting plants | |
| CN111544335A (en) | Essence containing soluble collagen and malachite extract and preparation method thereof | |
| CN113181088A (en) | Collagenase inhibitor, preparation method thereof and muscle penetrating water containing collagenase inhibitor | |
| CN110742833B (en) | Acne-removing, whitening and anti-aging essential oil composition as well as preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20231219 Address after: No. 95 Donghua Huasheng South Road, Renhe Town, Baiyun District, Guangzhou City, Guangdong Province (Airport Baiyun) Applicant after: Guangzhou Yirenkang Biopharmaceutical Technology Co.,Ltd. Address before: 518019 Room 408, 4th floor, 38 Buxin village, Luohu District, Shenzhen City, Guangdong Province Applicant before: SHENZHEN RUNBANG ZHIJIA BIOTECHNOLOGY Co.,Ltd. |
|
| TA01 | Transfer of patent application right | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |