CN113133963A - Skin care product, preparation method thereof and application thereof in skin line fading - Google Patents

Skin care product, preparation method thereof and application thereof in skin line fading Download PDF

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Publication number
CN113133963A
CN113133963A CN202110488774.3A CN202110488774A CN113133963A CN 113133963 A CN113133963 A CN 113133963A CN 202110488774 A CN202110488774 A CN 202110488774A CN 113133963 A CN113133963 A CN 113133963A
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skin care
extract
care product
skin
mixing
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Inventor
王娟
裴运林
聂艳峰
郭朝万
胡露
蒲艳
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Guangdong Marubi Biological Technology Co Ltd
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Guangdong Marubi Biological Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The application relates to the field of skin care products, in particular to a skin care product, a preparation method thereof and application thereof in skin line fading. The skin care product mainly comprises the following components: bisabolol, ginger root extract, chamomile oil, bitter orange flower oil, and small fruit coffee seed extract. The skin care product provided by the embodiment of the application has the effect of effectively lightening wrinkles, can effectively lock the moisture of the skin, and has the effect of weakening fine wrinkles to different degrees on the grain of the skin, the raised line and the corner lines.

Description

Skin care product, preparation method thereof and application thereof in skin line fading
Technical Field
The application relates to the field of skin care products, in particular to a skin care product, a preparation method thereof and application thereof in skin line fading.
Background
With the increasing pursuit of skin health and skin beauty, functional skin care products become the first choice for people to select skin care products, such as whitening skin care products, moisturizing skin care products, anti-wrinkle skin care products, antioxidant skin care products and the like.
The application aims to provide a skin care product with a wrinkle reducing effect.
Disclosure of Invention
The embodiment of the application aims to provide a skin care product, a preparation method thereof and application of the skin care product in skin line fading, and aims to provide the skin care product with a line fading effect.
The application provides a skin care product which mainly comprises the following components in percentage by mass:
0.01-1% of bisabolol, 0.01-1% of ginger root extract, 0.001-0.05% of mother chrysanthemum oil, 0.001-0.05% of bitter orange flower oil and 0.01-2% of small fruit coffee seed extract.
The skin care product provided by the embodiment of the application has the effect of effectively lightening wrinkles, can effectively lock the moisture of the skin, and has the effect of weakening fine wrinkles to different degrees on the grain of the skin, the raised line and the corner lines.
The application also provides a preparation method of the skin care product, which comprises the following steps:
montanov L, squalane, octyl methicone, DUB CIRE H1, batyl alcohol, hydrogenated lecithin, ubiquinone, behenyl alcohol, dimethicone, and tocopheryl acetate.
NATRULON H-6, glyceryl polyether-26, TR-1, sodium hyaluronate, dipotassium glycyrrhizinate, allantoin, disodium EDTA and water.
Mixing the water phase and the oil phase, adding the rest raw materials, and uniformly mixing.
The skin care product prepared by the preparation method has a good wrinkle-reducing effect; the preparation method is simple, harsh experimental conditions are not needed in the preparation process, and the equipment cost is low.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions of the embodiments of the present application will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.
The skin care product, the preparation method thereof and the application thereof in lightening skin lines in the embodiments of the present application are specifically described below.
A skin care product mainly comprises the following components:
0.01-1% of bisabolol, 0.01-1% of ginger root extract, 0.001-0.05% of mother chrysanthemum oil, 0.001-0.05% of bitter orange flower oil and 0.01-2% of small fruit coffee seed extract.
A skin care product containing bisabolol, rhizoma Zingiberis recens extract, flos Matricariae Chamomillae oil, bitter orange flower oil and small fruit coffee seed extract as main effective components has wrinkle removing effect.
In some embodiments of the present application, the percentage of each component to the total mass of the skin care product is as follows:
the bisabolol may be 0.01 to 1%, for example, 0.01%, 0.04%, 0.09%, 0.1%, 0.17%, 0.24%, 0.35%, 0.43%, 0.5%, 1%.
The ginger root extract is 0.01-1%, such as 0.01%, 0.02%, 0.08%, 0.1%, 0.18%, 0.25%, 0.34%, 0.45%, 0.5%, 1%.
The content of the chamomile oil is 0.001-0.05%, and can be, for example, 0.001%, 0.005%, 0.07%, 0.01%, 0.019%, 0.026%, 0.033%, 0.042%, 0.05%.
0.001-0.05% of neroli oil, for example, 0.001%, 0.003%, 0.007%, 0.01%, 0.018%, 0.027%, 0.035%, 0.047%, 0.05%.
The extract of coffee cherokee seed can be 0.01-2%, for example, 0.01%, 0.03%, 0.09%, 0.1%, 0.15%, 0.25%, 0.35%, 0.44%, 0.5%, 1%, 2%.
Illustratively, the bisabolol, ginger (ZINGIBER OFFICINALE) root extract is SymRelief100 available from osxue corporation.
Matricaria CHAMOMILLA (CHAMOMILLA RECUTITA) flower oil was purchased from Feycol.
Bitter orange (CITRUS AURANTIUM AMARA) flower oil, available from wilfine corporation.
Coffea ARABICA (Coffea ARABICA) seed extract was purchased from BioGenic CellLite-220 of Vigorean.
In some embodiments, the skin care product of the present application further comprises a distiller's grains extract, and the distiller's grains extract is mixed with the rest of the components to promote the skin care product to have the effect of reducing wrinkles.
In some embodiments of the present application, the skin care product of the embodiments of the present application mainly comprises the following components in percentage by mass:
1-3% Montanov L, 1-3% squalane, 2-4% octyl methicone, 0.5-2% DUB CIRE H1, 0.1-0.5% batyl alcohol, 0.3-1% hydrogenated lecithin, 0.01-0.05% ubiquinone, 0.3-1% behenyl alcohol, 0.5-1.5% polydimethylsiloxane, 0.1-0.5% tocopheryl acetate, 2-5% NATRULON H-6, 2-5% glyceryl polyether-26, 0.1-0.3% TR-1, 0.05-0.2% sodium hyaluronate, 0.01-0.2% dipotassium glycyrrhizinate, 0.1-0.5% allantoin, 0.01-0.2% EDTA-2 Na, 0.5-1% SELUS, 0.06-0.18% PC, 0.3-0.5% Symphosol, 0.5-5% allantoin, 0.01-0.2% DAGY-2% alcohol extract, 0.5-5% alcohol extract, 0.05-5% alcohol extract, 0.1-1% of DECORYL peptide solution C, 1-4% of Argiline Amplified peptide solution, 0.5-3% of ZPC-019S, 0.01-0.5% of bisabolol, 0.01-0.5% of ginger root extract, 0.001-0.01% of chamomile oil, 0.001-0.01% of bitter orange flower oil, 0.01-1% of small fruit coffee seed extract and the balance of water.
The proportions and sources of the various raw materials in the skin care products of the present application are exemplified below.
The content of Montanov L is 1 to 3%, and may be, for example, 1%, 1.2%, 1.8%, 2%, 2.3%, 3%; montanov L contains C14-22 alcohol, C12-20 alkyl glucoside, water, glucose, etc., which are available from Baihabo corporation.
The squalane content is 1 to 3%, and may be, for example, 1%, 1.3%, 1.9%, 2.1%, 2.3%, 2.8%, 3%; SQUALANE is purchased from Rongdo under the name NIKKOL SUGAR SQUALANE.
The octyl methicone content is 2-4%, and may be, for example, 2%, 2.1%, 2.3%, 3.1%, 3.4%, 3.7%, 4%, etc.; octyl methicone is available from Zhenbang under the name Silsoft 034.
The amount of DUB CIRE H1 is 0.5-2%, and may be, for example, 0.5%, 0.8%, 1.2%, 1.3%, 1.7%, 1.9%, 2%, etc.; DUB CIRE H1 mainly comprises C10-18 fatty acid triglycerides, which are available from petabyssal company under the name DUB CIRE H1.
The content of batyl alcohol is 0.1-0.5%, such as 0.1%, 0.2%, 0.3%, 0.4%, 0.5% etc.; it is selected from the product available from Rongdao under the name NIKKOL Batyl Alcohol 100.
The content of hydrogenated lecithin is 0.3-1%, and may be, for example, 0.3%, 0.5%, 0.6%, 0.8%, 0.9%, 1%, etc.; it is a product available from Rongdao under the name NIKKOLLecinolS-10.
Ubiquinone is present in an amount of 0.01 to 0.05%, and may be, for example, 0.01%, 0.02%, 0.03%, 0.04%, 0.05%, etc.; the product from nine peaks company under the name Coenzyme Q10 was selected.
The content of behenyl alcohol is 0.3-1%, and may be, for example, 0.3%, 0.5%, 0.6%, 0.7%, 0.8%, 0.9%, 1%, etc.; it is a product available from new ann under the name of Lanete 22.
The polydimethylsiloxane content is 0.5-1.5%, and may be, for example, 0.5%, 0.7%, 0.9%, 1.1%, 1.3%, 1.4%, 1.5%, or the like; it is a product available from san kesi under the name KF-96A-6T.
The content of tocopherol acetate is 0.1-0.5%, for example, may be 0.1%, 0.2%, 0.3%, 0.5%, etc.; it is a product available from Runfei corporation under the name Vitamin-E-Acetate.
The content of NATRULON H-6 is 2-5%, such as 2%, 2.3%, 2.8%, 3.4%, 4.6%, 5% etc.; it is a product available from the company Coxsalen under the name NATRULON H-6.
The content of glyceryl polyether-26 is 2-5%, and may be, for example, 2%, 2.7%, 3.2%, 3.8%, 4.1%, 4.6%, 5%, etc.; it is a product available from Baihabo company under the name LIPONIC EG-1.
TR-1 may be contained in an amount of 0.1 to 0.3%, for example, 0.1%, 0.15%, 0.18%, 0.23%, 0.25%, 0.29%, 0.3%, etc. It is selected from the product available from the megametric company under the name TR-1.
The content of sodium hyaluronate is 0.05-0.2%, and may be, for example, 0.05%, 0.08%, 0.1%, 0.13%, 0.18%, 0.19%, 0.2%, or the like. It was selected from a product available from Furuida under the name HA-TLM 20-40.
The content of dipotassium glycyrrhizinate is 0.01-0.2%, such as 0.01%, 0.05%, 0.04%, 0.1%, 0.16%, 0.19%, 0.2%, etc.; it is available from hong Jiu company.
Allantoin content is 0.1-0.5%, and may be, for example, 0.1%, 0.2%, 0.3%, 0.4%, 0.43%, 0.5%, etc.; it is a product available from Runfei under the name ALLANTOIN.
The content of EDTA-2 Na is 0.01-0.2%, and may be, for example, 0.01%, 0.05%, 0.04%, 0.1%, 0.16%, 0.19%, 0.2%, etc.; it is purchased from new ann company.
The content of SEPEPLUS S is 0.5-1%, for example, 0.5%, 0.6%, 0.7%, 0.8%, 0.85%, 1%, etc.; which was purchased from baihabo corporation.
The content of PC2000 is 0.06-0.18%, and may be, for example, 0.06%, 0.08%, 0.1%, 0.12%, 0.13%, 0.18%, etc.; it is purchased from Rongdao corporation.
SymDiol 68 is present in an amount of 0.3-0.5%, e.g., 0.3%, 0.31%, 0.34%, 0.37%, 0.4%, 0.41%, 0.5%, etc.; it is available from oxsnow.
The content of Hydrolite 5 is 2-5%, and may be, for example, 2%, 2.3%, 2.7%, 3%, 5%, etc.; it is available from oxsnow.
The content of the lees extract is 0.1-0.5%, and may be, for example, 0.1%, 0.2%, 0.3%, 0.4%, 0.5%, etc.
The content of DAWNERGY peptide solution C is 0.05-1%, and may be, for example, 0.05%, 0.09%, 0.2%, 0.5%, 0.7%, 1%, or the like. It is a product available from Rongdao under the product name DAWNERGY peptide solution C.
The content of the DECORINYL peptide solution C is 0.1-1%, and may be, for example, 0.1%, 0.5%, 0.7%, 0.9%, 0.75%, 0.55%, 1%, or the like. It is a product available from Rongdao under the product name DECORINYL peptide solution C.
The content of Argiline Amplified peptide solution is 1 to 4%, and may be, for example, 1%, 1.5%, 2.3%, 3.4%, 3.9%, 4%, or the like. It is a product available from Rongdao company under the product name Argiline Amplified peptide solution.
The content of ZPC-019S is 0.5 to 3%, and may be, for example, 0.5%, 0.7%, 0.9%, 1%, 1.2%, 1.6%, 2.5%, 3%, or the like. It is a product available under the product name ZPC-019S from surge peptide company.
SymRelief100 is contained in an amount of 0.01 to 0.5%, and may be, for example, 0.01%, 0.05%, 0.1%, 0.21%, 0.3%, 0.5%, or the like. SymRelief100 contains bisabolol and ginger (Zingiber OFFICINALE) root extract. It is purchased under the product name SymRelief100 from olympic.
Flos Matricariae Chamomillae (Chamomilla RECUTITA) flower oil content of 0.001-0.01%, such as 0.001%, 0.003%, 0.004%, 0.005%, 0.009%, 0.01%, etc.; it was purchased from the department of femtology.
The content of neroli oil is 0.001-0.01%, and may be, for example, 0.001%, 0.003%, 0.004%, 0.005%, 0.009%, 0.01%, etc.; it is purchased from wilfine corporation.
The content of the seed extract of Coffea ARABICA (Coffea ARABICA) is 0.01-1%, such as 0.001%, 0.003%, 0.004%, 0.005%, 0.009%, 0.01%, etc. It was purchased from Vietnam under the name BioGenic CellLite-220.
In this example, the remaining component of the feedstock was water; it is understood that in other embodiments of the present application, the starting material may also include other ingredients such as preservatives.
It should be noted that the above is only an illustration of the raw material source of the skin care product of the embodiments of the present application; and is not meant to be accessible only from the above sources.
It is further noted that the skin care products exemplified above are formed in the form of an emulsion; in other embodiments of the present application, the skin care product may be prepared as a lotion, cream, spray, or the like; specific ingredients can be set according to actual requirements, and the application does not limit the ingredients.
The skin care product provided by the embodiment of the application has the effect of effectively lightening wrinkles, can effectively lock the moisture of the skin, and has the effect of weakening fine wrinkles to different degrees on the grain of the skin, the raised line and the corner lines.
The present application also provides a method of making a skin care product, consisting essentially of:
mixing Montanov L, squalane, octyl polymethylsiloxane, DUB CIRE H1, batyl alcohol, hydrogenated lecithin, ubiquinone, behenyl alcohol, polydimethylsiloxane and tocopheryl acetate to obtain oil phase.
In some embodiments of the present application, the oil phase is obtained by continuously stirring and mixing, for example, the stirring speed is 2000 to 3000r/min, such as 2000r/min, 2100r/min, 2300r/min, 2500r/min, 2600r/min, 3000 r/min.
Mixing NATRULON H-6, glyceryl polyether-26, TR-1, sodium hyaluronate, dipotassium glycyrrhizinate, allantoin, disodium EDTA and water to obtain water phase.
Then mixing the oil phase and the water phase, adding the rest raw materials after mixing, and homogenizing, wherein in some embodiments, the stirring speed of homogenizing in the mixing process can be 2000-3000 r/min, for example, 2000r/min, 2200r/min, 2400r/min, 2500r/min, 2700r/min, 3000 r/min.
In some embodiments of the present application, after mixing the water phase and the oil phase, the temperature is first raised to 80-85 ℃ (for example, 80 ℃, 81 ℃, 83 ℃, 85 ℃), the sepplus S and the PC2000 are first added and mixed uniformly, then the temperature is reduced to 44-46 ℃ (for example, 44 ℃, 45 ℃, 46 ℃), and the rest raw materials are then added and mixed uniformly.
In some embodiments of the present application, the method of preparing a skin care product further comprises preparing a distiller's grains extract, comprising essentially the steps of:
mixing distiller's grains, butanediol, p-hydroxyacetophenone, and hexanediol at 80-90 deg.C (such as 80 deg.C, 81 deg.C, 83 deg.C, 85 deg.C, 87 deg.C, and 90 deg.C); then carrying out micro-jet extraction at room temperature and filtering to obtain filtrate.
In detail, the method comprises the steps of mixing a wine dreg raw material with a solid content of 20-29% with water, heating to 60-90 ℃, preserving heat for 20-30min, and then mixing with butanediol, p-hydroxyacetophenone and hexanediol, wherein the mass ratio of the wine dreg raw material to the butanediol, the p-hydroxyacetophenone to the hexanediol is 2: 1: 0.4: 0.4; after mixing, extraction was carried out using micro-jet extraction.
Then, carrying out centrifugal separation, removing filter residues, and removing the filter residues after filtering again by adopting a filter screen with the diameter of 2 mu m; sterilizing the filtrate by ultraviolet sterilization to obtain the distiller's grains extract.
It should be noted that in other embodiments of the present application, the distiller's grains extract can be prepared by other methods, or obtained by a commercially available method.
It should be noted that in the examples of the present application, there is no sequence between the preparation of the distiller's grains extract and the preparation of the aqueous phase and the oil phase.
The features and properties of the present application are described in further detail below with reference to examples.
Example 1
The embodiment provides a preparation method of a skin care product, which comprises the following steps:
1) preparing a wine dreg extract: heating the wine dreg water solution with the solid content of 25% to 84 ℃, wherein the mass ratio of the wine dreg water solution with the solid content of 20%, butanediol, p-hydroxyacetophenone and hexanedione is 2: 1: adding butanediol, p-hydroxyacetophenone and hexanedione in a ratio of 0.4: 0.4; after mixing, extraction was carried out using micro-jet extraction. Then, carrying out centrifugal separation, removing filter residues, and removing the filter residues after filtering again by adopting a filter screen with the diameter of 2 mu m; sterilizing the filtrate by ultraviolet sterilization to obtain the distiller's grains extract.
2) Taking the following raw materials in percentage by weight, wherein the total weight of all the raw materials is 2 kg:
3% Montanov L, available from Baihaobo;
3% SQUALANE, a product sold by Rongdao under the name NIKKOL SUGAR SQUALANE;
2% octyl methicone, available from Zhenbang under the name Silsoft 034;
2% DUB CIRE H1, available from pethida corporation;
0.5% Batyl Alcohol, a product available from Rongdao under the name NIKKOL Batyl Alcohol 100;
0.3% hydrogenated lecithin, a product available from Rongdao under the name NIKKOLLeci nolS-10;
0.05% ubiquinone, a product available from nine peaks under the name Coenzyme Q10;
0.7% behenyl alcohol, available from new ann under the name Lanete 22;
0.9% polydimethylsiloxane, a product available from san Kaes under the name KF-96A-6T;
0.3% tocopheryl Acetate, available from Runfei corporation under the name Vitamin-E-Acetate;
3% NATRULON H-6, a product available from the Corsala company under the name NATRULON H-6;
3% glyceryl polyether-26, available from Baihaobo company under the designation LIPONIC EG-1;
0.2% TR-1, a product available from Mega-scale under the name TR-1;
0.1% sodium hyaluronate, available from Florida under the name HA-TLM 20-40;
0.1% dipotassium glycyrrhizinate, available from sydow corporation;
0.4% ALLANTOIN, available from Ruiping under the name ALLANTOIN;
0.1% EDTA-2 Na, available from New Amphibian;
0.6% SEPELUS, available from Baihabo corporation;
0.1% PC2000, available from Rongdao corporation;
0.4% SymDiol 68 available from Orxue;
3% Hydrolite 5, available from Oryza sativa;
0.3% of a lees extract; step 1) preparing;
0.06% DAWNERGY peptide solution C, available from Rongdao corporation;
0.3% of DECORYL peptide solution C, available from Rongdao corporation;
1% Argiline Amplified peptide solution, available from Rongdao corporation;
0.5% ZPC-019S, a product of the product name ZPC-019S available from surge peptide corporation;
0.5% SymRelief100, a product sold by Orifice company under the product name SymRelief 100;
0.01% chamomile oil, purchased from phyloco;
0.01% neroli oil, purchased from wilfine;
1% extract of Coffea arabica seed, purchased from Viran under the name BioGenic CellLite-220; and the balance water.
3) Mixing Montanov L, squalane, octyl polymethylsiloxane, DUB CIRE H1, batyl alcohol, hydrogenated lecithin, ubiquinone, behenyl alcohol, polydimethylsiloxane and tocopheryl acetate to obtain oil phase.
4) Mixing NATRULON H-6, glyceryl polyether-26, TR-1, sodium hyaluronate, dipotassium glycyrrhizinate, allantoin, disodium EDTA and water to obtain water phase.
5) Mixing the water phase and the oil phase, heating to 84 deg.C, adding SEPEPLUS S and PC2000, mixing, cooling to 45 deg.C, adding the rest materials, and mixing; and cooling and packaging.
Test examples
The skin care product provided in example 1 (hereinafter referred to as a test product) was tested by selecting 30 healthy female subjects with dry and rough skin, loose skin and wrinkles in China, wherein the age range of the subjects is 35-60 years.
Respectively carrying out percutaneous water loss and skin elasticity measurement, analysis of statute lines, head raising lines and mouth corner lines before a test product is used by a subject, 7 days of a continuous product, 14 days of a continuous product and 28 days of a continuous product, carrying out visual evaluation on apple muscle and mandible lines of the subject by 3 visual sense evaluators, carrying out self evaluation by the subject according to a questionnaire, and comparing data results before and after the product is used with evaluation results through a statistical test method so as to judge whether a statistical difference exists.
The test environment is at 20.5-21.8 deg.c and 43.8-56.4% RH, and is in accordance with the requirement of scheme design.
And performing descriptive statistics on various measured values by using EXCEL software, wherein the statistics comprise quantity, mean value, standard deviation, minimum value, maximum value and the like.
And (3) comparing the measured values at different time points with the basic values by using SPSS analysis software, performing significance Test on data improvement value normal distribution by using Shapiro-Wilk Test, wherein if Sig (double sides) >0.01 shows normal distribution, performing pairing t Test, and taking the significance difference level alpha as 0.05. If Sig. (two-sided) <0.01, it is non-normally distributed and the Wilcoxon test is performed, and the level of significant difference α is taken to be 0.05.
After-use data-before-use data are obtained; boost/improvement after product use (percentage) versus (post-use data-pre-use data)/pre-use data.
The transdermal water loss before and after the use of the test product is compared and shown in table 1; the results of the statistical analysis of the amount of percutaneous water loss are shown in Table 2.
TABLE 1
Figure BDA0003049285880000121
TABLE 2
Figure BDA0003049285880000122
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
After 7 days of continuous use of the test product, the subjects had a significant improvement in cheek transdermal water loss of 8.34% (absolute) (p < 0.01); after 14 days of continuous use of the test product, the subjects had a significant improvement in cheek transdermal water loss of 12.02% (absolute) (p < 0.001); after 28 days of continuous use of the test product, the subjects had a significant improvement in cheek transdermal water loss of 22.05% (absolute) (p < 0.001);
the above shows that the test product can be used for 7 days, 14 days and 28 days continuously, the moisture loss of cheek skin can be obviously improved, and the skin barrier function is improved.
Table 3 shows the results of comparison of the R2 values of skin elasticity before and after use of the test product; table 4 shows the results of a statistical analysis of the R2 values for skin elasticity.
TABLE 3
Figure BDA0003049285880000131
TABLE 4
Figure BDA0003049285880000132
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
As can be seen from tables 3 and 4, the subject's cheek skin elasticity R2 value was significantly increased by 11.40% (p <0.001) after 7 days of continuous use of the test product; after 14 days of continuous use of the test product, the subject's cheek skin elasticity R2 value was significantly increased by 11.48% (p < 0.001); after 28 days of continuous use of the test product, the subject's cheek skin elasticity R2 value was significantly increased by 11.94% (p < 0.001); the results show that the test product can remarkably improve the R2 value of cheek skin elasticity after being continuously used for 7 days, 14 days and 28 days, and has the effects of improving the skin elasticity and tightening the skin.
Table 5 shows the comparison of the grain before and after use of the test product; table 6 shows the statistical analysis of the statutes before and after the use of the test products.
TABLE 5
Figure BDA0003049285880000141
TABLE 6
Figure BDA0003049285880000142
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
As can be seen from tables 5 and 6, after 7 days of continuous use of the test product, the subject's grain improved by 1.36% (absolute); after 14 days of continuous use of the test product, the subject's grain improved by 3.06% (absolute); after 28 days of continuous use of the test product, the subject's grain significantly improved by 12.53% (absolute) (p < 0.05); the result shows that the method can obviously improve the grain of the statute by continuously using the test product for 28 days and has the effect of fading the grain of the statute.
Table 7 shows the head-up line comparison before and after using the test product; table 8 shows the statistical analysis of the head-up line before and after the use of the test product.
TABLE 7
Figure BDA0003049285880000151
TABLE 8
Figure BDA0003049285880000152
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
As can be seen from tables 7 and 8: after 7 days of continuous use of the test product, the subject's raised head line improved by 2.31% (absolute); after 14 days of continuous use of the test product, the subjects showed a significant improvement in the raised head lines of 7.02% (absolute) (p < 0.01); after 28 days of continuous use of the test product, the subjects showed a significant improvement in the raised head line of 7.71% (absolute) (p < 0.001); the test product can be used for 14 days and 28 days continuously to remarkably improve the raised lines and has the effect of fading the raised lines.
Table 9 shows the mouth angularity comparison before and after use of the test product; table 10 shows the results of statistical analysis of the mouth angularity before and after use of the test products.
TABLE 9
Figure BDA0003049285880000153
Figure BDA0003049285880000161
Watch 10
Figure BDA0003049285880000162
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
As can be seen from tables 9 and 10: after 7 days of continuous use of the test product, the subjects had a 3.78% (absolute) improvement in the lip print; after 14 days of continuous use of the test product, subjects showed a significant improvement of 5.43% (absolute) in the lip line (p < 0.05); subjects showed a significant improvement in the lip print of 8.26% (absolute) (p <0.01) after 28 days of continuous use of the test product; the result shows that the mouth corner lines can be remarkably improved by continuously using the test product for 14 days and 28 days, and the mouth corner line fading effect is achieved.
Table 11 shows the mouth angularity comparison before and after use of the test product; table 12 shows the results of statistical analysis of the mouth angularity before and after the use of the test product.
TABLE 11
Figure BDA0003049285880000163
TABLE 12
Figure BDA0003049285880000164
Figure BDA0003049285880000171
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
As can be seen from tables 11 and 12: after 7 days of continuous use of the test product, apple muscle of the subject was significantly increased by 17.98% (p < 0.001); after 14 days of continuous use of the test product, subjects had a significant increase in apple muscle of 23.83% (p < 0.001); after 28 days of continuous use of the test product, apple muscle of the subject was significantly increased by 31.17% (p < 0.001); the results show that the apple muscle can be remarkably improved and the apple muscle can be plump by continuously using the test product for 7 days, 14 days and 28 days.
Table 13 shows the mouth angularity comparison before and after use of the test product; table 14 shows the results of statistical analysis of the mouth angularity before and after the use of the test product.
Watch 13
Figure BDA0003049285880000172
TABLE 14
Figure BDA0003049285880000173
Significance labeling method: "n.s." means no statistical difference, p > 0.05; "+" indicates significant difference, p is more than or equal to 0.01 and less than 0.05, "+" indicates significant difference, p is more than or equal to 0.001 and less than 0.01; "x" indicates significant difference, p < 0.001.
As can be seen from tables 13 and 14: after 7 days of continuous use of the test product, the mandible line of the subject was significantly increased by 16.32% (p < 0.001); after 14 days of continuous use of the test product, the mandible line of the subject was significantly increased by 16.86% (p < 0.001); after 28 days of continuous use of the test product, the mandible line of the subject was significantly increased by 17.04% (p < 0.001); it is shown that the mandible line can be significantly improved with mandible line lifting effect by continuously using the test product for 7 days, 14 days and 28 days.
In conclusion, the skin care product provided by the embodiment of the application has the effect of fading wrinkles.
The above description is only a preferred embodiment of the present application and is not intended to limit the present application, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present application shall be included in the protection scope of the present application.

Claims (10)

1. The skin care product is characterized by mainly comprising the following components in percentage by mass:
0.01-1% of bisabolol, 0.01-1% of ginger root extract, 0.001-0.05% of mother chrysanthemum oil, 0.001-0.05% of bitter orange flower oil and 0.01-2% of small fruit coffee seed extract.
2. The skin care product according to claim 1, characterized in that the skin care product mainly comprises the following components in percentage by mass:
0.01-0.5% of bisabolol, 0.01-0.5% of ginger root extract, 0.001-0.01% of chamomile oil, 0.001-0.01% of bitter orange flower oil and 0.01-1% of small-fruit coffee seed extract.
3. The skin care product according to claim 1 or 2, further comprising a lees extract obtained by extracting lees with an organic solvent, the organic solvent comprising butylene glycol, p-hydroxyacetophenone and hexanedione.
4. The skin care product according to claim 1, characterized in that the skin care product mainly comprises the following components in percentage by mass:
1-3% Montanov L, 1-3% squalane, 2-4% octyl methicone, 0.5-2% DUB CIRE H1, 0.1-0.5% batyl alcohol, 0.3-1% hydrogenated lecithin, 0.01-0.05% ubiquinone, 0.3-1% behenyl alcohol, 0.5-1.5% polydimethylsiloxane, 0.1-0.5% tocopheryl acetate, 2-5% NATRULON H-6, 2-5% glyceryl polyether-26, 0.1-0.3% TR-1, 0.05-0.2% sodium hyaluronate, 0.01-0.2% dipotassium glycyrrhizinate, 0.1-0.5% allantoin, 0.01-0.2% EDTA-2 Na, 0.5-1% SELUS, 0.06-0.18% PC, 0.3-0.5% Symphosol, 0.5-5% allantoin, 0.01-0.2% DAGY-2% alcohol extract, 0.5-5% alcohol extract, 0.05-5% alcohol extract, 0.1-1% of DECORYL peptide solution C, 1-4% of Argiline Amplified peptide solution, 0.5-3% of ZPC-019S, 0.01-0.5% of bisabolol, 0.01-0.5% of ginger root extract, 0.001-0.01% of chamomile oil, 0.001-0.01% of bitter orange flower oil, 0.01-1% of small fruit coffee seed extract and the balance of water.
5. Use of a skin care product according to any one of claims 1 to 4 for lightening skin lines.
6. A method for preparing a skin care product, comprising:
mixing Montanov L, squalane, octyl polymethylsiloxane, DUB CIRE H1, batyl alcohol, hydrogenated lecithin, ubiquinone, behenyl alcohol, polydimethylsiloxane and tocopheryl acetate to obtain oil phase;
mixing NATRULON H-6, glyceryl polyether-26, TR-1, sodium hyaluronate, dipotassium glycyrrhizinate, allantoin, EDTA disodium and water to obtain water phase;
mixing the water phase and the oil phase, adding the rest raw materials, and uniformly mixing.
7. The method for producing a skin care product according to claim 6,
and after the water phase and the oil phase are mixed, heating to 80-85 ℃, adding SEPEPLUS S and PC2000, uniformly mixing, then cooling to 44-46 ℃, and then adding the rest raw materials.
8. The method of claim 6, wherein the homogenizing speed is 2000-3000 r/min during the mixing process.
9. The method of claim 6, further comprising preparing a lees extract: mixing the aqueous solution containing distiller's grains, butanediol, p-hydroxyacetophenone and hexanedione at 80-90 deg.C; then carrying out micro-jet extraction at room temperature and filtering to obtain filtrate;
adding the distillers meal extract after the step of mixing the aqueous phase with the oil phase and mixing uniformly.
10. The method of claim 9, wherein in the step of preparing the distiller's grains extract, the centrifugal separation is performed after the micro-jet extraction, and then the filtrate obtained after the centrifugal separation is filtered through a filter screen of 2 μm to obtain the distiller's grains extract.
CN202110488774.3A 2021-04-30 2021-04-30 Skin care product, preparation method thereof and application thereof in skin line fading Pending CN113133963A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282078B (en) * 2022-08-29 2023-09-01 广东丸美生物技术股份有限公司 Full-effect eye cream and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104739723A (en) * 2015-03-19 2015-07-01 广东轻工职业技术学院 Tightening eye cream
CN106176521A (en) * 2016-07-29 2016-12-07 赵冰丽 A kind of facial mask essence increasing skin elasticity and preparation method
CN108670919A (en) * 2018-06-13 2018-10-19 北京日光旭升精细化工技术研究所 Natural crease-resistant smoothing wrinkle composition and its application and the eye cream comprising the composition
CN110269929A (en) * 2019-08-13 2019-09-24 滨海昌正企业管理有限公司 Have effects that the composition of skin repair and its application in cosmetics

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104739723A (en) * 2015-03-19 2015-07-01 广东轻工职业技术学院 Tightening eye cream
CN106176521A (en) * 2016-07-29 2016-12-07 赵冰丽 A kind of facial mask essence increasing skin elasticity and preparation method
CN108670919A (en) * 2018-06-13 2018-10-19 北京日光旭升精细化工技术研究所 Natural crease-resistant smoothing wrinkle composition and its application and the eye cream comprising the composition
CN110269929A (en) * 2019-08-13 2019-09-24 滨海昌正企业管理有限公司 Have effects that the composition of skin repair and its application in cosmetics

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
佚名: "丸美多重胜肽紧致淡纹精华乳", 《百度》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115282078B (en) * 2022-08-29 2023-09-01 广东丸美生物技术股份有限公司 Full-effect eye cream and preparation method thereof

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