CN114032283A - 一种肠癌检测试剂及其在肠癌检测中的应用 - Google Patents

一种肠癌检测试剂及其在肠癌检测中的应用 Download PDF

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Publication number
CN114032283A
CN114032283A CN202111080500.7A CN202111080500A CN114032283A CN 114032283 A CN114032283 A CN 114032283A CN 202111080500 A CN202111080500 A CN 202111080500A CN 114032283 A CN114032283 A CN 114032283A
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Prior art keywords
reagent
intestinal cancer
cancer detection
detection reagent
concentration
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Pending
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CN202111080500.7A
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English (en)
Chinese (zh)
Inventor
陈翠英
王蕾
谈宗男
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Jiangsu Xiansida Biotechnology Co ltd
Xiansida Nanjing Biotechnology Co ltd
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Priority to CN202111080500.7A priority Critical patent/CN114032283A/zh
Publication of CN114032283A publication Critical patent/CN114032283A/zh
Priority to PCT/CN2022/118798 priority patent/WO2023040911A1/fr
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
    • G01N2440/38—Post-translational modifications [PTMs] in chemical analysis of biological material addition of carbohydrates, e.g. glycosylation, glycation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN202111080500.7A 2021-09-15 2021-09-15 一种肠癌检测试剂及其在肠癌检测中的应用 Pending CN114032283A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202111080500.7A CN114032283A (zh) 2021-09-15 2021-09-15 一种肠癌检测试剂及其在肠癌检测中的应用
PCT/CN2022/118798 WO2023040911A1 (fr) 2021-09-15 2022-09-14 Réactif de détection du carcinome du rectum et son application dans la détection du carcinome du rectum

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202111080500.7A CN114032283A (zh) 2021-09-15 2021-09-15 一种肠癌检测试剂及其在肠癌检测中的应用

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CN114032283A true CN114032283A (zh) 2022-02-11

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CN202111080500.7A Pending CN114032283A (zh) 2021-09-15 2021-09-15 一种肠癌检测试剂及其在肠癌检测中的应用

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CN (1) CN114032283A (fr)
WO (1) WO2023040911A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023040911A1 (fr) * 2021-09-15 2023-03-23 江苏先思达生物科技有限公司 Réactif de détection du carcinome du rectum et son application dans la détection du carcinome du rectum

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WO2008152070A1 (fr) * 2007-06-14 2008-12-18 Vib Vzw Test diagnostique pour la détection d'un cancer du foie à un stade précoce
CN101576495A (zh) * 2009-06-09 2009-11-11 中国人民解放军第二军医大学 一种检测血清N糖log(P9/P4)的方法、检测系统及其应用
US20090311707A1 (en) * 2008-06-17 2009-12-17 Lijun Xia O-glycans as diagnostic markers for inflammatory bowel disease
CN102565318A (zh) * 2012-01-11 2012-07-11 陈翠英 一种肝癌监测、分期以及预后风险评估的试剂及其方法
WO2017032888A1 (fr) * 2015-08-26 2017-03-02 Vib Vzw Moyens et méthodes de surveillance de l'inflammation
CN106814121A (zh) * 2015-11-30 2017-06-09 中国科学院大连化学物理研究所 一种基于微流控芯片的血清糖谱分型方法
CN107894483A (zh) * 2017-06-20 2018-04-10 江苏先思达生物科技有限公司 肝衰竭的血清糖蛋白n‑糖组图谱模型的建立方法
CN110261495A (zh) * 2018-11-01 2019-09-20 青岛大学附属医院 一种鉴定结直肠癌症生物标记物的方法及其检测试剂盒

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CN106950379B (zh) * 2017-03-02 2019-01-22 江苏先思达生物科技有限公司 一种肺癌监测试剂盒及其使用方法
CN106950380B (zh) * 2017-03-02 2019-01-11 江苏先思达生物科技有限公司 一种胃癌监测试剂盒及其使用方法
CN109100507A (zh) * 2017-06-20 2018-12-28 江苏先思达生物科技有限公司 慢性肝炎肝损伤的血清糖蛋白n-糖组图谱模型的建立方法
CN109100410B (zh) * 2017-06-20 2020-11-13 江苏先思达生物科技有限公司 肝硬化的血清糖蛋白n-糖组图谱模型的建立方法
CN109682974A (zh) * 2018-12-29 2019-04-26 江苏先思达生物科技有限公司 一种胰腺癌检测试剂及其在胰腺癌检测中的应用
CN114032283A (zh) * 2021-09-15 2022-02-11 陈翠英 一种肠癌检测试剂及其在肠癌检测中的应用

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008152070A1 (fr) * 2007-06-14 2008-12-18 Vib Vzw Test diagnostique pour la détection d'un cancer du foie à un stade précoce
US20090311707A1 (en) * 2008-06-17 2009-12-17 Lijun Xia O-glycans as diagnostic markers for inflammatory bowel disease
CN101576495A (zh) * 2009-06-09 2009-11-11 中国人民解放军第二军医大学 一种检测血清N糖log(P9/P4)的方法、检测系统及其应用
CN102565318A (zh) * 2012-01-11 2012-07-11 陈翠英 一种肝癌监测、分期以及预后风险评估的试剂及其方法
WO2017032888A1 (fr) * 2015-08-26 2017-03-02 Vib Vzw Moyens et méthodes de surveillance de l'inflammation
CN106814121A (zh) * 2015-11-30 2017-06-09 中国科学院大连化学物理研究所 一种基于微流控芯片的血清糖谱分型方法
CN107894483A (zh) * 2017-06-20 2018-04-10 江苏先思达生物科技有限公司 肝衰竭的血清糖蛋白n‑糖组图谱模型的建立方法
CN110261495A (zh) * 2018-11-01 2019-09-20 青岛大学附属医院 一种鉴定结直肠癌症生物标记物的方法及其检测试剂盒

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Title
YIQING PAN等: "Screening and diagnosis of colorectal cancer and advanced adenoma by Bionic Glycome method and machine learning", AM J CANCER RES, vol. 11, no. 6, pages 3002 - 3020 *
徐昕昀;赵云鹏;阮灿平;高文超;王治国;高春芳;: "建立并评估新的胃癌N-糖诊断标志物", 现代免疫学, no. 03, pages 213 - 218 *
舒健;于汉杰;刘夏薇;张旦旦;李铮;: "胃癌相关糖蛋白糖链谱的研究进展", 生物化学与生物物理进展, vol. 43, no. 05, pages 449 - 460 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023040911A1 (fr) * 2021-09-15 2023-03-23 江苏先思达生物科技有限公司 Réactif de détection du carcinome du rectum et son application dans la détection du carcinome du rectum

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