CN113694003A - 一种海盐杀菌抑菌漱口水及其制备方法 - Google Patents
一种海盐杀菌抑菌漱口水及其制备方法 Download PDFInfo
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Abstract
本发明提供了一种海盐杀菌抑菌漱口水及其制备方法，包括按质量百分比计的如下组分：海盐5～8％，甜味剂2～8％，碳酸氢钠1～3％，甘草酸二钾0.1～1.5％，抑菌剂0.1～1.5％，食用香精0.2～1.8％，功效成分0.25～1.7％，维生素C0.05～0.28％，食用色素0.01～0.05％，其余为水。本发明所述的海盐杀菌抑菌漱口水中含有金银花提取物、蜂胶提取物，有助于口腔黏膜的修复，加速口腔溃疡的愈合，不辣口，刺激性小，可长期使用；能够有效抑制具核梭杆菌和伴放线杆菌口腔致病菌的生长，并有效杀灭口腔致病菌，能够有效预防由细菌引起的牙周疾病。
Description
技术领域
本发明属于口腔护理用品技术领域，尤其是涉及一种海盐杀菌抑菌漱口水及其制备方法。
背景技术
口腔疾病是由口腔中的各种致病菌引起的常见多发病，直接影响人们的身体健康，长期以来，人们主要通过使用各种牙膏和漱口水来清洁口腔，防止口腔疾病的发生。近年来，在牙膏中加入各种中草药成分制成的各种药物产品相继出现，但由于其携带不便，使用不便，且使用时在口腔中停留时间很短，抗菌效果不显著，并且现有的中草药提取成分并不稳定，容易变质，导致产品添加了更多的防腐剂。
发明内容
有鉴于此，本发明旨在提出一种性质温和、刺激性小、安全无毒、易溶于水、消炎抗菌效用好、适用范围广的海盐杀菌抑菌漱口水，同时提供了所述漱口水的制备方法，以解决上述问题。
为达到上述目的，本发明的技术方案是这样实现的：
一种海盐杀菌抑菌漱口水，包括按质量百分比计的如下组分：海盐5～8％，甜味剂2～8％，碳酸氢钠1～3％，甘草酸二钾0.1～1.5％，抑菌剂0.1～1.5％，食用香精0.2～1.8％，功效成分0.25～1.7％，维生素C0.05～0.28％，食用色素0.01～0.05％，其余为水。
根据食用香精的味道不同，可得到不同口味的漱口水(如玫瑰口味、蜜桃口味、绿茶口味、咖啡口味)；根据食用色素的颜色不同，可得到不同颜色的漱口水，具体可配合味道的不同呈现不同的颜色。
进一步的，所述甜味剂为山梨糖醇和木糖醇。
进一步的，按质量百分比计所述山梨糖醇占总量的1～4％，所述木糖醇占总量的1～4％。
进一步的，所述抑菌剂为度米芬。
进一步的，所述功效成分为金银花提取物、蜂胶提取物。
进一步的，所述功效成分还包括茶多酚。
进一步的，按质量百分比计所述金银花提取物占总量的0.1～0.9％、蜂胶提取物占总量的0.1～0.5％、茶多酚占总量的0.05-0.3％。
进一步的，所述金银花提取物通过将金银花原料加水煎煮后浓缩，再由乙醇进行醇沉后，得到的醇沉上清液过滤后浓缩得到。
进一步的，所述蜂胶提取物通过将蜂胶在乙醇和石油醚中多次萃取过滤，合并萃取液减压浓缩后得到。
一种海盐杀菌抑菌漱口水的制备方法，包括如下步骤：
S1、制备金银花提取物和蜂胶提取物：
将金银花原料加水浸泡后煎煮，过筛网，将得到的煎煮液浓缩，加入乙醇，进行醇沉后，得到的醇沉上清液过滤后浓缩得到金银花提取物，备用；
将蜂胶原料清洗除杂后，将其放入萃取器中，加入乙醇和石油醚，萃取、冷却、过滤；重复多次，合并萃取液，减压浓缩后得到蜂胶提取物，备用；
S2、按照配比称取各组分：海盐5～8％，甜味剂2～8％，碳酸氢钠1～3％，甘草酸二钾0.1～1.5％，抑菌剂0.1～1.5％，食用香精0.2～1.8％，金银花提取物0.1～0.9％，蜂胶提取物0.1～0.5％、茶多酚0.05-0.3％，维生素C0.05～0.28％，食用色素0.01～0.05％，其余为水；
S3、取部分水，加入到金银花提取物和蜂胶提取物中，搅拌，得到混合液；
S4、将剩余的组分混合，加入剩余的水，搅拌混合后，再加入S3所述的混合液，继续搅拌至均匀，过滤后得到所述漱口水；
S5、将S4得到的漱口水灭菌后灌装，得到包装后的漱口水。
相对于现有技术，本发明所述的海盐杀菌抑菌漱口水及其制备方法具有以下优势：
(1)本发明所述的海盐杀菌抑菌漱口水中含有金银花提取物、蜂胶提取物，有助于口腔黏膜的修复，加速口腔溃疡的愈合，不辣口，刺激性小，可长期使用；
(2)本发明所述的海盐杀菌抑菌漱口水能够有效抑制具核梭杆菌和伴放线杆菌口腔致病菌的生长，并有效杀灭口腔致病菌，能够有效预防由细菌引起的牙周疾病；
(3)本发明所述的海盐杀菌抑菌漱口水的制备方法简单，成本低。
具体实施方式
除有定义外，以下实施例中所用的技术术语具有与本发明所属领域技术人员普遍理解的相同含义。以下实施例中所用的试验试剂，如无特殊说明，均为常规生化试剂；所述实验方法，如无特殊说明，均为常规方法。
下面结合实施例来详细说明本发明。
实施例1
按照如下质量百分比称取各组分：海盐5％，山梨糖醇4％，木糖醇1％，碳酸氢钠3％，甘草酸二钾1.5％，度米芬1.5％，食用香精(玫瑰口味)1％，金银花提取物0.9％，蜂胶提取物0.5％，维生素C0.05％，食用色素(苋菜红)0.05％，其余为水；
其中，金银花提取物通过如下方法制得：将金银花原料加水浸泡后煎煮2h，过60目筛网，将得到的煎煮液浓缩，加入乙醇搅拌均匀，进行醇沉后，得到的醇沉上清液过滤，减压浓缩得到金银花提取物；
蜂胶提取物通过如下方法制得：将蜂胶原料清洗除杂后，将其放入萃取器中，加入浓度为95％的乙醇和石油醚，在50℃萃取50min、冷却、过滤；重复上述操作3次，合并萃取液，减压浓缩后得到蜂胶提取物；
取部分水，加入到金银花提取物和蜂胶提取物中，搅拌，得到混合液；
将剩余的组分混合，加入剩余的水，搅拌混合后，再加入混合液，继续搅拌至均匀，过滤后得到漱口水，漱口水灭菌后灌装，得到包装后的漱口水。
实施例2
在实施例1的基础上，与实施例1不同的是按照如下质量百分比称取各组分：
海盐8％，山梨糖醇2％，木糖醇4％，碳酸氢钠3％，甘草酸二钾0.1％，度米芬1％，食用香精(蜜桃口味)0.5％，金银花提取物0.5％，蜂胶提取物0.5％，维生素C0.1％，食用色素(日落黄)0.02％，其余为水；
制备过程与实施例1相同。
实施例3
在实施例1的基础上，与实施例1不同的是按照如下质量百分比称取各组分：
海盐6％，山梨糖醇2％，木糖醇2％，碳酸氢钠2％，甘草酸二钾1％，度米芬0.5％，食用香精(绿茶口味)1.8％，金银花提取物0.1％，蜂胶提取物0.3％、茶多酚0.3％，维生素C0.2％，食用色素(柠檬黄、亮蓝)0.01％，其余为水；
制备过程与实施例1相同。
实施例4
在实施例1的基础上，与实施例1不同的是按照如下质量百分比称取各组分：
海盐8％，山梨糖醇1％，木糖醇4％，碳酸氢钠1％，甘草酸二钾1.5％，度米芬0.5％，食用香精(咖啡口味)1％，金银花提取物0.9％，蜂胶提取物0.5％，维生素C0.05％，食用色素(日落黄、胭脂红、亮蓝)0.02％，其余为水；
制备过程与实施例1相同。
实验测试：
所述漱口水属于口腔清洁护理液，所述漱口水产品的质量标准应符合QB/T 2945-2012口腔清洁护理液的标准。
对样品依据标准QB/T 2945-2012进行检测，样品符合标准，检测结果见表1。
表1
对样品依据标准QB/T 2738-2012(7.3)进行检测，样品具有较强抑菌作用，平均抑菌率达到99％。依据标准QB/T 2738-2012(7.2)进行检测，样品具有杀菌作用，平均杀菌率达到99％。
以上所述仅为本发明的较佳实施例而已，并不用以限制本发明，凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。
Claims (10)
1.一种海盐杀菌抑菌漱口水，其特征在于，包括按质量百分比计的如下组分：海盐5～8％，甜味剂2～8％，碳酸氢钠1～3％，甘草酸二钾0.1～1.5％，抑菌剂0.1～1.5％，食用香精0.2～1.8％，功效成分0.25～1.7％，维生素C0.05～0.28％，食用色素0.01～0.05％，其余为水。
2.根据权利要求1所述的海盐杀菌抑菌漱口水，其特征在于：所述甜味剂为山梨糖醇和木糖醇。
3.根据权利要求2所述的海盐杀菌抑菌漱口水，其特征在于：按质量百分比计所述山梨糖醇占总量的1～4％，所述木糖醇占总量的1～4％。
4.根据权利要求1所述的海盐杀菌抑菌漱口水，其特征在于：所述抑菌剂为度米芬。
5.根据权利要求1所述的海盐杀菌抑菌漱口水，其特征在于：所述功效成分为金银花提取物、蜂胶提取物。
6.根据权利要求5所述的海盐杀菌抑菌漱口水，其特征在于：所述功效成分还包括茶多酚。
7.根据权利要求6所述的海盐杀菌抑菌漱口水，其特征在于：按质量百分比计所述金银花提取物占总量的0.1～0.9％、蜂胶提取物占总量的0.1～0.5％、茶多酚占总量的0.05-0.3％。
8.根据权利要求5所述的海盐杀菌抑菌漱口水，其特征在于：所述金银花提取物通过将金银花原料加水煎煮后浓缩，再由乙醇进行醇沉后，得到的醇沉上清液过滤后浓缩得到。
9.根据权利要求5所述的海盐杀菌抑菌漱口水，其特征在于：所述蜂胶提取物通过将蜂胶在乙醇和石油醚中多次萃取过滤，合并萃取液减压浓缩后得到。
10.权利要求6所述的海盐杀菌抑菌漱口水的制备方法，其特征在于：包括如下步骤：
S1、制备金银花提取物和蜂胶提取物：
将金银花原料加水浸泡后煎煮，过筛网，将得到的煎煮液浓缩，加入乙醇，进行醇沉后，得到的醇沉上清液过滤后浓缩得到金银花提取物，备用；
将蜂胶原料清洗除杂后，将其放入萃取器中，加入乙醇和石油醚，萃取、冷却、过滤；重复多次，合并萃取液，减压浓缩后得到蜂胶提取物，备用；
S2、按照配比称取各组分：海盐5～8％，甜味剂2～8％，碳酸氢钠1～3％，甘草酸二钾0.1～1.5％，抑菌剂0.1～1.5％，食用香精0.2～1.8％，金银花提取物0.1～0.9％，蜂胶提取物0.1～0.5％、茶多酚0.05-0.3％，维生素C0.05～0.28％，食用色素0.01～0.05％，其余为水；
S3、取部分水，加入到金银花提取物和蜂胶提取物中，搅拌，得到混合液；
S4、将剩余的组分混合，加入剩余的水，搅拌混合后，再加入S3所述的混合液，继续搅拌至均匀，过滤后得到所述漱口水；
S5、将S4得到的漱口水灭菌后灌装，得到包装后的漱口水。
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