CN114206928B - Cd33靶向免疫疗法 - Google Patents

Cd33靶向免疫疗法

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Publication number
CN114206928B
CN114206928B CN202080048661.5A CN202080048661A CN114206928B CN 114206928 B CN114206928 B CN 114206928B CN 202080048661 A CN202080048661 A CN 202080048661A CN 114206928 B CN114206928 B CN 114206928B
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Prior art keywords
gly
polypeptide
cell
domain
leu
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CN202080048661.5A
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Chinese (zh)
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CN114206928A (zh
Inventor
乔丹·贾儒尔
马克·波格森
梁炜亨
凯尔·琼斯
威廉·克拉戈
安吉莉卡·萨纳布里亚
安德鲁·霍兰兹
雅各布·加诺
米尔顿·马
约翰·C·蒂默
布伦丹·P·埃克尔曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yinxi Bi Biological Science Co
Regeneron Pharmaceuticals Inc
Original Assignee
2 Savinti Biology
Yinxi Bi Biological Science Co
Regeneron Pharmaceuticals Inc
Inhibit Ltd
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Publication of CN114206928A publication Critical patent/CN114206928A/zh
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    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
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CN202080048661.5A 2019-05-08 2020-05-07 Cd33靶向免疫疗法 Active CN114206928B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962845304P 2019-05-08 2019-05-08
US62/845,304 2019-05-08
US201962898392P 2019-09-10 2019-09-10
US62/898,392 2019-09-10
PCT/US2020/031780 WO2020227474A1 (en) 2019-05-08 2020-05-07 Cd33 targeted immunotherapies

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CN114206928A CN114206928A (zh) 2022-03-18
CN114206928B true CN114206928B (zh) 2025-08-08

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US12291560B2 (en) 2018-12-14 2025-05-06 Regeneron Pharmaceuticals, Inc. Dimerizing agent regulated immunoreceptor complexes
WO2022171113A1 (zh) * 2021-02-10 2022-08-18 江苏先声药业有限公司 人cd33抗体及其用途
MX2024007057A (es) * 2021-12-10 2024-08-09 Seattle Childrens Hospital D/B/A Seattle Childrens Res Institute Métodos y composiciones para modular la actividad de un complejo inmunomodulador regulado por un agente dimerizador.
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