CN113018222A - Multi-effect cream for barrier repair of sensitive skin - Google Patents

Multi-effect cream for barrier repair of sensitive skin Download PDF

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CN113018222A
CN113018222A CN202110387733.5A CN202110387733A CN113018222A CN 113018222 A CN113018222 A CN 113018222A CN 202110387733 A CN202110387733 A CN 202110387733A CN 113018222 A CN113018222 A CN 113018222A
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group
preparation
composition
extract
butanediol
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谢坤
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Dongshengyuan Research Institute Guangzhou Co Ltd
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Dongshengyuan Research Institute Guangzhou Co Ltd
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8129Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical; Compositions of hydrolysed polymers or esters of unsaturated alcohols with saturated carboxylic acids; Compositions of derivatives of such polymers, e.g. polyvinylmethylether
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    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
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    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
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    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
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Abstract

The invention belongs to the technical field of cosmetics, and discloses a multi-effect cream for repairing sensitive skin barriers, which comprises a cetearyl glucoside composition in a group A, jojoba seed oil, tocopherol, a preparation water in a group B, butanediol, a preparation water in a group C, carbomer, a polyacrylamide composition in a group D, a tetrahydroxypropyl ethylenediamine in a group E, a preparation water in a group F, sodium hyaluronate and a preparation butanediol composition in a group G, wherein the preparation components in the group H comprise caprylyl hydroxamic acid compositions PGE-2 prevents redness and erythema, and makes the skin softer after application without reducing the protective capacity of the skin's keratinous barrier.

Description

Multi-effect cream for barrier repair of sensitive skin
Technical Field
The invention belongs to the technical field of cosmetics, and particularly relates to a multi-effect cream for repairing a sensitive skin barrier.
Background
Sensitive muscles are individuals with symptoms of facial hyperreactivity to describe their skin, and it is considered that their skin is more vulnerable to the external environment or the invasion of facial products than normal people to cause hyperreactivity, which is problematic skin with symptoms of erythema and skin flushing, and is an excessive reaction of the skin, and an excessive sensory reaction of the skin caused by some external environmental factors including hard water and cosmetics.
Sensitive skin causes various skin problems such as dehydration, stinging heat, flushing, pustules, desquamation, etc., which are of great concern, and thus, a multi-effect cream for barrier repair of sensitive skin is provided.
Disclosure of Invention
In order to solve the above problems of the prior art, the present invention aims to provide a multi-effect cream for barrier repair against the problem of sensitive muscles.
The technical scheme adopted by the invention is as follows: a pleiotropic cream for barrier repair of sensitive muscle skin, which comprises A, B, C, D, E, F, G, H groups of preparations, wherein the ingredients of the A group of preparations comprise cetearyl glucoside composition, jojoba seed oil and tocopherol, the ingredients of the B group of preparations comprise water and butanediol, the ingredients of the C group of preparations comprise water and carbomer, the ingredients of the D group of preparations comprise polyacrylamide composition, the ingredients of the E group of preparations comprise tetrahydroxypropyl ethylenediamine, the ingredients of the F group of preparations comprise water and sodium hyaluronate, the ingredients of the G group of preparations comprise butanediol composition, the ingredients of the H group of preparations comprise caprylyl hydroximic acid composition, and the preparation method comprises the following steps:
s1, cleaning all tools and pot sets used in production, and sterilizing for later use; respectively dispersing and dissolving the preparation C and the preparation F for later use;
s2 adding the preparation of group B, the preparation of group C and the preparation of group F into an emulsifying pot, stirring, heating to 90 deg.C for dissolving completely, and sterilizing at constant temperature for 10 min; adding the group A preparation into an oil phase pot, stirring and heating to 80 ℃, and completely dissolving;
s3, starting homogenizing, pumping the oil phase pot raw materials, continuing homogenizing for 3min after adding, and stirring uniformly; cooling to 78 deg.C, adding the preparation D, homogenizing for 1min, and stirring; defoaming completely at constant temperature;
s4, adding the preparation E, and stirring uniformly;
s5, cooling to 45 ℃, adding the preparation in group G and the preparation in group H, and stirring uniformly;
s6, cooling to 38 ℃, filtering with 100-mesh filter cloth and discharging.
Further, the percentage ratio of the components of the preparation in the group A is cetearyl glucoside composition (2%), jojoba seed oil (6%), tocopherol (0.5%), the percentage ratio of the components of the B group preparation is water (54.23%) and butanediol (8%), the component of the C group preparation comprises water (20%) and carbomer (0.2%), the percentage ratio of the components of the D group preparation is polyacrylamide composition (1.5%), the percentage ratio of the components of the E group preparation is tetrahydroxypropylethylenediamine (0.24%), the component of the F group preparation comprises water (3%) and sodium hyaluronate (0.03%), the percentage ratio of the components of the G group preparation is butanediol composition (3.5%), and the percentage ratio of the components of the H group preparation is caprylhydroxamic acid composition (0.8%).
Still further, the cetearyl glucoside composition of group a formulation (2%) included cetearyl alcohol (5%), cetearyl glucoside (45%), sorbitan olivate (50%).
Furthermore, the polyacrylamide composition (1.5%) in the group D preparation comprises polyacrylamide (40%), C13-14 isoparaffin (15%), laureth-7 (5%), and water (40%).
Furthermore, the butylene glycol composition (3.5%) of the group G preparation comprises water (> 50%), butylene glycol (1-10%), 1, 2-hexanediol (1-5%), carboxymethyl chitosan (1-10%), a chamomile extract (3-12%), a mint leaf extract (2-10%), a pelargonium graveolens extract (2-10%), a purslane extract (2-8%), an aloe barbadensis extract (2-8%), a sophora flavescens root extract (2-8%), sodium benzoate (0.1-0.5%), potassium sorbate (0.1-0.5%) and glycerol (2-10%).
Further, the butylene glycol composition (3.5%) of the group G formulation included water (51%), butylene glycol (4%), 1, 2-hexanediol (2%), carboxymethyl chitosan (5%), a chamomile extract (9%), a mint leaf extract (3%), a geranium extract (7%), a purslane extract (5%), an aloe vera extract (3%), a ginseng root extract (8%), sodium benzoate (0.5%), potassium sorbate (0.5%), and glycerin (2%).
Further, the butylene glycol composition (3.5%) of the group G formulation included water (50.8%), butylene glycol (1%), 1, 2-hexanediol (5%), carboxymethyl chitosan (2%), a chamomile extract (12%), a mint leaf extract (10%), a geranium extract (2%), a purslane extract (2%), an aloe vera extract (8%), a sophora flavescens root extract (2%), sodium benzoate (0.1%), potassium sorbate (0.1%), and glycerin (5%).
Further, the formulation of group H, caprylhydroxamic acid composition (0.8%) included butylene glycol (60%), 1, 2-hexanediol (28%), caprylhydroxamic acid (11%).
The invention has the beneficial effects that:
the multi-effect cream for repairing the sensitive skin barrier provided by the invention has the multiple effects of immediate allergy relief, barrier repair, sedation, moisture retention and oxidation resistance, inhibits the primary reaction of inflammation by regulating cytokines to inhibit IL-1 alpha and TNF-alpha to prevent the reaction from inhibiting IL-6 and IL-8 from reducing redness from the source, and inhibits the secondary reaction of inflammation by regulating lipid mediators to inhibit COX-2 and PGE-2 to prevent redness and erythema.
The multi-effect cream has the effects of barrier repair and moisture preservation, can promote the moisture preservation capability of cells, and can repair the damage of a sebum membrane and a 'brick wall structure' for a long time; the traditional Chinese medicine composition has the effects of treating inflammation characterization, eliminating red swelling, inhibiting bacteria and resisting inflammation, increases the affinity and moisture retention of the formula by using a water molecule softening technology, enables the formula to bear more active ingredients without skin burden, and has higher synergistic effect with active substances. The skin is softer after use without reducing the protective capacity of the skin's keratinous barrier.
Detailed Description
The present invention is further illustrated below with reference to specific examples.
Example 1:
the embodiment provides a pleiotropic cream for barrier repair of sensitive muscle skin, which comprises A, B, C, D, E, F, G, H groups of preparations, wherein the ingredients of the A group of preparations comprise cetearyl glucoside composition, jojoba seed oil and tocopherol, the ingredients of the B group of preparations comprise water and butanediol, the ingredients of the C group of preparations comprise water and carbomer, the ingredients of the D group of preparations comprise polyacrylamide composition, the ingredients of the E group of preparations comprise tetrahydroxypropyl ethylenediamine, the ingredients of the F group of preparations comprise water and sodium hyaluronate, the ingredients of the G group of preparations comprise butanediol composition, the ingredients of the H group of preparations comprise caprylyl hydroximic acid composition, and the preparation method comprises the following steps:
s1, cleaning all tools and pot sets used in production, and sterilizing for later use; respectively dispersing and dissolving the preparation C and the preparation F for later use; s2 adding the preparation of group B, the preparation of group C and the preparation of group F into an emulsifying pot, stirring, heating to 90 deg.C for dissolving completely, and sterilizing at constant temperature for 10 min; adding the group A preparation into an oil phase pot, stirring and heating to 80 ℃, and completely dissolving; s3, starting homogenizing, pumping the oil phase pot raw materials, continuing homogenizing for 3min after adding, and stirring uniformly; cooling to 78 deg.C, adding the preparation D, homogenizing for 1min, and stirring; defoaming completely at constant temperature; s4, adding the preparation E, and stirring uniformly; s5, cooling to 45 ℃, adding the preparation in group G and the preparation in group H, and stirring uniformly; s6, cooling to 38 ℃, filtering with 100-mesh filter cloth and discharging.
Specifically, the percentage ratio of the components of the preparation in the group A is cetearyl glucoside composition (2%), jojoba seed oil (6%), tocopherol (0.5%), the percentage ratio of the components of the B group preparation is water (54.23%) and butanediol (8%), the component of the C group preparation comprises water (20%) and carbomer (0.2%), the percentage ratio of the components of the D group preparation is polyacrylamide composition (1.5%), the percentage ratio of the components of the E group preparation is tetrahydroxypropylethylenediamine (0.24%), the component of the F group preparation comprises water (3%) and sodium hyaluronate (0.03%), the percentage ratio of the components of the G group preparation is butanediol composition (3.5%), and the percentage ratio of the components of the H group preparation is caprylhydroxamic acid composition (0.8%).
Specifically, the proportion of the group A formulation cetearyl glucoside composition (2%) includes cetearyl alcohol (5%), cetearyl glucoside (45%), sorbitan olivate (50%), the proportion of the group D formulation polyacrylamide composition (1.5%) includes polyacrylamide (40%), C13-14 isoparaffin (15%), laureth-7 (5%), water (40%), the proportion of the group G formulation butylene glycol composition (3.5%) includes water (51%), butylene glycol (4%), 1, 2-hexanediol (2%), carboxymethyl chitosan (5%), chamomile extract (9%), peppermint leaf extract (3%), geranium extract (7%), purslane extract (5%), aloe vera extract (3%), and the like, The percentage of the extract of the root of the kuraria (8%), sodium benzoate (0.5%), potassium sorbate (0.5%), glycerin (2%), and the composition of the group H preparation caprylyl hydroximic acid (0.8%) comprises butanediol (60%), 1, 2-hexanediol (28%), and caprylyl hydroximic acid (11%).
Example 2:
the formula and the ratio of the multi-effect cream for sensitive skin barrier repair in the embodiment are basically the same as those in the embodiment 1, and the difference is that: a pleiotropic cream for barrier repair of sensitive muscle skin, which comprises A, B, C, D, E, F, G, H groups of preparations, wherein the ingredients of the A group of preparations comprise cetearyl glucoside composition, jojoba seed oil and tocopherol, the ingredients of the B group of preparations comprise water and butanediol, the ingredients of the C group of preparations comprise water and carbomer, the ingredients of the D group of preparations comprise polyacrylamide composition, the ingredients of the E group of preparations comprise tetrahydroxypropyl ethylenediamine, the ingredients of the F group of preparations comprise water and sodium hyaluronate, the ingredients of the G group of preparations comprise butanediol composition, the ingredients of the H group of preparations comprise caprylyl hydroximic acid composition, and the preparation method comprises the following steps: s1, cleaning all tools and pot sets used in production, and sterilizing for later use; respectively dispersing and dissolving the preparation C and the preparation F for later use; s2 adding the preparation of group B, the preparation of group C and the preparation of group F into an emulsifying pot, stirring, heating to 90 deg.C for dissolving completely, and sterilizing at constant temperature for 10 min; adding the group A preparation into an oil phase pot, stirring and heating to 80 ℃, and completely dissolving; s3, starting homogenizing, pumping the oil phase pot raw materials, continuing homogenizing for 3min after adding, and stirring uniformly; cooling to 78 deg.C, adding the preparation D, homogenizing for 1min, and stirring; defoaming completely at constant temperature; s4, adding the preparation E, and stirring uniformly; s5, cooling to 45 ℃, adding the preparation in group G and the preparation in group H, and stirring uniformly; s6, cooling to 38 ℃, filtering with 100-mesh filter cloth and discharging.
Specifically, the percentage ratio of the components of the preparation in the group A is cetearyl glucoside composition (2%), jojoba seed oil (6%), tocopherol (0.5%), the percentage ratio of the components of the B group preparation is water (54.23%) and butanediol (8%), the component of the C group preparation comprises water (20%) and carbomer (0.2%), the percentage ratio of the components of the D group preparation is polyacrylamide composition (1.5%), the percentage ratio of the components of the E group preparation is tetrahydroxypropylethylenediamine (0.24%), the component of the F group preparation comprises water (3%) and sodium hyaluronate (0.03%), the percentage ratio of the components of the G group preparation is butanediol composition (3.5%), and the percentage ratio of the components of the H group preparation is caprylhydroxamic acid composition (0.8%).
Specifically, the proportions of the group A formulation cetearyl glucoside composition (2%) include cetearyl alcohol (5%), cetearyl glucoside (45%), sorbitan olivate (50%), and the proportion of the group D formulation polyacrylamide composition (1.5%) includes polyacrylamide (40%), C13-14 isoparaffin (15%), laureth-7 (5%), water (40%), and the proportions of the group G formulation butylene glycol composition (3.5%), including water (50.8%), butylene glycol (1%), 1, 2-hexanediol (5%), carboxymethyl chitosan (2%), chamomile extract (12%), peppermint leaf extract (10%), geranium extract (2%), purslane extract (2%), aloe vera extract (8%), and mixtures thereof, The percentage of the extract of the root of the kuraria (2%), sodium benzoate (0.1%), potassium sorbate (0.1%), glycerin (5%), and the composition of the group H preparation caprylyl hydroximic acid (0.8%) comprises butanediol (60%), 1, 2-hexanediol (28%), and caprylyl hydroximic acid (11%).
The present invention is not limited to the above-described alternative embodiments, and various other forms of products can be obtained by anyone in light of the present invention. The above detailed description should not be taken as limiting the scope of the invention, which is defined in the claims, and which the description is intended to be interpreted accordingly.

Claims (8)

1. The multi-effect cream for sensitive skin barrier repair is characterized in that: the preparation comprises A, B, C, D, E, F, G, H groups of preparations, wherein the ingredients of the A group of preparations comprise cetearyl glucoside composition, jojoba seed oil and tocopherol, the ingredients of the B group of preparations comprise water and butanediol, the ingredients of the C group of preparations comprise water and carbomer, the ingredients of the D group of preparations comprise polyacrylamide composition, the ingredients of the E group of preparations comprise tetrahydroxypropyl ethylenediamine, the ingredients of the F group of preparations comprise water and sodium hyaluronate, the ingredients of the G group of preparations comprise butanediol composition, the ingredients of the H group of preparations comprise caprylyl hydroximic acid composition, and the preparation method comprises the following steps:
s1, cleaning all tools and pot sets used in production, and sterilizing for later use; respectively dispersing and dissolving the preparation C and the preparation F for later use;
s2 adding the preparation of group B, the preparation of group C and the preparation of group F into an emulsifying pot, stirring, heating to 90 deg.C for dissolving completely, and sterilizing at constant temperature for 10 min; adding the group A preparation into an oil phase pot, stirring and heating to 80 ℃, and completely dissolving;
s3, starting homogenizing, pumping the oil phase pot raw materials, continuing homogenizing for 3min after adding, and stirring uniformly; cooling to 78 deg.C, adding the preparation D, homogenizing for 1min, and stirring; defoaming completely at constant temperature;
s4, adding the preparation E, and stirring uniformly;
s5, cooling to 45 ℃, adding the preparation in group G and the preparation in group H, and stirring uniformly;
s6, cooling to 38 ℃, filtering with 100-mesh filter cloth and discharging.
2. The multi-effect cream for sensitive muscle skin barrier repair of claim 1, wherein: the composition of the preparation group A comprises, by percentage, a cetearyl glucoside composition (2%), jojoba seed oil (6%) and tocopherol (0.5%), the composition of the preparation group B comprises, by percentage, water (54.23%) and butanediol (8%), the composition of the preparation group C comprises, by percentage, water (20%) and carbomer (0.2%), the composition of the preparation group D comprises, by percentage, a polyacrylamide composition (1.5%), the composition of the preparation group E comprises, by percentage, tetrahydroxypropylethylenediamine (0.24%), the composition of the preparation group F comprises, by percentage, water (3%), sodium hyaluronate (0.03%), the composition of the preparation group G comprises, by percentage, a butanediol composition (3.5%), and the composition of the preparation group H comprises, by percentage, a caprylhydroxamic acid composition (0.8%).
3. The multi-effect cream for sensitive muscle skin barrier repair of claim 2, wherein: the group a formulation cetearyl glucoside composition (2%) included cetearyl alcohol (5%), cetearyl glucoside (45%), sorbitan olivate (50%).
4. The multi-effect cream for sensitive muscle skin barrier repair of claim 2, wherein: the polyacrylamide composition (1.5%) of the D group preparation comprises polyacrylamide (40%), C13-14 isoparaffin (15%), laureth-7 (5%) and water (40%).
5. The multi-effect cream for sensitive muscle skin barrier repair of claim 2, wherein: the composition of the G group preparation butanediol (3.5%) comprises water (> 50%), butanediol (1-10%), 1, 2-hexanediol (1-5%), carboxymethyl chitosan (1-10%), a chamomile extract (3-12%), a mint leaf extract (2-10%), a pelargonium graveolens extract (2-10%), a purslane extract (2-8%), an aloe vera extract (2-8%), a picrasma root extract (2-8%), sodium benzoate (0.1-0.5%), potassium sorbate (0.1-0.5%) and glycerol (2-10%).
6. The multi-effect cream for sensitive muscle skin barrier repair of claim 2, wherein: the composition of the butanediol (3.5%) in the group G preparation comprises water (51%), butanediol (4%), 1, 2-hexanediol (2%), carboxymethyl chitosan (5%), a chamomile extract (9%), a mint leaf extract (3%), a geranium extract (7%), a purslane extract (5%), an aloe barbadensis extract (3%), a picrasma root extract (8%), sodium benzoate (0.5%), potassium sorbate (0.5%) and glycerol (2%).
7. The multi-effect cream for sensitive muscle skin barrier repair of claim 2, wherein: the composition of the butanediol (3.5%) in the group G preparation comprises water (50.8%), butanediol (1%), 1, 2-hexanediol (5%), carboxymethyl chitosan (2%), a chamomile extract (12%), a mint leaf extract (10%), a pelargonium graveolens extract (2%), a purslane extract (2%), an aloe barbadensis extract (8%), a picrasma root extract (2%), sodium benzoate (0.1%), potassium sorbate (0.1%) and glycerol (5%).
8. The multi-effect cream for sensitive muscle skin barrier repair of claim 2, wherein: the H group preparation of caprylyl hydroximic acid composition (0.8%) comprises butanediol (60%), 1, 2-hexanediol (28%), and caprylyl hydroximic acid (11%).
CN202110387733.5A 2021-04-12 2021-04-12 Multi-effect cream for barrier repair of sensitive skin Pending CN113018222A (en)

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