CN113599338A - NMN-containing anti-aging essence and preparation method thereof - Google Patents

NMN-containing anti-aging essence and preparation method thereof Download PDF

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CN113599338A
CN113599338A CN202110936355.1A CN202110936355A CN113599338A CN 113599338 A CN113599338 A CN 113599338A CN 202110936355 A CN202110936355 A CN 202110936355A CN 113599338 A CN113599338 A CN 113599338A
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parts
nmn
extract
essential oil
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黄瑞云
张雄强
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Jinyun Pharmaceutical Foshan Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9771Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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Abstract

The invention discloses NMN-containing anti-aging essence which comprises the following raw materials in parts by weight: 1000 parts of deionized water and 1500 parts of aloe gel, 50-80 parts of aloe gel, 20-45 parts of propylene glycol, 10-22 parts of ginkgo leaf extract, 12-25 parts of caulis spatholobi extract, 3-5 parts of nicotinamide, 20-50 parts of glycerol, 5-8 parts of isopropyl palmitate, 4-7 parts of glycerol stearate, 12-16 parts of almond essential oil, 13-18 parts of jasmine essential oil, 15-25 parts of emulsifier, 3-5 parts of tocopherol, 2-8 parts of nicotinamide mononucleotide, 2-6 parts of nucleotide compound, 12-25 parts of active peptide, 2-4 parts of polydimethylsiloxane, 8-20 parts of anti-inflammatory repairing agent, 10-25 parts of humectant, 2-5 parts of preservative and 2-5 parts of antioxidant; also discloses a preparation method of the NMN-containing anti-aging essence, which comprises the following steps: firstly, weighing the raw materials of the components in parts by weight. The invention can obviously enhance the cell vitality, enhance the compaction degree of the skin, reform the skin and improve the microcirculation, thereby achieving the effects of skin vitality and anti-aging.

Description

NMN-containing anti-aging essence and preparation method thereof
Technical Field
The invention relates to the technical field of anti-aging essence, and particularly relates to NMN-containing anti-aging essence and a preparation method thereof.
Background
Skin aging is a progressive physiological process and also a result of the combined action of various factors such as heredity, environment, psychology and the like. With the improvement of living standard of people, the functional requirements on skin care products are higher and higher, and skin care products with anti-aging effect are also in the endlessly.
NMN, all known as β -nicotinamide mononucleotide, is a precursor for the synthesis of the life factor NAD +. NAD + molecules are an important support for cell viability, and need to be converted by supplementation with NMN, since NAD + cannot be directly absorbed by the human body. The daily food contains a small amount of NMN, but the NMN is far from being needed by the human body, and the NMN is considered to have the effects of delaying senility, improving the immunity of the body and the like, so the NMN food has the advantages of being simple in structure, convenient to use and low in cost. An anti-aging essence containing NMN is designed.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides NMN-containing anti-aging essence and a preparation method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
an anti-aging essence containing NMN comprises the following raw materials in parts by weight: 1000 parts of deionized water and 1500 parts of aloe gel, 50-80 parts of aloe gel, 20-45 parts of propylene glycol, 10-22 parts of ginkgo leaf extract, 12-25 parts of caulis spatholobi extract, 3-5 parts of nicotinamide, 20-50 parts of glycerol, 5-8 parts of isopropyl palmitate, 4-7 parts of glycerol stearate, 12-16 parts of almond essential oil, 13-18 parts of jasmine essential oil, 15-25 parts of emulsifier, 3-5 parts of tocopherol, 2-8 parts of nicotinamide mononucleotide, 2-6 parts of nucleotide compound, 12-25 parts of active peptide, 2-4 parts of polydimethylsiloxane, 8-20 parts of anti-inflammatory repairing agent, 10-25 parts of humectant, 2-5 parts of preservative and 2-5 parts of antioxidant.
Preferably, the feed comprises the following raw materials in parts by weight: 1400 parts of deionized water, 60-70 parts of aloe gel, 30-40 parts of propylene glycol, 12-20 parts of ginkgo leaf extract, 15-20 parts of caulis spatholobi extract, 3.5-4.5 parts of nicotinamide, 25-45 parts of glycerol, 6-7 parts of isopropyl palmitate, 5-6 parts of glycerol stearate, 13-15 parts of almond essential oil, 14-17 parts of jasmine essential oil, 18-23 parts of emulsifier, 3.5-4.5 parts of tocopherol, 3-6 parts of nicotinamide mononucleotide, 3-5 parts of nucleotide compound, 15-20 parts of active peptide, 2.5-3.5 parts of polydimethylsiloxane, 10-15 parts of anti-inflammatory repairing agent, 13-22 parts of humectant, 3-4.5 parts of preservative and 3-4.5 parts of antioxidant.
Preferably, the feed comprises the following raw materials in parts by weight: 1300 parts of deionized water, 65 parts of aloe gel, 35 parts of propylene glycol, 16 parts of ginkgo leaf extract, 18 parts of caulis spatholobi extract, 4 parts of nicotinamide, 35 parts of glycerol, 6.5 parts of isopropyl palmitate, 5.5 parts of glycerol stearate, 14 parts of almond essential oil, 16 parts of jasmine essential oil, 20 parts of emulsifier, 4 parts of tocopherol, 5 parts of nicotinamide mononucleotide, 4 parts of nucleotide compound, 18 parts of active peptide, 3 parts of polydimethylsiloxane, 13 parts of anti-inflammatory repair agent, 15 parts of humectant, 4 parts of preservative and 4 parts of antioxidant.
Preferably, the active peptides comprise palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide.
Preferably, the humectant is one or more of diglycerin, beta-glucan, spirulina maxima extract, sodium pyrrolidone carboxylate and lactic acid.
Preferably, the antioxidant is one or more of tea polyphenol, rhodiola rosea extract, liquorice extract and centella extract.
Preferably, the preservative is one or more of 1, 2-hexanediol, ethylhexyl glycerol and p-hydroxyacetophenone.
Preferably, the anti-inflammatory repairing agent is one or more of hydrolyzed collagen, hydroxyphenylpropionamide benzoic acid, allantoin, ceramide 1 and ceramide 2.
Preferably, the emulsifier is one or more of lecithin, lanolin alcohol, lanolin acid, and beeswax.
A preparation method of NMN-containing anti-aging essence comprises the following steps:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 40-45 ℃, and stirring for 15-25min at the rotating speed of 5000-;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 50-60 ℃, and stirring for 15-25min at the rotating speed of 7000-8000r/min to obtain a mixture B;
pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 35-40 ℃, keeping the homogenization for 10-20min, keeping the temperature for 20-30min, cooling and standing for 20-24h to obtain essence, and discharging the essence.
The invention has the beneficial effects that:
1. through the addition of nicotinamide mononucleotide, namely NMN, a nucleotide compound, NMN is a precursor for synthesizing NAD + in a human body, and NAD + is indirectly or directly supplied to skin tissues and epidermal cells. It is reported that NAD + is an indispensable coenzyme component of hundreds of enzyme proteins including longevity enzyme protein in human body, plays a fundamental role in human health, and the addition of NMN can obviously enhance cell activity, thereby achieving the anti-aging effect.
2. By adding active peptides, palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide, the active peptides easily penetrate through the skin epidermal barrier and are absorbed and utilized, the dipeptide can protect a DNA structure, resist oxidation and saccharification and effectively promote the growth of collagen, the tripeptide can enhance the compaction degree of the skin and stimulate the synthesis of glucosamine and collagen, the tetrapeptide can reform the skin, improve microcirculation and reduce the damage of ultraviolet rays, the pentapeptide can increase the thickness of the skin and enhance the disease resistance, the moisture content of the skin is improved, the hexapeptide effectively improves the vitality of the skin, helps a human body to reconstruct a dermal tissue and promotes cell regeneration.
3. By adding aloe gel, propylene glycol, folium Ginkgo extract, caulis Spatholobi extract, and nicotinamide, the product has effects of keeping moisture, resisting oxidation, increasing cell activity, and promoting cell proliferation.
Detailed Description
The technical solutions in the embodiments of the present invention are clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments.
Example one
An anti-aging essence containing NMN comprises the following raw materials in parts by weight: 1000 parts of deionized water, 50 parts of aloe gel, 20 parts of propylene glycol, 10 parts of ginkgo leaf extract, 12 parts of caulis spatholobi extract, 3 parts of nicotinamide, 20 parts of glycerol, 5 parts of isopropyl palmitate, 4 parts of glycerol stearate, 12 parts of almond essential oil, 13 parts of jasmine essential oil, 15 parts of emulsifier, 3 parts of tocopherol, 2 parts of nicotinamide mononucleotide, 2 parts of nucleotide compound, 12 parts of active peptide, 2 parts of polydimethylsiloxane, 8 parts of anti-inflammatory repairing agent, 10 parts of humectant, 2 parts of preservative and 2 parts of antioxidant.
Specifically, the active peptides comprise palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide.
Specifically, the humectant is diglycerol, the antioxidant is tea polyphenol, the preservative is 1, 2-hexanediol, the anti-inflammatory repairing agent is hydrolyzed collagen, and the emulsifier is one or more of lecithin, lanolin alcohol, lanolin acid and beeswax.
A preparation method of NMN-containing anti-aging essence comprises the following steps:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 40 ℃, and stirring for 15min at the rotating speed of 5000r/min to obtain a mixture A;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 50 ℃, and stirring for 15min at the rotating speed of 7000r/min to obtain a mixture B;
and fourthly, pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 35 ℃, keeping the homogenization for 10min, keeping the temperature for 20min, cooling and standing for 20h to obtain essence, and discharging the essence.
Example two
An anti-aging essence containing NMN comprises the following raw materials in parts by weight: 1200 parts of deionized water, 60 parts of aloe gel, 30 parts of propylene glycol, 12 parts of ginkgo leaf extract, 15 parts of caulis spatholobi extract, 3.5 parts of nicotinamide, 25 parts of glycerol, 6 parts of isopropyl palmitate, 5 parts of glycerol stearate, 13 parts of almond essential oil, 14 parts of jasmine essential oil, 18 parts of emulsifier, 3.5 parts of tocopherol, 3 parts of nicotinamide mononucleotide, 3 parts of nucleotide compound, 15 parts of active peptide, 2.5 parts of polydimethylsiloxane, 10 parts of anti-inflammatory repairing agent, 13 parts of humectant, 3 parts of preservative and 3 parts of antioxidant.
Specifically, the active peptide comprises palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide, the humectant is beta-glucan, the antioxidant is a rhodiola rosea extract, the preservative is ethylhexyl glycerol, the anti-inflammatory repairing agent is hydroxyphenyl propionamide benzoic acid, and the emulsifier is lanolin.
A preparation method of NMN-containing anti-aging essence comprises the following steps:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 42 ℃, and stirring for 18min at the rotating speed of 5200r/min to obtain a mixture A;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 52 ℃, and stirring for 17min at the rotating speed of 7200r/min to obtain a mixture B;
and fourthly, pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 37 ℃, keeping the homogenization for 12min, keeping the temperature for 22min, cooling and standing for 22h to obtain essence, and discharging the essence.
EXAMPLE III
An anti-aging essence containing NMN comprises the following raw materials in parts by weight: 1300 parts of deionized water, 65 parts of aloe gel, 35 parts of propylene glycol, 16 parts of ginkgo leaf extract, 18 parts of caulis spatholobi extract, 4 parts of nicotinamide, 35 parts of glycerol, 6.5 parts of isopropyl palmitate, 5.5 parts of glycerol stearate, 14 parts of almond essential oil, 16 parts of jasmine essential oil, 20 parts of emulsifier, 4 parts of tocopherol, 5 parts of nicotinamide mononucleotide, 4 parts of nucleotide compound, 18 parts of active peptide, 3 parts of polydimethylsiloxane, 13 parts of anti-inflammatory repair agent, 15 parts of humectant, 4 parts of preservative and 4 parts of antioxidant.
Specifically, the active peptide comprises palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide, the humectant is a maximum spirulina extract, the antioxidant is a liquorice extract, the preservative is ethylhexyl glycerol, the anti-inflammatory repairing agent is allantoin, and the emulsifier is one or more of lecithin, lanolin alcohol, lanolin acid and beeswax.
A preparation method of NMN-containing anti-aging essence comprises the following steps:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 43 ℃, and stirring for 20min at the rotating speed of 5500r/min to obtain a mixture A;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 55 ℃, and stirring for 20min at the rotating speed of 7500r/min to obtain a mixture B;
and fourthly, pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 39 ℃, keeping the homogenization for 15min, keeping the temperature for 26min, cooling and standing for 23h to obtain essence, and discharging the essence.
Example four
An anti-aging essence containing NMN comprises the following raw materials in parts by weight: 1400 parts of deionized water, 70 parts of aloe gel, 40 parts of propylene glycol, 20 parts of ginkgo leaf extract, 20 parts of caulis spatholobi extract, 4.5 parts of nicotinamide, 45 parts of glycerol, 7 parts of isopropyl palmitate, 6 parts of glycerol stearate, 15 parts of almond essential oil, 17 parts of jasmine essential oil, 23 parts of emulsifier, 4.5 parts of tocopherol, 6 parts of nicotinamide mononucleotide, 5 parts of nucleotide compound, 20 parts of active peptide, 3.5 parts of polydimethylsiloxane, 15 parts of anti-inflammatory repair agent, 22 parts of humectant, 4.5 parts of preservative and 4.5 parts of antioxidant.
Specifically, the active peptides comprise palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide, the humectant is diglycerol, spirulina maxima extract and sodium pyrrolidone carboxylate, the antioxidant is tea polyphenol and rhodiola rosea extract, the preservative is 1, 2-hexanediol and p-hydroxyacetophenone, the anti-inflammatory repairing agent is hydrolyzed collagen, ceramide 1 and ceramide 2, and the emulsifier is lecithin, lanolin and lanolin.
A preparation method of NMN-containing anti-aging essence comprises the following steps:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 44 ℃, and stirring for 22min at the rotating speed of 6200r/min to obtain a mixture A;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 58 ℃, and stirring for 23min at the rotating speed of 7800r/min to obtain a mixture B;
and fourthly, pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 38 ℃, keeping the homogenization for 18min, keeping the temperature for 28min, cooling and standing for 23h to obtain essence, and discharging the essence.
EXAMPLE five
An anti-aging essence containing NMN comprises the following raw materials in parts by weight: 1500 parts of deionized water, 80 parts of aloe gel, 45 parts of propylene glycol, 22 parts of ginkgo leaf extract, 25 parts of caulis spatholobi extract, 5 parts of nicotinamide, 50 parts of glycerol, 8 parts of isopropyl palmitate, 7 parts of glycerol stearate, 16 parts of almond essential oil, 18 parts of jasmine essential oil, 25 parts of emulsifier, 5 parts of tocopherol, 8 parts of nicotinamide mononucleotide, 6 parts of nucleotide compound, 25 parts of active peptide, 4 parts of polydimethylsiloxane, 20 parts of anti-inflammatory repairing agent, 25 parts of humectant, 5 parts of preservative and 5 parts of antioxidant.
Specifically, the active peptide comprises palmitoyl hexapeptide-3, human oligopeptide-1, dipeptide, tripeptide, tetrapeptide and hexapeptide, the humectant is diglycerol and lactic acid, the antioxidant is an asiatic pennywort herb extract, the preservative is p-hydroxyacetophenone, the anti-inflammatory repairing agent is ceramide 1 and ceramide 2, and the emulsifier is wool acid and beeswax.
A preparation method of NMN-containing anti-aging essence comprises the following steps:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 45 ℃, and stirring for 25min at the rotating speed of 6500r/min to obtain a mixture A;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 60 ℃, and stirring for 25min at the rotating speed of 8000r/min to obtain a mixture B;
and fourthly, pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 40 ℃, keeping the homogenization for 20min, keeping the temperature for 30min, cooling and standing for 24h to obtain essence, and discharging the essence.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.

Claims (10)

1. The NMN-containing anti-aging essence is characterized by comprising the following raw materials in parts by weight: 1000 parts of deionized water and 1500 parts of aloe gel, 50-80 parts of aloe gel, 20-45 parts of propylene glycol, 10-22 parts of ginkgo leaf extract, 12-25 parts of caulis spatholobi extract, 3-5 parts of nicotinamide, 20-50 parts of glycerol, 5-8 parts of isopropyl palmitate, 4-7 parts of glycerol stearate, 12-16 parts of almond essential oil, 13-18 parts of jasmine essential oil, 15-25 parts of emulsifier, 3-5 parts of tocopherol, 2-8 parts of nicotinamide mononucleotide, 2-6 parts of nucleotide compound, 12-25 parts of active peptide, 2-4 parts of polydimethylsiloxane, 8-20 parts of anti-inflammatory repairing agent, 10-25 parts of humectant, 2-5 parts of preservative and 2-5 parts of antioxidant.
2. The NMN-containing anti-aging essence according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 1400 parts of deionized water, 60-70 parts of aloe gel, 30-40 parts of propylene glycol, 12-20 parts of ginkgo leaf extract, 15-20 parts of caulis spatholobi extract, 3.5-4.5 parts of nicotinamide, 25-45 parts of glycerol, 6-7 parts of isopropyl palmitate, 5-6 parts of glycerol stearate, 13-15 parts of almond essential oil, 14-17 parts of jasmine essential oil, 18-23 parts of emulsifier, 3.5-4.5 parts of tocopherol, 3-6 parts of nicotinamide mononucleotide, 3-5 parts of nucleotide compound, 15-20 parts of active peptide, 2.5-3.5 parts of polydimethylsiloxane, 10-15 parts of anti-inflammatory repairing agent, 13-22 parts of humectant, 3-4.5 parts of preservative and 3-4.5 parts of antioxidant.
3. The NMN-containing anti-aging essence according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 1300 parts of deionized water, 65 parts of aloe gel, 35 parts of propylene glycol, 16 parts of ginkgo leaf extract, 18 parts of caulis spatholobi extract, 4 parts of nicotinamide, 35 parts of glycerol, 6.5 parts of isopropyl palmitate, 5.5 parts of glycerol stearate, 14 parts of almond essential oil, 16 parts of jasmine essential oil, 20 parts of emulsifier, 4 parts of tocopherol, 5 parts of nicotinamide mononucleotide, 4 parts of nucleotide compound, 18 parts of active peptide, 3 parts of polydimethylsiloxane, 13 parts of anti-inflammatory repair agent, 15 parts of humectant, 4 parts of preservative and 4 parts of antioxidant.
4. The NMN-containing anti-aging essence of claim 1, wherein the active peptides comprise palmitoyl hexapeptide-3, human oligopeptide-1, dipeptides, tripeptides, tetrapeptides, and hexapeptides.
5. The NMN-containing anti-aging essence according to claim 1, wherein the moisturizer is one or more of diglycerin, beta-glucan, Spirulina maxima extract, sodium pyrrolidone carboxylate, and lactic acid.
6. The NMN-containing anti-aging essence according to claim 1, wherein the antioxidant is one or more of tea polyphenols, rhodiola rosea extract, licorice extract and centella asiatica extract.
7. The NMN-containing anti-aging essence according to claim 1, wherein the preservative is one or more of 1, 2-hexanediol, ethylhexylglycerin, and p-hydroxyacetophenone.
8. The NMN-containing anti-aging essence according to claim 1, wherein the anti-inflammatory repair agent is one or more of hydrolyzed collagen, hydroxyphenylpropionamide benzoic acid, allantoin, ceramide 1, ceramide 2.
9. The NMN-containing anti-aging essence according to claim 1, wherein the emulsifier is one or more of lecithin, lanolin alcohol, lanolin acid, and beeswax.
10. The method of claim 1, wherein the NMN-containing anti-aging essence comprises the steps of:
firstly, weighing the component raw materials in parts by weight;
secondly, heating the aloe gel, the propylene glycol, the ginkgo leaf extract, the suberect spatholobus stem extract and the nicotinamide to 40-45 ℃, and stirring for 15-25min at the rotating speed of 5000-;
thirdly, heating the glycerol, the isopropyl palmitate, the glyceryl stearate, the almond essential oil, the jasmine essential oil, the emulsifier and the tocopherol to 50-60 ℃, and stirring for 15-25min at the rotating speed of 7000-8000r/min to obtain a mixture B;
pumping the mixture A obtained in the second step and the mixture B obtained in the third step into an emulsifying pot, adding the rest of deionized water, nicotinamide mononucleotide, nucleotide compounds, active peptide, polydimethylsiloxane, anti-inflammatory repairing agent, humectant, preservative and antioxidant, homogenizing at 35-40 ℃, keeping the homogenization for 10-20min, keeping the temperature for 20-30min, cooling and standing for 20-24h to obtain essence, and discharging the essence.
CN202110936355.1A 2021-08-16 2021-08-16 NMN-containing anti-aging essence and preparation method thereof Withdrawn CN113599338A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114569518A (en) * 2022-04-15 2022-06-03 大连海洋大学 Anti-aging repairing agent and preparation method thereof
CN114748379A (en) * 2022-05-05 2022-07-15 有货(北京)信息技术有限公司 NMN-containing pure crystalline amino acid facial cleanser and preparation method thereof
CN114947090A (en) * 2022-03-24 2022-08-30 上海老滇凰生物科技有限公司 Lyophilized tablet of queen bee larva and preparation and storage method thereof
CN115192490A (en) * 2022-07-20 2022-10-18 广州睿森生物科技有限公司 Nano microemulsion NMN composition and preparation method and application thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114947090A (en) * 2022-03-24 2022-08-30 上海老滇凰生物科技有限公司 Lyophilized tablet of queen bee larva and preparation and storage method thereof
CN114569518A (en) * 2022-04-15 2022-06-03 大连海洋大学 Anti-aging repairing agent and preparation method thereof
CN114748379A (en) * 2022-05-05 2022-07-15 有货(北京)信息技术有限公司 NMN-containing pure crystalline amino acid facial cleanser and preparation method thereof
CN114748379B (en) * 2022-05-05 2023-10-24 有货(北京)信息技术有限公司 Pure crystal type amino acid facial cleanser containing NMN and preparation method thereof
CN115192490A (en) * 2022-07-20 2022-10-18 广州睿森生物科技有限公司 Nano microemulsion NMN composition and preparation method and application thereof

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