CN113412936A - 一种肌少症患者的肠内营养制剂 - Google Patents
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Abstract
本发明公开了一种肌少症患者的肠内营养制剂。本发明的肌少症患者的肠内营养制剂包括乳清蛋白、亮氨酸，β‑羟基‑β‑甲基丁酸(β‑hydroxy‑β‑methylbutyrate，HMB)，维生素D、其他维生素和微量元素。本发明的配方中以乳清蛋白为主，并辅以亮氨酸及其代谢物HMB作为主要营养素，患者服用后体内吸收消化速度快，餐后促蛋白质合成作用好，可以增加患者肌肉的强度。本发明的肠内营养制剂富含乳清蛋白、亮氨酸、HMB、维生素D，可以改善肌少症患者的肌肉质量和力量，可作为治疗肌少症的专用营养补充剂。
Description
技术领域
本发明涉及一种肌少症患者的肠内营养制剂，属于营养补充剂技术领域。
背景技术
营养疗法是肌少症患者重要的治疗手段，但目前市场上常用的口服肠内营养制剂配方中蛋白含量低，而且以酪蛋白为主，不适合用于肌少症患者，目前国内尚无专门针对肌少症患者的肠内营养制剂。
发明内容
本发明解决的技术问题是：目前市场上常用的口服肠内营养制剂配方中蛋白含量低，而且以酪蛋白为主，不适合用于肌少症患者。
为了解决上述技术问题，本发明提供了一种肌少症患者的肠内营养制剂，该肠内营养制剂的成分包括乳清蛋白、亮氨酸、β-羟基-β-甲基丁酸HMB、维生素和微量元素；所述的维生素包括维生素D。
优选地，所述的维生素还包括维生素C、维生素A、维生素E、类胡萝卜素、微生物K1、叶酸、维生素B1、维生素B2、维生素B6、维生素B12、烟酸、泛酸和生物素。
优选地，所述的微量元素包括钠、钾、氯、钙、锌、镁、磷、硒和钼。
优选地，所述的肠内营养制剂的成分还包括碳水化合物、脂肪、膳食纤维和胆碱。
优选地，每100g所述的肠内营养制剂中包含乳清蛋白50-60克、亮氨酸5-6克、β-羟基-β-甲基丁酸HMB 5-6克、碳水化合物15-30克、脂肪5-6克、维生素D 2000U、膳食纤维4g、钠420mg、钾650mg、氯520mg、钙200mg、锌5mg、镁84mg、磷250mg、硒22μg、钼39μg、维生素C40mg、维生素A 420μg RE、维生素E 5.2mgα-TE、类胡萝卜素0.95mg、维生素K1 16μg、叶酸220μg、维生素B1 0.81mg、维生素B2 0.72mg、维生素B6 1.1mg、维生素B12 1μg、烟酸11mg、泛酸4mg、生物素14μg和胆碱110mg。
本发明与现有技术相比，具有如下有益效果：
1.本发明的肠内营养制剂富含乳清蛋白、亮氨酸、HMB、维生素D，可以改善肌少症患者的肌肉质量和力量，可作为治疗肌少症的专用营养补充剂；
2.本发明的配方中以乳清蛋白为主，并辅以亮氨酸及其代谢物HMB作为主要营养素，亮氨酸可以激活蛋白质合成的信号通路，其促蛋白质合成能力比其他氨基酸高10倍，而骨骼肌量的稳定主要依赖肌蛋白合成与分解代谢的动态平衡，因此本发明的场内营养制剂乳清蛋白的亮氨酸含量高，体内吸收消化速度快，餐后促蛋白质合成作用好，可以增加患者肌肉的强度。
具体实施方式
为使本发明更明显易懂，兹以优选实施例，作详细说明如下。
实施例1
一种肌少症患者的肠内营养制剂，每100g肠内营养制剂含有以下营养素：乳清蛋白60克、亮氨酸6克、HMB(β-羟基-β-甲基丁酸)6克、碳水化合物15克、脂肪6克、维生素D2000U、膳食纤维4g、钠420mg、钾650mg、氯520mg、钙200mg、锌5mg、镁84mg、磷250mg、硒22μg、钼39μg、维生素C 40mg、维生素A 420μg RE、维生素E 5.2mgα-TE、类胡萝卜素0.95mg、维生素K1 16μg、叶酸220μg、维生素B1 0.81mg、维生素B2 0.72mg、维生素B6 1.1mg、维生素B121μg、烟酸11mg、泛酸4mg、生物素14μg和胆碱110mg。
实施例2
一种肌少症患者的肠内营养制剂，每100g肠内营养制剂含有以下营养素：乳清蛋白50克、亮氨酸5克、HMB(β-羟基-β-甲基丁酸)5克、碳水化合物28克、脂肪5克、维生素D2000U、膳食纤维4g、钠420mg、钾650mg、氯520mg、钙200mg、锌5mg、镁84mg、磷250mg、硒22μg、钼39μg、维生素C 40mg、维生素A 420μg RE、维生素E 5.2mgα-TE、类胡萝卜素0.95mg、维生素K1 16μg、叶酸220μg、维生素B1 0.81mg、维生素B2 0.72mg、维生素B6 1.1mg、维生素B121μg、烟酸11mg、泛酸4mg、生物素14μg和胆碱110mg。
实施例3
一种肌少症患者的肠内营养制剂，每100g肠内营养制剂含有以下营养素：乳清蛋白54克、亮氨酸5.4克、HMB(β-羟基-β-甲基丁酸)5.4克、碳水化合物22.8克、脂肪5.4克、维生素D 2000U、膳食纤维4g、钠420mg、钾650mg、氯520mg、钙200mg、锌5mg、镁84mg、磷250mg、硒22μg、钼39μg、维生素C 40mg、维生素A 420μg RE、维生素E 5.2mgα-TE、类胡萝卜素0.95mg、维生素K1 16μg、叶酸220μg、维生素B1 0.81mg、维生素B2 0.72mg、维生素B61.1mg、维生素B12 1μg、烟酸11mg、泛酸4mg、生物素14μg和胆碱110mg。
以上所述，仅为本发明的较佳实施例，并非对本发明任何形式上和实质上的限制，应当指出，对于本技术领域的普通技术人员，在不脱离本发明的前提下，还将可以做出若干改进和补充，这些改进和补充也应视为本发明的保护范围。
Claims (5)
1.一种肌少症患者的肠内营养制剂，其特征在于，该肠内营养制剂的成分包括乳清蛋白、亮氨酸、β-羟基-β-甲基丁酸HMB、维生素和微量元素；所述的维生素包括维生素D。
2.如权利要求1所述的肌少症患者的肠内营养制剂，其特征在于，所述的维生素还包括维生素C、维生素A、维生素E、类胡萝卜素、微生物K1、叶酸、维生素B1、维生素B2、维生素B6、维生素B12、烟酸、泛酸和生物素。
3.如权利要求1所述的肌少症患者的肠内营养制剂，其特征在于，所述的微量元素包括钠、钾、氯、钙、锌、镁、磷、硒和钼。
4.如权利要求1所述的肌少症患者的肠内营养制剂，其特征在于，所述的肠内营养制剂的成分还包括碳水化合物、脂肪、膳食纤维和胆碱。
5.如权利要求1所述的肌少症患者的肠内营养制剂，其特征在于，每100g所述的肠内营养制剂中包含乳清蛋白50-60克、亮氨酸5-6克、β-羟基-β-甲基丁酸HMB 5-6克、碳水化合物15-30克、脂肪5-6克、维生素D 2000U、膳食纤维4g、钠420mg、钾650mg、氯520mg、钙200mg、锌5mg、镁84mg、磷250mg、硒22μg、钼39μg、维生素C 40mg、维生素A 420μg RE、维生素E 5.2mgα-TE、类胡萝卜素0.95mg、维生素K1 16μg、叶酸220μg、维生素B1 0.81mg、维生素B20.72mg、维生素B6 1.1mg、维生素B12 1μg、烟酸11mg、泛酸4mg、生物素14μg和胆碱110mg。
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