CN113985043A - Thrombelastogram instrument - Google Patents

Thrombelastogram instrument Download PDF

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Publication number
CN113985043A
CN113985043A CN202111253058.3A CN202111253058A CN113985043A CN 113985043 A CN113985043 A CN 113985043A CN 202111253058 A CN202111253058 A CN 202111253058A CN 113985043 A CN113985043 A CN 113985043A
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China
Prior art keywords
module
needle
sampling
liquid
pipetting
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Pending
Application number
CN202111253058.3A
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Chinese (zh)
Inventor
唐宇阳
孙亚威
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Yangpu Medical Technology Co ltd
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Hepis Technology Shenzhen Co ltd
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Priority to CN202111253058.3A priority Critical patent/CN113985043A/en
Publication of CN113985043A publication Critical patent/CN113985043A/en
Pending legal-status Critical Current

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004Cleaning sample transfer devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Robotics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

The invention relates to a thromboelastogram instrument, which comprises a thromboelastogram detection module for detecting a thromboelastogram project, an activation tube tray for placing activation tubes, a cup tray for placing reaction cups, a reagent bottle module, a sampling module for sampling blood, a liquid transfer module for transferring liquid and moving the reaction cups, and a cleaning module; the sampling module comprises a sampling needle, the liquid transfer module comprises a liquid transfer needle, the cleaning module comprises a sampling needle cleaning module for cleaning the sampling needle, a liquid transfer needle cleaning module for cleaning the liquid transfer needle and a liquid path module, and the sampling needle cleaning module and the liquid transfer needle cleaning module are both communicated with and controlled by the liquid path module; the thrombelastogram instrument has the advantages that the thrombelastogram instrument is good in integrity, high in function modularization degree and concise in combination assembly, the detection modules in different numbers can be matched according to actual demands to meet the demands of different hospitals, and space saving and automatic detection are facilitated.

Description

Thrombelastogram instrument
Technical Field
The invention relates to the technical field of medical instruments, in particular to a thromboelastogram instrument.
Background
There are three types of conventional thromboelastography devices: the first type is a manual instrument, almost no automation exists, the operation is complex, and the labor intensity of a doctor is extremely high; the second type is a semi-automatic thrombelastogram instrument, which is more in the market at present and is slightly simpler to operate than a manual one, but the problems of high labor intensity, inconvenience in operation and the like still exist when large-sample-volume detection is carried out; the third type is full-automatic thrombelastogram appearance, and this type of instrument on the existing market has solved manual operation's trouble, but the structure sets up comparatively complicatedly, and the detection channel number is less, and the great clinical laboratory of being not convenient for of volume is put.
Disclosure of Invention
The invention aims to solve the technical problem of providing a thrombelastogram instrument aiming at the defects of the prior art.
The technical scheme adopted by the invention for solving the technical problems is as follows:
constructing a thromboelastogram instrument, wherein the thromboelastogram instrument comprises a thromboelastogram detection module for detecting thromboelastogram items, an activation tube tray for placing activation tubes, a cup tray for placing reaction cups, a reagent bottle module, a sampling module for sampling blood, a pipetting module for pipetting and moving the reaction cups, and a cleaning module; the sampling module includes the sampling needle, it includes the pipetting needle to move the liquid module, it includes right to wash the module, right to move the abluent sampling needle of liquid needle the abluent pipetting needle of pipetting needle washs module and liquid way module, the sampling needle wash module with move the liquid needle wash module all with liquid way module UNICOM receives its control.
The thrombelastogram instrument further comprises a frame, the thrombelastogram detection module is arranged on the rear side of the frame, and the activation tube disc and the cup disc are arranged on the front side of the frame; the liquid-transfering module is arranged above the cup tray.
The thrombelastogram instrument provided by the invention is characterized in that the rack is divided into an upper layer and a lower layer, the thrombelastogram detection module, the activation tube disc and the cup disc are mounted on the upper layer of the rack, and the liquid path module is mounted on the lower layer of the rack.
The invention provides a thrombelastogram instrument, wherein a plurality of thrombelastogram detection modules are arranged on the rack side by side.
The invention relates to a thrombelastogram instrument, wherein the sampling module further comprises a sampling mechanical arm driving the sampling needle to move and a first plunger pump communicated with the sampling needle.
The invention provides a thrombelastogram instrument, wherein the thrombelastogram instrument further comprises a discard reaction cup discard port.
The thrombelastogram instrument provided by the invention comprises a reaction cup, a liquid transferring needle and a liquid transferring module, wherein the reaction cup is arranged in the reaction cup, and the liquid transferring needle is driven by the liquid transferring manipulator to move.
The invention relates to a thrombelastogram instrument, wherein a second plunger pump communicated with a liquid-transferring needle is further arranged at the movable end of the liquid-transferring mechanical hand.
The invention also provides a thrombelastogram instrument, wherein the thrombelastogram instrument further comprises a transverse moving unit which drives the activation tube disc to transversely move.
The thrombelastogram instrument provided by the invention is characterized in that a refrigerating unit for refrigerating the reaction cup is arranged on the cup disc.
The invention has the beneficial effects that: during detection, after the sampling module quantitatively collects blood from a blood test tube, the blood is added into an activation tube on an activation tube tray for activation, the pipetting module clamps a reaction cup from the cup tray and then places the reaction cup on a detection station of the thromboelastogram detection module, then the pipetting module respectively drives a pipetting needle to quantitatively suck the blood in the activation tube, a reagent in the reagent cup on the cup tray or a reagent in a reagent bottle on the reagent bottle module and add the reagent into the reaction cup of the thromboelastogram detection module, the thromboelastogram detection module detects thromboelastogram items, and the sampling needle and the pipetting needle are automatically cleaned by the cleaning module correspondingly after each use; the thrombelastogram instrument has the advantages that the thrombelastogram instrument is good in integrity, high in function modularization degree and concise in combination assembly, the detection modules in different numbers can be matched according to actual demands to meet the demands of different hospitals, and space saving and automatic detection are facilitated.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the present invention will be further described with reference to the accompanying drawings and embodiments, wherein the drawings in the following description are only part of the embodiments of the present invention, and for those skilled in the art, other drawings can be obtained without inventive efforts according to the accompanying drawings:
FIG. 1 is a schematic structural view of a thrombelastogram apparatus according to a preferred embodiment of the present invention;
figure 2 is a top view of a thrombelastogram apparatus according to a preferred embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the following will clearly and completely describe the technical solutions in the embodiments of the present invention, and it is obvious that the described embodiments are some embodiments of the present invention, but not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present invention without inventive step, are within the scope of the present invention.
Referring to fig. 2, the thromboelastogram apparatus according to the preferred embodiment of the present invention, as shown in fig. 1, includes a thromboelastogram detection module 1 for performing thromboelastogram item detection, an activation tube tray 2 for placing activation tubes, a cup tray 3 for placing reaction cups, a reagent bottle module 4, a sampling module 5 for performing blood sampling, a pipetting module 6 for performing pipetting and moving reaction cups, and a cleaning module 7; the sampling module 5 comprises a sampling needle 50, the pipetting module 6 comprises a pipetting needle 60, the cleaning module 7 comprises a sampling needle 50 cleaning module 70 for cleaning the sampling needle, a pipetting needle cleaning module 71 for cleaning the pipetting needle 60 and a liquid path module 72, and the sampling needle cleaning module 70 and the pipetting needle cleaning module 71 are both communicated with and controlled by the liquid path module 72;
during detection, after the sampling module 5 quantitatively collects blood from a blood test tube, the blood is added into an activation tube on an activation tube tray 2 for activation, the liquid transfer module 6 clamps a reaction cup from the cup tray 3 and then places the reaction cup on a detection station of the thromboelastogram detection module 1, then the liquid transfer module 6 respectively drives a liquid transfer needle 60 to quantitatively absorb the blood in the activation tube, reagents in the reaction cup on the cup tray 3 or reagents in a reagent bottle module 4 onto the reaction cup of the thromboelastogram detection module 1 (corresponding cleaning is needed after each absorption), the thromboelastogram detection module 1 carries out thromboelastogram item detection, and the sampling needle 50 and the liquid transfer needle 60 are automatically cleaned by a cleaning module 7 after each use;
the thrombelastogram instrument has the advantages that the integrality is good, the degree of modularization of each function is high, the combination and assembly are simpler, the detection channels with different numbers can be matched according to actual requirements to meet the requirements of different hospitals, the space is saved, and automatic detection is realized;
it should be noted that the thrombelastogram appearance of this application does not contain (blood test tube) sampling device, can select to coordinate the sample platform or manual appearance of advancing when using.
Preferably, the reagent bottle module 4 is arranged in a position between the activation tube tray 2 and the cup tray 3;
preferably, the thrombelastogram instrument further comprises a frame 8, the thrombelastogram detection module 1 is arranged on the rear side of the frame 8, and the activation tube tray 2 and the cup tray 3 are both arranged on the front side of the frame 8; the liquid-transfering module 6 is arranged above the cup plate 3; the layout is reasonable and compact, and the manual intervention and the state monitoring are convenient.
Preferably, the rack 8 is divided into an upper layer and a lower layer, the upper layer of the rack 8 is provided with the thromboelastogram detection module 1, the activation tube tray 2 and the cup tray 3, and the lower layer of the rack 8 is provided with the liquid path module 72; reasonable layout and good integrity.
Preferably, a plurality of thromboelastogram detection modules 1 are arranged on the frame 8 side by side; and the multi-station thrombus detection is convenient.
Preferably, the sampling module 5 further includes a sampling manipulator 51 driving the sampling needle 50 to move and a first plunger pump 52 communicated with the sampling needle 50; the control is easy, and the sampling manipulator 51 and the first plunger pump can be realized by the existing equipment.
Preferably, the thromboelastography device also comprises a waste reaction cup discarding port 9; the reaction cup on the thromboelastogram detection module 1 after detection is convenient to discard; preferably, the cuvette disposal port 9 is arranged at a position between the activation tube tray 2 and the cup tray 3.
Preferably, the pipetting module 6 further comprises a pipetting manipulator 61 and a clamping jaw 62 for clamping the reaction cup, and the clamping jaw 62 and the pipetting needle 60 are driven by the pipetting manipulator 61 to move; the pipetting manipulator 61 and the clamping jaw 62 can sample the existing equipment; during installation, the interference can be avoided by a mode that one or two of the clamping jaw 62 and the pipetting needle 60 are driven by a mode that a lifting cylinder and the like are arranged on the manipulator, and the interference can also be avoided by a mode that the transverse distance between the clamping jaw 62 and the pipetting needle 60 is controlled.
Preferably, the movable end of the pipetting robot 61 is further provided with a second plunger pump 63 in communication with the pipetting needle 60.
Preferably, the thromboelastography instrument also comprises a traverse unit 10 for driving the activation tube disc 2 to traverse; the sampling of the mechanical hand of sampling of being convenient for cooperation promotes sampling efficiency.
Preferably, a refrigerating unit for refrigerating the reaction cup is arranged on the cup plate 3; the reagent is convenient to store for a long time.
It will be understood that modifications and variations can be made by persons skilled in the art in light of the above teachings and all such modifications and variations are intended to be included within the scope of the invention as defined in the appended claims.

Claims (10)

1. The thromboelastogram instrument is characterized by comprising a thromboelastogram detection module for detecting thromboelastogram items, an activation tube tray for placing activation tubes, a cup tray for placing reaction cups, a reagent bottle module, a sampling module for sampling blood, a liquid transfer module for transferring liquid and moving the reaction cups, and a cleaning module; the sampling module includes the sampling needle, it includes the pipetting needle to move the liquid module, it includes right to wash the module, right to move the abluent sampling needle of liquid needle the abluent pipetting needle of pipetting needle washs module and liquid way module, the sampling needle wash module with move the liquid needle wash module all with liquid way module UNICOM receives its control.
2. The thromboelastography device of claim 1, further comprising a frame, the thromboelastography detection module being disposed on a rear side of the frame, the activation tube tray and the cup tray both being disposed on a front side of the frame; the liquid-transfering module is arranged above the cup tray.
3. The apparatus according to claim 2, wherein the frame is divided into an upper layer and a lower layer, the upper layer of the frame is provided with the thromboelastogram detection module, the activation tube tray and the cup tray, and the lower layer of the frame is provided with the liquid path module.
4. The thromboelastography device of claim 2, wherein the thromboelastography detection module is arranged in plurality side by side on the frame.
5. The apparatus of claim 1, wherein the sampling module further comprises a sampling manipulator that moves the sampling needle and a first plunger pump in communication with the sampling needle.
6. The thromboelastography device of claim 1, further comprising an discard cuvette discard port.
7. The apparatus according to claim 1, wherein the pipetting module further comprises a pipetting robot and a gripper for gripping the reaction cup, and the gripper and the pipetting needle are moved by the pipetting robot.
8. The apparatus according to claim 7, wherein the movable end of the pipetting robot is further provided with a second plunger pump in communication with the pipetting needle.
9. The thromboelastography device of claim 1, further comprising a traverse unit that traverses the activation tube disk.
10. The apparatus according to claim 1, wherein a cooling unit for cooling the reaction cup is provided on the cup tray.
CN202111253058.3A 2021-10-27 2021-10-27 Thrombelastogram instrument Pending CN113985043A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202111253058.3A CN113985043A (en) 2021-10-27 2021-10-27 Thrombelastogram instrument

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Application Number Priority Date Filing Date Title
CN202111253058.3A CN113985043A (en) 2021-10-27 2021-10-27 Thrombelastogram instrument

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CN113985043A true CN113985043A (en) 2022-01-28

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115372603A (en) * 2022-07-15 2022-11-22 深圳沃德生命科技有限公司 Thrombus elastogram analyzer and using method thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1384361A (en) * 2001-04-27 2002-12-11 刘岩 Separate multi-channel biochemical analyzer
CN108414737A (en) * 2018-06-13 2018-08-17 安徽为臻生物工程技术有限公司 A kind of Full-automatic chemiluminescence immunoassay analysis meter
CN111735978A (en) * 2020-01-12 2020-10-02 南京岚煜生物科技有限公司 Full-automatic chemiluminescence immunoassay analyzer
CN212646715U (en) * 2020-06-12 2021-03-02 山东新华医疗器械股份有限公司 Full-automatic analyzer
CN113219188A (en) * 2021-04-25 2021-08-06 深圳沃德生命科技有限公司 Integrated modular structure and equipment for thrombus elasticity and blood coagulation analysis
CN113406346A (en) * 2021-07-08 2021-09-17 成都艾科斯伦医疗科技有限公司 Blood sample analyzer
CN113504380A (en) * 2021-06-15 2021-10-15 复星诊断科技(上海)有限公司 Full-automatic chemiluminescence immunoassay analyzer

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1384361A (en) * 2001-04-27 2002-12-11 刘岩 Separate multi-channel biochemical analyzer
CN108414737A (en) * 2018-06-13 2018-08-17 安徽为臻生物工程技术有限公司 A kind of Full-automatic chemiluminescence immunoassay analysis meter
CN111735978A (en) * 2020-01-12 2020-10-02 南京岚煜生物科技有限公司 Full-automatic chemiluminescence immunoassay analyzer
CN212646715U (en) * 2020-06-12 2021-03-02 山东新华医疗器械股份有限公司 Full-automatic analyzer
CN113219188A (en) * 2021-04-25 2021-08-06 深圳沃德生命科技有限公司 Integrated modular structure and equipment for thrombus elasticity and blood coagulation analysis
CN113504380A (en) * 2021-06-15 2021-10-15 复星诊断科技(上海)有限公司 Full-automatic chemiluminescence immunoassay analyzer
CN113406346A (en) * 2021-07-08 2021-09-17 成都艾科斯伦医疗科技有限公司 Blood sample analyzer

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115372603A (en) * 2022-07-15 2022-11-22 深圳沃德生命科技有限公司 Thrombus elastogram analyzer and using method thereof

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Effective date of registration: 20220721

Address after: 519000 office 2320, No. 3000, Huandao East Road, Hengqin New District, Zhuhai City, Guangdong Province

Applicant after: Yangpu Medical Technology Co.,Ltd.

Address before: 518100 b121, block A.B, Chuang Zhi Park, No. 18, Shangnan Shangliao Industrial Road, Shangliao community, Xinqiao street, Bao'an District, Shenzhen, Guangdong

Applicant before: Hepis Technology (Shenzhen) Co.,Ltd.

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