CN112997063B - 用于血沉棕黄层成像的方法和装置 - Google Patents

用于血沉棕黄层成像的方法和装置 Download PDF

Info

Publication number
CN112997063B
CN112997063B CN201980073984.7A CN201980073984A CN112997063B CN 112997063 B CN112997063 B CN 112997063B CN 201980073984 A CN201980073984 A CN 201980073984A CN 112997063 B CN112997063 B CN 112997063B
Authority
CN
China
Prior art keywords
blood sample
centrifuged blood
centrifuged
processor
transparent container
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201980073984.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN112997063A (zh
Inventor
T·R·德雷克斯勒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ruifudi Health Science Co ltd
Revvity Health Sciences Inc
Original Assignee
Ruifudi Health Science Co ltd
PerkinElmer Health Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ruifudi Health Science Co ltd, PerkinElmer Health Sciences Inc filed Critical Ruifudi Health Science Co ltd
Publication of CN112997063A publication Critical patent/CN112997063A/zh
Application granted granted Critical
Publication of CN112997063B publication Critical patent/CN112997063B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D21/00—Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26—Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262—Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/70—Determining position or orientation of objects or cameras
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10141—Special mode during image acquisition
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/10—Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from different wavelengths
    • H04N23/12—Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from different wavelengths with one sensor only
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/56—Cameras or camera modules comprising electronic image sensors; Control thereof provided with illuminating means

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Theoretical Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Quality & Reliability (AREA)
  • Ecology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Mathematical Physics (AREA)
  • Signal Processing (AREA)
  • Multimedia (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201980073984.7A 2018-11-08 2019-10-23 用于血沉棕黄层成像的方法和装置 Active CN112997063B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/184,494 2018-11-08
US16/184,494 US11386551B2 (en) 2018-11-08 2018-11-08 Method and apparatus for buffy coat imaging
PCT/US2019/057535 WO2020096772A1 (en) 2018-11-08 2019-10-23 Method and apparatus for buffy coat imaging

Publications (2)

Publication Number Publication Date
CN112997063A CN112997063A (zh) 2021-06-18
CN112997063B true CN112997063B (zh) 2024-11-12

Family

ID=68582340

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980073984.7A Active CN112997063B (zh) 2018-11-08 2019-10-23 用于血沉棕黄层成像的方法和装置

Country Status (8)

Country Link
US (1) US11386551B2 (enExample)
EP (1) EP3877747B1 (enExample)
JP (1) JP7250925B2 (enExample)
KR (1) KR102504240B1 (enExample)
CN (1) CN112997063B (enExample)
AU (1) AU2019375858B2 (enExample)
CA (1) CA3118716A1 (enExample)
WO (1) WO2020096772A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102701980B1 (ko) * 2019-09-18 2024-09-02 엘지전자 주식회사 액체통에 담긴 액체의 수위를 산출하는 로봇 및 방법
JP7767027B2 (ja) * 2021-05-21 2025-11-11 株式会社日立ハイテク 生体試料測定装置
JP7847968B2 (ja) * 2021-11-08 2026-04-20 株式会社日立ハイテク 生体試料測定装置
CN114383520A (zh) * 2021-12-31 2022-04-22 杭州索唯技术有限公司 一种快速识别采血管内血液分层层面高度的测量系统
AU2023249174A1 (en) * 2022-04-05 2024-10-17 Aavantibio, Inc. Gradient ultracentrifugation automated collector
GB2617833A (en) * 2022-04-19 2023-10-25 Entia Ltd An analysis apparatus and method
CN117783104A (zh) * 2022-09-27 2024-03-29 深圳市帝迈生物技术有限公司 一种凝血检测方法及装置
JP7859957B2 (ja) * 2022-11-25 2026-05-15 株式会社日立ハイテク 検体容器撮像装置及び検体処理装置
CN116577289B (zh) * 2023-04-06 2025-09-23 北京市春立正达医疗器械股份有限公司 一种用于血细胞离心后组分分离方法
CN116086894B (zh) * 2023-04-10 2023-07-25 北京市春立正达医疗器械股份有限公司 一种分离后血细胞监测导向组件及方法
US20250258070A1 (en) * 2024-02-09 2025-08-14 Grail, Inc. Liquid processing system and related methods
EP4628121A1 (en) * 2024-03-28 2025-10-08 Fenwal, Inc. Dynamic adjustment of light intensity and/or signal amplification in a centrifuge optical sensor assembly

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011019576A1 (en) * 2009-08-13 2011-02-17 Siemens Healthcare Diagnostics Inc. Methods and apparatus for ascertaining interferents and physical dimensions in liquid samples and containers to be analyzed by a clinical analyzer
WO2017132169A1 (en) * 2016-01-28 2017-08-03 Siemens Healthcare Diagnostics Inc. Methods and apparatus for detecting an interferent in a specimen

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2501460B2 (ja) * 1988-03-23 1996-05-29 オリンパス光学工業株式会社 ヘマトクリット値の測定方法
JPH02195261A (ja) * 1989-01-25 1990-08-01 Shimadzu Corp 血清サンプリング装置
JPH0337568A (ja) * 1989-07-03 1991-02-18 Fuji Photo Film Co Ltd 生化学分析装置
JPH05312804A (ja) * 1991-04-03 1993-11-26 Keyence Corp 赤血球沈降速度の測定方法及び測定装置
JPH04372861A (ja) * 1991-06-24 1992-12-25 Fuji Photo Film Co Ltd 液面検出装置
JP3429345B2 (ja) * 1993-11-30 2003-07-22 セファテクノロジー株式会社 光投射位置制御装置および透明容器内試料の分量測定装置
JP3132342B2 (ja) 1995-07-07 2001-02-05 松下電器産業株式会社 検体検査方法及びその装置
JP2000162215A (ja) * 1998-11-30 2000-06-16 Ids:Kk 検体処理管体およびその搬送システム
JP2001108506A (ja) * 1999-10-13 2001-04-20 Aloka Co Ltd 層境界面検出装置
FR2858251B1 (fr) * 2003-07-29 2005-10-28 Diagyr Procede pour equilibrer un plateau rotatif d'une centrifugeuse et centrifugeuse mettant en oeuvre le procede
GB0422358D0 (en) * 2004-10-08 2004-11-10 Rts Thurnall Plc Determination of the boundaries between fractions and extraction of selected fractions in a fractional sample
WO2006106962A1 (ja) * 2005-03-31 2006-10-12 Kabushiki Kaisha Toshiba 蛍光測定装置、蛍光測定方法、蛍光測定用収納容器および蛍光測定用収納容器の製造方法
WO2008021626A2 (en) * 2006-08-17 2008-02-21 Caridianbct, Inc. Blood processing apparatus with robust automated process control
US9116129B2 (en) * 2007-05-08 2015-08-25 Idexx Laboratories, Inc. Chemical analyzer
WO2010148135A2 (en) * 2009-06-16 2010-12-23 Levine Robert A Harvesting target materials from centrifuged suspensions
US20110226045A1 (en) 2009-11-25 2011-09-22 Mcquillan Adrian Charles Liquid analysis system
KR20130029128A (ko) * 2010-07-23 2013-03-21 베크만 컬터, 인코포레이티드 실시간 pcr용 용기
US9476825B2 (en) * 2010-10-19 2016-10-25 Baxter International Inc. Optical imaging system with multiple imaging channel optical sensing
CN103477197B (zh) * 2011-01-21 2016-08-17 提拉诺斯公司 样品使用最大化的系统和方法
JP5414707B2 (ja) * 2011-01-31 2014-02-12 株式会社日立ハイテクノロジーズ 分析装置
JP6143584B2 (ja) * 2013-07-04 2017-06-07 株式会社日立ハイテクノロジーズ 検出装置および生体試料分析装置
WO2015159620A1 (ja) * 2014-04-17 2015-10-22 株式会社日立ハイテクノロジーズ 検体検査自動化システムおよびチェックモジュールならびに試料のチェック方法
CA2976769C (en) * 2015-02-17 2023-06-13 Siemens Healthcare Diagnostics Inc. Model-based methods and apparatus for classifying an interferent in specimens

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011019576A1 (en) * 2009-08-13 2011-02-17 Siemens Healthcare Diagnostics Inc. Methods and apparatus for ascertaining interferents and physical dimensions in liquid samples and containers to be analyzed by a clinical analyzer
WO2017132169A1 (en) * 2016-01-28 2017-08-03 Siemens Healthcare Diagnostics Inc. Methods and apparatus for detecting an interferent in a specimen

Also Published As

Publication number Publication date
CN112997063A (zh) 2021-06-18
BR112021008799A2 (pt) 2021-08-10
JP7250925B2 (ja) 2023-04-03
EP3877747A1 (en) 2021-09-15
US11386551B2 (en) 2022-07-12
KR102504240B1 (ko) 2023-02-27
EP3877747B1 (en) 2024-11-20
JP2022507121A (ja) 2022-01-18
US20200151870A1 (en) 2020-05-14
KR20210088663A (ko) 2021-07-14
WO2020096772A1 (en) 2020-05-14
AU2019375858B2 (en) 2024-07-25
AU2019375858A1 (en) 2021-05-27
CA3118716A1 (en) 2020-05-14

Similar Documents

Publication Publication Date Title
JP7250925B2 (ja) 軟膜撮像のための方法および装置
CN108474733B (zh) 用于表征样品容器和样品的方法和装置
EP3408648B1 (en) Methods and apparatus for imaging a specimen container and/or specimen using multiple exposures
CN112639482B (zh) 以端到端训练方式使用单深度神经网络的样本容器表征
US11085913B2 (en) Biological sample analyzer
US11333553B2 (en) Methods and apparatus for specimen characterization using hyperspectral imaging
JP2019537011A (ja) 試料の溶血、黄疸、脂肪血症、又は正常性を検出する方法、装置及び品質チェックモジュール
EP1810003B1 (en) Determination of the boundaries between fractions and extraction of selected fractions in a fractionated sample
CN112673261A (zh) 针对血清和血浆采样两者利用深度适应网络的用于hiln确定的方法和装置
CN113950620B (zh) 用于筛选生物样本的设备和过程
US12253533B2 (en) Methods and apparatus providing calibration of background illumination for sample and/or sample container characterization
BR112021008799B1 (pt) Processador e método de análise de amostra de sangue centrifugada
HK40041703A (en) Specimen container characterization using a single deep neural network in an end-to-end training fashion
HK1253667B (en) Methods and apparatus for characterizing a specimen container and specimen
HK1255411A1 (zh) 被适配成根据多个侧视图来量化试样的方法和装置

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
CB02 Change of applicant information
CB02 Change of applicant information

Country or region after: U.S.A.

Address after: Massachusetts, USA

Applicant after: Ruifudi Health Science Co.,Ltd.

Address before: Massachusetts, USA

Applicant before: PerkinElmer Health Sciences, Inc.

Country or region before: U.S.A.

GR01 Patent grant
GR01 Patent grant