CN113633569A

CN113633569A - Anti-wrinkle firming composition and cosmetic

Info

Publication number: CN113633569A
Application number: CN202111136153.5A
Authority: CN
Inventors: 刘海勇; 潘启诚; 丛琳; 李雪竹
Original assignee: Shanghai New Cogi Cosmetic Co ltd
Current assignee: Shanghai New Cogi Cosmetic Co ltd
Priority date: 2021-09-27
Filing date: 2021-09-27
Publication date: 2021-11-12
Anticipated expiration: 2041-09-27
Also published as: CN113633569B

Abstract

The invention discloses an anti-wrinkle firming composition and cosmetics, and relates to the technical field of cosmetics, wherein the anti-wrinkle firming composition comprises the following components in percentage by weight: glycerol glucoside: 0.5-2 parts; hexapeptide-9: 1-5 parts; acetyl tetrapeptide-2: 0.5-2 parts; hydrolyzing collagen: 0.5-2 parts; the hydrolyzed collagen has a molecular weight of less than 3000 Da. The invention starts from the mechanism of wrinkle generation, specifically selects and compares various anti-wrinkle active substances from a plurality of layers such as an epidermal layer, a real epidermal connecting layer, a dermal layer and the like, further screens out a comprehensive anti-wrinkle compact composition with more comprehensive overall mechanism and more obvious effect through the optimization of components, and can achieve the effects of more quickly, continuously and effectively improving wrinkles and skin elasticity.

Description

Anti-wrinkle firming composition and cosmetic

Technical Field

The invention relates to the technical field of cosmetics, and particularly relates to an anti-wrinkle firming composition and a cosmetic.

Background

The skin of a human body inevitably generates wrinkles as it ages. The generation of skin wrinkles is a dynamic multi-level process, and is mainly related to the deterioration of various functions of the epidermis, dermis, and dermis junction (basement membrane).

Metabolism of skin epidermal cells is gradually slowed down along with the growth of the skin, the generation of epidermal lipid and natural moisturizing factors is reduced, the water storage capacity of a horny layer is reduced, an epidermal layer is thinned, and desquamation, dry lines and fine lines are easily generated on the epidermis.

Collagen I is the most prominent functional protein in the dermis layer, usually associated with collagen III, which lines the collagen fibers of the dermis, providing sufficient nutrition and strength to the dermis, and is also closely related to skin regeneration. In the structure of dermal fibers, elastin, an important protein, is the main component of dermal elastic fibers. The elastic fiber and the collagen fiber jointly form a fiber network structure of the dermis, so that the elasticity, the strength and the flexibility of the skin are endowed. With age, the synthesis of type I and type III collagen and elastin in the dermis decreases, resulting in a substantial loss of function of the collagen and elastic fibers in the dermis, which loses sufficient strength and elasticity in the dermis, resulting in deep wrinkles in the skin.

The collagen IV fixes the epidermis to the true epidermis connecting layer to form a net structure, so that the true epidermis connecting layer is stable in structure; collagen XVII is an important transmembrane protein connecting the epidermal layer and the dermal layer, and is also released as a signal for skin regeneration, and together they constitute a tensile structure of the epidermal connecting layer (basement membrane) and exert an adhesive effect. The synthesis of collagen IV and collagen XVII is reduced, the nutrition permeation between epidermis and dermis is reduced, the true epidermal junction layer (basement membrane) is flattened and even sunken and collapsed, the skin is loosened and loses toughness, and the generation of wrinkles is accelerated.

At present, most anti-wrinkle products in the market mainly focus on the supplement of collagen or elastin in the dermis, and the anti-wrinkle products have relatively single action way and are difficult to achieve quick, continuous and effective improvement effect in the aspect of wrinkle improvement.

Disclosure of Invention

The invention aims to overcome the defects of the prior art and provide an anti-wrinkle firming composition and a cosmetic.

In order to solve the technical problems, the invention provides the following technical scheme:

in a first aspect, the anti-wrinkle and anti-firming composition is composed of the following components in parts by weight:

glycerol glucoside: 0.5-2 parts;

hexapeptide-9: 1-5 parts;

acetyl tetrapeptide-2: 0.5-2 parts;

hydrolyzing collagen: 0.5-2 parts;

the hydrolyzed collagen has a molecular weight of less than 3000 Da.

Further, the composition comprises the following components in parts by weight:

glycerol glucoside: 1-2 parts;

hexapeptide-9: 2-4 parts;

acetyl tetrapeptide-2: 1-2 parts;

hydrolyzing collagen: 1-2 parts.

Further, the weight ratio of the acetyl tetrapeptide-2 to the hydrolyzed collagen is 1: 1.

In a second aspect, a cosmetic is provided, which comprises the anti-wrinkle tightening composition of the first aspect, wherein the anti-wrinkle tightening composition is present in the cosmetic in an amount of 2.5 to 10% by weight.

Furthermore, the cosmetic also comprises a cosmetic auxiliary material matrix with the weight fraction of 90-97.5%.

Further, the cosmetic auxiliary material matrix is selected from one or more of a humectant, a thickening agent, a pH regulator, an emulsifier, a preservative, an essence and water.

Further, the humectant is selected from one or more of glycerol, propylene glycol, butanediol, dipropylene glycol, isoprene glycol, 1, 3-propanediol, methyl propanediol, polyethylene glycol-32, methyl glucitol polyether-20 and glycerol polyether-26.

Preferably, the humectant is glycerin.

Further, the thickener of the present invention may be selected from conventional thickeners in the cosmetic field; the thickening agent is selected from one or more of carbomer, xanthan gum, acryloyl dimethyl ammonium taurate/VP copolymer, hydroxyethyl cellulose, sodium polyacrylate, sodium acrylate/acryloyl dimethyl sodium taurate copolymer, cetostearyl alcohol, cetyl alcohol and behenyl alcohol.

Preferably, the thickener is a mixture of carbomer and xanthan gum.

Further, the pH regulator is selected from one or more of arginine, triethanolamine and inorganic bases.

Preferably, the pH adjusting agent is arginine.

Further, the preservative is selected from one or more of methyl hydroxybenzoate, phenoxyethanol and propyl hydroxybenzoate; the essence is selected from one or more of faint scent essence, floral essence, fruity essence and composite scent essence.

Further, the emulsifier of the present invention may be selected from conventional emulsifiers in the cosmetic field; preferably, the emulsifier can be one or more of glyceryl stearate, PEG-40 sorbitan stearate, PEG-100 stearate, and polysorbate-20.

Furthermore, the cosmetics comprise dosage forms of anti-wrinkle tightening skin lotion, anti-wrinkle tightening skin cream, anti-wrinkle tightening skin gel, anti-wrinkle tightening skin spray and the like.

In a third aspect, there is provided a method for preparing the cosmetic according to the second aspect, comprising the steps of:

1. adding water, humectant and thickener into an emulsifying pot according to the weight percentage of the raw materials, stirring and heating to 80-85 ℃, preserving heat and stirring for 30 minutes, and then cooling;

2. cooling to 60 ℃, adding a pH regulator, stirring for 10 minutes until the mixture is uniform, and continuously cooling;

3. cooling to 45 deg.C, adding antiseptic and essence, adding glycerol glucoside, hexapeptide-9, acetyl tetrapeptide-2 and hydrolyzed collagen, and stirring for 10 min to obtain the final product.

Compared with the prior art, the invention has the following beneficial effects:

the invention combines the multi-layer reason of wrinkles generated by skin, and respectively starts from various aspects such as epidermis layer, real epidermis connecting layer, dermis layer and the like, and performs targeted selection and collocation of effective components, thereby not only making up the defect of single action mechanism of the existing anti-wrinkle product, but also realizing the effect of 1+1+1 > 3 by the mutual cooperation of the three, and having the effects of reducing wrinkles and improving the skin elasticity more quickly, continuously, comprehensively and effectively.

In the aspect of epidermis, the glycerol glucoside is selected as a product of glycerol and sucrose biosynthesis, so that the moisture retention of skin can be increased, the regeneration and proliferation of epidermal cells are stimulated, the activity and metabolism of the cells are enhanced, the density and the thickening of the skin are increased, and the dry lines and the roughness of the skin surface layer are rapidly improved.

In the aspect of the true epidermis connecting layer (basement membrane), hexapeptide-9 is selected, and hexapeptide-9 can promote the synthesis of collagen IV, XVII and the like, so that the structure of the epidermal layer and the dermis connecting layer is more stable, the flat or sunken basement membrane structure is repaired, the signal channel between true epidermis is improved, and a faster nutrition channel is further provided for improving the fiber structure of the dermis.

In the aspect of the dermis, the invention selects the micromolecule hydrolyzed collagen with the molecular weight less than 3000Da, the micromolecule hydrolyzed collagen can quickly permeate into the dermis from the epidermal layer, the synthesis of type I and type III collagen is promoted, the continuous nutrition supplement is carried out on the dermis, and the invention has very remarkable effect on the recovery of the collagen fiber structure of the dermis. In addition, the acetyl tetrapeptide-2 can induce the synthesis of type I collagen, most importantly, the synthesis of elastin in a dermis layer is further promoted, elastic fibers in the dermis layer are further repaired, the distance between the elastic fibers is increased, the skin is enabled to be full, the skin compactness is improved, and the skin elasticity is recovered.

Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.

Drawings

The accompanying drawings, which are included to provide a further understanding of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the principles of the invention:

FIG. 1 is a graph showing the results of wrinkle depth reduction tests of examples 1 to 5, blank examples, and comparative examples 1 to 4;

FIG. 2 is a graph showing the results of the wrinkle area reduction test of examples 1 to 5, blank examples and comparative examples 1 to 4;

FIG. 3 is a graph showing the results of the skin elasticity improvement test of examples 1 to 5, the blank example and comparative examples 1 to 4;

FIG. 4 is a graphical representation of the wrinkle depth reduction test results of example 3 and comparative examples 5-8;

FIG. 5 is a graphical representation of the wrinkle area reduction test results of example 3 and comparative examples 5-8;

FIG. 6 is a graph showing the results of the skin elasticity improvement test of example 3 and comparative examples 5 to 8;

FIG. 7 is a graphical representation of the wrinkle depth reduction test results of example 3 and comparative examples 9-11;

FIG. 8 is a graph showing the results of the wrinkle area reduction test of example 3 and comparative examples 9 to 11;

FIG. 9 is a graph showing the results of the skin elasticity improvement test of example 3 and comparative examples 9 to 11;

FIG. 10 is a graphical representation of the wrinkle depth reduction test results of example 3 and comparative examples 12-13;

FIG. 11 is a graph showing the results of the wrinkle area reduction test of example 3 and comparative examples 12 to 13;

fig. 12 is a graph showing the results of the skin elasticity improvement test of example 3 and comparative examples 12 to 13.

In the figure: in the schematic representation of the same test sample, from left to right are the test results for days 7, 14 and 28, respectively.

Detailed Description

For a fuller understanding of the technical aspects of the present invention, reference should be made to the following detailed description taken together with the accompanying drawings; it is to be understood that the described embodiments are merely a subset of the embodiments of the invention, and not all embodiments; all other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

The features, benefits and advantages of the present invention will become apparent to those skilled in the art from a reading of the present disclosure.

All percentages, parts and ratios are based on the total weight of the composition of the present invention, unless otherwise specified. The term "weight content" herein may be represented by the symbol "%".

The use of "including," "comprising," "containing," "having," or other variations thereof herein, is meant to encompass the non-exclusive inclusion, as such terms are not to be construed. The term "comprising" means that other steps and ingredients can be added that do not affect the end result. The term "comprising" also includes the terms "consisting of and" consisting essentially of. The compositions and methods/processes of the present invention can comprise, consist of, and consist essentially of the essential elements and limitations described herein, as well as any of the additional or optional ingredients, components, steps, or limitations described herein.

It should be noted that the essence and the preservative are conventional additives in the cosmetic technical field, and the amount thereof can be added by those skilled in the art according to the content recorded in the present invention and the related regulations, according to the design requirements of the product.

Examples 1 to 5 and comparative examples 1 to 4

The cosmetics of examples 1 to 5 and comparative examples 1 to 4 were formulated according to the formulation composition in the following table 1, and specifically, the cosmetics were anti-wrinkle tightening lotions.

Table 1: formulation compositions (%)

The preparation methods of the anti-wrinkle firming skin moisturizers of examples 1 to 5 and comparative examples 1 to 4 comprise the following steps:

3. cooling to 45 ℃, adding the preservative and the essence, then adding the glycerol glucoside, the hexapeptide-9, the acetyl tetrapeptide-2 and the hydrolyzed collagen, and stirring for 10 minutes until the mixture is uniform, thus obtaining the anti-wrinkle firming skin lotion.

Tests prove that in the embodiment, the humectant can also be one or more of propylene glycol, butanediol, dipropylene glycol, isoprene glycol, 1, 3-propanediol, methyl propylene glycol, polyethylene glycol-32, methyl gluceth-20 and glyceryl polyether-26.

The thickener can also be one or more of ammonium acryloyl dimethyl taurate/VP copolymer, hydroxyethyl cellulose, sodium polyacrylate, sodium acrylate/sodium acryloyldimethyl taurate copolymer, cetearyl alcohol, cetyl alcohol, and behenyl alcohol.

The pH regulator may also be one or more of triethanolamine and inorganic alkali.

Wrinkle resistance test and elasticity test:

20 test subjects aged 30 to 60 years, whose eyes and cheeks were the subject parts (same region and area), and subjects of the same degree of wrinkle level were the subjects, and one side was randomly used as the sample-applied part and the other side was used as the non-applied part, and the applied part was continuously used with the test sample for 28 days.

The PROMIS system analysis was used clinically to assess the percent reduction in tail-eye wrinkle depth, wrinkle area for 7 days, 14 days, 28 days.

The percent increase in skin elasticity was measured on the cheek area for 7, 14, and 28 days using a skin elasticity tester ELASTIMETER ELM 1086.

The anti-wrinkle tightening lotions of examples 1 to 5, the blank examples and comparative examples 1 to 4 were tested according to the anti-wrinkle test and elasticity test methods, and the test results are shown in fig. 1 to 3; in the figure: in the schematic representation of the same test sample, from left to right are the test results for days 7, 14 and 28, respectively.

As can be seen from the test results of fig. 1 to 3, examples 1 to 5 according to the present invention are significantly superior to the blank control group in the wrinkle depth, wrinkle area reduction and skin elasticity improvement through the use test for 7 days to 14 days to 28 days, compared to the blank example.

The effects of comparative examples 1 to 5 and comparative examples 1 to 4 were further analyzed:

comparative example 1 excludes glycerol glucoside, which is an ingredient for promoting epidermal cell moisturizing, regeneration and proliferation, and the addition amount of the remaining hexapeptide-9, acetyl tetrapeptide-2 and hydrolyzed collagen in the composition is increased to 4 times that of example 1 or 2 times that of example 3.

Comparative example 2 was to remove the anti-wrinkle component hexapeptide-9 of the true epidermal junction layer and to increase the amount of the remaining three components of glycerol glucoside, acetyl tetrapeptide-2, and hydrolyzed collagen to 4 times that of example 1 or 2 times that of example 3.

Comparative example 3 excludes hydrolyzed collagen that promotes collagen synthesis in the dermis layer, and the amount of the remaining three components of glycerol glucoside, hexapeptide-9, and acetyl tetrapeptide-2 in the composition was increased to 4 times that of example 1 or 2 times that of example 3.

Comparative example 4 excludes acetyl tetrapeptide-2, which promotes elastin synthesis in the dermis layer, and the amounts of the remaining three components, namely glycerol glucoside, hexapeptide-9 and hydrolyzed collagen, in the composition are increased to 4 times that of example 1 or 2 times that of example 3.

From the results, it can be seen that: the anti-wrinkle and firming composition components of the epidermal layer, the real epidermal connecting layer and the dermal layer in the composition of each embodiment of the invention complement each other in anti-wrinkle mechanism, have the mutual synergistic and mutually-promoting effects, and are obviously superior to each proportion in the aspects of improving wrinkle depth, wrinkle area and skin elasticity.

Comparing example 1 with comparative example 1, comparative example 1 needs to increase the addition amount of the other three components to 4 times or more after removing the glycerol glucoside component which can promote the regeneration and proliferation of epidermal cell moisturizing, and comparative example 1 still fails to achieve the effect of example 1 on the improvement of wrinkle depth, wrinkle area and skin elasticity. The improvement of the wrinkles is not only related to the repair of the dermis, the metabolism of the epidermis is accelerated, and the cell repair and proliferation of the epidermis are promoted, so that the wrinkle-removing cream has very important effects on comprehensive wrinkle removal.

Further comparing example 3 with comparative example 2, the addition amount of glyceryl glucoside, acetyl tetrapeptide-2, and hydrolyzed collagen in comparative example 2 was 2 times of that of example 3, but the nutrition of the epidermal layer and the dermal layer connecting layer could not be rapidly and effectively delivered by permeation due to the lack of hexapeptide-9, which is an effective ingredient capable of repairing the basement membrane, and the true effect of the anti-wrinkle active substance could not be fully exerted.

In comparative example 3, the addition amount of the three components of glycerol glucoside, hexapeptide-9 and acetyl tetrapeptide-2 was increased to 2 times that of example 3, but the effects of example 3 on the improvement of wrinkle depth, wrinkle area and skin elasticity of comparative example 3 were not achieved due to the lack of hydrolyzed collagen which can promote the synthesis of collagen in the dermis layer. Similarly, the addition amount of the three components of glycerol glucoside, hexapeptide-9 and hydrolyzed collagen in comparative example 4 was increased to 2 times that of example 3, but the improvement of wrinkle depth, wrinkle area and skin elasticity in comparative example 4 due to the absence of acetyl tetrapeptide-2, which promotes the synthesis of elastin in the dermis, was also not achieved with the effect of example 3. The improvement of the wrinkles is not only related to the repair of the epidermis layer and the basement membrane and promotes the synthesis of collagen and elastin in the dermis layer, but also plays a very important role in overall wrinkle resistance.

In consideration of the specificity of the molecular structure of glycerol glucoside, the present invention further uses glycerol, sucrose, and polysaccharides such as β -glucan, mannan, etc. in place of glycerol glucoside in equivalent amount in example 3.

Example 3, comparative examples 5 to 8

The cosmetics of example 3 and comparative examples 5 to 8, specifically, anti-wrinkle and tightening skin lotions were formulated according to the formulation compositions in table 2 below.

Table 2: formulation composition (%)

The preparation method of the anti-wrinkle firming skin moisturizer is the same as the preparation method of the anti-wrinkle firming skin moisturizer in the embodiment 1.

The anti-wrinkle tightening lotions of example 3 and comparative examples 5 to 8 were tested according to the anti-wrinkle test and elasticity test methods, and the test results are shown in fig. 4 to 6; in the figure: in the schematic representation of the same test sample, from left to right are the test results for days 7, 14 and 28, respectively.

The results of the tests according to fig. 4-6 can be found: comparative example 5, which replaces glycerol glucoside with 2% glycerol in equal amounts, showed a significant reduction in the improvement of wrinkle depth, wrinkle area, and skin elasticity, compared to example 3. Although glycerin has a good water-retaining property, it does not have a significant effect of improving wrinkles and increasing skin elasticity.

Further, it can be seen that comparative examples 6 to 8 equally replace glyceroglucoside with sugars such as sucrose, β -glucan, mannan, etc., respectively, while the β -glucan of comparative example 7 also exhibits certain anti-wrinkle and skin elasticity improving effects. This is because β -glucan is also able to give the stratum corneum direct and effective nutritional supplementation, which increases the regenerative capacity of damaged skin cells. However, the effect of β -glucan on improving wrinkle area, wrinkle depth, and skin elasticity is still different from that of the present invention when added in the same amount, and this is probably because the molecular space structure of the present invention is smaller and more easily absorbed and utilized by the skin than β -glucan.

On the basis of the embodiment 3, the invention further screens and compares the influence of the anti-wrinkle polypeptides commonly used in the market on the test result. Example 3 and comparative examples 9-11 are specifically as follows:

comparative example 9, acetyl tetrapeptide-2 of example 3 of the present invention was equally replaced with palmitoyl tetrapeptide-5;

comparative example 10, acetyl hexapeptide-8 was used in place of acetyl tetrapeptide-2 in example 3 of the present invention in equal amounts;

comparative example 11, acetyl octapeptide-3 was used in place of acetyl tetrapeptide-2 in inventive example 3 in equal amounts.

Example 3, comparative examples 9 to 11

The cosmetics of example 3 and comparative examples 9 to 11, specifically, anti-wrinkle tightening lotions, were formulated according to the formulation compositions in table 3 below.

The anti-wrinkle tightening lotions of example 3 and comparative examples 9 to 11 were tested according to the anti-wrinkle test and elasticity test methods, and the test results are shown in fig. 7 to 9; in the figure: in the schematic representation of the same test sample, from left to right are the test results for days 7, 14 and 28, respectively.

The results of the tests according to FIGS. 7-9 may give: different kinds of polypeptides show certain wrinkle improvement and skin elasticity improvement effects in practical tests, but the specific wrinkle improvement effects are different.

Further comparison shows that comparative example 9, which is also palmitoyl tetrapeptide-5, which is a tetrapeptide, has a good effect of improving skin elasticity, but has a certain difference from acetyl tetrapeptide-2 of the present invention. While the same acetylated peptides such as acetyl hexapeptide-8 and acetyl octapeptide-3 have certain wrinkle area and depth improving effect after being added in equal amount, when the product is used for 28 days, the effect of improving skin elasticity is very limited in comparative examples 10 and 11 when the product is used for 14 to 28 days, compared with example 3 of the present invention, probably because the acetyl hexapeptide-8 and acetyl octapeptide-3 mainly aim at improving expression lines caused by muscle contraction, while the acetyl tetrapeptide-2 of the present invention can not only induce type I collagen synthesis, but most importantly promote the synthesis of dermal elastin, further repair dermal elastic fibers, increase the space between elastic fibers, make the skin more plump, improve skin firmness, and restore skin elasticity.

Through the screening and comparative tests of different kinds of polypeptides, the acetyl tetrapeptide-2 used in the invention focuses on improving the elastic fiber structure of the dermis, has better skin elasticity improving effect than other polypeptides, and forms an overall synergistic anti-wrinkle scheme with other three active substances (glycerol glucoside, hexapeptide-9 and hydrolyzed collagen) in the invention on an anti-wrinkle mechanism, and the components supplement each other and have irreplaceability.

Further, the present invention further compares the effect of collagen of different molecular weights on the test effect on the basis of example 3.

Comparative example 12 the hydrolyzed collagen of example 3 of the invention was replaced by an equal amount of soluble collagen (molecular weight of about 50000 Da).

Comparative example 13, an equivalent amount of a soluble collagen polymer (molecular weight > 100000Da) was used in place of the hydrolyzed collagen of example 3 of the present invention.

Example 3, comparative examples 12 to 13

The cosmetics of example 3 and comparative examples 12 to 13, specifically, anti-wrinkle tightening lotions, were formulated according to the formulation compositions in table 4 below.

The anti-wrinkle tightening lotions of example 3 and comparative examples 12 to 13 were tested according to the anti-wrinkle test and elasticity test methods, and the test results are shown in fig. 10 to 12; in the figure: in the schematic representation of the same test sample, from left to right are the test results for days 7, 14 and 28, respectively.

The results of the tests according to FIGS. 10-12 may give: in the invention, the collagen with small molecular weight has better effect of improving skin wrinkles and skin elasticity under the condition of the same addition amount. Compared with soluble collagen with medium molecules and high-molecular soluble collagen polymers, the hydrolyzed collagen with smaller molecular weight is used in the invention, can quickly permeate from the epidermal layer to the dermal layer, promotes the synthesis of type I and type III collagen, carries out continuous nutrition supplement for the dermal layer, and has more remarkable effect on the recovery of the collagen fiber structure of the dermal layer.

In conclusion, the invention starts from the mechanism of wrinkle generation, specifically selects and compares various anti-wrinkle active substances from a plurality of surfaces such as an epidermal layer, a true epidermal connecting layer, a dermal layer and the like, further screens out a comprehensive anti-wrinkle compact composition with more comprehensive overall mechanism and more obvious effect through component optimization, and can achieve the effects of improving wrinkles and skin elasticity more quickly, continuously and effectively.

Furthermore, the anti-wrinkle tightening skin lotion can be prepared into cosmetics in other dosage forms, such as anti-wrinkle tightening skin lotion, anti-wrinkle tightening skin cream, anti-wrinkle tightening skin gel, anti-wrinkle tightening skin spray and the like.

When the cosmetic formulation is anti-wrinkle tightening skin care emulsion, anti-wrinkle tightening skin care cream or anti-wrinkle tightening skin care gel, a person skilled in the art can properly add the emulsifier according to the actual product design and relevant regulations; wherein the emulsifier can be conventional emulsifier in cosmetic field; preferably, the emulsifier can be one or more of glyceryl stearate, PEG-40 sorbitan stearate, PEG-100 stearate, and polysorbate-20.

The technical solutions provided by the embodiments of the present invention are described in detail above, and the principles and embodiments of the present invention are explained herein by using specific examples, and the descriptions of the embodiments are only used to help understanding the principles of the embodiments of the present invention; meanwhile, for a person skilled in the art, according to the embodiments of the present invention, there may be variations in the specific implementation manners and application ranges, and in summary, the content of the present description should not be construed as a limitation to the present invention.

Claims

1. The anti-wrinkle firming composition is characterized by comprising the following components in parts by weight:

glycerol glucoside: 0.5-2 parts;

hexapeptide-9: 1-5 parts;

acetyl tetrapeptide-2: 0.5-2 parts;

hydrolyzing collagen: 0.5-2 parts;

the hydrolyzed collagen has a molecular weight of less than 3000 Da.

2. The anti-wrinkle tightening composition according to claim 1, which is prepared from the following components in parts by weight:

glycerol glucoside: 1-2 parts;

hexapeptide-9: 2-4 parts;

acetyl tetrapeptide-2: 1-2 parts;

hydrolyzing collagen: 1-2 parts.

3. The anti-wrinkle tightening composition according to claim 1 or 2, wherein the weight ratio of acetyl tetrapeptide-2 to hydrolyzed collagen is 1: 1.

4. A cosmetic comprising the anti-wrinkle tightening composition according to any one of claims 1 to 3, wherein the anti-wrinkle tightening composition is present in the cosmetic in an amount of 2.5 to 10% by weight.

5. The cosmetic according to claim 4, further comprising 90 to 97.5% by weight of a cosmetic adjuvant base.

6. The cosmetic according to claim 5, wherein the cosmetic auxiliary base is selected from one or more of a humectant, a thickener, a pH regulator, an emulsifier, a preservative, a fragrance, and water.

7. The cosmetic according to claim 6, wherein the humectant is selected from one or more of glycerin, propylene glycol, butylene glycol, dipropylene glycol, isoprene glycol, 1, 3-propanediol, methyl propanediol, polyethylene glycol-32, methyl gluceth-20, glyceryl polyether-26.

8. Cosmetic product according to claim 6, characterized in that the thickening agent is chosen from one or more of carbomer, xanthan gum, ammonium acryloyldimethyltaurate/VP copolymer, hydroxyethylcellulose, sodium polyacrylate, sodium acrylate/sodium acryloyldimethyltaurate copolymer, cetearyl alcohol, cetyl alcohol, behenyl alcohol.

9. The cosmetic according to claim 6, wherein the pH regulator is one or more selected from arginine, triethanolamine and inorganic bases.

10. The cosmetic according to claim 6, wherein the preservative is selected from one or more of methylparaben, phenoxyethanol, propylparaben; the essence is selected from one or more of faint scent essence, floral essence, fruity essence and composite scent essence.