CN113727757A - 使用结合met的抗-met抗体和双特异性抗原结合分子治疗眼癌的方法 - Google Patents

使用结合met的抗-met抗体和双特异性抗原结合分子治疗眼癌的方法 Download PDF

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CN113727757A
CN113727757A CN202080029895.5A CN202080029895A CN113727757A CN 113727757 A CN113727757 A CN 113727757A CN 202080029895 A CN202080029895 A CN 202080029895A CN 113727757 A CN113727757 A CN 113727757A
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met
amino acid
antibody
acid sequence
seq
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Chinese (zh)
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G·施瓦兹
O·苏里加
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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CN202080029895.5A 2019-02-21 2020-02-20 使用结合met的抗-met抗体和双特异性抗原结合分子治疗眼癌的方法 Pending CN113727757A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962808839P 2019-02-21 2019-02-21
US62/808,839 2019-02-21
US201962823788P 2019-03-26 2019-03-26
US62/823,788 2019-03-26
PCT/US2020/019126 WO2020172475A1 (en) 2019-02-21 2020-02-20 Methods of treating ocular cancer using anti-met antibodies and bispecific antigen binding molecules that bind met

Publications (1)

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CN113727757A true CN113727757A (zh) 2021-11-30

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CN202080029895.5A Pending CN113727757A (zh) 2019-02-21 2020-02-20 使用结合met的抗-met抗体和双特异性抗原结合分子治疗眼癌的方法

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US (1) US20220040319A1 (https=)
EP (1) EP3927435A1 (https=)
JP (1) JP2022523360A (https=)
KR (1) KR20210130755A (https=)
CN (1) CN113727757A (https=)
AU (1) AU2020224136C1 (https=)
CA (1) CA3128519A1 (https=)
IL (1) IL285308A (https=)
MX (1) MX2021010114A (https=)
SG (1) SG11202108525VA (https=)
WO (1) WO2020172475A1 (https=)

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US11896682B2 (en) 2019-09-16 2024-02-13 Regeneron Pharmaceuticals, Inc. Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof
WO2022204332A1 (en) * 2021-03-24 2022-09-29 Combangio, Inc. Compositions comprising c-met agonist antibodies and methods for use in ocular treatment
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WO2024002256A1 (en) * 2022-06-29 2024-01-04 Doma Biopharmaceutical (Suzhou) Co., Ltd. Anti-egfr/met antibodies and uses thereof

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US20180134794A1 (en) * 2016-11-16 2018-05-17 Regeneron Pharmaceuticals, Inc. Anti-met antibodies, bispecific antigen binding molecules that bind met, and methods of use thereof

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