CN113366025A - 交联的聚合物网络及其用途 - Google Patents

交联的聚合物网络及其用途 Download PDF

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Publication number
CN113366025A
CN113366025A CN202080009811.1A CN202080009811A CN113366025A CN 113366025 A CN113366025 A CN 113366025A CN 202080009811 A CN202080009811 A CN 202080009811A CN 113366025 A CN113366025 A CN 113366025A
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CN
China
Prior art keywords
glycosaminoglycan
crosslinked polymer
polymer network
gag
crosslinked
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080009811.1A
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English (en)
Chinese (zh)
Inventor
G·L·格鲁伯三世
A·K·阿瓦斯蒂
M·R·米斯
J·L·沃尔克特
J·R·豪因斯泰因
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Bausch and Lomb Inc
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Bausch and Lomb Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bausch and Lomb Inc filed Critical Bausch and Lomb Inc
Publication of CN113366025A publication Critical patent/CN113366025A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A45—HAND OR TRAVELLING ARTICLES
    • A45C—PURSES; LUGGAGE; HAND CARRIED BAGS
    • A45C11/00—Receptacles for purposes not provided for in groups A45C1/00-A45C9/00
    • A45C11/005—Contact lens cases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B25/00—Packaging other articles presenting special problems
    • B65B25/008—Packaging other articles presenting special problems packaging of contact lenses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • G—PHYSICS
    • G02—OPTICS
    • G02C—SPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00—Optical parts
    • G02C7/02—Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04—Contact lenses for the eyes
    • G02C7/049—Contact lenses having special fitting or structural features achieved by special materials or material structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Eyeglasses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
CN202080009811.1A 2019-01-30 2020-01-10 交联的聚合物网络及其用途 Pending CN113366025A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962798668P 2019-01-30 2019-01-30
US62/798,668 2019-01-30
PCT/US2020/013057 WO2020159690A1 (en) 2019-01-30 2020-01-10 Crosslinked polymeric network and use thereof

Publications (1)

Publication Number Publication Date
CN113366025A true CN113366025A (zh) 2021-09-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080009811.1A Pending CN113366025A (zh) 2019-01-30 2020-01-10 交联的聚合物网络及其用途

Country Status (8)

Country Link
US (3) US11732060B2 (https=)
EP (1) EP3917973A1 (https=)
JP (2) JP7492967B2 (https=)
KR (1) KR102793214B1 (https=)
CN (1) CN113366025A (https=)
CA (1) CA3125761A1 (https=)
MX (1) MX2021008711A (https=)
WO (1) WO2020159690A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115819983A (zh) * 2022-11-30 2023-03-21 中欧电子材料国际创新中心(合肥)有限公司 一种含八重氢键的交联型硅橡胶及其制备方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115040699A (zh) * 2021-03-09 2022-09-13 上海硕创生物医药科技有限公司 热固化透明质酸钠涂层、医用导管及器械
EP4328659A1 (en) * 2021-04-19 2024-02-28 National Institute for Materials Science Soft ophthalmic lens and method for manufacturing same
US12012238B2 (en) * 2021-05-26 2024-06-18 Bausch + Lomb Ireland Limited Packaging solutions
DE102021212812A1 (de) 2021-11-15 2023-05-17 Bauerfeind Ag Entzündungshemmendes viskosupplementierendes Mittel enthaltend Hyaluronsäure
US20230159202A1 (en) * 2021-11-23 2023-05-25 Bausch + Lomb Ireland Limited Method for making a preservative-free packaged ophthalmic device product
US12212355B2 (en) * 2022-09-05 2025-01-28 Mirza Faizan Biodegradable cover for a portable electronic device

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1075970A (zh) * 1992-02-05 1993-09-08 生化学工业株式会社 可光硫化的药糖氨基聚糖衍生物，交联葡糖氨基聚糖及其生产方法
US5731298A (en) * 1992-01-03 1998-03-24 Reinmuller; Johannes Method for the treatment of scars and keloids
EP2011816A1 (fr) * 2007-07-05 2009-01-07 Estelle Piron Gel co-réticulé de polysaccharides
CN101502675A (zh) * 2008-02-04 2009-08-12 山东省药学科学院 一种注射用含大分子水凝胶的透明质酸或其盐的混悬液及其制备方法
CN101721349A (zh) * 2008-10-16 2010-06-09 常州百瑞吉生物医药有限公司 可注射原位交联水凝胶及其制备方法和用途
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
CN102911380A (zh) * 2012-10-29 2013-02-06 北京爱美客生物科技有限公司 透明质酸与生物可降解高分子改性材料及制备方法
CN104220078A (zh) * 2012-03-30 2014-12-17 菲迪亚医药公司 包括硫酸软骨素和透明质酸衍生物的药物制剂
CN104225677A (zh) * 2013-06-13 2014-12-24 山东省生物药物研究院 交联透明质酸细胞支架材料及其制备方法和应用
US20170143870A1 (en) * 2014-04-01 2017-05-25 Merz Pharma Gmbh & Co. Kgaa Polysaccharide soft tissue fillers with improved persistence
EP3187510A1 (en) * 2015-12-29 2017-07-05 Galderma S.A. Carbohydrate crosslinker

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL285986A (https=) 1961-12-27
NL128305C (https=) 1963-09-11
US4197266A (en) 1974-05-06 1980-04-08 Bausch & Lomb Incorporated Method for forming optical lenses
US4113224A (en) 1975-04-08 1978-09-12 Bausch & Lomb Incorporated Apparatus for forming optical lenses
US4143949A (en) 1976-10-28 1979-03-13 Bausch & Lomb Incorporated Process for putting a hydrophilic coating on a hydrophobic contact lens
US4136250A (en) 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4153641A (en) 1977-07-25 1979-05-08 Bausch & Lomb Incorporated Polysiloxane composition and contact lens
US4312575A (en) 1979-09-18 1982-01-26 Peyman Gholam A Soft corneal contact lens with tightly cross-linked polymer coating and method of making same
US4555732A (en) 1984-03-22 1985-11-26 Xerox Corporation Image sensor correction system
US4758595A (en) 1984-12-11 1988-07-19 Bausch & Lomb Incorporated Disinfecting and preserving systems and methods of use
US4740533A (en) 1987-07-28 1988-04-26 Ciba-Geigy Corporation Wettable, flexible, oxygen permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
US5271876A (en) 1986-12-02 1993-12-21 Solomat Partners, L.P. Process for analyzing, monitoring and/or controlling the internal structure of non-conductive, moldable material by inducing an electrical effect therein before it is molded
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
US4910277A (en) 1988-02-09 1990-03-20 Bambury Ronald E Hydrophilic oxygen permeable polymers
US4954587A (en) 1988-07-05 1990-09-04 Ciba-Geigy Corporation Dimethylacrylamide-copolymer hydrogels with high oxygen permeability
US5070215A (en) 1989-05-02 1991-12-03 Bausch & Lomb Incorporated Novel vinyl carbonate and vinyl carbamate contact lens material monomers
US5034461A (en) 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5010141A (en) 1989-10-25 1991-04-23 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5079319A (en) 1989-10-25 1992-01-07 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
JP2933999B2 (ja) * 1990-08-24 1999-08-16 トーメー産業株式会社 コンタクトレンズの親水化方法
US5310779A (en) 1991-11-05 1994-05-10 Bausch & Lomb Incorporated UV curable crosslinking agents useful in copolymerization
US5358995A (en) 1992-05-15 1994-10-25 Bausch & Lomb Incorporated Surface wettable silicone hydrogels
US5260000A (en) 1992-08-03 1993-11-09 Bausch & Lomb Incorporated Process for making silicone containing hydrogel lenses
IL106922A (en) 1992-09-14 1998-08-16 Novartis Ag Composite materials with one or more wettable surfaces and process for their preparation
US5321108A (en) 1993-02-12 1994-06-14 Bausch & Lomb Incorporated Fluorosilicone hydrogels
US5616757A (en) 1993-04-08 1997-04-01 Bausch & Lomb Incorporated Organosilicon-containing materials useful for biomedical devices
US5573726A (en) 1993-09-22 1996-11-12 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
CA2162394A1 (en) * 1994-03-14 1995-09-21 Takehisa Matsuda Material to be worn on the eyeball
US5464667A (en) 1994-08-16 1995-11-07 Minnesota Mining And Manufacturing Company Jet plasma process and apparatus
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
BR9612119A (pt) 1995-12-07 1999-02-17 Bausch & Lomb Unidade monomérica composição de hidrogel lente de contato e método para produzir uma composição de hidrogel
US5714557A (en) 1995-12-07 1998-02-03 Bausch & Lomb Incorporated Monomeric units useful for reducing the modulus of low water polymeric silicone compositions
US5708094A (en) 1996-12-17 1998-01-13 Bausch & Lomb Incorporated Polybutadiene-based compositions for contact lenses
WO2002006373A1 (en) * 2000-07-17 2002-01-24 University Of Utah Research Foundation Hydrogel films and methods of making and using therefor
EP1539799B1 (en) 2002-06-21 2013-12-11 The University of Utah Research Foundation Crosslinked compounds and methods of making and using thereof
JP4537038B2 (ja) * 2003-11-14 2010-09-01 株式会社資生堂 架橋ゲルの製造方法
EP1694712A1 (en) 2003-12-04 2006-08-30 University of Utah Research Foundation Modified macromolecules and methods of making and using thereof
US7674781B2 (en) 2006-04-28 2010-03-09 Heather Sheardown Hyaluronic acid-retaining polymers
US20080141628A1 (en) 2006-12-15 2008-06-19 Bausch & Lomb Incorporated Packaging Solutions
US20080148689A1 (en) * 2006-12-20 2008-06-26 Bausch & Lomb Incorporated Packaging solutions
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
JP4869274B2 (ja) * 2008-03-21 2012-02-08 株式会社メニコン ソフトコンタクトレンズ包装製品及びソフトコンタクトレンズの包装方法
US8343942B2 (en) 2008-04-04 2013-01-01 University Of Utah Research Foundation Methods for treating interstitial cystitis
AU2009231634B2 (en) 2008-04-04 2014-05-15 University Of Utah Research Foundation Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof
US20100086512A1 (en) 2008-10-02 2010-04-08 Rolf Schaefer Mucomimetic compositions and uses therefore
US20100178317A1 (en) 2009-01-09 2010-07-15 Burke Susan E Lens Care Solutions with Hyaluronic Acid
IT1399351B1 (it) 2009-06-16 2013-04-16 Fidia Farmaceutici Procedimento per la sintesi di coniugati di glicosamminoglicani (gag) con molecole biologicamente attive, coniugati polimerici e usi relativi
US7994356B2 (en) 2009-07-09 2011-08-09 Bausch & Lomb Incorporated Mono ethylenically unsaturated polycarbosiloxane monomers
JP4981181B1 (ja) * 2011-03-22 2012-07-18 株式会社メニコン コンタクトレンズ用組成物
KR101303284B1 (ko) * 2011-04-06 2013-09-04 한국원자력연구원 히알루론산과 콘드로이틴 설페이트를 함유한 수화겔 및 이의 제조방법
KR20140022900A (ko) * 2011-04-22 2014-02-25 알콘 리서치, 리미티드 2종의 상이한 점도 증강제를 포함하는 점도 증강 시스템을 갖는 안과 조성물
EP3040348A1 (en) * 2014-12-29 2016-07-06 Galderma S.A. Graft copolymer
JP2017048296A (ja) * 2015-09-01 2017-03-09 日立化成株式会社 吸水性樹脂及びその製造方法

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5731298A (en) * 1992-01-03 1998-03-24 Reinmuller; Johannes Method for the treatment of scars and keloids
CN1075970A (zh) * 1992-02-05 1993-09-08 生化学工业株式会社 可光硫化的药糖氨基聚糖衍生物，交联葡糖氨基聚糖及其生产方法
EP2011816A1 (fr) * 2007-07-05 2009-01-07 Estelle Piron Gel co-réticulé de polysaccharides
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
CN101502675A (zh) * 2008-02-04 2009-08-12 山东省药学科学院 一种注射用含大分子水凝胶的透明质酸或其盐的混悬液及其制备方法
CN101721349A (zh) * 2008-10-16 2010-06-09 常州百瑞吉生物医药有限公司 可注射原位交联水凝胶及其制备方法和用途
CN104220078A (zh) * 2012-03-30 2014-12-17 菲迪亚医药公司 包括硫酸软骨素和透明质酸衍生物的药物制剂
CN102911380A (zh) * 2012-10-29 2013-02-06 北京爱美客生物科技有限公司 透明质酸与生物可降解高分子改性材料及制备方法
CN104225677A (zh) * 2013-06-13 2014-12-24 山东省生物药物研究院 交联透明质酸细胞支架材料及其制备方法和应用
US20170143870A1 (en) * 2014-04-01 2017-05-25 Merz Pharma Gmbh & Co. Kgaa Polysaccharide soft tissue fillers with improved persistence
EP3187510A1 (en) * 2015-12-29 2017-07-05 Galderma S.A. Carbohydrate crosslinker

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
徐新等: "交联透明质酸衍生物的制备进展", 《广东化工》 *
陈景华等: "制备透明质酸衍生物交联剂的应用研究", 《中国修复重建外科杂志》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115819983A (zh) * 2022-11-30 2023-03-21 中欧电子材料国际创新中心(合肥)有限公司 一种含八重氢键的交联型硅橡胶及其制备方法
CN115819983B (zh) * 2022-11-30 2023-09-22 中欧电子材料国际创新中心(合肥)有限公司 一种含八重氢键的交联型硅橡胶及其制备方法

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