CN113456778A - Composition for improving energy and preparation method thereof - Google Patents

Composition for improving energy and preparation method thereof Download PDF

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Publication number
CN113456778A
CN113456778A CN202110910351.6A CN202110910351A CN113456778A CN 113456778 A CN113456778 A CN 113456778A CN 202110910351 A CN202110910351 A CN 202110910351A CN 113456778 A CN113456778 A CN 113456778A
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parts
ginseng
effects
composition
galangal
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郑涵
杨继广
席宾
李朝阳
刘春颖
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Flower Of Life Beijing Health Management Co ltd
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Flower Of Life Beijing Health Management Co ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/64—Orobanchaceae (Broom-rape family)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/076—Poria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/40—Cornaceae (Dogwood family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9064—Amomum, e.g. round cardamom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Abstract

The invention belongs to the technical field of Chinese herbal medicines, and discloses a composition for improving energy and a preparation method thereof. The composition takes the cistanche as a monarch drug, and has the effects of tonifying kidney and supporting yang, and moistening intestines and promoting fluid production; the lucid ganoderma has the effects of tonifying qi, soothing the nerves, purifying blood and protecting liver function; corni fructus has effects of tonifying liver and kidney, astringing, and strengthening body constitution; angelica sinensis has the effects of enriching blood, regulating menstruation, protecting kidney and resisting oxidation; the ginseng is a ministerial drug which has the effects of warming the nature and entering the liver channel, tonifying the kidney and strengthening yang, enriching the blood and lifting qi; the sea-buckthorn is used for improving the immunity; fructus Amomi warms the middle-jiao and promotes qi circulation; galangal can dispel cold and relieve pain, and the whole formula is introduced; the tuckahoe and the black sesame have the functions of strengthening spleen and calming heart, tonifying essence and blood, being rich in a large amount of amino acids and various vitamins and promoting the absorption capacity of nutrient components. The preparation method comprises mixing vegetable oil with Chinese medicinal materials at short-time heating temperature, pulverizing all the materialsThen the mixture is blended into the oil solution again, the drug effect of the finished product is ensured, no toxic or side effect is caused, and the finished product meets the condition that the content of the effective components is lower than that of mouse gavage LD50And (4) standard amount.

Description

Composition for improving energy and preparation method thereof
Technical Field
The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a composition for improving energy and a preparation method thereof.
Background
Modern people need to be energetic at any time to solve a plurality of things in work and life due to high working pressure and high living pressure. However, as the rhythm accelerates, various problems occur in the human body.
The most common phenomenon in the existing life is energy reduction caused by kidney deficiency. Kidney deficiency refers to the deficiency of kidney essence, qi, yin and yang. There are many kinds of kidney deficiency, and the most common of them is kidney yin deficiency and kidney yang deficiency. Symptoms of kidney deficiency: the symptoms of kidney-yang deficiency include soreness of waist, cold limbs, intolerance of cold, even edema, cold symptoms, and poor sexual function which can also cause kidney-yang deficiency; the symptom of kidney yin deficiency is "heat", and mainly includes soreness of waist, dryness-heat, night sweat, sweating due to debility, dizziness, tinnitus, etc. Modern science proves that when people suffer from kidney deficiency, the immunity of people is reduced no matter the kidney is yin deficient or the kidney is yang deficient, and more evidence shows that when the kidney deficiency occurs, the immunity of the kidney is reduced, the microcirculation system of the kidney is also blocked, and the kidney collaterals are blocked. Therefore, the treatment of kidney deficiency should be combined with prevention and treatment.
The symptoms of kidney deficiency manifest themselves mentally as: memory decline, hypomnesis, inattention, lack of energy, and reduced work efficiency. The symptoms of kidney deficiency are emotionally manifested as: poor mood is often difficult to control, dizziness, irritability, anxiety, depression, and the like. Symptoms of kidney deficiency are expressed in the mind: lack of confidence, no enthusiasm for work, no enthusiasm for life, no goal and no direction.
At present, a lot of medicines or health care products for tonifying the kidney and improving energy are available on the market, but the effect of most medicines is not good, the side effect of most medicines is more, the harm to the health of human bodies can be caused, and the health care products have certain effect, but the health care products are high in price and are not enough in absorption rate for users.
Disclosure of Invention
In order to solve the above problems in the prior art, the present invention aims to provide a composition for increasing energy and a preparation method thereof.
The technical scheme adopted by the invention is as follows: the composition for improving energy is mainly prepared from the following raw materials in parts by mass:
10-15 parts of cistanche, 6-12 parts of lucid ganoderma, 5-10 parts of dogwood, 6-12 parts of angelica sinensis, 3-10 parts of ginseng, 3-9 parts of sea buckthorn, 3-6 parts of fructus amomi, 3-6 parts of galangal, 10-15 parts of poria cocos and 9-15 parts of black sesame.
Cistanche deserticola, name of traditional Chinese medicine. Is fleshy stem with scaly leaf of Cistanchis herba Y.C.Ma of Cistanche of Orobanchaceae. Has the effects of tonifying kidney, supporting yang, moistening intestine and relaxing bowels. Can be used for treating kidney yang deficiency, essence and blood deficiency, sexual impotence, premature ejaculation, infertility due to cold womb, soreness of waist and knees, asthenia, intestinal dryness, and constipation. Sweet, salty and warm in nature; it enters kidney and large intestine meridians.
Ganoderma lucidum and Chinese medicine name. Is dried fruiting body of Ganoderma lucidum (Leys. ex Fr.) Karst or Ganoderma sinense Zhao, Xu et Zhang of Ganoderma of Polyporaceae. Has effects of invigorating qi, tranquilizing mind, relieving cough and asthma. It can be used for treating restlessness of heart-mind, insomnia, palpitation due to fright, cough, asthma, excessive phlegm, and asthenia. Sweet in taste and neutral in nature; it enters heart, lung, liver and kidney meridians. The chemical composition contains polysaccharide, nucleoside, furan, sterol, alkaloid, triterpenes, oil, amino acids, proteins, enzymes, organic germanium, trace elements, etc. The pharmacological action of the ganoderma lucidum polysaccharide has the functions of regulating immunity, reducing blood sugar, reducing blood fat, resisting oxidation, resisting aging and resisting tumors; the triterpenes can purify blood and protect liver function; the Ganoderma preparation has tranquilizing, anticonvulsive, heart tonifying, arrhythmia relieving, blood pressure lowering, cough relieving, and asthma relieving effects; in addition, Ganoderma has anticoagulant, platelet aggregation inhibiting and antiallergic effects. Ganoderma lucidum has less toxicity due to toxicity, and Ganoderma lucidum percolate LD is injected into abdominal cavity of mouse5038.3 + -1.04 g/kg, and is prepared by intraperitoneal injection of hot alcohol extract of Ganoderma lucidum, and mouse LD506.75g/kg, the intragastric MLD is 165g/kg, the toxicity of the cold alcohol extract is lower, the rats are intragastric for 1.2g/kg and 12g/kg every day for 30 days, and the toxicity on growth and development, liver function, electrocardiogram and the like is avoided.
Cornus officinalis, the name of traditional Chinese medicine. Is dried mature pulp of Cornus officinalis Sieb.et Zucc. Has effects of invigorating liver and kidney, astringing and inducing astringency. Can be used for treating soreness of waist and knees, dizziness, tinnitus, sexual impotence, spermatorrhea, enuresis, frequent micturition, metrorrhagia, menorrhagia, profuse sweating, and asthenia. Sour and astringent taste, slightly warm nature; it enters liver and kidney meridians. Chemical components: the fruit contains cornin, ursolic acid, morroniside, 7-0-methyl morroniside, swertiamarin, and loganin. In addition, gallic acid, malic acid, tartaric acid, provitamin A, saponin, tannin, etc. can be added. The pharmacological action is as follows: 1. the function of resisting pathogenic microorganisms: the Corni fructus decoction can inhibit growth of Staphylococcus aureus in vitro, sour liquid obtained from fresh fruit pulp has inhibitory effect on typhoid fever and dysentery bacteria, and water infusion has inhibitory effect on Trichophyton violaceum in test tube to different degrees. 2. Impact on the immune system: the dogwood with different dosages can obviously increase the content of IgG in the serum of mice. And shows a significant inhibitory effect on contact dermatitis caused by DNCB. 3. Effects on substance metabolism: corni fructus has obvious effect in resisting adrenergic hyperglycemia, and can increase liver glycogen. Ursolic acid separated from fructus Corni ether extract can significantly reduce blood sugar and urine sugar. 4. Effects on the cardiovascular system: animal experiments prove that the dogwood can cause the blood pressure of shock animals to rise and the amplitude of heart beat waves to be increased, and has the antishock effect. 5. Effects on the blood system: the dogwood can reduce the specific viscosity of whole blood of a rat with hyperglycemia. And can inhibit platelet aggregation. 6. In addition, cornus officinalis has certain diuretic, anti-inflammatory, anticancer, antioxidant and anti-aging effects. And (3) toxicological effects: has low toxicity and can cause mild hyperemia on rabbit gastric mucosa.
Chinese angelica root, named as Chinese medicine. Is root of Angelica sinensis (Oliv) Diels. of Angelica of Umbelliferae. Has effects of replenishing blood, regulating menstruation, promoting blood circulation, relieving pain, and loosening bowel to relieve constipation. It can be used for treating blood deficiency, sallow complexion, menoxenia, amenorrhea, dysmenorrhea, blood deficiency, blood stagnation, pain due to blood cold, traumatic injury, rheumatalgia, superficial infection, pyocutaneous disease, intestinal dryness, and constipation. Sweet and pungent in flavor and warm in nature; it enters liver, heart and spleen meridians. Chemical components: the angelica contains neutral compounds such as beta-pinene, alpha-pinene, camphene and the likeAn oil component. Contains acidic oil components such as p-methylbenzyl alcohol and 5-methoxy-2, 3-xylenol, organic acid, saccharide, vitamins, amino acids, etc. The pharmacological action is as follows: 1. effects on the reproductive system: angelica sinensis has the function of regulating uterine smooth muscle in two directions. Mainly plays a role in inhibiting the isolated uterus and has a role in stimulating the in vivo uterus. 2. Effects on the cardiovascular system: the radix Angelicae sinensis fluid extract has effect in resisting myocardial ischemia, and radix Angelicae sinensis neutral oil also has protective effect on myocardial ischemia. It also has antiarrhythmic effect. The radix Angelicae sinensis extract has effects of dilating coronary artery and increasing coronary blood flow. 3. Effects on the blood system: the radix Angelicae sinensis powder has effects of reducing blood lipid and protecting arteriosclerosis aorta pathological changes. Ligustilide in radix Angelicae sinensis extract has platelet aggregation inhibiting effect. The angelica and the ferulic acid thereof have obvious antithrombotic effect. Angelica polysaccharide has the function of promoting hematopoiesis. 4. Impact on the immune system: the total acid of radix Angelicae sinensis has effects of improving cellular immunity and promoting humoral immunity. Angelica polysaccharide also has immunity enhancing effect. 5. Effects on the central nervous system: the effective component ligustilide in angelica has the function of inhibiting the central nervous system, and angelica has the analgesic function which is stronger than aminopyrine, the acute toxicity is extremely low 6, and the function of resisting pathogenic microorganisms is as follows: the angelica has antibacterial effects on in vitro dysentery, typhoid, paratyphoid, escherichia coli, diphtheria bacillus, vibrio cholerae, alpha and beta hemolytic streptococcus and the like; 7. impact on the respiratory system: the radix Angelicae sinensis component ligustilide has antiasthmatic effect. 8. In addition, radix Angelicae sinensis has effects of protecting liver, resisting tumor, resisting radiation, resisting inflammation, protecting kidney, resisting oxidation, and correcting protein metabolism disorder. And (3) toxicological effects: the toxicity of angelica is low, and LD of angelica is injected into mice by vein5080-100 g/kg; subcutaneous injection and intragastric administration of volatile oil LD50298mg/kg and 96mg/kg respectively; lD of ligustilide abdominal cavity injection50520 mg/kg; sodium ferulate intravenous injection and intragastric LD501.7g/kg and 3.6g/kg, respectively. The dog has intravenous injection of 2g/kg of angelica for 14 days continuously, and has no obvious effect on liver, kidney, electrocardiogram and hemogram. Feeding mice with 5% of radix Angelicae sinensis diet, and after 3-5 months, the animals grow strongly and the liver can oxidize glutamic acidThe force is significantly improved.
Ginseng, name of Chinese medicine. Is root of Panax ginseng C.A.Mey. belonging to Panax of Araliaceae. Has effects of invigorating primordial qi, invigorating spleen, benefiting lung, promoting fluid production, tranquilizing mind, and improving intelligence. It can be used for treating qi deficiency, hypolipemic, spleen qi deficiency, middle-jiao sinking, lung deficiency, asthma, cough, short breath, asthenia, thirst due to body fluid consumption, asthenia heat, diabetes, insomnia, amnesia, palpitation, blood deficiency, sallow complexion, sexual impotence, and cold womb. Sweet and slightly bitter in taste, slightly warm in nature; it enters lung, spleen and heart meridians. Chemical components: the product contains various ginsenosides, volatile oil, amino acids, trace elements, organic acids, saccharides, vitamins, etc. The pharmacological action is as follows: 1. effects on the nervous system: ginseng regulates the balance of excitatory and inhibitory processes in the central nervous system, and is manifested by small dose excitatory and large dose inhibitory effects on the central nervous system. 2. Improving brain tissue metabolism: ginseng can improve the excitation process and the inhibition process of brain, and restore the balance of the two processes. The ginsenoside Rb and Rg has protective effect on nerve tissue, and can promote the growth of nerve tissue and the establishment of nerve network. 3. Effects on memory acquisition disorders: the ginseng has bipolar and composition-dependent effects on learning and memory. 4. Effects on the pituitary-adrenal cortex system: ginseng has the effect of promoting the function of pituitary-adrenal cortex system. 5. Effects on the cardiovascular system: ginseng has the effects of exciting and inhibiting a plurality of animal hearts, exciting a small amount and inhibiting a large amount. The ginseng can increase the pressure with small dose and reduce the pressure with large dose. Ginsenoside has effects in resisting arrhythmia, protecting myocardium, reducing blood lipid, resisting arteriosclerosis, and dilating blood vessel. 6. The function of regulating the immune function: the ginsenoside can promote phagocytic function of reticuloendothelial system and increase concentration of nonspecific antibody in mouse serum. 7. Effects on the blood system: ginseng radix or its extract has effects of stimulating and protecting hematopoietic function of bone marrow, and enhancing hematopoietic function. Ginsenoside has effect in inhibiting platelet aggregation. 8. The antibacterial effect is as follows: the concentrated solution of Ginseng radix has inhibitory effect on bacteria la type shigella flexneri, beta type hemolytic streptococcus, and Penicillium purpurogenum. Higher concentration of staphylococcus aureus and Escherichia coli Anthrax bacteria, pneumococcus, Aspergillus niger, and Penicillium chrysogenum. 9. In addition, ginseng has certain functions of promoting gonadal function, promoting protein synthesis, resisting tumor, oxidation, aging, liver injury, gastric ulcer, fatigue, stress, radiation, mutation, hemostasis and the like. And (3) toxicological effects: pharmacological research shows that the ginseng and the active ingredients have low toxicity, and animal experiments can tolerate high dosage. Ginseng root powder mouse intragastric administration LD50More than 5 g/kg. Ginseng extract mouse subcutaneous injection administered LD50It was 16.5 mg/kg. Ginseng radix extract or ginsenoside for intraperitoneal injection LD50Between 300-700 mg/kg. LD of ginsenoside monomer for mouse intraperitoneal injection50Respectively as follows: rb 11110 mg/kg, Rb 2305 mg/kg, Rc410mg/kg, Rd 325mg/kg, Re 465mg/kg, Rf 1340 mg/kg, Rg 11258 mg/kg, Ro > 1000 mg/kg. LD of ginseng polypeptide for mouse intravenous injection50It was 1.62 g/kg.
Sea buckthorn, the name of traditional Chinese medicine. Is dried mature fruit of Hippophae rhamnoides L. belonging to genus Hippophae of family Elaeagnaceae. Has the effects of invigorating spleen, promoting digestion, relieving cough, eliminating phlegm, promoting blood circulation and removing blood stasis. It is mainly indicated for spleen deficiency with poor appetite, cough with excessive phlegm and blood stasis. Sweet and sour in taste and warm in nature; it enters spleen, stomach and lung meridians. Chemical components: the product contains vitamins (C, VA, VE, VB1, VB2, VB12, VK) and folic acid; flavonoids and terpenoids; proteins and various amino acids; fats and fatty acids; a saccharide. In addition, the beverage also contains alkaloid, coumarin and acidic substances, and is rich in minerals and trace elements. The pharmacological action is as follows: the fructus Hippophae flavone has effects of improving myocardial microcirculation, reducing myocardial oxygen consumption, resisting angiosclerosis, and resisting inflammation; the oleum Hippophae and its fruit juice have antifatigue, blood lipid reducing, radioprotective, antiulcer, hepatoprotective, and immunity enhancing effects.
Amomum fruit, the name of traditional Chinese medicine. Is dried mature fruit of Amomum villosum lour, Var, Xanthioides T.L.Wu et Senjen or Amomum longiligulare T.L.Wu, Amomum villosum of Amomum of Zingiberaceae. Has effects of eliminating dampness, activating qi-flowing, warming spleen and stomach, relieving diarrhea, and preventing miscarriage. It can be used for treating qi stagnation of spleen and stomach, damp obstruction of middle warmer, deficiency cold of spleen and stomach, emesis, threatened abortion, and pernicious vomiting. Pungent taste and warm nature; it enters spleen, stomach and kidney meridians. Chemical components: the YANGCHUNSHA contains volatile oil, which contains dexcamphor, borneol, bornyl acetate, limonene, nerolidol, etc., and saponin. The foundry sand contains volatile oil, which contains camphor, terpene, etc. as main components. The pharmacological action is as follows: 1. effect on gastrointestinal smooth muscle: the fructus Amomi decoction has effects in strengthening stomach, promoting secretion of digestive juice, promoting intestinal tract movement, and removing pneumatosis in digestive tube. 2. Anti-platelet aggregation: the fructus amomi can obviously inhibit platelet aggregation of the rabbit caused by ADP, has obvious protective effect on the mouse acute death induced by arachidonic acid, and has obvious effect on resisting the mouse acute death induced by collagen and adrenalin. 3. Antiulcer effect: fructus amomi can obviously reduce gastric acid secretion of rats. 4. The analgesic effect is as follows: the acetic acid writhing experiment shows that the product has obvious analgesic effect and can obviously reduce the number of mouse antibody cells.
Galangal, name of traditional Chinese medicine. Is dried rhizome of Alpinia officinarum Hance of Alpinia of Zingiberaceae. Has effects in dispelling cold, relieving pain, warming middle warmer, and relieving vomit. It is mainly used for treating stomach cold pain, stomach cold emesis. Pungent taste and hot property; it enters spleen and stomach meridians. Chemical components: contains volatile oil 0.5-1.5%, and the main components of the oil are 1, 8-cineole, methyl cinnamate, eugenol, pinene, piper cubebene and pungent galangal. Contains galangin, kaempferide, kaempferol, quercetin, isorhamnetin, etc. The pharmacological action is as follows: the water extract of the product has analgesic and anti-inflammatory effects, and the ether extract has analgesic effect, both can resist formation of animal experimental gastric ulcer and diarrhea caused by oleum ricini, and can prolong the mouth opening action duration of decapitated mice and the survival time of potassium cyanide poisoned mice; the decoction can increase the total acid output of gastric juice of dogs, excite the in vitro intestinal canal movement of rabbits, and resist the ink propulsion rate of mice after gastrointestinal inhibition caused by atropine; adopting in vivo thrombosis method, and administering rhizoma Alpiniae Officinarum water extract or volatile oil for intragastric administration to rat to achieve antithrombotic effect; the 100% decoction has effects in resisting gram-positive aerophiles such as Bacillus anthracis, alpha-or beta-hemolytic streptococcus, diphtheria and diphtheroid bacillus, pneumococcus, Staphylococcus aureus, and Staphylococcus albusAnd (4) performing bacterial action. And (3) toxicological effects: ether extract mouse gavage LD50The concentration of the soil is 0.4ml/kg, and the poisoning is characterized in that righting reflex disappears and the death lasts for more than 8 hours. The mice were drenched with 120g/kg of water extract and observed for 7 days without death. Galangal can mutate salmonella typhimurium TA98 and TA 100.
Tuckahoe, name of traditional Chinese medicine. Is dried sclerotium of Wolf of Poriacos (Schw.) of Polyporaceae family. Yun Ling is called Yun Ling in Yunnan province, and is superior in quality. Has effects of inducing diuresis to alleviate edema, eliminating dampness, invigorating spleen, and calming heart. It can be used for treating edema, phlegm retention, diarrhea due to spleen deficiency, palpitation, and insomnia. Sweet and light taste, mild in nature; it enters heart, lung and spleen meridians.
Black sesame, name of traditional Chinese medicine. Is black seed of Sesamum indicum L. of Sesamum of Pedaliaceae. Has the effects of tonifying essence and blood, moistening dryness and lubricating intestines. It can be used for treating premature gray hair, dizziness, dim eyesight, puerperal lactation deficiency, rheumatism, blood deficiency, constipation, etc. Sweet in taste and neutral in nature; it enters liver, kidney and large intestine meridians. Chemical components: the seed contains fatty oil, such as oleic acid, linoleic acid, palmitic acid, stearic acid, arachidic acid, tetracosanoic acid, glyceryl behenate, sesamin, sesamolin, sesamol, vitamin E, phytosterol, lecithin, folic acid, and further contains lipid ephedrine, protein, plantago sugar, sesamose, phosphorus, potassium, cytochrome, and calcium oxalate. The pharmacological action is as follows: 1. anti-aging effect: the black sesame seed can delay the aging phenomenon, reduce the lipofuscin level in the liver and testis, and increase the vitamin E content in the blood plasma. 2. Inhibition of adrenocortical function: the black sesame oil 0.2mg/100g can increase the content of vitamin C and cholesterol in adrenal gland, and the function of adrenal cortex is inhibited to some extent. 3. The hypoglycemic effect: semen Sesami Niger extract can reduce blood sugar, increase glycogen content and myoglycogen content, but reduce glycogen content in large dosage application. 4. The uterine stimulation effect: the water extract of semen Sesami Niger has effect in exciting uterus. 5. The anti-inflammatory effect is as follows: the fresh sterilized oleum Sesami can be applied to skin mucosa to relieve irritation and promote recovery of inflammation. 6. The function of reducing cholesterol: the linoleic acid contained in the product can reduce cholesterol content in blood. 7. In addition, the black sesame oil has the effects of increasing the blood cell volume, nourishing, relaxing bowels, inhibiting unsaturated fatty acid enzyme, and inhibiting unsaturated fatty acid enzyme by sesamin.
Preferably, the composition is mainly prepared from the following raw materials in parts by mass:
11-14 parts of cistanche, 7-10 parts of lucid ganoderma, 6-8 parts of dogwood, 7-10 parts of angelica, 4-8 parts of ginseng, 4-7 parts of sea buckthorn, 3.5-5 parts of fructus amomi, 3.5-5 parts of galangal, 11-14 parts of poria cocos and 10-14 parts of black sesame.
Preferably, the composition is mainly prepared from the following raw materials in parts by mass:
13 parts of cistanche, 8 parts of lucid ganoderma, 7 parts of dogwood, 8 parts of angelica, 6 parts of ginseng, 5 parts of sea-buckthorn, 4 parts of fructus amomi, 4 parts of galangal, 13 parts of poria cocos and 13 parts of black sesame.
A method for preparing a composition for improving energy comprises selecting radix Angelicae sinensis, Ginseng radix, fructus Hippophae, fructus Amomi, rhizoma Alpiniae Officinarum and semen Sesami Niger according to corresponding proportion, mixing, processing in a heated solvent, taking out radix Angelicae sinensis, Ginseng radix, fructus Hippophae, fructus Amomi, rhizoma Alpiniae Officinarum and semen Sesami Niger, mixing with Cistanchis herba, Ganoderma, Corni fructus and Poria, pulverizing, placing in the above processed solvent again, mixing, adding flavoring agent, and granulating to obtain the final product.
Preferably, the solvent is a vegetable oil.
Preferably, the mass ratio of the solvent to the total mass of the angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame is 3-6: 0.5-1.
Preferably, the heating temperature is 50-60 degrees celsius.
Preferably, the processing time is 3-4 minutes.
Preferably, the angelica, the ginseng, the sea buckthorn, the amomum villosum, the galangal and the black sesame are mixed and crushed with the cistanche, the ganoderma lucidum, the dogwood and the tuckahoe, and the grain diameter is 1200-2500 meshes;
the flavoring agent is honey;
the mass ratio of the flavoring agent to all the raw materials is 0.2-0.5: 1.
Preferably, the finished product is a pill.
The invention has the beneficial effects that:
the invention provides a composition for improving energy, which takes cistanche as a monarch drug, and has sweet, salty and warm properties; it has effects of invigorating kidney, tonifying yang, moistening intestine, and promoting fluid production; glossy ganoderma is sweet in taste and mild in nature; invigorating qi, tranquilizing mind, purifying blood, and protecting liver function; cornus officinalis is sour and astringent in taste and slightly warm in nature; enter liver and kidney meridians, tonify liver and kidney, astringe and astringe, strengthen body constitution; chinese angelica root, radix Angelicae sinensis is sweet and pungent in flavor and warm in nature; the Chinese medicinal composition has effects of tonifying blood, regulating menstruation, protecting kidney, and resisting oxidation; the ginseng is a ministerial drug which has the effects of warming the nature and entering the liver channel, tonifying the kidney and strengthening yang, enriching the blood and relieving qi; the sea-buckthorn is used for improving the immunity and resisting fatigue; fructus Amomi warms the middle-jiao and promotes qi circulation; galangal can dispel cold and relieve pain, and the whole formula is introduced; the tuckahoe and the black sesame have the effects of tonifying spleen and calming heart, tonifying essence and blood, improving strength, and simultaneously are rich in a large amount of amino acids and various vitamins and promote the absorption capacity of nutrient components.
The preparation method utilizes the temperature of the vegetable oil during short-time heating to mix with the Chinese herbal medicine raw materials, so that the effective components in the raw materials can be well fused with the oil agent, and the precipitation of the effective components and the content of the effective components in the product are improved. When all the raw materials are crushed and then are blended into the oil solution again, the use drug effect of the finished product is further ensured, no toxic or side effect is caused, and the finished product meets the condition that the content of effective components is lower than that of mouse gavage LD50And (4) standard amount.
Detailed Description
The present invention is further illustrated below with reference to specific examples. It will be appreciated by those skilled in the art that the following examples, which are set forth to illustrate the present invention, are intended to be part of the present invention, but not to be construed as limiting the scope of the present invention. The reagents used are all conventional products which are commercially available.
Example 1:
a preparation method of a composition for improving energy comprises the steps of selecting 6g of Chinese angelica, 3 g of ginseng, 3 g of sea buckthorn, 3 g of fructus amomi, 3 g of galangal and 9 g of black sesame according to a corresponding proportion, mixing the mixture in 162 g of vegetable oil heated to 50 ℃, processing for 4 minutes, fishing out the Chinese angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame after processing, mixing the mixture with 10g of cistanche, 6g of lucid ganoderma, 5g of dogwood and 10g of poria cocos, crushing the mixture, screening the mixture by a 1200-mesh sieve, placing the crushed mixture in the vegetable oil prepared for later use again, mixing the mixture evenly, adding 29 g of honey, and granulating to obtain a finished product.
Example 2:
a preparation method of a composition for improving energy comprises the steps of selecting 12g of Chinese angelica, 10g of ginseng, 9 g of sea buckthorn, 6g of fructus amomi, 6g of galangal and 15 g of black sesame according to a corresponding proportion, mixing the mixture in 348 g of vegetable oil heated to 60 ℃ to be processed for 3 minutes, fishing out the Chinese angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame after processing, mixing and crushing the mixture with 15 g of cistanche, 12g of lucid ganoderma, 10g of dogwood and 15 g of poria cocos, sieving the mixture with a 2500-mesh sieve, placing the mixture in the vegetable oil prepared for later use again, mixing the mixture evenly, adding 22 g of honey, and granulating to obtain a finished product.
Example 3:
a preparation method of a composition for improving energy comprises the steps of selecting 7g of Chinese angelica, 4g of ginseng, 4g of sea buckthorn, 3.5 g of fructus amomi, 3.5 g of galangal and 10g of black sesame according to corresponding proportions, mixing the mixture and placing the mixture in 192 g of vegetable oil heated to 50 ℃ for processing for 4 minutes, fishing out the Chinese angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame after the processing is finished, mixing the Chinese angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame with 11 g of cistanche, 7g of lucid ganoderma, 6g of dogwood and 11 g of poria cocos, crushing the mixture, screening the mixture by a 1200-mesh sieve, placing the crushed mixture in the vegetable oil for later use after the processing is finished again, mixing the mixture evenly, adding 13.5 g of honey, and granulating the mixture to obtain a finished product.
Example 4:
a preparation method of a composition for improving energy comprises the steps of selecting 10g of Chinese angelica, 8 g of ginseng, 7g of sea buckthorn, 5.5 g of fructus amomi, 5g of galangal and 14 g of black sesame according to corresponding proportions, mixing the mixture and putting the mixture into 297 g of vegetable oil heated to 60 ℃ for processing for 3 minutes, fishing out the Chinese angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame after processing, 14 g of cistanche, 10g of lucid ganoderma, 8 g of dogwood and 14 g of poria cocos, mixing and crushing the mixture, sieving the mixture by a 2500-mesh sieve, putting the mixture into the vegetable oil prepared for later use again, mixing the mixture evenly, adding 19.1 g of honey, and granulating to obtain a finished product
Example 5:
a preparation method of a composition for improving energy comprises the steps of selecting 8 g of Chinese angelica, 6g of ginseng, 5g of sea buckthorn, 4g of fructus amomi, 4g of galangal and 13 g of black sesame according to a corresponding proportion, mixing the mixture in 240 g of vegetable oil heated to 50 ℃, processing the mixture for 4 minutes, fishing out the Chinese angelica, the ginseng, the sea buckthorn, the fructus amomi, the galangal and the black sesame after processing, mixing the mixture with 13 g of cistanche, 8 g of lucid ganoderma, 7g of dogwood and 13 g of poria cocos, crushing the mixture, screening the mixture by a 2500-mesh screen, placing the mixture in the vegetable oil prepared for later use again, mixing the mixture evenly, adding 16.2 g of honey, and granulating to obtain a finished product.
The administration mode is as follows: the final product is honeyed pill granule, each granule is 1g, and is orally administered, wherein oral endocrine enzyme is used for gradually decomposing and absorbing components in the medicine, and daily dose is not more than 10 g.
The present invention is not limited to the above alternative embodiments, and any other products in various forms can be obtained by the present invention, and the present invention is within the protection scope of the present invention. The above embodiments should not be construed as limiting the scope of the present invention, and it will be understood by those skilled in the art that modifications may be made to the technical solutions described in the above embodiments, or equivalent substitutions may be made to some or all of the technical features thereof, without departing from the scope of the present invention, and at the same time, such modifications or substitutions may not make the essence of the corresponding technical solutions depart from the scope of the embodiments of the present invention.

Claims (10)

1. The composition for improving the energy is characterized by being prepared from the following raw materials in parts by mass:
10-15 parts of cistanche, 6-12 parts of lucid ganoderma, 5-10 parts of dogwood, 6-12 parts of angelica sinensis, 3-10 parts of ginseng, 3-9 parts of sea buckthorn, 3-6 parts of fructus amomi, 3-6 parts of galangal, 10-15 parts of poria cocos and 9-15 parts of black sesame.
2. The composition for improving energy as claimed in claim 1, wherein the composition is prepared from the following raw materials in parts by mass:
11-14 parts of cistanche, 7-10 parts of lucid ganoderma, 6-8 parts of dogwood, 7-10 parts of angelica, 4-8 parts of ginseng, 4-7 parts of sea buckthorn, 3.5-5 parts of fructus amomi, 3.5-5 parts of galangal, 11-14 parts of poria cocos and 10-14 parts of black sesame.
3. The composition for improving energy as claimed in claim 2, wherein the composition is prepared from the following raw materials in parts by mass:
13 parts of cistanche, 8 parts of lucid ganoderma, 7 parts of dogwood, 8 parts of angelica, 6 parts of ginseng, 5 parts of sea-buckthorn, 4 parts of fructus amomi, 4 parts of galangal, 13 parts of poria cocos and 13 parts of black sesame.
4. A method for preparing the composition for increasing energy according to any one of claims 1 to 3, wherein the method comprises selecting angelica sinensis, ginseng, sea buckthorn, amomum villosum, galangal and black sesame according to corresponding proportions, mixing and processing the mixture in a heated solvent, fishing out the angelica sinensis, the ginseng, the sea buckthorn, the amomum villosum, the galangal and the black sesame after processing, mixing and crushing the mixture with the cistanche, the ganoderma lucidum, the dogwood and the poria cocos, placing the mixture in the solvent prepared after processing, mixing the mixture uniformly, adding a flavoring agent, and granulating the mixture to obtain a finished product.
5. The method of claim 4, wherein the solvent is a vegetable oil.
6. The method for preparing the composition for improving energy according to claim 5, wherein the mass ratio of the solvent to the total mass of the angelica sinensis, the ginseng, the sea buckthorn, the amomum villosum, the galangal and the black sesame is 3-6: 0.5-1.
7. The method of claim 4, wherein the heating temperature is 50-60 degrees Celsius.
8. The method of claim 4, wherein the processing time is 3-4 minutes.
9. The method as claimed in claim 4, wherein the angelica, ginseng, hippophae rhamnoides, amomum villosum, galangal and black sesame are mixed with cistanche, ganoderma lucidum, dogwood and poria cocos and crushed to have a particle size of 1200-2500 meshes;
the flavoring agent is honey;
the mass ratio of the flavoring agent to all the raw materials is 0.2-0.5: 1.
10. The method of claim 4, wherein the finished product is a pill.
CN202110910351.6A 2021-08-09 2021-08-09 Composition for improving energy and preparation method thereof Pending CN113456778A (en)

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CN106615477A (en) * 2017-01-22 2017-05-10 新乡市人分九种健康管理有限公司 Compound substitutional tea with functions of warming kidney and tonifying qi, and preparation method of compound substitute tea
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CN101164565A (en) * 2006-10-18 2008-04-23 武彪 Quick-effective traditional Chinese medicine for treating beard and hair small and white, early white and alopecia in aged, and preparation method
CN107050182A (en) * 2017-01-15 2017-08-18 崔悦 The positive male balls of Bai Erxian
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