KR100865562B1 - Cmposition make use of beauty - Google Patents

Cmposition make use of beauty Download PDF

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KR100865562B1
KR100865562B1 KR1020080028378A KR20080028378A KR100865562B1 KR 100865562 B1 KR100865562 B1 KR 100865562B1 KR 1020080028378 A KR1020080028378 A KR 1020080028378A KR 20080028378 A KR20080028378 A KR 20080028378A KR 100865562 B1 KR100865562 B1 KR 100865562B1
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South Korea
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extract
skin
weight
grapefruit
chamomile
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KR1020080028378A
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Korean (ko)
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백호균
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(주)비에스인터내셔날
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin

Abstract

A cosmetic composition comprising plant extracts is provided to improve or treat atopic dermatitis and noninfectious skin diseases without reverse reactions including drug dependency, side effects and complication. A cosmetic composition for improving atopic dermatitis and noninfectious skin diseases comprises 0.0001-10 wt.% of crystalsome which is prepared by encapsulating vitamin A, vitamin C and SOD(superoxide dismutase) in spherical particles, 0.0001-10 wt.% of aloe vera gel, 0.0001-10 wt.% of fucogel1000PP(NICI Name: biosaccharide gum-1), and 0.0001-10 wt.% of carrot extract, 0.0001-10 wt.% of cucumber extract, 0.0001-10 wt.% of chamomile extract and 0.0001-10 wt.% of grapefruit extract which are prepared by extracting carrot, cucumber, chamomile or grapefruit with C1-C3 anhydrous or hydrous alcohol or ethyl acetate at 4-30 deg. C for 3-20 days, and is used as soft skin lotion, soft milk lotion, nutrition cream, massage cream, essence or pack.

Description

화장료용 조성물{Cmposition make use of Beauty} Cosmetic composition {Cmposition make use of Beauty}

본 발명은 피부의 개선을 위해서 사용하는 화장료 조성물에 관한 것으로, 특히 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물을 유효성분으로 함유하여 아토피와 비감염성 피부 개선에 특효가 있는 화장료 조성물에 관한 것이다.The present invention relates to a cosmetic composition used to improve the skin, in particular, crystal aloe, aloe vera gel, fucogel 1000PP, carrot extract, cucumber extract, chamomile extract, grapefruit extract as an active ingredient to improve atopy and non-infectious skin It relates to the cosmetic composition which is effective in.

일반적으로 아토피(atopy)라 함은 "잘 모른다"라는 뜻으로 그 원인을 알 수 없기 때문에 붙여진 이름이다. 이 피부 질환의 대표적인 특징은 살이 접히는 무릎, 팔목, 목 등에 건조증이 일어나며 가려움증 증상이 생긴다. 그리고 접히지 않는 부분에도 일종의 건조증 증상인 마른 버짐이 생길 수 있으며 붉은 모양이 얼굴과 눈 등에 생길 수 있다. 가려움증으로 인하여 이 질환을 오래 겪은 사람들은 2차적인 감염증과 불안, 불면증을 일으키기도 한다.In general, atopy means "I don't know" and is given because the cause is unknown. A typical feature of this skin disease is dryness in the knees, wrists, necks and the folds of the flesh, and itching symptoms. In addition, unfolded areas may cause dry ringworm, a symptom of dryness, and redness on the face and eyes. People who have had this disease for a long time due to itching may develop secondary infections, anxiety and insomnia.

현대 의학에서 이와 같은 질병에 사용되고 있는 약물들은 대부분 "스테로이드 호로몬제/항생제/항히스타민제"로서 이들을 내복약/주사제/외용약 등으로 장기간 사용하면 "약물 의존성(중독성)/부작용/합병증"등 3가지 역반응이 발생하게 되는 문제가 있다.Most of the drugs used in these diseases in modern medicine are "steroid hormones / antibiotics / antihistamines", and when they are used for long-term use as internal medicines, injections, or external medicines, three adverse reactions such as "drug dependence" (adverse toxicity) / side effects / complications " There is a problem that occurs.

따라서 본 발명의 목적은 이와 같은 문제점을 해결하기 위한 것으로, 3가지 역반응이 전혀 나타나지 않으면서 아토피와 비감염성 피부 질환을 완화하여 깨끗한 피부로 유지할 수 있게 한 화장료 조성물을 제공하는 데 있다.Accordingly, an object of the present invention is to solve the above problems, and to provide a cosmetic composition that can maintain a clean skin by relieving atopic and non-infectious skin diseases without any three adverse reactions.

상기와 같은 목적을 달성하기 위한 본 발명은 청구항1 기재의 화장료 조성물에는 크리스탈좀, 알로에 베라겔, 푸코겔1000PP(NICI Name:Biosaccharide Gum-1), 당근 추출물, 오이 추출물, 캐모마일 추출물 및 자몽 추출물을 혼합 조성한 혼합추출물을 유효성분으로 하여 함유하는 것을 특징으로 한다.The present invention for achieving the above object is a crystal composition, aloe vera gel, Foucault gel 1000PP (NICI Name: Biosaccharide Gum-1), carrot extract, cucumber extract, chamomile extract and grapefruit extract in the cosmetic composition of claim 1 Characterized in that the mixed extract as an active ingredient.

상기 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물은 화장료 조성물의 총 중량에 각각 0.0001~10중량%를 함유시킨 것을 특징으로 한다.The crystals, aloe vera gel, Foucault gel 1000PP, carrot extract, cucumber extract, chamomile extract, grapefruit extract is characterized in that the total weight of the cosmetic composition contained 0.0001 to 10% by weight.

상기 목적 및 장점 그리고 다른 특징은 아래의 설명으로부터 명백할 것이다.The above objects, advantages and other features will be apparent from the description below.

이하, 본 발명의 바람직한 실시예를 설명하면 다음과 같다.Hereinafter, preferred embodiments of the present invention will be described.

본 발명에 따른 화장료 조성물은 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물에서 선택된 2가지 이상의 혼합추출물을 유효성분으로 함유한 것이다.The cosmetic composition according to the present invention contains two or more mixed extracts selected from crystals, aloe vera gel, fucogel 1000PP, carrot extract, cucumber extract, chamomile extract, and grapefruit extract as an active ingredient.

상기에서 크리스탈좀(Crystalsome)은 비타민 A(레티놀), 비타민 C, SOD 등의 활성 성분을 좀(some), 즉 "구"에 포접시켜 안정화시킨 것이다. 활성 성분을 안정 화시키기 위해서 유도체를 사용했던 기존과는 달리 좀에 쌓여 있으므로 효과가 뛰어날 뿐만 아니라 안정하다. 이러한 크리스탈 좀은 피부 친화성이 탁월하고, 피부 침투력이 뛰어나 흡수가 잘 된다. 또 산화환원 반응으로부터의 보호 효과가 탁월하며, 크기 또한 나노 사이즈로 아주 미세하기 때문에 흡수나 사용 감이 탁월하다. Crystalsome is a crystalsome (Crystalsome) is the active ingredient, such as vitamin A (retinol), vitamin C, SOD is stabilized by inclusion (some), that is, "spheres". Unlike the existing ones, which used derivatives to stabilize the active ingredient, it is not only excellent in effect but also stable. These crystal moths have excellent skin affinity and excellent skin penetration, so they are easily absorbed. In addition, it is excellent in the protection effect from redox reaction, and its size is also very fine in nano size, so it is excellent in absorption and usability.

상기 알로에 베라겔(Aloe Vera Gel)은 보습효과가 탁월하고, 멜라닌 색소형성 억제효과(알로에 내의 화이트 성분)는 피부를 보호한다. 또한 다당류 성분이 저하된 면역능력을 신속하게 거의 정상치 수준으로 회복시켜 준다. 보통 아토피는 피부의 면역력 저하로 보고 있기 때문에, 다당류 성분은 아토피 피부의 개선에 탁월한 효과를 갖는다. 또한 알프로젠 성분이 알러지 반응을 억제한다. 또한 바르바로인, 알로에모징, 알로에닌 등이 함유되어 있어 살균, 소염작용이 있으며, 특히 피부염에 뛰어난 효과를 갖는다.The aloe vera gel (Aloe Vera Gel) has an excellent moisturizing effect, melanin pigmentation inhibitory effect (white component in aloe) protects the skin. In addition, the polysaccharide component quickly restores the reduced immune capacity to almost normal levels. Since atopic dermatitis is generally regarded as a decrease in the immunity of the skin, the polysaccharide component has an excellent effect on improving atopic skin. In addition, the alprogen component inhibits allergic reactions. In addition, it contains barbaroin, aloe mossing, aloenin, etc., which has bactericidal and anti-inflammatory effects, and in particular, has an excellent effect on dermatitis.

푸코겔1000PP(국제전문용어(INCI Name):Biosaccharide Gum-1)는 피부자극을 완화하는데 탁월하다. Fucose, Galactose, Galacturonigne acid의 세가지 당이 연속적으로 연결된 구조로, 특히 Fucose는 Anti-Allergy 물질로 초민감성 제품에 응용된다.Fucogel 1000PP (INCI Name: Biosaccharide Gum-1) is excellent for alleviating skin irritation. Fucose, Galactose, and Galacturonigne acid have three sugars in a row. In particular, Fucose is an anti-allergy substance and is applied to ultra-sensitive products.

당근 추출물(Carrot Ext)은 피부를 매끄럽게 하는 기능을 발휘한다. 주요 성분인 베타카로틴은 몸 안에 들어가 프로비타민 A로 바뀌는데, 그 비타민 A가 피부를 매끄럽게 한다. 그 비타민 A는 살결이 거칠어짐을 방지하고, 피부의 저항력이 떨어지는 것을 방지한다.Carrot Extract (Carrot Ext) works to smooth the skin. Beta-carotene, the main ingredient, enters the body and turns into provitamin A, which is vitamin A that smoothes the skin. The vitamin A prevents roughening of the skin and prevents the skin from falling off.

또한, 오이 추출물(Cucumber Ext)은 그 주성분이 엽록소와 비타민 C다. 미백 과 보습의 효과가 있고, 피부를 항상 촉촉하게 유지해 준다. 인체에 열독이 올라오는 것을 막아주는 기능이 있어 특히, 아토피 피부 질환 개선에 탁월하다. 또한 콜라겐을 다량 함유하고 있어 피부 노화를 억제한다.Cucumber extract (Cucumber Ext) is the main component of chlorophyll and vitamin C. It has the effect of whitening and moisturizing, and keeps skin moist. It has a function to prevent heat poisoning from coming up in the human body, and it is especially excellent for improving atopic skin disease. It also contains large amounts of collagen, which helps to prevent skin aging.

또 캐모마일 추출물(Chamomile Ext)은 카마줄렌(chamazulene)이라는 강한 항염제를 함유하고 있어 피부 건조를 방지하고, 과민성 피부를 진정시킨다. 또한 피부연화제(skin softner)작용을 한다.Chamomile Ext also contains a strong anti-inflammatory agent called chamazulene, which prevents skin from drying out and soothes sensitive skin. It also acts as a skin softner.

자몽 추출물(Grapefruit Ext)은 피지 조절과 세균 감염을 예방하면서 여드름에 의한 모공 확대 및 염증악화를 억제하는 등 피부 개선에 탁월한 효과가 있으며, 또한 비타민 C를 다량 함유하고 있어 피부 미용에 효과가 있다.Grapefruit extract (Grapefruit Ext) has excellent effects on skin improvement, including sebum control and prevention of bacterial infections, enlargement of pores caused by acne, and inflammation exacerbation.

이처럼 아토피와 비감염성 피부 개선에 특효가 있는 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물은 조성물의 총 중량에 각 0.0001~10중량%가 함유됨이 바람직하다. 0.0001중량% 미만이면 그 효과를 기대하기 어렵고, 10중량%를 초과하게 되면 효능은 좋아지나 기본 화장료 조성물의 성능을 약화시킬 우려가 있기 때문에 10중량%가 바람직하다.As described above, the crystals, aloe vera gel, fucogel 1000PP, carrot extracts, cucumber extracts, chamomile extracts and grapefruit extracts, which are effective in improving atopy and non-infectious skin, preferably contain 0.0001 to 10% by weight of the total weight of the composition. . If it is less than 0.0001 weight%, the effect is hard to expect, and if it exceeds 10 weight%, an efficiency will improve but 10 weight% is preferable because it may weaken the performance of a basic cosmetic composition.

크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물을 유효성분으로 함유하는 본 발명은 로션 성상으로, 피부에 발라 기존의 3가지 역반응 없이 아토피와 비감염성 피부 질환을 크게 개선하는 작용을 한다. .The present invention, which contains crystals, aloe vera gel, fucogel 1000PP, carrot extract, cucumber extract, chamomile extract, and grapefruit extract as an active ingredient, has a lotion property, which is applied to the skin to prevent atopic and non-infectious skin diseases without the conventional three adverse reactions. It greatly improves the work. .

본 발명의 당근, 오이, 캐모마일, 자몽 추출물을 얻기 위한 추출방법은 다음과 같다.Carrot, cucumber, chamomile, grapefruit extract of the present invention extraction method is as follows.

본 발명의 당근, 오이, 캐모마일, 자몽 추출물은 건조하지 않은 상태로 탄소수 1∼3의 무수 또는 함수 알코올, 또는 에틸 아세테이트로 4∼30℃에서 3∼20일간 추출한 다음, 농축하여 제조할 수 있다.The carrot, cucumber, chamomile and grapefruit extracts of the present invention may be prepared by extracting anhydrous or hydrous alcohols having 1 to 3 carbon atoms or ethyl acetate at 4 to 30 ° C. for 3 to 20 days without drying, and then concentrating.

또한, 상기 추출물은 건조되기 전의 당근, 오이, 캐모마일, 자몽을 물,탄소수 1∼3의 무수 또는 함수 알코올, 또는 에틸 아세테이트로 50∼100℃에서 3∼24시간 동안 추출한 다음, 농축하여 제조할 수 있다.In addition, the extract can be prepared by extracting carrot, cucumber, chamomile, grapefruit before drying with water, anhydrous or hydrous alcohol of 1 to 3 carbon atoms, or ethyl acetate for 3 to 24 hours at 50 to 100 ℃, and then concentrated. have.

또한, 상기 추출물은 추출공정의 수행 전 또는 후에 디에틸에테르 가용성분을 제거한 다음, 농축함으로써 더욱 정제된 상기의 추출물로 제조할 수 있다.In addition, the extract may be prepared as the extract further purified by removing the diethyl ether soluble component before or after performing the extraction process, and then concentrated.

상기 추출공정에 있어서, 당근, 오이, 캐모마일, 자몽을 잘게 세절하여 사용하는 것이 바람직하고, 추출용매는 시료 중량에 대하여 1∼15배로 가하는 것이 바람직하며, 유효 성분의 증발을 방지하기 위하여 냉각 콘덴서를 장착하여 추출하는 것이 바람직하다.In the above extraction step, it is preferable to use finely cut carrots, cucumbers, chamomile, grapefruit, extraction solvent is added 1 to 15 times the weight of the sample, and to prevent the evaporation of the active ingredient It is preferable to mount and extract.

상기와 같이 제조된 추출물은 통상의 화장료 첨가제를 혼합하여 통상의 방법으로 미백 화장료로 제조될 수 있으며, 통상적인 기초화장료, 예를 들어 유연화장수(스킨), 영양화장수(밀크로션), 영양크림, 맛사지크림, 엣센스, 팩 등에 첨가되어 제조될 수 있다. The extract prepared as described above may be prepared as a whitening cosmetic by a conventional method by mixing a common cosmetic additive, a conventional basic cosmetics, for example, soft cosmetics (skin), nutrient cosmetics (milk lotion), nutrition cream, It may be added to massage creams, essences, packs and the like.

상기 화장료에 사용되는 추출물 량은 통상의 화장료에 대하여 0.0001∼10중량%가 바람직하다.As for the extract amount used for the said cosmetics, 0.0001-10 weight% is preferable with respect to normal cosmetics.

본 발명에 의하면, 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물로 인하여 3가지 역반응이 전혀 나타나지 않으면서 아토피와 비감염성 피부 질환을 완화하는 기능을 발휘하여 피부를 탄력있고 깨끗하게 유지할 수 있는 기능을 발휘하는 효과가 있다.According to the present invention, the crystals, aloe vera gel, fucogel 1000PP, carrot extract, cucumber extract, chamomile extract, grapefruit extract due to the three adverse reactions do not appear at all the function to alleviate atopic and non-infectious skin diseases It has the effect of exerting the ability to keep elastic and clean.

이하, 본 발명을 하기 참고예들과 아울러 실시예 및 실험 예를 통하여 더욱 상세히 설명한다. 그러나 본 발명이 이에 한정되는 것은 아니다.Hereinafter, the present invention will be described in more detail with reference to the following Examples and Examples and Experimental Examples. However, the present invention is not limited thereto.

<참고예1>Reference Example 1

건조하지 않은 당근 100g을 잘게 세절하여 70% 에틸알코올 1L에 넣고 상온에서 1주일간 침적시켜 추출한 후 300 메쉬의 입도를 갖는 여과지로 여과하고 1주일간 방치하여 침전물을 에드벤텍 사의 7번 여과지로 2번 여과하였다. 그리고 감압 농축기를 이용하여 50℃에서 완전히 농축하여 건조 중량 17.6g 얻었다.Finely chopped 100 g of undried carrots, put it in 1L of 70% ethyl alcohol, extract it for 1 week at room temperature, extract it, filter it with a filter paper having a particle size of 300 mesh, and leave it for 1 week. The precipitate is filtered twice with filter No. 7 of Edbentech. It was. Then, the resultant was concentrated completely at 50 ° C. using a vacuum concentrator to obtain a dry weight of 17.6 g.

<참고예 2>Reference Example 2

건조하지 않은 오이 100g를 잘게 세절하여 30% 에틸알코올 1L에 넣고 실온에서 1주일간 침적시켜 추출한 후 300 메쉬의 입도를 갖는 여과지로 여과하고 1주일간 방치하여 얻은 침전물을 상기 참고예1과 동일하게 여과하였다. 그리고 감압 농축기를 이용하여 50℃로 완전히 농축하여 건조 중량 15.8g를 얻었다.100 g of undried cucumber was finely chopped, placed in 1 L of 30% ethyl alcohol, and extracted by immersion at room temperature for 1 week, filtered through a filter paper having a particle size of 300 mesh, and the precipitate obtained by standing for 1 week was filtered in the same manner as in Reference Example 1. . Then, the resultant was concentrated completely at 50 ° C. using a reduced pressure concentrator to obtain a dry weight of 15.8 g.

<참고예3>Reference Example 3

건조하지 않은 캐모마일 100g를 잘게 세절하여 70% 에틸알코올 1L에 넣고 냉각 콘데서가 달린 추출기에서 80℃로 8시간 끓여서 추출한 후 300메쉬의 입도를 갖는 여과지로 여과하고 1주일간 방치하여 얻은 침전물을 상기 참고예1과 동일하게 여과하였다.그리고 감압 농축기를 이용하여 50℃에서 완전히 농축하여 건조 중량 9.7g를 얻었다.Finely chopped 100 g of undried chamomile in 1 L of 70% ethyl alcohol, boiled at 80 ° C. for 8 hours in an extractor equipped with a cooling condenser, filtered with a filter paper having a particle size of 300 mesh, and left for 1 week to obtain a precipitate obtained by the reference example. Filtration was carried out in the same manner as in 1. Then, the mixture was concentrated completely at 50 ° C. using a vacuum concentrator to obtain a dry weight of 9.7 g.

<참고예4>Reference Example 4

건조하지 않은 자몽 100g를 잘게 세절하여 30% 에틸알코올 1L에 넣고 냉각 콘데서가 달린 추출기에서 80℃로 8시간 끓여서 추출한 후 300메쉬의 입도를 갖는 여과지로 여과하고 1주일간 방치하여 얻은 침전물을, 상기 참고예1과 동일하게 여과하였다. 그리고 감압 농축기를 이용하여 50℃로 완전히 농축하여 건조 중량 16.23g를 얻었다.Finely squeezed 100 g of undried grapefruit into 1 L of 30% ethyl alcohol, extracted by boiling at 80 ° C. for 8 hours in an extractor equipped with a cooling condenser, filtered through a filter paper having a particle size of 300 mesh, and left for 1 week. Filtration was carried out as in Example 1. Then, the resultant was concentrated completely at 50 ° C. using a vacuum concentrator to obtain a dry weight of 16.23 g.

<참고예5>Reference Example 5

건조하지 않은 당근, 오이, 캐모마일, 자몽 100g를 잘게 세절하여 물 1L에 넣고 냉각 콘데서가 달린 추출기에서 80℃로 8시간 끓여서 추출한 후 300메쉬의 입도를 갖는 여과지로 여과하고 1주일간 방치하여 얻은 침전물을, 상기 참고예1과 동일하게 여과하였다. 그리고 감압 농축기를 이용하여 50℃로 완전히 농축하여 건조 중량15.3g를 얻었다. Finely chop 100 g of undried carrots, cucumbers, chamomile, and grapefruit into 1 liter of water, boil it at 80 ° C for 8 hours in an extractor equipped with a cooling condenser, filter it with a filter paper with a particle size of 300 mesh, and leave for 1 week. Filtration was performed in the same manner as in Reference Example 1. Then, the resultant was concentrated completely at 50 ° C. using a vacuum concentrator to obtain a dry weight of 15.3 g.

<참고예 6>Reference Example 6

건조하지 않은 캐모마일, 자몽 100g를 잘게 세절하여 70% 에틸알코올 1L에 넣고 냉각 콘데서가 달린 추출기에서 80℃로 8시간 끓여서 추출한 후 300메쉬의 입도를 갖는 여과지로 여과하고 1주일간 방치하여 얻은 침전물을, 상기 참고예1과 동일하게 여과하였다. 이 추출물을 디에틸에테르 1L를 가하여 잘 섞어준 후 두 층으로 완전히 분리시켜 하층인 수층에 다시 1L의 에틸아세테이트를 가하여 잘 섞어준 후 두 층으로 완전히 분리시켜 에틸아세테이트 층을 감압 농축기를 이용하여 55℃로 완전히 농축하여 건조 중량 6.9g를 얻었다.Finely dried 100 g of undried chamomile and grapefruit, 1L of 70% ethyl alcohol, boiled at 80 ° C in an extractor equipped with a cooling condenser for 8 hours, extracted with filtered paper having a particle size of 300 mesh, and left for 1 week. Filtration was performed in the same manner as in Reference Example 1. 1L of diethyl ether was added to the mixture, and the mixture was thoroughly separated. The mixture was completely separated into two layers. Then, 1L of ethyl acetate was added to the lower aqueous layer, mixed well. The mixture was separated into two layers and the ethyl acetate layer was separated using a reduced pressure concentrator. It was concentrated completely at 占 폚 to obtain a dry weight of 6.9 g.

<실시예1><Example 1>

먼저, 1,3-BG(1,3-buthylene glycol), 글리세린(glycerine), 페녹시에탄올(phenoxyethanol), 방부제(danisol-M)를 80~82℃에서 혼합하여 완전 용해하여 1차 혼합물을 조성하고, 그 1차 혼합물에 정제수(DI-Water), EDTA-2Na(ethylene diamine tera acetic acid disodium salt diharate), 디포타슘 글리시르히지네이트(dipotassium glycyrrhizinate:DPG), 폴리에틸렌글리콜-4000S(PEG-4000S;ployetylene grycogen-4000s), 아미노코트(Aminocoat;Betain), 루브라젤(Lubrajel DV), 카보폴940(Carbopol 940;Carboxy Vinyl Polymer), 카보폴 941(Carbopol 941;Carboxy Vinyl Polymer), 나트라졸(Natrasol 250HR;Hydroxy Ethyl Cellulose), 하이드록시산(HA1%)을 차례로 투입후 50~52℃에서 10분 동안 완전 분산하여 2차 혼합물을 조성하였다. 이때, 페녹시에탄올은 조성물의 총 중량에 0.3중량%를, 방부제는 0.15중량%를, EDTA-2Na는 0.03중량%를 각각 투입하였다.First, 1,3-BG (1,3-buthylene glycol), glycerin (glycerine), phenoxyethanol (phenoxyethanol), preservatives (danisol-M) is mixed at 80 ~ 82 ℃ completely dissolved to form a primary mixture The primary mixture was purified water (DI-Water), EDTA-2Na (ethylene diamine tera acetic acid disodium salt diharate), dipotassium glycyrrhizinate (DPG), polyethylene glycol-4000S (PEG-4000S; ployetylene grycogen-4000s), aminocoat (Bemino), Lubrazel (Lubrajel DV), Carbopol 940 (Carbopol 940; Carboxy Vinyl Polymer), Carbopol 941 (Carbopol 941; Carboxy Vinyl Polymer), Natrasol 250HR; Hydroxy Ethyl Cellulose) and hydroxy acid (HA1%) were sequentially added thereto, followed by complete dispersion at 50˜52 ° C. for 10 minutes to form a secondary mixture. At this time, 0.3% by weight of phenoxyethanol was added to the total weight of the composition, 0.15% by weight of a preservative, and 0.03% by weight of EDTA-2Na.

이와 같이 조성된 2차 혼합물에 정제수와 중화제인 TEA(Triethanol Amine; 조성물의 총 중량에 0.28중량%)를 투입후 48~50℃에서 5분 동안 완전 분산한 후, 재차 가용화제인 Nikkol HCO-40(POE(Polyoxyethylene)-40 Hydrogenated Castor Oil)와 KXCM2184를 투입후 43~45℃에서 5분 동안 완전 분산한 다음, 상기 참고예 1 내지 6과 같이 얻은 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물을 조성물의 총 중량에 10중량%를 각각 차례로 투입후 40~42℃에서 5분 동안 분산하고, 이어서 32℃에서 냉각 종료 후 탈포(脫泡) 및 여과과정을 거쳐 로션 상의 화장료 조성물을 수득하였다.Purified water and neutralizing agent TEA (Triethanol Amine; 0.28% by weight of the total weight of the composition) was added to the secondary mixture thus prepared, completely dispersed at 48-50 ° C. for 5 minutes, and then again, a solubilizing agent Nikkol HCO-40 ( After adding POE (Polyoxyethylene) -40 Hydrogenated Castor Oil) and KXCM2184, it was completely dispersed at 43∼45 ° C. for 5 minutes, and then obtained as crystals, Aloe Vera gel, Foucault Gel 1000PP, carrot extract, Cucumber extract, chamomile extract, grapefruit extract was added 10% by weight to the total weight of the composition in turn and then dispersed for 5 minutes at 40 ~ 42 ℃, followed by defoaming and filtration after cooling at 32 ℃ A cosmetic composition on lotion was obtained.

<실시예2><Example 2>

상기 참고예 1 내지 6과 같이 얻은 크리스탈좀, 알로에 베라겔, 푸코겔1000PP, 당근 추출물, 오이 추출물, 캐모마일 추출물, 자몽 추출물을 조성물의 총 중량에 각각0.0001중량%를 첨가하는 것만을 달리할 뿐, 그밖에 나머지는 상기 실시예2와 동일하게 하여, 로션 상의 화장료 조성물을 수득하였다.The crystals obtained as in Reference Examples 1 to 6, aloe vera gel, fucogel 1000PP, carrot extract, cucumber extract, chamomile extract, grapefruit extract is different only by adding 0.0001% by weight to the total weight of the composition, The rest was the same as in Example 2, to obtain a cosmetic composition on a lotion.

<실험예1><Experimental Example 1>

실시예 1-2에서 제조된 화장료 조성물들의 장기간 사용에 따른 피부 안정성을 평가하기 위해서 20-30대 건강한 남녀 40명을 대상으로 20일간 폐쇄첩포시험을 실시하였다. 시험대상자의 양팔의 상박부를 70% 이소프로필 알콜 수용액으로 세척하고, 이 부위에 화장용 조성물을 공지의 방법에 따라 폐쇄첩포하였다. 이때 첩포량은 단위면적당(㎠) 25마이크로리터씩으로 하였고 24시간이 경과한 후 시험 부위의 피부를 관찰하고 다음날 처음과 같은 방법으로 같은 부위에 동일 물질을 폐쇄첩포를 10회 반복하여 그 결과를 판정하였다. 그 결과는 피부 변화는 거의 발견할 수 없었다.In order to evaluate the skin stability according to the long-term use of the cosmetic compositions prepared in Example 1-2, a 40-day closed patch test was conducted on 40 healthy men and women in their 20s and 30s. The upper arms of both arms of the test subjects were washed with an aqueous 70% isopropyl alcohol solution, and the cosmetic composition was closed on the site according to a known method. At this time, the amount of patch was 25 microliters per unit area (cm2). After 24 hours, the skin of the test site was observed, and the result was determined by repeating the closed patch 10 times with the same substance on the same site as the first method the next day. It was. The result was almost no skin change.

<실험예2>Experimental Example 2

상기 실시 예1 내지 2로부터 수득한 조성물을 특히, 아토피 피부염과 비감염성 피부 질환이 있는 20 내지 40대의 남녀들을 무작위로 추출한 시험 군으로 하여 피부를 청결하게 한 후,아침저녁으로 하루에 2번씩 해당 피부에 발라서 1년 동안 사용하게 하였다. 그 후 시험자들의 피부를 검사한 결과, 기존의 3가지 역반응 없이 아토피 피부염과 비감염성 피부 질환이 완전히 개선되지는 않았으나, 피부 트러블이 완화됨을 확인할 수 있었다.The composition obtained in Examples 1 to 2, in particular, a test group randomly extracted men and women of 20 to 40 years with atopic dermatitis and non-infectious skin disease, and cleans the skin, and applies twice a day in the morning and evening Apply to skin and use for 1 year. Subsequently, as a result of examining the skin of the testers, it was confirmed that atopic dermatitis and non-infectious skin disease were not completely improved without three conventional reactions, but skin trouble was alleviated.

따라서 본 발명을 아토피 피부염과 비감염성 피부 질환과 같은 피부 트러블이 있는 사람들이 사용하는 경우에도 피부 트러블 없이 피부 개선을 할 수 있음을 간접적으로 알 수 있다. Therefore, it can be seen indirectly that even when the present invention is used by people with skin problems such as atopic dermatitis and non-infectious skin disease, the skin can be improved without skin trouble.

Claims (2)

화장료 조성물에는 크리스탈좀,알로에 베라겔, 푸코겔1000PP(NICI Name:Biosaccharide Gum-1), 당근 추출물, 오이 추출물, 캐모마일 추출물 및 자몽 추출물을 혼합하여 조성한 혼합추출물이 함유됨을 특징으로 하는 화장료 조성물.Cosmetic composition, characterized in that the cosmetic composition, aloe vera gel, Foucault gel 1000PP (NICI Name: Biosaccharide Gum-1), carrot extract, cucumber extract, chamomile extract and grapefruit extract is a mixed extract composition. 제1항에 있어서, 상기 화장료 조성물의 총중량에는 크리스탈좀0.0001~10중량%은 ,알로에 베라겔0.0001~10중량%, 푸코겔1000PP(NICI Name:Biosaccharide Gum-1)0.0001~10중량%, 당근 추출물0.0001~10중량%, 오이 추출물0.0001~10중량%, 캐모마일 추출물0.0001~10중량%, 자몽 추출물0.0001~10중량%가 함유됨을 특징으로 하는 화장료 조성물.According to claim 1, wherein the total weight of the cosmetic composition is 0.0001 to 10% by weight, Aloe vera gel 0.0001 to 10% by weight, Pucogel 1000PP (NICI Name: Biosaccharide Gum-1) 0.0001 to 10% by weight, carrot extract 0.0001 10 to 10% by weight, cucumber extract 0.0001 to 10% by weight, chamomile extract 0.0001 to 10% by weight, grapefruit extract 0.0001 to 10% by weight cosmetic composition characterized in that it contains.
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FR2943252A1 (en) * 2009-03-17 2010-09-24 Dermo Cosmetique Animale Lab D Oil in water dermo-cosmetic emulsion, useful to e.g. treat/prevent itching on animal skin other than man, comprises micelles having an oil having active ingredient to diffuse through skin, water in which polysaccharide is dissolved
AU2011247875B1 (en) * 2011-09-16 2012-08-09 Robert White Disinfectant Compositions and Uses Thereof
KR101202393B1 (en) 2010-06-01 2012-11-16 (주)선바이오텍 Herb extracts using living organic herbs, treatment composition for atopic dermatitis, and method of manufacturing thereof

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KR20080025036A (en) * 2005-03-23 2008-03-19 마리 케이 인코포레이티드 Skin lightening compositions

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KR100279073B1 (en) 1998-05-12 2001-02-01 윤동한 Cosmetic liquid composition comprising a multi-liquid crystal film capsule for cosmetics and a method of manufacturing the same and a multi-liquid crystal film capsule
KR20030015552A (en) * 2001-08-16 2003-02-25 강남석 Aesthetic pack composition and manufacturing method thereof
JP2004131500A (en) * 2002-09-19 2004-04-30 Fancl Corp Skin aging inhibitor or improver
KR20080025036A (en) * 2005-03-23 2008-03-19 마리 케이 인코포레이티드 Skin lightening compositions

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2943252A1 (en) * 2009-03-17 2010-09-24 Dermo Cosmetique Animale Lab D Oil in water dermo-cosmetic emulsion, useful to e.g. treat/prevent itching on animal skin other than man, comprises micelles having an oil having active ingredient to diffuse through skin, water in which polysaccharide is dissolved
KR101202393B1 (en) 2010-06-01 2012-11-16 (주)선바이오텍 Herb extracts using living organic herbs, treatment composition for atopic dermatitis, and method of manufacturing thereof
AU2011247875B1 (en) * 2011-09-16 2012-08-09 Robert White Disinfectant Compositions and Uses Thereof

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