CN114177234A

CN114177234A - Medicated bath formula for adjuvant therapy of herpes zoster and preparation method

Info

Publication number: CN114177234A
Application number: CN202111325733.9A
Authority: CN
Inventors: 徐志强
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-11-10
Filing date: 2021-11-10
Publication date: 2022-03-15

Abstract

The invention discloses a medicated bath formula for adjuvant therapy of herpes zoster and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The medicated bath prescription is prepared by matching the roots, stems, leaves, seeds and fruits of pure natural Chinese medicaments, has simple preparation method, can be independently operated, can be used as a medicated bath fumigation-washing prescription for dermatology, and is worthy of clinical popularization and application.

Description

Medicated bath formula for adjuvant therapy of herpes zoster and preparation method

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a medicated bath formula for adjuvant therapy of herpes zoster and a preparation method thereof.

Background

Herpes zoster is a common acute infectious skin disease. The people with high incidence of herpes zoster are mainly middle-aged and old people, and the incidence rate of the herpes zoster obviously increases with the age. Shingles is caused by varicella-zoster virus. After the virus infection, the virus is latent at the root of the nerve, and when the body resistance is low, the virus grows and grows, damages the nerve, and involves the skin along the nerve, so that a strong inflammatory reaction occurs. The clinical manifestations of shingles are erythema, papules, blisters, zonal arrangements on one side of the body with neuropathic pain.

Herpes zoster is mainly treated by medicines, and has effects of killing virus, relieving neuralgia, and shortening course of disease. In addition, physical therapy can promote nerve repair and relieve symptoms. If patients with herpes zoster are not treated in time, severe neuralgia can occur, and the patients are not healed, which seriously affects the life quality of the patients.

The traditional Chinese medicine has the obvious curative effect on treating postherpetic neuralgia, but the effect is not good enough in the aspect of antiviral treatment. In addition, the traditional Chinese medicine therapy has slow effect and complex process, patients suffer from long time, and are often used with western medicine, so that the process is complex from the perspective of the patients, the crime degree is large, the side effect of the western medicine is large, and the influence on the body is large. Based on the above, the invention designs a medicated bath formula for assisting in treating herpes zoster and a preparation method thereof, so as to solve the problems.

Disclosure of Invention

The invention aims to provide a medicated bath formula for adjuvant therapy of herpes zoster and a preparation method thereof, so as to solve the problems in the background technology.

In order to achieve the purpose, the invention provides the following technical scheme: a medicated bath formula for adjuvant therapy of herpes zoster comprises the following active ingredients in parts by weight: 25-35 parts of purslane, 25-35 parts of lysimachia christinae hance, 25-35 parts of potentilla discolor, 25-35 parts of Chinese violet, 20-30 parts of honeysuckle stem, 15-25 parts of giant knotweed, 15-25 parts of borneol, 20-30 parts of szechwan chinaberry fruit, 10-20 parts of common cnidium fruit, 10-20 parts of radix sophorae flavescentis and 10-20 parts of alum.

Furthermore, the medicated bath formula for adjuvant therapy of herpes zoster is characterized by comprising the following active ingredients in parts by weight: 30 parts of purslane, 30 parts of lysimachia christinae hance, 30 parts of discolor cinquefoil herb, 30 parts of Chinese violet, 25 parts of honeysuckle stem, 20 parts of giant knotweed rhizome, 20 parts of borneol, 25 parts of szechwan chinaberry fruit, 15 parts of common cnidium fruit, 15 parts of bitter ginseng and 15 parts of alum.

A preparation method of a medicated bath formula for adjuvant therapy of herpes zoster is characterized by comprising the following steps;

(1) preparing formula materials and an aluminum pot for later use;

(2) putting purslane, longhairy antenoron herb, discolor cinquefoil herb, Chinese violet, honeysuckle stem, tiger cane, common cnidium fruit, lightyellow sophora root, szechwan chinaberry fruit and alum materials in parts by weight into an aluminum pot, adding 7000-9000 ml of water, and decocting;

(3) adding borneol, continuously heating for 30-50 minutes to obtain medicinal bath liquid, and taking the medicinal liquid for later use.

Furthermore, in the step (1), the purslane, the longhairy antenoron herb, the potentilla discolor, the Chinese violet, the honeysuckle stem, the giant knotweed rhizome, the common cnidium fruit, the lightyellow sophora root, the szechwan chinaberry fruit and the alum are put into a grinding machine to be smashed, screened through a 100-200-mesh sieve, and the granular mixture is put into a non-woven bag.

Further, in the step (2), the raw materials are soaked for 4-8 hours, and then are decocted for 2-3 times by adding water, the raw materials are boiled with strong fire and slowly decocted with small fire, and each time of decoction is 70-120 min; after the decoction is finished, filtering the decoction to obtain filtrate and filter residue.

Furthermore, in the step (3), the borneol is completely dissolved in the water.

Compared with the prior art, the invention has the beneficial effects that: the invention adopts the traditional Chinese medicine to consider that heat-clearing, dampness-draining, detoxifying and pain-relieving are suitable for treating herpes zoster as a solution, and the potentilla discolor, the desmodium, the philippine violet herb, the Chinese violet, the Chinese medicinal herb, the honeysuckle stem, the Chinese medicinal herb, the szechwan chinaberry fruit, the Chinese medicinal herb, the giant knotweed, the blood circulation promoting, the stasis removing, the inflammation relieving, the pain relieving, the borneol, the stagnated fire, the swelling relieving, the pain relieving, the lightyellow sophora root, the common cnidium fruit, the alum, the insect killing, the itching relieving, the heat clearing and the dampness are used in the prescription;

according to the characteristics of the prior art and clinical characteristics, the external medicinal bath lotion can run through the whole treatment process of herpes zoster, is more suitable for liver and gallbladder damp-heat type (herpes zoster), can effectively avoid the burden of liver and kidney functions caused by oral administration of medicaments by external administration of skin, can directly act on affected parts, effectively shortens the course of disease, and relieves the pain of patients. The medicated bath prescription is prepared by matching the roots, stems, leaves, seeds and fruits of pure natural Chinese medicaments, has simple preparation method, can be independently operated, can be used as a medicated bath fumigation-washing prescription for dermatology, and is worthy of clinical popularization and application.

Detailed Description

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without any inventive step, are within the scope of the present invention.

The invention provides a technical scheme that:

example 1

A medicated bath formula for adjuvant therapy of herpes zoster comprises the following active ingredients in parts by weight: 25 parts of purslane, 25 parts of lysimachia christinae hance, 25 parts of discolor cinquefoil herb, 25 parts of Chinese violet, 20 parts of honeysuckle stem, 15 parts of giant knotweed rhizome, 15 parts of borneol, 20 parts of szechwan chinaberry fruit, 10 parts of common cnidium fruit, 10 parts of lightyellow sophora root and 10 parts of alum.

(1) preparing formula materials, preparing an aluminum pot for later use, putting purslane, longhairy antenoron herb, discolor cinquefoil herb, Chinese violet, honeysuckle stem, giant knotweed rhizome, common cnidium fruit, lightyellow sophora root, szechwan chinaberry fruit and alum into a grinding machine, crushing, sieving by a 100-mesh sieve, and filling the granular mixture into a non-woven bag;

(2) putting the purslane, the longhairy antenoron herb, the discolor cinquefoil herb, the Chinese violet, the honeysuckle stem, the tiger cane, the common cnidium fruit, the lightyellow sophora root, the szechwan chinaberry fruit and the alum material in parts by weight into an aluminum pot, adding 7000 ml of water into the aluminum pot for decoction, soaking the raw materials for 4 hours, then adding the water into the aluminum pot for decoction for 2 times, boiling the raw materials with strong fire, slowly decocting the raw materials with slow fire for 70min each time; after the decoction is finished, filtering the decoction to obtain filtrate and filter residue;

(3) adding Borneolum Syntheticum, heating for 30 min to obtain medicated bath liquid, and collecting the liquid.

Example 2

A medicated bath formula for adjuvant therapy of herpes zoster comprises the following active ingredients in parts by weight: 30 parts of purslane, 30 parts of lysimachia christinae hance, 30 parts of discolor cinquefoil herb, 30 parts of Chinese violet, 25 parts of honeysuckle stem, 20 parts of giant knotweed rhizome, 20 parts of borneol, 25 parts of szechwan chinaberry fruit, 15 parts of common cnidium fruit, 15 parts of lightyellow sophora root and 15 parts of alum.

(1) preparing formula materials, preparing an aluminum pot for later use, putting purslane, longhairy antenoron herb, discolor cinquefoil herb, Chinese violet, honeysuckle stem, giant knotweed rhizome, common cnidium fruit, lightyellow sophora root, szechwan chinaberry fruit and alum into a grinding machine, crushing, sieving by a 150-mesh sieve, and filling the granular mixture into a non-woven bag;

(2) putting the purslane, the longhairy antenoron herb, the discolor cinquefoil herb, the philippine violet herb, the honeysuckle stem, the tiger cane, the common cnidium fruit, the lightyellow sophora root, the szechwan chinaberry fruit and the alum material in parts by weight into an aluminum pot, adding 8000 ml of water, decocting, soaking the raw materials for 6 hours, then adding water, decocting for 2 times, boiling with strong fire, slowly decocting with slow fire for 90min each time; after the decoction is finished, filtering the decoction to obtain filtrate and filter residue;

(3) adding Borneolum Syntheticum, heating for 40 min to obtain medicated bath liquid, and collecting the liquid.

Example 3

A medicated bath formula for adjuvant therapy of herpes zoster comprises the following active ingredients in parts by weight: 35 parts of purslane, 35 parts of lysimachia, 35 parts of discolor cinquefoil herb, 35 parts of Chinese violet, 30 parts of honeysuckle stem, 25 parts of giant knotweed rhizome, 25 parts of borneol, 30 parts of szechwan chinaberry fruit, 20 parts of common cnidium fruit, 20 parts of lightyellow sophora root and 20 parts of alum.

(1) preparing formula materials, preparing an aluminum pot for later use, putting purslane, longhairy antenoron herb, discolor cinquefoil herb, Chinese violet, honeysuckle stem, giant knotweed rhizome, common cnidium fruit, lightyellow sophora root, szechwan chinaberry fruit and alum into a grinding machine, crushing, sieving by a 200-mesh sieve, and filling the granular mixture into a non-woven bag;

(2) putting the purslane, the longhairy antenoron herb, the discolor cinquefoil herb, the philippine violet herb, the honeysuckle stem, the tiger cane, the common cnidium fruit, the lightyellow sophora root, the szechwan chinaberry fruit and the alum into an aluminum pot, adding 9000 ml of water into the aluminum pot for decoction, soaking the raw materials for 8 hours, then adding the water into the aluminum pot for decoction for 3 times, boiling the raw materials with strong fire, and slowly decocting the raw materials with slow fire for 120min each time; after the decoction is finished, filtering the decoction to obtain filtrate and filter residue;

(3) adding Borneolum Syntheticum, heating for 50 min to obtain medicated bath liquid, and collecting the medicated bath liquid.

Test examples

100 patients for herpes zoster consultation were selected as study subjects between 3-6 months in 2021, wherein 25 males and 25 females were 25 and aged 15-70 years, and 100 patients were divided into 5 groups at random, wherein the experimental groups 1-3 used the medicated bath liquids prepared in examples 1-3, respectively, and were washed warm with one dose per day. The experimental group 4 uses ribavirin, the using method refers to the specification, the comparative example 1 is a blank group, no medicament is used, and the blister position of herpes is subjected to a double-diagnosis after 7 days, wherein the clinical symptoms are obviously improved to be obvious effect, the clinical symptoms are slightly improved to be effective, the clinical symptoms are not changed into ineffective, and the total effective rate is (the number of the obvious effects plus the number of the effective effects)/the total number of people. The therapeutic effect is shown in the table.

As can be seen from the table, compared with the experimental group 4 (ribavirin), the ointments prepared in the embodiments 1 to 3 of the present invention still have a higher effective rate, which indicates that the embodiments of the present invention have a good therapeutic effect on treatment of herpes zoster.

In conclusion, according to the medicated bath formula for adjuvant therapy of herpes zoster and the preparation method, purslane, longhairy antenoron herb, potentilla discolor, Chinese violet, honeysuckle stem, giant knotweed rhizome, borneol, szechwan chinaberry fruit, common cnidium fruit, lightyellow sophora root and alum are used as raw materials to prepare the traditional Chinese medicine medicated bath liquid, the wound surface can be rapidly converged aiming at the herpes zoster, so that local spreading is controlled, scabbing and healing of a sore are promoted, the course of disease is effectively shortened, pain of a patient is relieved, the preparation method is simple, the operation can be independent, and the medicated bath liquid can be used as a medicated bath fumigation and washing prescription for dermatology, and is worthy of clinical popularization and use.

In the description herein, references to the description of "one embodiment," "an example," "a specific example" or the like are intended to mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The preferred embodiments of the invention disclosed above are intended to be illustrative only. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise embodiments disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best utilize the invention. The invention is limited only by the claims and their full scope and equivalents.

Claims

1. The medicated bath formula for adjuvant therapy of herpes zoster is characterized by comprising the following active ingredients in parts by weight: 25-35 parts of purslane, 25-35 parts of lysimachia christinae hance, 25-35 parts of potentilla discolor, 25-35 parts of Chinese violet, 20-30 parts of honeysuckle stem, 15-25 parts of giant knotweed, 15-25 parts of borneol, 20-30 parts of szechwan chinaberry fruit, 10-20 parts of common cnidium fruit, 10-20 parts of radix sophorae flavescentis and 10-20 parts of alum.

2. The medicated bath formula for adjuvant therapy of herpes zoster according to claim 1, wherein the active ingredients comprise, by weight: 30 parts of purslane, 30 parts of lysimachia christinae hance, 30 parts of discolor cinquefoil herb, 30 parts of Chinese violet, 25 parts of honeysuckle stem, 20 parts of giant knotweed rhizome, 20 parts of borneol, 25 parts of szechwan chinaberry fruit, 15 parts of common cnidium fruit, 15 parts of lightyellow sophora root and 15 parts of alum.

3. A preparation method of a medicated bath formula for adjuvant therapy of herpes zoster is characterized by comprising the following steps;

(1) preparing formula materials and an aluminum pot for later use;

(2) putting the purslane, the longhairy antenoron herb, the potentilla discolor, the Chinese violet, the honeysuckle stem, the giant knotweed rhizome, the common cnidium fruit, the lightyellow sophora root, the szechwan chinaberry fruit and the alum material which are weighed according to parts by weight into an aluminum pot, adding 7000-9000 ml of water, and decocting;

4. The preparation method of the medicated bath formula for adjuvant therapy of herpes zoster according to claim 3, wherein in the step (1), purslane, longhairy antenoron herb, potentilla discolor, Chinese violet, honeysuckle stem, giant knotweed rhizome, common cnidium fruit, lightyellow sophora root, szechwan chinaberry fruit and alum are placed into a grinding machine to be smashed, screened through a 100-200-mesh sieve, and the granular mixture is filled into a non-woven bag.

5. The preparation method of the medicated bath formula for adjuvant therapy of herpes zoster according to claim 3, wherein in the step (2), the raw materials are soaked for 4-8 h, and then are decocted for 2-3 times by adding water, and the raw materials are boiled with strong fire and slowly decocted with slow fire, and each time of decoction is 70-120 min; after the decoction is finished, filtering the decoction to obtain filtrate and filter residue.

6. The preparation method of the medicated bath formula for the adjuvant treatment of herpes zoster according to claim 3, wherein in the step (3), the borneol is dissolved in water completely.