CN113143804A - Plant composition and application thereof - Google Patents

Plant composition and application thereof Download PDF

Info

Publication number
CN113143804A
CN113143804A CN202110470778.9A CN202110470778A CN113143804A CN 113143804 A CN113143804 A CN 113143804A CN 202110470778 A CN202110470778 A CN 202110470778A CN 113143804 A CN113143804 A CN 113143804A
Authority
CN
China
Prior art keywords
parts
oil
mosquito
itching
relieving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202110470778.9A
Other languages
Chinese (zh)
Other versions
CN113143804B (en
Inventor
刘前忠
王鹏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangzhou Yizhuang Biotechnology Co ltd
Original Assignee
Guangzhou Yizhuang Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangzhou Yizhuang Biotechnology Co ltd filed Critical Guangzhou Yizhuang Biotechnology Co ltd
Priority to CN202110470778.9A priority Critical patent/CN113143804B/en
Publication of CN113143804A publication Critical patent/CN113143804A/en
Application granted granted Critical
Publication of CN113143804B publication Critical patent/CN113143804B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a plant composition, and relates to the technical field of daily necessities. The plant composition comprises the following components in parts by weight: 0.1-5 parts of lavender oil, 0.1-3 parts of citronella oil, 0.1-3 parts of argy wormwood leaf oil, 0.1-10 parts of lithospermum oil, 0.1-3 parts of rosemary leaf oil and 0.1-3 parts of bisabolol. The invention also provides the mosquito-repellent itching-relieving paste, and the proportion of oil to wax is reasonably set, so that the mosquito-repellent itching-relieving paste passes a strict high-low temperature stability test experiment, has very good bright appearance, is quick in product forming and pasting, and is not influenced by climate temperature, seasons and the like.

Description

Plant composition and application thereof
Technical Field
The invention relates to the technical field of daily necessities, in particular to a plant composition and application thereof.
Background
In spring and summer, when mosquitoes breed vigorously, the mosquitoes are easy to bite in daily life, skin itch and stabbing pain are caused, the skin biting part is increased continuously, and the skin is broken and ulcerated due to factors such as friction or hand grasping. People have stronger requirements on mosquito prevention and itching relief. Along with the popularization of scientific knowledge, people have mild requirements on mosquito-proof products, and the mosquito-proof products are nontoxic and low-irritation mild products, so that the mosquito-proof and itching-relieving effects are achieved.
In the itching relieving balm, cooling agents such as menthol, borneol, menthyl lactate and the like are mostly used to provide immediate cooling stimulation to the skin to achieve a transient itching relieving effect, but the menthol, the borneol and the like have relatively high volatility, strong and short cooling effect and poor itching relieving effect. On the other hand, the cool feeling agent has large irritation, easily causes skin problems such as irritation, allergy, inflammation and the like to human skin, and meanwhile, the cool feeling agent has large addition amount, has relatively pungent smell, and easily causes irritation to respiratory tracts of human bodies, especially infants and children.
Most of the itching relieving balms are ointment system products, the stability of the ointment products is greatly influenced by temperature seasons, the ointment products are stored in places with high temperature, and the phenomena of softening, oil production, thinning and the like are easy to occur in the products. The product is stored in a place with lower temperature, the product is easy to harden, the material body is not easy to take, and the use experience is reduced.
Disclosure of Invention
Based on the above, the invention aims to overcome the defects of the prior art and provide the plant composition which has the effects of inhibiting bacteria, diminishing inflammation, repairing allergy, sterilizing, relieving itching, preventing and treating mosquito bites, emits light and natural smell and does not cause irritation to respiratory tracts.
In order to achieve the purpose, the technical scheme adopted by the invention is as follows: a plant composition comprises the following components in parts by weight: 0.1-5 parts of lavender oil, 0.1-3 parts of citronella oil, 0.1-3 parts of argy wormwood leaf oil, 0.1-10 parts of lithospermum oil, 0.1-3 parts of rosemary leaf oil and 0.1-3 parts of bisabolol.
Lavender oil as a fragrance, as an antibacterial and insect repellent, to improve the barrier function of the skin, as an anti-inflammatory and as a moisturizer; the blumea oil has an inhibiting effect on the portable activation of nuclear factors, which shows that the blumea oil has anti-inflammation, can promote the synthesis of collagen, has oxidation resistance, can be used for skin-activating cosmetics, has broad-spectrum antibacterial property and has an antibacterial effect; the citronella oil has faint scent, and has antibacterial and antioxidant effects, so that the skin is clear and moist; the arnebia oil has anti-inflammatory effect, can promote the activity of cathepsin, and can enhance the metabolism of skin cells; the rosemary leaf oil has the activities of sterilization, disinsection, inflammation diminishing and the like, has strong killing power to mosquitoes, has the inhibition effect on elastase and collagenase, has the skin activating effect, and also has certain anti-inflammatory and astringent effects; the bisabolol has the functions of anti-allergy, anti-irritation and auxiliary synergism.
The plant composition provided by the invention has the effects of inhibiting bacteria, diminishing inflammation, repairing allergy, sterilizing, relieving itching, preventing and treating mosquito bites, and simultaneously has a light and natural smell without stimulating respiratory tracts by reasonable proportioning.
Preferably, the plant composition comprises the following components in parts by weight: 0.3-3 parts of lavender oil, 0.3-2.5 parts of citronella oil, 0.3-2.5 parts of blumea oil, 0.5-5 parts of lithospermum oil, 0.2-2 parts of rosemary leaf oil and 0.3-2.5 parts of bisabolol.
According to the invention, the lavender oil, the citronella oil, the blumea oil, the lithospermum oil, the rosemary leaf oil and the bisabolol are combined to obtain the plant composition, and the plant composition has good effects of inhibiting bacteria, diminishing inflammation, repairing allergy, sterilizing and relieving itching after being compounded, and has excellent effects of preventing and treating mosquito bites. Meanwhile, the emitted light natural smell is lasting and natural.
Preferably, the plant composition comprises the following components in parts by weight: 0.3-1.5 parts of lavender oil, 0.3-1.5 parts of citronella oil, 0.3-2 parts of blumea oil, 1-3 parts of lithospermum oil, 0.3-1.5 parts of rosemary leaf oil and 0.3-2 parts of bisabolol.
In the plant composition, the proportion of the components can influence the influence, and researches show that the mosquito-repelling and itching-relieving ointment has better mosquito-repelling and itching-relieving effects within the preferable range.
In addition, the invention also provides application of the plant composition in mosquito repellent products.
Furthermore, the invention also provides a mosquito-repellent itching-relieving ointment containing the plant composition.
Preferably, the mosquito-repellent itching-relieving paste also comprises the following components in parts by weight: 30-70 parts of mineral oil, 2-15 parts of polyisobutylene, 1-30 parts of microcrystalline wax, 1-10 parts of polyethylene, 1-10 parts of beeswax, 5-40 parts of cocoa seed fat, 0.5-10 parts of ozokerite, 0.5-5 parts of antioxidant and 0.01-0.5 part of preservative.
Polyisobutylene is a saturated linear polymer used as a binder in cosmetics; the microcrystalline wax is a safe component and additive, is used as an adhesive and an emulsion stabilizer in cosmetics, has excellent elasticity and viscosity, and is a soft wax which can reduce oily feeling and greasiness when being applied, increase the melting point of the paste and improve the heat-resistant stability of the product; the polyethylene is odorless and nontoxic, feels like wax, has excellent low-temperature resistance, can keep soft at low temperature, and has high melting point, so that the heat-resistant stability of the product can be improved; the cocoa seed ester is excellent oil in cosmetics, can nourish skin, has good permeability, can promote skin metabolism, has the effect of resisting aging by combining the oxidation resistance of the cocoa seed ester, and has the effects of resisting allergy and relieving by inhibiting histamine release; the ceresin wax is used as an antistatic agent and an adhesive in cosmetics, belongs to natural mineral wax, has the characteristics of high melting point and hard molding, can endow a product with certain hardness, and improves the heat-resistant stability of the product;
preferably, the mosquito-repellent itching-relieving paste comprises the following components in parts by weight: 35-60 parts of mineral oil, 3-13 parts of polyisobutylene, 5-25 parts of microcrystalline wax, 2-8 parts of polyethylene, 2-8 parts of beeswax, 10-30 parts of cocoa seed fat, 1-8 parts of ozokerite, 1-3 parts of antioxidant and 0.05-0.3 part of preservative.
Preferably, the mosquito-repellent itching-relieving paste comprises the following components in parts by weight: 40-55 parts of mineral oil, 4-10 parts of polyisobutylene, 10-20 parts of microcrystalline wax, 3-7 parts of polyethylene, 3-6 parts of beeswax, 15-25 parts of cocoa seed fat, 2-5 parts of ozokerite, 1-2 parts of antioxidant and 0.05-0.15 part of preservative.
Preferably, the mineral oil is at least one of 5# white oil, 7# white oil, 9# white oil, 15# white oil and 26# white oil, the beeswax is at least one of white beeswax and synthetic beeswax, the antioxidant is at least one of vitamin E, butylated hydroxytoluene, tocopherol acetate and butylated hydroxyanisole, and the preservative is at least one of propyl hydroxybenzoate, methyl hydroxybenzoate, phenoxyethanol and benzyl alcohol.
Mineral oil is used as emollient in cosmetics, is colorless and tasteless, has high hypoallergenic safety degree, and has antistatic effect; meanwhile, the mineral oil has a sealing effect, a protective film can be formed on the surface of the skin, the loss of skin moisture is protected, the volatility of components in the formula is reduced, and the effect is exerted to a greater extent; the beeswax belongs to animal wax, is used as a softening agent in cosmetics, has the functions of nourishing and softening skin, and increases the viscosity and the durability of the product; the antioxidant can protect the vegetable oil in the formula and prevent or delay the rancidity of the oil.
In addition, the invention also provides a preparation method of the mosquito-repellent itching-relieving paste, which comprises the following steps:
(1) mixing mineral oil, polyisobutylene, microcrystalline wax, polyethylene, beeswax, ceresin and cacao seed fat, stirring, and heating until the solid is completely dissolved to obtain a mixed solution A;
(2) and (2) cooling the mixed liquor A obtained in the step (1), sequentially adding an antioxidant, a preservative and a plant composition, and stirring for 20-30min to prepare the mosquito-repelling itching-relieving paste.
Preferably, in the step (1), the heating temperature is 85-95 ℃, and the stirring time is 20-30 min.
Preferably, in the step (2), the temperature of the mixed solution A is reduced to 60-70 ℃, the mosquito-repelling itching-relieving ointment is prepared, then sampling and detecting are carried out, and filling is carried out after the mosquito-repelling itching-relieving ointment is qualified.
Compared with the prior art, the invention has the beneficial effects that:
(1) the plant composition provided by the invention has the effects of inhibiting bacteria, diminishing inflammation, repairing and resisting allergy, sterilizing and relieving itching, and preventing and treating mosquito bites, and meanwhile, the emitted smell is light and natural, and the respiratory tract cannot be stimulated.
(2) Meanwhile, the mosquito-repelling itching-relieving cream provided by the invention has the advantages that the proportion of oil to wax is set, so that the product passes a strict high-low temperature stability test experiment, the appearance is very bright, the product is quickly molded and forms cream, and the cream is not influenced by climate temperature, seasons and the like.
Detailed Description
To better illustrate the objects, aspects and advantages of the present invention, the present invention will be further described with reference to specific examples.
The present application sets forth the components and parts by weight selections for the plant compositions of examples 1-6, specific examples 1-6 as shown in table 1, and the components and parts by weight selections for the other components of specific examples 1-6 as shown in table 2:
TABLE 1 selection of components and parts by weight of the botanical compositions of examples 1-6
Figure BDA0003044792490000041
Figure BDA0003044792490000051
Table 2 component and part by weight selection of other components of examples 1-6
Other Components Example 1 Example 2 Example 3 Example 4 Example 5 Example 6
Mineral oil 30 70 35 60 40 55
Polyisobutenes 15 2 3 13 4 10
Microcrystalline wax 30 1 5 25 10 20
Polyethylene 10 1 2 8 7 3
Beeswax (Cera flava) 1 10 2 8 3 6
Cocoa seed butter 5 40 10 30 25 15
Earth wax 10 0.5 1 8 2 5
Antioxidant agent 0.5 5 1 3 1 2
Preservative 0.01 0.5 0.05 0.3 0.05 0.15
Examples 1 to 6 the mosquito repellent antipruritic cream is prepared by weighing the components in the parts by weight shown in tables 1 and 2 as follows: (1) mixing mineral oil, polyisobutylene, microcrystalline wax, polyethylene, beeswax, ceresin and cacao seed fat, stirring, and heating until the solid is completely dissolved to obtain a mixed solution A;
(2) and (2) cooling the mixed liquor A obtained in the step (1), sequentially adding an antioxidant, a preservative and a plant composition, and stirring for 20-30min to prepare the mosquito-repelling itching-relieving paste.
Meanwhile, the present application sets comparative examples 1 to 8, components and parts by weight of the plant composition in comparative examples 1 to 7 are shown in table 3, and the remaining components and parts by weight, and preparation method are exactly the same as example 5. Comparative example 8 is the itching relieving ointment of Rana Nigromaculata semen for children.
TABLE 3 selection of Components and parts by weight of comparative examples 1-7 botanical compositions
Figure BDA0003044792490000061
Test example 1 antipruritic effect test
Test subjects: 30 volunteers (male-15, female-15) with normal skin status of 18-25 years old
The test process comprises the following steps: selecting 6 parts of left and right hands for histamine spot-coating test
Test determination parameters: (1) degree of redness and swelling of skin: visual scoring; (2) itch feeling: subjective sensory test results of the subjects
The results of the antipruritic effect test for examples and comparative examples are shown in tables 4 and 5:
table 4 test results of antipruritic effect of examples
Figure BDA0003044792490000062
Figure BDA0003044792490000071
TABLE 5 results of the antipruritic effect test of comparative examples
Figure BDA0003044792490000072
As can be seen from Table 4, the itching relieving balms provided by the embodiment of the invention have good itching relieving effect, and can achieve the itching relieving effect within 9 minutes, while the comparative example 8 is the common Rana chensinensis children lithospermum itching relieving balm on the market, and the itching relieving effect is 27 minutes, and the itching relieving effect provided by the embodiment is obviously superior to that of the comparative example 8.
The itching relieving balsam provided by the comparative example 7 has the itching relieving time of 18min, only 5 plant compositions are contained in the comparative examples 1 to 3, only 4 plant compositions are contained in the comparative examples 4 to 6, the lavender oil, the citronella oil and the argy wormwood oil in the plant compositions are not contained in the comparative example 7, and only 3 plant compositions are contained in the comparative example 7, so that the itching relieving effect is greatly reduced, and the synergistic effect of the lavender oil, the citronella oil and the argy wormwood oil in the plant compositions is shown.
The results of the tests for the antibacterial and anti-inflammatory effects of the examples and comparative examples are shown in tables 6 and 7:
TABLE 6 test results of the antibacterial and anti-inflammatory effects of the examples
Figure BDA0003044792490000073
TABLE 7 test results of antibacterial and anti-inflammatory effects of comparative examples
Figure BDA0003044792490000074
Figure BDA0003044792490000081
Table 6 shows that the itching relieving balm provided by the embodiment of the present invention has good antibacterial and anti-inflammatory effects, and can achieve the antibacterial and anti-inflammatory effects within 8 minutes, while the comparative example 8 is a common rana japonica and prince children lithospermum itching relieving balm on the market, and the antibacterial and anti-inflammatory effects are achieved for 25 minutes, and the antibacterial and anti-inflammatory effects provided by the embodiment are significantly better than the comparative example 8.
The itching relieving balm provided by the comparative example 7 has the average time for skin redness to subside of 17min, the comparative example 7 does not contain the lavender oil, the citronella oil and the blumea oil in the plant composition, only contains 3 of the plant compositions, and the average time for skin redness to subside is obviously increased, which shows that the lavender oil, the citronella oil and the blumea oil in the plant composition have a synergistic effect. The average time value for eliminating the skin redness is 11-12min in comparative examples 1-3, and the average time value for eliminating the skin redness is 13-15min in comparative examples 4-6, which shows that the plant composition provided by the invention is applied to the itching relieving balm, and the components are matched with each other, so that good effects of eliminating redness, resisting bacteria and diminishing inflammation are achieved.
Test example 2 stability test
Test objects: example balm and comparative example balm
The testing process comprises the following steps: 1. the refrigerator is adjusted to-15 ℃, two samples are taken respectively, one sample is placed in the refrigerator and kept for 24 hours, then the sample is taken out, the room temperature is recovered, the sample is compared with the other sample, and whether phenomena such as thinning, color change, layering, hardness change and the like exist or not is observed, so that the cold resistance of the product is judged. 2. The method comprises the steps of firstly adjusting an electric heating constant-temperature incubator to 52 ℃, then respectively taking two samples, placing one sample in the electric heating constant-temperature incubator for 24 hours, taking out the sample, recovering the room temperature, then comparing the sample with the other sample, and observing whether the sample has phenomena of thinning, color change, layering, hardness change and the like so as to judge the heat resistance of the product.
Testing parameters: testing the appearance change state of the sample after cold and heat resistance
The invention is provided with comparative examples 9-11, the components, the parts by weight and the preparation method of the plant composition in the comparative examples 9-11 are completely the same as the example 5, and the components and the parts by weight of the comparative examples 9-11 are shown in the table 8:
TABLE 8 selection of Components and parts by weight for comparative examples 9-11
Other Components Comparative example 9 Comparative example 10 Comparative example 11 Comparative example 12 Comparative example 13 Comparative example 14
Mineral oil 40 40 40 40 40 40
Polyisobutenes 4 4 4
Microcrystalline wax 10 10
Polyethylene 5 5
Beeswax (Cera flava) 3 3 3
Cocoa seed butter 25 25 25 25 25 50
Earth wax 5 5 5 5
Antioxidant agent 0.5 5 1 3 1 2
Preservative 0.01 0.5 0.05 0.3 0.05 0.15
The results of the stability tests of the examples and comparative examples are shown in tables 9 and 10:
table 9 example stability test results
Figure BDA0003044792490000091
Table 10 comparative example stability test results
Figure BDA0003044792490000092
Figure BDA0003044792490000101
As can be seen from Table 8, the antipruritic balms provided by the examples of the invention all have better stability test results, and the stability provided by the examples is obviously better than that of the comparative examples. Therefore, the microcrystalline wax, the polyethylene and the ozokerite which are reasonably matched in proportion are very important to the stability of the paste, and the stability is not essential.
Finally, it should be noted that the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting the protection scope of the present invention, and although the present invention is described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions can be made on the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention.

Claims (10)

1. The plant composition is characterized by comprising the following components in parts by weight: 0.1-5 parts of lavender oil, 0.1-3 parts of citronella oil, 0.1-3 parts of argy wormwood leaf oil, 0.1-10 parts of lithospermum oil, 0.1-3 parts of rosemary leaf oil and 0.1-3 parts of bisabolol.
2. The plant composition of claim 1, comprising the following components in parts by weight: 0.3-3 parts of lavender oil, 0.3-2.5 parts of citronella oil, 0.3-2.5 parts of blumea oil, 0.5-5 parts of lithospermum oil, 0.2-2 parts of rosemary leaf oil and 0.3-2.5 parts of bisabolol.
3. The plant composition of claim 2, comprising the following components in parts by weight: 0.3-1.5 parts of lavender oil, 0.3-1.5 parts of citronella oil, 0.3-2 parts of blumea oil, 1-3 parts of lithospermum oil, 0.3-1.5 parts of rosemary leaf oil and 0.3-2 parts of bisabolol.
4. Use of a plant composition according to any one of claims 1 to 3 in mosquito repellent products.
5. A mosquito-repellent itching-relieving ointment characterized by comprising the plant composition according to any one of claims 1 to 3.
6. A mosquito-repelling itching-relieving cream as claimed in claim 5, further comprising the following components in parts by weight: 30-70 parts of mineral oil, 2-15 parts of polyisobutylene, 1-30 parts of microcrystalline wax, 1-10 parts of polyethylene, 1-10 parts of beeswax, 5-40 parts of cocoa seed fat, 0.5-10 parts of ozokerite, 0.5-5 parts of antioxidant and 0.01-0.5 part of preservative.
7. A mosquito-repelling itching-relieving cream as claimed in claim 6, which comprises the following components in parts by weight: 35-60 parts of mineral oil, 3-13 parts of polyisobutylene, 5-25 parts of microcrystalline wax, 2-8 parts of polyethylene, 2-8 parts of beeswax, 10-30 parts of cocoa seed fat, 1-8 parts of ozokerite, 1-3 parts of antioxidant and 0.05-0.3 part of preservative.
8. A mosquito-repelling itching-relieving cream as claimed in claim 7, which comprises the following components in parts by weight: 40-55 parts of mineral oil, 4-10 parts of polyisobutylene, 10-20 parts of microcrystalline wax, 3-7 parts of polyethylene, 3-6 parts of beeswax, 15-25 parts of cocoa seed fat, 2-5 parts of ozokerite, 1-2 parts of antioxidant and 0.05-0.15 part of preservative.
9. A mosquito-repellent itching-relieving cream according to any one of claims 6 to 8, wherein the mineral oil is at least one of 5# white oil, 7# white oil, 9# white oil, 15# white oil and 26# white oil, the beeswax is at least one of white beeswax and synthetic beeswax, the antioxidant is at least one of vitamin E, butylated hydroxytoluene, tocopherol acetate and butylated hydroxyanisole, and the preservative is at least one of propylparaben, methylparaben, phenoxyethanol and benzyl alcohol.
10. A method for preparing a mosquito-repellent itching-relieving ointment as claimed in any one of claims 6 to 8, which comprises the following steps:
(1) mixing mineral oil, polyisobutylene, microcrystalline wax, polyethylene, beeswax, ceresin and cacao seed fat, stirring, and heating until the solid is completely dissolved to obtain a mixed solution A;
(2) and (2) cooling the mixed liquor A obtained in the step (1), sequentially adding an antioxidant, a preservative and a plant composition, and stirring for 20-30min to prepare the mosquito-repelling itching-relieving paste.
CN202110470778.9A 2021-04-28 2021-04-28 Plant composition and application thereof Active CN113143804B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110470778.9A CN113143804B (en) 2021-04-28 2021-04-28 Plant composition and application thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110470778.9A CN113143804B (en) 2021-04-28 2021-04-28 Plant composition and application thereof

Publications (2)

Publication Number Publication Date
CN113143804A true CN113143804A (en) 2021-07-23
CN113143804B CN113143804B (en) 2023-02-03

Family

ID=76872365

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110470778.9A Active CN113143804B (en) 2021-04-28 2021-04-28 Plant composition and application thereof

Country Status (1)

Country Link
CN (1) CN113143804B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116098839A (en) * 2023-04-11 2023-05-12 广州品赫化妆品有限公司 Oil-soluble composition with relieving itching function and preparation method thereof

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007084240A2 (en) * 2006-01-19 2007-07-26 Ziva International Anti-itch stick and method of use
CN103169639A (en) * 2013-04-02 2013-06-26 蚌埠天泽家用化学品有限公司 Natural plant mosquito-repellent liquid
CN103462834A (en) * 2013-08-16 2013-12-25 许春晖 Room-temperature volatile natural plant essential oil mosquito repelling gel
CN105288291A (en) * 2015-11-25 2016-02-03 福建春辉生物工程有限公司 Wild tea oil-containing universal Lithospermum erythrorhizon ointment
CN105476892A (en) * 2014-09-17 2016-04-13 福建省梦娇兰日用化学品有限公司 Multi-effect skin moisturizing cream containing lithospermum erythrorhizon and other vegetable oils, and preparation method thereof
CN107349170A (en) * 2017-07-13 2017-11-17 广州暨南生物医药研究开发基地有限公司 A kind of mugwort mosquito repellant antipruritus toilet water and preparation method thereof
CN108420771A (en) * 2018-06-08 2018-08-21 康柏利科技(苏州)有限公司 A kind of zicao soft plaster and preparation method thereof
CN109260054A (en) * 2018-10-23 2019-01-25 广州艾蓓生物科技有限公司 A kind of plant mosquito-repellent antipruritic cream and preparation method thereof
CN110354047A (en) * 2019-08-27 2019-10-22 清远市族原生物科技有限公司 A kind of compound draft zicao soft plaster and preparation method thereof
CN110897956A (en) * 2019-12-14 2020-03-24 康柏利科技(苏州)有限公司 Lithospermum erythrorhizon ointment containing phytosterol and preparation method thereof
CN112353931A (en) * 2020-11-25 2021-02-12 广州旭升化工科技有限公司 Chinese herbal medicine compound ointment for soothing skin of infants and preparation method thereof

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007084240A2 (en) * 2006-01-19 2007-07-26 Ziva International Anti-itch stick and method of use
CN103169639A (en) * 2013-04-02 2013-06-26 蚌埠天泽家用化学品有限公司 Natural plant mosquito-repellent liquid
CN103462834A (en) * 2013-08-16 2013-12-25 许春晖 Room-temperature volatile natural plant essential oil mosquito repelling gel
CN105476892A (en) * 2014-09-17 2016-04-13 福建省梦娇兰日用化学品有限公司 Multi-effect skin moisturizing cream containing lithospermum erythrorhizon and other vegetable oils, and preparation method thereof
CN105288291A (en) * 2015-11-25 2016-02-03 福建春辉生物工程有限公司 Wild tea oil-containing universal Lithospermum erythrorhizon ointment
CN107349170A (en) * 2017-07-13 2017-11-17 广州暨南生物医药研究开发基地有限公司 A kind of mugwort mosquito repellant antipruritus toilet water and preparation method thereof
CN108420771A (en) * 2018-06-08 2018-08-21 康柏利科技(苏州)有限公司 A kind of zicao soft plaster and preparation method thereof
CN109260054A (en) * 2018-10-23 2019-01-25 广州艾蓓生物科技有限公司 A kind of plant mosquito-repellent antipruritic cream and preparation method thereof
CN110354047A (en) * 2019-08-27 2019-10-22 清远市族原生物科技有限公司 A kind of compound draft zicao soft plaster and preparation method thereof
CN110897956A (en) * 2019-12-14 2020-03-24 康柏利科技(苏州)有限公司 Lithospermum erythrorhizon ointment containing phytosterol and preparation method thereof
CN112353931A (en) * 2020-11-25 2021-02-12 广州旭升化工科技有限公司 Chinese herbal medicine compound ointment for soothing skin of infants and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
电子凭证-国产非特殊用途化妆品备案信息服务平台: "柏纷香茅紫草驱护霜", 《FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=20151228162015IXSR4&NID=20151228162015IXSR4》 *
电子凭证-国产非特殊用途化妆品备案信息服务平台: "麦蒲花MAIPUHUA香草膏", 《FTBA.NMPA.GOV.CN:8181/FTBAN/ITOWNET/HZP_BA/FW/PZ.JSP?PROCESSID=202103201635346RPXF&NID=202103201635346RPXF》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116098839A (en) * 2023-04-11 2023-05-12 广州品赫化妆品有限公司 Oil-soluble composition with relieving itching function and preparation method thereof
CN116098839B (en) * 2023-04-11 2023-07-07 广州品赫化妆品有限公司 Oil-soluble composition with relieving itching function and preparation method thereof

Also Published As

Publication number Publication date
CN113143804B (en) 2023-02-03

Similar Documents

Publication Publication Date Title
EP0060553B1 (en) Preparation for treating outer skin wounds and process for manufacturing said preparation
EP2744474B1 (en) Medicinal skin protection composition with an active ingredient combination which improves the skin barrier
US10624837B2 (en) Food-grade lip balm and preparation method thereof
CN102836351B (en) Skin care essential balm for relieving itching and diminishing swelling and preparation method thereof
US7029711B2 (en) Mixture of and method of making a trancutaneous pain relief composition
CN105853260B (en) A kind of diaper dermatitis frost and preparation method thereof
CN109260054B (en) Plant anti-mosquito itching-relieving cream and preparation method thereof
CN109925207A (en) A kind of new food preservative composition and its preparation method and application
CN110897956A (en) Lithospermum erythrorhizon ointment containing phytosterol and preparation method thereof
CN113143804B (en) Plant composition and application thereof
CN114099387B (en) Rose whitening and moisturizing essence emulsion and preparation method thereof
KR20190001530A (en) Composition for relieving and improving atopic dermatitis
US20040101577A1 (en) Composition for treating acne vulgaris and fabrication method
CN110279626A (en) With the cosmetic composition and preparation method thereof for cooperateing with long-acting moistening effect
CN113398043A (en) Composite hermetia illucens oil composition and application thereof
CN105125457A (en) Multifunction lipstick containing natural constituents and making method thereof
KR20150106244A (en) UV protection and moisturizing cosmetic composition
CN111214397A (en) Plant skin moistening composition, preparation method thereof and lip balm
CN112057400B (en) Antiperspirant and preparation method thereof
KR20190075405A (en) Cosmetic composition including beeswax with animal oil and vegetable oil
US20200222305A1 (en) Natural skin care composition
CN111329806A (en) Allergy-relieving repair anti-inflammatory composition and preparation method thereof
CN104587279A (en) Oil-in-water type menthol ointment and preparation method thereof
KR101326679B1 (en) Skin external composition for treating or alleviating diaper rash containing zinc oxide stabilized by polyglyceryl-2 dipolyhydroxystearate
CN116098839B (en) Oil-soluble composition with relieving itching function and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant