CN113925915A - Borneol gel for treating gout - Google Patents

Borneol gel for treating gout Download PDF

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Publication number
CN113925915A
CN113925915A CN202111110222.5A CN202111110222A CN113925915A CN 113925915 A CN113925915 A CN 113925915A CN 202111110222 A CN202111110222 A CN 202111110222A CN 113925915 A CN113925915 A CN 113925915A
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Prior art keywords
gel
borneol
radix
gout
rhizoma
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蔡庆财
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Kailekang Pharmaceutical Technology Co ltd
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Kailekang Pharmaceutical Technology Co ltd
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Priority to CN202111110222.5A priority Critical patent/CN113925915A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/55Glands not provided for in groups A61K35/22 - A61K35/545, e.g. thyroids, parathyroids or pineal glands
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/59Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/68Plantaginaceae (Plantain Family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/884Alismataceae (Water-plantain family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884Arisaema, e.g. Jack in the pulpit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a borneol gout gel, which is prepared from the following raw material medicines and auxiliary materials, wherein the raw material medicines are in the following weight ratio: 80-140g of giant knotweed rhizome, 80-100 g of plantain herb, 30-40g of honeycomb, 3-5g of natural borneol, 10-20g of raw arisaema tuber, 60-90g of mint, 20-100g of pseudo-ginseng, 20-100g of golden nail, 10-50g of corydalis tuber, 30-40g of musk, 3-150g of rhizoma alismatis, 4-210g of medicinal cyathula root, 5-130g of fourstamen stephania root, 10-20g of hawthorn, 5-10g of seaweed, 40-50g of geranium and 20-40g of radix gleditsiae. Compared with the current chemotherapeutic medicine for treatment, the prepared gel is an external medicine, adverse reaction and toxic and side effect are obviously reduced, the gel has good permeability, can directly reach the affected part, has anti-inflammatory and analgesic effects, has obvious treatment effect, obviously improves the medication compliance of patients with gouty arthritis, and improves the life quality of the patients; the gel contains a plurality of medicinal components, effectively solves the source of gouty arthritis, and has the effect of treating both principal and secondary aspects of diseases on the treatment effect of the gouty arthritis.

Description

Borneol gel for treating gout
Technical Field
The invention relates to the technical field of medicines, and particularly relates to borneol gel for treating gout.
Background
At present, colchicine is used as a treatment medicament for gouty arthritis, and Baotan or indomethacin can be selected. The continuous rise of serum uric acid can also be treated by using the carbendazim, and the medicine plays a role in treating the reabsorption of urate by inhibiting renal tubules and is one of effective treatment medicines. If kidney disease is present, allopurines are often the treatment of choice. In the acute stage, steroid injection into joints, joint immobilization and cold compress of local parts can obviously relieve symptoms. However, although the western medicines can rapidly relieve symptoms, the recurrence rate is high, and the disease can rebound after the medicine is stopped, the western medicines must be taken for a long time without interruption, so that the western medicines bring a large economic burden to patients, and the western medicines have large toxic and side effects on the kidney after long-term administration.
Disclosure of Invention
Compared with the current chemotherapeutic medicine for treatment, the borneol gout gel is an external medicine, adverse reaction and toxic and side effects are obviously reduced, the gel has good permeability, can directly reach the affected part, has anti-inflammatory and analgesic effects, has obvious treatment effect, obviously improves the medication compliance of patients with gouty arthritis, and improves the life quality of the patients; the gel contains a plurality of medicinal components, effectively solves the source of gouty arthritis, and has the effect of treating both principal and secondary aspects of diseases on the treatment effect of the gouty arthritis.
In order to solve the technical problems, the invention discloses borneol gout gel which is prepared from the following raw material medicines and auxiliary materials, wherein the raw material medicines are in the following weight ratio: 80-140g of giant knotweed rhizome, 80-100 g of plantain herb, 30-40g of honeycomb, 3-5g of natural borneol, 10-20g of raw arisaema tuber, 60-90g of mint, 20-100g of pseudo-ginseng, 20-100g of golden nail, 10-50g of corydalis tuber, 30-40g of musk, 3-150g of rhizoma alismatis, 4-210g of medicinal cyathula root, 5-130g of fourstamen stephania root, 10-20g of hawthorn, 5-10g of seaweed, 40-50g of geranium and 20-40g of radix gleditsiae.
According to an embodiment of the invention, the auxiliary materials are as follows: 90-120 g of borneol liquid and 500g of medicinal yellow wine.
According to an embodiment of the invention, the ratio of the borneol liquid to the medicinal yellow wine is 1: 5.
According to an embodiment of the invention, the processing method of the borneol gout gel comprises the following specific steps: 1) weighing the following raw materials by weight: rhizoma Polygoni Cuspidati, herba plantaginis, nidus Vespae, Borneolum Syntheticum, rhizoma arisaematis, herba Menthae, Notoginseng radix, squama Manis, rhizoma corydalis, Moschus, Alismatis rhizoma, radix Cyathulae, radix Stephaniae Tetrandrae, fructus crataegi, Sargassum, herba Erodii seu Geranii, and radix Zanthoxyli Spinifolii, pulverizing with a Chinese medicinal pulverizer, and sieving with 100 mesh sieve;
2) uniformly mixing the raw material powder prepared in the step 1 with the auxiliary material medicine, putting the mixture into a pot, standing for 3 to 4 hours, and slightly boiling for 5 to 12 hours;
3) slightly boiling for 5-12 hours, cooling, and cooling in a tank;
4) uniformly stirring the liquid in the tank, and standing for 1-2 months to prepare a stock solution;
5) taking out a proper amount of stock solution and filling the stock solution into a gel bottle.
Compared with the prior art, the application can obtain the following technical effects:
1) compared with the current chemotherapeutic drugs for treatment, the gel is an external drug, the adverse reaction and the toxic and side effect are obviously reduced, the gel has good permeability, can directly reach the affected part, has anti-inflammatory and analgesic effects and obvious treatment effect, the medication compliance of patients with gouty arthritis is obviously improved, and the life quality of the patients is improved; the gel contains a plurality of medicinal components, effectively solves the source of gouty arthritis, and has the effect of treating both principal and secondary aspects of diseases on the treatment effect of the gouty arthritis.
2) The Longnao liquid has the efficacies of dispelling wind and removing dampness, dispersing dampness and relieving pain and the like, is compatible and combined with various other traditional Chinese medicines and is complementary to the other traditional Chinese medicines, achieves the purposes of resisting inflammation and easing pain, and has definite curative effect on gouty arthritis.
Of course, it is not necessary for any one product to achieve all of the above technical results simultaneously in the practice of the present invention.
Detailed Description
The following embodiments will be described in detail with reference to the accompanying examples, so that how to implement the technical means for solving the technical problems and achieving the technical effects of the present application can be fully understood and implemented.
The borneol gel for treating gout is prepared from the following raw material medicines and auxiliary materials, wherein the raw material medicines are in the following weight ratio: 80-140g of giant knotweed rhizome, 80-100 g of plantain herb, 30-40g of honeycomb, 3-5g of natural borneol, 10-20g of raw arisaema tuber, 60-90g of mint, 20-100g of pseudo-ginseng, 20-100g of golden nail, 10-50g of corydalis tuber, 30-40g of musk, 3-150g of rhizoma alismatis, 4-210g of medicinal cyathula root, 5-130g of fourstamen stephania root, 10-20g of hawthorn, 5-10g of seaweed, 40-50g of geranium and 20-40g of radix gleditsiae; the auxiliary materials are prepared from the following components in parts by weight: 90-120 g of borneol liquid and 500g of medicinal yellow wine; the ratio of the borneol liquid to the medicinal yellow wine is 1: 5.
In the embodiment of the invention, the borneol liquid has the effects of dispelling wind, promoting diuresis, dissipating dampness, relieving pain and the like, is compatible and combined with various other traditional Chinese medicines and is complementary to the traditional Chinese medicines, so that the purposes of resisting inflammation and easing pain are achieved, and the borneol liquid has a definite curative effect on gouty arthritis. Compared with the current chemotherapeutic drugs for treatment, the gel is an external drug, the adverse reaction and the toxic and side effect are obviously reduced, the gel has good permeability, can directly reach the affected part, has anti-inflammatory and analgesic effects and obvious treatment effect, the medication compliance of patients with gouty arthritis is obviously improved, and the life quality of the patients is improved; the gel contains a plurality of medicinal components, effectively solves the source of gouty arthritis, and has the effect of treating both principal and secondary aspects of diseases on the treatment effect of the gouty arthritis.
A processing method of borneol gout gel comprises the following specific steps: 1) weighing the following raw materials by weight: rhizoma Polygoni Cuspidati, herba plantaginis, nidus Vespae, Borneolum Syntheticum, rhizoma arisaematis, Camphora, Notoginseng radix, squama Manis, rhizoma corydalis, Moschus, Alismatis rhizoma, radix Cyathulae, radix Stephaniae Tetrandrae, fructus crataegi, Sargassum, herba Erodii seu Geranii, and radix Zanthoxyli Spinifolii, pulverizing with a Chinese medicinal pulverizer, and sieving with 100 mesh sieve; 2) uniformly mixing the raw material powder prepared in the step 1 with the auxiliary material medicine, putting the mixture into a pot, standing for 3 to 4 hours, and slightly boiling for 5 to 12 hours; 3) slightly boiling for 5-12 hours, cooling, and cooling in a tank; 4) uniformly stirring the liquid in the tank, and standing for 1-2 months to prepare a stock solution; 5) taking out a proper amount of stock solution and filling the stock solution into a gel bottle.
The foregoing description shows and describes several preferred embodiments of the present application, but as before, it is to be understood that the application is not limited to the forms disclosed herein, but is not to be construed as excluding other embodiments and is capable of use in various other combinations, modifications, and environments and is capable of changes within the scope of the application as contemplated by the above teachings or as would normally occur to one skilled in the relevant art. And that modifications and variations may be effected by those skilled in the art without departing from the spirit and scope of the application, which is to be protected by the claims appended hereto.

Claims (4)

1. The borneol gel for treating gout is characterized by being prepared from the following raw material medicines and auxiliary materials, wherein the raw material medicines are in the following weight ratio: 80-140g of giant knotweed rhizome, 80-100 g of plantain herb, 30-40g of honeycomb, 3-5g of natural borneol, 10-20g of raw arisaema tuber, 60-90g of mint, 20-100g of pseudo-ginseng, 20-100g of golden nail, 10-50g of corydalis tuber, 30-40g of musk, 3-150g of rhizoma alismatis, 4-210g of medicinal cyathula root, 5-130g of fourstamen stephania root, 10-20g of hawthorn, 5-10g of seaweed, 40-50g of geranium and 20-40g of radix gleditsiae.
2. The borneol gout gel of claim 1, wherein the auxiliary materials are prepared from the following components in parts by weight: 90-120 g of borneol liquid and 500g of medicinal yellow wine.
3. The borneol gout gel of claim 2, wherein the ratio of the borneol liquid to the medicinal yellow wine is 1: 5.
4. The processing method of the borneol gout gel according to any one of claims 1 to 2, characterized by comprising the following specific steps:
1) weighing the following raw materials by weight: rhizoma Polygoni Cuspidati, herba plantaginis, nidus Vespae, Borneolum Syntheticum, rhizoma arisaematis, herba Menthae, Notoginseng radix, squama Manis, rhizoma corydalis, Moschus, Alismatis rhizoma, radix Cyathulae, radix Stephaniae Tetrandrae, fructus crataegi, Sargassum, herba Erodii seu Geranii, and radix Zanthoxyli Spinifolii, pulverizing with a Chinese medicinal pulverizer, and sieving with 100 mesh sieve;
2) uniformly mixing the raw material powder prepared in the step 1 with the auxiliary material medicine, putting the mixture into a pot, standing for 3 to 4 hours, and slightly boiling for 5 to 12 hours;
3) slightly boiling for 5-12 hours, cooling, and cooling in a tank;
4) uniformly stirring the liquid in the tank, and standing for 1-2 months to prepare a stock solution;
5) taking out a proper amount of stock solution and filling the stock solution into a gel bottle.
CN202111110222.5A 2021-09-23 2021-09-23 Borneol gel for treating gout Pending CN113925915A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1709454A (en) * 2005-07-04 2005-12-21 北京润德康医药科技有限公司 Chinese medicine formulation for treating arthrolithiasis, and its preparing method
CN103877438A (en) * 2014-03-13 2014-06-25 广西中医药大学 Traditional Chinese medicine preparation for treating gout and production method thereof
CN104825554A (en) * 2015-04-22 2015-08-12 广州暨南生物医药研究开发基地有限公司 Gouty arthritis treatment spraying agent
CN105412499A (en) * 2015-12-02 2016-03-23 天津太平洋制药有限公司 Medicine for treating gout
CN109260338A (en) * 2018-10-26 2019-01-25 特医科技(合肥)有限公司 A kind of gout spray
CN109806313A (en) * 2019-04-03 2019-05-28 陕西苗三爷昕时业医药管理有限公司 A kind of externally applied drug for treating gout

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1709454A (en) * 2005-07-04 2005-12-21 北京润德康医药科技有限公司 Chinese medicine formulation for treating arthrolithiasis, and its preparing method
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