CN113425815A - 一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用 - Google Patents
一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用 Download PDFInfo
- Publication number
- CN113425815A CN113425815A CN202110928227.2A CN202110928227A CN113425815A CN 113425815 A CN113425815 A CN 113425815A CN 202110928227 A CN202110928227 A CN 202110928227A CN 113425815 A CN113425815 A CN 113425815A
- Authority
- CN
- China
- Prior art keywords
- preparation
- yeast
- powder
- root
- leaf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 58
- 239000003814 drug Substances 0.000 title claims abstract description 49
- 210000001596 intra-abdominal fat Anatomy 0.000 title claims abstract description 29
- 238000009825 accumulation Methods 0.000 title claims abstract description 19
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 52
- 239000000843 powder Substances 0.000 claims description 51
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims description 50
- 235000019991 rice wine Nutrition 0.000 claims description 32
- 241000205585 Aquilegia canadensis Species 0.000 claims description 30
- 241000218628 Ginkgo Species 0.000 claims description 30
- 235000011201 Ginkgo Nutrition 0.000 claims description 30
- 235000008100 Ginkgo biloba Nutrition 0.000 claims description 30
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 29
- 244000303040 Glycyrrhiza glabra Species 0.000 claims description 29
- 210000002345 respiratory system Anatomy 0.000 claims description 29
- 240000007594 Oryza sativa Species 0.000 claims description 28
- 235000007164 Oryza sativa Nutrition 0.000 claims description 28
- 235000009566 rice Nutrition 0.000 claims description 28
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims description 27
- 235000011477 liquorice Nutrition 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 23
- 239000006187 pill Substances 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 21
- 210000000582 semen Anatomy 0.000 claims description 17
- 235000014101 wine Nutrition 0.000 claims description 17
- 235000013312 flour Nutrition 0.000 claims description 16
- 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims description 15
- 235000003097 Artemisia absinthium Nutrition 0.000 claims description 15
- 240000001851 Artemisia dracunculus Species 0.000 claims description 15
- 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims description 15
- 235000003261 Artemisia vulgaris Nutrition 0.000 claims description 15
- 241000132012 Atractylodes Species 0.000 claims description 15
- 235000004415 Burchellia bubalina Nutrition 0.000 claims description 15
- 240000008537 Burchellia bubalina Species 0.000 claims description 15
- 235000007516 Chrysanthemum Nutrition 0.000 claims description 15
- 244000189548 Chrysanthemum x morifolium Species 0.000 claims description 15
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims description 15
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims description 15
- 235000009685 Crataegus X maligna Nutrition 0.000 claims description 15
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims description 15
- 235000009486 Crataegus bullatus Nutrition 0.000 claims description 15
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 15
- 235000009682 Crataegus limnophila Nutrition 0.000 claims description 15
- 240000000171 Crataegus monogyna Species 0.000 claims description 15
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 15
- 235000002313 Crataegus paludosa Nutrition 0.000 claims description 15
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims description 15
- 241001289529 Fallopia multiflora Species 0.000 claims description 15
- 235000003332 Ilex aquifolium Nutrition 0.000 claims description 15
- 235000002296 Ilex sandwicensis Nutrition 0.000 claims description 15
- 235000002294 Ilex volkensiana Nutrition 0.000 claims description 15
- 240000002853 Nelumbo nucifera Species 0.000 claims description 15
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims description 15
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims description 15
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims description 15
- 244000131316 Panax pseudoginseng Species 0.000 claims description 15
- 241001522129 Pinellia Species 0.000 claims description 15
- 240000004980 Rheum officinale Species 0.000 claims description 15
- 235000008081 Rheum officinale Nutrition 0.000 claims description 15
- 241000304195 Salvia miltiorrhiza Species 0.000 claims description 15
- 235000011135 Salvia miltiorrhiza Nutrition 0.000 claims description 15
- 241000219784 Sophora Species 0.000 claims description 15
- 241000205578 Thalictrum Species 0.000 claims description 15
- 244000269722 Thea sinensis Species 0.000 claims description 15
- 235000006468 Thea sinensis Nutrition 0.000 claims description 15
- 239000001138 artemisia absinthium Substances 0.000 claims description 15
- 235000020279 black tea Nutrition 0.000 claims description 15
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims description 15
- 240000005528 Arctium lappa Species 0.000 claims description 14
- 235000003130 Arctium lappa Nutrition 0.000 claims description 14
- 240000008564 Boehmeria nivea Species 0.000 claims description 14
- 244000077995 Coix lacryma jobi Species 0.000 claims description 14
- 240000003146 Lobelia chinensis Species 0.000 claims description 14
- 238000001914 filtration Methods 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 14
- 230000008569 process Effects 0.000 claims description 14
- 241000045403 Astragalus propinquus Species 0.000 claims description 13
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 13
- 235000006533 astragalus Nutrition 0.000 claims description 13
- 241000218671 Ephedra Species 0.000 claims description 12
- 238000001035 drying Methods 0.000 claims description 12
- 238000000227 grinding Methods 0.000 claims description 12
- 238000002156 mixing Methods 0.000 claims description 12
- 238000002791 soaking Methods 0.000 claims description 12
- 241000112528 Ligusticum striatum Species 0.000 claims description 11
- 235000006753 Platycodon grandiflorum Nutrition 0.000 claims description 11
- 240000003582 Platycodon grandiflorus Species 0.000 claims description 11
- 235000008708 Morus alba Nutrition 0.000 claims description 9
- 240000000249 Morus alba Species 0.000 claims description 9
- 235000006140 Raphanus sativus var sativus Nutrition 0.000 claims description 8
- 238000012258 culturing Methods 0.000 claims description 8
- 238000011049 filling Methods 0.000 claims description 8
- 238000007873 sieving Methods 0.000 claims description 8
- 244000080767 Areca catechu Species 0.000 claims description 7
- 244000037364 Cinnamomum aromaticum Species 0.000 claims description 7
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 claims description 7
- 241001523681 Dendrobium Species 0.000 claims description 7
- 244000046146 Pueraria lobata Species 0.000 claims description 7
- 235000010575 Pueraria lobata Nutrition 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 claims description 5
- 238000001816 cooling Methods 0.000 claims description 5
- 238000005520 cutting process Methods 0.000 claims description 5
- 235000017166 Bambusa arundinacea Nutrition 0.000 claims description 4
- 235000017491 Bambusa tulda Nutrition 0.000 claims description 4
- 241000244365 Ligusticum sinense Species 0.000 claims description 4
- 244000082204 Phyllostachys viridis Species 0.000 claims description 4
- 235000015334 Phyllostachys viridis Nutrition 0.000 claims description 4
- 239000011425 bamboo Substances 0.000 claims description 4
- 239000008187 granular material Substances 0.000 claims description 4
- 238000010298 pulverizing process Methods 0.000 claims description 4
- 238000005096 rolling process Methods 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
- 238000003756 stirring Methods 0.000 claims description 4
- 241001673966 Magnolia officinalis Species 0.000 claims description 3
- 235000006751 Platycodon Nutrition 0.000 claims description 3
- 244000274050 Platycodon grandiflorum Species 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 229930189914 platycodon Natural products 0.000 claims description 3
- 241000049624 Alisma plantago-aquatica subsp. orientale Species 0.000 claims description 2
- 241000213006 Angelica dahurica Species 0.000 claims description 2
- 235000008078 Arctium minus Nutrition 0.000 claims description 2
- 235000015221 Bupleurum rotundifolium Nutrition 0.000 claims description 2
- 244000236521 Bupleurum rotundifolium Species 0.000 claims description 2
- 241001465251 Ephedra sinica Species 0.000 claims description 2
- 241000893536 Epimedium Species 0.000 claims description 2
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 2
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 2
- 229940107666 astragalus root Drugs 0.000 claims description 2
- 238000005516 engineering process Methods 0.000 claims description 2
- 235000018905 epimedium Nutrition 0.000 claims description 2
- 229940010454 licorice Drugs 0.000 claims description 2
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 2
- 241001247821 Ziziphus Species 0.000 claims 6
- 244000088415 Raphanus sativus Species 0.000 claims 3
- 230000000694 effects Effects 0.000 abstract description 18
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract description 6
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract description 5
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract description 4
- 108010007622 LDL Lipoproteins Proteins 0.000 abstract description 4
- 102000007330 LDL Lipoproteins Human genes 0.000 abstract description 4
- 210000004072 lung Anatomy 0.000 abstract description 4
- 230000009467 reduction Effects 0.000 abstract description 4
- 208000004930 Fatty Liver Diseases 0.000 abstract description 3
- 206010019708 Hepatic steatosis Diseases 0.000 abstract description 3
- 208000010706 fatty liver disease Diseases 0.000 abstract description 3
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract description 3
- 208000024172 Cardiovascular disease Diseases 0.000 abstract description 2
- 206010013975 Dyspnoeas Diseases 0.000 abstract description 2
- 230000015556 catabolic process Effects 0.000 abstract description 2
- 208000026106 cerebrovascular disease Diseases 0.000 abstract description 2
- 230000002526 effect on cardiovascular system Effects 0.000 abstract description 2
- 238000001727 in vivo Methods 0.000 abstract description 2
- 210000000056 organ Anatomy 0.000 abstract description 2
- 208000000059 Dyspnea Diseases 0.000 abstract 1
- 238000001125 extrusion Methods 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 239000003925 fat Substances 0.000 description 42
- 210000004369 blood Anatomy 0.000 description 17
- 239000008280 blood Substances 0.000 description 17
- 240000008866 Ziziphus nummularia Species 0.000 description 8
- 241000220259 Raphanus Species 0.000 description 5
- 150000002632 lipids Chemical class 0.000 description 4
- 210000004185 liver Anatomy 0.000 description 4
- 210000004003 subcutaneous fat Anatomy 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 208000035150 Hypercholesterolemia Diseases 0.000 description 3
- 206010020772 Hypertension Diseases 0.000 description 3
- 208000008589 Obesity Diseases 0.000 description 3
- 206010041235 Snoring Diseases 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 208000006575 hypertriglyceridemia Diseases 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 229940126680 traditional chinese medicines Drugs 0.000 description 3
- 210000001835 viscera Anatomy 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 206010014486 Elevated triglycerides Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 235000008599 Poria cocos Nutrition 0.000 description 2
- 244000197580 Poria cocos Species 0.000 description 2
- 108010062497 VLDL Lipoproteins Proteins 0.000 description 2
- 210000000683 abdominal cavity Anatomy 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 235000005911 diet Nutrition 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 235000020824 obesity Nutrition 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 210000000813 small intestine Anatomy 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- XOJVHLIYNSOZOO-SWOBOCGESA-N Arctiin Chemical compound C1=C(OC)C(OC)=CC=C1C[C@@H]1[C@@H](CC=2C=C(OC)C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O3)O)=CC=2)C(=O)OC1 XOJVHLIYNSOZOO-SWOBOCGESA-N 0.000 description 1
- 206010003210 Arteriosclerosis Diseases 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- 206010006322 Breath holding Diseases 0.000 description 1
- 102000014914 Carrier Proteins Human genes 0.000 description 1
- 108010078791 Carrier Proteins Proteins 0.000 description 1
- 206010052895 Coronary artery insufficiency Diseases 0.000 description 1
- 240000004638 Dendrobium nobile Species 0.000 description 1
- 208000000563 Hyperlipoproteinemia Type II Diseases 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 241000736919 Pelodiscus sinensis Species 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 210000001789 adipocyte Anatomy 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 208000011775 arteriosclerosis disease Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000011976 chest X-ray Methods 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 201000009151 chronic rhinitis Diseases 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 230000000020 effect on hyperlipemia Effects 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 201000001386 familial hypercholesterolemia Diseases 0.000 description 1
- 201000005577 familial hyperlipidemia Diseases 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 210000000569 greater omentum Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 235000003642 hunger Nutrition 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 150000002596 lactones Chemical class 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000001087 myotubule Anatomy 0.000 description 1
- 235000003715 nutritional status Nutrition 0.000 description 1
- 230000037081 physical activity Effects 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 125000005457 triglyceride group Chemical group 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 239000013585 weight reducing agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/346—Platycodon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
- A61K36/605—Morus (mulberry)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
- A61K36/8888—Pinellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/02—Preparation of other alcoholic beverages by fermentation
- C12G3/021—Preparation of other alcoholic beverages by fermentation of botanical family Poaceae, e.g. wheat, millet, sorghum, barley, rye, or corn
- C12G3/022—Preparation of other alcoholic beverages by fermentation of botanical family Poaceae, e.g. wheat, millet, sorghum, barley, rye, or corn of botanical genus Oryza, e.g. rice
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/02—Preparation of other alcoholic beverages by fermentation
- C12G3/026—Preparation of other alcoholic beverages by fermentation with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides, added before or during the fermentation stage; with flavouring ingredients added before or during the fermentation stage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
- C12G3/05—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides
- C12G3/055—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with health-improving ingredients, e.g. flavonoids, flavones, polyphenols or polysaccharides extracted from plants
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Obesity (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
Abstract
本发明公开了一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用，针对长期内脏脂肪堆积导致的高血脂、心脑血管疾病、身体器官机能下降等并发症，以及肺部受到脂肪的挤压导致呼吸困难等问题，而创新研究的一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用，采用中药材配方及药曲制作治疗呼吸道的药酒和降脂减肥的药酒，也可采用口服液或蜜丸替代药酒。本发明对脂肪在体内分解代谢有促进作用，对脂肪肝、血清胆固醇增高、β脂蛋白增高、甘油三酯增高等疗效显著，以此达到治疗内脏脂肪堆积的目的。
Description
技术领域
本发明属于中药技术领域，具体而言，涉及一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用。
背景技术
人体脂肪含量常受营养状况和体力活动等因素的影响而有较大变动。多吃碳水化合物和脂肪其含量增加，饥饿则减少；当机体能量消耗较多而食物供应不足时体内脂肪就大量动员，经血循环运输到各组织，被氧化消耗。正常人体按照体重计算，所含脂类占14％-19％，胖人占约34％，过胖的人可高达60％，绝大部分是以甘油三酯的形式贮存于脂肪组织内，脂肪组织含脂肪细胞，多分布于腹腔、皮下和肌纤维间，故又称为可变脂。内脏脂肪是人体脂肪中的一种，它与皮下脂肪不同，它围绕着人的脏器，如大网膜、肠系膜、肝脏和肾脏等，主要存在于腹腔内。
内脏脂肪对于我们的健康意义重大。一定量的内脏脂肪其实是人体必需的，因为内脏脂肪围绕着人的脏器，对人的内脏起着支撑、稳定和保护的作用。但是内脏脂肪过多是身体代谢紊乱的表现，长期内脏脂肪堆积会导致高血脂、心脑血管疾病、身体器官机能下降等并发症，肺部受到脂肪的挤压，呼吸会变得困难，血液也难以进行有效的氧气循环，有可能损害免疫系统、引起高血压。现代社会很多内脏脂肪多的人表面看起来可能是体型肥胖，但也很有可能是体型偏瘦，特别是上班族和中老年，很多都需要给自己的内脏脂肪“减减肥”。科研发现，内脏脂肪和皮下脂肪存在并发的关系，内脏脂肪很容易引发皮下脂肪增多，这就是为什么很多肥胖人群通过减肥药剂等多种形式进行减肥，最后很容易反弹的根本原因，内脏脂肪不减，只减皮下脂肪相当于治标不治本，也是不健康的减肥方式。
发明内容
为了解决上述技术问题，本发明公开了一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用，本发明采用中药材配方及药曲制作治疗呼吸道的药酒和降脂减肥的药酒，也可采用口服液或蜜丸替代药酒，以此达到治疗内脏脂肪堆积的目的。
为了实现所述发明目的，本发明采用如下技术方案：
一种用于治疗内脏脂肪堆积的中药制剂，由治疗呼吸道的药酒和降脂减肥的药酒组成，所述治疗呼吸道的药酒配方为：麻黄10-20克、半边莲15-25克、桔梗10-20克、红茶5-15克、银杏叶25-35克、苎麻根25-35克、甘草10-20克、牛蒡子10-20克、薏米仁15-25克、米酒1000毫升；
所述降脂减肥的药酒配方为：泽泻10-20克、山楂15-25克、丹参2-10克、茵陈2-10克、水牛角2-10克、黄芪5-15克、厚朴10-20克、白术2-10克、川穹10-20克、银杏叶25-35克、何首乌5-15克、仙灵脾2-10克、大黄2-10克、苦丁茶2-10克、菊花2-10克、金银花2-10克、白茯苓2-10克、马尾连2-10克、大腹皮2-10克、桑叶5-15克、忍冬藤2-10克、干荷叶2-10克、神曲15-25克、三七粉2-10克、半夏2-10克、莱菔子2-10克、葛根2-10克、石斛10-20克、决明子10-20克、甘草2-10克、枣仁2-10克、槐米10-20克、米酒1000毫升。
一种用于治疗内脏脂肪堆积的中药制剂的制备方法，由治疗呼吸道的药酒制备方法和降脂减肥的药酒制备方法组成，所述治疗呼吸道的药酒制备方法包括以下步骤：将麻黄10-20克、半边莲15-25克、桔梗10-20克、红茶5-15克、银杏叶25-35克、苎麻根25-35克、甘草10-20克、牛蒡子10-20克、薏米仁15-25克全部研磨成粉末，与米酒1000毫升混合浸泡15-25天后，开封，过滤，灌装瓶中备用；
所述降脂减肥的药酒制备方法包括以下步骤：将泽泻10-20克、山楂15-25克、丹参2-10克、茵陈2-10克、水牛角2-10克、黄芪5-15克、厚朴10-20克、白术2-10克、川穹10-20克、银杏叶25-35克、何首乌5-15克、仙灵脾2-10克、大黄2-10克、苦丁茶2-10克、菊花2-10克、金银花2-10克、白茯苓2-10克、马尾连2-10克、大腹皮2-10克、桑叶5-15克、忍冬藤2-10克、干荷叶2-10克、神曲15-25克、三七粉2-10克、半夏2-10克、莱菔子2-10克、葛根2-10克、石斛10-20克、决明子10-20克、甘草2-10克、枣仁2-10克、槐米10-20克洗净晾干，研磨成粉末，与米酒1000毫升混合浸泡15-25天后，开封，过滤，灌装瓶中备用。
优选的，所述治疗呼吸道的药酒制备过程包括以下步骤：将麻黄15克、半边莲20克、桔梗15克、红茶10克、银杏叶30克、苎麻根30克、甘草15克、牛蒡子15克、薏米仁20克全部研磨成粉末，与九药曲米酒1000毫升混合浸泡20天后，开封，过滤，灌装瓶中，备用。
优选的，所述九药曲米酒是采用药曲制作的米酒，所述药曲的制作方法为：
(1)将麻黄10克、半边莲12克、桔梗10克、红茶l5克、银杏叶20克、苎麻根12克、甘草15克、牛蒡子12克、薏米仁10克洗净晾干，全部研磨成粉末，制成9种中药粉末备用：
(2)将大米加水浸泡4小时备用；
(3)把浸泡后的大米粉碎成米粉，并用180目的细筛进行过筛；
(4)以3/4的米粉用于做坯，余下1/4的米粉用作裹粉，将11种中药粉末全部裹粉，用量为坯粉重量的3％，陈曲粉为2％，水为60％，搅拌均匀；
(5)拌匀后制成酒饼，切成2厘米大小的粒状，并用竹筛筛圆成酒坯；
(6)把曲坯外面滚上一层细米粉，并控制酒坯含水量为46％；
(7)把酒坯送入曲室，室温控制在28～31℃；培养20小时后，霉菌菌丝生长旺盛，品温控制在33～34℃，最高不超过37℃；培养24小时后，为了促使曲坯中酵母繁殖，室温应控制在28～30℃，品温在35℃以下，保持24小时；入房共48小时后，品温下降，曲子成熟；
(8)成熟的曲取出后在烘房干燥或晒干，贮藏备用。
优选的，所述降脂减肥的药酒制备过程包括以下步骤：将泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克洗净晾干，研磨成粉末，与三十二药曲米酒1000毫升混合浸泡20天后，开封，过滤，灌装瓶中，备用。
优选的，所述三十二药曲米酒是采用药曲制作的米酒，所述药曲的制作方法为：
(1)将将洗净、晾干的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米5克全部研磨成粉末，制成32种中药粉末备用；
(2)将大米加水浸泡4小时备用；
(3)把浸泡后的大米粉碎成米粉，并用180目的细筛进行过筛；
(4)以3/4的米粉用于做坯，余下1/4的米粉用作裹粉，将11种中药粉末全部裹粉，用量为坯粉重量的3％，陈曲粉为2％，水为60％，搅拌均匀；
(5)拌匀后制成酒饼，切成2厘米大小的粒状，并用竹筛筛圆成酒坯；
(6)把曲坯外面滚上一层细米粉，并控制酒坯含水量为46％；
(7)把酒坯送入曲室，室温控制在28～31℃；培养20小时后，霉菌菌丝生长旺盛，品温控制在33～34℃，最高不超过37℃；培养24小时后，为了促使曲坯中酵母繁殖，室温应控制在28～30℃，品温在35℃以下，保持24小时；入房共48小时后，品温下降，曲子成熟；
(8)成熟的曲取出后在烘房干燥或晒干，贮藏备用。
优选的，所述治疗呼吸道的药酒由口服液替代，所述治疗呼吸道的口服液制备过程包括以下步骤：用传统工艺将洗净、晾干、切碎的麻黄10克、半边莲12克、桔梗10克、红茶15克、银杏叶20克、苎麻根12克、甘草15克、牛蒡子12克、薏米仁10克这九种中药材，加入2000毫升水煮至1000毫升浓缩液，冷却过滤后，加入所述九药曲米酒100毫升。
优选的，所述降脂减肥的药酒由口服液替代，所述降脂减肥的口服液制备过程包括以下步骤：用传统工艺将洗净、晾干、切碎的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克这三十二种药材，用水2000毫升煮至1000毫升中药浓缩液，冷却过滤后，加入所述三十二药曲米酒100毫升。
优选的，所述治疗呼吸道的药酒由蜜丸替代，所述治疗呼吸道的蜜丸制备过程包括以下步骤：将麻黄15克、半边莲20克、桔梗15克、红茶10克、银杏叶30克、苎麻根30克、甘草15克、牛蒡子15克、薏米仁20克全部研磨成粉末，溶剂采用所述九药曲米酒，利用传统工艺制成蜜丸。
优选的，所述降脂减肥的药酒由蜜丸替代，所述降脂减肥的蜜丸制备过程包括以下步骤：将泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克全部研磨成粉末，溶剂采用三十二药曲米酒，利用传统工艺制成蜜丸。
在治疗高脂肥胖症过程，我们发现了一个普遍现象就是发胖和脂肪高的人呼吸都不畅通，睡觉时多伴有打呼噜。因此本发明配方有两个，第一个配方是主治上呼吸道的慢性鼻炎和打呼噜，在治疗上呼吸道的过程顺便也治疗下呼吸道的支气管炎症和肺虚症，这样就保证了上下呼吸道的畅通；第二个配方是主治内脂脂肪高的症状和皮下堆积的可变脂。第一个配方是为第二个降脂减肥配方的实施提供保障。
在本专利配方一的实施过程，要求患者在傍晚，空气含氧量高时，在户外做有氧运动，特别是扩胸运动，增加肺活量锻炼，并且在家中用250毫升矿泉水瓶盛半瓶水，瓶中插入吸管，用口快速对吸管吹气，然后对空吸气再次对吸管往瓶中水里吹气，这种训练每天傍晚坚持20分钟。这种憋气训练对提高肺部分解脂肪时二氧化碳的吐出能力和大量吸进氧气有帮助。
由于采用了上述技术方案，本发明具有如下有益效果：
1、本发明对脂肪在体内分解代谢有促进作用。一般来讲肝和小肠是脂肪合成的重要场所。肝的合成能力最强，肝细胞能合成脂肪，但不能储存脂肪，合成后要与载体蛋白、胆固醇等结合成极低密度脂蛋白，入血运到肝外组织储存或加以利用，若肝合成的甘油三酯不能及时转运，会形成脂肪肝，本配方中有多种中药对甘油三酯有分解作用。小肠生成的脂肪是由甘油一酯和脂肪酸合成甘油三酯，本中药中的多种中药对合成甘油三酯过程有干扰作用。
2、本发明对脂肪肝的治愈率较高，对内脏脂肪的降低率较高，对高血脂伴有高血压的治愈率较高。
3、传统制作中药蜜丸使用水作为溶剂，由于本发明制作的中药蜜丸中含有少许酒精，使得中药蜜丸保质期延长，同时蜜丸服用后，药物中残留的酒精能都助药物迅速扩散到人体的各个部位，使得治疗效果大大提高。
具体实施方式
通过下面的实施例可以详细的解释本发明，公开本发明的目的旨在保护本发明范围内的一切技术改进。
实施例一 治疗呼吸道的药酒制备
将大米及糯米加入药曲及适量陈曲，按传统工艺制作九种药曲米酒，用制作的九种药曲米酒1000毫升加入洗净、晾干、切碎的麻黄15克、半边莲20克、桔梗15克、红茶10克、银杏叶30克、苎麻根30克、甘草15克、牛蒡子15克、薏米仁20克，浸泡20天后，过滤去渣。
实施例二 治疗呼吸道的口服液制备
1、用传统工艺将洗净、晾干、切碎的麻黄10克、半边莲12克、桔梗10克、红茶15克、银杏叶20克、苎麻根12克、甘草15克、牛蒡子12克、薏米仁10克，加入2000毫升水煮至剩下1000毫升浓缩液，冷却、过滤，备用；
2、100毫升九药曲米酒药酒加入1000毫升浓缩液，治疗呼吸道的口服液制成。
实施例三 治疗呼吸道的蜜丸制备
将适量的九药曲米酒与全部研磨成粉末的麻黄15克、半边莲20克、桔梗15克、红茶10克、银杏叶30克、苎麻根30克、甘草15克、牛蒡子15克、薏米仁20克药材，采用传统工艺制成蜜丸。
实施例四 降脂减肥的三十二药曲米酒药酒制备
将大米及糯米加入药曲及适量陈曲，按传统工艺制作降脂减肥的三十二药曲米酒，将制成的三十二药曲米酒1000毫升加入洗净、晾干、切碎的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克这32种药材，密封浸泡20天后，开封、过滤、灌装，降脂减肥的三十二药曲米酒药酒制成。
实施例五 降脂减肥口服液制备
1、用传统工艺将洗净、晾干、切碎的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克这32种药材，用水2000毫升煮至水剩1000毫升32种中药浓缩液，过滤去渣。
2、用100毫升32种药曲米酒加入1000毫升32种中药浓缩液，制成降脂减肥口服液。
实施例六 降脂减肥的蜜丸制备
将适量的三十二药曲米酒与全部研磨成粉末的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克药材，采用传统工艺制成蜜丸。
实施例七 试验治疗效果
成年人体脂肪含量正常值为19％，如果脂肪含量达到35％以上，会伴有脂肪肝、人体肥胖，凡血清胆固醇在220mg％以上，β脂蛋白在450mg％以上，甘油三酯在50mg％以上，均作为治疗对象，除孕妇禁用。
本试验101例患者中，血清胆固醇增高者66例，β脂蛋白增高者81例，甘油三酯增高者64例，三项均增高者29例。全病例均做物理检查，血常规检查、胸x透视、心电图、眼底检查、尿常规检查，发现合并高血压2例，合并慢性冠状动脉供血不足10例，眼底发现动脉硬化59例。
对所有患者采用治疗呼吸道的药酒或口服液、蜜丸，使用15天到20天，对呼吸道进行清理性治疗后，再采用降脂减肥的药酒或口服液、蜜丸实施2-3个月的治疗。每人每天服药三次，服药酒按每次10毫升，服蜜丸每次6克，45天为一疗程，在治疗过程中，病人不受饮食限制，运动量如常。
疗效分析：
从表1可以看出，66例高胆固醇血症治疗前血清胆固醇平均值为264mg％，治疗后平均值为200mg％，平均值下降64.0mg％(P＜0.01，差异非常显著)；81例高β脂蛋白血症，治疗前血清β脂蛋白平均为555mg％，治疗后平均值为460mg％，平均降值为95mg％(P＜0.01，差异非常显著)；64例高甘油三酯血症，治疗前血清甘油三酯平均值为213mg％，治疗后为139mg％，平均下降值为74mg％(P＜0.01，差异非常显著)。
表1治疗前后血脂值变化
对高脂血症的疗效，目前尚无统一标准，通过治疗前后血脂值比较，以下降50mg％以上为显著疗效，下降20mg％以上为有效疗效，下降20mg％以下或波动或反而升高者为无效治疗。本组病人治疗后血脂值变化幅度列表如下：
表2高胆固醇血症66例治愈率
从表2可以看出，治疗高胆固醇血症有显著疗效为56.1％，有疗效为379％，无疗效为6％。
表3高β脂蛋白血症81例治愈率
从表三可以看出，治疗高β脂蛋白血症有显著疗效为58.0％，有疗效为28.4％，无效率为13.6％。
表4高甘油三酯血症64例治愈率
从表四可以看出，治疗高甘油三酯血症有显著疗效为71.8％，有疗效为17.3％，无疗效为10.9％。
101例大多数服药时间为30天至45天，其中少数病人服药后30天血脂降至正常值，极少数病人服药70天以上，血脂仍未降至正常值，在统计时作为无效处理。4例病人服药35天后，血脂降至正常，停药一月后复查血脂又升高，继续一步法仅服降脂药，15天至20天后血脂又恢复正常。有58例腰腹部明显减肥，体重平均降低8％。有72例坚持服药90天的肥胖型血脂症病人，66人都明显减肥，体重平均降低10.2％。大部分病人服药后，自觉症状好转，食欲增加，睡眠改善(打呼噜症状减轻或消失)，服药后无不良反应，仅有一名十二指肠溃疡病人，服药后反酸上腹痛加重而自动停药。
在参与治疗试验的患者中，有三位女性因盲目节食瘦身造成脂肪肝，被全部治愈，这与配方中加入具抗氧化的中药有关；降脂的患者中有82％以上减肥效果明显，18％以下的患者减肥不明显可能与遗传因素有关；对高血脂症患者进行治疗，85％以上血压明显改善。
本发明未详述部分为现有技术。
以上所述仅是本发明的优选实施方式，本发明的保护范围并不仅局限于上述实施例，凡属于本发明思路下的技术方案均属于本发明的保护范围。应当指出，对于本技术领域的普通技术人员来说，在不脱离本发明原理前提下的若干改进和润饰，这些改进和润饰也应视为本发明的保护范围。
Claims (10)
1.一种用于治疗内脏脂肪堆积的中药制剂，由治疗呼吸道的药酒和降脂减肥的药酒组成，其特征在于：
所述治疗呼吸道的药酒配方为：麻黄10-20克、半边莲15-25克、桔梗10-20克、红茶5-15克、银杏叶25-35克、苎麻根25-35克、甘草10-20克、牛蒡子10-20克、薏米仁15-25克、米酒1000毫升；
所述降脂减肥的药酒配方为：泽泻10-20克、山楂15-25克、丹参2-10克、茵陈2-10克、水牛角2-10克、黄芪5-15克、厚朴10-20克、白术2-10克、川穹10-20克、银杏叶25-35克、何首乌5-15克、仙灵脾2-10克、大黄2-10克、苦丁茶2-10克、菊花2-10克、金银花2-10克、白茯苓2-10克、马尾连2-10克、大腹皮2-10克、桑叶5-15克、忍冬藤2-10克、干荷叶2-10克、神曲15-25克、三七粉2-10克、半夏2-10克、莱菔子2-10克、葛根2-10克、石斛10-20克、决明子10-20克、甘草2-10克、枣仁2-10克、槐米10-20克、米酒1000毫升。
2.一种用于治疗内脏脂肪堆积的中药制剂的制备方法，由治疗呼吸道的药酒制备方法和降脂减肥的药酒制备方法组成，其特征在于：
所述治疗呼吸道的药酒制备方法包括以下步骤：将麻黄10-20克、半边莲15-25克、桔梗10-20克、红茶5-15克、银杏叶25-35克、苎麻根25-35克、甘草10-20克、牛蒡子10-20克、薏米仁15-25克全部研磨成粉末，与米酒1000毫升混合浸泡15-25天后，开封，过滤，灌装瓶中备用；
所述降脂减肥的药酒制备方法包括以下步骤：将泽泻10-20克、山楂15-25克、丹参2-10克、茵陈2-10克、水牛角2-10克、黄芪5-15克、厚朴10-20克、白术2-10克、川穹10-20克、银杏叶25-35克、何首乌5-15克、仙灵脾2-10克、大黄2-10克、苦丁茶2-10克、菊花2-10克、金银花2-10克、白茯苓2-10克、马尾连2-10克、大腹皮2-10克、桑叶5-15克、忍冬藤2-10克、干荷叶2-10克、神曲15-25克、三七粉2-10克、半夏2-10克、莱菔子2-10克、葛根2-10克、石斛10-20克、决明子10-20克、甘草2-10克、枣仁2-10克、槐米10-20克洗净晾干，研磨成粉末，与米酒1000毫升混合浸泡15-25天后，开封，过滤，灌装瓶中备用。
3.根据权利要求2所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述治疗呼吸道的药酒制备过程包括以下步骤：将麻黄15克、半边莲20克、桔梗15克、红茶10克、银杏叶30克、苎麻根30克、甘草15克、牛蒡子15克、薏米仁20克全部研磨成粉末，与九药曲米酒1000毫升混合浸泡20天后，开封，过滤，灌装瓶中，备用。
4.根据权利要求3所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述九药曲米酒是采用药曲制作的米酒，所述药曲的制作方法为：
(1)将麻黄10克、半边莲12克、桔梗10克、红茶15克、银杏叶20克、苎麻根12克、甘草15克、牛蒡子12克、薏米仁10克洗净晾干，全部研磨成粉末，制成9种中药粉末备用；
(2)将大米加水浸泡4小时备用；
(3)把浸泡后的大米粉碎成米粉，并用180目的细筛进行过筛；
(4)以3/4的米粉用于做坯，余下1/4的米粉用作裹粉，将11种中药粉末全部裹粉，用量为坯粉重量的3％，陈曲粉为2％，水为60％，搅拌均匀；
(5)拌匀后制成酒饼，切成2厘米大小的粒状，并用竹筛筛圆成酒坯；
(6)把曲坯外面滚上一层细米粉，并控制酒坯含水量为46％；
(7)把酒坯送入曲室，室温控制在28～31℃；培养20小时后，霉菌菌丝生长旺盛，品温控制在33～34℃，最高不超过37℃；培养24小时后，为了促使曲坯中酵母繁殖，室温应控制在28～30℃，品温在35℃以下，保持24小时；入房共48小时后，品温下降，曲子成熟；
(8)成熟的曲取出后在烘房干燥或晒干，贮藏备用。
5.根据权利要求2所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述降脂减肥的药酒制备过程包括以下步骤：将泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克洗净晾干，研磨成粉末，与三十二药曲米酒1000毫升混合浸泡20天后，开封，过滤，灌装瓶中，备用。
6.根据权利要求5所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述三十二药曲米酒是采用药曲制作的米酒，所述药曲的制作方法为：
(1)将将洗净、晾干的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米5克全部研磨成粉末，制成32种中药粉末备用；
(2)将大米加水浸泡4小时备用；
(3)把浸泡后的大米粉碎成米粉，并用180目的细筛进行过筛；
(4)以3/4的米粉用于做坯，余下1/4的米粉用作裹粉，将11种中药粉末全部裹粉，用量为坯粉重量的3％，陈曲粉为2％，水为60％，搅拌均匀；
(5)拌匀后制成酒饼，切成2厘米大小的粒状，并用竹筛筛圆成酒坯；
(6)把曲坯外面滚上一层细米粉，并控制酒坯含水量为46％：
(7)把酒坯送入曲室，室温控制在28～31℃；培养20小时后，霉菌菌丝生长旺盛，品温控制在33～34℃，最高不超过37℃；培养24小时后，为了促使曲坯中酵母繁殖，室温应控制在28～30℃，品温在35℃以下，保持24小时；入房共48小时后，品温下降，曲子成熟；
(8)成熟的曲取出后在烘房干燥或晒干，贮藏备用。
7.根据权利要求3或4所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述治疗呼吸道的药酒由口服液替代，所述治疗呼吸道的口服液制备过程包括以下步骤：用传统工艺将洗净、晾干、切碎的麻黄10克、半边莲12克、桔梗10克、红茶15克、银杏叶20克、苎麻根12克、甘草15克、牛蒡子12克、薏米仁10克这九种中药材，加入2000毫升水煮至1000毫升浓缩液，冷却过滤后，加入所述九药曲米酒100毫升。
8.根据权利要求5或6所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述降脂减肥的药酒由口服液替代，所述降脂减肥的口服液制备过程包括以下步骤：用传统工艺将洗净、晾干、切碎的泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克这三十二种药材，用水2000毫升煮至1000毫升中药浓缩液，冷却过滤后，加入所述三十二药曲米酒100毫升。
9.根据权利要求3或4所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述治疗呼吸道的药酒由蜜丸替代，所述治疗呼吸道的蜜丸制备过程包括以下步骤：将麻黄15克、半边莲20克、桔梗15克、红茶10克、银杏叶30克、苎麻根30克、甘草15克、牛蒡子15克、薏米仁20克全部研磨成粉末，溶剂采用所述九药曲米酒，利用传统工艺制成蜜丸。
10.根据权利要求5或6所述的一种用于治疗内脏脂肪堆积的中药制剂的制备方法，其特征在于：所述降脂减肥的药酒由蜜丸替代，所述降脂减肥的蜜丸制备过程包括以下步骤：将泽泻15克、山楂20克、丹参5克、茵陈5克、水牛角3克、黄芪10克、厚朴15克、白术4克、川穹15克、银杏叶30克、何首乌10克、仙灵脾5克、大黄3克、苦丁茶5克、菊花5克、金银花5克、白茯苓5克、马尾连5克、大腹皮5克、桑叶10克、忍冬藤5克、干荷叶5克、神曲20克、三七粉3克、半夏3克、莱菔子3克、葛根3克、石斛15克、决明子12克、甘草3克、枣仁3克、槐米15克全部研磨成粉末，溶剂采用三十二药曲米酒，利用传统工艺制成蜜丸。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110928227.2A CN113425815A (zh) | 2021-08-13 | 2021-08-13 | 一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110928227.2A CN113425815A (zh) | 2021-08-13 | 2021-08-13 | 一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN113425815A true CN113425815A (zh) | 2021-09-24 |
Family
ID=77797623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110928227.2A Pending CN113425815A (zh) | 2021-08-13 | 2021-08-13 | 一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN113425815A (zh) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1145799A (zh) * | 1996-07-08 | 1997-03-26 | 张炬 | 消鼾口服液 |
| CN101053400A (zh) * | 2007-05-11 | 2007-10-17 | 陈江 | 男性减肥口服液 |
| CN103784628A (zh) * | 2012-10-31 | 2014-05-14 | 吕奎荣 | 一种治疗肥胖症的中药制备方法 |
| CN105832923A (zh) * | 2016-04-18 | 2016-08-10 | 宝应县中医医院 | 一种降脂胶囊及其制作工艺 |
-
2021
- 2021-08-13 CN CN202110928227.2A patent/CN113425815A/zh active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1145799A (zh) * | 1996-07-08 | 1997-03-26 | 张炬 | 消鼾口服液 |
| CN101053400A (zh) * | 2007-05-11 | 2007-10-17 | 陈江 | 男性减肥口服液 |
| CN103784628A (zh) * | 2012-10-31 | 2014-05-14 | 吕奎荣 | 一种治疗肥胖症的中药制备方法 |
| CN105832923A (zh) * | 2016-04-18 | 2016-08-10 | 宝应县中医医院 | 一种降脂胶囊及其制作工艺 |
Non-Patent Citations (3)
| Title |
|---|
| 晋可: "酒曲制作方法", 农村新技术, pages 50 - 51 * |
| 曲巧敏;: "宣肺消鼾汤治疗睡眠呼吸暂停综合征86例临床观察", 江苏中医药, vol. 43, no. 03, pages 42 * |
| 栾泰平;郝有孝;: "降脂清脑汤治疗高血脂70例", 陕西中医, no. 09, pages 1180 - 1181 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107296949A (zh) | 药食同源复合制剂及其制备方法和应用 | |
| CN112546167A (zh) | 一种具有健脾利湿功能的中药组合物及其制备方法和应用 | |
| CN106173605A (zh) | 一种包含葛根和石斛的降血糖保健组合物 | |
| CN100584359C (zh) | 用于肥胖及其并发症的药物 | |
| CN102335358A (zh) | 一种治疗心律失常的中药制剂 | |
| CN108619295A (zh) | 一种调理小儿遗尿的保健药贴及其加工方法 | |
| CN108310156A (zh) | 一种治疗儿科腹泻的中药组合物及其制备方法 | |
| CN113425815A (zh) | 一种用于治疗内脏脂肪堆积的中药制剂及其制备方法和应用 | |
| CN112023010A (zh) | 一种瘦身用中药组合物及其制备方法、口服药剂和应用 | |
| CN106177476A (zh) | 一种包含石斛和陈皮的降血糖保健组合物 | |
| CN104173699A (zh) | 一种防治口腔溃疡的咀嚼片及其制备方法 | |
| CN112957386B (zh) | 一种中药饮片的炮制方法 | |
| CN114588228B (zh) | 一种治疗2型糖尿病的组合物 | |
| CN110170027B (zh) | 一种山楂红曲粉丸剂及其制备方法 | |
| CN106620367A (zh) | 一种治疗膀胱结石的中药缓释胶囊及制备方法 | |
| CN102166300B (zh) | 治疗肺部阴虚、胃部阴虚及消渴病阴虚症状的中药制剂 | |
| CN101810751B (zh) | 一种治疗小儿肠系膜淋巴结发炎的中药制剂 | |
| CN108186874B (zh) | 一种治疗糖尿病的中药组合物 | |
| CN101695543B (zh) | 一种治疗心率失常的组合物及其制备方法 | |
| CN106728645A (zh) | 一种家畜催乳的中药复方组合物 | |
| CN105232975A (zh) | 改善盗汗症状的制剂及制法 | |
| CN105287736A (zh) | 一种医治肺气肿的中药组合物及制法 | |
| CN102319349A (zh) | 一种治疗肺炎的中药组合物及其制备方法 | |
| CN105194433A (zh) | 一种内科治疗老年体虚症的中药组合物 | |
| CN104857242A (zh) | 一种治疗小儿疳积的健脾消食剂及制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| DD01 | Delivery of document by public notice |
Addressee: Shan Ke Document name: Notification of qualification for preliminary examination of patent application for invention |
|
| DD01 | Delivery of document by public notice | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20210924 |
|
| WD01 | Invention patent application deemed withdrawn after publication |