CN113209033A - Rucaparib的高剂量强度片剂 - Google Patents
Rucaparib的高剂量强度片剂 Download PDFInfo
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- CN113209033A CN113209033A CN202110458329.2A CN202110458329A CN113209033A CN 113209033 A CN113209033 A CN 113209033A CN 202110458329 A CN202110458329 A CN 202110458329A CN 113209033 A CN113209033 A CN 113209033A
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- tablet
- azepine
- indol
- methylamino
- tetrahydro
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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| US62/101,739 | 2015-01-09 | ||
| CN201580042815.9A CN106794185A (zh) | 2014-08-22 | 2015-08-17 | Rucaparib的高剂量强度片剂 |
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| US12168004B2 (en) | 2014-02-05 | 2024-12-17 | Merck Sharp & Dohme Llc | Treatment of migraine |
| US11717515B2 (en) | 2020-12-22 | 2023-08-08 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| EP3182975B1 (en) * | 2014-08-22 | 2025-10-01 | pharma& Schweiz GmbH | High dosage strength tablets of rucaparib |
| CN106008530B (zh) * | 2016-07-24 | 2018-06-26 | 石家庄久正生物科技有限公司 | 一种抗卵巢癌药物Rucaparib关键中间体的制备方法 |
| CN108201534A (zh) * | 2016-12-16 | 2018-06-26 | 苏州苏融生物医药有限公司 | 一种瑞卡帕布口服缓控释药物组合物及其用途 |
| EP3573990B1 (en) | 2017-01-24 | 2024-07-10 | Assia Chemical Industries Ltd. | Solid state forms of rucaparib and of rucaparib salts |
| TWI761476B (zh) | 2017-03-27 | 2022-04-21 | 美商提薩羅有限公司 | 尼拉帕尼(niraparib)組合物 |
| SG11202002113TA (en) | 2017-09-26 | 2020-04-29 | Tesaro Inc | Niraparib formulations |
| WO2019130229A1 (en) | 2017-12-28 | 2019-07-04 | Mylan Laboratories Ltd | Methods and intermediates for preparing rucaparib |
| MA51524A (fr) | 2018-01-05 | 2020-11-11 | Cybrexa 1 Inc | Composés, compositions et méthodes pour le traitement de maladies impliquant des tissus malades acides ou hypoxiques |
| US12383545B1 (en) | 2018-06-08 | 2025-08-12 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| US12090148B2 (en) | 2020-07-29 | 2024-09-17 | Allergan Pharmaceuticals International Limited | Treatment of migraine |
| CN109111454A (zh) * | 2018-08-01 | 2019-01-01 | 宁波金未生物科技有限公司 | 一种瑞卡帕布s-樟脑磺酸盐 |
| CN108853030B (zh) * | 2018-09-26 | 2021-10-01 | 上海朝晖药业有限公司 | 一种治疗恶性肿瘤的药物制剂及其制备方法 |
| CN111542527A (zh) * | 2018-12-06 | 2020-08-14 | 上海诚妙医药科技有限公司 | 芦卡帕利樟脑磺酸盐的新晶型和制备方法及其用途 |
| PE20220485A1 (es) | 2019-07-10 | 2022-04-04 | Cybrexa 3 Inc | Conjugados peptidicos de agentes dirigidos a microtubulos como terapeuticos |
| PE20220563A1 (es) | 2019-07-10 | 2022-04-13 | Cybrexa 2 Inc | Conjugados peptidicos de citotoxinas como terapeuticos |
| WO2021220120A1 (en) | 2020-04-28 | 2021-11-04 | Rhizen Pharmaceuticals Ag | Novel compounds useful as poly(adp-ribose) polymerase (parp) inhibitors |
| EP4182318B1 (en) | 2020-07-14 | 2025-08-27 | Assia Chemical Industries Ltd. | Solid state forms of rucaparib salts |
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| EP4429636A1 (en) * | 2021-11-10 | 2024-09-18 | Crititech, Inc. | Rucaparib particles and uses thereof |
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| ATE454893T1 (de) | 2003-07-25 | 2010-01-15 | Cancer Rec Tech Ltd | Tricyclische parp-hemmer |
| AU2005286190A1 (en) | 2004-09-22 | 2006-03-30 | Cancer Research Technology Ltd. | Therapeutic combinations comprising poly(ADP-ribose) polymerases inhibitor |
| ATE551345T1 (de) | 2004-09-22 | 2012-04-15 | Pfizer | Polymorphe formen des phosphatsalzes von 8-fluor- 2-ä4-ä(methylamino)methylüphenylü-1,3,4,5- tetrahydro-6h-azepinoä5,4,3-cdüindol-6-on |
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| US20110136883A1 (en) * | 2008-04-09 | 2011-06-09 | Lek Pharmaceuticals D.D. | Granulation of active pharmaceutical ingredients |
| PT2534153T (pt) * | 2010-02-12 | 2016-12-27 | Pfizer | Sais e polimorfos de 8-fluoro-2-{4-[(metilamino}metil]fenil}-1,3,4,5-tetrahidro-6h-azepino[5,4,3-cd]indol-6-ona |
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