CN113498353A - 靶定b细胞成熟抗原的嵌合抗原受体和其使用方法 - Google Patents

靶定b细胞成熟抗原的嵌合抗原受体和其使用方法 Download PDF

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CN113498353A
CN113498353A CN201980079534.9A CN201980079534A CN113498353A CN 113498353 A CN113498353 A CN 113498353A CN 201980079534 A CN201980079534 A CN 201980079534A CN 113498353 A CN113498353 A CN 113498353A
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dose
cells
seq
car
bcma
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Chinese (zh)
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D·常
A·巴拉库马兰
C·A·康托
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Allogene Therapeutics Inc
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Allogene Therapeutics Inc
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CN201980079534.9A 2018-12-01 2019-11-26 靶定b细胞成熟抗原的嵌合抗原受体和其使用方法 Pending CN113498353A (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862774209P 2018-12-01 2018-12-01
US62/774209 2018-12-01
US201962816187P 2019-03-10 2019-03-10
US62/816187 2019-03-10
US201962931487P 2019-11-06 2019-11-06
US62/931487 2019-11-06
PCT/US2019/063282 WO2020112796A1 (en) 2018-12-01 2019-11-26 Chimeric antigen receptors targeting b-cell maturation antigen and methods of use thereof

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CN113498353A true CN113498353A (zh) 2021-10-12

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US (1) US20200261503A1 (https=)
EP (1) EP3886989A1 (https=)
JP (1) JP2022513691A (https=)
KR (1) KR20210099574A (https=)
CN (1) CN113498353A (https=)
AU (1) AU2019386063A1 (https=)
BR (1) BR112021010279A2 (https=)
CA (1) CA3116720A1 (https=)
CO (1) CO2021005004A2 (https=)
IL (1) IL283144A (https=)
MX (1) MX2021006395A (https=)
PE (1) PE20211915A1 (https=)
PH (1) PH12021550909A1 (https=)
SG (1) SG11202105353PA (https=)
TW (1) TW202039544A (https=)
WO (1) WO2020112796A1 (https=)

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US10294304B2 (en) 2015-04-13 2019-05-21 Pfizer Inc. Chimeric antigen receptors targeting B-cell maturation antigen
JP2024517413A (ja) 2021-04-16 2024-04-22 セルジーン コーポレーション 以前に幹細胞移植を受けた患者におけるｔ細胞療法
CN118103407A (zh) * 2021-08-12 2024-05-28 上海才致药成生物科技有限公司 一种双特异性重组蛋白及其用途
KR20240112994A (ko) 2021-11-03 2024-07-19 셀진 코포레이션 골수종을 치료하는 데 사용하기 위한 b-세포 성숙 항원에 특이적인 키메라 항원 수용체
KR20240137075A (ko) 2022-01-28 2024-09-19 주노 쎄러퓨티크스 인코퍼레이티드 세포 조성물의 제조 방법
KR20250021397A (ko) * 2022-02-09 2025-02-12 하다지트 메디칼 리서치 써비시즈 앤드 디벨롭먼트 리미티드 면역 관련 질환을 표적으로 하는 항-bcma car, 조성물 및 이의 방법
WO2023220655A1 (en) 2022-05-11 2023-11-16 Celgene Corporation Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
US20250295771A1 (en) 2022-05-11 2025-09-25 Celgene Corporation Methods and uses related to t cell therapy and production of same
EP4532695A1 (en) 2022-05-25 2025-04-09 Celgene Corporation Methods of manufacturing t cell therapies
US20250345432A1 (en) 2022-05-25 2025-11-13 Celgene Corporation Method for predicting response to a t cell therapy
WO2024097905A1 (en) 2022-11-02 2024-05-10 Celgene Corporation Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
WO2024168192A1 (en) 2023-02-10 2024-08-15 Celgene Corporation Assessment of bcma in biological samples
AU2024279278A1 (en) 2023-05-31 2025-12-18 Capstan Therapeutics, Inc. Lipid nanoparticle formulations and compositions
US20250127728A1 (en) 2023-10-05 2025-04-24 Capstan Therapeutics, Inc. Constrained Ionizable Cationic Lipids and Lipid Nanoparticles
WO2025076113A1 (en) 2023-10-05 2025-04-10 Capstan Therapeutics, Inc. Ionizable cationic lipids with conserved spacing and lipid nanoparticles
WO2025217452A1 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Constrained ionizable cationic lipids and lipid nanoparticles
WO2025217454A2 (en) 2024-04-11 2025-10-16 Capstan Therapeutics, Inc. Ionizable cationic lipids and lipid nanoparticles

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EP3131927B8 (en) * 2014-04-14 2020-12-23 Cellectis Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy
BR112017013981A2 (pt) 2015-01-26 2018-01-02 Cellectis receptores antigênicos quiméricos com uma única cadeia específicos anti-cll1 (sccars) para imunoterapia de câncer
TWI703159B (zh) * 2015-04-13 2020-09-01 美商輝瑞股份有限公司 Bcma特異性治療性抗體及其用途
US10294304B2 (en) * 2015-04-13 2019-05-21 Pfizer Inc. Chimeric antigen receptors targeting B-cell maturation antigen
TWI755547B (zh) * 2016-01-21 2022-02-21 美商輝瑞股份有限公司 靶向表皮生長因子受體變異體iii之嵌合型抗原受體

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CO2021005004A2 (es) 2021-04-30
KR20210099574A (ko) 2021-08-12
SG11202105353PA (en) 2021-06-29
PH12021550909A1 (en) 2021-12-06
MX2021006395A (es) 2021-07-15
TW202039544A (zh) 2020-11-01
WO2020112796A1 (en) 2020-06-04
PE20211915A1 (es) 2021-09-28
AU2019386063A1 (en) 2021-07-01
CA3116720A1 (en) 2020-06-04
US20200261503A1 (en) 2020-08-20
IL283144A (en) 2021-06-30
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