CN114259424A - Anhydrous antibacterial toothpaste containing peach carin and cymene and preparation method thereof - Google Patents
Anhydrous antibacterial toothpaste containing peach carin and cymene and preparation method thereof Download PDFInfo
- Publication number
- CN114259424A CN114259424A CN202111596184.9A CN202111596184A CN114259424A CN 114259424 A CN114259424 A CN 114259424A CN 202111596184 A CN202111596184 A CN 202111596184A CN 114259424 A CN114259424 A CN 114259424A
- Authority
- CN
- China
- Prior art keywords
- cymene
- parts
- making machine
- peach
- anhydrous
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses an anhydrous antibacterial toothpaste containing peach carin phenol and cymene and a preparation method thereof, wherein the toothpaste comprises the following components in parts by weight: 0.05-0.1 part of cymene, 0.2-0.5 part of peach carin, 50-70 parts of humectant, 0.2-2 parts of thickening agent, 0.2-3 parts of surfactant, 10-30 parts of abrasive, 0.08-0.4 part of sweetening agent and 0.5-3 parts of essence. The invention relates to the technical field of antibacterial toothpaste, and particularly provides anhydrous antibacterial toothpaste containing peach carin and cymene and a manufacturing method thereof.
Description
Technical Field
The invention relates to the technical field of antibacterial toothpaste, in particular to anhydrous antibacterial toothpaste containing peach carin and cymene and a manufacturing method thereof.
Background
Along with the improvement of living standard, people pay more and more attention to personal hygiene, and toothpaste has become a necessity for life of people for a long time. Bacteria in plaque on teeth, especially anaerobes and their products, are the major cause of gingivitis and periodontal disease. Research shows that effective control of the number of pathogenic bacteria in the oral cavity is of great significance for preventing and treating common oral problems and diseases. The tooth brushing can effectively improve the oral environment, and the proper amount of the toothpaste with the effects of bacteriostasis and anti-inflammation is beneficial to preventing oral diseases and eliminating or reducing oral peculiar smell. However, the traditional toothpaste has poor antibacterial effect on the oral cavity, has no auxiliary functions except simple functions of cleaning the oral cavity and teeth, and cannot keep the oral cavity clean for a long time.
Cymene and peach phyrin have excellent bacteriostatic and anti-inflammatory functions, and are bacteriostatic and anti-inflammatory components suitable for oral care. O-cymene-5-ol is an excellent antifungal component, is an isomer of thymol, has good permeability, is an oral biomembrane and is not easily and effectively killed by a bactericide which only disinfects on the surface, and cymene can permeate the oral biomembrane to better reduce dental plaque. The gingerol is a protein derived from Palo chinensis which is a new zealand, which is a natural plant bacteriostatic agent having an outstanding bacteriostatic activity against Staphylococcus aureus.
However, cymene and persimmon phenol are components that are hardly soluble in water, and therefore, it is difficult to exert their bacteriostatic effects in a general aqueous toothpaste formulation system. In the past, some surfactants are needed to be added into toothpaste, and the addition of solubilizer reduces the antiseptic and antibacterial performance of toothpaste. In order to solve the problems in the prior art, the invention discloses a formula scheme of anhydrous toothpaste, which adopts an anhydrous toothpaste process to bear functional substances and has good antibacterial and anti-inflammatory effects.
Disclosure of Invention
In view of the above, the present invention provides an anhydro-antibacterial toothpaste containing sinol and cymene and a method for manufacturing the same, in which an anhydro-toothpaste system is used instead of a hydrous toothpaste system, and glycerin, polyethylene glycol-8, propylene glycol, and the like are used as a liquid phase, thereby ensuring better stability and effect of cymene and cymene phenol, better exerting antibacterial effect of cymene and cymene phenol in the anhydrous system, and reducing the usage of toothpaste.
The invention provides the following technical scheme: the invention provides an anhydrous antibacterial toothpaste containing peach carin phenol and cymene, which comprises the following components in parts by weight: 0.05-0.1 part of cymene, 0.2-0.5 part of peach carin, 50-70 parts of humectant, 0.2-2 parts of thickening agent, 0.2-3 parts of surfactant, 10-30 parts of abrasive, 0.08-0.4 part of sweetening agent and 0.5-3 parts of essence.
Preferably, the antibacterial anhydrous toothpaste containing persimmon phenol and cymene comprises the following components in parts by weight: 0.05-0.1 part of cymene, 0.3-0.5 part of peach carin, 58-70 parts of humectant, 0.5-2 parts of thickening agent, 0.2-3 parts of surfactant, 15-30 parts of abrasive, 0.08-0.3 part of sweetening agent and 0.5-3 parts of essence.
Further, the humectant is selected from one or more of glycerin, polyethylene glycol-8 or propylene glycol.
Further, the thickening agent is selected from one or two of carbomer or polyvinylpyrrolidone.
Further, the surfactant is selected from one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate or sodium methyl lauroyl taurate.
Further, the abradant is silicon dioxide.
Preferably, the sweetener is selected from one or more of sucralose, sodium saccharin or aspartame.
The invention relates to a method for manufacturing an anhydrous bacteriostatic toothpaste containing persimmon phenol and cymene, which comprises the following steps:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
The invention with the structure has the following beneficial effects: the invention provides an anhydrous antibacterial toothpaste containing peach carin phenol and cymene and a manufacturing method thereof, which adopts components such as glycerin, polyethylene glycol-8 and propylene glycol as liquid phases, and replaces a water toothpaste system with a water-free toothpaste system, thereby ensuring that the cymene and the peach carinol have better stability and effect, leading the cymene and the peach carinol to better exert the antibacterial effect in the anhydrous system and reducing the usage amount of the toothpaste.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
An anhydrous antibacterial toothpaste containing peach phenol and cymene, comprising the following components in parts by weight: 0.05 part of cymene, 0.3 part of peach carina phenol, 60 parts of glycerol, 10 parts of propylene glycol, 0.9 part of polyvinylpyrrolidone, 3 parts of a composition of sodium lauroyl sarcosinate and sodium methyl lauroyl taurate, 25 parts of silicon dioxide, 0.15 part of a composition of sucralose, sodium saccharin and aspartame and 0.5 part of essence.
The invention relates to a method for manufacturing an anhydrous bacteriostatic toothpaste containing persimmon phenol and cymene, which comprises the following steps:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
Example 2
An anhydrous antibacterial toothpaste containing peach phenol and cymene, comprising the following components in parts by weight: 0.075 part of cymene, 0.3 part of peach carina phenol, 55 parts of glycerol, 813 parts of polyethylene glycol, 0.8 part of carbomer, 2 parts of sodium lauryl sulfate, 20 parts of silicon dioxide, 0.24 part of sucralose and 1.3 parts of essence.
The invention relates to a method for manufacturing an anhydrous bacteriostatic toothpaste containing persimmon phenol and cymene, which comprises the following steps:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
Example 3
An anhydrous antibacterial toothpaste containing peach phenol and cymene, comprising the following components in parts by weight: 0.075 part of cymene, 0.4 part of peach carin phenol, 60 parts of glycerol, 815 parts of polyethylene glycol, 1.1 parts of polyvinylpyrrolidone, 1.6 parts of sodium lauroyl sarcosinate, 20 parts of silicon dioxide, 0.24 part of saccharin sodium and 1.45 parts of essence.
The invention relates to a method for manufacturing an anhydrous bacteriostatic toothpaste containing persimmon phenol and cymene, which comprises the following steps:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
Example 4
An anhydrous antibacterial toothpaste containing peach phenol and cymene, comprising the following components in parts by weight: 0.075 part of cymene, 0.5 part of peach carin, 60 parts of glycerol, 810 parts of polyethylene glycol, 5 parts of propylene glycol, 0.8 part of polyvinylpyrrolidone, 1.6 parts of sodium methyl lauroyl taurate, 22 parts of silicon dioxide, 0.24 part of aspartame and 1.75 parts of essence.
The invention relates to a method for manufacturing an anhydrous bacteriostatic toothpaste containing persimmon phenol and cymene, which comprises the following steps:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
Example 5
An anhydrous antibacterial toothpaste containing peach phenol and cymene, comprising the following components in parts by weight: 0.1 part of cymene, 0.5 part of peach carina phenol, 60 parts of glycerol, 1.3 parts of a composition of carbomer and polyvinylpyrrolidone, 3 parts of a composition of sodium lauryl sulfate, sodium lauroyl sarcosinate and sodium methyl lauroyl taurate, 20 parts of silicon dioxide, 0.3 part of a composition of sucralose, sodium saccharin and aspartame and 1.8 parts of essence.
The invention relates to a method for manufacturing an anhydrous bacteriostatic toothpaste containing persimmon phenol and cymene, which comprises the following steps:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
The antibacterial effect of the toothpaste containing peach carin in an aqueous system, the toothpaste in an anhydrous system and the toothpaste in the anhydrous system compounded by 0.1% of cymene and 0.5% of peach carin is detected respectively, and the detection results are as follows:
(1) the bacteriostatic effect of the aqueous solution of peach phenol is shown in the following table (bacteriostatic ratio is 10min data):
| content of phenol in peach girders | Escherichia coli | Staphylococcus aureus | Candida albicans |
| 0.3％ | 46.35％ | 54.59％ | 56.14％ |
| 0.5％ | 57.65％ | 65.22％ | 62.71％ |
The above results show that: the antibacterial effect of the aqueous solution of the peach girder phenol on three pathogenic bacteria is not good enough, and the strong antibacterial effect cannot be achieved.
(2) The bacteriostatic effect of the glycerol solution of peach girders phenol is shown in the following table (bacteriostatic ratio is 10min data):
| myoglobin content (0.5) | Escherichia coli | Staphylococcus aureus |
| 2min | 99.88％ | 62.17％ |
| 5min | 99.95％ | 67.44％ |
| 10min | 99.56％ | 76.44％ |
| 20min | 99.99％ | 93.17％ |
The above results show that: the peach girder phenol glycerol solution has an obvious antibacterial effect on escherichia coli.
(3) The bacteriostatic effects of the water bacteriostatic toothpaste and the anhydrous bacteriostatic toothpaste on three pathogenic bacteria (escherichia coli, staphylococcus aureus and candida albicans) are shown in the following table (bacteriostatic rate is 10min data):
watery toothpaste (toothpaste of watery system prepared by compounding 0.1% cymene and 0.5% peach phyrin):
| escherichia coli | Staphylococcus aureus | Candida albicans | |
| 2min | 72.15％ | 63.63％ | 62.11％ |
| 5min | 69.21％ | 65.36％ | 60.22％ |
| 10min | 68.79％ | 64.43％ | 59.36％ |
Anhydrous antibacterial toothpaste:
example 1
| Escherichia coli | Staphylococcus aureus | Candida albicans | |
| 2min | 78.23％ | 73.13％ | 77.39％ |
| 5min | 83.13％ | 76.88％ | 83.36％ |
| 10min | 85.15％ | 80.26％ | 90.23％ |
Example 2
| Escherichia coli | Staphylococcus aureus | Candida albicans | |
| 2min | 83.15％ | 74.36％ | 88.91％ |
| 5min | 88.68％ | 78.35％ | 92.42％ |
| 10min | 89.36％ | 85.1％ | 94.31％ |
Example 3
| Escherichia coli | Staphylococcus aureus | Candida albicans | |
| 2min | 85.35％ | 80.78％ | 90.21％ |
| 5min | 88.68％ | 83.34％ | 98.15％ |
| 10min | 95.78％ | 89.36％ | 99.25％ |
Example 4
| Escherichia coli | Staphylococcus aureus | Candida albicans | |
| 2min | 93.15％ | 93.71％ | 90.14％ |
| 5min | 98.36％ | 94.3％ | 95.56％ |
| 10min | 99.9％ | 98.17％ | 97.32％ |
Example 5
| Escherichia coli | Staphylococcus aureus | Candida albicans | |
| 2min | 93.68％ | 95.71％ | 88.91％ |
| 5min | 99.9％ | 99.9％ | 99.9％ |
| 10min | 99.9％ | 99.9％ | 99.9％ |
From the above experimental test results, it can be seen that the bacteriostatic effect of the anhydrous toothpaste prepared by compounding 0.1% cymene and 0.5% peach blossom phenol is far better than the bacteriostatic effect of the waterborne toothpaste prepared by compounding 0.1% cymene and 0.5% peach blossom phenol on escherichia coli, staphylococcus aureus and candida albicans.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. An anhydrous antibacterial toothpaste containing peach carin and cymene, which is characterized by comprising the following components in parts by weight: 0.05-0.1 part of cymene, 0.2-0.5 part of peach carin, 50-70 parts of humectant, 0.2-2 parts of thickening agent, 0.2-3 parts of surfactant, 10-30 parts of abrasive, 0.08-0.4 part of sweetening agent and 0.5-3 parts of essence.
2. An anhydrous bacteriostatic toothpaste comprising persimmons phenol and cymene according to claim 1, comprising the following components in parts by weight: 0.05-0.1 part of cymene, 0.3-0.5 part of peach carin, 58-70 parts of humectant, 0.5-2 parts of thickening agent, 0.2-3 parts of surfactant, 15-30 parts of abrasive, 0.08-0.3 part of sweetening agent and 0.5-3 parts of essence.
3. An anhydrous bacteriostatic toothpaste comprising persimmon phenol and cymene according to claim 1, wherein said humectant is selected from one or more of glycerol, polyethylene glycol-8 or propylene glycol.
4. An anhydrous bacteriostatic toothpaste comprising persimmons phenol and cymene according to claim 1, wherein said thickening agent is selected from one or both of carbomer and polyvinylpyrrolidone.
5. An anhydrous bacteriostatic toothpaste comprising persimmons phenol and cymene according to claim 1, wherein said surfactant is selected from one or more of sodium lauryl sulfate, sodium lauroyl sarcosinate or sodium methyl lauroyl taurate.
6. An anhydrous bacteriostatic toothpaste comprising persimmon phenol and cymene according to claim 1, wherein the abrasive agent is silica.
7. An anhydrous bacteriostatic toothpaste comprising persimmon phenol and cymene according to claim 1, wherein said sweetener is selected from one or more of sucralose, sodium saccharin or aspartame.
8. A method of manufacturing an anhydro bacteriostatic toothpaste comprising peach girders phenol and cymene according to any one of claims 1-7, specifically comprising the steps of:
weighing cymene, peach carina phenol, glycerol, polyethylene glycol-8, propylene glycol, a thickening agent, a surfactant, an abrasive, a sweetening agent and essence according to the proportion for later use;
step two, adding the glycerol, the polyethylene glycol-8, the propylene glycol and the thickening agent in the step one into a homogenizer, heating to 60 ℃ by using boiled steam, homogenizing for 40-60 min, adding cymene and the peach phenol, stirring for 10-15 min, and dissolving uniformly to obtain a colloidal mixture;
pumping the colloidal mixture obtained in the step two into a paste making machine, adding the friction agent weighed in the step one, keeping the vacuum degree in the paste making machine between-0.07 Mpa and-0.095 Mpa, and stirring for 35 min;
step four, adding the surfactant and the sweetener in the step one into the paste making machine in the step three, adjusting and keeping the vacuum degree in the paste making machine between-0.065 Mpa and-0.08 Mpa, and stirring for half an hour;
step five, adding the essence obtained in the step one into a paste making machine obtained in the step four, adjusting and keeping the vacuum degree in the paste making machine between-0.05 Mpa and-0.06 Mpa, and stirring for 15min to obtain the paste of the anhydrous antibacterial toothpaste containing the peach phenols and the cymene;
step six, closing the power supply of the paste making machine, taking out a paste sample in the paste making machine for detection, opening a normal pressure valve of the paste making machine after the detection is qualified, and pumping the paste in the paste making machine into a storage pot for aging until the temperature is restored to the room temperature;
and step seven, subpackaging the paste in the step six to obtain the anhydrous bacteriostatic toothpaste containing cymene and peach carinol.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111596184.9A CN114259424A (en) | 2021-12-24 | 2021-12-24 | Anhydrous antibacterial toothpaste containing peach carin and cymene and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111596184.9A CN114259424A (en) | 2021-12-24 | 2021-12-24 | Anhydrous antibacterial toothpaste containing peach carin and cymene and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114259424A true CN114259424A (en) | 2022-04-01 |
Family
ID=80829557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202111596184.9A Pending CN114259424A (en) | 2021-12-24 | 2021-12-24 | Anhydrous antibacterial toothpaste containing peach carin and cymene and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114259424A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115025022A (en) * | 2022-07-13 | 2022-09-09 | 博雅(广州)生物科技研究院有限公司 | Efficient antibacterial toothpaste and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511112A (en) * | 2016-12-13 | 2017-03-22 | 美晨集团股份有限公司 | Toothpaste with lasting cooling and bacteriostatic effects and preparation method of toothpaste |
| CN107281013A (en) * | 2017-07-28 | 2017-10-24 | 鹰仕达（中国）有限公司 | One kind removes tooth stain and suppresses bacterial plaque toothpaste |
| CN110478298A (en) * | 2019-09-23 | 2019-11-22 | 沈阳天然纳美科技有限公司 | A kind of composition and its preparation method and application with oral health function |
| CN111888306A (en) * | 2020-07-14 | 2020-11-06 | 名臣健康用品股份有限公司 | Essence for removing blackheads and repairing rosacea and preparation method thereof |
-
2021
- 2021-12-24 CN CN202111596184.9A patent/CN114259424A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106511112A (en) * | 2016-12-13 | 2017-03-22 | 美晨集团股份有限公司 | Toothpaste with lasting cooling and bacteriostatic effects and preparation method of toothpaste |
| CN107281013A (en) * | 2017-07-28 | 2017-10-24 | 鹰仕达（中国）有限公司 | One kind removes tooth stain and suppresses bacterial plaque toothpaste |
| CN110478298A (en) * | 2019-09-23 | 2019-11-22 | 沈阳天然纳美科技有限公司 | A kind of composition and its preparation method and application with oral health function |
| CN111888306A (en) * | 2020-07-14 | 2020-11-06 | 名臣健康用品股份有限公司 | Essence for removing blackheads and repairing rosacea and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115025022A (en) * | 2022-07-13 | 2022-09-09 | 博雅(广州)生物科技研究院有限公司 | Efficient antibacterial toothpaste and preparation method thereof |
| CN115025022B (en) * | 2022-07-13 | 2023-09-05 | 湖南互美电子商务有限公司 | Antibacterial toothpaste and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2389071B1 (en) | Biofilm-removing antimicrobial compositions and uses thereof | |
| TWI330089B (en) | Enzyme containing oral composition having enhanced stability | |
| RU2597159C2 (en) | Oral care product and methods for using and preparing same | |
| NZ550744A (en) | Hydrogen peroxide-based skin disinfectant | |
| WO2011020206A1 (en) | Antiseptic pharmaceutical composition for oral hygiene and the treatment of oral diseases of microbial origin | |
| TW201102101A (en) | Dentifrice composition | |
| WO2022088724A1 (en) | Green tea active substance mouthwash composition and preparation method therefor | |
| EA022986B1 (en) | Oral care composition | |
| CN111000777A (en) | Antibacterial mouth wash | |
| CN114259424A (en) | Anhydrous antibacterial toothpaste containing peach carin and cymene and preparation method thereof | |
| CN108096047A (en) | Domiphen bromide xylitol combination of acidic mouthwash and preparation method thereof | |
| CN112057390A (en) | Toothpaste for preventing and treating dental ulcer and preparation method and application thereof | |
| JPS5929619A (en) | Preventing agent for carious tooth | |
| CN101474143A (en) | Toothpaste and preparation method thereof | |
| CN112168729A (en) | Rosemary disinfection hand sanitizer and preparation method thereof | |
| CN111265440A (en) | Rosemary antibacterial and disinfectant wash-free hand sanitizer formula | |
| KR20130116486A (en) | Oral composition for inhibiting dental plaque | |
| CN109364115B (en) | Oral composition containing licorice extract and paniculate swallowwort root extract and application thereof | |
| CN108066167A (en) | A kind of antibacterial whitening acidity mouthwash of visualization and preparation method thereof | |
| CN114177123A (en) | Aromatic Chinese herbal medicine toothpaste and preparation method thereof | |
| Figuero et al. | Supra and subgingival application of antiseptics or antibiotics during periodontal therapy | |
| CN109512740B (en) | Oral composition containing licorice extract and ovateleaf holly bark extract and application thereof | |
| CN111840188A (en) | Nursing type hand-washing-free disinfection gel and preparation method thereof | |
| CN106176471A (en) | One is pure white admires a toothpaste | |
| CN111346049A (en) | Preparation method of skin and mucous membrane disinfectant |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |