CN113694141A - 一种治疗烫伤的中药材提取物及其制备方法 - Google Patents

一种治疗烫伤的中药材提取物及其制备方法 Download PDF

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CN113694141A
CN113694141A CN202111200187.6A CN202111200187A CN113694141A CN 113694141 A CN113694141 A CN 113694141A CN 202111200187 A CN202111200187 A CN 202111200187A CN 113694141 A CN113694141 A CN 113694141A
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徐杨森
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Dongtai Hanfangyuan Biotechnology Co ltd
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Abstract

本发明公开了一种治疗烫伤的中药材提取物，包括以下重量组份的原料：延胡索22‑28份、地锦草13‑19份、地黄12‑18份、虎杖5‑15份、柴胡8‑10份、三七8‑10份、儿茶18‑28份、绞股蓝6‑9份、黄连7‑9份、大黄8‑12份、紫草12‑18份、合欢皮12‑18份、四方麻8‑10份、黄柏4‑9份、大蓟22‑28份、蛇蜕5‑7份、红景天8‑10份、青黛20‑25份、白芨7‑9份、地榆18‑26份、乳香12‑18份、没药12‑18份、蜂蜡35‑55份。本发明的优点：副作用较小，对人体的伤害较小且可以较快的速度治疗患者的烫伤处，减轻患者痛苦。

Description

一种治疗烫伤的中药材提取物及其制备方法
技术领域
本发明涉及中药提取技术领域，具体是指一种治疗烫伤的中药材提取物及其制备方法。
背景技术
烫伤是由高温液体、高温固体或高温蒸气等所致的损伤，属于常见病。临床上一般分为三类，即轻度烧伤、中度烧伤、重度烧伤等，烫伤多见于儿童。烫伤的主要临床表现为皮肤红肿、水疱，以及疼痛，及时治疗一般预后良好。若治疗不及时，容易造成瘢痕增生、感染，严重者可导致休克。
现有的烫伤治疗基本都是利用西药药膏以及内服西药进行治疗，其治疗效果较快，但副作用较大，对人体的危害是不可逆的；现在也有一些中药治疗烫伤的，但普通的治疗烫伤的中药治疗烫伤引起的红肿、水泡、肿胀、糜烂疗效较差，并且治愈时间较长，患者需要忍受的痛苦较大。
发明内容
本发明为了解决上述的各种问题，提供了一种治疗烫伤的中药材提取物及其制备方法，其副作用较小，对人体的伤害较小且可以较快的速度治疗患者的烫伤处，减轻患者痛苦。
为解决上述技术问题，本发明提供的技术方案为：一种治疗烫伤的中药材提取物，包括以下重量组份的原料：延胡索22-28份、地锦草13-19份、地黄12-18份、虎杖5-15份、柴胡8-10份、三七8-10份、儿茶18-28份、绞股蓝6-9份、黄连7-9份、大黄8-12份、紫草12-18份、合欢皮12-18份、四方麻8-10份、黄柏4-9份、大蓟22-28份、蛇蜕5-7份、红景天8-10份、青黛20-25份、白芨7-9份、地榆18-26份、乳香12-18份、没药12-18份、蜂蜡35-55份。
优选的，取用以下重量组份的原料：延胡索25份、地锦草16份、地黄15份、虎杖10份、柴胡9份、三七9份、儿茶23份、绞股蓝7份、黄连8份、大黄10份、紫草15份、合欢皮15份、四方麻9份、黄柏7份、大蓟25份、蛇蜕6份、红景天9份、青黛23份、白芨8份、地榆22份、乳香15份、没药15份、蜂蜡45份。
本发明还包括一种治疗烫伤的中药材提取物的制备方法，包括以下制备步骤：
步骤一：选材：分别选取并称重所需重量的延胡索、地锦草、地黄、虎杖、柴胡、三七、儿茶、绞股蓝、黄连、大黄、紫草、合欢皮、四方麻、黄柏、大蓟、蛇蜕、红景天、青黛、白芨、地榆、乳香、没药、蜂蜡；
步骤二：预处理：将步骤一中称重后的原料分别进行清洗、烘干和粉碎；
步骤三：浸泡：将粉碎后的各原料置于充有高浓度乙醇的容器内，分别进行浸泡，浸泡时间至少为10h；
步骤四：萃取：将浸泡后的混合液投入搅拌加热反应釜内进行加热并搅拌，从而将乙醇挥发出来，并使原料内的汁液能萃取而出；
步骤五：离心：将萃取出的汁液过滤后，倒入至离心设备中进行离心操作，去除大颗粒杂质；
步骤六：将离心后的液体投入至浓缩器内进行浓缩，至无水分，得各原料的提取浓缩物；
步骤七：将各原料提取浓缩物一同置于搅拌罐内进行搅拌混合，得混合提取物。
优选的，所述步骤三中，乙醇浓度为85％-95％。
优选的，所述步骤四中，搅拌加热反应釜的工作条件为：温度为60℃，时间为2h，搅拌转速为200rpm。
优选的，所述步骤五中，所述离心设备的转速为3500rpm，离心时间为10min。
优选的，所述步骤六中，浓缩器的型号为KH05-KH-NSQ，浓缩压强为40-50kPa，温度为35-40℃。
本发明与现有技术相比的优点在于：各原料的功效：
延胡索：以块茎入药，有活血散淤、利气止痛的功能，主治心腹腰膝疼痛、跌打损伤、淤血作痛、月经不调等症，是一味传统的止痛药，用以初步缓解患者痛苦。
地锦草：能够清热解毒；利湿退黄；活血止血。
地黄：具有滋阴补肾、养血补血、凉血的功效。凡阴虚血虚肾虚者食之，颇有益处。此外，地黄有强心利尿、解热消炎、促进血液凝固和降低血糖的作用。
虎杖：根状茎供药用，有活血、散瘀、通经、镇咳等功效。
儿茶：收湿生肌敛疮。用于溃疡不敛，湿疹，口疮，跌扑伤痛，外伤出血。
绞股蓝：益气健脾，化痰止咳，清热解毒。
紫草：凉血，活血，清热，解毒。治温热斑疹，湿热黄疸，紫癜，吐、衄、尿血，淋浊，热结便秘，烧伤，湿疹，丹毒，痈疡。
合欢皮：性味甘、平。有解郁、和血、宁心、消痈肿之功。
四方麻：清热，解毒，消肿，止痛，生肌长肉。治红白痢，喉痛，目赤，黄肿，淋病，下疳，刀伤，痈疽，瘰疬，皮肤溃疡，湿疹，烫伤。
大蓟：功能治吐血，衄血，尿血，血淋，血崩，带下，肠风，肠痈，痈疡肿毒，疔疮。
青黛：主治热毒发斑、吐血等症；外敷治疮疡，痄腮。
本发明在使用时，其中的中药提取物在治疗烫伤方面具有非常好的疗效，对烫伤引起的红肿、水泡、肿胀、糜烂的治疗效果非常好，并且不留疤痕，且治疗时间较短，对人体副作用较小，不会使患者承受较大的痛苦。
具体实施方式
下面结合实施例对本发明做进一步的详细说明。
实施例1
一种治疗烫伤的中药材提取物，取用以下重量组份的原料：延胡索22份、地锦草13份、地黄12份、虎杖5份、柴胡8份、三七8份、儿茶18份、绞股蓝6份、黄连7份、大黄8份、紫草12份、合欢皮12份、四方麻8份、黄柏4份、大蓟22份、蛇蜕5份、红景天8份、青黛20份、白芨7份、地榆18份、乳香12份、没药12份、蜂蜡35份。
实施例2
一种治疗烫伤的中药材提取物，包括以下重量组份的原料：延胡索28份、地锦草19份、地黄18份、虎杖15份、柴胡10份、三七10份、儿茶28份、绞股蓝9份、黄连9份、大黄12份、紫草18份、合欢皮18份、四方麻10份、黄柏9份、大蓟28份、蛇蜕7份、红景天10份、青黛25份、白芨9份、地榆26份、乳香18份、没药18份、蜂蜡55份。
实施例3
一种治疗烫伤的中药材提取物，取用以下重量组份的原料：延胡索25份、地锦草16份、地黄15份、虎杖10份、柴胡9份、三七9份、儿茶23份、绞股蓝7份、黄连8份、大黄10份、紫草15份、合欢皮15份、四方麻9份、黄柏7份、大蓟25份、蛇蜕6份、红景天9份、青黛23份、白芨8份、地榆22份、乳香15份、没药15份、蜂蜡45份。
本发明还包括一种治疗烫伤的中药材提取物的制备方法，包括以下制备步骤：
步骤一：选材：分别选取并称重所需重量的延胡索、地锦草、地黄、虎杖、柴胡、三七、儿茶、绞股蓝、黄连、大黄、紫草、合欢皮、四方麻、黄柏、大蓟、蛇蜕、红景天、青黛、白芨、地榆、乳香、没药、蜂蜡；
步骤二：预处理：将步骤一中称重后的原料分别进行清洗、烘干和粉碎；
步骤三：浸泡：将粉碎后的各原料置于充有85％-95％乙醇的容器内，分别进行浸泡，浸泡时间至少为10h；
步骤四：萃取：将浸泡后的混合液投入搅拌加热反应釜内进行加热并搅拌，从而将乙醇挥发出来，并使原料内的汁液能萃取而出；
步骤五：离心：将萃取出的汁液过滤后，倒入至离心设备中进行离心操作，转速为3500rpm，离心时间为10min，去除大颗粒杂质；
步骤六：将离心后的液体投入至浓缩器内进行浓缩，至无水分，得各原料的提取浓缩物；
步骤七：将各原料提取浓缩物一同置于搅拌罐内进行搅拌混合，得混合提取物。
所述步骤四中，搅拌加热反应釜的工作条件为：温度为60℃，时间为2h，搅拌转速为200rpm。
所述步骤六中，浓缩器的型号为KH05-KH-NSQ，浓缩压强为40-50kPa，温度为35-40℃。
以上对本发明及其实施方式进行了描述，这种描述没有限制性，实施例中所示的也只是本发明的几个实施方式，实际的实施方式并不局限于此。总而言之如果本领域的普通技术人员受其启示，在不脱离本发明创造宗旨的情况下，不经创造性的设计出与该技术方案相似的实施方式及实施例，均应属于本发明的保护范围。

Claims (7)

1.一种治疗烫伤的中药材提取物，其特征在于:包括以下重量组份的原料：延胡索22-28份、地锦草13-19份、地黄12-18份、虎杖5-15份、柴胡8-10份、三七8-10份、儿茶18-28份、绞股蓝6-9份、黄连7-9份、大黄8-12份、紫草12-18份、合欢皮12-18份、四方麻8-10份、黄柏4-9份、大蓟22-28份、蛇蜕5-7份、红景天8-10份、青黛20-25份、白芨7-9份、地榆18-26份、乳香12-18份、没药12-18份、蜂蜡35-55份。
2.根据权利要求1所述的一种治疗烫伤的中药材提取物，其特征在于：取用以下重量组份的原料：延胡索25份、地锦草16份、地黄15份、虎杖10份、柴胡9份、三七9份、儿茶23份、绞股蓝7份、黄连8份、大黄10份、紫草15份、合欢皮15份、四方麻9份、黄柏7份、大蓟25份、蛇蜕6份、红景天9份、青黛23份、白芨8份、地榆22份、乳香15份、没药15份、蜂蜡45份。
3.一种治疗烫伤的中药材提取物的制备方法，其特征在于：包括以下制备步骤：
步骤一：选材：分别选取并称重所需重量的延胡索、地锦草、地黄、虎杖、柴胡、三七、儿茶、绞股蓝、黄连、大黄、紫草、合欢皮、四方麻、黄柏、大蓟、蛇蜕、红景天、青黛、白芨、地榆、乳香、没药、蜂蜡；
步骤二：预处理：将步骤一中称重后的原料分别进行清洗、烘干和粉碎；
步骤三：浸泡：将粉碎后的各原料置于充有高浓度乙醇的容器内，分别进行浸泡，浸泡时间至少为10h；
步骤四：萃取：将浸泡后的混合液投入搅拌加热反应釜内进行加热并搅拌，从而将乙醇挥发出来，并使原料内的汁液能萃取而出；
步骤五：离心：将萃取出的汁液过滤后，倒入至离心设备中进行离心操作，去除大颗粒杂质；
步骤六：将离心后的液体投入至浓缩器内进行浓缩，至无水分，得各原料的提取浓缩物；
步骤七：将各原料提取浓缩物一同置于搅拌罐内进行搅拌混合，得混合提取物。
4.根据权利要求3所述的一种治疗烫伤的中药材提取物的制备方法，其特征在于：所述步骤三中，乙醇浓度为85％-95％。
5.根据权利要求3所述的一种治疗烫伤的中药材提取物的制备方法，其特征在于：所述步骤四中，搅拌加热反应釜的工作条件为：温度为60℃，时间为2h，搅拌转速为200rpm。
6.根据权利要求3所述的一种治疗烫伤的中药材提取物的制备方法，其特征在于：所述步骤五中，所述离心设备的转速为3500rpm，离心时间为10min。
7.根据权利要求3所述的一种治疗烫伤的中药材提取物的制备方法，其特征在于：所述步骤六中，浓缩器的型号为KH05-KH-NSQ，浓缩压强为40-50kPa，温度为35-40℃。
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CN105943778A (zh) * 2016-07-24 2016-09-21 王中杰 一种治疗烧烫伤的中药组合物及其制备方法
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