JP2022523360A - Ｍｅｔに結合する抗ｍｅｔ抗体および二特異性抗原結合分子を使用した眼癌の治療方法 - Google Patents

Ｍｅｔに結合する抗ｍｅｔ抗体および二特異性抗原結合分子を使用した眼癌の治療方法 Download PDF

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JP2022523360A
JP2022523360A JP2021549279A JP2021549279A JP2022523360A JP 2022523360 A JP2022523360 A JP 2022523360A JP 2021549279 A JP2021549279 A JP 2021549279A JP 2021549279 A JP2021549279 A JP 2021549279A JP 2022523360 A JP2022523360 A JP 2022523360A
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met
amino acid
binding
antibody
acid sequence
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JP2022523360A5 (https=
JPWO2020172475A5 (https=
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ゲイリー シュワルツ，
オリバー スリガ，
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
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JP2021549279A 2019-02-21 2020-02-20 Ｍｅｔに結合する抗ｍｅｔ抗体および二特異性抗原結合分子を使用した眼癌の治療方法 Pending JP2022523360A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962808839P 2019-02-21 2019-02-21
US62/808,839 2019-02-21
US201962823788P 2019-03-26 2019-03-26
US62/823,788 2019-03-26
PCT/US2020/019126 WO2020172475A1 (en) 2019-02-21 2020-02-20 Methods of treating ocular cancer using anti-met antibodies and bispecific antigen binding molecules that bind met

Publications (3)

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JP2022523360A true JP2022523360A (ja) 2022-04-22
JP2022523360A5 JP2022523360A5 (https=) 2022-12-14
JPWO2020172475A5 JPWO2020172475A5 (https=) 2022-12-14

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JP2021549279A Pending JP2022523360A (ja) 2019-02-21 2020-02-20 Ｍｅｔに結合する抗ｍｅｔ抗体および二特異性抗原結合分子を使用した眼癌の治療方法

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US (1) US20220040319A1 (https=)
EP (1) EP3927435A1 (https=)
JP (1) JP2022523360A (https=)
KR (1) KR20210130755A (https=)
CN (1) CN113727757A (https=)
AU (1) AU2020224136C1 (https=)
CA (1) CA3128519A1 (https=)
IL (1) IL285308A (https=)
MX (1) MX2021010114A (https=)
SG (1) SG11202108525VA (https=)
WO (1) WO2020172475A1 (https=)

Cited By (1)

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US12545735B2 (en) 2016-11-16 2026-02-10 Regeneron Pharmaceuticals, Inc. Anti-met antibodies, bispecific antigen binding molecules that bind met, and methods of use thereof

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Publication number Priority date Publication date Assignee Title
US11896682B2 (en) 2019-09-16 2024-02-13 Regeneron Pharmaceuticals, Inc. Radiolabeled MET binding proteins for immuno-PET imaging and methods of use thereof
WO2022204332A1 (en) * 2021-03-24 2022-09-29 Combangio, Inc. Compositions comprising c-met agonist antibodies and methods for use in ocular treatment
WO2023055207A1 (ko) 2021-10-01 2023-04-06 주식회사 엘지화학 열가소성 수지조성물
WO2024002256A1 (en) * 2022-06-29 2024-01-04 Doma Biopharmaceutical (Suzhou) Co., Ltd. Anti-egfr/met antibodies and uses thereof

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US20180134794A1 (en) * 2016-11-16 2018-05-17 Regeneron Pharmaceuticals, Inc. Anti-met antibodies, bispecific antigen binding molecules that bind met, and methods of use thereof
WO2018098035A1 (en) * 2016-11-23 2018-05-31 Eli Lilly And Company Met antibody drug conjugates

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