CA3139096A1 - Cd33 targeted immunotherapies - Google Patents

Cd33 targeted immunotherapies Download PDF

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Publication number
CA3139096A1
CA3139096A1 CA3139096A CA3139096A CA3139096A1 CA 3139096 A1 CA3139096 A1 CA 3139096A1 CA 3139096 A CA3139096 A CA 3139096A CA 3139096 A CA3139096 A CA 3139096A CA 3139096 A1 CA3139096 A1 CA 3139096A1
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CA
Canada
Prior art keywords
cell
polypeptide
domain
cells
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3139096A
Other languages
English (en)
French (fr)
Inventor
Jordan JARJOUR
Mark POGSON
Wai-Hang LEUNG
Kyle Jones
William Crago
Angelica SANABRIA
Andrew HOLLANDS
Jacob GANO
Milton MA
John C. Timmer
Brendan P. Eckelman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
2Seventy Bio Inc
Sanofi Aatd Inc
Original Assignee
Inhibrx Inc
2Seventy Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhibrx Inc, 2Seventy Bio Inc filed Critical Inhibrx Inc
Publication of CA3139096A1 publication Critical patent/CA3139096A1/en
Pending legal-status Critical Current

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C12N9/90—Isomerases (5.)
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    • C12N2740/15041—Use of virus, viral particle or viral elements as a vector
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CA3139096A 2019-05-08 2020-05-07 Cd33 targeted immunotherapies Pending CA3139096A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962845304P 2019-05-08 2019-05-08
US62/845,304 2019-05-08
US201962898392P 2019-09-10 2019-09-10
US62/898,392 2019-09-10
PCT/US2020/031780 WO2020227474A1 (en) 2019-05-08 2020-05-07 Cd33 targeted immunotherapies

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CA3139096A1 true CA3139096A1 (en) 2020-11-12

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CA3139096A Pending CA3139096A1 (en) 2019-05-08 2020-05-07 Cd33 targeted immunotherapies

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EP (1) EP3966251A4 (enExample)
JP (2) JP7765291B2 (enExample)
KR (1) KR20220031554A (enExample)
CN (1) CN114206928B (enExample)
AU (1) AU2020268379A1 (enExample)
BR (1) BR112021022356A2 (enExample)
CA (1) CA3139096A1 (enExample)
IL (1) IL287770A (enExample)
MA (1) MA55907A (enExample)
MX (1) MX2021013591A (enExample)
SG (1) SG11202111890RA (enExample)
WO (1) WO2020227474A1 (enExample)

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WO2020123947A1 (en) 2018-12-14 2020-06-18 Bluebird Bio, Inc. Dimerizing agent regulated immunoreceptor complexes
CN116867806A (zh) * 2021-02-10 2023-10-10 先声再明医药有限公司 人cd33抗体及其用途
WO2023108158A2 (en) * 2021-12-10 2023-06-15 Seattle Children's Hospital D/B/A Seattle Children's Research Institute Methods and compositions for modulating the activity of a dimerizing agent regulated immunomodulatory complex
AU2023248532A1 (en) * 2022-04-08 2024-11-21 Regeneron Pharmaceuticals, Inc. Multipartite receptor and signaling complexes
KR20250007535A (ko) * 2022-04-22 2025-01-14 인히브릭스 바이오사이언스, 인크. Siglec-8 결합 단백질 및 그 용도
WO2023230512A1 (en) 2022-05-26 2023-11-30 2Seventy Bio, Inc. Compositions for maintaining lentiviral vector and uses thereof

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US20100003253A1 (en) 2002-11-08 2010-01-07 Ablynx N.V. Single domain antibodies directed against epidermal growth factor receptor and uses therefor
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CN114206928A (zh) 2022-03-18
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IL287770A (en) 2022-01-01
US20220324942A1 (en) 2022-10-13
MA55907A (fr) 2022-03-16
JP7765291B2 (ja) 2025-11-06
US12552855B2 (en) 2026-02-17
AU2020268379A1 (en) 2022-01-06
SG11202111890RA (en) 2021-11-29
US20260132184A1 (en) 2026-05-14
KR20220031554A (ko) 2022-03-11
JP2022531719A (ja) 2022-07-08
BR112021022356A2 (pt) 2022-01-18
EP3966251A1 (en) 2022-03-16
MX2021013591A (es) 2022-02-11
CN114206928B (zh) 2025-08-08

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