CN113473943B - 用于在拔牙部位保留牙槽嵴和促进颌骨再生的牙科设备 - Google Patents
用于在拔牙部位保留牙槽嵴和促进颌骨再生的牙科设备 Download PDFInfo
- Publication number
- CN113473943B CN113473943B CN202080015625.9A CN202080015625A CN113473943B CN 113473943 B CN113473943 B CN 113473943B CN 202080015625 A CN202080015625 A CN 202080015625A CN 113473943 B CN113473943 B CN 113473943B
- Authority
- CN
- China
- Prior art keywords
- screw
- dental apparatus
- socket
- dental
- cavity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000001909 alveolar process Anatomy 0.000 title claims abstract description 23
- 210000001847 jaw Anatomy 0.000 title claims abstract description 21
- 230000001737 promoting effect Effects 0.000 title claims abstract description 10
- 230000008929 regeneration Effects 0.000 title claims abstract description 8
- 238000011069 regeneration method Methods 0.000 title claims abstract description 8
- 238000000605 extraction Methods 0.000 title description 8
- 239000000463 material Substances 0.000 claims abstract description 28
- 210000000988 bone and bone Anatomy 0.000 claims abstract description 11
- 230000010478 bone regeneration Effects 0.000 claims abstract description 6
- 230000017423 tissue regeneration Effects 0.000 claims abstract description 4
- 238000000034 method Methods 0.000 claims description 15
- 239000012528 membrane Substances 0.000 claims description 14
- 230000004888 barrier function Effects 0.000 claims description 13
- 238000010079 rubber tapping Methods 0.000 claims description 8
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 7
- 239000008280 blood Substances 0.000 claims description 7
- 210000004369 blood Anatomy 0.000 claims description 7
- 229910052749 magnesium Inorganic materials 0.000 claims description 7
- 239000011777 magnesium Substances 0.000 claims description 7
- 239000000654 additive Substances 0.000 claims description 6
- 230000000996 additive effect Effects 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 210000004872 soft tissue Anatomy 0.000 claims description 5
- 208000007536 Thrombosis Diseases 0.000 claims description 4
- 239000003102 growth factor Substances 0.000 claims description 4
- 238000002844 melting Methods 0.000 claims description 4
- 230000008018 melting Effects 0.000 claims description 4
- 230000008468 bone growth Effects 0.000 claims description 3
- 239000011159 matrix material Substances 0.000 claims description 3
- 229910052751 metal Inorganic materials 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 229910052712 strontium Inorganic materials 0.000 claims description 3
- CIOAGBVUUVVLOB-UHFFFAOYSA-N strontium atom Chemical compound [Sr] CIOAGBVUUVVLOB-UHFFFAOYSA-N 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 2
- 239000003242 anti bacterial agent Substances 0.000 claims 2
- 229940088710 antibiotic agent Drugs 0.000 claims 2
- 238000001356 surgical procedure Methods 0.000 abstract description 3
- 238000002513 implantation Methods 0.000 description 6
- 229910000861 Mg alloy Inorganic materials 0.000 description 4
- 230000035876 healing Effects 0.000 description 4
- 239000007943 implant Substances 0.000 description 4
- 230000011164 ossification Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 230000008081 blood perfusion Effects 0.000 description 3
- 230000007547 defect Effects 0.000 description 3
- 210000003456 pulmonary alveoli Anatomy 0.000 description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000003115 biocidal effect Effects 0.000 description 2
- 229910010293 ceramic material Inorganic materials 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000001055 chewing effect Effects 0.000 description 2
- 210000004195 gingiva Anatomy 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- 208000006386 Bone Resorption Diseases 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229920002988 biodegradable polymer Polymers 0.000 description 1
- 239000004621 biodegradable polymer Substances 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 230000024279 bone resorption Effects 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 238000005553 drilling Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 229910001425 magnesium ion Inorganic materials 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000003990 molecular pathway Effects 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0003—Not used, see subgroups
- A61C8/0004—Consolidating natural teeth
- A61C8/0006—Periodontal tissue or bone regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0013—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy with a surface layer, coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0022—Self-screwing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0022—Self-screwing
- A61C8/0024—Self-screwing with self-boring cutting edge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0012—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy
- A61C8/0016—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the material or composition, e.g. ceramics, surface layer, metal alloy polymeric material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0031—Juxtaosseous implants, i.e. implants lying over the outer surface of the jaw bone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
- A61C8/0018—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools characterised by the shape
- A61C8/0037—Details of the shape
- A61C8/0039—Details of the shape in the form of hollow cylinder with an open bottom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
Abstract
本发明涉及一种牙科设备(1),用于在拔掉的牙齿的牙槽窝(2)周围保留牙槽嵴并促进拔掉的牙齿的牙槽窝(2)内的颌骨再生,牙科设备(1)包括:螺钉(3),所述螺钉完全由可生物降解材料制成,以消除移除手术的需要,其中螺钉(3)适于牢固固定在牙槽窝(2)中的颌骨(4)内,以防止骨组织再生期间的微运动,其中螺钉(2)的长度使得其顶部在插入状态下与牙槽窝(2)周围的牙槽嵴(5)齐平,以促进牙槽窝(2)内的完全骨再生,其中螺钉(3)具有空腔(6)和孔洞(7),其中孔洞(7)的直径基本上等于或大于20微米。
Description
技术领域
本发明涉及用于在植入前在拔牙部位保留牙槽嵴和促进颌骨再生的牙科技术。本发明更具体地涉及用于在植入前在拔掉的牙齿的牙槽窝周围保留牙槽嵴和促进拔掉的牙齿的牙槽窝内的颌骨再生的牙科设备。
背景技术
将牙种植体立即放置到新的拔牙牙槽窝中通常是不利的,因为与接续的牙槽窝愈合和植入手术相比,观察到相对较高的植入失败率。与这种接续的手术相关的问题是拔牙牙槽窝周围的牙槽嵴在愈合期间被大量吸收。在最坏的情况下,剩余的骨量不足以放置种植体。出于这个原因,提出并开发了几种牙槽嵴保留技术来减少颌骨吸收。各种各样的牙槽嵴保留技术,如用移植材料、胶原塞填充牙槽窝和用各种膜或齿龈冲头(gingiva punch)覆盖,都被证明是有效的,但效果有限。在这些牙槽嵴保留技术中,无法防止2到3毫米的横向(颊舌)变薄和1到2毫米的竖向高度损失。这些技术都缺乏保留颌骨原始形状的有效性。因此,牙科临床研究界认为完全保留牙槽嵴是不可能的。
WO 2016/134797公开了一种牙槽嵴保留技术,其中颌骨中的骨缺损用骨移植材料填充,并用生物可吸收的镁膜覆盖,其中生物可吸收膜用由镁合金制成的销、钉或螺钉固定到颌骨。在这种仅用颗粒或可模制生物材料填充缺损并放置生物可吸收膜的公知技术中,很可能发生竖向塌陷。此外,不稳定的移植材料在受到咀嚼力时会发生位移。还已知基体在组织再生期间的微运动有利于软组织而不是新骨组织的生长。此外,骨移植材料内营养灌注不良在有致密腻子的情况下尤其明显。众所周知的牙槽嵴保留技术提供有限的血液供应,因此在愈合阶段会减慢骨的生长。
发明内容
本发明的目的在于以有效的方式克服现有技术的不足,并提供一种用于在拔牙部位保留牙槽嵴和促进颌骨再生的牙科设备。
根据本发明,该牙科设备具有完全由可生物降解材料制成的螺钉,以消除对移除手术的需要。螺钉适于在牙槽窝中的颌骨内牢固固定,以防止在骨再生期间的微运动。螺钉的长度使其顶部在插入状态下与牙槽窝周围的牙槽嵴处于同一水平,以促进牙槽窝内的完全骨再生。并且螺钉具有空腔和孔洞,以允许血液灌注到空腔中以用于形成血液凝结物,以充当牙槽窝内骨生长的生物基质。
本发明的牙科设备为拔牙部位的牙槽嵴的保留和颌骨再生的促进提供了有效的技术。由于螺钉是由可生物降解材料制成的,因此它比以前用钛陶瓷材料的实验方法具有显著的优势,该钛陶瓷材料需要终生留在患者体内,并且会导致客户产生不良感受,并且引起了在种植体放置所需的通过钛陶瓷材料钻孔时产生颗粒的担忧。由于牙科设备可以像螺钉一样牢固地插入牙槽窝中,因此它在组织再生过程中为缺损部位提供了增加的稳定性,并防止软组织而不是新骨组织的生长。在这方面,与在受到咀嚼力时会位移的非稳定移植材料相比,螺钉提供了额外的优势。由于螺钉用作支柱来保持牙槽嵴的高度,因此不会发生竖向塌陷,保持了基线情况下的牙槽几何形状,防止了骨高度的损失,并且可以保持颌骨的原始形状。与使用移植材料填充膜底部的方法相比,这种好处也很有价值,因为移植材料的吸收仍会导致竖向高度的损失。由于螺钉具有空腔和孔洞,它允许血液灌注和与血凝块的紧密连接并随后促进骨再生。
根据本发明,为了覆盖对应于不同牙槽窝的深度和尺寸的各种解剖学情况,牙科设备的螺钉可以设置为不同的预定长度和直径,以允许分别调整到各个牙槽窝的深度和尺寸。从而,牙医可以根据患者的需要选择和应用牙科设备。
根据本发明,牙科设备可以由提供适当机械特性的任何类型的可吸收材料制造。例如,可以使用可生物降解的金属和/或可生物降解的聚合物。
根据本发明,螺钉的不同部分可以由具有不同成分和密度的可生物降解材料制成。因此,可以调节整个螺钉的吸收速率,以实现牙槽窝内的均匀愈合。因此,整个螺钉的机械强度也可以调节。
根据本发明,牙科设备可以由镁或镁合金制成。在这方面,由于螺钉的降解导致骨促进镁离子的聚集,因此实现了有利的效果。众所周知,镁会触发新骨形成的分子途径,并且镁可以提高磷酸钙骨移植材料在体内的性能。因此,本发明提供了最公知的骨形成环境和生物刺激。
根据本发明,除了镁之外,其他促进骨形成的元素例如锶可以包括到可生物降解的镁合金中。
根据本发明,螺钉,特别是螺钉的表面可以富含抗生素剂或促进骨形成的生长因子。
根据本发明,螺钉的螺纹可以形成到顶端中,以允许在插入过程中调节远端的水平来匹配牙槽嵴的高度。牙科设备的螺钉的螺纹用于以自攻(self-tapping)或预攻(pre-tapping)方式牢固固定在牙槽窝内。螺纹优选地仅设置在螺钉的锥形顶端,因为螺钉优选地具有比牙槽窝更小的宽度,从而为血液凝结物确保一些空间。
根据本发明,在螺钉的顶部形成平坦表面以充当用于单独的牙屏障膜的垫层。替代地,平坦表面可以形成为具有足够大的尺寸和形状以覆盖牙槽窝本身以充当屏障。平坦表面基本上等于或大于螺钉的外径以覆盖包括螺钉和牙槽窝之间的空间的整个牙槽窝。平坦表面可以具有不同的预定尺寸和形状,以覆盖分别对应于不同牙槽窝尺寸和形状的所有解剖学情况。在本文中,本领域技术人员公知的任何牙屏障膜均可与牙科设备一起使用。牙屏障膜可以通过牙槽窝周围的牙龈瓣进一步固定就位。类似地,螺钉的平坦表面可以被牙槽窝周围的牙龈瓣覆盖。
根据本发明,牙科设备是整体件,其中平坦表面和包括空腔和孔洞的螺钉由一种或多种可生物降解材料形成。牙科设备优选部分或全部通过增材制造方法制造,优选通过选择性激光熔化方法制造。
根据本发明,螺钉可以具有围绕空腔的均匀网格状结构、支架状结构或穿孔结构以形成孔洞。孔洞的大小应相对较小,以提高机械强度;然而,孔洞也必须足够大,以允许血液灌注到空腔中。在此,每个孔洞的尺寸优选为0.005至3毫米,更优选至少20微米,甚至更优选至少30微米,或者甚至更优选至少60微米,甚至更优选小于500微米。
根据本发明,螺钉可以在顶端具有开口,以允许血液从颌骨灌注到空腔中,而螺钉的远端,特别是平坦表面优选是封闭的,以防止软组织或杂质等侵入空腔中。
附图说明
在随后的描述中,将通过使用示例性实施例并参考附图更详细地描述本发明,其中
图1是根据本发明实施例的牙科设备已经插入其中的拔牙部位的示意性透视剖视图;
图2是根据本发明实施例的牙科设备的示意性剖视图。
附图中示出的附图标记表示如下所列的元件,并且将在示例性实施例的随后描述中参考。
1.牙科设备
2.牙槽窝
3.螺钉
4.颌骨
5.牙槽嵴
6.空腔
7.孔洞
8.螺纹
9.平坦表面
10.开口
11.牙龈瓣
具体实施方式
图1示出了根据本发明实施例的牙科设备(1),该牙科设备用于保留拔掉的牙齿的牙槽窝(2)周围的牙槽嵴,并且用于促进拔掉的牙齿的牙槽窝(2)内的颌骨再生。牙科设备(1)具有完全由可生物降解材料制成的螺钉(3)。螺钉(3)适于在牙槽窝(2)中的颌骨(4)内牢固固定。螺钉(3)的长度使其顶部在插入状态下与牙槽窝(2)周围的牙槽嵴(5)齐平。螺钉(3)具有空腔(6)和孔洞(7)以允许血液灌注到空腔中。孔洞(7)的直径优选基本上等于或大于20微米,更优选基本上等于或大于30微米,或者甚至更优选基本上等于或大于60微米。孔洞(7)的直径优选基本上小于500微米。
在该实施例的替代版本(未示出)中,螺钉(3)具有不同的预定长度和直径以覆盖分别对应于不同的牙槽窝(2)的深度和尺寸的所有解剖学情况。
可生物降解材料优选基于聚合物和/或基于金属。可生物降解材料优选包括镁和/或锶。可生物降解材料还可包括在螺钉(3)内或其表面上的生长因子和/或抗生素剂。螺钉(3)的不同部分可由具有不同成分和/或密度的可生物降解材料制成。
在该实施例中,螺钉(3)的螺纹(8)适于预攻。替代地,螺钉(3)的螺纹(8)可适于自攻。螺纹(8)优选仅设置在螺钉(3)的锥形顶端。
图2示出了图1的牙科设备(1)的剖视图。如图2所示,牙科设备(1)具有形成到螺钉(3)的顶部上的平坦表面(9),该平坦表面可以充当屏障本身或者用作牙屏障膜的支撑。平坦表面(9)等于或基本上大于螺钉(3)的外径以便覆盖整个牙槽窝(2)。牙屏障膜用于覆盖牙槽窝(2)。牙屏障膜与平坦表面(9)分开提供。平坦表面(9)具有适于支撑牙屏障膜的尺寸和形状,如垫层。
在该实施例的替代版本中,平坦表面(9)具有不同的预定尺寸和形状以覆盖分别对应于不同牙槽窝(2)的尺寸和形状的所有解剖学情况。
如图2所示,平坦表面(9)和包括空腔(6)和孔洞(7)的螺钉(3)提供为由可生物降解材料制成的整体件,优选由镁合金制成。牙科设备(1)优选部分或全部通过增材制造方法制造。增材制造方法优选包括应用于粉末形式的上述可生物降解材料的选择性激光熔化方法。在增材制造过程中通过可生物降解材料的选择性激光熔化形成具有优选直径或尺寸的孔洞(7)。
如图2所示,螺钉(3)具有围绕空腔(6)的穿孔结构。该穿孔结构在螺钉(3)中形成孔洞(7)以用于血液灌注。替代地,可以制造网格状或支架状结构以在螺钉(3)中形成孔洞(7)以用于血液灌注。
如图2所示,螺钉(3)在顶端具有开口(10),以允许血液从颌骨(4)灌注到空腔(6)中。并且螺钉(3)在远端封闭,以防止软组织和类似物侵入空腔(6)。
牙科设备(1)可在植入前用于新的拔牙部位。牙医确定牙槽窝(2)的深度、尺寸和形状,并选择长度、直径、尺寸和形状正确匹配的牙科设备(1)。此后,将螺钉(3)插入到牙槽窝(2)中,使得上端与牙槽嵴(5)处于同一水平。接下来,任选地将牙屏障膜放置在平坦表面(9)上并且通过周围牙龈中的牙龈瓣(11)固定就位。牙龈瓣(11)用缝线连接。当拔牙部位愈合时,牙科设备(1)被完全吸收,无需进行移除手术。此后,可以将种植体插入再生的颌骨中。利用本发明,可以显著降低植入失败率。
Claims (20)
1.一种用于保留拔掉的牙齿的牙槽窝(2)周围的牙槽嵴并促进拔掉的牙齿的牙槽窝(2)内的颌骨再生的牙科设备(1),其特征在于,所述牙科设备(1)包括:
螺钉(3),所述螺钉完全由可生物降解材料制成,以消除进行移除手术的需要,
其中所述螺钉(3)适于在所述牙槽窝(2)中的所述颌骨(4)内牢固固定,以防止骨组织再生期间的微运动,
其中所述螺钉(3)的长度使得其顶部在插入状态下与所述牙槽窝(2)周围的所述牙槽嵴(5)处于同一水平,以促进所述牙槽窝(2)内的完全骨再生,并且
其中所述螺钉(3)具有空腔(6)和孔洞(7),以允许血液灌注到所述空腔(6)中以用于形成血液凝结物,以充当所述牙槽窝(2)内的骨生长的生物基质,其中一个或多个所述孔洞(7)的直径都等于或大于20微米。
2.根据权利要求1所述的牙科设备(1),其特征在于,所述孔洞(7)的所述直径等于或大于30微米,或者等于或大于60微米。
3.根据权利要求1所述的牙科设备(1),其特征在于,所述孔洞(7)的所述直径小于500微米。
4.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,所述螺钉(3)的长度和/或直径设置有多个预定长度和/或直径中的任一者,以覆盖分别对应于不同牙槽窝(2)深度和尺寸的所有解剖学情况。
5.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,所述可生物降解材料是聚合物基和/或金属基的。
6.根据权利要求5所述的牙科设备(1),其特征在于,所述可生物降解材料包括镁。
7.根据权利要求5所述的牙科设备(1),其特征在于,所述可生物降解材料包括锶。
8.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,所述可生物降解材料包括生长因子和/或抗生素剂。
9.根据权利要求8所述的牙科设备(1),其特征在于,所述生长因子和/或所述抗生素剂沉积在所述螺钉(3)的表面上。
10.根据权利要求1所述的牙科设备(1),其特征在于,所述螺钉(3)的螺纹(8)适于自攻。
11.根据权利要求1所述的牙科设备(1),其特征在于,所述螺钉(3)的螺纹(8)适于预攻。
12.根据权利要求10或11所述的牙科设备(1),其特征在于,所述螺纹(8)仅设置在所述螺钉(3)的锥形顶端处。
13.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,还包括形成到所述螺钉(3)的顶部上的平坦表面(9),其中所述平坦表面(9)等于或大于所述螺钉(3)的外径,以覆盖所述牙槽窝(2)和所述螺钉(3)之间的空间。
14.根据权利要求13所述的牙科设备(1),其特征在于,还包括:用于覆盖所述牙槽窝(2)的牙屏障膜,其中所述平坦表面(9)具有适于从下方支撑所述牙屏障膜的尺寸和形状,其中所述牙屏障膜与所述平坦表面(9)分开提供。
15.根据权利要求13所述的牙科设备(1),其特征在于,所述平坦表面(9)具有不同预定尺寸和形状中的任一者,以覆盖分别对应于不同牙槽窝(2)尺寸和形状的所有解剖学情况。
16.根据权利要求13所述的牙科设备(1),其特征在于,所述平坦表面(9)和包括所述空腔(6)和所述孔洞(7)的所述螺钉(3)被提供为由所述可生物降解材料制成的整体件。
17.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,所述牙科设备(1)已经部分或全部通过增材制造方法制造。
18.根据权利要求17所述的牙科设备(1),其特征在于,所述增材制造方法包括选择性激光熔化方法。
19.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,所述螺钉(3)具有围绕所述空腔(6)的网格状、穿孔状和/或支架状结构。
20.根据权利要求1至3中任一项所述的牙科设备(1),其特征在于,所述螺钉(3)在顶端具有开口(10),以允许血液从所述颌骨(4)灌注到所述空腔(6)中,并且其中所述螺钉(3)在远端封闭,以防止软组织和类似物侵入所述空腔(6)。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19020081.6 | 2019-02-21 | ||
EP19020081.6A EP3698750A1 (en) | 2019-02-21 | 2019-02-21 | Dental device for ridge preservation and promotion of jaw bone regeneration in an extraction site |
PCT/EP2020/053914 WO2020169475A1 (en) | 2019-02-21 | 2020-02-14 | Dental device for ridge preservation and promotion of jaw bone regeneration in an extraction site |
Publications (2)
Publication Number | Publication Date |
---|---|
CN113473943A CN113473943A (zh) | 2021-10-01 |
CN113473943B true CN113473943B (zh) | 2023-09-29 |
Family
ID=65520038
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202080015625.9A Active CN113473943B (zh) | 2019-02-21 | 2020-02-14 | 用于在拔牙部位保留牙槽嵴和促进颌骨再生的牙科设备 |
Country Status (8)
Country | Link |
---|---|
US (1) | US20220151740A1 (zh) |
EP (2) | EP3698750A1 (zh) |
JP (1) | JP2022521304A (zh) |
KR (1) | KR20210128417A (zh) |
CN (1) | CN113473943B (zh) |
BR (1) | BR112021015550A2 (zh) |
CA (1) | CA3138474A1 (zh) |
WO (1) | WO2020169475A1 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20230122756A (ko) * | 2022-02-15 | 2023-08-22 | 주식회사 바이오템 | 3d 골유도 재생술용 본 스크류 |
US11872105B1 (en) * | 2022-12-01 | 2024-01-16 | Robert Parker | Dental implant device for regeneration of dental pulp and dentin |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4531916A (en) * | 1983-07-08 | 1985-07-30 | W. L. Gore & Associates, Inc. | Dental implant with expanded PTFE gingival interface |
DE19713305A1 (de) * | 1997-03-29 | 1998-10-01 | Wilfried Prof Dr Med D Engelke | Resorbierbarer Obturator |
CA2235705A1 (en) * | 1998-04-23 | 1999-10-23 | Douglas Alan Schappert | Integral guided tissue regeneration barrier for root-form dental implant |
US6325627B1 (en) * | 1999-10-20 | 2001-12-04 | Arthur Ashman | Method and apparatus for performing ridge preservation and implant treatment |
CN1351482A (zh) * | 2000-02-21 | 2002-05-29 | 张相健 | 牙槽嵴保护的方法和材料 |
AU2006336475A1 (en) * | 2006-01-13 | 2007-08-02 | Biodynamics, L.L.C. | Surgical fasteners and related implant devices having bioabsorbable components |
CN203458491U (zh) * | 2013-08-28 | 2014-03-05 | 章锦才 | 一种牙槽骨再生用的屏障膜的支撑固位螺钉组件 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL142933A0 (en) * | 2001-05-03 | 2002-04-21 | Dentis Technology Ltd | Polymeric dental implant and method for use thereof |
JP5507112B2 (ja) * | 2008-05-12 | 2014-05-28 | 旭化成ケミカルズ株式会社 | 高吸着性能多孔性成形体及びその製造方法 |
US20110111359A1 (en) * | 2009-11-09 | 2011-05-12 | Weathers Jr Arthur Kitchings | Dental extracted tooth replacement method |
WO2015106247A1 (en) * | 2014-01-13 | 2015-07-16 | Westover Brock B | Endosseous dental implant assembly |
DE102015102597A1 (de) | 2015-02-24 | 2016-08-25 | botiss biomaterials GmbH | Implantat zum Überdecken von Knochendefekten im Kieferbereich sowie Verfahren zu dessen Herstellung |
-
2019
- 2019-02-21 EP EP19020081.6A patent/EP3698750A1/en not_active Withdrawn
-
2020
- 2020-02-14 WO PCT/EP2020/053914 patent/WO2020169475A1/en unknown
- 2020-02-14 KR KR1020217027995A patent/KR20210128417A/ko unknown
- 2020-02-14 EP EP20704042.9A patent/EP3927277A1/en active Pending
- 2020-02-14 CN CN202080015625.9A patent/CN113473943B/zh active Active
- 2020-02-14 BR BR112021015550-3A patent/BR112021015550A2/pt unknown
- 2020-02-14 JP JP2021549326A patent/JP2022521304A/ja active Pending
- 2020-02-14 CA CA3138474A patent/CA3138474A1/en active Pending
- 2020-02-14 US US17/432,509 patent/US20220151740A1/en active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4531916A (en) * | 1983-07-08 | 1985-07-30 | W. L. Gore & Associates, Inc. | Dental implant with expanded PTFE gingival interface |
DE19713305A1 (de) * | 1997-03-29 | 1998-10-01 | Wilfried Prof Dr Med D Engelke | Resorbierbarer Obturator |
CA2235705A1 (en) * | 1998-04-23 | 1999-10-23 | Douglas Alan Schappert | Integral guided tissue regeneration barrier for root-form dental implant |
US6325627B1 (en) * | 1999-10-20 | 2001-12-04 | Arthur Ashman | Method and apparatus for performing ridge preservation and implant treatment |
CN1351482A (zh) * | 2000-02-21 | 2002-05-29 | 张相健 | 牙槽嵴保护的方法和材料 |
AU2006336475A1 (en) * | 2006-01-13 | 2007-08-02 | Biodynamics, L.L.C. | Surgical fasteners and related implant devices having bioabsorbable components |
CN203458491U (zh) * | 2013-08-28 | 2014-03-05 | 章锦才 | 一种牙槽骨再生用的屏障膜的支撑固位螺钉组件 |
Also Published As
Publication number | Publication date |
---|---|
KR20210128417A (ko) | 2021-10-26 |
US20220151740A1 (en) | 2022-05-19 |
EP3698750A1 (en) | 2020-08-26 |
EP3927277A1 (en) | 2021-12-29 |
BR112021015550A2 (pt) | 2021-10-05 |
JP2022521304A (ja) | 2022-04-06 |
CN113473943A (zh) | 2021-10-01 |
WO2020169475A1 (en) | 2020-08-27 |
CA3138474A1 (en) | 2020-08-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Artzi et al. | Bovine‐HA spongiosa blocks and immediate implant placement in sinus augmentation procedures: Histopathological and histomorphometric observations on different histological stainings in 10 consecutive patients | |
US8128402B2 (en) | Tubular bone anchoring element | |
US5700479A (en) | Surgical element and method for selective tissue regeneration | |
US9707058B2 (en) | Patient-specific implants with improved osseointegration | |
JP4245813B2 (ja) | 骨インプラント | |
US10517698B2 (en) | Dental implant wedges | |
US9757213B2 (en) | Hybrid dental implant | |
JP2015514496A (ja) | 歯科インプラント | |
CN113473943B (zh) | 用于在拔牙部位保留牙槽嵴和促进颌骨再生的牙科设备 | |
US20170014209A1 (en) | Periodontal Subperiosteal Tunnel Bone Graft Technique | |
CN109069230B (zh) | 一体化的混合牙植入体 | |
US20160128834A1 (en) | Scaffold implant system | |
US20220151745A1 (en) | Anatomical dental implant arranged to be implanted in a naturally occurring cavity of the jawbone | |
JPH11151253A (ja) | 義歯を人間の顎に保持するための歯科医術用上部構造のための顎インプラント | |
US20230210639A1 (en) | Dental support screw | |
RU48753U1 (ru) | Челюстной имплантат | |
KR200345611Y1 (ko) | 치과용 임플란트 | |
JPH0564646A (ja) | インプラントセツト | |
WO2023049526A2 (en) | Inner porous screw type implant | |
KR20230122756A (ko) | 3d 골유도 재생술용 본 스크류 | |
JP2004290418A (ja) | 歯槽骨・顎骨用部材 | |
Al-Rawee et al. | Influence of Extraction Socket Class on Success of Post Extraction Implant: A Clinical Study. | |
Benetti et al. | GUIDED TISSUE REGENERATION IN MAXILLOFACIAL SURGERY | |
WO2009118725A1 (en) | Tooth socket covering | |
JP2010063853A (ja) | 歯科用インプラント |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant |