CN112999106A - Natural moisturizing liquid and preparation method thereof - Google Patents

Natural moisturizing liquid and preparation method thereof Download PDF

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Publication number
CN112999106A
CN112999106A CN201911308770.1A CN201911308770A CN112999106A CN 112999106 A CN112999106 A CN 112999106A CN 201911308770 A CN201911308770 A CN 201911308770A CN 112999106 A CN112999106 A CN 112999106A
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CN
China
Prior art keywords
parts
stirring
liquid
irisin
natural moisturizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201911308770.1A
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Chinese (zh)
Inventor
季浩
卢魏魏
刘佳
阚建伟
窦长清
徐娟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Tiansheng Pharmaceutical Co Ltd
Original Assignee
Jiangsu Tiansheng Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Tiansheng Pharmaceutical Co Ltd filed Critical Jiangsu Tiansheng Pharmaceutical Co Ltd
Priority to CN201911308770.1A priority Critical patent/CN112999106A/en
Publication of CN112999106A publication Critical patent/CN112999106A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645Proteins of vegetable origin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86Polyethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/26Optical properties
    • A61K2800/262Transparent; Translucent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

Abstract

The invention discloses a natural moisturizing liquid which is mainly prepared from the following components: 1-5 parts of irisin, 0.1-2 parts of dipotassium glycyrrhizinate, 0.1-3 parts of liquiritigenin, 5-10 parts of glycerol, 0.1-0.5 part of sodium cocoyl isethionate, 0.1-1 part of composite sodium hyaluronate, 20-40 parts of polyglycerol ether and 40-70 parts of deionized water. The invention also discloses a preparation method of the composition. The natural moisturizing liquid disclosed by the invention takes natural plant extracts as main active ingredients, wherein the irigenin has the effects of diminishing inflammation, resisting bacteria, whitening, moisturizing and the like, the dipotassium glycyrrhizinate has the effects of resisting allergy and irritation, the transdermal absorption effect is good, and the liquiritigenin has the effects of resisting ulcer, resisting inflammation and the like.

Description

Natural moisturizing liquid and preparation method thereof
Technical Field
The invention relates to a natural moisturizing liquid and a preparation method thereof, belonging to the technical field of daily chemical articles.
Background
As more and more people realize that the core problem of skin care is better maintenance of the skin barrier function, skin moisturization naturally becomes an important step in basic skin care. However, due to the question of chemical ingredients, there is an increasing trend in the area of skin care products for consumers to skin care ingredients from natural materials.
The Chinese invention patent with the application number of 2016105410478 provides a moisturizing smoothing toner containing natural plant extract and a preparation method and application thereof. The moisturizing smoothing toner containing the natural plant extract provided by the invention comprises the following raw materials in percentage by weight: 2 to 4 percent of glycerin, 0.2 to 1 percent of 1, 3-butanediol, 1 to 3 percent of hyaluronic acid, 0.5 to 1 percent of polyglutamic acid, 1 to 3 percent of collagen, 0.03 to 0.05 percent of ethylene diamine tetraacetic acid disodium salt, 0.05 to 0.1 percent of essence, 0.2 to 0.4 percent of urea aldehyde, 0.01 to 0.03 percent of hydrogenated castor oil, 80 to 90 percent of water, 0.5 to 2 percent of a herba ophioidis jae extract, 0.5 to 2 percent of a iris extract, 0.5 to 2 percent of a hibiscus extract, 0.5 to 2 percent of a goldfish extract, 0.5 to 2 percent of a cactus extract and 2 to 3 percent of an aloe extract. The moisturizing smoothing toner provided by the invention is fresh, cool, smooth, mild and non-irritant, can clean the skin and supplement nutrients, and can also moisturize, lock water, moisten the skin and relieve various skin sensitivity problems. The main additives of the product are all from natural plants, and the product has the advantages of no toxicity, no harm, green environmental protection, simple manufacturing method, suitability for mass production and cost saving.
The water deficiency is one of the causes of skin sensitivity and even acne, when the moisture of the surface layer of the skin, namely the cuticle, reaches 20 to 25 percent and the water content is sufficient, the skin is soft, smooth and free from fine lines, the hand feeling is full of elasticity, and the resistance to sensitization factors such as seasonal changes, temperature changes, environmental factors and the like is enhanced. However, with age and poor skin care, the water in the stratum corneum is lost, and when the content is less than 10%, the skin becomes dry, fine lines, tight, rough, desquamation, redness and sensitivity.
At present, many formulations in the cosmetics industry are heavily used for chemically synthesized additive components, and in recent years, the safety of the synthesized components is being questioned, such as the famous dioxane event and the plasticizer event. The use of natural organic components is a major trend in the current cosmetic industry, is environment-friendly, has low irritation, does not have uncertain safety problems, has high customer acceptance, is beneficial to brand publicity and the like, and is a beneficial factor for using natural components in cosmetics.
However, the existing moisturizing products simply allow moisture to permeate into the dermis, have poor hydration degree, and have no difference between long-term use and short-term use.
Disclosure of Invention
The invention aims to solve the problems in the prior art and provides a natural moisturizing liquid and a preparation method thereof.
In order to achieve the aim, the invention adopts the following technical scheme that the novel natural moisturizing liquid comprises the following components in parts by weight:
1-5 parts of irisin;
0.1-2 parts of dipotassium glycyrrhizinate;
0.1-3 parts of liquiritigenin;
5-10 parts of glycerol;
0.1-0.5 part of sodium cocoyl isethionate;
0.1-1 part of composite sodium hyaluronate;
20-40 parts of polyglycerol ether;
40-70 parts of deionized water.
Preferably, the natural moisturizing liquid comprises the following components in parts by weight:
1-2 parts of irisin;
0.1-1 part of dipotassium glycyrrhizinate;
2-3 parts of liquiritigenin;
5-10 parts of glycerol;
0.1-0.2 part of sodium cocoyl isethionate;
0.5-1 part of composite sodium hyaluronate;
30-40 parts of polyglyceryl ether;
40-50 parts of deionized water.
More preferably, the natural moisturizing liquid comprises the following components in parts by weight:
2kg of irisin;
1kg of dipotassium glycyrrhizinate;
2kg of liquiritigenin;
10kg of glycerol;
0.2kg of sodium cocoyl isethionate;
1kg of compound sodium hyaluronate;
40kg of polyglyceryl ether;
44.5kg deionized water.
Preferably, the novel natural moisturizing liquid is prepared by the following steps:
s1: putting glycerol into a kettle, gradually adding the composite sodium hyaluronate and irisin under stirring, stirring after completely adding to uniformly disperse the powder, and taking out for later use;
s2: adding deionized water into the kettle, gradually adding dipotassium glycyrrhizinate and glycyrrhizin under stirring, adding, and stirring to dissolve uniformly;
s3: starting heating and stirring, gradually adding the standby liquid in the step S1 into the uniform liquid in the step S2, and uniformly stirring to obtain transparent liquid;
s4: and (4) starting stirring, gradually adding the sodium cocoyl isethionate and the polyglycerol ether into the transparent liquid obtained in the step (S3), continuously stirring to uniformly disperse the sodium cocoyl isethionate and the polyglycerol ether into the transparent liquid, and cooling to room temperature to obtain the transparent natural moisturizing liquid.
The invention has the advantages that:
(1) the natural moisturizing liquid disclosed by the invention takes natural plant extracts as main active ingredients, is simple in method, good in emulsifying effect, transparent, fast in absorption after being wiped on the skin, slow in water loss, good in moisturizing effect, and has the effects of diminishing inflammation, resisting allergy, whitening and the like;
(2) the components of the moisturizing liquid used in the invention are all natural components, so that the moisturizing liquid has high safety and good effect. Wherein, the irisin is a natural substance obtained by extracting and purifying iris tectorum and has the effects of diminishing inflammation, resisting bacteria, whitening skin, moisturizing and the like; the dipotassium glycyrrhizinate is a natural substance obtained by extracting and purifying liquorice, has the efficacy of anti-allergy and anti-irritation, and has good transdermal absorption effect; liquiritigenin is flavanone monomer compound existing in Glycyrrhrizae radix, and has physiological effects of resisting cancer, ulcer, inflammation and liver protection; the polyglyceryl ether is a glycerin adduct of 26 moles of ethylene oxide, has smooth and fine touch feeling as a humectant and a lubricant, can be used as a skin conditioner, has good compatibility with cationic, nonionic and anionic surfactants, and is stable in a wide pH range; the sodium hyaluronate is in a sodium salt form of hyaluronic acid, is a substance extracted from cockscomb, absorbs and retains a large amount of water in skin, effectively makes the skin plump, and has the effects of lubricating, moisturizing and repairing tissues;
(3) the preparation method of the natural moisturizing liquid has reasonable process, can ensure that the effective activity of each component substance is reserved, optimized and coordinately exerted, has good emulsification effect, and finally obtains the uniform and transparent moisturizing liquid.
Detailed Description
The invention is further illustrated, but is not intended to be limited, by the following specific examples:
example 1:
weighing 10Kg of glycerin, putting into a kettle, gradually adding 1Kg of composite sodium hyaluronate and 5Kg of irisin under the stirring state, completely adding, stirring to uniformly disperse the powder, and taking out for later use. Weighing 40kg of deionized water, putting into a kettle, gradually adding 2kg of dipotassium glycyrrhizinate and 3kg of glycyrrhizin under stirring, and stirring to dissolve uniformly after completely adding; starting heating and stirring, gradually adding the standby liquid into the mixture, and uniformly stirring the mixture to obtain transparent liquid; starting stirring, weighing 0.5kg of sodium cocoyl isethionate and 38.5kg of polyglyceryl ether, gradually adding into the transparent liquid, continuously stirring to uniformly disperse the mixture into the transparent liquid, and cooling to room temperature to obtain 100kg of transparent natural moisturizing liquid. After the moisturizing liquid is uniformly applied to the skin, the water loss rate of 10 hours is 7% in an air-conditioning environment at 25 ℃, and the moisturizing effect is good.
Example 2:
weighing 5kg of glycerin, putting into a kettle, gradually adding 0.1kg of composite sodium hyaluronate and 1kg of irisin under the stirring state, adding completely, stirring to uniformly disperse the powder, and taking out for later use. Weighing 70kg of deionized water, putting into a kettle, gradually adding 0.1kg of dipotassium glycyrrhizinate and 0.1kg of glycyrrhizin under stirring, and stirring to dissolve uniformly after adding completely; starting heating and stirring, gradually adding the standby liquid into the mixture, and uniformly stirring the mixture to obtain transparent liquid; starting stirring, weighing 0.1kg of sodium cocoyl isethionate and 23.6kg of polyglyceryl ether, gradually adding into the transparent liquid, continuously stirring to uniformly disperse into the transparent liquid, and cooling to room temperature to obtain 100kg of transparent natural moisturizing liquid. After the moisturizing liquid is uniformly applied to the skin, the water loss rate of 10 hours is 10% in an air-conditioning environment at 25 ℃, and the moisturizing effect is good.
Example 3:
weighing 10kg of glycerin, putting into a kettle, gradually adding 1kg of composite sodium hyaluronate and 2kg of irisin under the stirring state, stirring after completely adding to uniformly disperse the powder, and taking out for later use. Weighing 44.5kg of deionized water, putting into a kettle, gradually adding 1kg of dipotassium glycyrrhizinate and 1kg of glycyrrhizin under stirring, and stirring to dissolve uniformly after completely adding; starting heating and stirring, gradually adding the standby liquid into the mixture, and uniformly stirring the mixture to obtain transparent liquid; starting stirring, weighing 0.5kg of sodium cocoyl isethionate and 40kg of polyglyceryl ether, gradually adding into the transparent liquid, continuously stirring to uniformly disperse into the transparent liquid, and cooling to room temperature to obtain 100kg of transparent natural moisturizing liquid. After the moisturizing liquid is uniformly applied to the skin, the water loss rate of 10 hours is 5% in an air-conditioning environment at 25 ℃, and the moisturizing effect is good.
In conclusion, the natural moisturizing liquid takes natural plant extracts as main active ingredients, wherein irigenin has the effects of diminishing inflammation, resisting bacteria, whitening, moisturizing and the like, dipotassium glycyrrhizinate has the effects of resisting allergy and stimulation, the transdermal absorption effect is good, glycyrrhizin has the effects of resisting ulcer, resisting inflammation and the like, and after the synergistic effect of multiple components, the moisturizing liquid can be endowed with good moisturizing performance, and the water loss rate of 10 hours is 10% and the optimal example 3 can reach 5% under the air-conditioning environment of 25 ℃.
In the description herein, references to the description of the term "one embodiment," "some embodiments," "an example," "a specific example," or "some examples," etc., mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above do not necessarily refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
The foregoing illustrates and describes the principles, general features, and advantages of the present invention. It should be understood by those skilled in the art that the above embodiments do not limit the present invention in any way, and all technical solutions obtained by using equivalent alternatives or equivalent variations fall within the scope of the present invention.

Claims (4)

1. The natural moisturizing liquid is characterized by comprising the following components in parts by weight:
1-5 parts of irisin;
0.1-2 parts of dipotassium glycyrrhizinate;
0.1-3 parts of liquiritigenin;
5-10 parts of glycerol;
0.1-0.5 part of sodium cocoyl isethionate;
0.1-1 part of composite sodium hyaluronate;
20-40 parts of polyglycerol ether;
40-70 parts of deionized water.
2. The natural moisturizing liquid is characterized by comprising the following components in parts by weight:
1-2 parts of irisin;
0.1-1 part of dipotassium glycyrrhizinate;
2-3 parts of liquiritigenin;
5-10 parts of glycerol;
0.1-0.2 part of sodium cocoyl isethionate;
0.5-1 part of composite sodium hyaluronate;
30-40 parts of polyglyceryl ether;
40-50 parts of deionized water.
3. The natural moisturizing liquid is characterized by comprising the following components in parts by weight:
2kg of irisin;
1kg of dipotassium glycyrrhizinate;
2kg of liquiritigenin;
10kg of glycerol;
0.2kg of sodium cocoyl isethionate;
1kg of compound sodium hyaluronate;
40kg of polyglyceryl ether;
44.5kg deionized water.
4. A method of preparing the natural moisturizing fluid of claim 1, comprising the steps of:
s1: putting glycerol in parts by weight into a kettle, gradually adding the composite sodium hyaluronate and the irisin under the stirring state, stirring after completely adding the composite sodium hyaluronate and the irisin to uniformly disperse the powder, and taking out for later use;
s2: adding deionized water into the kettle, gradually adding dipotassium glycyrrhizinate and glycyrrhizin under stirring, adding, and stirring to dissolve uniformly;
s3: starting heating and stirring, gradually adding the standby liquid prepared in the step S1 into the uniform liquid in the step S2, and uniformly stirring to obtain transparent liquid;
s4: and (4) starting stirring, gradually adding the sodium cocoyl isethionate and the polyglycerol ether into the transparent liquid obtained in the step (S3), continuously stirring to uniformly disperse the sodium cocoyl isethionate and the polyglycerol ether into the transparent liquid, and cooling to room temperature to obtain the transparent natural moisturizing liquid.
CN201911308770.1A 2019-12-18 2019-12-18 Natural moisturizing liquid and preparation method thereof Pending CN112999106A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201911308770.1A CN112999106A (en) 2019-12-18 2019-12-18 Natural moisturizing liquid and preparation method thereof

Publications (1)

Publication Number Publication Date
CN112999106A true CN112999106A (en) 2021-06-22

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115670968A (en) * 2022-10-31 2023-02-03 梅晔生物医药股份有限公司 Composition and daily chemical product with anti-inflammatory and allergy-relieving effects

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450028A (en) * 2008-12-31 2009-06-10 桐乡市恒基生物科技有限公司 Efficient moisture-retention sodium hyaluronic acid raw-liquor
CN106265376A (en) * 2016-10-12 2017-01-04 宁波久瑞生物工程有限公司 A kind of speckle dispelling elite and preparation technology thereof
CN106349356A (en) * 2016-08-31 2017-01-25 广州健坤生物科技有限公司 Protein with irisin functional structure and application thereof
CN109846719A (en) * 2018-12-24 2019-06-07 深圳市琉璃光生物科技有限公司 A kind of maintenance silk mask and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450028A (en) * 2008-12-31 2009-06-10 桐乡市恒基生物科技有限公司 Efficient moisture-retention sodium hyaluronic acid raw-liquor
CN106349356A (en) * 2016-08-31 2017-01-25 广州健坤生物科技有限公司 Protein with irisin functional structure and application thereof
CN106265376A (en) * 2016-10-12 2017-01-04 宁波久瑞生物工程有限公司 A kind of speckle dispelling elite and preparation technology thereof
CN109846719A (en) * 2018-12-24 2019-06-07 深圳市琉璃光生物科技有限公司 A kind of maintenance silk mask and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115670968A (en) * 2022-10-31 2023-02-03 梅晔生物医药股份有限公司 Composition and daily chemical product with anti-inflammatory and allergy-relieving effects
CN115670968B (en) * 2022-10-31 2023-08-25 梅晔生物医药股份有限公司 Composition with anti-inflammatory and allergy-relieving effects and daily chemical product

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Application publication date: 20210622