CN113015894A - 一种推片机及样本染色方法 - Google Patents

一种推片机及样本染色方法 Download PDF

Info

Publication number
CN113015894A
CN113015894A CN201980074917.7A CN201980074917A CN113015894A CN 113015894 A CN113015894 A CN 113015894A CN 201980074917 A CN201980074917 A CN 201980074917A CN 113015894 A CN113015894 A CN 113015894A
Authority
CN
China
Prior art keywords
smear
reagent
control valve
blowing
dyeing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980074917.7A
Other languages
English (en)
Inventor
刘隐明
赖富兴
滕锦
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Mindray Bio Medical Electronics Co Ltd
Original Assignee
Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Mindray Bio Medical Electronics Co Ltd filed Critical Shenzhen Mindray Bio Medical Electronics Co Ltd
Publication of CN113015894A publication Critical patent/CN113015894A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/302—Stain compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G01N2001/307—Fixative compositions non-toxic, no Hg, no formaldehyde
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G01N2001/386—Other diluting or mixing processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00534—Mixing by a special element, e.g. stirrer
    • G01N2035/00544—Mixing by a special element, e.g. stirrer using fluid flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

一种推片机，包括：玻片装载机构(2)，用于装载玻片；加样机构(3)，用于将血样加载到玻片上；推片机构(4)，用于将玻片上的血样抹平以制成涂片；滴染机构(5)，用于将染色试剂和缓冲液滴至涂片；吹气机构，用于对涂片上的染色试剂和缓冲液进行吹气混匀，使染色试剂和缓冲液混合并均匀覆盖涂片以对涂片进行一次染色。

Description

PCT国内申请，说明书已公开。

Claims (18)

  1. PCT国内申请，权利要求书已公开。
CN201980074917.7A 2019-06-24 2019-06-24 一种推片机及样本染色方法 Pending CN113015894A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2019/092513 WO2020257963A1 (zh) 2019-06-24 2019-06-24 一种推片机及样本染色方法

Publications (1)

Publication Number Publication Date
CN113015894A true CN113015894A (zh) 2021-06-22

Family

ID=74061145

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980074917.7A Pending CN113015894A (zh) 2019-06-24 2019-06-24 一种推片机及样本染色方法

Country Status (3)

Country Link
US (1) US20220082480A1 (zh)
CN (1) CN113015894A (zh)
WO (1) WO2020257963A1 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117142094A (zh) * 2023-11-01 2023-12-01 山东仕达思生物产业有限公司 一种载玻片输送组件及染色装置

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3072171B1 (fr) * 2017-10-06 2021-02-19 Diagdev Dispositif et procede de coloration d'un element organique sur une lame

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780306A (en) * 1993-09-21 1998-07-14 Boehringer Mannheim Gmbh Method and system for mixing liquids
US20060024200A1 (en) * 2004-06-29 2006-02-02 Mizuho Nishikiori Clinical specimen processing apparatus
US20110250103A1 (en) * 2010-04-12 2011-10-13 Mccarthy Thomas Robert Multipurpose Sequential Droplet Applicator
CN203908840U (zh) * 2014-06-09 2014-10-29 马艳华 一种微电脑控制液基细胞制片染色系统
US20160363567A1 (en) * 2015-06-15 2016-12-15 Lunatech, Llc Vapor Device For Stressing And Analyzing Compounds
CN107957364A (zh) * 2017-11-30 2018-04-24 珠海贝索生物技术有限公司 一种自动染色装置
CN109652369A (zh) * 2019-02-28 2019-04-19 西湖生物医药科技(杭州)有限公司 利用外周血体外制备成熟红细胞的方法及制剂

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3357600B2 (ja) * 1998-02-18 2002-12-16 シスメックス株式会社 塗抹標本作製方法および装置
ES2435666T3 (es) * 2007-07-10 2013-12-20 Ventana Medical Systems, Inc. Aparato y método para el tratamiento de muestras biológicas
CN104777027B (zh) * 2015-03-25 2017-03-22 江苏硕世生物科技有限公司 多功能全自动革兰氏染色仪
CN106841069A (zh) * 2017-02-24 2017-06-13 北京挑战生物技术有限公司 一种葡萄糖氧化酶活性快速测定试剂盒及其检测方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5780306A (en) * 1993-09-21 1998-07-14 Boehringer Mannheim Gmbh Method and system for mixing liquids
US20060024200A1 (en) * 2004-06-29 2006-02-02 Mizuho Nishikiori Clinical specimen processing apparatus
US20110250103A1 (en) * 2010-04-12 2011-10-13 Mccarthy Thomas Robert Multipurpose Sequential Droplet Applicator
CN203908840U (zh) * 2014-06-09 2014-10-29 马艳华 一种微电脑控制液基细胞制片染色系统
US20160363567A1 (en) * 2015-06-15 2016-12-15 Lunatech, Llc Vapor Device For Stressing And Analyzing Compounds
CN107957364A (zh) * 2017-11-30 2018-04-24 珠海贝索生物技术有限公司 一种自动染色装置
CN109652369A (zh) * 2019-02-28 2019-04-19 西湖生物医药科技(杭州)有限公司 利用外周血体外制备成熟红细胞的方法及制剂

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117142094A (zh) * 2023-11-01 2023-12-01 山东仕达思生物产业有限公司 一种载玻片输送组件及染色装置
CN117142094B (zh) * 2023-11-01 2023-12-29 山东仕达思生物产业有限公司 一种载玻片输送组件及染色装置

Also Published As

Publication number Publication date
US20220082480A1 (en) 2022-03-17
WO2020257963A1 (zh) 2020-12-30

Similar Documents

Publication Publication Date Title
CN105699156A (zh) 一种用于载玻片上组织样品染色的全自动染色仪及使用方法
CN105571925B (zh) 用于载玻片上生物样品的染色模块及其染色方法
CN206096158U (zh) 自动液体处理系统
US20220082480A1 (en) Smear preparation machine and sample staining method
CN111366429A (zh) 涂片制备装置、涂片制备方法
US3400726A (en) Apparatus for treating of biological preparations
JP6603237B2 (ja) 自動標本処理システム及び顕微鏡スライドのマルチステップ処理
US20180128847A1 (en) Automatic analyzer
US20220026321A1 (en) Specimen processing systems, pipette assemblies and methods for preparing reagents
JPH06504115A (ja) 免疫組織化学のための自動的組織染色
US20220307951A1 (en) Contactless mixing using modulated air jets
WO2017110488A1 (ja) 自動分析装置および自動分析方法
WO2020258155A1 (zh) 推片机及其控制方法
CN113514306A (zh) 一种智能染色系统及方法
CN105910877A (zh) 全自动细胞染色仪
EP3207379B1 (en) Automated batch stainer for immunohistochemistry
CN105067816A (zh) 一种即用型抗体及其应用
JPH0798321A (ja) 液体試料分析装置
CN216594438U (zh) 一种全自动高通量多功能染色机
JPS5988084A (ja) 自動染色装置
CN215694175U (zh) 试剂操作台和染色机
WO2020258169A1 (zh) 样本染色方法、涂片制备设备及染色液组合
CN213632908U (zh) 一种涂片染色机
CN115820403A (zh) 一种原位杂交仪液路
CN1971240A (zh) 细胞、细菌涂片染色机

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination