CN114099603A - Edible itching-relieving ointment for mosquito bites - Google Patents

Edible itching-relieving ointment for mosquito bites Download PDF

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Publication number
CN114099603A
CN114099603A CN202010892354.7A CN202010892354A CN114099603A CN 114099603 A CN114099603 A CN 114099603A CN 202010892354 A CN202010892354 A CN 202010892354A CN 114099603 A CN114099603 A CN 114099603A
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CN
China
Prior art keywords
parts
itching
edible
mosquito bites
relieving ointment
Prior art date
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Pending
Application number
CN202010892354.7A
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Chinese (zh)
Inventor
杜滴儿
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Individual
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Individual
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Priority to CN202010892354.7A priority Critical patent/CN114099603A/en
Publication of CN114099603A publication Critical patent/CN114099603A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention provides an edible itching relieving ointment for mosquito bites, which belongs to the technical field of itching relieving ointment and is prepared from the following raw materials in parts by weight: 1-3 parts of edible glycerol, 1-4 parts of xanthan gum, 2-6 parts of sodium chloride, 1-3 parts of aloe-emodin, 1-3 parts of aloe tincture, 1-3 parts of isoaloesin, 1-3 parts of glycopeptide mannan Ke-2 and 1-2 parts of tocopheryl acetate; the itching relieving ointment has good itching relieving effect on mosquito bites, can be directly applied to the mosquito bites to relieve itching within three seconds, can reduce swelling within ten to twenty minutes, and does not leave scars; belongs to food-grade antipruritic products, and is safer for infants and adults to use.

Description

Edible itching-relieving ointment for mosquito bites
Technical Field
The invention relates to the technical field of itching relieving paste, in particular to edible itching relieving paste for mosquito bites.
Background
The existing itching relieving ointment for mosquito bites has slow effect, contains a large amount of chemical additives, has serious damage to the health of a human body after being eaten by mistake, and is inconvenient for infants to use.
Disclosure of Invention
Aiming at the technical defects, the invention aims to provide the edible itching-relieving ointment for mosquito bites, which has good itching-relieving effect on mosquito bites, can be directly applied to mosquito bites to relieve itching for three seconds, can relieve swelling for ten to twenty minutes and does not leave scars: belongs to food-grade antipruritic products, and is safer for infants and adults to use.
In order to achieve the purpose, the technical scheme of the invention is as follows:
an edible itching relieving ointment for mosquito bites is characterized by being prepared from the following raw materials in parts by weight:
1-3 parts of edible glycerol, 1-4 parts of xanthan gum, 2-6 parts of sodium chloride, 1-3 parts of aloe-emodin, 1-3 parts of aloe tincture, 1-3 parts of isoaloesin, 1-3 parts of glycopeptide mannan Ke-2 and 1-2 parts of tocopheryl acetate.
The invention has the beneficial effects that: the itching relieving ointment has good itching relieving effect on mosquito bites, can be directly applied to the mosquito bites to relieve itching within three seconds, can reduce swelling within ten to twenty minutes, and does not leave scars; belongs to food-grade antipruritic products, and is safer for infants and adults to use.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
An edible itching relieving ointment for mosquito bites is prepared from the following raw materials in parts by weight:
2 grams of edible glycerin, 3 grams of xanthan gum, 5 grams of sodium chloride, 2 grams of aloe-emodin, 2 grams of aloe tincture, 2 grams of isoaloesin, 2 grams of glycopeptide mannan Ke-2, and 1 gram of tocopheryl acetate.
The preparation method comprises the following steps:
mixing edible glycerol, aloe-emodin, aloe tincture, isoaloesin, polypeptide mannan Ke-2, and tocopheryl acetate at a certain proportion, adding xanthan gum, stirring, and immediately adding sodium chloride, and stirring; this work was done in 10 seconds and then continued with stirring until all the salt particles were soaked.
Example 2
An edible itching relieving ointment for mosquito bites is prepared from the following raw materials in parts by weight:
3 grams of edible glycerin, 2 grams of xanthan gum, 3 grams of sodium chloride, 1 gram of aloe-emodin, 3 grams of aloe tincture, 2 grams of isoaloesin, 3 grams of glycopeptide mannan Ke-2, and 2 grams of tocopheryl acetate.
The preparation method is the same as that of example 1.
Experimental group 1
60 mice which are bitten by mosquitoes and have different degrees of red and swollen phenomena at the bitten positions are selected, the itching relieving ointment prepared in the embodiment 1 or 2 is smeared, 16 mice can be killed within 10 minutes, 42 mice can be killed within 10 to 20 minutes, and 2 mice have no obvious effect;
the effect is shown: the swelling can be reduced within 10 minutes, and the obvious effect rate is 26.7 percent;
the method has the following advantages: the swelling can be relieved within 20 minutes, and the effective rate is 96.7 percent.
Experimental group 2
50 volunteers of all ages bitten by mosquitoes are selected, the bitten parts have itching and red swelling phenomena with different degrees, the itching relieving ointment prepared in the embodiment 1 or 2 is smeared, and 50 people can relieve itching within three seconds; the number of the detumescence is 12 within 10 minutes, the number of the detumescence is 35 within 10 to 20 minutes, and 3 people have no obvious effect;
the effective rate of relieving itching is 100 percent;
the detumescence efficiency is 24%:
the effective rate of detumescence is 94%.
Toxicity test experiment
20 healthy mice are selected and fed with the itching relieving cream prepared in the embodiment 1 or 2 respectively, and are cultured normally and observed for one week, and all the mice are normal and have no adverse reaction or death phenomenon.
In conclusion, the itching relieving ointment has good itching relieving effect on mosquito bites, can relieve itching after being directly applied to the mosquito bites for three seconds, can reduce swelling in ten to twenty minutes, and does not leave scars; belongs to food-grade antipruritic products, and is safer for infants and adults to use.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (1)

1. An edible itching relieving ointment for mosquito bites is characterized by being prepared from the following raw materials in parts by weight:
1-3 parts of edible glycerol, 1-4 parts of xanthan gum, 2-6 parts of sodium chloride, 1-3 parts of aloe-emodin, 1-3 parts of aloe tincture, 1-3 parts of isoaloesin, 1-3 parts of glycopeptide mannan Ke-2 and 1-2 parts of tocopheryl acetate.
CN202010892354.7A 2020-08-25 2020-08-25 Edible itching-relieving ointment for mosquito bites Pending CN114099603A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010892354.7A CN114099603A (en) 2020-08-25 2020-08-25 Edible itching-relieving ointment for mosquito bites

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010892354.7A CN114099603A (en) 2020-08-25 2020-08-25 Edible itching-relieving ointment for mosquito bites

Publications (1)

Publication Number Publication Date
CN114099603A true CN114099603A (en) 2022-03-01

Family

ID=80359776

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010892354.7A Pending CN114099603A (en) 2020-08-25 2020-08-25 Edible itching-relieving ointment for mosquito bites

Country Status (1)

Country Link
CN (1) CN114099603A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494725A (en) * 2013-07-17 2014-01-08 吴克 Aloe gel for inflammation diminishing and skin care

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103494725A (en) * 2013-07-17 2014-01-08 吴克 Aloe gel for inflammation diminishing and skin care

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
姚立华等: "芦荟活性成分的生物学作用研究进展", 《科技通报》 *
张崇亮: "夏秋蚊虫咬 芦荟不可少", 《中国花卉盆景》 *
郭彦萍: "芦荟蜂胶酊治疗复发性口疮的临床疗效观察", 《白求恩医科大学学报》 *

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Application publication date: 20220301

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