CN113930331A - 荧光免疫检测分析仪温育温度控制方法、介质、pcr检测系统 - Google Patents
荧光免疫检测分析仪温育温度控制方法、介质、pcr检测系统 Download PDFInfo
- Publication number
- CN113930331A CN113930331A CN202111176417.XA CN202111176417A CN113930331A CN 113930331 A CN113930331 A CN 113930331A CN 202111176417 A CN202111176417 A CN 202111176417A CN 113930331 A CN113930331 A CN 113930331A
- Authority
- CN
- China
- Prior art keywords
- incubation
- temperature
- heating
- module
- disc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000011534 incubation Methods 0.000 title claims abstract description 139
- 238000000034 method Methods 0.000 title claims abstract description 48
- 238000003018 immunoassay Methods 0.000 title claims abstract description 33
- 238000001514 detection method Methods 0.000 title claims abstract description 17
- 238000010438 heat treatment Methods 0.000 claims abstract description 207
- 238000006243 chemical reaction Methods 0.000 claims abstract description 59
- 230000008569 process Effects 0.000 claims abstract description 13
- 230000007246 mechanism Effects 0.000 claims description 22
- 230000008859 change Effects 0.000 claims description 9
- 238000001917 fluorescence detection Methods 0.000 claims description 9
- 238000004590 computer program Methods 0.000 claims description 5
- 238000003752 polymerase chain reaction Methods 0.000 description 21
- 239000000523 sample Substances 0.000 description 15
- 150000007523 nucleic acids Chemical class 0.000 description 13
- 108020004707 nucleic acids Proteins 0.000 description 12
- 102000039446 nucleic acids Human genes 0.000 description 12
- 241000700605 Viruses Species 0.000 description 10
- 238000012408 PCR amplification Methods 0.000 description 7
- 230000003321 amplification Effects 0.000 description 5
- 238000003199 nucleic acid amplification method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 241000711573 Coronaviridae Species 0.000 description 3
- 108091028043 Nucleic acid sequence Proteins 0.000 description 3
- 238000003384 imaging method Methods 0.000 description 3
- 238000009413 insulation Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 229920002477 rna polymer Polymers 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 2
- 102000053602 DNA Human genes 0.000 description 2
- 241000202934 Mycoplasma pneumoniae Species 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 230000004907 flux Effects 0.000 description 2
- 238000003753 real-time PCR Methods 0.000 description 2
- 238000007430 reference method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000004544 DNA amplification Effects 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 238000002795 fluorescence method Methods 0.000 description 1
- 238000010166 immunofluorescence Methods 0.000 description 1
- 238000009533 lab test Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
Images
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Clinical Laboratory Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111176417.XA CN113930331A (zh) | 2021-10-09 | 2021-10-09 | 荧光免疫检测分析仪温育温度控制方法、介质、pcr检测系统 |
PCT/CN2022/129446 WO2023056985A1 (fr) | 2021-10-09 | 2022-11-03 | Procédé de régulation de la température d'incubation pour analyseur d'immunodosage par fluorescence, et support et système de détection par pcr |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111176417.XA CN113930331A (zh) | 2021-10-09 | 2021-10-09 | 荧光免疫检测分析仪温育温度控制方法、介质、pcr检测系统 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN113930331A true CN113930331A (zh) | 2022-01-14 |
Family
ID=79278342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111176417.XA Pending CN113930331A (zh) | 2021-10-09 | 2021-10-09 | 荧光免疫检测分析仪温育温度控制方法、介质、pcr检测系统 |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN113930331A (fr) |
WO (1) | WO2023056985A1 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023056985A1 (fr) * | 2021-10-09 | 2023-04-13 | 苏州国科均豪生物科技有限公司 | Procédé de régulation de la température d'incubation pour analyseur d'immunodosage par fluorescence, et support et système de détection par pcr |
CN117511725A (zh) * | 2023-12-21 | 2024-02-06 | 北京康润诚业生物科技有限公司 | 一种酶分子定向进化生物信息分析装置及方法 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06277036A (ja) * | 1993-03-26 | 1994-10-04 | Sanyo Electric Co Ltd | インキュベータ |
US20160214112A1 (en) * | 2013-09-11 | 2016-07-28 | Osaka University | Thermal convection generating chip, thermal convection generating device, and thermal convection generating method |
CN108277149A (zh) * | 2018-06-04 | 2018-07-13 | 上海速创诊断产品有限公司 | 核酸检测装置、方法及系统 |
CN208266181U (zh) * | 2018-01-23 | 2018-12-21 | 上海速创诊断产品有限公司 | 一种用于恒温微流控芯片的核酸分析装置 |
CN110791423A (zh) * | 2019-11-15 | 2020-02-14 | 上海速创诊断产品有限公司 | 核酸检测装置、方法及系统 |
CN111197003A (zh) * | 2019-12-26 | 2020-05-26 | 中国科学院合肥物质科学研究院 | 一种基于智能手机的集成核酸提取扩增检测的分析装置及方法 |
CN111487422A (zh) * | 2019-01-28 | 2020-08-04 | 深圳市帝迈生物技术有限公司 | 时序控制方法、存储介质及样本分析仪 |
WO2021135366A1 (fr) * | 2019-12-31 | 2021-07-08 | 科美诊断技术股份有限公司 | Procédé d'agencement d'éléments de test d'échantillons et appareil |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5372418B2 (ja) * | 2008-06-23 | 2013-12-18 | 株式会社日立ハイテクノロジーズ | 核酸分析装置,自動分析装置、及び分析方法 |
WO2018235332A1 (fr) * | 2017-06-23 | 2018-12-27 | コニカミノルタ株式会社 | Dispositif de détection d'échantillon et procédé de détection d'échantillon |
CN110470854A (zh) * | 2018-05-11 | 2019-11-19 | 博阳生物科技(上海)有限公司 | 全自动免疫分析仪 |
CN208443845U (zh) * | 2018-07-23 | 2019-01-29 | 苏州长光华医生物医学工程有限公司 | 一种温育盘 |
CN112538415B (zh) * | 2020-12-23 | 2024-08-13 | 深圳市呈晖医疗科技有限公司 | 单盘式自动核酸分析装置 |
CN113930331A (zh) * | 2021-10-09 | 2022-01-14 | 苏州国科均豪生物科技有限公司 | 荧光免疫检测分析仪温育温度控制方法、介质、pcr检测系统 |
-
2021
- 2021-10-09 CN CN202111176417.XA patent/CN113930331A/zh active Pending
-
2022
- 2022-11-03 WO PCT/CN2022/129446 patent/WO2023056985A1/fr active Application Filing
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06277036A (ja) * | 1993-03-26 | 1994-10-04 | Sanyo Electric Co Ltd | インキュベータ |
US20160214112A1 (en) * | 2013-09-11 | 2016-07-28 | Osaka University | Thermal convection generating chip, thermal convection generating device, and thermal convection generating method |
CN208266181U (zh) * | 2018-01-23 | 2018-12-21 | 上海速创诊断产品有限公司 | 一种用于恒温微流控芯片的核酸分析装置 |
CN108277149A (zh) * | 2018-06-04 | 2018-07-13 | 上海速创诊断产品有限公司 | 核酸检测装置、方法及系统 |
CN111487422A (zh) * | 2019-01-28 | 2020-08-04 | 深圳市帝迈生物技术有限公司 | 时序控制方法、存储介质及样本分析仪 |
CN110791423A (zh) * | 2019-11-15 | 2020-02-14 | 上海速创诊断产品有限公司 | 核酸检测装置、方法及系统 |
CN111197003A (zh) * | 2019-12-26 | 2020-05-26 | 中国科学院合肥物质科学研究院 | 一种基于智能手机的集成核酸提取扩增检测的分析装置及方法 |
WO2021135366A1 (fr) * | 2019-12-31 | 2021-07-08 | 科美诊断技术股份有限公司 | Procédé d'agencement d'éléments de test d'échantillons et appareil |
Non-Patent Citations (1)
Title |
---|
杨延丽;: "一种适用于全自动化学发光免疫分析仪器的温育模块研究", 科技创新与应用, no. 33, pages 34 - 35 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023056985A1 (fr) * | 2021-10-09 | 2023-04-13 | 苏州国科均豪生物科技有限公司 | Procédé de régulation de la température d'incubation pour analyseur d'immunodosage par fluorescence, et support et système de détection par pcr |
CN117511725A (zh) * | 2023-12-21 | 2024-02-06 | 北京康润诚业生物科技有限公司 | 一种酶分子定向进化生物信息分析装置及方法 |
Also Published As
Publication number | Publication date |
---|---|
WO2023056985A1 (fr) | 2023-04-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN111386465B (zh) | 诊断测试系统和方法 | |
WO2023056985A1 (fr) | Procédé de régulation de la température d'incubation pour analyseur d'immunodosage par fluorescence, et support et système de détection par pcr | |
JP6850340B2 (ja) | 抗菌薬感受性試験を実施すること、ならびに関係するシステムおよび方法 | |
EP2809767B1 (fr) | Appareil d'amplification et de détection d'acide nucléique | |
US20190366346A1 (en) | Systems and methods for molecular diagnostics | |
TWI392863B (zh) | 反應容器、反應容器液體導入裝置、液體導入反應測定裝置及液體導入裝置 | |
KR102206856B1 (ko) | 중합효소 연쇄반응 시스템 | |
US20080057544A1 (en) | System for rapid nucleic acid amplification and detection | |
JP7497371B2 (ja) | 重合酵素連鎖反応システム | |
CN102618439A (zh) | 基于封闭反应器的dna片段扩增和定量检测系统 | |
US10393659B2 (en) | Instrument and method for detecting analytes | |
CN108421577B (zh) | 用于执行热熔分析和扩增的装置、系统和方法 | |
JP6945651B2 (ja) | 生体試料の急速加熱のための方法および装置 | |
JP2010506583A (ja) | 核酸の増幅及び検出装置 | |
JP2010207237A (ja) | ポリヌクレオチドの検出及び定量装置 | |
JP5444632B2 (ja) | 核酸増幅方法およびそれに用いる容器 | |
JP2022093423A (ja) | サンプルを分析し、光信号検出器の性能を監視するシステム及び方法 | |
WO2004046719A1 (fr) | Dispositif centrifuge et procede permettant d'effectuer des analyses par liaison | |
JPWO2020132279A5 (fr) | ||
CN113755316A (zh) | 可切换的温育模块、pcr扩增检测仪 | |
JP2014071056A (ja) | 光学的測定装置及び光学的測定用マイクロチップ | |
WO2013190062A1 (fr) | Dispositif permettant des hybridations d'acide nucléique et des immuno-essais | |
CN215975838U (zh) | 用于扩增反应的加热组件、pcr扩增检测仪 | |
CN112708546B (zh) | 一种全集成核酸即时检测装置及其应用 | |
US20180208970A1 (en) | Direct quantitative pcr device and method of use thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination |