CN113456560A - Hair growth essence - Google Patents
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- CN113456560A CN113456560A CN202110771741.XA CN202110771741A CN113456560A CN 113456560 A CN113456560 A CN 113456560A CN 202110771741 A CN202110771741 A CN 202110771741A CN 113456560 A CN113456560 A CN 113456560A
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K8/9761—Cupressaceae [Cypress family], e.g. juniper or cypress
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61Q5/00—Preparations for care of the hair
- A61Q5/002—Preparations for repairing the hair, e.g. hair cure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention belongs to the field of daily chemicals. The hair growth and nourishing essence comprises the following components in percentage by mass: 0.1-0.5% of cacumen biotae extract, 0.1-0.5% of ginseng extract, 0.1-0.5% of hyaluronic acid, 0.1-1% of ginger extract, 0.1-1% of cordyceps militaris extract, 0.1-1% of astragalus membranaceus root extract, 0.1-2% of saccharide isomer and the balance of water. The hair nourishing cream has the advantages of mild and non-irritant essence, high transdermal absorption rate, controllable oil convergence, water supplementing and moisture preserving, scalp nourishing, hair root strengthening, bacteriostasis and inflammation diminishing, skin water and oil balance regulating, scalp environment stable state maintaining, hair growing cell proliferation and differentiation activating, hair follicle structure repairing, skin barrier rebuilding, effective hair strengthening and hair nourishing, hair nourishing and hair growing, hair loss and hair breakage reducing, quick response and short treatment course.
Description
Technical Field
The invention belongs to the field of daily chemicals, and particularly relates to a hair growing and nourishing essence.
Background
Alopecia is mainly classified into seborrheic alopecia, alopecia areata, anagen alopecia and telogen alopecia. Of these several common hair loss types, seborrheic alopecia is most common. Seborrheic alopecia is also called male alopecia and androgenetic alopecia, is the most common alopecia at present, is mainly characterized in that scalp grease is exuberant in secretion, hair is abnormal and greasy, hair follicle blockage and atrophy and degeneration are caused, most of the alopecia is long-term chronic alopecia, the cause of the seborrheic alopecia is not completely clear, and the alopecia can be related to factors such as immunity, heredity, hormone, local inflammatory response, nerves, environment and the like.
At present, the chemical synthesis medicine can be used for treating alopecia, has the characteristics of quick response, obvious effect and the like, but has the problem of large side effect, the medicine contains a large amount of hormone, hair is easy to fall off after regrowing and stopping the medicine, the dependence on the medicine is large, the effect is not lasting, and the alopecia is easy to repeat. The natural active hair-growing ingredients are applied to the field of hair loss prevention and hair growth, functional ingredients capable of effectively treating hair loss are screened from natural plants, the irritation of the medicine can be reduced, the transdermal absorption rate of a single plant extract is low, the effect is limited, and the treatment period is long; the hair loss phenomenon is more serious because the components in the plant extracts are complex and are not matched with each other, thus the biological toxicity is easy to generate and the scalp is stimulated. Therefore, the hair growth and hair nourishing essence which is mild, low in irritation and quick in effect is needed.
Disclosure of Invention
The invention aims to solve the technical problem of providing the hair growth and hair nourishing essence which is mild, non-irritant, high in transdermal absorption rate, capable of controlling oil convergence, moisturizing, nourishing scalp, strengthening hair roots, inhibiting bacteria, diminishing inflammation, regulating water and oil balance of skin, maintaining scalp environment steady state, activating proliferation and differentiation of hair growing cells, repairing hair follicle structures, reconstructing skin barriers, effectively fixing and nourishing hair, growing hair, reducing alopecia and hair breakage, quick in effect and short in treatment course.
The technical scheme of the invention is as follows:
the hair growth and nourishing essence comprises the following components in percentage by mass: 0.1-0.5% of cacumen biotae extract, 0.1-0.5% of ginseng extract, 0.1-0.5% of hyaluronic acid, 0.1-1% of ginger extract, 0.1-1% of cordyceps militaris extract, 0.1-1% of astragalus membranaceus root extract, 0.1-2% of saccharide isomer and the balance of water.
The effective components in the formula of the hair growth and nourishing essence have the following functions:
cacumen biotae extract: promoting blood circulation, enhancing metabolism of hair follicle, promoting hair regeneration, increasing superoxide dismutase activity, inhibiting inflammatory factor release, relieving inflammation, improving scalp ecological environment, astringing follicular orifice, preventing alopecia, and consolidating hair;
the ginseng extract: the hair growth promoting and hair growth promoting peptide is rich in small molecular biological peptide, can effectively achieve transdermal absorption rate, activate hair mother cells, promote blood circulation, accelerate hair mother cell division, activate and nourish dermal hair follicles, expand capillary vessels, grow hair, strengthen hair toughness, and reduce hair loss and hair breakage.
Hyaluronic acid: repairing hair scales, nourishing and strengthening hair, replenishing water and moisturizing for a long time, regulating water and oil balance of skin, inhibiting bacteria and diminishing inflammation, activating cell proliferation and differentiation, improving hair regeneration and hair follicle repair capacity, and growing and fixing hair;
ginger extract: promoting blood circulation, inhibiting bacteria, relieving inflammation, relieving itching, improving activity of germinal cells and environment of hair follicle, and promoting hair growth;
cordyceps militaris extract: promoting metabolism, activating cells, and promoting scalp absorption efficiency of effective components; stimulating the cell self-immunity ability, repairing the damaged cells, growing hair and growing hair; repairing scalp skin barrier, resisting oxidation, delaying aging, helping skin resist external environment and free radical damage, and reducing alopecia and hair breakage; bacteriostasis and inflammation, improving the micro-ecological environment of scalp and reducing alopecia and hair loss;
astragalus membranaceus root extract: promoting cell proliferation and differentiation, improving activity and content of hair follicle growth factor, delaying aging, activating cell autoimmune ability, repairing damaged cells, increasing number of hair follicles with complete structure, and promoting hair growth and hair growth;
saccharide isomerate: the long-acting moisturizing agent has the effects of moisturizing, improving the moisture content of scalp skin, enhancing cell water circulation, recovering skin elasticity, repairing damaged skin barrier, helping resist external stimulation, accelerating the generation of skin sebum membrane, and relieving the symptoms of dry scalp and itching.
Further, 0.2 to 0.5 percent of preservative and 0.1 to 1 percent of humectant.
Further, the preservative is phenoxyethanol.
Further, the humectant is at least one of an artemisia angustifolia leaf/stem extract, a pseudo-ginseng root extract, a saposhnikovia divaricata root extract, a folium artemisiae argyi extract and a cnidium monnieri seed extract.
The herba Artemisiae Annuae leaf/stem extract has antibacterial, water supplementing and moisture keeping effects. The Notoginseng radix extract contains various amino acids and proteins, has good permeability, and can remove excessive oil, promote blood circulation, and relieve and resist aging. The cnidium monnieri seed extract has antibacterial and anti-inflammatory effects, and is soothing and tranquilizing. The radix Saposhnikoviae extract has antibacterial, antiinflammatory, skin whitening, antioxidant, astringent, and oil controlling effects. The folium artemisiae argyi extract has the functions of diminishing inflammation, resisting allergy, resisting bacteria and repairing skin barriers. The plant extracts act on skin, and can diminish inflammation, inhibit bacteria, replenish water, moisturize, effectively remove redundant grease, inhibit grease secretion, regulate water and oil balance, repair skin barriers and maintain the stable environment of scalp skin.
The invention has the following beneficial effects:
according to the invention, multiple plant extracts are compounded, so that the synergistic effect is realized, the transdermal absorption efficiency is high, the bacteriostasis and the inflammation are realized, the scalp micro-ecology is improved, the blood circulation is promoted, the cell proliferation and differentiation are accelerated, the hair growing cells are activated, the hair follicle structure is repaired, the hair follicle density is improved, the hair regeneration is promoted, and the hair growing and hair restoring are realized; nourishing scalp, strengthening hair root, promoting hair growth and consolidating hair; improving cell autoimmunity, reconstructing scalp barrier, helping scalp and scalp resist external stimulation, and reducing alopecia and hair breakage. Hyaluronic acid, saccharide isomerous body and humectant are matched, so that long-acting water replenishing and moisture preserving effects can be achieved, cell water circulation is activated, transdermal absorption of effective components is promoted, water and oil balance of skin is adjusted, and scalp inflammation such as dryness, itching, scurf and the like is reduced; repairing hair scales, nourishing and strengthening hair, smoothing frizziness, reducing combing difficulty and reducing alopecia and broken hair; the scalp sebum membrane is repaired, the scalp is protected from being damaged, the removal difficulty of the effective components on the scalp is increased, the action time of the effective components on the scalp is prolonged, and the transdermal absorption amount of the effective components can be improved to a certain extent.
Detailed Description
The present invention will be described in detail with reference to examples, which are only preferred embodiments of the present invention and are not intended to limit the present invention.
Example 1
The hair growth and nourishing essence comprises the following components in percentage by mass: 0.1% of cacumen biotae extract, 0.5% of ginseng extract, 0.1% of hyaluronic acid, 0.8% of ginger extract, 0.8% of cordyceps militaris extract, 0.1% of astragalus membranaceus root extract, 2% of carbohydrate isomer, 0.2% of phenoxyethanol and the balance of water.
Example 2
The hair growth and nourishing essence comprises the following components in percentage by mass: 0.5% of cacumen biotae extract, 0.1% of ginseng extract, 0.5% of hyaluronic acid, 0.1% of ginger extract, 0.1% of cordyceps militaris extract, 1% of astragalus membranaceus root extract, 0.1% of saccharide isomer, 0.2% of phenoxyethanol, 0.5% of southernwood leaf/stem extract, 0.5% of cnidium monnieri seed extract and the balance of water.
Example 3
The hair growth and nourishing essence comprises the following components in percentage by mass: 0.3% of cacumen biotae extract, 0.3% of ginseng extract, 0.2% of hyaluronic acid, 0.5% of ginger extract, 0.6% of cordyceps militaris extract, 0.5% of astragalus membranaceus root extract, 1% of saccharide isomer, 0.2% of phenoxyethanol, 0.2% of southernwood leaf/stem extract, 0.2% of pseudo-ginseng root extract, 0.2% of radix sileris root extract, 0.2% of folium artemisiae argyi extract, 0.2% of cnidium monnieri seed extract and the balance of water.
Comparative example 1
The hair growth and nourishing essence comprises the following components in percentage by mass: 0.1% of cacumen biotae extract, 0.5% of ginseng extract, 0.8% of ginger extract, 0.8% of cordyceps militaris extract, 0.1% of astragalus membranaceus root extract, 2.1% of saccharide isomer, 0.2% of phenoxyethanol and the balance of water.
Comparative example 2
The hair growth and nourishing essence comprises the following components in percentage by mass: 0.5% of cacumen biotae extract, 1.1% of ginseng extract, 0.5% of hyaluronic acid, 0.1% of ginger extract, 0.1% of cordyceps militaris extract, 0.1% of saccharide isomer, 0.2% of phenoxyethanol, 0.5% of southernwood leaf/stem extract, 0.5% of cnidium monnieri seed extract and the balance of water.
Comparative example 3
The hair growth and nourishing essence comprises the following components in percentage by mass: 0.3% of cacumen biotae extract, 0.9% of ginseng extract, 0.2% of hyaluronic acid, 0.5% of ginger extract, 0.5% of astragalus membranaceus root extract, 1% of saccharide isomer, 0.2% of phenoxyethanol, 0.2% of southernwood leaf/stem extract, 0.2% of pseudo-ginseng root extract, 0.2% of radix sileris root extract, 0.2% of folium artemisiae argyi extract, 0.2% of cnidium monnieri seed extract and the balance of water.
First, blood circulation test
For 3 examples and 3 comparative examples of the hair growth and development essence of the present invention, the degree of blood circulation in the skin was measured using a Laser Doppler Perfusion Imager (LDPI). In a constant temperature and humidity room, the hair is washed by shampoo and then dried, the hair is adapted for 30 minutes, and an initial value is measured by LDPI. The blood flow rate before and after application of the sample was calculated by measuring the initial blood flow of the head of 60 volunteers with hair loss by LDPI, dividing the test subjects into 6 groups of 10 persons, applying the same amount of each of examples 1-3 and comparative examples 1-3 to the scalp, and measuring the blood flow again (the test period is one week, and the test period is once in the morning and night), and the test results are shown in the following table:
sample (I) | Rate of change of blood flow% |
Example 1 | 13.6 |
Example 2 | 14.8 |
Example 3 | 16.3 |
Comparative example 1 | 13.2 |
Comparative example 2 | 12.8 |
Comparative example 3 | 13.5 |
Therefore, the essence of the invention can promote blood circulation.
Second, hair growth and anti-hair loss effect test
The hair growth and hair loss prevention effects of 3 examples and 3 comparative examples of the hair growth and hair growth essence of the invention are tested: 120 alopecia volunteers were selected, and one month before the test was an elution period during which hair growth promoting drugs and glucocorticoids were not used. The test period was one month, the test subjects were divided into 6 groups of 20 persons, and the same amount of each of examples 1 to 3 and comparative examples 1 to 3 was applied to the scalp once in the morning and once in the evening. The effects of the examples and comparative examples were evaluated according to the following scoring criteria: preventing alopecia: the hair loss is stopped in the 5-point classification, and the hair loss is serious in the 0-point classification; ② hair growth rate: the 5 point is good hair growth, the 4 point is more than 70 percent hair regeneration, the 3 point is more than 50 percent hair regeneration, the 2 point is more than 30 percent hair regeneration, and the 1 point is less than 30 percent hair regeneration. The test results are given in the following table:
test items | Example 1 | Example 2 | Example 3 | Comparative example 1 | Comparative example 2 | Comparative example 3 |
Rate of falling off | 3.8 | 4.2 | 4.5 | 3.6 | 3.7 | 3.8 |
Rate of hair growth | 3.6 | 4.3 | 4.6 | 3.5 | 3.5 | 3.7 |
Therefore, the essence of the invention can promote hair growth and effectively reduce alopecia and hair loss.
The hair nourishing cream has the advantages of mild and non-irritant essence, high transdermal absorption rate, controllable oil convergence, water supplementing and moisture preserving, scalp nourishing, hair root strengthening, bacteriostasis and inflammation diminishing, skin water and oil balance regulating, scalp environment stable state maintaining, hair growing cell proliferation and differentiation activating, hair follicle structure repairing, skin barrier rebuilding, effective hair strengthening and hair nourishing, hair nourishing and hair growing, hair loss and hair breakage reducing, quick response and short treatment course.
Claims (4)
1. The essence for promoting hair growth is characterized by comprising the following components in percentage by mass: 0.1-0.5% of cacumen biotae extract, 0.1-0.5% of ginseng extract, 0.1-0.5% of hyaluronic acid, 0.1-1% of ginger extract, 0.1-1% of cordyceps militaris extract, 0.1-1% of astragalus membranaceus root extract, 0.1-2% of saccharide isomer and the balance of water.
2. The essence for promoting hair growth according to claim 1, further comprising 0.2 to 0.5% of a preservative and 0.1 to 1% of a humectant.
3. The hair growth and nourishing essence according to claim 2, wherein the preservative is phenoxyethanol.
4. The essence of claim 2, wherein the humectant is at least one of Artemisia angustifolia leaf/stem extract, Panax notoginseng root extract, Saposhnikovia divaricata root extract, Artemisia argyi leaf extract, and cnidium monnieri seed extract.
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CN202110771741.XA CN113456560A (en) | 2021-07-08 | 2021-07-08 | Hair growth essence |
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CN202110771741.XA CN113456560A (en) | 2021-07-08 | 2021-07-08 | Hair growth essence |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN115554380A (en) * | 2022-06-13 | 2023-01-03 | 浩溪(海南)生物科技有限公司 | Composition for preventing and treating alopecia by acting on hair follicle tissues and application thereof |
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2021
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN115554380A (en) * | 2022-06-13 | 2023-01-03 | 浩溪(海南)生物科技有限公司 | Composition for preventing and treating alopecia by acting on hair follicle tissues and application thereof |
CN115554380B (en) * | 2022-06-13 | 2023-09-26 | 浩溪(海南)生物科技有限公司 | Composition for preventing and treating alopecia by acting on hair follicle tissue and application thereof |
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Application publication date: 20211001 |